Co-delivery of chemotherapeutic drugs with vitamin E TPGS by porous PLGA nanoparticles for enhanced chemotherapy against multi-drug resistance

Biomaterials

Volumn 35, Issue 7, 2014, Pages 2391-2400

  Zhu, Huijun ^a   Chen, Hongbo ^a   Zeng, Xiaowei ^a   Wang, Zhongyuan ^a   Zhang, Xudong ^a   Wu, Yanping ^a   Gao, Yongfeng ^a   Zhang, Jinxie ^a   Liu, Kewei ^a   Liu, Ranyi ^b   Cai, Lintao ^c   Mei, Lin ^a   Feng, Si Shen ^a,d  

^a TSINGHUA UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^c SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Biodegradable polymers; Cancer nanotechnology; Controlled release; Molecular biomaterial; Nanomedicine; Pharmaceutical nanotechnology

Indexed keywords

CANCER NANOTECHNOLOGY; CONTROLLED RELEASE; DRUG ENCAPSULATION EFFICIENCY; ENCAPSULATION EFFICIENCY; IMMUNO-HISTOLOGICAL STAINING; NANOPRECIPITATION METHOD; POLY LACTIC-CO-GLYCOLIC ACID; SIZE AND SIZE DISTRIBUTIONS;

BIODEGRADABLE POLYMERS; BIOLOGICAL MATERIALS; CHEMOTHERAPY; DRUG PRODUCTS; ENCAPSULATION; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; NANOTECHNOLOGY;

COPOLYMERS;

DOCETAXEL; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; NANOPARTICLE; POLYGLACTIN; TOCOFERSOLAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG POTENTIATION; DRUG RELEASE; FEMALE; HUMAN; HUMAN CELL; IC 50; IMMUNOHISTOLOGY; IN VITRO STUDY; MICROTUBULE ASSEMBLY; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR GROWTH; ZETA POTENTIAL;

BIODEGRADABLE POLYMERS; CANCER NANOTECHNOLOGY; CONTROLLED RELEASE; MOLECULAR BIOMATERIAL; NANOMEDICINE; PHARMACEUTICAL NANOTECHNOLOGY;

ANTINEOPLASTIC AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; DRUG CARRIERS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HELA CELLS; HUMANS; LACTIC ACID; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; P-GLYCOPROTEIN; PARTICLE SIZE; POLYGLYCOLIC ACID; THERMOGRAVIMETRY; VITAMIN E;

EID: 84891373113     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.11.086     Document Type: Article

References (39)

1. Gottesman M.M., Fojo T., Bates S.E. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002, 2:48-58.
2. Wang J., Sun J., Chen Q., Gao Y., Li L., Li H., et al. Star-shape copolymer of lysine-linked di-tocopherol polyethylene glycol 2000 succinate for doxorubicin delivery with reversal of multidrug resistance. Biomaterials 2012, 33(28):6877-6888.
3. Lake D.E., Hudis C.A. High-dose chemotherapy in breast cancer. Drugs 2004, 64:1851-1860.
4. Kumbar S.G., Nair L.S., Bhattacharyya S., Laurencin C.T. Polymeric nanofibers as novel carriers for the delivery of therapeutic molecules. JNanosci Nanotechnol 2006, 6:2591-2607.
5. Reddy L.H., Dubernet C., Mouelhi S.L., Marque P.E., Desmaele D., Couvreur P. Anew nanomedicine of gemcitabine displays enhanced anticancer activity in sensitive and resistant leukemia types. JControl Release 2007, 124(1-2):20-27.
6. Dorai T., Aggarwal B.B. Role of chemopreventive agents in cancer therapy. Cancer Lett 2004, 215:129-140.
7. Gao Y., Chen Y., Ji X., He X., Yin Q., Zhang Z., et al. Controlled intracellular release of doxorubicin in multidrug-resistant cancer cells by tuning the shell-pore sizes of mesoporous silica nanoparticles. ACS Nano 2011, 5(12):9788-9798.
8. Zhang Y., Tang L., Sun L., Bao J., Song C., Huang L., et al. Anovel paclitaxel-loaded poly(epsilon-caprolactone)/poloxamer 188 blend nanoparticle overcoming multidrug resistance for cancer treatment. Acta Biomater 2010, 6(6):2045-2052.
9. Yan F., Zhang C., Zheng Y., Mei L., Tang L., Song C., et al. The effect of poloxamer 188 on nanoparticle morphology, size, cancer cell uptake, and cytotoxicity. Nanomedicine:NBM 2010, 6(1):170-178.
10. Gelperina S., Kisich K., Iseman M.D., Heifets L. The potential advantages of nanoparticle drug delivery systems in chemotherapy of tuberculosis. Am J Respir Crit Care Med 2005, 172:1487-1490.
11. Hu C.M., Zhang L. Therapeutic nanoparticles to combat cancer drug resistance. Curr Drug Metab 2009, 10(8):836-841.
12. Brigger I., Dubernet C., Couvreur P. Nanoparticles in cancer therapy and diagnosis. Adv Drug Deliv Rev 2002, 54:631-651.
13. Park W., Kim D., Kang H.C., Bae Y.H., Na K. Multi-arm histidine copolymer for controlled release of insulin from poly(lactide-co-glycolide) microsphere. Biomaterials 2012, 33:8848-8857.
14. Viswanathan N.B., Patil S.S., Pandit J.K., Lele A.K., Kulkarni M.G., Mashelkar R.A. Morphological changes in degrading PLGA and P(DL)LA microspheres: implications for the design of controlled release systems. JMicroencapsul 2001, 18:783-800.
15. Kang J., Schwendeman S.P. Pore closing and opening in biodegradable polymers and their effect on the controlled release of proteins. Mol Pharmacol 2007, 4(1):104-118.
16. Ke C.J., Lin Y.J., Hu Y.C., Chiang W.L., Chen K.J., Yang W.C., et al. Multidrug release based on microneedle arrays filled with pH-responsive PLGA hollow microspheres. Biomaterials 2012, 33:5156-5165.
17. Yang Y., Bajaj N., Xu P., Ohn K., Tsifansky M.D., Yeo Y. Development of highly porous large PLGA microparticles for pulmonary drug delivery. Biomaterials 2009, 30:1947-1953.
18. Bae S.E., Son J.S., Park K., Han D.K. Fabrication of covered porous PLGA microspheres using hydrogen peroxide for controlled drug delivery and regenerative medicine. JControl Release 2009, 133(1):37-43.
19. Buske J., Konig C., Bassarab S., Lamprecht A., Muhlau S., Wagner K.G. Influence of PEG in PEG-PLGA microspheres on particle properties and protein release. Eur J Pharm Biopharm 2012, 81(1):57-63.
20. Mitra S., Gaur U., Ghosh P.C., Maitra A.N. Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier. JControl Release 2001, 74(1-3):317-323.
21. Win K.Y., Feng S.S. Effects of particle size and surface coating on cellular uptake of polymeric nanoparticles for oral delivery of anticancer drugs. Biomaterials 2005, 26:2713-2722.
22. Zhang Z., Tan S., Feng S.S. Vitamin E TPGS as a molecular biomaterial for drug delivery. Biomaterials 2012, 33:4889-4906.
23. Zhang Z., Mei L., Feng S.S. Vitamin E D-α-tocopheryl polyethylene glycol 1000 succinate-based nanomedicine. Nanomedicine 2012, 7(11):1645-1647.
24. Dintaman J.M., Silverman J.A. Inhibition of P-glycoprotein by D-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS). Pharm Res 1999, 16(10):1550-1556.
25. Youk H.J., Lee E., Choi M.K., Lee Y.J., Chung J.H., Kim S.H., et al. Enhanced anticancer efficacy of alpha-tocopheryl succinate by conjugation with polyethylene glycol. JControl Release 2005, 107:43-52.
26. Constantinou C., Papas A., Constantinou A.I. Vitamin E and cancer: an insight into the anticancer activities of vitamin E isomers and analogs. Int J Cancer 2008, 123(4):739-752.
27. Neuzil J., Tomasetti M., Zhao Y., Dong L.F., Birringer M., Wang X.F., et al. Vitamin E analogs, a novel group of "mitocans," as anticancer agents: the importance of being redox-silent. Mol Pharmacol 2007, 71(5):1185-1199.
28. Cheng J., Teply B.A., Sherifi I., Sung J., Luther G., Gu F.X., et al. Formulation of functionalized PLGA-PEG nanoparticles for invivo targeted drug delivery. Biomaterials 2007, 28(5):869-876.
29. Zeng X., Tao W., Mei L., Huang L., Tan C., Feng S.S. Cholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer. Biomaterials 2013, 34(25):6058-6067.
30. Tao W., Zeng X., Liu T., Wang Z., Xiong Q., Ouyang C., et al. Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy. Acta Biomater 2013, 9(11):8910-8920.
31. Dai X., Yue Z., Eccleston M.E., Swartling J., Slater N.K., Kaminski C.F. Fluorescence intensity and lifetime imaging of free and micellar-encapsulated doxorubicin in living cells. Nanomedicine:NBM 2008, 4(1):49-56.
32. Ke C.J., Su T.Y., Chen H.L., Liu H.L., Chiang W.L., Chu P.C., et al. Smart multifunctional hollow microspheres for the quick release of drugs in intracellular lysosomal compartments. Angewandte Chemie 2011, 50:8086-8089.
33. Perrault S.D., Walkey C., Jennings T., Fischer H.C., Chan W.C. Mediating tumor targeting efficiency of nanoparticles through design. Nano Lett 2009, 9:1909-1915.
34. Schubert M.A., Müller-Goymann C.C. Characterisation of surface-modified solid lipid nanoparticles (SLN): influence of lecithin and nonionic emulsifier. Eur J Pharm Biopharm 2005 Sep, 61(1-2):77-86.
35. Verma A., Stellacci F. Effect of surface properties on nanoparticle-cell interactions. Small 2010, 6:12-21.
36. He C., Hu Y., Yin L., Tang C., Yin C. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 2010, 31(13):3657-3666.
37. Mu L., Feng S.S. Vitamin E TPGS used as emulsifier in the solvent evaporation/extraction technique for fabrication of polymeric nanospheres for controlled release of paclitaxel (Taxol). JControl Release 2002, 80:129-144.
38. Ma Y., Zheng Y., Liu K., Tian G., Tian Y., Xu L., et al. Nanoparticles of poly(Lactide-Co-Glycolide)-d-a-Tocopheryl polyethylene glycol 1000 succinate random copolymer for cancer treatment. Nanoscale Res Lett 2010, 5(7):1161-1169.
39. Sant S., Nadeau V., Hildgen P. Effect of porosity on the release kinetics of propafenone-loaded PEG-g-PLA nanoparticles. JControl Release 2005, 107(2):203-214.