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Volumn 3, Issue 1, 2003, Pages 5-13

The reversal of multidrug resistance: An update

Author keywords

[No Author keywords available]

Indexed keywords

5 [3 (4 DIPHENYLACETYL 1 PIPERAZINYL) 2 HYDROXYPROPOXY]QUINOLINE; ACRIDINE DERIVATIVE; AMITRIPTYLINE; APHIDICOLIN; AUREOBASIDIN A; BROMOCRIPTINE; BRYOSTATIN; CAFFEIC ACID; CANAVANINE; CANNABINOL; CEPHARANTHINE; CHALCONE DERIVATIVE; CYCLOSPORIN DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 3A4; CYTOCHROME P450 3A5; ELACRIDAR; FLAVOPIRIDOL; FLUPENTIXOL; GENISTEIN; GLYCOPROTEIN P; MIDOSTAURIN; OMEPRAZOLE; PENTOXIFYLLINE; PHENOTHIAZINE DERIVATIVE; PHENOXAZINE DERIVATIVE; RITONAVIR; TAXOID; UNINDEXED DRUG; ZOSUQUIDAR;

EID: 0038072903     PISSN: 13594117     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1359-4117.2003.01067.x     Document Type: Review
Times cited : (39)

References (95)
  • 1
    • 0033799839 scopus 로고    scopus 로고
    • Multidrug resistance (MDR) in cancer
    • Krishna R, Mayer LD. Multidrug resistance (MDR) in cancer. Eur J Pharm Sci 11: 265-283, 2000.
    • (2000) Eur J Pharm Sci , vol.11 , pp. 265-283
    • Krishna, R.1    Mayer, L.D.2
  • 2
    • 0033006305 scopus 로고
    • Multidrug resistance in oncology: Diagnostic and therapeutic approaches
    • Robert J. Multidrug resistance in oncology: diagnostic and therapeutic approaches. Eur J Clin Invest 29: 536-545, 1993.
    • (1993) Eur J Clin Invest , vol.29 , pp. 536-545
    • Robert, J.1
  • 3
    • 0035120672 scopus 로고    scopus 로고
    • Calcein assay for multidrug resistance reliable predicts therapy response and survival rate in acute myeloid leukemia
    • Karaszi E, Jakab K, Homolya L, et al. Calcein assay for multidrug resistance reliable predicts therapy response and survival rate in acute myeloid leukemia. Br J Haematol 112: 308-314, 2001.
    • (2001) Br J Haematol , vol.112 , pp. 308-314
    • Karaszi, E.1    Jakab, K.2    Homolya, L.3
  • 4
    • 0034094322 scopus 로고    scopus 로고
    • In vitro flow cytometry method to quantitatively assess inhibitors of P-glycoprotein
    • Wang EJ, Casciano CN, Clement RP, et al. In vitro flow cytometry method to quantitatively assess inhibitors of P-glycoprotein. Drug Metab Dispos 28: 522-526, 2000.
    • (2000) Drug Metab Dispos , vol.28 , pp. 522-526
    • Wang, E.J.1    Casciano, C.N.2    Clement, R.P.3
  • 5
    • 0034947674 scopus 로고    scopus 로고
    • From MDP, to MXR: New understanding of multidrug resistance systems, their properties and clinical significance
    • Litman T, Druley TE, Stein WD, et al. From MDP, to MXR: new understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci 58: 931-959, 2001.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 931-959
    • Litman, T.1    Druley, T.E.2    Stein, W.D.3
  • 6
    • 0036050988 scopus 로고    scopus 로고
    • The ability to overcome multidrug resistance of tumor cells with novel acridine cytostatics
    • Bontemps-Gracz MM, Kupiec A, Antonini I, et al. The ability to overcome multidrug resistance of tumor cells with novel acridine cytostatics. Acta Biochim Pol 49: 87-92, 2002.
    • (2002) Acta Biochim Pol , vol.49 , pp. 87-92
    • Bontemps-Gracz, M.M.1    Kupiec, A.2    Antonini, I.3
  • 7
    • 0032958446 scopus 로고    scopus 로고
    • Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo
    • Szabo D, Szabo G, Ocsovszki I, et al. Anti-psychotic drugs reverse multidrug resistance of tumor cell lines and human AML cells ex-vivo. Cancer Lett 139: 115-119, 1999.
    • (1999) Cancer Lett , vol.139 , pp. 115-119
    • Szabo, D.1    Szabo, G.2    Ocsovszki, I.3
  • 8
    • 0033136042 scopus 로고    scopus 로고
    • Modulation of drug resistance mediated by loss of mismatch repair by aphidicolin
    • Moreland NJ, Illand M, Kim UT, et al. Modulation of drug resistance mediated by loss of mismatch repair by aphidicolin. Cancer Res 59: 2102-2106, 1999.
    • (1999) Cancer Res , vol.59 , pp. 2102-2106
    • Moreland, N.J.1    Illand, M.2    Kim, U.T.3
  • 9
    • 0032054488 scopus 로고    scopus 로고
    • A novel areneisonitrile TC complex inhibits the transport activity of MDR P-glycoprotein
    • Rao VV, Herman LW, Kronauge JF, et al. A novel areneisonitrile TC complex inhibits the transport activity of MDR P-glycoprotein. Nucl Med Biol 25: 225-232, 1998.
    • (1998) Nucl Med Biol , vol.25 , pp. 225-232
    • Rao, V.V.1    Herman, L.W.2    Kronauge, J.F.3
  • 10
    • 0032212707 scopus 로고    scopus 로고
    • Synthesis of C-ring aromatic taxoids and evaluation of their multidrug resistance reversing activity
    • Morihira K, Nishimori T, Kusama H, et al. Synthesis of C-ring aromatic taxoids and evaluation of their multidrug resistance reversing activity. Bioorg Med Chem Lett 8: 2973-2976, 1998.
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 2973-2976
    • Morihira, K.1    Nishimori, T.2    Kusama, H.3
  • 11
    • 0033678688 scopus 로고    scopus 로고
    • Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein mediated secretion
    • Boyd RA, Stern RH, Steart Bh, et al. Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein mediated secretion. J Clin Pharmacol 40: 91-98, 2000.
    • (2000) J Clin Pharmacol , vol.40 , pp. 91-98
    • Boyd, R.A.1    Stern, R.H.2    Steart, B.H.3
  • 12
    • 0031899299 scopus 로고    scopus 로고
    • Aureobasidins as new inhibitors of P-glycoprotein in multidrug resistant tumor cells
    • Kurome T, Takesako K, Kato I. Aureobasidins as new inhibitors of P-glycoprotein in multidrug resistant tumor cells. J Antibiot 51: 353-358, 1998.
    • (1998) J Antibiot , vol.51 , pp. 353-358
    • Kurome, T.1    Takesako, K.2    Kato, I.3
  • 13
    • 0032561286 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein-mediated multidrug resistance in vitro by AV 200, a new ardeemin derivative
    • Mendez-Vidal C, Quesada AR. Reversal of P-glycoprotein-mediated multidrug resistance in vitro by AV200, a new ardeemin derivative. Cancer Lett 132: 45-50, 1998.
    • (1998) Cancer Lett , vol.132 , pp. 45-50
    • Mendez-Vidal, C.1    Quesada, A.R.2
  • 14
    • 0030995604 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein ATPase activity by beryllium fluoride
    • Sankaran B, Bhagat S, Senior AE. Inhibition of P-glycoprotein ATPase activity by beryllium fluoride. Biochemistry 36: 6847-6853, 1997.
    • (1997) Biochemistry , vol.36 , pp. 6847-6853
    • Sankaran, B.1    Bhagat, S.2    Senior, A.E.3
  • 15
    • 0031453281 scopus 로고    scopus 로고
    • Characterization of a novel bisacridone and comparison with PSC 833 as a potent and poorly reversible modulator of P-glycoprotein
    • Horton JK, Thimmaiah KN, Altenberg GA, et al. Characterization of a novel bisacridone and comparison with PSC 833 as a potent and poorly reversible modulator of P-glycoprotein. Mol Pharmacol 52: 948-957, 1997.
    • (1997) Mol Pharmacol , vol.52 , pp. 948-957
    • Horton, J.K.1    Thimmaiah, K.N.2    Altenberg, G.A.3
  • 16
    • 0009717724 scopus 로고    scopus 로고
    • Clinical studies of VX-710 (Biridocar, Incel), a small molecule inhibitor of the MDR-1 and MRP drug efflux pumps
    • November 3-6, New York, NY, (Abstract 51)
    • Demetri GD. Clinical studies of VX-710 (Biridocar, Incel), a small molecule inhibitor of the MDR-1 and MRP drug efflux pumps. Chemotherapy Foundation Symposium XVII, November 3-6, 1999, New York, NY, p. 66 (Abstract 51).
    • (1999) Chemotherapy Foundation Symposium XVII , pp. 66
    • Demetri, G.D.1
  • 17
    • 0030825773 scopus 로고    scopus 로고
    • Modulation of multidrug resistance by three bisbenzyl-isoquinolines in comparison with verapamil
    • Tian H, Pan Q-C. Modulation of multidrug resistance by three bisbenzyl-isoquinolines in comparison with verapamil. Acta Pharmacol Sin 18: 455-458, 1997.
    • (1997) Acta Pharmacol Sin , vol.18 , pp. 455-458
    • Tian, H.1    Pan, Q.-C.2
  • 18
    • 0032539760 scopus 로고    scopus 로고
    • Bromocriptine modulates P-glycoprotein Function
    • Orlowski S, Valente D, Garrigos M, et al. Bromocriptine modulates P-glycoprotein Function. BBRC 244: 481-488, 1998.
    • (1998) BBRC , vol.244 , pp. 481-488
    • Orlowski, S.1    Valente, D.2    Garrigos, M.3
  • 19
    • 0032190505 scopus 로고    scopus 로고
    • PKC-independent modulation of multidrug resistance in cells with mutant (V185) P-glycoprotein by Bryostatin 1
    • Spitaler M, Utz I, Hilbe W, et al. PKC-independent modulation of multidrug resistance in cells with mutant (V185) P-glycoprotein by Bryostatin 1. Biochem Pharmacol 56: 861-869, 1998.
    • (1998) Biochem Pharmacol , vol.56 , pp. 861-869
    • Spitaler, M.1    Utz, I.2    Hilbe, W.3
  • 20
    • 0030796173 scopus 로고    scopus 로고
    • Chemosensitizing activity of caffeic acid in multidrug-resistant MCF-7/Dox human breast carcinoma cells
    • Ahn C-C, Choi WC, Kong JY. Chemosensitizing activity of caffeic acid in multidrug-resistant MCF-7/Dox human breast carcinoma cells. Anticancer Res 17: 1913-1918, 1997.
    • (1997) Anticancer Res , vol.17 , pp. 1913-1918
    • Ahn, C.-C.1    Choi, W.C.2    Kong, J.Y.3
  • 21
    • 12444347131 scopus 로고    scopus 로고
    • Multidrug resistance reversal in tumor cells by some cannabis, ginzenizide and saffrone derivatives
    • October Kallithea, Greece (Abstract 218)
    • Molnar J, Szabo D, Berek L, et al. Multidrug resistance reversal in tumor cells by some cannabis, ginzenizide and saffrone derivatives. Sixth International Conference on Anticancer Research, October 1998, Kallithea, Greece (Abstract 218).
    • (1998) Sixth International Conference on Anticancer Research
    • Molnar, J.1    Szabo, D.2    Berek, L.3
  • 22
    • 0031054376 scopus 로고    scopus 로고
    • Modulation of multidrug resistance by cepha-rantine in fresh human gastrointestinal tumor cells
    • Hotta T, Tanimura H, Yamaue H, et al. Modulation of multidrug resistance by cepha-rantine in fresh human gastrointestinal tumor cells. Oncology 54: 153-157, 1997.
    • (1997) Oncology , vol.54 , pp. 153-157
    • Hotta, T.1    Tanimura, H.2    Yamaue, H.3
  • 23
    • 0033785762 scopus 로고    scopus 로고
    • Synthesis of a series of 3-cyanopropionamides and evaluation of their function as modulators of multidrug resistance
    • Ras F, Garcia R, Gallego P, et al. Synthesis of a series of 3-cyanopropionamides and evaluation of their function as modulators of multidrug resistance. Arch Pharm Med Chem 333: 329-336, 2000.
    • (2000) Arch Pharm Med Chem , vol.333 , pp. 329-336
    • Ras, F.1    Garcia, R.2    Gallego, P.3
  • 24
    • 0032782738 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein by cyclosporin A analogues and metabolites
    • Demeule M, Laplante A, Sepher-Arae A, et al. Inhibition of P-glycoprotein by cyclosporin A analogues and metabolites. Biochem Cell Biol 77: 47-58, 1999.
    • (1999) Biochem Cell Biol , vol.77 , pp. 47-58
    • Demeule, M.1    Laplante, A.2    Sepher-Arae, A.3
  • 25
    • 0008869282 scopus 로고    scopus 로고
    • Pregnane glycoside multi-drug-resistance modulators from Cynanchum wilfordii
    • Hwang BY, Kim SE, Kim YH, et al. Pregnane glycoside multi-drug-resistance modulators from Cynanchum wilfordii. J Nat Prod 62: 640-643, 1999.
    • (1999) J Nat Prod , vol.62 , pp. 640-643
    • Hwang, B.Y.1    Kim, S.E.2    Kim, Y.H.3
  • 26
    • 0030993792 scopus 로고    scopus 로고
    • Synthesis of Stipamide and a new multidrug resistance reversal agent, 6,7-dehydrostipamide
    • Andrus MB, Lepore SD. Synthesis of Stipamide and a new multidrug resistance reversal agent, 6,7-dehydrostipamide. J Am Chem Soc 119: 2327-2328, 1999.
    • (1999) J Am Chem Soc , vol.119 , pp. 2327-2328
    • Andrus, M.B.1    Lepore, S.D.2
  • 27
    • 0036011103 scopus 로고    scopus 로고
    • Estrone and 17beta-estradiol reverse breast cancer resistance
    • Imai Y, Tsukahara S, Shikawa E, et al. Estrone and 17beta-estradiol reverse breast cancer resistance. Jpn J Cancer Res 93: 231-235, 2002.
    • (2002) Jpn J Cancer Res , vol.93 , pp. 231-235
    • Imai, Y.1    Tsukahara, S.2    Shikawa, E.3
  • 28
    • 0029677298 scopus 로고    scopus 로고
    • In vivo reversibility of multidrug resistance by the MDR-modulator dexniguldipine
    • Dietel M, Boss H, Reymann A, et al. In vivo reversibility of multidrug resistance by the MDR-modulator dexniguldipine. J Exp Ther Oncol 1: 23-29, 1996.
    • (1996) J Exp Ther Oncol , vol.1 , pp. 23-29
    • Dietel, M.1    Boss, H.2    Reymann, A.3
  • 29
    • 0031738659 scopus 로고    scopus 로고
    • Newly synthesized dihydropyridine derivatives as modulators of P-glycoprotein-mediated multidrug resistance
    • Tanabe H, Tasaka S, Ohmori H, et al. Newly synthesized dihydropyridine derivatives as modulators of P-glycoprotein-mediated multidrug resistance. Bioorg Med Chem 6: 2219-2227, 1998.
    • (1998) Bioorg Med Chem , vol.6 , pp. 2219-2227
    • Tanabe, H.1    Tasaka, S.2    Ohmori, H.3
  • 30
    • 0033152176 scopus 로고    scopus 로고
    • Dipyridamole-mediated reversal of multidrug resistance in MRP overexpressing human lung carcinoma cells in vitro
    • Curtin NJ, Turner DP. Dipyridamole-mediated reversal of multidrug resistance in MRP overexpressing human lung carcinoma cells in vitro. Eur J Cancer 35: 1020-1026, 1999.
    • (1999) Eur J Cancer , vol.35 , pp. 1020-1026
    • Curtin, N.J.1    Turner, D.P.2
  • 32
    • 0031406294 scopus 로고    scopus 로고
    • Molecular modeling study of the multidrug resistance modifiers cis- and trans-flupentixol
    • Wiese M, Pajeva IK. Molecular modeling study of the multidrug resistance modifiers cis- and trans-flupentixol. Pharmazie 52: 679-685, 1997.
    • (1997) Pharmazie , vol.52 , pp. 679-685
    • Wiese, M.1    Pajeva, I.K.2
  • 33
    • 0032743612 scopus 로고    scopus 로고
    • Increase in doxorubicin cytotoxicity by carvedilol inhibition of P-glycoprotein activity
    • Jonsson O, Behnam-Motlagh P, Persson M, et al. Increase in doxorubicin cytotoxicity by carvedilol inhibition of P-glycoprotein activity. Biochem Pharmacol 58: 1801-1806, 1999.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1801-1806
    • Jonsson, O.1    Behnam-Motlagh, P.2    Persson, M.3
  • 34
    • 0031060647 scopus 로고    scopus 로고
    • Inhibition of drug transport by genistein
    • Castro AT, Altenberg GA. Inhibition of drug transport by genistein. Biochem Pharmacol 53: 89-93, 1997.
    • (1997) Biochem Pharmacol , vol.53 , pp. 89-93
    • Castro, A.T.1    Altenberg, G.A.2
  • 35
    • 0033390989 scopus 로고    scopus 로고
    • Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein
    • Sparreboom A, Planting AST, Jewell RC, et al. Clinical pharmacokinetics of doxorubicin in combination with GF120918, a potent inhibitor of MDR1 P-glycoprotein. Anticancer Drugs 10: 719-728, 1999.
    • (1999) Anticancer Drugs , vol.10 , pp. 719-728
    • Sparreboom, A.1    Planting, A.S.T.2    Jewell, R.C.3
  • 36
    • 0032492697 scopus 로고    scopus 로고
    • Synthesis and pharmacological activity of the stereoisomers of GP-88, a propafenone-type modulator of multidrug resistance
    • Chiba P, Rebitzer S, Richter E, et al. Synthesis and pharmacological activity of the stereoisomers of GP-88, a propafenone-type modulator of multidrug resistance. Bioorg Med Chem Lett 8: 829-832, 1998.
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 829-832
    • Chiba, P.1    Rebitzer, S.2    Richter, E.3
  • 37
    • 0032497591 scopus 로고    scopus 로고
    • Halogenated chalcones with high-affinity binding to P-glycoprotein
    • Bois F, Beney Ch, Boumendjel A, et al. Halogenated chalcones with high-affinity binding to P-glycoprotein. J Med Chem 41: 4161-4164, 1998.
    • (1998) J Med Chem , vol.41 , pp. 4161-4164
    • Bois, F.1    Beney, C.H.2    Boumendjel, A.3
  • 38
    • 0033590140 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein activity and chemosensitization of ovarian carcinoma 2780AD Cells by hexanoylglucosylceramide
    • Veldman RJ, Sietsma H, Klappe K, et al. Inhibition of P-glycoprotein activity and chemosensitization of ovarian carcinoma 2780AD Cells by hexanoylglucosylceramide. BBRC 266: 492-496, 1999.
    • (1999) BBRC , vol.266 , pp. 492-496
    • Veldman, R.J.1    Sietsma, H.2    Klappe, K.3
  • 39
    • 0031879970 scopus 로고    scopus 로고
    • IL-4 inhibits P-glycoprotein in normal and malignant NK cells
    • Tambur AR, Markham PN, Gebel HM. IL-4 inhibits P-glycoprotein in normal and malignant NK cells. Hum Immunol 59: 483-487, 1998.
    • (1998) Hum Immunol , vol.59 , pp. 483-487
    • Tambur, A.R.1    Markham, P.N.2    Gebel, H.M.3
  • 40
    • 0031635486 scopus 로고    scopus 로고
    • Development of novel reversal agents, imidazothiazole derivatives, targeting MDR1 and MRP-mediated multidrug resistance
    • Naito S, Koike K, Ono M, et al. Development of novel reversal agents, imidazothiazole derivatives, targeting MDR1 and MRP-mediated multidrug resistance. Oncol Res 10: 123-132, 1998.
    • (1998) Oncol Res , vol.10 , pp. 123-132
    • Naito, S.1    Koike, K.2    Ono, M.3
  • 41
    • 0032491227 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by aspidofractinine-type indole alkaloids
    • Kam T-S, Subramaniam G, Sim K-M, et al. Reversal of multidrug resistance by aspidofractinine-type indole alkaloids. Bioorg Med Chem Lett 8: 2769-2772, 1998.
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 2769-2772
    • Kam, T.-S.1    Subramaniam, G.2    Sim, K.-M.3
  • 42
    • 0033008034 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by kopsiflorine
    • Rho M-C, Toyoshima M, Hayasho M, et al. Reversal of multidrug resistance by kopsiflorine. Planta Med 65: 307-310, 1999.
    • (1999) Planta Med , vol.65 , pp. 307-310
    • Rho, M.-C.1    Toyoshima, M.2    Hayasho, M.3
  • 43
    • 0034834027 scopus 로고    scopus 로고
    • Reversal effects of antifungal drugs on multidrug resistance
    • Iida N, Takara K, Ohmoto N, et al. Reversal effects of antifungal drugs on multidrug resistance. Biol Pharm Bull 24: 1032-1036, 2001.
    • (2001) Biol Pharm Bull , vol.24 , pp. 1032-1036
    • Iida, N.1    Takara, K.2    Ohmoto, N.3
  • 44
    • 0031418812 scopus 로고    scopus 로고
    • Novel multidrug-resistance modulators, KR-30026 and KR-30031, in cancer cells
    • Choi SU, Lee BH, Kim KH, et al. Novel multidrug-resistance modulators, KR-30026 and KR-30031, in cancer cells. Anticancer Res 17: 4577-4582, 1997.
    • (1997) Anticancer Res , vol.17 , pp. 4577-4582
    • Choi, S.U.1    Lee, B.H.2    Kim, K.H.3
  • 45
    • 0032561298 scopus 로고    scopus 로고
    • L-Canavanine modulates cellular growth, chemosensitivity and P-glycoprotein substrate accumulation in cultured human cells
    • Worthen DR, Chien L, Tsuboi CP. L-Canavanine modulates cellular growth, chemosensitivity and P-glycoprotein substrate accumulation in cultured human cells. Cancer Lett 132: 229-239, 1998.
    • (1998) Cancer Lett , vol.132 , pp. 229-239
    • Worthen, D.R.1    Chien, L.2    Tsuboi, C.P.3
  • 46
    • 0032144087 scopus 로고    scopus 로고
    • Linear and cyclic peptides as substrates and modulators of P-glycoprotein: Peptide binding and effects on drug transport and accumulation
    • Sharom FJ, Lu P, Liu R. Linear and cyclic peptides as substrates and modulators of P-glycoprotein: peptide binding and effects on drug transport and accumulation. Biochem J 333: 621-630, 1998.
    • (1998) Biochem J , vol.333 , pp. 621-630
    • Sharom, F.J.1    Lu, P.2    Liu, R.3
  • 47
    • 0033530845 scopus 로고    scopus 로고
    • Reversal of resistance in multidrug resistant protein (MRP)-overexpressing cells by LY 329146
    • Norman BH, Dantzig AH, Kroin JS. Reversal of resistance in multidrug resistant protein (MRP)-overexpressing cells by LY329146. Bioorg Med Chem Lett 9: 3381-3386, 1999.
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 3381-3386
    • Norman, B.H.1    Dantzig, A.H.2    Kroin, J.S.3
  • 48
    • 0035030729 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by the P-glycoprotein modulator LY 335979, from the bench to the clinic
    • Dantzig AH, Law KL, Cao J. Reversal of multidrug resistance by the P-glycoprotein modulator LY335979, from the bench to the clinic. Curr Med Chem 8: 39-50, 2001.
    • (2001) Curr Med Chem , vol.8 , pp. 39-50
    • Dantzig, A.H.1    Law, K.L.2    Cao, J.3
  • 50
    • 0036202208 scopus 로고    scopus 로고
    • P-Glycoprotein inhibition by the multidrug resistance-reversing agent MS-209
    • Kimura Y, Aoki J, Kohno M, et al. P-Glycoprotein inhibition by the multidrug resistance-reversing agent MS-209. Cancer Chemother Pharmacol 49: 322-328, 2002.
    • (2002) Cancer Chemother Pharmacol , vol.49 , pp. 322-328
    • Kimura, Y.1    Aoki, J.2    Kohno, M.3
  • 51
    • 0035692758 scopus 로고    scopus 로고
    • Structure-activity relationship studies on the potent MDR modulator MM 36
    • Teodori E, Dei S, Garnier-Suillerot A, et al. Structure-activity relationship studies on the potent MDR modulator MM36. Med Chem Res 10: 563-576, 2001.
    • (2001) Med Chem Res , vol.10 , pp. 563-576
    • Teodori, E.1    Dei, S.2    Garnier-Suillerot, A.3
  • 52
    • 0034697265 scopus 로고    scopus 로고
    • Total synthesis of ningalin B and discovery of a new class of potent MDR reversal agents
    • Boger DL, Soenen DR, Boyce CW, et al. Total synthesis of ningalin B and discovery of a new class of potent MDR reversal agents. J Org Chem 65: 2479-2483, 2000.
    • (2000) J Org Chem , vol.65 , pp. 2479-2483
    • Boger, D.L.1    Soenen, D.R.2    Boyce, C.W.3
  • 53
    • 0031813770 scopus 로고    scopus 로고
    • Identification of the synthetic surfactant nonylphenol ethoxylate: A P-glycoprotein substrate in human urine
    • Charuk JHM, Grey AA, Reithmeier RAF. Identification of the synthetic surfactant nonylphenol ethoxylate: a P-glycoprotein substrate in human urine. Am J Physiol 274: F1127-F1139, 1999.
    • (1999) Am J Physiol , vol.274
    • Charuk, J.H.M.1    Grey, A.A.2    Reithmeier, R.A.F.3
  • 54
    • 0036011101 scopus 로고    scopus 로고
    • Pentoxifylline influences drug transport activity of P-glycoprotein and decreases mdr1 gene expression
    • Drobna Z, Stein U, Walther W, et al. Pentoxifylline influences drug transport activity of P-glycoprotein and decreases mdr1 gene expression. Gen Physiol Biophys 21: 103-109, 2000.
    • (2000) Gen Physiol Biophys , vol.21 , pp. 103-109
    • Drobna, Z.1    Stein, U.2    Walther, W.3
  • 55
    • 0034214366 scopus 로고    scopus 로고
    • Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance
    • Newman MJ, Rodarte JC, Benbatoul KD, et al. Discovery and characterization of OC144-093, a novel inhibitor of P-glycoprotein-mediated multidrug resistance. Cancer Res 60: 2964-2972, 2000.
    • (2000) Cancer Res , vol.60 , pp. 2964-2972
    • Newman, M.J.1    Rodarte, J.C.2    Benbatoul, K.D.3
  • 56
    • 0032739648 scopus 로고    scopus 로고
    • Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines
    • Vanhoefer U, Muller MR, Hilger RA, et al. Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines. Br J Cancer 81: 1304-1310, 1999.
    • (1999) Br J Cancer , vol.81 , pp. 1304-1310
    • Vanhoefer, U.1    Muller, M.R.2    Hilger, R.A.3
  • 57
    • 0035556313 scopus 로고    scopus 로고
    • Mechanism of senzitisation of MDR cancer cells by Pluronic block copolymers
    • Batrakova EV, Li S, Emquist WF, et al. Mechanism of senzitisation of MDR cancer cells by Pluronic block copolymers. Br J Cancer 85: 1987-1997, 2001.
    • (2001) Br J Cancer , vol.85 , pp. 1987-1997
    • Batrakova, E.V.1    Li, S.2    Emquist, W.F.3
  • 58
    • 0030898431 scopus 로고    scopus 로고
    • QSAR molecular modeling of catamphilic drugs able to modulate multidrug resistance in tumors
    • Pajeva IK, Wiese M. QSAR and molecular modeling of catamphilic drugs able to modulate multidrug resistance in tumors. Quant Struct Activity Relat 16: 1-10, 1997.
    • (1997) Quant Struct Activity Relat , vol.16 , pp. 1-10
    • Pajeva, I.K.1    Wiese, M.2
  • 60
    • 0030927574 scopus 로고    scopus 로고
    • Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles
    • de Verdiere AC, Dubernet C, Nemati F, et al. Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles. Br J Cancer 76: 198-205, 1997.
    • (1997) Br J Cancer , vol.76 , pp. 198-205
    • De Verdiere, A.C.1    Dubernet, C.2    Nemati, F.3
  • 61
    • 0034637475 scopus 로고    scopus 로고
    • The synthesis and evaluation of a solution phase indexed combinatorial library of non-natural polyenes for reversal of P-glycoprotein mediated MDR
    • Andrus MB, Turner TM, Sauna ZE, et al. The synthesis and evaluation of a solution phase indexed combinatorial library of non-natural polyenes for reversal of P-glycoprotein mediated MDR. J Org Chem 65: 4973-4983, 2000.
    • (2000) J Org Chem , vol.65 , pp. 4973-4983
    • Andrus, M.B.1    Turner, T.M.2    Sauna, Z.E.3
  • 62
    • 0032580718 scopus 로고    scopus 로고
    • Studies on propafenone-type modulators of multidrug resistance
    • Chiba P, Annibali D, Hitzler M, et al. Studies on propafenone-type modulators of multidrug resistance. II Farmaco 53: 357-364, 1998.
    • (1998) II Farmaco , vol.53 , pp. 357-364
    • Chiba, P.1    Annibali, D.2    Hitzler, M.3
  • 63
    • 0033557521 scopus 로고    scopus 로고
    • SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells
    • Cabot MC, Giuliano AE, Han T-Y, et al. SDZ PSC 833, the cyclosporine A analogue and multidrug resistance modulator activates ceramide synthesis and increases vinblastine sensitivity in drug-sensitive and drug-resistant cancer cells. Cancer Res 59: 880-885, 1999.
    • (1999) Cancer Res , vol.59 , pp. 880-885
    • Cabot, M.C.1    Giuliano, A.E.2    Han, T.-Y.3
  • 64
    • 0033567425 scopus 로고    scopus 로고
    • Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems and intact cells
    • Sharom FJ, Yu X, Lu P, et al. Interaction of the P-glycoprotein multidrug transporter (MDR1) with high affinity peptide chemosensitizers in isolated membranes, reconstituted systems and intact cells. Biochem Pharmacol 58: 571-586, 1999.
    • (1999) Biochem Pharmacol , vol.58 , pp. 571-586
    • Sharom, F.J.1    Yu, X.2    Lu, P.3
  • 65
    • 0033562673 scopus 로고    scopus 로고
    • IV protease inhibitor Ritonavir: A more potent inhibitor of P-glycoprotein than the cyclosporine analogue SDZ PSC 833
    • Drewe J, Gutman H, Fricker G, et al. IV protease inhibitor Ritonavir: a more potent inhibitor of P-glycoprotein than the cyclosporine analogue SDZ PSC 833. Biochem Pharmacol 57: 1147-1152, 1999.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1147-1152
    • Drewe, J.1    Gutman, H.2    Fricker, G.3
  • 66
    • 0032485361 scopus 로고    scopus 로고
    • Novel cellular determinants for reversal of multidrug resistance in cells expressing P170-glycoprotein
    • Yin M-B, Guo B, Voigt W, et al. Novel cellular determinants for reversal of multidrug resistance in cells expressing P170-glycoprotein. BBA 1401: 265-276, 1998.
    • (1998) BBA , vol.1401 , pp. 265-276
    • Yin, M.-B.1    Guo, B.2    Voigt, W.3
  • 67
    • 0032828093 scopus 로고    scopus 로고
    • Inhibition of P-glycoprotein activity and reversal of MDR in vitro by rosemary extract
    • Plouzek CA, Ciolino HP, Clarke R, et al. Inhibition of P-glycoprotein activity and reversal of MDR in vitro by rosemary extract. Eur J Cancer 35: 1541-1545, 1999.
    • (1999) Eur J Cancer , vol.35 , pp. 1541-1545
    • Plouzek, C.A.1    Ciolino, H.P.2    Clarke, R.3
  • 68
    • 17144450394 scopus 로고    scopus 로고
    • Phase I clinical and pharmacokinetic study of S9788: A new multidrug-resistance reversal agent
    • Tranchand B, Catimel G, Lucas C, et al. Phase I clinical and pharmacokinetic study of S9788: a new multidrug-resistance reversal agent. Cancer Chemother Pharmacol 41: 281-291, 1998.
    • (1998) Cancer Chemother Pharmacol , vol.41 , pp. 281-291
    • Tranchand, B.1    Catimel, G.2    Lucas, C.3
  • 69
    • 0035206547 scopus 로고    scopus 로고
    • Reversal of multidrug resistance by novel nitrophenyl pyrones SNF 4435C and D
    • Kurosawa K, Takahashi K, Tsuda E, et al. Reversal of multidrug resistance by novel nitrophenyl pyrones SNF4435C and D. Jpn J Cancer Res 92: 1235-1241, 2001.
    • (2001) Jpn J Cancer Res , vol.92 , pp. 1235-1241
    • Kurosawa, K.1    Takahashi, K.2    Tsuda, E.3
  • 70
    • 0031717670 scopus 로고    scopus 로고
    • Circumvention of P-glycoprotein-mediated multidrug resistance by S16020-2
    • Pierre A, Leonce S, Perez V, et al. Circumvention of P-glycoprotein-mediated multidrug resistance by S16020-2. Cancer Chemother Pharmacol 42: 454-460, 1998.
    • (1998) Cancer Chemother Pharmacol , vol.42 , pp. 454-460
    • Pierre, A.1    Leonce, S.2    Perez, V.3
  • 71
    • 0032479414 scopus 로고    scopus 로고
    • Reversal of MDR by the staurosporine derivatives CGP 41251 and CGP 42700
    • Utz I, Spitaler M, Rybczynska M, et al. Reversal of MDR by the staurosporine derivatives CGP 41251 and CGP 42700. Int J Cancer 77: 64-69, 1998.
    • (1998) Int J Cancer , vol.77 , pp. 64-69
    • Utz, I.1    Spitaler, M.2    Rybczynska, M.3
  • 72
    • 0030656565 scopus 로고    scopus 로고
    • Multidrug-resistance modulators from stephania japonica
    • Hall AM, Chang C-J. Multidrug-resistance modulators from stephania japonica. J Nat Prod 60: 1193-1195, 1997.
    • (1997) J Nat Prod , vol.60 , pp. 1193-1195
    • Hall, A.M.1    Chang, C.-J.2
  • 73
    • 0032548461 scopus 로고    scopus 로고
    • New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells
    • Ojima I, Bounaud P-Y, Takeuchi C, et al. New taxanes as highly efficient reversal agents for multidrug resistance in cancer cells. Bioorg Med Chem Lett 8: 189-194, 1998.
    • (1998) Bioorg Med Chem Lett , vol.8 , pp. 189-194
    • Ojima, I.1    Bounaud, P.-Y.2    Takeuchi, C.3
  • 74
    • 0031851582 scopus 로고    scopus 로고
    • Syntheses of Taxuspine C derivatives as functional inhibitors of P-glycoprotein
    • Sako M, Suzuki H, Hirota K. Syntheses of Taxuspine C derivatives as functional inhibitors of P-glycoprotein. Chem Pharm Bull (Tokyo) 46: 1135-1139, 1998.
    • (1998) Chem Pharm Bull (Tokyo) , vol.46 , pp. 1135-1139
    • Sako, M.1    Suzuki, H.2    Hirota, K.3
  • 75
    • 0036275206 scopus 로고    scopus 로고
    • Function and mechanism of pyronaradine: A new inhibitor of P-glycoprotein
    • Qi J, Yang C-Z, Wang C-Y, et al. Function and mechanism of pyronaradine: a new inhibitor of P-glycoprotein. Acta Pharmacol Sin 23: 544-550, 2002.
    • (2002) Acta Pharmacol Sin , vol.23 , pp. 544-550
    • Qi, J.1    Yang, C.-Z.2    Wang, C.-Y.3
  • 76
    • 0031773482 scopus 로고    scopus 로고
    • In vitro and in vivo reversal of cancer cell multidrug resistance by the semi-synthetic antibiotic Tiamulin
    • Baggetto LG, Dong M, Bernaud J, et al. In vitro and in vivo reversal of cancer cell multidrug resistance by the semi-synthetic antibiotic Tiamulin. Biochem Pharmacol 56: 1219-1228, 1998.
    • (1998) Biochem Pharmacol , vol.56 , pp. 1219-1228
    • Baggetto, L.G.1    Dong, M.2    Bernaud, J.3
  • 77
    • 0031859909 scopus 로고    scopus 로고
    • Torilin, a sesquiterpene from Torilis japonica, reverses MDR in cancer cells
    • Kim SE, Kim YH, Kim YC, et al. Torilin, a sesquiterpene from Torilis japonica, reverses MDR in cancer cells. Planta Med 64: 332-334, 1998.
    • (1998) Planta Med , vol.64 , pp. 332-334
    • Kim, S.E.1    Kim, Y.H.2    Kim, Y.C.3
  • 78
    • 16744363513 scopus 로고    scopus 로고
    • Overcoming of multidrug resistance by VA-033, a novel derivative of aponvincaminic acid ester
    • Nanaumi K, Tsuchida K, Nakaike S, et al. Overcoming of multidrug resistance by VA-033, a novel derivative of aponvincaminic acid ester. Eur J Pharmacol 327: 239-246, 1997.
    • (1997) Eur J Pharmacol , vol.327 , pp. 239-246
    • Nanaumi, K.1    Tsuchida, K.2    Nakaike, S.3
  • 80
    • 0037196568 scopus 로고    scopus 로고
    • Inhibition of the multidrug resistance P-glycoproein activity by green tea polypenols
    • Jodoin J, Demeule M, Beliveau R. Inhibition of the multidrug resistance P-glycoproein activity by green tea polypenols. BBA 1542: 149-159, 2000.
    • (2000) BBA , vol.1542 , pp. 149-159
    • Jodoin, J.1    Demeule, M.2    Beliveau, R.3
  • 81
    • 12444318333 scopus 로고    scopus 로고
    • Studies on quinazolinones as dual inhibitors of Pgp and MRP 1 in multiple resistance
    • Wang S, Ryder H, Pretswell H, et al. Studies on quinazolinones as dual inhibitors of Pgp and MRP1 in multiple resistance. Bioorg Med Chem Lett 12: 571-574, 2000.
    • (2000) Bioorg Med Chem Lett , vol.12 , pp. 571-574
    • Wang, S.1    Ryder, H.2    Pretswell, H.3
  • 82
    • 0037030690 scopus 로고    scopus 로고
    • Reversal of multidrug resistance of mouse lymphoma cells by a new, natural jatropane diterpenoid
    • Hohman J, Molnar J, Redei D, et al. Reversal of multidrug resistance of mouse lymphoma cells by a new, natural jatropane diterpenoid. J Med Chem 45: 2425-2431, 2002.
    • (2002) J Med Chem , vol.45 , pp. 2425-2431
    • Hohman, J.1    Molnar, J.2    Redei, D.3
  • 83
    • 0033593855 scopus 로고    scopus 로고
    • Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives
    • Roe M, Folkes A, Ashworth P, et al. Reversal of P-glycoprotein mediated multidrug resistance by novel anthranilamide derivatives. Bioorg Med Chem Lett. 9: 595-600, 1999.
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 595-600
    • Roe, M.1    Folkes, A.2    Ashworth, P.3
  • 84
    • 0035863315 scopus 로고    scopus 로고
    • In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR 9576
    • Mistry P, Stewart AJ, Dangerfield W, et al. In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576. Cancer Ras 61: 749-675, 2001.
    • (2001) Cancer Ras , vol.61 , pp. 749-675
    • Mistry, P.1    Stewart, A.J.2    Dangerfield, W.3
  • 85
    • 0032547344 scopus 로고    scopus 로고
    • Outwitting drug resistance requires researchers to take many tacks
    • Reynolds T. Outwitting drug resistance requires researchers to take many tacks. J Natl Cancer Inst 90: 1186-1188, 1998.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1186-1188
    • Reynolds, T.1
  • 86
    • 0343437984 scopus 로고    scopus 로고
    • Cisplatin resistance in ovarian cancer: Mismatch repair and engagement of apoptosis
    • Hickman JA, Dive C, eds. Totowa, NJ: Humana Press
    • Brown R. Cisplatin resistance in ovarian cancer: mismatch repair and engagement of apoptosis. In: Hickman JA, Dive C, eds. Apoptosis and Chemosensitivity. Totowa, NJ: Humana Press. 69-86, 1999.
    • (1999) Apoptosis and Chemosensitivity , pp. 69-86
    • Brown, R.1
  • 87
    • 0035233825 scopus 로고    scopus 로고
    • Intracellular P-glycoprotein in multidrug resistant tumor cells
    • Arancia G, Molinari A, Calcabrini A, et al. Intracellular P-glycoprotein in multidrug resistant tumor cells. Ital J Anat Embryol 106: 59-68, 2001.
    • (2001) Ital J Anat Embryol , vol.106 , pp. 59-68
    • Arancia, G.1    Molinari, A.2    Calcabrini, A.3
  • 88
    • 0033761664 scopus 로고    scopus 로고
    • Thermal dependence of multidrug-resistant modulator efficiency
    • Castaign M, Loiseau A, Dani M. Thermal dependence of multidrug-resistant modulator efficiency. J Pharm Pharmacol 52: 1171-1178, 2000.
    • (2000) J Pharm Pharmacol , vol.52 , pp. 1171-1178
    • Castaign, M.1    Loiseau, A.2    Dani, M.3
  • 89
    • 0032957644 scopus 로고    scopus 로고
    • Influence of cell concentration in limiting the therapeutic benefit of P-glycoprotein reversal agents
    • Tunggal JK, Ballinger JR, Tannock IF. Influence of cell concentration in limiting the therapeutic benefit of P-glycoprotein reversal agents. Int J Cancer 81: 741-747, 1999.
    • (1999) Int J Cancer , vol.81 , pp. 741-747
    • Tunggal, J.K.1    Ballinger, J.R.2    Tannock, I.F.3
  • 90
    • 0032862993 scopus 로고    scopus 로고
    • The human MDR P-glycoprotein is inactive when its maturation is inhibited
    • Loo TW, Clarke DM. The human MDR P-glycoprotein is inactive when its maturation is inhibited. FASEB J 13: 1724-1732, 1999.
    • (1999) FASEB J , vol.13 , pp. 1724-1732
    • Loo, T.W.1    Clarke, D.M.2
  • 91
    • 0033730691 scopus 로고    scopus 로고
    • Role of human CYP3A and P-glycoprotein in the adsorbtion of drugs
    • van de Waterbeemd H. Role of human CYP3A and P-glycoprotein in the adsorbtion of drugs. Eur J Pharm Sci 12: 1, 2000.
    • (2000) Eur J Pharm Sci , vol.12 , pp. 1
    • Van de Waterbeemd, H.1
  • 92
    • 0032840591 scopus 로고    scopus 로고
    • The major vault protein (MVP), a new multidrug resistance associated protein
    • Rimsza LM, Campbell K, Dalton WS, et al. The major vault protein (MVP), a new multidrug resistance associated protein. Leuk Lymphoma 34: 315-324, 1999.
    • (1999) Leuk Lymphoma , vol.34 , pp. 315-324
    • Rimsza, L.M.1    Campbell, K.2    Dalton, W.S.3
  • 93
    • 0037005953 scopus 로고    scopus 로고
    • Is there less resistance on the chemoresistance front?
    • Miller M. Is there less resistance on the chemoresistance front? JNCI 94: 15-16, 2002.
    • (2002) JNCI , vol.94 , pp. 15-16
    • Miller, M.1
  • 94
    • 0036229852 scopus 로고    scopus 로고
    • Drugs as P-glycoprotein substrates, inhibitors and inducers
    • Kim RB. Drugs as P-glycoprotein substrates, inhibitors and inducers. Drug Metab Rev 34: 47-54, 2002.
    • (2002) Drug Metab Rev , vol.34 , pp. 47-54
    • Kim, R.B.1
  • 95
    • 0036131991 scopus 로고    scopus 로고
    • Overcoming drug resistance: Targeting more than one site
    • Karp JE, Mookerjee BP. Overcoming drug resistance: targeting more than one site. Leuk Res 26: 107-109, 2002.
    • (2002) Leuk Res , vol.26 , pp. 107-109
    • Karp, J.E.1    Mookerjee, B.P.2


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