Formononetin potentiates epirubicin-induced apoptosis via ROS production in HeLa cells in vitro

Chemico-Biological Interactions

Volumn 205, Issue 3, 2013, Pages 188-197

  Lo, Yu Li ^a   Wang, Wanjen ^a  

^a NATIONAL UNIVERSITY OF TAINAN   (Taiwan)

Author keywords

Apoptosis; Epirubicin; Formononetin; Isoflavone; Multidrug resistance; Reactive oxygen species

Indexed keywords

ACETYLCYSTEINE; CASPASE 3; CASPASE 8; CASPASE 9; EPIRUBICIN; FORMONONETIN; FREE RADICAL; HYDROGEN PEROXIDE; ISOFLAVONE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE;

APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CHEMOSENSITIVITY; CHROMATIN CONDENSATION; CORRELATION ANALYSIS; DNA FRAGMENTATION; DRUG DETERMINATION; DRUG EFFICACY; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME SYNTHESIS; G2 PHASE CELL CYCLE CHECKPOINT; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MULTIDRUG RESISTANCE; PROTEIN EXPRESSION; UTERINE CERVIX CANCER;

ΔΨ(M); 3,3′-DIHEXYLOXACARBOCYANINE IODIDE; 3-(4,5-DIMETHYLTHIAZOL-2-YL)-2,5-DIPHENYL TETRAZOLIUM BROMIDE; APOPTOSIS; DCF; DICHLOROFLUORESCEIN; DIOC(6); EPIRUBICIN; ETBR; ETHIDIUM BROMIDE; FORMONONETIN; HELA; HUMAN CERVICAL CANCER CELLS; ISOFLAVONE; MDR; MDR-ASSOCIATED PROTEINS; MITOCHONDRIAL TRANSMEMBRANE POTENTIAL; MRPS; MTT; MULTIDRUG RESISTANCE; P-GLYCOPROTEIN; P-GP; REACTIVE OXYGEN SPECIES; ROS; TNF-ALPHA; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRAIL; TUMOR NECROSIS FACTOR-ALPHA;

ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL SURVIVAL; DRUG SYNERGISM; EPIRUBICIN; FEMALE; FLOW CYTOMETRY; HELA CELLS; HUMANS; ISOFLAVONES; MEMBRANE POTENTIAL, MITOCHONDRIAL; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; P-GLYCOPROTEIN; PHYTOESTROGENS; PROTO-ONCOGENE PROTEINS C-BCL-2; REAL-TIME POLYMERASE CHAIN REACTION; RNA, NEOPLASM; UTERINE CERVICAL NEOPLASMS;

EID: 84881189488     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2013.07.003     Document Type: Article

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