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Volumn 32, Issue 3, 2008, Pages 227-234

Estimation of significance thresholds for genomewide association scans

Author keywords

Bonferroni; Eigenvalue; Multiple testing; Permutation test

Indexed keywords

ARTICLE; CONTROLLED STUDY; GENE MUTATION; GENETIC ASSOCIATION; GENOME ANALYSIS; GENOTYPE; HUMAN; LINEAR REGRESSION ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 42249087793     PISSN: 07410395     EISSN: 10982272     Source Type: Journal    
DOI: 10.1002/gepi.20297     Document Type: Article
Times cited : (540)

References (24)
  • 1
    • 33745279056 scopus 로고    scopus 로고
    • Evaluating coverage of genome-wide association studies
    • Barrett JC, Cardon LR. 2006. Evaluating coverage of genome-wide association studies. Nat Genet 38:659-662.
    • (2006) Nat Genet , vol.38 , pp. 659-662
    • Barrett, J.C.1    Cardon, L.R.2
  • 2
    • 0001677717 scopus 로고
    • Controlling the false discovery rate - a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. 1995. Controlling the false discovery rate - a practical and powerful approach to multiple testing. J R Stat Soc B 57:289-300.
    • (1995) J R Stat Soc B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 3
    • 0028151261 scopus 로고
    • Empirical threshold values for quantitative trait mapping
    • Churchill GA, Doerge RW. 1994. Empirical threshold values for quantitative trait mapping. Genetics 138:963-971.
    • (1994) Genetics , vol.138 , pp. 963-971
    • Churchill, G.A.1    Doerge, R.W.2
  • 4
    • 42249098291 scopus 로고    scopus 로고
    • P-values, false discovery rates, and Bayes factors: How should we assess the "significance" of genetic associations?
    • abstract
    • Clayton DG. 2003. P-values, false discovery rates, and Bayes factors: how should we assess the "significance" of genetic associations? Ann Hum Genet 67:630 (abstract).
    • (2003) Ann Hum Genet , vol.67 , pp. 630
    • Clayton, D.G.1
  • 5
    • 0035958687 scopus 로고    scopus 로고
    • Modeling household transmission of American trypanosomiasis
    • Cohen JE, Gürtler RE. 2001. Modeling household transmission of American trypanosomiasis. Science 293:694-698.
    • (2001) Science , vol.293 , pp. 694-698
    • Cohen, J.E.1    Gürtler, R.E.2
  • 6
    • 0344826563 scopus 로고    scopus 로고
    • Rank truncated product of P-values, with application to genomewide association scans
    • Dudbridge F, Koeleman BP. 2003. Rank truncated product of P-values, with application to genomewide association scans. Genet Epidemiol 25:360-366.
    • (2003) Genet Epidemiol , vol.25 , pp. 360-366
    • Dudbridge, F.1    Koeleman, B.P.2
  • 7
    • 4143076901 scopus 로고    scopus 로고
    • Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies
    • Dudbridge F, Koeleman BP. 2004. Efficient computation of significance levels for multiple associations in large studies of correlated data, including genomewide association studies. Am J Hum Genet 75:424-435.
    • (2004) Am J Hum Genet , vol.75 , pp. 424-435
    • Dudbridge, F.1    Koeleman, B.P.2
  • 8
    • 0035992248 scopus 로고    scopus 로고
    • Empirical Bayes methods and false discovery rates for microarrays
    • Efron B, Tibshirani R. 2002. Empirical Bayes methods and false discovery rates for microarrays. Genet Epidemiol 23:70-86.
    • (2002) Genet Epidemiol , vol.23 , pp. 70-86
    • Efron, B.1    Tibshirani, R.2
  • 10
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map of the human genome
    • International HapMap Consortium
    • International HapMap Consortium. 2005. A haplotype map of the human genome. Nature 437:1299-1320.
    • (2005) Nature , vol.437 , pp. 1299-1320
  • 11
    • 33846563409 scopus 로고    scopus 로고
    • Why most published research findings are false
    • Ioannidis JP. 2005. Why most published research findings are false. PLoS Med 2:e124.
    • (2005) PLoS Med , vol.2
    • Ioannidis, J.P.1
  • 12
    • 0028877463 scopus 로고
    • Genetic dissection of complex traits: Guidelines for interpreting and reporting linkage results
    • Lander ES, Kruglyak L. 1995. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 11:241-247.
    • (1995) Nat Genet , vol.11 , pp. 241-247
    • Lander, E.S.1    Kruglyak, L.2
  • 13
    • 3042562270 scopus 로고    scopus 로고
    • Genomics, prior probability, and statistical tests of multiple hypotheses
    • Manly KF, Nettleton D, Hwang JT. 2004. Genomics, prior probability, and statistical tests of multiple hypotheses. Genome Res 14:997-1001.
    • (2004) Genome Res , vol.14 , pp. 997-1001
    • Manly, K.F.1    Nettleton, D.2    Hwang, J.T.3
  • 14
    • 34347344976 scopus 로고    scopus 로고
    • A new multipoint method for genome-wide association studies by imputation of genotypes
    • Marchini J, Howie B, Myers S, McVean G, Donnelly P. 2007. A new multipoint method for genome-wide association studies by imputation of genotypes. Nat Genet 39:906-913.
    • (2007) Nat Genet , vol.39 , pp. 906-913
    • Marchini, J.1    Howie, B.2    Myers, S.3    McVean, G.4    Donnelly, P.5
  • 15
    • 0043048571 scopus 로고
    • Sequential tests for the detection of linkage
    • Morton NE. 1955. Sequential tests for the detection of linkage. Am J Hum Genet 7:277-318.
    • (1955) Am J Hum Genet , vol.7 , pp. 277-318
    • Morton, N.E.1
  • 17
    • 33745279392 scopus 로고    scopus 로고
    • Evaluating and improving power in whole-genome association studies using fixed marker sets
    • Pe'er I, de Bakker PI, Maller J, Yelensky R, Altshuler D, Daly MJ. 2006. Evaluating and improving power in whole-genome association studies using fixed marker sets. Nat Genet 38:663-667.
    • (2006) Nat Genet , vol.38 , pp. 663-667
    • Pe'er, I.1    de Bakker, P.I.2    Maller, J.3    Yelensky, R.4    Altshuler, D.5    Daly, M.J.6
  • 18
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. 1996. The future of genetic studies of complex human diseases. Science 273:1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 19
    • 84947402121 scopus 로고
    • Rectangular confidence regions for the means of multivariate normal distributions
    • Šidák Z. 1967. Rectangular confidence regions for the means of multivariate normal distributions. J Am Stat Assoc 78:626-633.
    • (1967) J Am Stat Assoc , vol.78 , pp. 626-633
    • Šidák, Z.1
  • 20
    • 1642399172 scopus 로고    scopus 로고
    • Betting odds and genetic associations
    • Thomas DC, Clayton DG. 2004. Betting odds and genetic associations. J Nat Cancer Inst 96:421-423.
    • (2004) J Nat Cancer Inst , vol.96 , pp. 421-423
    • Thomas, D.C.1    Clayton, D.G.2
  • 21
    • 1642295096 scopus 로고    scopus 로고
    • Assessing the probability that a positive report is false: An approach for molecular epidemiology studies
    • Wacholder S, Chanock S, Garcia-Closas M, El Ghormli L, Rothman N. 2004. Assessing the probability that a positive report is false: an approach for molecular epidemiology studies. J Nat Cancer Inst 96:434-442.
    • (2004) J Nat Cancer Inst , vol.96 , pp. 434-442
    • Wacholder, S.1    Chanock, S.2    Garcia-Closas, M.3    El Ghormli, L.4    Rothman, N.5
  • 22
    • 34547782270 scopus 로고    scopus 로고
    • A Bayesian measure of the probability of false discovery in genetic epidemiology studies
    • Wakefield J. 2007. A Bayesian measure of the probability of false discovery in genetic epidemiology studies. Am J Hum Genet 81:208-227.
    • (2007) Am J Hum Genet , vol.81 , pp. 208-227
    • Wakefield, J.1
  • 23
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • Wellcome Trust Case Control Consortium
    • Wellcome Trust Case Control Consortium. 2007. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447:661-678.
    • (2007) Nature , vol.447 , pp. 661-678


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