-
1
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
Ambudkar S.V., Dey S., Hrycyna C.A., Ramachandra M., Pastan I., and Gottesman M.M. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu. Rev. Pharmacol. Toxicol. 39 (1999) 361-398
-
(1999)
Annu. Rev. Pharmacol. Toxicol.
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
2
-
-
33644775686
-
Targeting multidrug resistance in cancer
-
Szakács G., Paterson J.K., Ludwig J.A., Booth-Genthe C., and Gottesman M.M. Targeting multidrug resistance in cancer. Nat. Rev. Drug Discov. 5 (2006) 219-234
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 219-234
-
-
Szakács, G.1
Paterson, J.K.2
Ludwig, J.A.3
Booth-Genthe, C.4
Gottesman, M.M.5
-
3
-
-
33749488939
-
Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system
-
Sarkadi B., Homolya L., Szakács G., and Valádi A. Human multidrug resistance ABCB and ABCG transporters: participation in a chemoimmunity defense system. Physiol. Rev. 86 (2006) 1179-1236
-
(2006)
Physiol. Rev.
, vol.86
, pp. 1179-1236
-
-
Sarkadi, B.1
Homolya, L.2
Szakács, G.3
Valádi, A.4
-
4
-
-
0000598335
-
Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells
-
Roninson I.B., Chin J.E., Choi K.G., Gros P., Housman D.E., Fojo A., Shen D.W., Gottesman M.M., and Pastan I. Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. Proc. Natl. Acad. Sci. USA 83 (1986) 4538-4542
-
(1986)
Proc. Natl. Acad. Sci. USA
, vol.83
, pp. 4538-4542
-
-
Roninson, I.B.1
Chin, J.E.2
Choi, K.G.3
Gros, P.4
Housman, D.E.5
Fojo, A.6
Shen, D.W.7
Gottesman, M.M.8
Pastan, I.9
-
5
-
-
0035957037
-
Stanol/sterol ester-containing foods and blood cholesterol levels. A statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association
-
Lichtenstein A.H., and Deckelbaum R.J. Stanol/sterol ester-containing foods and blood cholesterol levels. A statement for healthcare professionals from the Nutrition Committee of the Council on Nutrition, Physical Activity, and Metabolism of the American Heart Association. Circulation 103 (2001) 1177-1179
-
(2001)
Circulation
, vol.103
, pp. 1177-1179
-
-
Lichtenstein, A.H.1
Deckelbaum, R.J.2
-
6
-
-
0042206849
-
Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels
-
Katan M.B., Grundy S.M., Jones P., Law M., Miettinen T., and Paoletti R. Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin. Proc. 78 (2003) 965-978
-
(2003)
Mayo Clin. Proc.
, vol.78
, pp. 965-978
-
-
Katan, M.B.1
Grundy, S.M.2
Jones, P.3
Law, M.4
Miettinen, T.5
Paoletti, R.6
-
7
-
-
0033851608
-
Phytosterols as anticancer dietary components: evidence and mechanism of action
-
Awad A.B., and Fink C.S. Phytosterols as anticancer dietary components: evidence and mechanism of action. J. Nutr. 130 (2000) 2127-2130
-
(2000)
J. Nutr.
, vol.130
, pp. 2127-2130
-
-
Awad, A.B.1
Fink, C.S.2
-
8
-
-
33750927892
-
ATP-binding cassette cholesterol transporters and cardiovascular disease
-
Oran J.F., and Vaughan A.M. ATP-binding cassette cholesterol transporters and cardiovascular disease. Circ. Res. 99 (2006) 1031-1043
-
(2006)
Circ. Res.
, vol.99
, pp. 1031-1043
-
-
Oran, J.F.1
Vaughan, A.M.2
-
9
-
-
0021905666
-
Isolation and genetic characterization of human KB cell lines resistant to multiple drugs
-
Akiyama S., Fojo A., Hanover J.A., Pastan I., and Gottesman M.M. Isolation and genetic characterization of human KB cell lines resistant to multiple drugs. Som. Cell Mol. Genet. 11 (1985) 117-126
-
(1985)
Som. Cell Mol. Genet.
, vol.11
, pp. 117-126
-
-
Akiyama, S.1
Fojo, A.2
Hanover, J.A.3
Pastan, I.4
Gottesman, M.M.5
-
10
-
-
0031032495
-
Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP)
-
Taguchi Y., Yoshida A., Takada Y., Komano T., and Ueda K. Anti-cancer drugs and glutathione stimulate vanadate-induced trapping of nucleotide in multidrug resistance-associated protein (MRP). FEBS Lett. 401 (1997) 11-14
-
(1997)
FEBS Lett.
, vol.401
, pp. 11-14
-
-
Taguchi, Y.1
Yoshida, A.2
Takada, Y.3
Komano, T.4
Ueda, K.5
-
11
-
-
11844301652
-
Effects of dietary chemopreventive phytochemicals on P-glycoprotein function
-
Nabekura T., Kamiyama S., and Kitagawa S. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function. Biochem. Biophys. Res. Commun. 327 (2005) 866-870
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.327
, pp. 866-870
-
-
Nabekura, T.1
Kamiyama, S.2
Kitagawa, S.3
-
12
-
-
20344395587
-
Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds
-
Wortelboer H.M., Usta M., van Zanden J.J., van Bladeren P.J., Rietjens I.M.C.M., and Cnubben N.H.P. Inhibition of multidrug resistance proteins MRP1 and MRP2 by a series of α,β-unsaturated carbonyl compounds. Biochem. Pharmacol. 69 (2005) 1879-1890
-
(2005)
Biochem. Pharmacol.
, vol.69
, pp. 1879-1890
-
-
Wortelboer, H.M.1
Usta, M.2
van Zanden, J.J.3
van Bladeren, P.J.4
Rietjens, I.M.C.M.5
Cnubben, N.H.P.6
-
13
-
-
0026722467
-
Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase
-
Sarkadi B., Price E.M., Boucher R.C., Germann U.A., and Scarborough G.A. Expression of the human multidrug resistance cDNA in insect cells generates a high activity drug-stimulated membrane ATPase. J. Biol. Chem. 267 (1992) 4854-4858
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 4854-4858
-
-
Sarkadi, B.1
Price, E.M.2
Boucher, R.C.3
Germann, U.A.4
Scarborough, G.A.5
-
14
-
-
0035033774
-
Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids
-
Leslie E.M., Mao Q., Oleschuk C.J., Deeley R.G., and Cole S.P.C. Modulation of multidrug resistance protein 1 (MRP1/ABCC1) transport and ATPase activities by interaction with dietary flavonoids. Mol. Pharmacol. 59 (2001) 1171-1180
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1171-1180
-
-
Leslie, E.M.1
Mao, Q.2
Oleschuk, C.J.3
Deeley, R.G.4
Cole, S.P.C.5
-
15
-
-
9144237410
-
Drug interactions with herbal products and grapefruit juice: a conference report
-
Huang S.-M., Hall S.D., Watkins P., Love L.A., Serabjit-Singh C., Betz J.M., Hoffman F.A., Honig P., Coates P.M., Bull J., Chen S.T., Kearns G.L., and Murray M.D. Drug interactions with herbal products and grapefruit juice: a conference report. Clin. Pharmacol. Ther. 75 (2004) 1-12
-
(2004)
Clin. Pharmacol. Ther.
, vol.75
, pp. 1-12
-
-
Huang, S.-M.1
Hall, S.D.2
Watkins, P.3
Love, L.A.4
Serabjit-Singh, C.5
Betz, J.M.6
Hoffman, F.A.7
Honig, P.8
Coates, P.M.9
Bull, J.10
Chen, S.T.11
Kearns, G.L.12
Murray, M.D.13
-
16
-
-
4344602767
-
Inhibition of P-glycoprotein function by tea catechins in KB-C2 cells
-
Kitagawa S., Nabekura T., and Kamiyama S. Inhibition of P-glycoprotein function by tea catechins in KB-C2 cells. J. Pharm. Pharmacol. 56 (2004) 1001-1005
-
(2004)
J. Pharm. Pharmacol.
, vol.56
, pp. 1001-1005
-
-
Kitagawa, S.1
Nabekura, T.2
Kamiyama, S.3
-
17
-
-
35349005744
-
Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells
-
Kitagawa S., Takahashi T., Nabekura T., Tachikawa E., and Hasegawa H. Inhibitory effects of ginsenosides and their hydrolyzed metabolites on daunorubicin transport in KB-C2 cells. Biol. Pharm. Bull. 30 (2007) 1979-1981
-
(2007)
Biol. Pharm. Bull.
, vol.30
, pp. 1979-1981
-
-
Kitagawa, S.1
Takahashi, T.2
Nabekura, T.3
Tachikawa, E.4
Hasegawa, H.5
-
18
-
-
0037164703
-
Functional analysis of candidate ABC transporter proteins for sitosterol transport
-
Albrecht C., I Elliot J., Sardini A., Litman T., Stieger B., Meier P.J., and Higgins C.F. Functional analysis of candidate ABC transporter proteins for sitosterol transport. Biochem. Biophys. Acta 1567 (2002) 133-142
-
(2002)
Biochem. Biophys. Acta
, vol.1567
, pp. 133-142
-
-
Albrecht, C.1
I Elliot, J.2
Sardini, A.3
Litman, T.4
Stieger, B.5
Meier, P.J.6
Higgins, C.F.7
-
19
-
-
0023879927
-
Gum guggul (Commiphora mukul)-the success story of an ancient insight to a modern discovery
-
Satyavati G.V. Gum guggul (Commiphora mukul)-the success story of an ancient insight to a modern discovery. Indian J. Med. Res. 87 (1988) 327-335
-
(1988)
Indian J. Med. Res.
, vol.87
, pp. 327-335
-
-
Satyavati, G.V.1
-
20
-
-
0042130513
-
Guggulipid: a natural cholesterol-lowering agent
-
Urizar N.L., and Moore D.D. Guggulipid: a natural cholesterol-lowering agent. Annu. Rev. Nutr. 23 (2003) 303-313
-
(2003)
Annu. Rev. Nutr.
, vol.23
, pp. 303-313
-
-
Urizar, N.L.1
Moore, D.D.2
-
21
-
-
0042160272
-
Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial
-
Szapary P.O., Wolfe M.L., Bloedon L.T., Cucchiara A.J., DerMarderosian A.H., Cirigliano M.D., and Rader D.J. Guggulipid for the treatment of hypercholesterolemia: a randomized controlled trial. JAMA 290 (2003) 765-772
-
(2003)
JAMA
, vol.290
, pp. 765-772
-
-
Szapary, P.O.1
Wolfe, M.L.2
Bloedon, L.T.3
Cucchiara, A.J.4
DerMarderosian, A.H.5
Cirigliano, M.D.6
Rader, D.J.7
-
22
-
-
0037205046
-
A natural product that lowers cholesterol as an antagonist ligand for FXR
-
Urizar N.L., Liverman A.B., Dodds D.T., Silva F.V., Ordentlich P., Yan Y., Gonzalez F.J., Heyman R.A., Mangelsdorf D.J., and Moore D.D. A natural product that lowers cholesterol as an antagonist ligand for FXR. Science 296 (2002) 1703-1706
-
(2002)
Science
, vol.296
, pp. 1703-1706
-
-
Urizar, N.L.1
Liverman, A.B.2
Dodds, D.T.3
Silva, F.V.4
Ordentlich, P.5
Yan, Y.6
Gonzalez, F.J.7
Heyman, R.A.8
Mangelsdorf, D.J.9
Moore, D.D.10
-
23
-
-
0003295132
-
Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump
-
Cui J., Huang L., Zhao A., Lew J.L., Yu J., Sahoo S., Meinke P.T., Royo I., Pelaez F., and Wright S.D. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump. J. Biol. Chem. 278 (2003) 10214-10220
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10214-10220
-
-
Cui, J.1
Huang, L.2
Zhao, A.3
Lew, J.L.4
Yu, J.5
Sahoo, S.6
Meinke, P.T.7
Royo, I.8
Pelaez, F.9
Wright, S.D.10
-
24
-
-
3342977959
-
Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor
-
Brobst D.E., Ding X., Creech K.L., Goodwin B., Kelley B., and Staudinger J.L. Guggulsterone activates multiple nuclear receptors and induces CYP3A gene expression through the pregnane X receptor. J. Pharmacol. Exp. Ther. 310 (2004) 528-535
-
(2004)
J. Pharmacol. Exp. Ther.
, vol.310
, pp. 528-535
-
-
Brobst, D.E.1
Ding, X.2
Creech, K.L.3
Goodwin, B.4
Kelley, B.5
Staudinger, J.L.6
-
25
-
-
20144369215
-
The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand
-
Burris T.P., Montrose C., Houck K.A., Osborne H.E., Bocchinfuso W.P., Yaden B.C., Cheng C.C., Zink R.W., Barr R.J., Hepler C.D., Krishnan V., Bullock H.A., L Burris L., Galvin R.J., Bramlett K., and Stayrook K.R. The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand. Mol. Pharmacol. 67 (2005) 948-954
-
(2005)
Mol. Pharmacol.
, vol.67
, pp. 948-954
-
-
Burris, T.P.1
Montrose, C.2
Houck, K.A.3
Osborne, H.E.4
Bocchinfuso, W.P.5
Yaden, B.C.6
Cheng, C.C.7
Zink, R.W.8
Barr, R.J.9
Hepler, C.D.10
Krishnan, V.11
Bullock, H.A.12
L Burris, L.13
Galvin, R.J.14
Bramlett, K.15
Stayrook, K.R.16
-
26
-
-
34247349605
-
Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs
-
Urquhart B.L., Tirona R.G., and Kim R.B. Nuclear receptors and the regulation of drug-metabolizing enzymes and drug transporters: implications for interindividual variability in response to drugs. J. Clin. Pharmacol. 47 (2007) 566-578
-
(2007)
J. Clin. Pharmacol.
, vol.47
, pp. 566-578
-
-
Urquhart, B.L.1
Tirona, R.G.2
Kim, R.B.3
|