-
1
-
-
0030004763
-
Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein
-
DOI 10.1016/0925-4439(96)00008-7
-
S. Ayesh, Y.M. Shao, and W.D. Stein Co-operative, competitive and non-competitive interactions between modulators of P-glycoprotein Biochim. Biophys. Acta 1316 1996 8 18 (Pubitemid 26174919)
-
(1996)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1316
, Issue.1
, pp. 8-18
-
-
Ayesh, S.1
Shao, Y.-M.2
Stein, W.D.3
-
2
-
-
33344474213
-
Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: In vitro and in vivo assessments
-
DOI 10.1124/dmd.105.007757
-
M. Ballent, A. Lifschitz, G. Virkel, J. Sallovitz, and C. Lanusse Modulation of the P-glycoprotein-mediated intestinal secretion of ivermectin: in vitro and in vivo assessments Drug Metab. Dispos. 34 2006 457 463 (Pubitemid 43290904)
-
(2006)
Drug Metabolism and Disposition
, vol.34
, Issue.3
, pp. 457-463
-
-
Ballent, M.1
Lifschitz, A.2
Virkel, G.3
Sallovitz, J.4
Lanusse, C.5
-
3
-
-
70349826431
-
Understanding the causes of multidrug resistance in cancer: A comparison of doxorubicin and sunitinib
-
H.J. Broxterman, K.J. Gotink, and H.M. Verheul Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib Drug Resist. Updat. 12 2009 114 126
-
(2009)
Drug Resist. Updat.
, vol.12
, pp. 114-126
-
-
Broxterman, H.J.1
Gotink, K.J.2
Verheul, H.M.3
-
4
-
-
80053471265
-
P-glycoprotein inhibition: The past, the present and the future
-
R.A. Darby, R. Callaghan, and R.M. McMahon P-glycoprotein inhibition: the past, the present and the future Curr. Drug Metab. 12 2011 722 731
-
(2011)
Curr. Drug Metab.
, vol.12
, pp. 722-731
-
-
Darby, R.A.1
Callaghan, R.2
McMahon, R.M.3
-
5
-
-
84857427753
-
Xanthines down-regulate the drug transporter ABCG2 and reverse multidrug resistance
-
R. Ding, J. Shi, K. Pabon, and K.W. Scotto Xanthines down-regulate the drug transporter ABCG2 and reverse multidrug resistance Mol. Pharmacol. 81 2012 328 337
-
(2012)
Mol. Pharmacol.
, vol.81
, pp. 328-337
-
-
Ding, R.1
Shi, J.2
Pabon, K.3
Scotto, K.W.4
-
6
-
-
34447124425
-
Multidrug resistance proteins do not predict benefit of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program
-
DOI 10.1158/1078-0432.CCR-06-2446
-
M. Filipits, V. Haddad, K. Schmid, A. Huynh, A. Dunant, F. Andre, E. Brambilla, R. Stahel, J.P. Pignon, J.C. Soria, H.H. Popper, T. Le Chevalier, and R. Pirker Multidrug resistance proteins do not predict benefit of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: international adjuvant lung cancer trial biologic program Clin. Cancer Res. 13 2007 3892 3898 (Pubitemid 47037596)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.13
, pp. 3892-3898
-
-
Filipits, M.1
Haddad, V.2
Schmid, K.3
Huynh, A.4
Dunant, A.5
Andre, F.6
Brambilla, E.7
Stahel, R.8
Pignon, J.-P.9
Soria, J.-C.10
Popper, H.H.11
Le Chevalier, T.12
Pirker, R.13
-
7
-
-
84859032184
-
Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays
-
S. Forster, A.E. Thumser, S.R. Hood, and N. Plant Characterization of rhodamine-123 as a tracer dye for use in in vitro drug transport assays PloS One 7 2012 e33253
-
(2012)
PloS One
, vol.7
, pp. 33253
-
-
Forster, S.1
Thumser, A.E.2
Hood, S.R.3
Plant, N.4
-
8
-
-
0038813942
-
Modulation of P-glycoprotein (PGP) mediated multidrug resistance (MDR) using chemosensitizers: Recent advances in the design of selective MDR modulators
-
R. Krishna, and L.D. Mayer Modulation of P-glycoprotein (PGP) mediated multidrug resistance (MDR) using chemosensitizers: recent advances in the design of selective MDR modulators Curr. Med. Chem. Anticancer Agents 1 2001 163 174
-
(2001)
Curr. Med. Chem. Anticancer Agents
, vol.1
, pp. 163-174
-
-
Krishna, R.1
Mayer, L.D.2
-
9
-
-
33745756680
-
MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance
-
H. Lage MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance Curr. Drug Targets 7 2006 813 821
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 813-821
-
-
Lage, H.1
-
10
-
-
53849096994
-
An overview of cancer multidrug resistance: A still unsolved problem
-
H. Lage An overview of cancer multidrug resistance: a still unsolved problem Cell. Mol. Life Sci. 65 2008 3145 3167
-
(2008)
Cell. Mol. Life Sci.
, vol.65
, pp. 3145-3167
-
-
Lage, H.1
-
11
-
-
79960675115
-
Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters
-
I.V. Lebedeva, P. Pande, and W.F. Patton Sensitive and specific fluorescent probes for functional analysis of the three major types of mammalian ABC transporters PloS One 6 2011 e22429
-
(2011)
PloS One
, vol.6
, pp. 22429
-
-
Lebedeva, I.V.1
Pande, P.2
Patton, W.F.3
-
12
-
-
79952802131
-
The third-generation P-glycoprotein inhibitor tariquidar may overcome bacterial multidrug resistance by increasing intracellular drug concentration
-
I. Leitner, J. Nemeth, T. Feurstein, A. Abrahim, P. Matzneller, H. Lagler, T. Erker, O. Langer, and M. Zeitlinger The third-generation P-glycoprotein inhibitor tariquidar may overcome bacterial multidrug resistance by increasing intracellular drug concentration J. Antimicrob. Chemother. 66 2011 834 839
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, pp. 834-839
-
-
Leitner, I.1
Nemeth, J.2
Feurstein, T.3
Abrahim, A.4
Matzneller, P.5
Lagler, H.6
Erker, T.7
Langer, O.8
Zeitlinger, M.9
-
13
-
-
0037113961
-
Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein
-
DOI 10.1074/jbc.M208433200
-
T.W. Loo, and D.M. Clarke Location of the rhodamine-binding site in the human multidrug resistance P-glycoprotein J. Biol. Chem. 277 2002 44332 44338 (Pubitemid 36157868)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.46
, pp. 44332-44338
-
-
Loo, T.W.1
Clarke, D.M.2
-
14
-
-
12144262818
-
Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site
-
DOI 10.1021/bi0485326
-
M.R. Lugo, and F.J. Sharom Interaction of LDS-751 with P-glycoprotein and mapping of the location of the R drug binding site Biochemistry 44 2005 643 655 (Pubitemid 40105495)
-
(2005)
Biochemistry
, vol.44
, Issue.2
, pp. 643-655
-
-
Lugo, M.R.1
Sharom, F.J.2
-
15
-
-
0033862765
-
Communication between multiple drug binding sites on P-glycoprotein
-
C. Martin, G. Berridge, C.F. Higgins, P. Mistry, P. Charlton, and R. Callaghan Communication between multiple drug binding sites on P-glycoprotein Mol. Pharmacol. 58 2000 624 632
-
(2000)
Mol. Pharmacol.
, vol.58
, pp. 624-632
-
-
Martin, C.1
Berridge, G.2
Higgins, C.F.3
Mistry, P.4
Charlton, P.5
Callaghan, R.6
-
17
-
-
33745746815
-
Pharmacological strategies for overcoming multidrug resistance
-
S. Nobili, I. Landini, B. Giglioni, and E. Mini Pharmacological strategies for overcoming multidrug resistance Curr. Drug Targets 7 2006 861 879
-
(2006)
Curr. Drug Targets
, vol.7
, pp. 861-879
-
-
Nobili, S.1
Landini, I.2
Giglioni, B.3
Mini, E.4
-
18
-
-
84860535245
-
Three decades of P-gp inhibitors: Skimming through several generations and scaffolds
-
A. Palmeira, E. Sousa, M.H. Vasconcelos, and M.M. Pinto Three decades of P-gp inhibitors: skimming through several generations and scaffolds Curr. Med. Chem. 19 2012 1946 2025
-
(2012)
Curr. Med. Chem.
, vol.19
, pp. 1946-2025
-
-
Palmeira, A.1
Sousa, E.2
Vasconcelos, M.H.3
Pinto, M.M.4
-
19
-
-
79952173594
-
Selective TRAIL-triggered apoptosis due to overexpression of TRAIL death receptor 5 (DR5) in P-glycoprotein-bearing multidrug resistant CEM/VBL1000 human leukemia cells
-
S.J. Park, K. Bijangi-Vishehsaraei, and A.R. Safa Selective TRAIL-triggered apoptosis due to overexpression of TRAIL death receptor 5 (DR5) in P-glycoprotein-bearing multidrug resistant CEM/VBL1000 human leukemia cells Int. J. Biochem. Mol. Biol. 1 2010 90 100
-
(2010)
Int. J. Biochem. Mol. Biol.
, vol.1
, pp. 90-100
-
-
Park, S.J.1
Bijangi-Vishehsaraei, K.2
Safa, A.R.3
-
20
-
-
8444241197
-
Reversal of P-glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells
-
DOI 10.1038/sj.cgt.7700738
-
Z. Peng, Z. Xiao, Y. Wang, P. Liu, Y. Cai, S. Lu, W. Feng, and Z.C. Han Reversal of P-glycoprotein-mediated multidrug resistance with small interference RNA (siRNA) in leukemia cells Cancer Gene Ther. 11 2004 707 712 (Pubitemid 39488468)
-
(2004)
Cancer Gene Therapy
, vol.11
, Issue.11
, pp. 707-712
-
-
Peng, Z.1
Xiao, Z.2
Wang, Y.3
Liu, P.4
Cai, Y.5
Lu, S.6
Feng, W.7
Han, Z.C.8
-
21
-
-
33645805657
-
In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: A recommendation for probe substrates
-
J. Rautio, J.E. Humphreys, L.O. Webster, A. Balakrishnan, J.P. Keogh, J.R. Kunta, C.J. Serabjit-Singh, and J.W. Polli In vitro p-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates Drug Metab. Dispos. 34 2006 786 792
-
(2006)
Drug Metab. Dispos.
, vol.34
, pp. 786-792
-
-
Rautio, J.1
Humphreys, J.E.2
Webster, L.O.3
Balakrishnan, A.4
Keogh, J.P.5
Kunta, J.R.6
Serabjit-Singh, C.J.7
Polli, J.W.8
-
23
-
-
0030782511
-
Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities
-
A.B. Shapiro, and V. Ling Positively cooperative sites for drug transport by P-glycoprotein with distinct drug specificities Eur. J. Biochem./FEBS 250 1997 130 137 (Pubitemid 27504592)
-
(1997)
European Journal of Biochemistry
, vol.250
, Issue.1
, pp. 130-137
-
-
Shapiro, A.B.1
Ling, V.2
-
24
-
-
0032130787
-
The mechanism of ATP-dependent multidrug transport by P-glycoprotein
-
A.B. Shapiro, and V. Ling The mechanism of ATP-dependent multidrug transport by P-glycoprotein Acta Physiol. Scand. Suppl. 643 1998 227 234 (Pubitemid 28439422)
-
(1998)
Acta Physiologica Scandinavica, Supplement
, vol.163
, Issue.643
, pp. 227-234
-
-
Shapiro, A.B.1
Ling, V.2
-
25
-
-
80053297774
-
A novel indirubin derivative PHII-7 potentiates adriamycin cytotoxicity via inhibiting P-glycoprotein expression in human breast cancer MCF-7/ADR cells
-
R. Shi, W. Li, X. Zhang, Y. Zhang, H. Peng, Y. Xie, D. Fan, R. Liu, X. Liu, and D. Xiong A novel indirubin derivative PHII-7 potentiates adriamycin cytotoxicity via inhibiting P-glycoprotein expression in human breast cancer MCF-7/ADR cells Eur. J. Pharmacol. 669 2011 38 44
-
(2011)
Eur. J. Pharmacol.
, vol.669
, pp. 38-44
-
-
Shi, R.1
Li, W.2
Zhang, X.3
Zhang, Y.4
Peng, H.5
Xie, Y.6
Fan, D.7
Liu, R.8
Liu, X.9
Xiong, D.10
-
26
-
-
0036798452
-
P-glycoprotein as a therapeutic target: Good news
-
A.A. Shtil P-glycoprotein as a therapeutic target: good news Leukemia 16 2002 2169 2170
-
(2002)
Leukemia
, vol.16
, pp. 2169-2170
-
-
Shtil, A.A.1
-
27
-
-
55749106727
-
Effect of HZ08, a novel modulator of tumor multidrug-resistance, on adriamycin pharmacokinetics in rats
-
F. Yan, W.R. Fang, J. Cen, T.J. Hang, and Y.M. Li Effect of HZ08, a novel modulator of tumor multidrug-resistance, on adriamycin pharmacokinetics in rats Chin. J. New Drugs 39 2008 447 452
-
(2008)
Chin. J. New Drugs
, vol.39
, pp. 447-452
-
-
Yan, F.1
Fang, W.R.2
Cen, J.3
Hang, T.J.4
Li, Y.M.5
-
28
-
-
45749103718
-
Reversal of P-glycoprotein and multidrug resistance-associated protein 1 mediated multidrug resistance in cancer cells by HZ08 isomers, tetrataisohydroquinolin derivatives
-
DOI 10.1248/bpb.31.1258
-
F. Yan, Y. Jiang, Y.M. Li, X. Zhen, J. Cen, and W.R. Fang Reversal of P-glycoprotein and multidrug resistance-associated protein 1 mediated multidrug resistance in cancer cells by HZ08 Isomers, tetrataisohydroquinolin derivatives Biol. Pharmaceut. Bull. 31 2008 1258 1264 (Pubitemid 351871172)
-
(2008)
Biological and Pharmaceutical Bulletin
, vol.31
, Issue.6
, pp. 1258-1264
-
-
Yan, F.1
Jiang, Y.2
Li, Y.-M.3
Zhen, X.4
Cen, J.5
Fang, W.-R.6
-
29
-
-
77952312245
-
Recent advances in the research of P-glycoprotein inhibitors
-
K. Yang, J. Wu, and X. Li Recent advances in the research of P-glycoprotein inhibitors Biosci. Trends 2 2008 137 146
-
(2008)
Biosci. Trends
, vol.2
, pp. 137-146
-
-
Yang, K.1
Wu, J.2
Li, X.3
|