메뉴 건너뛰기




Volumn 1, Issue 2, 2010, Pages 257-272

Antinuclear antibodies with nucleosome-restricted specificity for targeted delivery of chemotherapeutic agents

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTINUCLEAR ANTIBODY; CAMPTOTHECIN DERIVATIVE; DOXORUBICIN; FENRETINIDE; LIPOSOME; MACROGOL; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 2C5; NANOCARRIER; NUCLEOSOME AUTOANTIBODY; PACLITAXEL; PHOSPHATIDYLETHANOLAMINE; PLATINUM COMPLEX; POLYMER; TETRAKIS(4 SULFOPHENYL)PORPHINE; TRASTUZUMAB; UNCLASSIFIED DRUG; VINCRISTINE;

EID: 79955009083     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.10.30     Document Type: Review
Times cited : (15)

References (150)
  • 1
    • 65649127261 scopus 로고    scopus 로고
    • Engineered affinity proteins for tumour-targeting applications
    • Friedman M, Stahl S. Engineered affinity proteins for tumour-targeting applications. Biotechnol. Appl. Biochem. 53(Pt 1), 1-29 (2009).
    • (2009) Biotechnol. Appl. Biochem. , vol.53 , Issue.PART 1 , pp. 1-29
    • Friedman, M.1    Stahl, S.2
  • 3
    • 18244362593 scopus 로고    scopus 로고
    • Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates
    • DOI 10.1158/1078-0432.CCR-04-2517
    • Allen TM, Mumbengegwi DR, Charrois GJ. Anti-CD19-targeted liposomal doxorubicin improves the therapeutic efficacy in murine B-cell lymphoma and ameliorates the toxicity of liposomes with varying drug release rates. Clin. Cancer Res. 11(9), 3567-3573 (2005). (Pubitemid 40627913)
    • (2005) Clinical Cancer Research , vol.11 , Issue.9 , pp. 3567-3573
    • Allen, T.M.1    Mumbengegwi, D.R.2    Charrois, G.J.R.3
  • 4
    • 0035866799 scopus 로고    scopus 로고
    • Liposome-encapsulated doxorubicin targeted to CD44: A strategy to kill CD44-overexpressing tumor cells
    • Eliaz RE, Szoka FC Jr. Liposome-encapsulated doxorubicin targeted to CD44: a strategy to kill CD44-overexpressing tumor cells. Cancer Res. 61(6), 2592-2601 (2001). (Pubitemid 32685844)
    • (2001) Cancer Research , vol.61 , Issue.6 , pp. 2592-2601
    • Eliaz, R.E.1    Szoka Jr., F.C.2
  • 5
    • 24644437854 scopus 로고    scopus 로고
    • Ligand-targeted liposomes for cancer treatment
    • DOI 10.2174/156720105774370159
    • Sapra P, Tyagi P, Allen TM. Ligand-targeted liposomes for cancer treatment. Curr. Drug Deliv. 2(4), 369-381 (2005). (Pubitemid 41277769)
    • (2005) Current Drug Delivery , vol.2 , Issue.4 , pp. 369-381
    • Sapra, P.1    Tyagi, P.2    Allen, T.M.3
  • 6
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • DOI 10.1038/nrd1632
    • Torchilin VP. Recent advances with liposomes as pharmaceutical carriers. Nat. Rev. Drug Discov. 4(2), 145-160 (2005). (Pubitemid 40282557)
    • (2005) Nature Reviews Drug Discovery , vol.4 , Issue.2 , pp. 145-160
    • Torchilin, V.P.1
  • 7
  • 8
    • 11144300731 scopus 로고    scopus 로고
    • Future directions of liposome- and immunoliposome-based cancer therapeutics
    • DOI 10.1053/j.seminoncol.2004.08.009, PII S0093775404003860
    • Park JW, Benz CC, Martin FJ. Future directions of liposome- and immunoliposome-based cancer therapeutics. Semin. Oncol. 31(6 Suppl. 13), 196-205 (2004). (Pubitemid 40023249)
    • (2004) Seminars in Oncology , vol.31 , Issue.SUPPL. 13 , pp. 196-205
    • Park, J.W.1    Benz, C.C.2    Martin, F.J.3
  • 9
    • 0038797831 scopus 로고    scopus 로고
    • Ligand-targeted liposomal anticancer drugs
    • DOI 10.1016/S0163-7827(03)00032-8
    • Sapra P, Allen TM. Ligand-targeted liposomal anticancer drugs. Prog. Lipid Res. 42(5), 439-462 (2003). (Pubitemid 36700404)
    • (2003) Progress in Lipid Research , vol.42 , Issue.5 , pp. 439-462
    • Sapra, P.1    Allen, T.M.2
  • 11
    • 39749160560 scopus 로고    scopus 로고
    • Antibody-targeted liposomes in cancer therapy and imaging
    • DOI 10.1517/17425247.5.2.189
    • Sofou S, Sgouros G. Antibody-targeted liposomes in cancer therapy and imaging. Expert Opin. Drug Deliv. 5(2), 189-204 (2008). (Pubitemid 351308311)
    • (2008) Expert Opinion on Drug Delivery , vol.5 , Issue.2 , pp. 189-204
    • Sofou, S.1    Sgouros, G.2
  • 12
    • 0018803497 scopus 로고
    • Preservation of antimyosin antibody activity after covalent coupling to liposomes
    • Torchilin VP, Khaw BA, Smirnov VN, Haber E. Preservation of antimyosin antibody activity after covalent coupling to liposomes. Biochem. Biophys. Res. Commun. 89(4), 1114-1119 (1979).
    • (1979) Biochem. Biophys. Res. Commun. , vol.89 , Issue.4 , pp. 1114-1119
    • Torchilin, V.P.1    Khaw, B.A.2    Smirnov, V.N.3    Haber, E.4
  • 13
    • 0022543710 scopus 로고
    • A new hydrophobic anchor for the attachment of proteins to liposomal membranes
    • DOI 10.1016/0014-5793(86)80654-8
    • Weissig V, Lasch J, Klibanov AL, Torchilin VP. A new hydrophobic anchor for the attachment of proteins to liposomal membranes. FEBS Lett. 202(1), 86-90 (1986). (Pubitemid 16051133)
    • (1986) FEBS Letters , vol.202 , Issue.1 , pp. 86-90
    • Weissig, V.1    Lasch, J.2    Klibanov, A.L.3    Torchilin, V.P.4
  • 14
    • 0023944896 scopus 로고
    • Protein immobilization on the surface of liposomes via carbodiimide activation in the presence of
    • Bogdanov AA Jr, Klibanov AL, Torchilin VP. Protein immobilization on the surface of liposomes via carbodiimide activation in the presence of N-hydroxysulfosuccinimide. FEBS Lett. 231(2), 381-384 (1988).
    • (1988) N-hydroxysulfosuccinimide. FEBS Lett. , vol.231 , Issue.2 , pp. 381-384
    • Bogdanov Jr., A.A.1    Klibanov, A.L.2    Torchilin, V.P.3
  • 17
    • 0025934384 scopus 로고
    • Carboxyacyl derivatives of cardiolipin as four-tailed hydrophobic anchors for the covalent coupling of hydrophilic proteins to liposomes
    • Niedermann G, Weissig V, Sternberg B, Lasch J. Carboxyacyl derivatives of cardiolipin as four-tailed hydrophobic anchors for the covalent coupling of hydrophilic proteins to liposomes. Biochim. Biophys. Acta 1070(2), 401-408 (1991).
    • (1991) Biochim. Biophys. Acta , vol.1070 , Issue.2 , pp. 401-408
    • Niedermann, G.1    Weissig, V.2    Sternberg, B.3    Lasch, J.4
  • 20
    • 0029120094 scopus 로고
    • A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells
    • Allen TM, Brandeis E, Hansen CB, Kao GY, Zalipsky S. A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells. Biochim. Biophys. Acta 1237(2), 99-108 (1995).
    • (1995) Biochim. Biophys. Acta , vol.1237 , Issue.2 , pp. 99-108
    • Allen, T.M.1    Brandeis, E.2    Hansen, C.B.3    Kao, G.Y.4    Zalipsky, S.5
  • 21
    • 0032496677 scopus 로고    scopus 로고
    • Receptor versus non-receptor mediated clearance of liposomes
    • DOI 10.1016/S0169-409X(97)00133-6, PII S0169409X97001336
    • Kamps JA, Scherphof GL. Receptor versus nonreceptor mediated clearance of liposomes. Adv. Drug Deliv. Rev. 32(1-2), 81-97 (1998). (Pubitemid 28277177)
    • (1998) Advanced Drug Delivery Reviews , vol.32 , Issue.1-2 , pp. 81-97
    • Scherphof, G.L.1    Kamps, J.A.A.M.2
  • 22
    • 0030728258 scopus 로고    scopus 로고
    • Systemic therapy with 3BIT, a triple combination cocktail of anti-CD19, -CD22, and -CD38-saporin immunotoxins, is curative of human B-cell lymphoma in severe combined immunodeficient mice
    • Flavell DJ, Noss A, Pulford KA, Ling N, Flavell SU. Systemic therapy with 3bit, a triple combination cocktail of anti-CD19, -CD22 and -CD38-saporin immunotoxins, is curative of human B-cell lymphoma in severe combined immunodeficient mice. Cancer Res. 57(21), 4824-4829 (1997). (Pubitemid 27468990)
    • (1997) Cancer Research , vol.57 , Issue.21 , pp. 4824-4829
    • Flavell, D.J.1    Noss, A.2    Pulford, K.A.F.3    Ling, N.4    Flavell, S.U.5
  • 23
    • 0030876540 scopus 로고    scopus 로고
    • Immunoliposomes bearing polyethyleneglycol-coupled Fab' fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo
    • DOI 10.1016/S0014-5793(97)00905-8, PII S0014579397009058
    • Maruyama K, Takahashi N, Tagawa T, Nagaike K, Iwatsuru M. Immunoliposomes bearing polyethyleneglycol-coupled FAb' fragment show prolonged circulation time and high extravasation into targeted solid tumors in vivo. FEBS Lett. 413(1), 177-180 (1997). (Pubitemid 27348659)
    • (1997) FEBS Letters , vol.413 , Issue.1 , pp. 177-180
    • Maruyama, K.1    Takahashi, N.2    Tagawa, T.3    Nagaike, K.4    Iwatsuru, M.5
  • 25
    • 0035575846 scopus 로고    scopus 로고
    • Targeting Stealth liposomes in a murine model of human small cell lung cancer
    • DOI 10.1016/S0005-2736(01)00411-4, PII S0005273601004114
    • Moreira JN, Gaspar R, Allen TM. Targeting stealth liposomes in a murine model of human small cell lung cancer. Biochim. Biophys. Acta 1515(2), 167-176 (2001). (Pubitemid 33086833)
    • (2001) Biochimica et Biophysica Acta - Biomembranes , vol.1515 , Issue.2 , pp. 167-176
    • Moreira, J.N.1    Gaspar, R.2    Allen, T.M.3
  • 27
    • 33746172167 scopus 로고    scopus 로고
    • Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models
    • DOI 10.1158/0008-5472.CAN-05-4199
    • Kirpotin DB, Drummond DC, Shao Y et al. Antibody targeting of long-circulating lipidic nanoparticles does not increase tumor localization but does increase internalization in animal models. Cancer Res. 66(13), 6732-6740 (2006). (Pubitemid 44085631)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6732-6740
    • Kirpotin, D.B.1    Drummond, D.C.2    Shao, Y.3    Shalaby, M.R.4    Hong, K.5    Nielsen, U.B.6    Marks, J.D.7    Benz, C.C.8    Park, J.W.9
  • 28
    • 1842478453 scopus 로고    scopus 로고
    • Improved outcome when b-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the cd19 and cd20 epitopes
    • DOI 10.1158/1078-0432.CCR-03-0376
    • Sapra P, Allen TM. Improved outcome when B-cell lymphoma is treated with combinations of immunoliposomal anticancer drugs targeted to both the CD19 and CD20 epitopes. Clin. Cancer Res. 10(7), 2530-2537 (2004). (Pubitemid 38445715)
    • (2004) Clinical Cancer Research , vol.10 , Issue.7 , pp. 2530-2537
    • Sapra, P.1    Allen, T.M.2
  • 31
    • 0001160175 scopus 로고    scopus 로고
    • In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma
    • Lopes de Menezes DE, Pilarski LM, Allen TM. In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma. Cancer Res. 58(15), 3320-3330 (1998). (Pubitemid 28371072)
    • (1998) Cancer Research , vol.58 , Issue.15 , pp. 3320-3330
    • Lopes De Menezes, D.E.1    Pilarski, L.M.2    Allen, T.M.3
  • 32
    • 0038105280 scopus 로고    scopus 로고
    • 2 immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma
    • DOI 10.1016/S0304-3835(03)00099-5
    • Brignole C, Marimpietri D, Gambini C, Allen TM, Ponzoni M, Pastorino F. Development of FAb' fragments of anti-Gd2 immunoliposomes entrapping doxorubicin for experimental therapy of human neuroblastoma. Cancer Lett. 197(1-2), 199-204 (2003). (Pubitemid 36860011)
    • (2003) Cancer Letters , vol.197 , Issue.1-2 , pp. 199-204
    • Brignole, C.1    Marimpietri, D.2    Gambini, C.3    Allen, T.M.4    Ponzoni, M.5    Pastorino, F.6
  • 33
    • 0037224431 scopus 로고    scopus 로고
    • Doxorubicin-loaded Fab′ fragments of anti-disialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice
    • Pastorino F, Brignole C, Marimpietri D et al. doxorubicin-loaded FAb fragments of antidisialoganglioside immunoliposomes selectively inhibit the growth and dissemination of human neuroblastoma in nude mice. Cancer Res. 63(1), 86-92 (2003). (Pubitemid 36070424)
    • (2003) Cancer Research , vol.63 , Issue.1 , pp. 86-92
    • Pastorino, F.1    Brignole, C.2    Marimpietri, D.3    Sapra, P.4    Moase, E.H.5    Allen, T.M.6    Ponzoni, M.7
  • 37
    • 29244489232 scopus 로고    scopus 로고
    • Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo
    • DOI 10.1158/0008-5472.CAN-05-1093
    • Mamot C, Drummond DC, Noble CO et al. Epidermal growth factor receptor-targeted immunoliposomes significantly enhance the efficacy of multiple anticancer drugs in vivo. Cancer Res. 65(24), 11631-11638 (2005). (Pubitemid 41821723)
    • (2005) Cancer Research , vol.65 , Issue.24 , pp. 11631-11638
    • Mamot, C.1    Drummond, D.C.2    Noble, C.O.3    Kallab, V.4    Guo, Z.5    Hong, K.6    Kirpotin, D.B.7    Park, J.W.8
  • 38
    • 33745284972 scopus 로고    scopus 로고
    • EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells
    • Mamot C, Ritschard R, Kung W, Park JW, Herrmann R, Rochlitz CF. EGFR-targeted immunoliposomes derived from the monoclonal antibody EMD72000 mediate specific and efficient drug delivery to a variety of colorectal cancer cells. J. Drug Target. 14(4), 215-223 (2006).
    • (2006) J. Drug Target. , vol.14 , Issue.4 , pp. 215-223
    • Mamot, C.1    Ritschard, R.2    Kung, W.3    Park, J.W.4    Herrmann, R.5    Rochlitz, C.F.6
  • 39
    • 34247607115 scopus 로고    scopus 로고
    • Construction of anti-EGFR immunoliposomes via folate-folate binding protein affinity
    • DOI 10.1016/j.ijpharm.2006.12.007, PII S0378517306010647
    • Pan X, Lee RJ. Construction of anti-EGFR immunoliposomes via folate-folate binding protein affinity. Int. J. Pharm. 336(2), 276-283 (2007). (Pubitemid 46670654)
    • (2007) International Journal of Pharmaceutics , vol.336 , Issue.2 , pp. 276-283
    • Pan, X.1    Lee, R.J.2
  • 40
    • 33846434809 scopus 로고    scopus 로고
    • Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR
    • DOI 10.1021/bc060174r
    • Pan X, Wu G, Yang W, Barth RF, Tjarks W, Lee RJ. Synthesis of cetuximab-immunoliposomes via a cholesterol-based membrane anchor for targeting of EGFR. Bioconjug. Chem. 18(1), 101-108 (2007). (Pubitemid 46145999)
    • (2007) Bioconjugate Chemistry , vol.18 , Issue.1 , pp. 101-108
    • Pan, X.1    Wu, G.2    Yang, W.3    Barth, R.F.4    Tjarks, W.5    Lee, R.J.6
  • 41
    • 0034671316 scopus 로고    scopus 로고
    • Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice
    • Sugano M, Egilmez NK, Yokota SJ et al. Antibody targeting of doxorubicin-loaded liposomes suppresses the growth and metastatic spread of established human lung tumor xenografts in severe combined immunodeficient mice. Cancer Res. 60(24), 6942-6949 (2000). (Pubitemid 32059167)
    • (2000) Cancer Research , vol.60 , Issue.24 , pp. 6942-6949
    • Sugano, M.1    Egilmez, N.K.2    Yokota, S.J.3    Chen, F.-A.4    Harding, J.5    Huang, S.K.6    Bankert, R.B.7
  • 43
    • 36749016236 scopus 로고    scopus 로고
    • Antitumor activity of an epithelial cell adhesion molecule-targeted nanovesicular drug delivery system
    • DOI 10.1158/1535-7163.MCT-07-0615
    • Hussain S, Pluckthun A, Allen TM, Zangemeister-Wittke U. Anti-tumor activity of an epithelial cell adhesion molecule targeted nanovesicular drug delivery system. Mol. Cancer. Ther. 6(11), 3019-3027 (2007). (Pubitemid 350206780)
    • (2007) Molecular Cancer Therapeutics , vol.6 , Issue.11 , pp. 3019-3027
    • Hussain, S.1    Pluckthun, A.2    Allen, T.M.3    Zangemeister-Wittke, U.4
  • 44
    • 16644380590 scopus 로고    scopus 로고
    • Cytotoxic tumor targeting with scFv antibody-modified liposomes
    • Marty C, Schwendener RA. Cytotoxic tumor targeting with scFv antibody-modified liposomes. Methods Mol. Med. 109, 389-402 (2005).
    • (2005) Methods Mol. Med. , vol.109 , pp. 389-402
    • Marty, C.1    Schwendener, R.A.2
  • 45
    • 18744427000 scopus 로고    scopus 로고
    • Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105)
    • DOI 10.1016/j.bbamem.2004.03.007, PII S0005273604000859
    • Volkel T, Holig P, Merdan T, Muller R, Kontermann RE. Targeting of immunoliposomes to endothelial cells using a single-chain Fv fragment directed against human endoglin (CD105). Biochim. Biophys. Acta 1663(1-2), 158-166 (2004). (Pubitemid 38625590)
    • (2004) Biochimica et Biophysica Acta - Biomembranes , vol.1663 , Issue.1-2 , pp. 158-166
    • Volkel, T.1    Holig, P.2    Merdan, T.3    Muller, R.4    Kontermann, R.E.5
  • 46
    • 38349122223 scopus 로고    scopus 로고
    • Targeting to tumor necrotic regions with biotinylated antibody and streptavidin modified liposomes
    • Pan H, Han L, Chen W, Yao M, Lu W. Targeting to tumor necrotic regions with biotinylated antibody and streptavidin modified liposomes. J. Control. Release 125(3), 228-235 (2008).
    • (2008) J. Control. Release , vol.125 , Issue.3 , pp. 228-235
    • Pan, H.1    Han, L.2    Chen, W.3    Yao, M.4    Lu, W.5
  • 48
    • 0029091892 scopus 로고
    • Anti-nuclear autoantibodies of the aged reactive against the surface of tumor but not normal cells
    • Iakoubov L, Rokhlin O, Torchilin V. Anti-nuclear autoantibodies of the aged reactive against the surface of tumor but not normal cells. Immunol. Lett. 47(1-2), 147-149 (1995).
    • (1995) Immunol. Lett. , vol.47 , Issue.1-2 , pp. 147-149
    • Iakoubov, L.1    Rokhlin, O.2    Torchilin, V.3
  • 49
    • 54249095971 scopus 로고
    • Monoclonal anti-nuclear autoantibody from the aged effectively suppresses tumor development
    • Iakoubov L, Mongayt D, Torchilin VP. Monoclonal anti-nuclear autoantibody from the aged effectively suppresses tumor development in vivo. Cancer Biother. Radiopharm. 8, 299-310 (1995).
    • (1995) Cancer Biother. Radiopharm. , vol.8 , pp. 299-310
    • Iakoubov, L.1    Mongayt, D.2    Torchilin, V.P.3
  • 50
    • 0031308829 scopus 로고    scopus 로고
    • A novel class of antitumor antibodies: Nucleosome-restricted antinuclear autoantibodies (ana) from healthy aged nonautoimmune mice
    • Iakoubov LZ, Torchilin VP. A novel class of antitumor antibodies: nucleosome-restricted antinuclear autoantibodies (ANA) from healthy aged nonautoimmune mice. Oncol. Res. 9(8), 439-446 (1997). (Pubitemid 127825997)
    • (1997) Oncology Research , vol.9 , Issue.8 , pp. 439-446
    • Lakoubov, L.Z.1    Torchilin, V.P.2
  • 52
    • 0019413824 scopus 로고
    • Organ-specific IgM autoantibodies to liver, heart and brain in man: Generalized occurrence and possible functional significance in normal individuals, and studies in patients with multiple sclerosis
    • Daar AS, Fabre JW. Organ-specific IgM autoantibodies to liver, heart and brain in man: generalized occurrence and possible functional significance in normal individuals and studies in patients with multiple sclerosis. Clin. Exp. Immunol. 45(1), 37-47 (1981). (Pubitemid 11072440)
    • (1981) Clinical and Experimental Immunology , vol.45 , Issue.1 , pp. 37-47
    • Daar, A.S.1    Fabre, J.W.2
  • 54
    • 0025905663 scopus 로고
    • Natural autoantibodies: From horror autotoxicus' to gnothi seauton'
    • Avrameas S. Natural autoantibodies: from horror autotoxicus' to gnothi seauton'. Immunol. Today 12(5), 154-159 (1991).
    • (1991) Immunol. Today , vol.12 , Issue.5 , pp. 154-159
    • Avrameas, S.1
  • 55
    • 0022786539 scopus 로고
    • Ontogenetic changes in the spectrum of specificities of natural monoclonal autoantibodies reacting with nerve tissue antigens
    • Sakharova AV, Iakubov LZ, Grivennikov IA, Romanova NV, Lobazina N. [Ontogenetic changes in the spectrum of specificities of natural monoclonal autoantibodies reacting with nerve tissue antigens]. Zh. Obshch. Biol. 47(5), 625-630 (1986).
    • (1986) Zh. Obshch. Biol. , vol.47 , Issue.5 , pp. 625-630
    • Sakharova, A.V.1    Iakubov, L.Z.2    Grivennikov, I.A.3    Romanova, N.V.4    Lobazina, N.5
  • 56
    • 0028917208 scopus 로고
    • Antinuclear antibodies in healthy aging people: A prospective study
    • Xavier RM, Yamauchi Y, Nakamura M et al. Antinuclear antibodies in healthy aging people: a prospective study. Mech. Ageing Dev. 78(2), 145-154 (1995).
    • (1995) Mech. Ageing Dev. , vol.78 , Issue.2 , pp. 145-154
    • Xavier, R.M.1    Yamauchi, Y.2    Nakamura, M.3
  • 57
    • 0016269860 scopus 로고
    • Immunologic theory of aging: Current status
    • Walford RL. Immunologic theory of aging: current status. Fed. Proc. 33(9), 2020-2027 (1974).
    • (1974) Fed. Proc. , vol.33 , Issue.9 , pp. 2020-2027
    • Walford, R.L.1
  • 59
    • 0017072189 scopus 로고
    • Natural antibodies directed against murine lymphosarcoma cells: Variability of level in individual mice
    • Pierotti MA, Colnaghi MI. Natural antibodies directed against murine lymphosarcoma cells: variability of level in individual mice. Int. J. Cancer 18(2), 223-229 (1976).
    • (1976) Int. J. Cancer , vol.18 , Issue.2 , pp. 223-229
    • Pierotti, M.A.1    Colnaghi, M.I.2
  • 60
    • 0016590770 scopus 로고
    • Anti-tumour antibodies in normal mouse sera
    • Martin SE, Martin WJ. Anti-tumour antibodies in normal mouse sera. Int. J. Cancer 15(4), 658-664 (1975).
    • (1975) Int. J. Cancer , vol.15 , Issue.4 , pp. 658-664
    • Martin, S.E.1    Martin, W.J.2
  • 61
    • 0019519629 scopus 로고
    • Murine natural anti-tumor antibodies. II. The contribution of natural antibodies to tumor surveillance
    • DOI 10.1002/ijc.2910270407
    • Chow DA, Wolosin LB, Greenberg AH. Murine natural anti-tumor antibodies. II. The contribution of natural antibodies to tumor surveillance. Int. J. Cancer 27(4), 459-469 (1981). (Pubitemid 11159731)
    • (1981) International Journal of Cancer , vol.27 , Issue.4 , pp. 459-469
    • Chow, D.A.1    Wolosin, L.B.2    Greenberg, A.H.3
  • 62
    • 0026497207 scopus 로고
    • Immune senescence: Mechanisms and clinical implications
    • Ben-Yehuda A, Weksler ME. Immune senescence: mechanisms and clinical implications. Cancer Invest. 10(6), 525-531 (1992).
    • (1992) Cancer Invest. , vol.10 , Issue.6 , pp. 525-531
    • Ben-Yehuda, A.1    Weksler, M.E.2
  • 63
    • 0014201363 scopus 로고
    • Serum anti-g-globulin and antinuclear factors in the aged
    • Cammarata RJ, Rodnan GP, Fennell RH. Serum anti-g-globulin and antinuclear factors in the aged. JAMA 199(7), 455-458 (1967).
    • (1967) JAMA , vol.199 , Issue.7 , pp. 455-458
    • Cammarata, R.J.1    Rodnan, G.P.2    Fennell, R.H.3
  • 64
    • 0015821513 scopus 로고
    • Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans
    • Hallgren HM, Buckley CE 3rd, Gilbertsen VA, Yunis EJ. Lymphocyte phytohemagglutinin responsiveness, immunoglobulins and autoantibodies in aging humans. J. Immunol. 111(4), 1101-1107 (1973).
    • (1973) J. Immunol. , vol.111 , Issue.4 , pp. 1101-1107
    • Hallgren, H.M.1    Buckley III, C.E.2    Gilbertsen, V.A.3    Yunis, E.J.4
  • 65
    • 0017064709 scopus 로고
    • Antinuclear factors in sera from healthy blood donors
    • Wiik A. Antinuclear factors in sera from healthy blood donors. Acta Pathol. Microbiol. Scand. C 84(3), 215-220 (1976).
    • (1976) Acta Pathol. Microbiol. Scand. C , vol.84 , Issue.3 , pp. 215-220
    • Wiik, A.1
  • 67
    • 0023585724 scopus 로고
    • ADCC in aging rats with methylcholanthrene-induced sarcoma (MC-SA)
    • Ziolkowska M, Nowak JJ, Ryzewska A. ADCC in aging rats with methylcholanthrene-induced sarcoma (MC-SA). Arch. Immunol. Ther. Exp. 35(6), 853-862 (1987).
    • (1987) Arch. Immunol. Ther. Exp. , vol.35 , Issue.6 , pp. 853-862
    • Ziolkowska, M.1    Nowak, J.J.2    Ryzewska, A.3
  • 68
    • 0017672842 scopus 로고
    • Certain polyclonal antinuclear antibodies cross-react with the surface membrane of human lymphocytes and granulocytes
    • Rekvig OP, Hannestad K. Certain polyclonal antinuclear antibodies cross-react with the surface membrane of human lymphocytes and granulocytes. Scand. J. Immunol. 6(10), 1041-1054 (1977). (Pubitemid 8198285)
    • (1977) Scandinavian Journal of Immunology , vol.6 , Issue.10 , pp. 1041-1054
    • Rekvig, O.P.1    Hannestad, K.2
  • 69
    • 0027503065 scopus 로고
    • Anti-histone autoantibodies react specifically with the B cell surface
    • Mecheri S, Dannecker G, Dennig D, Poncet P, Hoffmann MK. Anti-histone autoantibodies react specifically with the B cell surface. Mol. Immunol. 30(6), 549-557 (1993).
    • (1993) Mol. Immunol. , vol.30 , Issue.6 , pp. 549-557
    • Mecheri, S.1    Dannecker, G.2    Dennig, D.3    Poncet, P.4    Hoffmann, M.K.5
  • 71
    • 0031823158 scopus 로고    scopus 로고
    • Nucleosome-releasing treatment makes surviving tumor cells better targets for nucleosome-specific anticancer antibodies
    • DOI 10.1046/j.1525-1500.1998.00055.x
    • Iakoubov LZ, Torchilin VP. Nucleosome-releasing treatment makes surviving tumor cells better targets for nucleosome-specific anticancer antibodies. Cancer Detect. Prev. 22(5), 470-475 (1998). (Pubitemid 28395565)
    • (1998) Cancer Detection and Prevention , vol.22 , Issue.5 , pp. 470-475
    • Iakoubov, L.Z.1    Torchilin, V.P.2
  • 72
    • 84934877344 scopus 로고    scopus 로고
    • Structure and function of histone H2AX
    • Pinto DM, Flaus A. Structure and function of histone H2AX. Subcell. Biochem. 50, 55-78 (2010).
    • (2010) Subcell. Biochem. , vol.50 , pp. 55-78
    • Pinto, D.M.1    Flaus, A.2
  • 73
    • 0842324785 scopus 로고    scopus 로고
    • The nucleosome: From genomic organization to genomic regulation
    • DOI 10.1016/S0092-8674(04)00044-3
    • Khorasanizadeh S. The nucleosome: from genomic organization to genomic regulation. Cell 116(2), 259-272 (2004). (Pubitemid 38167316)
    • (2004) Cell , vol.116 , Issue.2 , pp. 259-272
    • Khorasanizadeh, S.1
  • 74
    • 0032144071 scopus 로고    scopus 로고
    • Histones and nucleosomes in Archaea and Eukarya: A comparative analysis
    • DOI 10.1007/s007920050053
    • Pereira SL, Reeve JN. Histones and nucleosomes in archaea and eukarya: a comparative analysis. Extremophiles 2(3), 141-148 (1998). (Pubitemid 28407992)
    • (1998) Extremophiles , vol.2 , Issue.3 , pp. 141-148
    • Pereira, S.L.1    Reeve, J.N.2
  • 75
    • 0026942571 scopus 로고
    • Anti-DNA antibodies and their relationships with antihistone and antinucleosome specificities
    • Jacob L, Viard JP. Anti-DNA antibodies and their relationships with antihistone and antinucleosome specificities. Eur. J. Med. 1(7), 425-431 (1992).
    • (1992) Eur. J. Med. , vol.1 , Issue.7 , pp. 425-431
    • Jacob, L.1    Viard, J.P.2
  • 76
    • 0030023407 scopus 로고    scopus 로고
    • Binding of nucleosomes to a cell surface receptor: Redistribution and endocytosis in the presence of lupus antibodies
    • DOI 10.1002/eji.1830260230
    • Koutouzov S, Cabrespines A, Amoura Z, Chabre H, Lotton C, Bach JF. Binding of nucleosomes to a cell surface receptor: redistribution and endocytosis in the presence of lupus antibodies. Eur. J. Immunol. 26(2), 472-486 (1996). (Pubitemid 26060258)
    • (1996) European Journal of Immunology , vol.26 , Issue.2 , pp. 472-486
    • Koutouzov, S.1    Cabrespines, A.2    Amoura, Z.3    Chabre, H.4    Lotton, C.5    Bach, J.-F.6
  • 77
    • 0035873090 scopus 로고    scopus 로고
    • Calreticulin, a potential cell surface receptor involved in cell penetration of anti-DNA antibodies
    • Seddiki N, Nato F, Lafaye P, Amoura Z, Piette JC, Mazie JC. Calreticulin, a potential cell surface receptor involved in cell penetration of anti-DNA antibodies. J. Immunol. 166(10), 6423-6429 (2001). (Pubitemid 32440777)
    • (2001) Journal of Immunology , vol.166 , Issue.10 , pp. 6423-6429
    • Seddiki, N.1    Nato, F.2    Lafaye, P.3    Amoura, Z.4    Piette, J.C.5    Mazie, J.C.6
  • 78
    • 0026508030 scopus 로고
    • Regulation of nuclear antigen expression on the cell surface of human monocytes
    • Emlen W, Holers VM, Arend WP, Kotzin B. Regulation of nuclear antigen expression on the cell surface of human monocytes. J. Immunol. 148(10), 3042-3048 (1992).
    • (1992) J. Immunol. , vol.148 , Issue.10 , pp. 3042-3048
    • Emlen, W.1    Holers, V.M.2    Arend, W.P.3    Kotzin, B.4
  • 79
    • 0025991586 scopus 로고
    • The spontaneous apoptotic cell death of normal human lymphocytes in vitro: The release of, and immunoproliferative response to, nucleosomes
    • Bell DA, Morrison B. The spontaneous apoptotic cell death of normal human lymphocytes in vitro: the release of, and immunoproliferative response to, nucleosomes in vitro. Clin. Immunol. Immunopathol. 60(1), 13-26 (1991).
    • (1991) Clin. Immunol. Immunopathol. , vol.60 , Issue.1 , pp. 13-26
    • Bell, D.A.1    Morrison, B.2
  • 84
    • 0027479796 scopus 로고
    • Apoptosis (The 1992 Frank Rose Memorial Lecture)
    • Wyllie AH. Apoptosis (the 1992 Frank Rose memorial lecture). Br. J. Cancer 67(2), 205-208 (1993). (Pubitemid 23049537)
    • (1993) British Journal of Cancer , vol.67 , Issue.2 , pp. 205-208
    • Wyllie, A.H.1
  • 85
    • 0028330345 scopus 로고
    • Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus
    • Emlen W, Niebur J, Kadera R. Accelerated in vitro apoptosis of lymphocytes from patients with systemic lupus erythematosus. J. Immunol. 152(7), 3685-3692 (1994). (Pubitemid 24098067)
    • (1994) Journal of Immunology , vol.152 , Issue.7 , pp. 3685-3692
    • Emlen, W.1    Niebur, J.2    Kadera, R.3
  • 86
    • 0034966564 scopus 로고    scopus 로고
    • Plasma levels of nucleosomes and nucleosome-autoantibody complexes in murine lupus: Effects of disease progression and lipopolysaccharide administration
    • Licht R, van Bruggen MC, Oppers-Walgreen B, Rijke TP, Berden JH. Plasma levels of nucleosomes and nucleosome-autoantibody complexes in murine lupus: effects of disease progression and lipopolyssacharide administration. Arthritis Rheum. 44(6), 1320-1330 (2001). (Pubitemid 32537530)
    • (2001) Arthritis and Rheumatism , vol.44 , Issue.6 , pp. 1320-1330
    • Licht, R.1    Van Bruggen, M.C.J.2    Oppers-Walgreen, B.3    Rijke, T.P.M.4    Berden, J.H.M.5
  • 88
    • 1242311596 scopus 로고    scopus 로고
    • What can we learn from herceptin trials in metastatic breast cancer?
    • Bell R. What can we learn from herceptin trials in metastatic breast cancer? Oncology 63(Suppl. 1), 39-46 (2002).
    • (2002) Oncology , vol.63 , Issue.SUPPL. 1 , pp. 39-46
    • Bell, R.1
  • 89
    • 0037819344 scopus 로고    scopus 로고
    • An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab
    • DOI 10.1093/annonc/mdg175
    • Boye J, Elter T, Engert A. An overview of the current clinical use of the anti-CD20 monoclonal antibody rituximab. Ann. Oncol. 14(4), 520-535 (2003). (Pubitemid 41295078)
    • (2003) Annals of Oncology , vol.14 , Issue.4 , pp. 520-535
    • Boye, J.1    Elter, T.2    Engert, A.3
  • 90
    • 0038290555 scopus 로고    scopus 로고
    • Antibody-mediated EGF receptor blockade as an anticancer therapy: From the laboratory to the clinic
    • Mendelsohn J. Antibody-mediated EGF receptor blockade as an anticancer therapy: from the laboratory to the clinic. Cancer Immunol. Immunother. 52(5), 342-346 (2003). (Pubitemid 36578028)
    • (2003) Cancer Immunology, Immunotherapy , vol.52 , Issue.5 , pp. 342-346
    • Mendelsohn, J.1
  • 91
    • 0037397622 scopus 로고    scopus 로고
    • A clinical and scientific overview of tositumomab and iodine I 131 tositumomab
    • Zelenetz AD. A clinical and scientific overview of tositumomab and iodine I 131 tositumomab. Semin. Oncol. 30(2 Suppl. 4), 22-30 (2003). (Pubitemid 36505464)
    • (2003) Seminars in Oncology , vol.30 , Issue.2 SUPPL. 4 , pp. 22-30
    • Zelenetz, A.D.1
  • 92
    • 0020073813 scopus 로고
    • Heterogeneity of the natural humoral anti-tumor immune response in mice as shown by monoclonal antibodies
    • Colnaghi MI, Menard S, Tagliabue E, Torre GD. Heterogeneity of the natural humoral anti-tumor immune response in mice as shown by monoclonal antibodies. J. Immunol. 128(6), 2757-2762 (1982). (Pubitemid 12124512)
    • (1982) Journal of Immunology , vol.128 , Issue.6 , pp. 2757-2762
    • Colnaghi, M.I.1    Menard, S.2    Tagliabue, E.3    Della Torre, G.4
  • 94
    • 18544404283 scopus 로고    scopus 로고
    • Natural IgM Antibodies and Immunosurveillance Mechanisms against Epithelial Cancer Cells in Humans
    • Brandlein S, Pohle T, Ruoff N, Wozniak E, Muller-Hermelink HK, Vollmers HP. Natural IgM antibodies and immunosurveillance mechanisms against epithelial cancer cells in humans. Cancer Res. 63(22), 7995-8005 (2003). (Pubitemid 37466738)
    • (2003) Cancer Research , vol.63 , Issue.22 , pp. 7995-8005
    • Brandlein, S.1    Pohle, T.2    Ruoff, N.3    Wozniak, E.4    Muller-Hermelink, H.-K.5    Vollmers, H.P.6
  • 95
    • 0035424853 scopus 로고    scopus 로고
    • Antinuclear autoantibodies as potential antineoplastic agents
    • DOI 10.1016/S1471-4906(01)01984-6, PII S1471490601019846
    • Torchilin VP, Iakoubov LZ, Estrov Z. Antinuclear autoantibodies as potential antineoplastic agents. Trends Immunol. 22(8), 424-427 (2001). (Pubitemid 32709975)
    • (2001) Trends in Immunology , vol.22 , Issue.8 , pp. 424-427
    • Torchilin, V.P.1    Iakoubov, L.Z.2    Estrov, Z.3
  • 96
    • 0025282645 scopus 로고
    • Anti-DNA antibodies and lupus nephritis: The complexity of crossreactivity
    • Brinkman K, Termaat R, Berden JH, Smeenk RJ. Anti-DNA antibodies and lupus nephritis: the complexity of crossreactivity. Immunol. Today 11(7), 232-234 (1990). (Pubitemid 20198986)
    • (1990) Immunology Today , vol.11 , Issue.7 , pp. 232-234
    • Brinkman, K.1    Termaat, R.2    Berden, J.H.M.3    Smeenk, R.J.T.4
  • 97
    • 0020620077 scopus 로고
    • Monoclonal antibody against a differentiation antigen on human leukemia cells: Cross-reactivity with rat leukemia and suppression of rat leukemia in vivo
    • Johnson RJ, Shin HS. Monoclonal antibody against a differentiation antigen on human leukemia cells: cross-reactivity with rat leukemia and suppression of rat leukemia in vivo. J. Immunol. 130(6), 2930-2936 (1983). (Pubitemid 13107734)
    • (1983) Journal of Immunology , vol.130 , Issue.6 , pp. 2930-2936
    • Johnson, R.J.1    Shin, H.S.2
  • 98
    • 0025086361 scopus 로고
    • A cytotoxic monoclonal anti-leukemia antibody binds to histone H1
    • Sorace JM, Johnson RJ. A cytotoxic monoclonal anti-leukemia antibody binds to histone H1. Hybridoma 9(5), 419-427 (1990). (Pubitemid 20378323)
    • (1990) Hybridoma , vol.9 , Issue.5 , pp. 419-427
    • Sorace, J.M.1    Johnson, R.J.2
  • 99
    • 1542777180 scopus 로고    scopus 로고
    • Therapeutic potential of antinuclear autoantibodies in cancer
    • Torchilin VP, Iakoubov LZ, Estrov Z. Therapeutic potential of antinuclear autoantibodies in cancer. J. Cancer Ther. 1, 179-190 (2003).
    • (2003) J. Cancer Ther. , vol.1 , pp. 179-190
    • Torchilin, V.P.1    Iakoubov, L.Z.2    Estrov, Z.3
  • 100
    • 0021334108 scopus 로고
    • Lysosomal enzyme release from polymorphonuclear leukocytes induced by immune complexes of IgM and of IgG
    • Lucisano YM, Mantovani B. Lysosomal enzyme release from polymorphonuclear leukocytes induced by immune complexes of IgM and of IgG. J. Immunol. 132(4), 2015-2020 (1984). (Pubitemid 14166676)
    • (1984) Journal of Immunology , vol.132 , Issue.4 , pp. 2015-2020
    • Lucisano, Y.M.1    Mantovani, B.2
  • 101
    • 0037061453 scopus 로고    scopus 로고
    • Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
    • DOI 10.1038/416603a
    • Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416(6881), 603-607 (2002). (Pubitemid 34406754)
    • (2002) Nature , vol.416 , Issue.6881 , pp. 603-607
    • Leadbetter, E.A.1    Rifkin, I.R.2    Hohlbaum, A.M.3    Beaudette, B.C.4    Shlomchik, M.J.5    Marshak-Rothstein, A.6
  • 103
    • 0031047805 scopus 로고    scopus 로고
    • Nucleosome-dependent escape of tumor cells from natural-killer-mediated lysis: Nucleosomes are taken up by target cells and act at a postconjugation level
    • DOI 10.1007/s002620050342
    • Le Lann-Terrisse AD, Fournie GJ, Benoist H. Nucleosome-dependent escape of tumor cells from natural-killer-mediated lysis: nucleosomes are taken up by target cells and act at a postconjugation level. Cancer Immunol. Immunother. 43(6), 337-344 (1997). (Pubitemid 27102219)
    • (1997) Cancer Immunology Immunotherapy , vol.43 , Issue.6 , pp. 337-344
    • Le Lann-Terrisse, A.-D.1    Fournie, G.J.2    Benoist, H.3
  • 104
    • 0033981030 scopus 로고    scopus 로고
    • Antineural and antinuclear autoantibodies are of prognostic relevance in non- small cell lung cancer
    • DOI 10.1016/S0003-4975(99)01198-4, PII S0003497599011984
    • Blaes F, Klotz M, Huwer H et al. Antineural and antinuclear autoantibodies are of prognostic relevance in nonsmall cell lung cancer. Ann. Thorac. Surg. 69(1), 254-258 (2000). (Pubitemid 30078859)
    • (2000) Annals of Thoracic Surgery , vol.69 , Issue.1 , pp. 254-258
    • Blaes, F.1    Klotz, M.2    Huwer, H.3    Straub, U.4    Kalweit, G.5    Schimrigk, K.6    Schafers, H.-J.7
  • 106
    • 0029099045 scopus 로고
    • Immune-mediated and unusual complications during interferon-a therapy in chronic myelogenous leukemia
    • Sacchi S, Kantarjian H, O'Brien S, Cohen PR, Pierce S, Talpaz M. Immune-mediated and unusual complications during interferon-a therapy in chronic myelogenous leukemia. J. Clin. Oncol. 13(9), 2401-2407 (1995).
    • (1995) J. Clin. Oncol. , vol.13 , Issue.9 , pp. 2401-2407
    • Sacchi, S.1    Kantarjian, H.2    O'brien, S.3    Cohen, P.R.4    Pierce, S.5    Talpaz, M.6
  • 108
    • 28044458581 scopus 로고    scopus 로고
    • Monoclonal antibody 2C5-mediated binding of liposomes to brain tumor cells in vitro and in subcutaneous tumor model in vivo
    • DOI 10.1080/10611860500286239
    • Gupta B, Levchenko TS, Mongayt DA, Torchilin VP. Monoclonal antibody 2C5-mediated binding of liposomes to brain tumor cells in vitro and in subcutaneous tumor model in vivo. J. Drug Target. 13(6), 337-343 (2005). (Pubitemid 41683987)
    • (2005) Journal of Drug Targeting , vol.13 , Issue.6 , pp. 337-343
    • Gupta, B.1    Levchenko, T.S.2    Mongayt, D.A.3    Torchilin, V.P.4
  • 109
    • 7444236397 scopus 로고    scopus 로고
    • Tumor-targeted liposomes: Doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody
    • DOI 10.1016/j.jconrel.2004.08.007, PII S0168365904003797
    • Lukyanov AN, Elbayoumi TA, Chakilam AR, Torchilin VP: Tumor-targeted liposomes: doxorubicin-loaded long-circulating liposomes modified with anti-cancer antibody. J. Control. Release 100(1), 135-144 (2004). (Pubitemid 39445991)
    • (2004) Journal of Controlled Release , vol.100 , Issue.1 , pp. 135-144
    • Lukyanov, A.N.1    Elbayoumi, T.A.2    Chakilam, A.R.3    Torchilin, V.P.4
  • 110
    • 28044454060 scopus 로고    scopus 로고
    • A single monoclonal antinuclear autoantibody with nucleosome-restricted specificity inhibits growth of diverse human tumors in nude mice
    • Chakilam AR, Pabba S, Mongayt D, Iakoubov LZ, Torchilin VP. A single monoclonal antinuclear autoantibody with nucleosome-restricted specificity inhibits growth of diverse human tumors in nude mice. Cancer Ther. 2, 353-364 (2004).
    • (2004) Cancer Ther. , vol.2 , pp. 353-364
    • Chakilam, A.R.1    Pabba, S.2    Mongayt, D.3    Iakoubov, L.Z.4    Torchilin, V.P.5
  • 111
    • 33749255196 scopus 로고    scopus 로고
    • Enhanced accumulation of long-circulating liposomes modified with the nucleosome-specific monoclonal antibody 2C5 in various tumours in mice: Gamma-imaging studies
    • DOI 10.1007/s00259-006-0139-x
    • Elbayoumi TA, Torchilin VP. Enhanced accumulation of long-circulating liposomes modified with the nucleosome-specific monoclonal antibody 2C5 in various tumours in mice: g-imaging studies. Eur. J. Nucl. Med. Mol. Imaging 33(10), 1196-1205 (2006). (Pubitemid 44484476)
    • (2006) European Journal of Nuclear Medicine and Molecular Imaging , vol.33 , Issue.10 , pp. 1196-1205
    • Elbayoumi, T.A.1    Torchilin, V.P.2
  • 112
    • 0037115543 scopus 로고    scopus 로고
    • Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs
    • Sapra P, Allen TM. Internalizing antibodies are necessary for improved therapeutic efficacy of antibody-targeted liposomal drugs. Cancer Res. 62(24), 7190-7194 (2002). (Pubitemid 36025236)
    • (2002) Cancer Research , vol.62 , Issue.24 , pp. 7190-7194
    • Sapra, P.1    Allenz, T.M.2
  • 113
    • 25444471028 scopus 로고    scopus 로고
    • Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved antitumor efficacy: In vitro and in vivo
    • DOI 10.1002/jps.20397
    • Xiong XB, Huang Y, Lu WL et al. Intracellular delivery of doxorubicin with RGD-modified sterically stabilized liposomes for an improved anti-tumor efficacy: in vitro and in vivo. J. Pharm. Sci. 94(8), 1782-1793 (2005). (Pubitemid 41360872)
    • (2005) Journal of Pharmaceutical Sciences , vol.94 , Issue.8 , pp. 1782-1793
    • Xiong, X.-B.1    Huang, Y.2    Lu, W.-L.3    Zhang, X.4    Zhang, H.5    Nagai, T.6    Zhang, Q.7
  • 114
    • 21244494846 scopus 로고    scopus 로고
    • Enhanced intracellular uptake of sterically stabilized liposomal doxorubicin in Vitro resulting in improved antitumor activity in Vivo
    • DOI 10.1007/s11095-005-4588-x
    • Xiong XB, Huang Y, Lu WL, Zhang H, Zhang X, Zhang Q. Enhanced intracellular uptake of sterically stabilized liposomal doxorubicin in vitro resulting in improved antitumor activity in vivo. Pharm. Res. 22(6), 933-939 (2005). (Pubitemid 40898103)
    • (2005) Pharmaceutical Research , vol.22 , Issue.6 , pp. 933-939
    • Xiong, X.-B.1    Huang, Y.2    Lu, W.-L.3    Zhang, H.4    Zhang, X.5    Zhang, Q.6
  • 115
    • 0001636498 scopus 로고
    • Liposomes and hyperthermia in mice: Increased tumor uptake and therapeutic efficacy of doxorubicin in sterically stabilized liposomes
    • Huang SK, Stauffer PR, Hong K et al. Liposomes and hyperthermia in mice: increased tumor uptake and therapeutic efficacy of doxorubicin in sterically stabilized liposomes. Cancer Res. 54(8), 2186-2191 (1994). (Pubitemid 24138693)
    • (1994) Cancer Research , vol.54 , Issue.8 , pp. 2186-2191
    • Huang, S.K.1    Stauffer, P.R.2    Hong, K.3    Guo, J.W.H.4    Phillips, T.L.5    Huang, A.6    Papahadjopoulos, D.7
  • 117
    • 34948876843 scopus 로고    scopus 로고
    • Enhanced cytotoxicity of monoclonal anticancer antibody 2C5-modified doxorubicin-loaded PEGylated liposomes against various tumor cell lines
    • DOI 10.1016/j.ejps.2007.05.113, PII S0928098707002552
    • Elbayoumi TA, Torchilin VP. Enhanced cytotoxicity of monoclonal anticancer antibody 2C5-modified doxorubicin-loaded pegylated liposomes against various tumor cell lines. Eur. J. Pharm. Sci. 32(3), 159-168 (2007). (Pubitemid 47532709)
    • (2007) European Journal of Pharmaceutical Sciences , vol.32 , Issue.3 , pp. 159-168
    • Elbayoumi, T.A.1    Torchilin, V.P.2
  • 118
    • 62649125368 scopus 로고    scopus 로고
    • Tumor-specific antinucleosome antibody improves therapeutic efficacy of doxorubicin-loaded long-circulating liposomes against primary and metastatic tumor in mice
    • Elbayoumi TA, Torchilin VP. Tumor-specific antinucleosome antibody improves therapeutic efficacy of doxorubicin-loaded long-circulating liposomes against primary and metastatic tumor in mice. Mol. Pharm. 6(1), 246-254 (2009).
    • (2009) Mol. Pharm. , vol.6 , Issue.1 , pp. 246-254
    • Elbayoumi, T.A.1    Torchilin, V.P.2
  • 119
    • 63549094211 scopus 로고    scopus 로고
    • Tumor-targeted nanomedicines: Enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody
    • ElBayoumi TA, Torchilin VP. Tumor-targeted nanomedicines: enhanced antitumor efficacy in vivo of doxorubicin-loaded, long-circulating liposomes modified with cancer-specific monoclonal antibody. Clin. Cancer Res. 15(6), 1973-1980 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , Issue.6 , pp. 1973-1980
    • Elbayoumi, T.A.1    Torchilin, V.P.2
  • 120
    • 0002685062 scopus 로고
    • Chabner BA, Collings JM (Eds). Lippincott, Williams & Wilkins Philadelphia, PA, USA
    • Chabner BA. Cancer Chemotherapy: Principles and Practice. Chabner BA, Collings JM (Eds). Lippincott, Williams & Wilkins Philadelphia, PA, USA (1990).
    • (1990) Cancer Chemotherapy: Principles and Practice
    • Chabner, B.A.1
  • 121
    • 0025111760 scopus 로고
    • Relationships in the structure-tissue distribution of basic drugs in the rabbit
    • DOI 10.1023/A:1015803202857
    • Yokogawa K, Nakashima E, Ishizaki J, Maeda H, Nagano T, Ichimura F. Relationships in the structure-tissue distribution of basic drugs in the rabbit. Pharm. Res. 7(7), 691-696 (1990). (Pubitemid 20278364)
    • (1990) Pharmaceutical Research , vol.7 , Issue.7 , pp. 691-696
    • Yokogawa, K.1    Nakashima, E.2    Ishizaki, J.3    Maeda, H.4    Nagano, T.5    Ichimura, F.6
  • 122
    • 0028175796 scopus 로고
    • Lipophilic b-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins
    • Hageluken A, Grunbaum L, Nurnberg B, Harhammer R, Schunack W, Seifert R. Lipophilic b-adrenoceptor antagonists and local anesthetics are effective direct activators of G-proteins. Biochem. Pharmacol. 47(10), 1789-1795 (1994).
    • (1994) Biochem. Pharmacol. , vol.47 , Issue.10 , pp. 1789-1795
    • Hageluken, A.1    Grunbaum, L.2    Nurnberg, B.3    Harhammer, R.4    Schunack, W.5    Seifert, R.6
  • 124
    • 33845388144 scopus 로고    scopus 로고
    • Micellar nanocarriers: Pharmaceutical perspectives
    • DOI 10.1007/s11095-006-9132-0
    • Torchilin VP. Micellar nanocarriers: pharmaceutical perspectives. Pharm. Res. 24(1), 1-16 (2007). (Pubitemid 44902565)
    • (2007) Pharmaceutical Research , vol.24 , Issue.1 , pp. 1-16
    • Torchilin, V.P.1
  • 126
    • 0344061534 scopus 로고    scopus 로고
    • Solubility and stability of tetrazepam in mixed micelles
    • DOI 10.1016/S0928-0987(98)00006-2, PII S0928098798000062
    • Hammad MA, Muller BW. Solubility and stability of tetrazepam in mixed micelles. Eur. J. Pharm. Sci. 7(1), 49-55 (1998). (Pubitemid 29056226)
    • (1998) European Journal of Pharmaceutical Sciences , vol.7 , Issue.1 , pp. 49-55
    • Hammad, M.A.1    Muller, B.W.2
  • 128
    • 0029360317 scopus 로고
    • Liposome circulation time and tumor targeting: Implications for cancer chemotherapy
    • Gabizon AA. Liposome circulation time and tumor targeting: implications for cancer chemotherapy. Adv. Drug Deliv. Rev. 16, 285-294 (1995).
    • (1995) Adv. Drug Deliv. Rev. , vol.16 , pp. 285-294
    • Gabizon, A.A.1
  • 129
    • 0028304405 scopus 로고
    • Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft
    • Yuan F, Leunig M, Huang SK, Berk DA, Papahadjopoulos D, Jain RK. Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft. Cancer Res. 54(13), 3352-3356 (1994). (Pubitemid 24225946)
    • (1994) Cancer Research , vol.54 , Issue.13 , pp. 3352-3356
    • Yuan, F.1    Leunig, M.2    Huang, S.K.3    Berk, D.A.4    Papahadjopoulos, D.5    Jain, R.K.6
  • 130
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • DOI 10.1016/S0168-3659(99)00248-5, PII S0168365999002485
    • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. J. Control. Release 65(1-2), 271-284 (2000). (Pubitemid 30122932)
    • (2000) Journal of Controlled Release , vol.65 , Issue.1-2 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 131
    • 0035816204 scopus 로고    scopus 로고
    • Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
    • DOI 10.1016/S0168-3659(01)00309-1, PII S0168365901003091
    • Maeda H, Sawa T, Konno T. Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J. Control. Release 74(1-3), 47-61 (2001). (Pubitemid 32727608)
    • (2001) Journal of Controlled Release , vol.74 , Issue.1-3 , pp. 47-61
    • Maeda, H.1    Sawa, T.2    Konno, T.3
  • 132
    • 0032778659 scopus 로고    scopus 로고
    • Polymeric micelles - A new generation of colloidal drug carriers
    • DOI 10.1016/S0939-6411(99)00039-9, PII S0939641199000399
    • Jones M, Leroux J. Polymeric micelles - a new generation of colloidal drug carriers. Eur. J. Pharm. Biopharm. 48(2), 101-111 (1999). (Pubitemid 29401986)
    • (1999) European Journal of Pharmaceutics and Biopharmaceutics , vol.48 , Issue.2 , pp. 101-111
    • Jones, M.-C.1    Leroux, J.-C.2
  • 133
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • DOI 10.1016/S0168-3659(01)00299-1, PII S0168365901002991
    • Torchilin VP. Structure and design of polymeric surfactant-based drug delivery systems. J. Control. Release 73(2-3), 137-172 (2001). (Pubitemid 32544594)
    • (2001) Journal of Controlled Release , vol.73 , Issue.2-3 , pp. 137-172
    • Torchilin, V.P.1
  • 134
    • 0023280158 scopus 로고
    • Fate and behavior of liposomes in vivo: A review of controlling factors
    • Senior JH. Fate and behavior of liposomes in vivo: a review of controlling factors. Crit. Rev. Ther. Drug Carrier Syst. 3(2), 123-193 (1987). (Pubitemid 17219201)
    • (1987) Critical Reviews in Therapeutic Drug Carrier Systems , vol.3 , Issue.2 , pp. 123-193
    • Senior, J.H.1
  • 135
    • 0029360322 scopus 로고
    • Which polymers can make nanoparticulate drug carriers long-circulating?
    • Torchilin VP, Trubetskoy VS. Which polymers can make nanoparticulate drug carriers long-circulating? Adv. Drug Deliv. Rev. 16(2), 141-155 (1995).
    • (1995) Adv. Drug Deliv. Rev. , vol.16 , Issue.2 , pp. 141-155
    • Torchilin, V.P.1    Trubetskoy, V.S.2
  • 136
    • 0029360480 scopus 로고
    • Use of polyoxyethylene-lipid conjugates as long-circulating carriers for delivery of therapeutic and diagnostic agents
    • Trubetskoy VS, Torchilin VP. Use of polyoxyethylene-lipid conjugates as long-circulating carriers for delivery of therapeutic and diagnostic agents. Adv. Drug Deliv. Rev. 16, 311-320 (1995).
    • (1995) Adv. Drug Deliv. Rev. , vol.16 , pp. 311-320
    • Trubetskoy, V.S.1    Torchilin, V.P.2
  • 139
    • 0038268753 scopus 로고    scopus 로고
    • PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing
    • DOI 10.1080/1061186031000138623
    • Gao Z, Lukyanov AN, Chakilam AR, Torchilin VP. PEG-PE/phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing. J. Drug Target. 11(2), 87-92 (2003). (Pubitemid 36869181)
    • (2003) Journal of Drug Targeting , vol.11 , Issue.2 , pp. 87-92
    • Gao, Z.1    Lukyanov, A.N.2    Chakilam, A.R.3    Torchilin, V.P.4
  • 140
    • 50149092136 scopus 로고    scopus 로고
    • Mixed PEG-PE/vitamin e tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: Improved drug solubilization and enhanced in vitro cytotoxicity
    • Sawant RR, Sawant RM, Torchilin VP. Mixed PEG-PE/vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: improved drug solubilization and enhanced in vitro cytotoxicity. Eur. J. Pharm. Biopharm. 70(1), 51-57 (2008).
    • (2008) Eur. J. Pharm. Biopharm. , vol.70 , Issue.1 , pp. 51-57
    • Sawant, R.R.1    Sawant, R.M.2    Torchilin, V.P.3
  • 141
    • 70349566804 scopus 로고    scopus 로고
    • In vitro cytotoxicity of novel pro-apoptotic agent DM-PIT-1 in PEG-PE-based micelles alone and in combination with trail
    • Skidan I, Miao B, Thekkedath RV, Dholakia P, Degterev A, Torchilin V. In vitro cytotoxicity of novel pro-apoptotic agent DM-PIT-1 in PEG-PE-based micelles alone and in combination with trail. Drug Deliv. 16(1), 45-51 (2009).
    • (2009) Drug Deliv. , vol.16 , Issue.1 , pp. 45-51
    • Skidan, I.1    Miao, B.2    Thekkedath, R.V.3    Dholakia, P.4    Degterev, A.5    Torchilin, V.6
  • 142
    • 33644818008 scopus 로고    scopus 로고
    • Solubilization of poorly soluble PDT agent, meso-tetraphenylporphin, in plain or immunotargeted PEG-PE micelles results in dramatically improved cancer cell killing in vitro
    • DOI 10.1016/j.ejpb.2005.09.010, PII S0939641105002596
    • Roby A, Erdogan S, Torchilin VP. Solubilization of poorly soluble PDT agent, meso-tetraphenylporphin, in plain or immunotargeted PEG-PE micelles results in dramatically improved cancer cell killing in vitro. Eur. J. Pharm. Biopharm. 62(3), 235-240 (2006). (Pubitemid 43356570)
    • (2006) European Journal of Pharmaceutics and Biopharmaceutics , vol.62 , Issue.3 , pp. 235-240
    • Roby, A.1    Erdogan, S.2    Torchilin, V.P.3
  • 143
    • 42449109937 scopus 로고    scopus 로고
    • Enhanced in vivo anti-tumor efficacy of poorly soluble PDT agent, meso-tetraphenylporphine, in PEG-PE-based tumor-targeted immunomicelles
    • Roby A, Erdogan S, Torchilin VP. Enhanced in vivo anti-tumor efficacy of poorly soluble PDT agent, meso-tetraphenylporphine, in PEG-PE-based tumor-targeted immunomicelles. Cancer Biol. Ther. 6(7), (2007).
    • (2007) Cancer Biol. Ther. , vol.6 , pp. 7
    • Roby, A.1    Erdogan, S.2    Torchilin, V.P.3
  • 144
    • 47649099709 scopus 로고    scopus 로고
    • Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20-tetraphenylporphin-loaded PEG-PE micelles
    • DOI 10.1080/10611860802102175, PII 794751680
    • Skidan I, Dholakia P, Torchilin V. Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20-tetraphenylporphin-loaded PEG-PE micelles. J. Drug Target. 16(6), 486-493 (2008). (Pubitemid 352015817)
    • (2008) Journal of Drug Targeting , vol.16 , Issue.6 , pp. 486-493
    • Skidan, I.1    Dholakia, P.2    Torchilin, V.P.3
  • 145
    • 42949172881 scopus 로고    scopus 로고
    • Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery
    • DOI 10.2217/17435889.3.2.247
    • Ljubimova JY, Fujita M, Ljubimov AV, Torchilin VP, Black KL, Holler E. Poly(malic acid) nanoconjugates containing various antibodies and oligonucleotides for multitargeting drug delivery. Nanomedicine 3(2), 247-265 (2008). (Pubitemid 351611858)
    • (2008) Nanomedicine , vol.3 , Issue.2 , pp. 247-265
    • Ljubimova, J.Y.1    Fujita, M.2    Ljubimov, A.V.3    Torchilin, V.P.4    Black, K.L.5    Holler, E.6
  • 146
    • 70349734672 scopus 로고    scopus 로고
    • Nanosized cancer cell-targeted polymeric immunomicelles loaded with supermagnetic iron oxide nanoparticles
    • Sawant RM, Sawant RR, Gultepe E et al. Nanosized cancer cell-targeted polymeric immunomicelles loaded with supermagnetic iron oxide nanoparticles. J. Nanopart. Res. 11(7), 1777-1785 (2009).
    • (2009) J. Nanopart. Res. , vol.11 , Issue.7 , pp. 1777-1785
    • Sawant, R.M.1    Sawant, R.R.2    Gultepe, E.3
  • 147
    • 33750404842 scopus 로고    scopus 로고
    • 111In-labeled polychelating-polymer-containing immunoliposomes
    • DOI 10.1021/mp060055t
    • Erdogan S, Roby A, Torchilin VP. Enhanced tumor visualization by g-scintigraphy with 111In-labeled polychelating-polymer-containing immunoliposomes. Mol. Pharm. 3(5), 525-530 (2006). (Pubitemid 44639129)
    • (2006) Molecular Pharmaceutics , vol.3 , Issue.5 , pp. 525-530
    • Erdogan, S.1    Roby, A.2    Torchilin, V.P.3
  • 148
    • 33645371777 scopus 로고    scopus 로고
    • Gadolinium-loaded polychelating polymer-containing cancer cell-specific immunoliposomes
    • Erdogan S, Roby A, Sawant R, Hurley J, Torchilin VP. Gadolinium-loaded polychelating polymer-containing cancer cell-specific immunoliposomes. J. Liposome Res. 16(1), 45-55 (2006).
    • (2006) J. Liposome Res. , vol.16 , Issue.1 , pp. 45-55
    • Erdogan, S.1    Roby, A.2    Sawant, R.3    Hurley, J.4    Torchilin, V.P.5
  • 149
    • 40449112920 scopus 로고    scopus 로고
    • Enhanced tumor MR imaging with gadolinium-loaded polychelating polymer-containing tumor-targeted liposomes
    • DOI 10.1002/jmri.21202
    • Erdogan S, Medarova ZO, Roby A, Moore A, Torchilin VP. Enhanced tumor MR imaging with gadolinium-loaded polychelating polymer-containing tumor-targeted liposomes. J. Magn. Reson. Imaging 27(3), 574-580 (2008). (Pubitemid 351354743)
    • (2008) Journal of Magnetic Resonance Imaging , vol.27 , Issue.3 , pp. 574-580
    • Erdogan, S.1    Medarova, Z.O.2    Roby, A.3    Moore, A.4    Torchilin, V.P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.