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Volumn 67, Issue 3, 2015, Pages 411-423

Natural product modulators to overcome multidrug resistance in cancer

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; CURCUMIN; DAIDZEIN; DAUNORUBICIN; DOXORUBICIN; FUMITREMORGIN C; GENISTEIN; HEPTANE DERIVATIVE; HERBACEOUS AGENT; LIPOSOME; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; NANOPARTICLE; NATURAL PRODUCT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; QUERCETIN; RESVERATROL; RETINOID X RECEPTOR; SILYMARIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNINDEXED DRUG; VINBLASTINE; ABCB1 PROTEIN, HUMAN; ABCG2 PROTEIN, HUMAN; BIOLOGICAL PRODUCT; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; TUMOR PROTEIN;

EID: 84926515395     PISSN: 01635581     EISSN: 15327914     Source Type: Journal    
DOI: 10.1080/01635581.2015.1002624     Document Type: Article
Times cited : (48)

References (153)
  • 1
    • 0032927941 scopus 로고    scopus 로고
    • Cancer multidrug resistance
    • Persidis A: Cancer multidrug resistance. Nat Biotechnol 17, 94-95, 1999.
    • (1999) Nat Biotechnol , vol.17 , pp. 94-95
    • Persidis, A.1
  • 2
    • 73949102380 scopus 로고    scopus 로고
    • Multidrug resistance in cancer
    • Baguley BC: Multidrug resistance in cancer. Methods Mol Biol 596, 1-14, 2010.
    • (2011) Methods Mol Biol , vol.596 , Issue.1-14
    • Baguley, B.C.1
  • 3
    • 0037457802 scopus 로고    scopus 로고
    • Mammalian drug efflux transporters of the atp binding cassette (abc) family: An overview
    • Schinkel AH and Jonker JW: Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview. Adv Drug Deliv Rev 55, 3-29, 2003.
    • (2003) Adv Drug Deliv Rev , vol.55 , pp. 3-29
    • Schinkel, A.H.1    Jonker, J.W.2
  • 4
    • 79953767571 scopus 로고    scopus 로고
    • Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy
    • Wu CP, Ohnuma S, and Ambudkar SV: Discovering natural product modulators to overcome multidrug resistance in cancer chemotherapy. Curr Pharm Biotechnol 12, 609-620, 2011.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 609-620
    • Wu, C.P.1    Ohnuma, S.2    Ambudkar, S.V.3
  • 5
    • 0034953105 scopus 로고    scopus 로고
    • The human atp-binding cassette (abc) transporter superfamily
    • Dean M, Hamon Y, Chimini G: The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res 42, 1007-1017, 2001.
    • (2001) J Lipid Res , vol.42 , pp. 1007-1017
    • Dean, M.1    Hamon, Y.2    Chimini, G.3
  • 6
    • 84856271899 scopus 로고    scopus 로고
    • The p-glycoprotein multidrug transporter
    • Sharom FJ: The P-glycoprotein multidrug transporter. Essays Biochem 50, 161-178, 2011.
    • (2011) Essays Biochem , vol.50 , pp. 161-178
    • Sharom, F.J.1
  • 7
    • 0030823912 scopus 로고    scopus 로고
    • P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain
    • Beaulieu E, Demeule M, Ghitescu L, and Beliveau R: P-glycoprotein is strongly expressed in the luminal membranes of the endothelium of blood vessels in the brain. Biochem J 326 (Pt 2), 539-544, 1997.
    • (1997) Biochem J , vol.326 , pp. 539-544
    • Beaulieu, E.1    Demeule, M.2    Ghitescu, L.3    Beliveau, R.4
  • 8
    • 84882696152 scopus 로고    scopus 로고
    • P-glycoprotein inhibition for optimal drug delivery
    • Amin ML: P-glycoprotein inhibition for optimal drug delivery. Drug Target Insights 7, 27-34, 2013.
    • (2013) Drug Target Insights , vol.7 , pp. 27-34
    • Amin, M.L.1
  • 9
    • 0842284169 scopus 로고    scopus 로고
    • Multidrug resistance p-glycoprotein: Crucial significance in drug disposition and interaction
    • Sun J, He ZG, Cheng G, Wang SJ, Hao XH, et al.: Multidrug resistance P-glycoprotein: crucial significance in drug disposition and interaction. Med Sci Monit 10, RA5-R14, 2004.
    • (2004) Med Sci Monit , vol.10 , pp. RA5-R14
    • Sun, J.1    He, Z.G.2    Cheng, G.3    Wang, S.J.4    Hao, X.H.5
  • 10
    • 77951049110 scopus 로고    scopus 로고
    • Constituents of carpobrotus edulis inhibit p-glycoprotein of mdr1-transfected mouse lymphoma cells
    • Martins A, Vasas A, Schelz Z, Viveiros M, Molnar J, et al.: Constituents of Carpobrotus edulis inhibit P-glycoprotein of MDR1-transfected mouse lymphoma cells. Anticancer Res 30, 829-835, 2010.
    • (2011) Anticancer Res , vol.30 , pp. 829-835
    • Martins, A.1    Vasas, A.2    Schelz, Z.3    Viveiros, M.4    Molnar, J.5
  • 11
    • 0030863293 scopus 로고    scopus 로고
    • Membrane topology of the multidrug resistance protein (mrp). A study of glycosylation-site mutants reveals an extracytosolic nh2 terminus
    • Hipfner DR, Almquist KC, Leslie EM, Gerlach JH, Grant CE, et al.: Membrane topology of the multidrug resistance protein (MRP). A study of glycosylation-site mutants reveals an extracytosolic NH2 terminus. J Biol Chem 272, 23623-23630, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 23623-23630
    • Hipfner, D.R.1    Almquist, K.C.2    Leslie, E.M.3    Gerlach, J.H.4    Grant, C.E.5
  • 12
    • 0032744001 scopus 로고    scopus 로고
    • Structural, mechanistic and clinical aspects of mrp1
    • Hipfner DR, Deeley RG, and Cole SP: Structural, mechanistic and clinical aspects of MRP1. Biochim Biophys Acta 1461, 359-376, 1999.
    • (1999) Biochim Biophys Acta , vol.1461 , pp. 359-376
    • Hipfner, D.R.1    Deeley, R.G.2    Cole, S.P.3
  • 13
    • 0033021424 scopus 로고    scopus 로고
    • Atp-And glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein mrp1
    • Renes J, de Vries EG, Nienhuis EF, Jansen PL, and Muller M: ATP-And glutathione-dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1. Br J Pharmacol 126, 681-688, 1999.
    • (1999) Br J Pharmacol , vol.126 , pp. 681-688
    • Renes, J.1    De Vries, E.G.2    Nienhuis, E.F.3    Jansen, P.L.4    Muller, M.5
  • 14
    • 0035879951 scopus 로고    scopus 로고
    • Influences of glutathione on anionic substrate efflux in tumour cells expressing the multidrug resistance-Associated protein mrp1
    • Bagrij T, Klokouzas A, Hladky SB, and Barrand MA: Influences of glutathione on anionic substrate efflux in tumour cells expressing the multidrug resistance-Associated protein, MRP1. Biochem Pharmacol 62, 199-206, 2001.
    • (2001) Biochem Pharmacol , vol.62 , pp. 199-206
    • Bagrij, T.1    Klokouzas, A.2    Hladky, S.B.3    Barrand, M.A.4
  • 15
    • 0029095763 scopus 로고
    • Role of glutathione in the export of compounds from cells by the multidrug-resistance-Associated protein
    • Zaman GJ, Lankelma J, van Tellingen O, Beijnen J, Dekker H, et al.: Role of glutathione in the export of compounds from cells by the multidrug-resistance-Associated protein. Proc Natl Acad Sci U S A 92, 7690-7694, 1995.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 7690-7694
    • Zaman, G.J.1    Lankelma, J.2    Van Tellingen, O.3    Beijnen, J.4    Dekker, H.5
  • 16
    • 26844463953 scopus 로고    scopus 로고
    • Multidrug resistanceassociated protein 1 (mrp1) mediated vincristine resistance: Effects of n-Acetylcysteine and buthionine sulfoximine
    • Akan I, Akan S, Akca H, Savas B, and Ozben T: Multidrug resistanceassociated protein 1 (MRP1) mediated vincristine resistance: effects of N-Acetylcysteine and Buthionine sulfoximine. Cancer Cell Int 5, 22, 2005.
    • (2005) Cancer Cell Int , vol.5 , pp. 22
    • Akan, I.1    Akan, S.2    Akca, H.3    Savas, B.4    Ozben, T.5
  • 17
    • 0028578004 scopus 로고
    • Overexpression of the gene encoding the multidrug resistance-Associated protein results in increased atp-dependent glutathione s-conjugate transport
    • Muller M, Meijer C, Zaman GJ, Borst P, Scheper RJ, et al.: Overexpression of the gene encoding the multidrug resistance-Associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc Natl Acad Sci U S A 91, 13033-13037, 1994.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 13033-13037
    • Muller, M.1    Meijer, C.2    Zaman, G.J.3    Borst, P.4    Scheper, R.J.5
  • 18
    • 84926524024 scopus 로고    scopus 로고
    • Microtiter plate technique for the measurement of glutathione in fresh and cryopreserved lymphoblasts using the enzyme recycling method
    • Kearns PR and Hall AG: Microtiter plate technique for the measurement of glutathione in fresh and cryopreserved lymphoblasts using the enzyme recycling method. Methods Mol Med 28, 83-90, 1999.
    • (1999) Methods Mol Med , vol.28 , pp. 83-90
    • Kearns, P.R.1    Hall, A.G.2
  • 19
    • 0030009305 scopus 로고    scopus 로고
    • Multidrug resistance protein (mrp)-mediated transport of leukotriene c4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport
    • Loe DW, Almquist KC, Deeley RG, and Cole SP: Multidrug resistance protein (MRP)-mediated transport of leukotriene C4 and chemotherapeutic agents in membrane vesicles. Demonstration of glutathione-dependent vincristine transport. J Biol Chem 271, 9675-9682, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 9675-9682
    • Loe, D.W.1    Almquist, K.C.2    Deeley, R.G.3    Cole, S.P.4
  • 20
    • 0032534064 scopus 로고    scopus 로고
    • Characterization of vincristine transport by the m(r) 190,000 multidrug resistance protein (mrp): Evidence for cotransport with reduced glutathione
    • Loe DW, Deeley RG, and Cole SP: Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione. Cancer Res 58, 5130-5136, 1998.
    • (1998) Cancer Res , vol.58 , pp. 5130-5136
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 21
    • 0028864695 scopus 로고
    • N-Acetylcysteine-promoted survival of pc12 cells is glutathione-independent but transcription-dependent
    • Yan CY, Ferrari G, and Greene LA: N-Acetylcysteine-promoted survival of PC12 cells is glutathione-independent but transcription-dependent. J Biol Chem 270, 26827-26832, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 26827-26832
    • Yan, C.Y.1    Ferrari, G.2    Greene, L.A.3
  • 22
    • 0034012019 scopus 로고    scopus 로고
    • Verapamil stimulates glutathione transport by the 190-kda multidrug resistance protein 1 (mrp1
    • Loe DW, Deeley RG, and Cole SP: Verapamil stimulates glutathione transport by the 190-kDa multidrug resistance protein 1 (MRP1). J Pharmacol Exp Ther 293, 530-538, 2000.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 530-538
    • Loe, D.W.1    Deeley, R.G.2    Cole, S.P.3
  • 23
    • 0035033774 scopus 로고    scopus 로고
    • Modulation of multidrug resistance protein 1 (mrp1/abcc1) transport and atpase activities by interaction with dietary flavonoids
    • Leslie EM, Mao Q, Oleschuk CJ, Deeley RG, and Cole SP: Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and atpase activities by interaction with dietary flavonoids. Mol Pharmacol 59, 1171-1180, 2001.
    • (2001) Mol Pharmacol , vol.59 , pp. 1171-1180
    • Leslie, E.M.1    Mao, Q.2    Oleschuk, C.J.3    Deeley, R.G.4    Cole, S.P.5
  • 25
    • 33644811431 scopus 로고    scopus 로고
    • The role of the human abcg2 multidrug transporter and its variants in cancer therapy and toxicology
    • Cervenak J, Andrikovics H, Ozvegy-Laczka C, Tordai A, Nemet K, et al.: The role of the human ABCG2 multidrug transporter and its variants in cancer therapy and toxicology. Cancer Lett 234, 62-72, 2006.
    • (2006) Cancer Lett , vol.234 , pp. 62-72
    • Cervenak, J.1    Andrikovics, H.2    Ozvegy-Laczka, C.3    Tordai, A.4    Nemet, K.5
  • 26
    • 0037180446 scopus 로고    scopus 로고
    • The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria
    • Jonker JW, Buitelaar M, Wagenaar E, Van Der Valk MA, Scheffer GL, et al.: The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria. Proc Natl Acad Sci U S A 99, 15649-15654, 2002.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15649-15654
    • Jonker, J.W.1    Buitelaar, M.2    Wagenaar, E.3    Van Der Valk, M.A.4    Scheffer, G.L.5
  • 27
    • 0141919551 scopus 로고    scopus 로고
    • The breast cancer resistance protein (bcrp1/abcg2 restricts exposure to the dietary carcinogen 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine
    • van Herwaarden AE, Jonker JW, Wagenaar E, Brinkhuis RF, Schellens JH, et al.: The breast cancer resistance protein (Bcrp1/Abcg2) restricts exposure to the dietary carcinogen 2-Amino-1-methyl-6-phenylimidazo [4,5-b] pyridine. Cancer Res; 63, 6447-6452, 2003.
    • (2003) Cancer Res , vol.63 , pp. 6447-6452
    • Van Herwaarden, A.E.1    Jonker, J.W.2    Wagenaar, E.3    Brinkhuis, R.F.4    Schellens, J.H.5
  • 28
    • 0038072903 scopus 로고    scopus 로고
    • The reversal of multidrug resistance: An update
    • Kellen JA: The reversal of multidrug resistance: an update. J Exp Ther Oncol 3, 5-13, 2003.
    • (2003) J Exp Ther Oncol , vol.3 , pp. 5-13
    • Kellen, J.A.1
  • 29
    • 58349102840 scopus 로고    scopus 로고
    • Cancer multidrug resistance (mdr): A major impediment to effective chemotherapy
    • Ullah MF: Cancer multidrug resistance (MDR): a major impediment to effective chemotherapy. Asian Pac J Cancer Prev 9, 1-6, 2008.
    • (2008) Asian Pac J Cancer Prev , vol.9 , pp. 1-6
    • Ullah, M.F.1
  • 30
    • 77952312245 scopus 로고    scopus 로고
    • Recent advances in the research of p-glycoprotein inhibitors
    • Yang K, Wu J, and Li X: Recent advances in the research of P-glycoprotein inhibitors. Biosci Trends 2, 137-146, 2008.
    • (2008) Biosci Trends , vol.2 , pp. 137-146
    • Yang, K.1    Wu, J.2    Li, X.3
  • 31
    • 79251514280 scopus 로고    scopus 로고
    • Structural and functional properties of human multidrug resistance protein 1 (mrp1/abcc1
    • He SM, Li R, Kanwar JR, and Zhou SF: Structural and functional properties of human multidrug resistance protein 1 (MRP1/ABCC1). Curr Med Chem 18, 439-481, 2011.
    • (2011) Curr Med Chem , vol.18 , pp. 439-481
    • He, S.M.1    Li, R.2    Kanwar, J.R.3    Zhou, S.F.4
  • 32
    • 0030001001 scopus 로고    scopus 로고
    • Clinical trials of p-glycoprotein reversal in solid tumours
    • Ferry DR, Traunecker H, and Kerr DJ: Clinical trials of P-glycoprotein reversal in solid tumours. Eur J Cancer 32A, 1070-1081, 1996.
    • (1996) Eur J Cancer , vol.32 , Issue.A , pp. 1070-1081
    • Ferry, D.R.1    Traunecker, H.2    Kerr, D.J.3
  • 33
    • 0037358040 scopus 로고    scopus 로고
    • Overcoming multidrug resistance in cancer: An update on the clinical strategy of inhibiting p-glycoprotein
    • Thomas H and Coley HM: Overcoming multidrug resistance in cancer: an update on the clinical strategy of inhibiting p-glycoprotein. Cancer Control 10, 159-165, 2003.
    • (2003) Cancer Control , vol.10 , pp. 159-165
    • Thomas, H.1    Coley, H.M.2
  • 34
    • 0242331085 scopus 로고    scopus 로고
    • Multidrug resistance reversal agents
    • Robert J and Jarry C: Multidrug resistance reversal agents. J Med Chem 46, 4805-4817, 2003.
    • (2003) J Med Chem , vol.46 , pp. 4805-4817
    • Robert, J.1    Jarry, C.2
  • 35
    • 33646568511 scopus 로고    scopus 로고
    • Mechanisms and strategies to overcome multiple drug resistance in cancer
    • Ozben T: Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett 580, 2903-2909, 2006.
    • (2006) FEBS Lett , vol.580 , pp. 2903-2909
    • Ozben, T.1
  • 36
    • 0242300641 scopus 로고    scopus 로고
    • New approach to vital analysis of functional activity in abc transporters (markers for multidrug resistance) in solid tumors by the method of flow cytofluorometry
    • Bogush TA, Zabotina TN, Bogush EA, Chmutin EF, Komov DV, et al.: New approach to vital analysis of functional activity in ABC transporters (markers for multidrug resistance) in solid tumors by the method of flow cytofluorometry. Bull Exp Biol Med 135, 482-488, 2003.
    • (2003) Bull Exp Biol Med , vol.135 , pp. 482-488
    • Bogush, T.A.1    Zabotina, T.N.2    Bogush, E.A.3    Chmutin, E.F.4    Komov, D.V.5
  • 37
    • 0026353317 scopus 로고
    • Resistance modification by psc-833, a novel non-immunosuppressive cyclosporin [corrected]
    • Twentyman PR and Bleehen NM: Resistance modification by PSC-833, a novel non-immunosuppressive cyclosporin [corrected]. Eur J Cancer; 27, 1639-1642, 1991.
    • (1991) Eur J Cancer , vol.27 , pp. 1639-1642
    • Twentyman, P.R.1    Bleehen, N.M.2
  • 38
    • 0033799839 scopus 로고    scopus 로고
    • Multidrug resistance (mdr) in cancer. Mechanisms, reversal using modulators of mdr and the role of mdr modulators in influencing the pharmacokinetics of anticancer drugs
    • Krishna R and Mayer LD: Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs. Eur J Pharm Sci 11, 265-283, 2000.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 265-283
    • Krishna, R.1    Mayer, L.D.2
  • 39
    • 0027429147 scopus 로고
    • Differential inhibition by cyclosporins of primary-Active atp-dependent transporters in the hepatocyte canalicular membrane
    • Bohme M, Buchler M, Muller M, and Keppler D: Differential inhibition by cyclosporins of primary-Active ATP-dependent transporters in the hepatocyte canalicular membrane. FEBS Lett 333, 193-196, 1993.
    • (1993) FEBS Lett , vol.333 , pp. 193-196
    • Bohme, M.1    Buchler, M.2    Muller, M.3    Keppler, D.4
  • 40
    • 0031738505 scopus 로고    scopus 로고
    • Dose-dependent effects of psc 833 on its tissue distribution and on the biliary excretion of endogenous substrates in rats
    • Song S, Suzuki H, Kawai R, Tanaka C, Akasaka I, et al.: Dose-dependent effects of PSC 833 on its tissue distribution and on the biliary excretion of endogenous substrates in rats. Drug Metab Dispos 26, 1128-1133, 1998.
    • (1998) Drug Metab Dispos , vol.26 , pp. 1128-1133
    • Song, S.1    Suzuki, H.2    Kawai, R.3    Tanaka, C.4    Akasaka, I.5
  • 41
    • 45749089027 scopus 로고    scopus 로고
    • Phase iii study of valspodar (psc 833) combined with paclitaxel and carboplatin compared with paclitaxel and carboplatin alone in patients with stage iv or suboptimally debulked stage iii epithelial ovarian cancer or primary peritoneal cancer
    • Lhomme C, Joly F, Walker JL, Lissoni AA, Nicoletto MO, et al.: Phase III study of valspodar (PSC 833) combined with paclitaxel and carboplatin compared with paclitaxel and carboplatin alone in patients with stage IV or suboptimally debulked stage III epithelial ovarian cancer or primary peritoneal cancer. J Clin Oncol 26, 2674-2682, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 2674-2682
    • Lhomme, C.1    Joly, F.2    Walker, J.L.3    Lissoni, A.A.4    Nicoletto, M.O.5
  • 42
    • 84887992978 scopus 로고    scopus 로고
    • Different strategies to overcome multidrug resistance in cancer
    • Saraswathy M and Gong S: Different strategies to overcome multidrug resistance in cancer. Biotechnol Adv 31, 1397-1407, 2013.
    • (2013) Biotechnol Adv , vol.31 , pp. 1397-1407
    • Saraswathy, M.1    Gong, S.2
  • 43
    • 0345411341 scopus 로고    scopus 로고
    • P-glycoprotein and cytochrome p-450 3a inhibition: Dissociation of inhibitory potencies
    • Wandel C, Kim RB, Kajiji S, Guengerich P, Wilkinson GR, et al.: P-glycoprotein and cytochrome P-450 3A inhibition: dissociation of inhibitory potencies. Cancer Res 59, 3944-3948, 1999.
    • (1999) Cancer Res , vol.59 , pp. 3944-3948
    • Wandel, C.1    Kim, R.B.2    Kajiji, S.3    Guengerich, P.4    Wilkinson, G.R.5
  • 44
    • 0035883604 scopus 로고    scopus 로고
    • A phase i study of infusional vinblastine in combination with the p-glycoprotein antagonist psc 833 (valspodar
    • Bates S, Kang M, Meadows B, Bakke S, Choyke P, et al.: A Phase I study of infusional vinblastine in combination with the P-glycoprotein antagonist PSC 833 (valspodar). Cancer 92, 1577-1590, 2001.
    • (2001) Cancer , vol.92 , pp. 1577-1590
    • Bates, S.1    Kang, M.2    Meadows, B.3    Bakke, S.4    Choyke, P.5
  • 45
    • 0345084436 scopus 로고    scopus 로고
    • The multidrug resistance modulator valspodar (psc 833) is metabolized by human cytochrome p450 3a implications for drug-drug interactions and pharmacological activity of the main metabolite
    • Fischer V, Rodriguez-Gascon A, Heitz F, Tynes R, Hauck C, et al.: The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite. Drug Metab Dispos 26, 802-811, 1998.
    • (1998) Drug Metab Dispos , vol.26 , pp. 802-811
    • Fischer, V.1    Rodriguez-Gascon, A.2    Heitz, F.3    Tynes, R.4    Hauck, C.5
  • 46
    • 0034896260 scopus 로고    scopus 로고
    • The p-glycoprotein antagonist psc 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel
    • Kang MH, Figg WD, Ando Y, Blagosklonny MV, Liewehr D, et al.: The P-glycoprotein antagonist PSC 833 increases the plasma concentrations of 6alpha-hydroxypaclitaxel, a major metabolite of paclitaxel. Clin Cancer Res 7, 1610-1617, 2001.
    • (2001) Clin Cancer Res , vol.7 , pp. 1610-1617
    • Kang, M.H.1    Figg, W.D.2    Ando, Y.3    Blagosklonny, M.V.4    Liewehr, D.5
  • 47
    • 0013237486 scopus 로고    scopus 로고
    • Cancer multidrug resistance: A review of recent drug discovery research
    • Liscovitch M and Lavie Y: Cancer multidrug resistance: a review of recent drug discovery research. IDrugs 5, 349-355, 2002.
    • (2002) IDrugs , vol.5 , pp. 349-355
    • Liscovitch, M.1    Lavie, Y.2
  • 48
    • 65649121136 scopus 로고    scopus 로고
    • Design of new drug molecules to be used in reversing multidrug resistance in cancer cells
    • Mayur YC, Peters GJ, Prasad VV, Lemo C, and Sathish NK: Design of new drug molecules to be used in reversing multidrug resistance in cancer cells. Curr Cancer Drug Targets 9, 298-306, 2009.
    • (2009) Curr Cancer Drug Targets , vol.9 , pp. 298-306
    • Mayur, Y.C.1    Peters, G.J.2    Prasad, V.V.3    Lemo, C.4    Sathish, N.K.5
  • 49
    • 61449256570 scopus 로고    scopus 로고
    • Nn-bis (cyclohexanol)amine aryl esters: A new class of highly potent transporter-dependent multidrug resistance inhibitors
    • Martelli C, Alderighi D, Coronnello M, Dei S, Frosini M, et al.: N,N-bis (cyclohexanol)amine aryl esters: a new class of highly potent transporter-dependent multidrug resistance inhibitors. J Med Chem 52, 807-817, 2009.
    • (2009) J Med Chem , vol.52 , pp. 807-817
    • Martelli, C.1    Alderighi, D.2    Coronnello, M.3    Dei, S.4    Frosini, M.5
  • 50
    • 77649203312 scopus 로고    scopus 로고
    • Structureactivity relationships studies in a series of n,n-bis(alkanol)amine aryl esters as p-glycoprotein (pgp) dependent multidrug resistance (mdr) inhibitors
    • Martelli C, Coronnello M, Dei S, Manetti D, Orlandi F, et al.: Structureactivity relationships studies in a series of N,N-bis(alkanol)amine aryl esters as P-glycoprotein (Pgp) dependent multidrug resistance (MDR) inhibitors. J Med Chem 53, 1755-1762, 2010.
    • (2011) J Med Chem , vol.53 , pp. 1755-1762
    • Martelli, C.1    Coronnello, M.2    Dei, S.3    Manetti, D.4    Orlandi, F.5
  • 51
    • 0347755366 scopus 로고    scopus 로고
    • Reversing agents for atp-binding cassette (abc transporters: Application in modulating multidrug resistance (mdr
    • Lee CH: Reversing agents for ATP-binding cassette (ABC) transporters: application in modulating multidrug resistance (MDR). Curr Med Chem Anticancer Agents 4, 43-52, 2004.
    • (2004) Curr Med Chem Anticancer Agents , vol.4 , pp. 43-52
    • Lee, C.H.1
  • 52
    • 0034214366 scopus 로고    scopus 로고
    • Discovery and characterization of oc144-093, a novel inhibitor of pglycoprotein-mediated multidrug resistance
    • Newman MJ, Rodarte JC, Benbatoul KD, Romano SJ, Zhang C, et al.: Discovery and characterization of OC144-093, a novel inhibitor of Pglycoprotein-mediated multidrug resistance. Cancer Res 60, 2964-2972, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2964-2972
    • Newman, M.J.1    Rodarte, J.C.2    Benbatoul, K.D.3    Romano, S.J.4    Zhang, C.5
  • 53
    • 33745746815 scopus 로고    scopus 로고
    • Pharmacological strategies for overcoming multidrug resistance
    • Nobili S, Landini I, Giglioni B, and Mini E: Pharmacological strategies for overcoming multidrug resistance. Curr Drug Targets 7, 861-879, 2006.
    • (2006) Curr Drug Targets , vol.7 , pp. 861-879
    • Nobili, S.1    Landini, I.2    Giglioni, B.3    Mini, E.4
  • 54
    • 73949118463 scopus 로고    scopus 로고
    • Reversing agents for atp-binding cassette drug transporters
    • Lee CH: Reversing agents for ATP-binding cassette drug transporters. Methods Mol Biol 596, 325-340, 2010.
    • (2011) Methods Mol Biol , vol.596 , pp. 325-340
    • Lee, C.H.1
  • 55
    • 78549238612 scopus 로고    scopus 로고
    • Zosuquidar, a novel modulator of p-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: A randomized, placebo-controlled trial of the eastern cooperative oncology group 3999
    • Cripe LD, Uno H, Paietta EM, Litzow MR, Ketterling RP, et al.: Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999. Blood 116, 4077-4085, 2010.
    • (2011) Blood , vol.116 , pp. 4077-4085
    • Cripe, L.D.1    Uno, H.2    Paietta, E.M.3    Litzow, M.R.4    Ketterling, R.P.5
  • 57
    • 14644444547 scopus 로고    scopus 로고
    • Abc transporters in the balance: Is there a role in multidrug resistance?
    • Polgar O and Bates SE: ABC transporters in the balance: is there a role in multidrug resistance? Biochem Soc Trans 33, 241-245, 2005.
    • (2005) Biochem Soc Trans , vol.33 , pp. 241-245
    • Polgar, O.1    Bates, S.E.2
  • 58
    • 39749084704 scopus 로고    scopus 로고
    • Development of inhibitors of atp-binding cassette drug transporters: Present status and challenges
    • Shukla S, Wu CP, and Ambudkar SV: Development of inhibitors of ATP-binding cassette drug transporters: present status and challenges. Expert Opin Drug Metab Toxicol 4, 205-223, 2008.
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 205-223
    • Shukla, S.1    Wu, C.P.2    Ambudkar, S.V.3
  • 59
    • 0036881871 scopus 로고    scopus 로고
    • Abc transporters and inhibitors: New targets, new agents
    • Leonard GD, Polgar O, and Bates SE: ABC transporters and inhibitors: new targets, new agents. Curr Opin Investig Drugs 3, 1652-1659, 2002.
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 1652-1659
    • Leonard, G.D.1    Polgar, O.2    Bates, S.E.3
  • 60
    • 77958012076 scopus 로고    scopus 로고
    • Reversal of multidrug resitance by natural substances from plants
    • Molnar J, Engi H, Hohmann J, Molnar P, Deli J, et al.: Reversal of multidrug resitance by natural substances from plants. Curr Top Med Chem 10, 1757-1768, 2010.
    • (2011) Curr Top Med Chem , vol.10 , pp. 1757-1768
    • Molnar, J.1    Engi, H.2    Hohmann, J.3    Molnar, P.4    Deli, J.5
  • 61
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of atp-dependent transporters
    • Gottesman MM, Fojo T, and Bates SE: Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2, 48-58, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 62
    • 84887384756 scopus 로고    scopus 로고
    • Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition
    • Gelsomino G, Corsetto PA, Campia I, Montorfano G, Kopecka J, et al.: Omega 3 fatty acids chemosensitize multidrug resistant colon cancer cells by down-regulating cholesterol synthesis and altering detergent resistant membranes composition. Mol Cancer 12, 137, 2013.
    • (2013) Mol Cancer , vol.12 , Issue.137
    • Gelsomino, G.1    Corsetto, P.A.2    Campia, I.3    Montorfano, G.4    Kopecka, J.5
  • 63
    • 58149170576 scopus 로고    scopus 로고
    • Interaction of the p-glycoprotein multidrug efflux pump with cholesterol: Effects on atpase activity, drug binding and transport
    • Eckford PD and Sharom FJ: Interaction of the P-glycoprotein multidrug efflux pump with cholesterol: effects on ATPase activity, drug binding and transport. Biochemistry 47, 13686-13698, 2008.
    • (2008) Biochemistry , vol.47 , pp. 13686-13698
    • Eckford, P.D.1    Sharom, F.J.2
  • 64
    • 0037371275 scopus 로고    scopus 로고
    • Effects of the flavonoids biochanin a, morin, phloretin, and silymarin on p-glycoprotein-mediated transport
    • Zhang S, Morris ME: Effects of the flavonoids biochanin A, morin, phloretin, and silymarin on P-glycoprotein-mediated transport. J Pharmacol Exp Ther 304, 1258-1267, 2003.
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 1258-1267
    • Zhang, S.1    Morris, M.E.2
  • 65
    • 18244376403 scopus 로고    scopus 로고
    • Modulation by flavonoids of cell multidrug resistance mediated by p-glycoprotein and related abc transporters
    • Di Pietro A, Conseil G, Perez-Victoria JM, Dayan G, Baubichon-Cortay H, et al.: Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell Mol Life Sci 59, 307-322, 2002.
    • (2002) Cell Mol Life Sci , vol.59 , pp. 307-322
    • Di Pietro, A.1    Conseil, G.2    Perez-Victoria, J.M.3    Dayan, G.4    Baubichon-Cortay, H.5
  • 66
    • 0036720280 scopus 로고    scopus 로고
    • Recent advances in the discovery of flavonoids and analogs with high-Affinity binding to p-glycoprotein responsible for cancer cell multidrug resistance
    • Boumendjel A, Di Pietro A, Dumontet C, and Barron D: Recent advances in the discovery of flavonoids and analogs with high-Affinity binding to P-glycoprotein responsible for cancer cell multidrug resistance. Med Res Rev 22, 512-529, 2002.
    • (2002) Med Res Rev , vol.22 , pp. 512-529
    • Boumendjel, A.1    Di Pietro, A.2    Dumontet, C.3    Barron, D.4
  • 68
    • 1642385070 scopus 로고    scopus 로고
    • Structural requirements for the flavonoid-mediated modulation of glutathione s-transferase p1-1 and gs-x pump activity in mcf7 breast cancer cells
    • van Zanden JJ, Geraets L, Wortelboer HM, van Bladeren PJ, Rietjens IM, et al.: Structural requirements for the flavonoid-mediated modulation of glutathione S-transferase P1-1 and GS-X pump activity in MCF7 breast cancer cells. Biochem Pharmacol 67, 1607-1617, 2004.
    • (2004) Biochem Pharmacol , vol.67 , pp. 1607-1617
    • Van Zanden, J.J.1    Geraets, L.2    Wortelboer, H.M.3    Van Bladeren, P.J.4    Rietjens, I.M.5
  • 69
    • 25444524567 scopus 로고    scopus 로고
    • Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (abcc1 4 and 5
    • Wu CP, Calcagno AM, Hladky SB, Ambudkar SV, and Barrand MA: Modulatory effects of plant phenols on human multidrug-resistance proteins 1, 4 and 5 (ABCC1, 4 and 5). FEBS J 272, 4725-4740, 2005.
    • (2005) FEBS J , vol.272 , pp. 4725-4740
    • Wu, C.P.1    Calcagno, A.M.2    Hladky, S.B.3    Ambudkar, S.V.4    Barrand, M.A.5
  • 70
    • 0027482403 scopus 로고
    • Genistein modulates the decreased drug accumulation in non-pglycoprotein mediated multidrug resistant tumour cells
    • Versantvoort CH, Schuurhuis GJ, Pinedo HM, Eekman CA, Kuiper CM, et al.: Genistein modulates the decreased drug accumulation in non-Pglycoprotein mediated multidrug resistant tumour cells. Br J Cancer 68, 939-946, 1993.
    • (1993) Br J Cancer , vol.68 , pp. 939-946
    • Versantvoort, C.H.1    Schuurhuis, G.J.2    Pinedo, H.M.3    Eekman, C.A.4    Kuiper, C.M.5
  • 71
    • 84903879133 scopus 로고    scopus 로고
    • Collateral sensitivity of resistant mrp1-overexpressing cells to flavonoids and derivatives through gsh efflux
    • Lorendeau D, Dury L, Genoux-Bastide E, Lecerf-Schmidt F, Simoes-Pires C, et al.: Collateral sensitivity of resistant MRP1-overexpressing cells to flavonoids and derivatives through GSH efflux. Biochem Pharmacol 90, 235-245, 2014.
    • (2014) Biochem Pharmacol , vol.90 , pp. 235-245
    • Lorendeau, D.1    Dury, L.2    Genoux-Bastide, E.3    Lecerf-Schmidt, F.4    Simoes-Pires, C.5
  • 72
    • 84881189488 scopus 로고    scopus 로고
    • Formononetin potentiates epirubicin-induced apoptosis via ros production in hela cells in vitro
    • Lo YL and Wang W: Formononetin potentiates epirubicin-induced apoptosis via ROS production in HeLa cells in vitro. Chem Biol Interact 205, 188-197, 2013.
    • (2013) Chem Biol Interact , vol.205 , pp. 188-197
    • Lo, Y.L.1    Wang, W.2
  • 73
    • 33847307470 scopus 로고    scopus 로고
    • Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain
    • Joshi G, Hardas S, Sultana R, St Clair DK, Vore M, et al.: Glutathione elevation by gamma-glutamyl cysteine ethyl ester as a potential therapeutic strategy for preventing oxidative stress in brain mediated by in vivo administration of adriamycin: Implication for chemobrain. J Neurosci Res 85, 497-503, 2007.
    • (2007) J Neurosci Res , vol.85 , pp. 497-503
    • Joshi, G.1    Hardas, S.2    Sultana, R.3    St Clair, D.K.4    Vore, M.5
  • 74
    • 84904111274 scopus 로고    scopus 로고
    • Effect of st3gal 4 and fut 7 on sialyl lewis x synthesis and multidrug resistance in human acute myeloid leukemia
    • Ma H, Zhou H, Li P, Song X, Miao X, et al.: Effect of ST3GAL 4 and FUT 7 on sialyl Lewis X synthesis and multidrug resistance in human acute myeloid leukemia. Biochim Biophys Acta 1842, 1681-1692, 2014.
    • (2014) Biochim Biophys Acta , pp. 1681-1692
    • Ma, H.1    Zhou, H.2    Li, P.3    Song, X.4    Miao, X.5
  • 75
    • 79960439315 scopus 로고    scopus 로고
    • Resveratrol inhibits genisteininduced multi-drug resistance protein 2 (mrp2) expression in hepg2 cells
    • Kim JH, Chen C, and Tony KongAN: Resveratrol inhibits genisteininduced multi-drug resistance protein 2 (MRP2) expression in HepG2 cells. Arch Biochem Biophys 512, 160-166, 2011.
    • (2011) Arch Biochem Biophys , vol.512 , pp. 160-166
    • Kim, J.H.1    Chen, C.2    Tony Kong, A.N.3
  • 76
    • 0842348982 scopus 로고    scopus 로고
    • Flavonoids as inhibitors of mrp1-like efflux activity in human erythrocytes a structure-Activity relationship study
    • Bobrowska-Hagerstrand M, Wrobel A, Mrowczynska L, Soderstrom T, Shirataki Y, et al.: Flavonoids as inhibitors of MRP1-like efflux activity in human erythrocytes. A structure-Activity relationship study. Oncol Res 13, 463-469, 2003.
    • (2003) Oncol Res , vol.13 , pp. 463-469
    • Bobrowska-Hagerstrand, M.1    Wrobel, A.2    Mrowczynska, L.3    Soderstrom, T.4    Shirataki, Y.5
  • 77
    • 23044507172 scopus 로고    scopus 로고
    • Modulation of mrp1 protein transport by plant, and synthetically modified flavonoids
    • Lania-Pietrzak B, Michalak K, Hendrich AB, Mosiadz D, Grynkiewicz G, et al.: Modulation of MRP1 protein transport by plant, and synthetically modified flavonoids. Life Sci 77, 1879-1891, 2005.
    • (2005) Life Sci , vol.77 , pp. 1879-1891
    • Lania-Pietrzak, B.1    Michalak, K.2    Hendrich, A.B.3    Mosiadz, D.4    Grynkiewicz, G.5
  • 78
    • 63449112695 scopus 로고    scopus 로고
    • Perturbation of the lipid phase of a membrane is not involved in the modulation of mrp1 transport activity by flavonoids
    • Wesolowska O, Hendrich AB, Laniapietrzak B, Wisniewski J, Molnar J, et al.: Perturbation of the lipid phase of a membrane is not involved in the modulation of MRP1 transport activity by flavonoids. Cell Mol Biol Lett 14, 199-221, 2009.
    • (2009) Cell Mol Biol Lett , vol.14 , pp. 199-221
    • Wesolowska, O.1    Hendrich, A.B.2    Laniapietrzak, B.3    Wisniewski, J.4    Molnar, J.5
  • 79
    • 77955769712 scopus 로고    scopus 로고
    • 8-Prenylnaringenin is an inhibitor of multidrug resistance-Associated transporters, P-glycoprotein and MRP1
    • Wesolowska O, Wisniewski J, Sroda K, Krawczenko A, Bielawska-Pohl A, et al.: 8-Prenylnaringenin is an inhibitor of multidrug resistance-Associated transporters, P-glycoprotein and MRP1. Eur J Pharmacol 644, 32-40, 2010.
    • (2011) Eur J Pharmacol , vol.644 , pp. 32-40
    • Wesolowska, O.1    Wisniewski, J.2    Sroda, K.3    Krawczenko, A.4    Bielawska-Pohl, A.5
  • 80
    • 0028172728 scopus 로고
    • Modulation of adriamycin accumulation and efflux by flavonoids in hct-15 colon cells activation of p-glycoprotein as a putative mechanism
    • Critchfield JW, Welsh CJ, Phang JM, and Yeh GC: Modulation of adriamycin accumulation and efflux by flavonoids in HCT-15 colon cells. Activation of P-glycoprotein as a putative mechanism. Biochem Pharmacol 48, 1437-1445, 1994.
    • (1994) Biochem Pharmacol , vol.48 , pp. 1437-1445
    • Critchfield, J.W.1    Welsh, C.J.2    Phang, J.M.3    Yeh, G.C.4
  • 81
    • 0027981909 scopus 로고
    • Quercetin potentiates the effect of adriamycin in a multidrugresistant mcf-7 human breast-cancer cell line: P-glycoprotein as a possible target
    • Scambia G, Ranelletti FO, Panici PB, De Vincenzo R, Bonanno G, et al.: Quercetin potentiates the effect of adriamycin in a multidrugresistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother Pharmacol 34, 459-464, 1994.
    • (1994) Cancer Chemother Pharmacol , vol.34 , pp. 459-464
    • Scambia, G.1    Ranelletti, F.O.2    Panici, P.B.3    De Vincenzo, R.4    Bonanno, G.5
  • 82
    • 0030469817 scopus 로고    scopus 로고
    • Acceleration of mrpassociated efflux of rhodamine 123 by genistein and related compounds
    • Versantvoort CH, Rhodes T, and Twentyman PR: Acceleration of MRPassociated efflux of rhodamine 123 by genistein and related compounds. Br J Cancer 74, 1949-1954, 1996.
    • (1996) Br J Cancer , vol.74 , pp. 1949-1954
    • Versantvoort, C.H.1    Rhodes, T.2    Twentyman, P.R.3
  • 83
    • 0031581819 scopus 로고    scopus 로고
    • Effect of quercetin on hoechst 33342 transport by purified and reconstituted p-glycoprotein
    • Shapiro AB and Ling V: Effect of quercetin on Hoechst 33342 transport by purified and reconstituted P-glycoprotein. Biochem Pharmacol 53, 587-596, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 587-596
    • Shapiro, A.B.1    Ling, V.2
  • 84
    • 69949106198 scopus 로고    scopus 로고
    • Emerging significance of flavonoids as p-glycoprotein inhibitors in cancer chemotherapy
    • Bansal T, Jaggi M, Khar RK, and Talegaonkar S: Emerging significance of flavonoids as P-glycoprotein inhibitors in cancer chemotherapy. J Pharm Pharm Sci 12, 46-78, 2009.
    • (2009) J Pharm Pharm Sci , vol.12 , pp. 46-78
    • Bansal, T.1    Jaggi, M.2    Khar, R.K.3    Talegaonkar, S.4
  • 85
    • 84860498446 scopus 로고    scopus 로고
    • Interaction of phenothiazines, stilbenes and flavonoids with multidrug resistance-Associated transporters, p-glycoprotein and mrp1
    • Wesolowska O: Interaction of phenothiazines, stilbenes and flavonoids with multidrug resistance-Associated transporters, P-glycoprotein and MRP1. Acta Biochim Pol 58, 433-48, 2011.
    • (2011) Acta Biochim Pol , vol.58 , pp. 433-448
    • Wesolowska, O.1
  • 86
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • Aggarwal BB, Kumar A, and Bharti AC: Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res 23, 363-398, 2003.
    • (2003) Anticancer Res , vol.23 , pp. 363-398
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 87
    • 34447506459 scopus 로고    scopus 로고
    • Modulation of function of three abc drug transporters, p-glycoprotein (abcb1), mitoxantrone resistance protein (abcg2) and multidrug resistance protein 1 (abcc1) by tetrahydrocurcumin, a major metabolite of curcumin
    • Limtrakul P, Chearwae W, Shukla S, Phisalphong C, and Ambudkar SV: Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin. Mol Cell Biochem 296, 85-95, 2007.
    • (2007) Mol Cell Biochem , vol.296 , pp. 85-95
    • Limtrakul, P.1    Chearwae, W.2    Shukla, S.3    Phisalphong, C.4    Ambudkar, S.V.5
  • 88
    • 82755176687 scopus 로고    scopus 로고
    • Curcumin enhances the efficacy of chemotherapy by tailoring p65nfkappab-p300 cross-talk in favor of p53-p300 in breast cancer
    • Sen GS, Mohanty S, Hossain DM, Bhattacharyya S, Banerjee S, et al.: Curcumin enhances the efficacy of chemotherapy by tailoring p65NFkappaB-p300 cross-talk in favor of p53-p300 in breast cancer. J Biol Chem 286, 42232-42247, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 42232-42247
    • Sen, G.S.1    Mohanty, S.2    Hossain, D.M.3    Bhattacharyya, S.4    Banerjee, S.5
  • 89
    • 0035950034 scopus 로고    scopus 로고
    • The differential sensitivity of bc1-2-overexpressing human breast tumor cells to trail or doxorubicin-induced apoptosis is dependent on bc1-2 protein levels
    • Ruiz de Almodovar C, Ruiz-Ruiz C, Munoz-Pinedo C, Robledo G, and Lopez-Rivas A: The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels. Oncogene 20, 7128-7133, 2001.
    • (2001) Oncogene , vol.20 , pp. 7128-7133
    • Ruiz De Almodovar, C.1    Ruiz-Ruiz, C.2    Munoz-Pinedo, C.3    Robledo, G.4    Lopez-Rivas, A.5
  • 90
    • 17544367410 scopus 로고    scopus 로고
    • Induction of apoptosis by apo-2 ligand, a new member of the tumor necrosis factor cytokine family
    • Pitti RM, Marsters SA, Ruppert S, Donahue CJ, Moore A, et al.: Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271, 12687-12690, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 12687-12690
    • Pitti, R.M.1    Marsters, S.A.2    Ruppert, S.3    Donahue, C.J.4    Moore, A.5
  • 91
    • 33745854287 scopus 로고    scopus 로고
    • The role of the trail/trail receptors system in hematopoiesis and endothelial cell biology
    • Zauli G and Secchiero P: The role of the TRAIL/TRAIL receptors system in hematopoiesis and endothelial cell biology. Cytokine Growth Factor Rev 17, 245-257, 2006.
    • (2006) Cytokine Growth Factor Rev , vol.17 , pp. 245-257
    • Zauli, G.1    Secchiero, P.2
  • 92
    • 13344285339 scopus 로고
    • Identification and characterization of a new member of the tnf family that induces apoptosis
    • Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, et al.: Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 3, 673-682, 1995.
    • (1995) Immunity , vol.3 , pp. 673-682
    • Wiley, S.R.1    Schooley, K.2    Smolak, P.J.3    Din, W.S.4    Huang, C.P.5
  • 93
    • 33745658614 scopus 로고    scopus 로고
    • P-glycoprotein enhances trail-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor dr5
    • Park SJ, Wu CH, Choi MR, Najafi F, Emami A, et al.: P-glycoprotein enhances TRAIL-triggered apoptosis in multidrug resistant cancer cells by interacting with the death receptor DR5. Biochem Pharmacol 72, 293-307, 2006.
    • (2006) Biochem Pharmacol , vol.72 , pp. 293-307
    • Park, S.J.1    Wu, C.H.2    Choi, M.R.3    Najafi, F.4    Emami, A.5
  • 94
    • 39749093675 scopus 로고    scopus 로고
    • Curcumin sensitizes trail-resistant xenografts: Molecular mechanisms of apoptosis, metastasis and angiogenesis
    • Shankar S, Ganapathy S, Chen Q, and Srivastava RK: Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis. Mol Cancer 7, 16, 2008.
    • (2008) Mol Cancer , vol.7 , pp. 16
    • Shankar, S.1    Ganapathy, S.2    Chen, Q.3    Srivastava, R.K.4
  • 95
    • 33947427176 scopus 로고    scopus 로고
    • Curcumin enhances apo2l/trail-induced apoptosis in chemoresistant ovarian cancer cells
    • Wahl H, Tan L, Griffith K, Choi M, and Liu JR: Curcumin enhances Apo2L/TRAIL-induced apoptosis in chemoresistant ovarian cancer cells. Gynecol Oncol 105, 104-112, 2007.
    • (2007) Gynecol Oncol , vol.105 , pp. 104-112
    • Wahl, H.1    Tan, L.2    Griffith, K.3    Choi, M.4    Liu, J.R.5
  • 96
    • 67249106291 scopus 로고    scopus 로고
    • Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells
    • Ganta S and Amiji M: Coadministration of Paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol Pharm 6, 928-939, 2009.
    • (2009) Mol Pharm , vol.6 , pp. 928-939
    • Ganta, S.1    Amiji, M.2
  • 97
    • 77956879465 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin
    • Yan YD, Kim DH, Sung JH, Yong CS, and Choi HG: Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin. Int J Pharm 399, 116-120, 2010.
    • (2011) Int J Pharm , vol.399 , pp. 116-120
    • Yan, Y.D.1    Kim, D.H.2    Sung, J.H.3    Yong, C.S.4    Choi, H.G.5
  • 98
    • 0035174504 scopus 로고    scopus 로고
    • Phase i clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions
    • Cheng AL, Hsu CH, Lin JK, Hsu MM, Ho YF, et al.: Phase I clinical trial of curcumin, a chemopreventive agent, in patients with high-risk or pre-malignant lesions. Anticancer Res 21, 2895-2900, 2001.
    • (2001) Anticancer Res , vol.21 , pp. 2895-2900
    • Cheng, A.L.1    Hsu, C.H.2    Lin, J.K.3    Hsu, M.M.4    Ho, Y.F.5
  • 100
    • 84890436482 scopus 로고    scopus 로고
    • Diarylheptanoids from the bark of black alder inhibit the growth of sensitive and multi-drug resistant non-small cell lung carcinoma cells
    • Novakovic M, Pesic M, Trifunovic S, Vuckovic I, Todorovic N, et al.: Diarylheptanoids from the bark of black alder inhibit the growth of sensitive and multi-drug resistant non-small cell lung carcinoma cells. Phytochemistry 97, 46-54, 2014.
    • (2014) Phytochemistry , vol.97 , pp. 46-54
    • Novakovic, M.1    Pesic, M.2    Trifunovic, S.3    Vuckovic, I.4    Todorovic, N.5
  • 101
    • 84887140160 scopus 로고    scopus 로고
    • Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin
    • Kim TH, Shin YJ, Won AJ, Lee BM, Choi WS, et al.: Resveratrol enhances chemosensitivity of doxorubicin in multidrug-resistant human breast cancer cells via increased cellular influx of doxorubicin. Biochim Biophys Acta 1840, 615-625, 2014.
    • (2014) Biochim Biophys Acta , pp. 615-625
    • Kim, T.H.1    Shin, Y.J.2    Won, A.J.3    Lee, B.M.4    Choi, W.S.5
  • 102
    • 84888201758 scopus 로고    scopus 로고
    • Bitter melon extracts enhance the activity of chemotherapeutic agents through the modulation of multiple drug resistance
    • Kwatra D, Venugopal A, Standing D, Ponnurangam S, Dhar A, et al.: Bitter melon extracts enhance the activity of chemotherapeutic agents through the modulation of multiple drug resistance. J Pharm Sci 102, 4444-4454, 2013.
    • (2013) J Pharm Sci , vol.102 , pp. 4444-4454
    • Kwatra, D.1    Venugopal, A.2    Standing, D.3    Ponnurangam, S.4    Dhar, A.5
  • 103
    • 84893764885 scopus 로고    scopus 로고
    • Icaritin reverses multidrug resistance of hepg2/adr human hepatoma cells via downregulation of mdr1 and pglycoprotein expression
    • Sun L, Chen W, Qu L, Wu J, and Si J: Icaritin reverses multidrug resistance of HepG2/ADR human hepatoma cells via downregulation of MDR1 and Pglycoprotein expression. Mol Med Rep 8, 1883-1887, 2013.
    • (2013) Mol Med Rep , vol.8 , pp. 1883-1887
    • Sun, L.1    Chen, W.2    Qu, L.3    Wu, J.4    Si, J.5
  • 104
    • 84893857139 scopus 로고    scopus 로고
    • Pien tze huang suppresses the stem-like side population in colorectal cancer cells
    • Wei L, Chen P, Chen Y, Shen A, Chen H, et al.: Pien Tze Huang suppresses the stem-like side population in colorectal cancer cells. Mol Med Rep 9, 261-266, 2014.
    • (2014) Mol Med Rep , vol.9 , pp. 261-266
    • Wei, L.1    Chen, P.2    Chen, Y.3    Shen, A.4    Chen, H.5
  • 105
    • 0442313667 scopus 로고    scopus 로고
    • The influence of the p-glycoprotein inhibitor zosuquidar trihydrochloride (ly335979) on the brain penetration of paclitaxel in mice
    • Kemper EM, Cleypool C, Boogerd W, Beijnen JH, and van Tellingen O: The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice. Cancer Chemother Pharmacol 53, 173-178, 2004.
    • (2004) Cancer Chemother Pharmacol , vol.53 , pp. 173-178
    • Kemper, E.M.1    Cleypool, C.2    Boogerd, W.3    Beijnen, J.H.4    Van Tellingen, O.5
  • 106
    • 79955608537 scopus 로고    scopus 로고
    • Effects of ganoderic acid me on inhibiting multidrug resistance and inducing apoptosis in multidrug resistant colon cancer cells
    • Jianga Z, Jina T, Gaoa F, Liua J, Zhongb J, et al.: Effects of Ganoderic acid Me on inhibiting multidrug resistance and inducing apoptosis in multidrug resistant colon cancer cells. Process Biochemistry 46, 1307-1314, 2011.
    • (2011) Process Biochemistry , vol.46 , pp. 1307-1314
    • Jianga, Z.1    Jina, T.2    Gaoa, F.3    Liua, J.4    Zhongb, J.5
  • 107
    • 84869094020 scopus 로고    scopus 로고
    • Reversal of p-gp and mrp1-mediated multidrug resistance by h6, a gypenoside aglycon from gynostemma pentaphyllum, in vincristine-resistant human oral cancer (kb/vcr) cells
    • Zhu H, Liu Z, Tang L, Liu J, Zhou M, et al.: Reversal of P-gp and MRP1-mediated multidrug resistance by H6, a gypenoside aglycon from Gynostemma pentaphyllum, in vincristine-resistant human oral cancer (KB/VCR) cells. Eur J Pharmacol 696, 43-53, 2012.
    • (2012) Eur J Pharmacol , vol.696 , pp. 43-53
    • Zhu, H.1    Liu, Z.2    Tang, L.3    Liu, J.4    Zhou, M.5
  • 108
    • 40849083469 scopus 로고    scopus 로고
    • Effects of plant sterols on human multidrug transporters abcb1 and abcc1
    • Nabekura T, Yamaki T, Ueno K, Kitagawa S: Effects of plant sterols on human multidrug transporters ABCB1 and ABCC1. Biochem Biophys Res Commun 369, 363-368, 2008.
    • (2008) Biochem Biophys Res Commun , vol.369 , pp. 363-368
    • Nabekura, T.1    Yamaki, T.2    Ueno, K.3    Kitagawa, S.4
  • 109
    • 46449094523 scopus 로고    scopus 로고
    • Inhibitory effects of terpenoids on multidrug resistance-Associated protein 2-And breast cancer resistance protein-mediated transport
    • Yoshida N, Takada T, Yamamura Y, Adachi I, Suzuki H, et al.: Inhibitory effects of terpenoids on multidrug resistance-Associated protein 2-And breast cancer resistance protein-mediated transport. Drug Metab Dispos 36, 1206-1211, 2008.
    • (2008) Drug Metab Dispos , vol.36 , pp. 1206-1211
    • Yoshida, N.1    Takada, T.2    Yamamura, Y.3    Adachi, I.4    Suzuki, H.5
  • 110
    • 34247225559 scopus 로고    scopus 로고
    • Nonprenylated rotenoids a new class of potent breast cancer resistance protein inhibitors
    • Ahmed-Belkacem A, Macalou S, Borrelli F, Capasso R, Fattorusso E, et al.: Nonprenylated rotenoids, a new class of potent breast cancer resistance protein inhibitors. J Med Chem 50, 1933-1938, 2007.
    • (2007) J Med Chem , vol.50 , pp. 1933-1938
    • Ahmed-Belkacem, A.1    Macalou, S.2    Borrelli, F.3    Capasso, R.4    Fattorusso, E.5
  • 111
    • 3042569646 scopus 로고    scopus 로고
    • Phytoestrogens/flavonoids reverse breast cancer resistance protein/abcg2-mediated multidrug resistance
    • Imai Y, Tsukahara S, Asada S, and Sugimoto Y: Phytoestrogens/flavonoids reverse breast cancer resistance protein/ABCG2-mediated multidrug resistance. Cancer Res 64, 4346-4352, 2004.
    • (2004) Cancer Res , vol.64 , pp. 4346-4352
    • Imai, Y.1    Tsukahara, S.2    Asada, S.3    Sugimoto, Y.4
  • 112
    • 77952652033 scopus 로고    scopus 로고
    • Inhibitory effects of herbal extracts on breast cancer resistance protein (bcrp) and structure-inhibitory potency relationship of isoflavonoids
    • Tamaki H, Satoh H, Hori S, Ohtani H, and Sawada Y: Inhibitory effects of herbal extracts on breast cancer resistance protein (BCRP) and structure-inhibitory potency relationship of isoflavonoids. Drug Metab Pharmacokinet 25, 170-179, 2010.
    • (2011) Drug Metab Pharmacokinet , vol.25 , pp. 170-179
    • Tamaki, H.1    Satoh, H.2    Hori, S.3    Ohtani, H.4    Sawada, Y.5
  • 113
    • 0033966957 scopus 로고    scopus 로고
    • Fumitremorgin c reverses multidrug resistance in cells transfected with the breast cancer resistance protein
    • Rabindran SK, Ross DD, Doyle LA, Yang W, and Greenberger LM: Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res 60, 47-50, 2000.
    • (2000) Cancer Res , vol.60 , pp. 47-50
    • Rabindran, S.K.1    Ross, D.D.2    Doyle, L.A.3    Yang, W.4    Greenberger, L.M.5
  • 114
    • 0000890967 scopus 로고    scopus 로고
    • Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin c
    • Allen JD, van Loevezijn A, Lakhai JM, van der Valk M, van Tellingen O, et al.: Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C. Mol Cancer Ther 1, 417-425, 2002.
    • (2002) Mol Cancer Ther , vol.1 , pp. 417-425
    • Allen, J.D.1    Van Loevezijn, A.2    Lakhai, J.M.3    Van Der Valk, M.4    Van Tellingen, O.5
  • 115
    • 0037119057 scopus 로고    scopus 로고
    • Effects of herbal components on cdna-expressed cytochrome p450 enzyme catalytic activity
    • Zou L, Harkey MR, and Henderson GL: Effects of herbal components on cDNA-expressed cytochrome P450 enzyme catalytic activity. Life Sci 71, 1579-1589, 2002.
    • (2002) Life Sci , vol.71 , pp. 1579-1589
    • Zou, L.1    Harkey, M.R.2    Henderson, G.L.3
  • 116
    • 40949088898 scopus 로고    scopus 로고
    • Quercetin pretreatment increases the bioavailability of pioglitazone in rats: Involvement of cyp3a inhibition
    • Umathe SN, Dixit PV, Kumar V, Bansod KU, and Wanjari MM: Quercetin pretreatment increases the bioavailability of pioglitazone in rats: involvement of CYP3A inhibition. Biochem Pharmacol 75, 1670-1676, 2008.
    • (2008) Biochem Pharmacol , vol.75 , pp. 1670-1676
    • Umathe, S.N.1    Dixit, P.V.2    Kumar, V.3    Bansod, K.U.4    Wanjari, M.M.5
  • 117
    • 84876989587 scopus 로고    scopus 로고
    • Antitumor effect of 5-fluorouracil is enhanced by rosemary extract in both drug sensitive and resistant colon cancer cells
    • Gonzalez-Vallinas M, Molina S, Vicente G, de la Cueva A, Vargas T, et al.: Antitumor effect of 5-fluorouracil is enhanced by rosemary extract in both drug sensitive and resistant colon cancer cells. Pharmacol Res 72, 61-68, 2013.
    • (2013) Pharmacol Res , vol.72 , pp. 61-68
    • Gonzalez-Vallinas, M.1    Molina, S.2    Vicente, G.3    De La Cueva, A.4    Vargas, T.5
  • 118
    • 84868261155 scopus 로고    scopus 로고
    • Current status on marine products with reversal effect on cancer multidrug resistance
    • Abraham I, El Sayed K, Chen ZS, and Guo H: Current status on marine products with reversal effect on cancer multidrug resistance. Mar Drugs 10, 2312-2321, 2012.
    • (2012) Mar Drugs , vol.10 , pp. 2312-2321
    • Abraham, I.1    El Sayed, K.2    Chen, Z.S.3    Guo, H.4
  • 119
    • 84859588762 scopus 로고    scopus 로고
    • Reversal effects of components from the fruits of illicium simonsii on human adriamycin-resistant mcf-7 and 5-fluorouracil-resistant bel7402 cells
    • Wei DD, Wang JS, and Kong LY: Reversal effects of components from the fruits of Illicium simonsii on human Adriamycin-resistant MCF-7 and 5-fluorouracil-resistant Bel7402 cells. Phytother Res 26, 562-567, 2012.
    • (2012) Phytother Res , vol.26 , pp. 562-567
    • Wei, D.D.1    Wang, J.S.2    Kong, L.Y.3
  • 120
    • 84856225885 scopus 로고    scopus 로고
    • Molecular mechanisms underlying the role of micrornas (mirnas) in anticancer drug resistance and implications for clinical practice
    • Giovannetti E, Erozenci A, Smit J, Danesi R, and Peters GJ: Molecular mechanisms underlying the role of microRNAs (miRNAs) in anticancer drug resistance and implications for clinical practice. Crit Rev Oncol Hematol 81, 103-122, 2012.
    • (2012) Crit Rev Oncol Hematol , vol.81 , pp. 103-122
    • Giovannetti, E.1    Erozenci, A.2    Smit, J.3    Danesi, R.4    Peters, G.J.5
  • 121
    • 77950628416 scopus 로고    scopus 로고
    • Mechanisms of resistance to her family targeting antibodies
    • Kruser TJ and Wheeler DL: Mechanisms of resistance to HER family targeting antibodies. Exp Cell Res 316, 1083-1100, 2010.
    • (2011) Exp Cell Res , vol.316 , pp. 1083-1100
    • Kruser, T.J.1    Wheeler, D.L.2
  • 122
    • 84899995519 scopus 로고    scopus 로고
    • Mir-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of coppertransporting p-type adenosine triphosphatase a (atp7a
    • Song L, Li Y, Li W, Wu S, and Li Z: MiR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of coppertransporting P-type adenosine triphosphatase A (ATP7A). J Cell Biochem 115, 1234-1242, 2014.
    • (2014) J Cell Biochem , vol.115 , pp. 1234-1242
    • Song, L.1    Li, Y.2    Li, W.3    Wu, S.4    Li, Z.5
  • 123
    • 84890567462 scopus 로고    scopus 로고
    • By inhibiting src, verapamil and dasatinib overcome multidrug resistance via increased expression of bim and decreased expressions of mdr1 and survivin in human multidrug-resistant myeloma cells
    • Tsubaki M, Komai M, Itoh T, Imano M, Sakamoto K, et al.: By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells. Leuk Res 38, 121-130, 2014.
    • (2014) Leuk Res , vol.38 , pp. 121-130
    • Tsubaki, M.1    Komai, M.2    Itoh, T.3    Imano, M.4    Sakamoto, K.5
  • 124
    • 84871046413 scopus 로고    scopus 로고
    • Recent attempts at rnaimediated p-glycoprotein downregulation for reversal of multidrug resistance in cancer
    • Abbasi M, Lavasanifar A, and Uludag H: Recent attempts at RNAimediated P-glycoprotein downregulation for reversal of multidrug resistance in cancer. Med Res Rev 33, 33-53, 2013.
    • (2013) Med Res Rev , vol.33 , pp. 33-53
    • Abbasi, M.1    Lavasanifar, A.2    Uludag, H.3
  • 125
    • 84878230886 scopus 로고    scopus 로고
    • Hz08 inhibits the multi-drug resistance on multiple sites as the substrate of p-glycoprotein
    • Feng Y, Hu Y, Cen J, Darshika KN, Fang W, et al.: HZ08 inhibits the multi-drug resistance on multiple sites as the substrate of p-glycoprotein. Eur J Pharmacol 712, 53-59, 2013.
    • (2013) Eur J Pharmacol , vol.712 , pp. 53-59
    • Feng, Y.1    Hu, Y.2    Cen, J.3    Darshika, K.N.4    Fang, W.5
  • 127
    • 49249119415 scopus 로고    scopus 로고
    • A synthetic lethal therapeutic approach: Poly(adp) ribose polymerase inhibitors for the treatment of cancers deficient in dna double-strand break repair
    • Ashworth A: A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repair. J Clin Oncol 26, 3785-3790, 2008.
    • (2008) J Clin Oncol , vol.26 , pp. 3785-3790
    • Ashworth, A.1
  • 128
    • 77956657460 scopus 로고    scopus 로고
    • Poly (adp-ribose) polymerase as a novel therapeutic target in cancer
    • Annunziata CM and O'Shaughnessy J: Poly (ADP-ribose) polymerase as a novel therapeutic target in cancer. Clin Cancer Res 16, 4517-4526, 2010.
    • (2011) Clin Cancer Res , vol.16 , pp. 4517-4526
    • Annunziata, C.M.1    O'Shaughnessy, J.2
  • 129
    • 77955039099 scopus 로고    scopus 로고
    • Oral poly(adp-ribose) polymerase inhibitor olaparib in patients with brca1 or brca2 mutations and recurrent ovarian cancer: A proof-ofconcept trial
    • Audeh MW, Carmichael J, Penson RT, Friedlander M, Powell B, et al.: Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-ofconcept trial. Lancet 376, 245-251, 2010.
    • (2011) Lancet , vol.376 , pp. 245-251
    • Audeh, M.W.1    Carmichael, J.2    Penson, R.T.3    Friedlander, M.4    Powell, B.5
  • 130
    • 77955019276 scopus 로고    scopus 로고
    • Oral poly(adp-ribose) polymerase inhibitor olaparib in patients with brca1 or brca2 mutations and advanced breast cancer: A proof-ofconcept trial
    • Tutt A, Robson M, Garber JE, Domchek SM, Audeh MW, et al.: Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-ofconcept trial. Lancet 376, 235-244, 2010.
    • (2011) Lancet , vol.376 , pp. 235-244
    • Tutt, A.1    Robson, M.2    Garber, J.E.3    Domchek, S.M.4    Audeh, M.W.5
  • 131
    • 31044446360 scopus 로고    scopus 로고
    • Parp inhibitors for cancer therapy
    • Curtin NJ: PARP inhibitors for cancer therapy. Expert Rev Mol Med 7, 1-20, 2005.
    • (2005) Expert Rev Mol Med , vol.7 , pp. 1-20
    • Curtin, N.J.1
  • 132
    • 0033941729 scopus 로고    scopus 로고
    • Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines
    • Delaney CA, Wang LZ, Kyle S, White AW, Calvert AH, et al.: Potentiation of temozolomide and topotecan growth inhibition and cytotoxicity by novel poly(adenosine diphosphoribose) polymerase inhibitors in a panel of human tumor cell lines. Clin Cancer Res 6, 2860-2867, 2000.
    • (2000) Clin Cancer Res , vol.6 , pp. 2860-2867
    • Delaney, C.A.1    Wang, L.Z.2    Kyle, S.3    White, A.W.4    Calvert, A.H.5
  • 133
    • 84866071912 scopus 로고    scopus 로고
    • Enhancement of synthetic lethality via combinations of abt-888, a parp inhibitor, and carboplatin in vitro and in vivo using brca1 and brca2 isogenic models
    • Clark CC, Weitzel JN, and O'Connor TR: Enhancement of synthetic lethality via combinations of ABT-888, a PARP inhibitor, and carboplatin in vitro and in vivo using BRCA1 and BRCA2 isogenic models. Mol Cancer Ther 11, 1948-1958, 2012.
    • (2012) Mol Cancer Ther , vol.11 , pp. 1948-1958
    • Clark, C.C.1    Weitzel, J.N.2    O'Connor, T.R.3
  • 135
    • 84876443367 scopus 로고    scopus 로고
    • Effects of poly (adp-ribosyl) polymerase (parp) inhibitor on cisplatin resistance & proliferation of the ovarian cancer c13 cells
    • Zhang J, Kan Y, Tian Y, and Wang Z: Effects of poly (ADP-ribosyl) polymerase (PARP) inhibitor on cisplatin resistance & proliferation of the ovarian cancer C13 cells. Indian J Med Res 137, 527-532, 2013.
    • (2013) Indian J Med Res , vol.137 , pp. 527-532
    • Zhang, J.1    Kan, Y.2    Tian, Y.3    Wang, Z.4
  • 136
  • 137
    • 84872971914 scopus 로고    scopus 로고
    • Secondary mutations in brca2 associated with clinical resistance to a parp inhibitor
    • Barber LJ, Sandhu S, Chen L, Campbell J, Kozarewa I, et al.: Secondary mutations in BRCA2 associated with clinical resistance to a PARP inhibitor. J Pathol 229, 422-429, 2013.
    • (2013) J Pathol , vol.229 , pp. 422-429
    • Barber, L.J.1    Sandhu, S.2    Chen, L.3    Campbell, J.4    Kozarewa, I.5
  • 138
    • 84888880735 scopus 로고    scopus 로고
    • Particle carriers for combating multidrug-resistant cancer
    • Yan Y, Bjornmalm M, and Caruso F: Particle carriers for combating multidrug-resistant cancer. ACS Nano 7, 9512-9517, 2013.
    • (2013) ACS Nano , vol.7 , pp. 9512-9517
    • Yan, Y.1    Bjornmalm, M.2    Caruso, F.3
  • 140
  • 141
    • 79955009083 scopus 로고    scopus 로고
    • Antinuclear antibodies with nucleosome-restricted specificity for targeted delivery of chemotherapeutic agents
    • Torchilin VP: Antinuclear antibodies with nucleosome-restricted specificity for targeted delivery of chemotherapeutic agents. Ther Deliv 1, 257-272, 2010.
    • (2011) Ther Deliv , vol.1 , pp. 257-272
    • Torchilin, V.P.1
  • 142
    • 35848961893 scopus 로고    scopus 로고
    • Antitumor effect of paclitaxel-loaded pegylated immunoliposomes against human breast cancer cells
    • Yang T, Choi MK, Cui FD, Lee SJ, Chung SJ, et al.: Antitumor effect of paclitaxel-loaded PEGylated immunoliposomes against human breast cancer cells. Pharm Res 24, 2402-2411, 2007.
    • (2007) Pharm Res , vol.24 , pp. 2402-2411
    • Yang, T.1    Choi, M.K.2    Cui, F.D.3    Lee, S.J.4    Chung, S.J.5
  • 143
    • 84869427376 scopus 로고    scopus 로고
    • Nanodelivery strategies in cancer chemotherapy: Biological rationale and pharmaceutical perspectives
    • Mattheolabakis G, Rigas B, and Constantinides PP: Nanodelivery strategies in cancer chemotherapy: biological rationale and pharmaceutical perspectives. Nanomedicine (Lond) 7, 1577-1590, 2012.
    • (2012) Nanomedicine (Lond , vol.7 , pp. 1577-1590
    • Mattheolabakis, G.1    Rigas, B.2    Constantinides, P.P.3
  • 144
    • 84891821723 scopus 로고    scopus 로고
    • Doxorubicin in tat peptide-modified multifunctional immunoliposomes demonstrates increased activity against both drug-sensitive and drug-resistant ovarian cancer models
    • Apte A, Koren E, Koshkaryev A, and Torchilin VP: Doxorubicin in TAT peptide-modified multifunctional immunoliposomes demonstrates increased activity against both drug-sensitive and drug-resistant ovarian cancer models. Cancer Biol Ther 15, 69-80, 2014.
    • (2014) Cancer Biol Ther , vol.15 , pp. 69-80
    • Apte, A.1    Koren, E.2    Koshkaryev, A.3    Torchilin, V.P.4
  • 145
    • 84891373113 scopus 로고    scopus 로고
    • Co-delivery of chemotherapeutic drugs with vitamin e tpgs by porous plga nanoparticles for enhanced chemotherapy against multi-drug resistance
    • Zhu H, Chen H, Zeng X, Wang Z, Zhang X, et al.: Co-delivery of chemotherapeutic drugs with vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance. Biomaterials 35, 2391-2400, 2014.
    • (2014) Biomaterials , vol.35 , pp. 2391-2400
    • Zhu, H.1    Chen, H.2    Zeng, X.3    Wang, Z.4    Zhang, X.5
  • 146
    • 84888428832 scopus 로고    scopus 로고
    • Nanoparticle-directed subcellular localization of doxorubicin and the sensitization breast cancer cells by circumventing gst-mediated drug resistance
    • Zeng X, Morgenstern R, and Nystrom AM: Nanoparticle-directed subcellular localization of doxorubicin and the sensitization breast cancer cells by circumventing GST-Mediated drug resistance. Biomaterials 35, 1227-1239, 2014.
    • (2014) Biomaterials , vol.35 , pp. 1227-1239
    • Zeng, X.1    Morgenstern, R.2    Nystrom, A.M.3
  • 147
    • 84887017263 scopus 로고    scopus 로고
    • Integrated hollow mesoporous silica nanoparticles for target drug/sirna co-delivery
    • Ma X, Zhao Y, and Ng KW: Integrated hollow mesoporous silica nanoparticles for target drug/siRNA co-delivery. Chemistry 19, 15593-15603, 2013.
    • (2013) Chemistry , vol.19 , pp. 15593-15603
    • Ma, X.1    Zhao, Y.2    Ng, K.W.3
  • 148
    • 84876934723 scopus 로고    scopus 로고
    • Injectable nanomaterials for drug delivery: Carriers, targeting moieties, and therapeutics
    • Webster DM, Sundaram P, and Byrne ME: Injectable nanomaterials for drug delivery: carriers, targeting moieties, and therapeutics. Eur J Pharm Biopharm 84, 1-20, 2013.
    • (2013) Eur J Pharm Biopharm , vol.84 , pp. 1-20
    • Webster, D.M.1    Sundaram, P.2    Byrne, M.E.3
  • 149
    • 84891696537 scopus 로고    scopus 로고
    • Plga-carbon nanotube conjugates for intercellular delivery of caspase-3 into osteosarcoma cells
    • Cheng Q, Blais MO, Harris G, and Jabbarzadeh E: PLGA-carbon nanotube conjugates for intercellular delivery of caspase-3 into osteosarcoma cells. PLoS One 8, e81947, 2013.
    • (2013) PLoS One , vol.8 , pp. e81947
    • Cheng, Q.1    Blais, M.O.2    Harris, G.3    Jabbarzadeh, E.4
  • 151
    • 78650348824 scopus 로고    scopus 로고
    • Phase i and pharmacokinetic studies of cyt-6091, a novel pegylated colloidal gold-rhtnf nanomedicine
    • Libutti SK, Paciotti GF, Byrnes AA, Alexander HR, Jr., Gannon WE, et al.: Phase I and pharmacokinetic studies of CYT-6091, a novel PEGylated colloidal gold-rhTNF nanomedicine. Clin Cancer Res 16, 6139-6149, 2010.
    • (2011) Clin Cancer Res , vol.16 , pp. 6139-6149
    • Libutti, S.K.1    Paciotti, G.F.2    Byrnes, A.A.3    Alexander, H.R.4    Gannon, W.E.5
  • 152
    • 84889063414 scopus 로고    scopus 로고
    • Synergy effects of herb extracts: Pharmacokinetics and pharmacodynamic basis
    • Yang Y, Zhang Z, Li S, Ye X, Li X, et al.: Synergy effects of herb extracts: Pharmacokinetics and pharmacodynamic basis. Fitoterapia 92C, 133-147, 2013.
    • (2013) Fitoterapia , vol.92 C , pp. 133-147
    • Yang, Y.1    Zhang, Z.2    Li, S.3    Ye, X.4    Li, X.5
  • 153
    • 84888859758 scopus 로고    scopus 로고
    • Multicomponent phytotherapeutic approach gaining momentum: Is the one drug to fit all" model breaking down?
    • Rather MA, Bhat BA, and Qurishi MA: Multicomponent phytotherapeutic approach gaining momentum: Is the "one drug to fit all" model breaking down? Phytomedicine 21, 1-14, 2013.
    • (2013) Phytomedicine , vol.21 , pp. 1-14
    • Rather, M.A.1    Bhat, B.A.2    Qurishi, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.