-
1
-
-
0035434048
-
Insulin production by human embryonic stem cells
-
Assady S, Maor G, Amit M, Itskovitz-Eldor J, Skorecki KL, Tzukerman M, (2001) Insulin production by human embryonic stem cells. Diabetes 50: 1691-1697
-
(2001)
Diabetes
, vol.50
, pp. 1691-1697
-
-
Assady, S.1
Maor, G.2
Amit, M.3
Itskovitz-Eldor, J.4
Skorecki, K.L.5
Tzukerman, M.6
-
2
-
-
56349114812
-
Extracellular matrix as a biological scaffold material: Structure and function
-
Badylak SF, Freytes DO, Gilbert TW, (2009) Extracellular matrix as a biological scaffold material: structure and function. Acta Biomater 5: 1-13
-
(2009)
Acta Biomater
, vol.5
, pp. 1-13
-
-
Badylak, S.F.1
Freytes, D.O.2
Gilbert, T.W.3
-
3
-
-
79960351640
-
Whole-organ tissue engineering: Decellularization and recellularization of three-dimensional matrix scaffolds
-
Badylak SF, Taylor D, Uygun K, (2011) Whole-organ tissue engineering: decellularization and recellularization of three-dimensional matrix scaffolds. Annu Rev Biomed Eng 13: 27-53
-
(2011)
Annu Rev Biomed Eng
, vol.13
, pp. 27-53
-
-
Badylak, S.F.1
Taylor, D.2
Uygun, K.3
-
4
-
-
80052157957
-
Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors
-
Ban H, Nishishita N, Fusaki N, Tabata T, Saeki K, Shikamura M, Takada N, Inoue M, Hasegawa M, Kawamata S, Nishikawa S, (2011) Efficient generation of transgene-free human induced pluripotent stem cells (iPSCs) by temperature-sensitive Sendai virus vectors. Proc Natl Acad Sci USA 108: 14234-14239
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 14234-14239
-
-
Ban, H.1
Nishishita, N.2
Fusaki, N.3
Tabata, T.4
Saeki, K.5
Shikamura, M.6
Takada, N.7
Inoue, M.8
Hasegawa, M.9
Kawamata, S.10
Nishikawa, S.11
-
5
-
-
84872162891
-
Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus
-
Barcala Tabarrozzi AE, Castro CN, Dewey RA, Sogayar MC, Labriola L, Perone MJ, (2013) Cell-based interventions to halt autoimmunity in type 1 diabetes mellitus. Clin Exp Immunol 171: 135-146
-
(2013)
Clin Exp Immunol
, vol.171
, pp. 135-146
-
-
Barcala Tabarrozzi, A.E.1
Castro, C.N.2
Dewey, R.A.3
Sogayar, M.C.4
Labriola, L.5
Perone, M.J.6
-
6
-
-
79959992876
-
Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells
-
Bar-Nur O, Russ HA, Efrat S, Benvenisty N, (2011) Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell 9: 17-23
-
(2011)
Cell Stem Cell
, vol.9
, pp. 17-23
-
-
Bar-Nur, O.1
Russ, H.A.2
Efrat, S.3
Benvenisty, N.4
-
7
-
-
80655144735
-
Cytokines tumor necrosis factor-alpha and interferon-gamma induce pancreatic beta-cell apoptosis through STAT1-mediated Bim protein activation
-
Barthson J, Germano CM, Moore F, Maida A, Drucker DJ, Marchetti P, Gysemans C, Mathieu C, Nuñez G, Jurisicova A, Eizirik DL, Gurzov EN, (2011) Cytokines tumor necrosis factor-alpha and interferon-gamma induce pancreatic beta-cell apoptosis through STAT1-mediated Bim protein activation. J Biol Chem 286: 39632-39643
-
(2011)
J Biol Chem
, vol.286
, pp. 39632-39643
-
-
Barthson, J.1
Germano, C.M.2
Moore, F.3
Maida, A.4
Drucker, D.J.5
Marchetti, P.6
Gysemans, C.7
Mathieu, C.8
Nuñez, G.9
Jurisicova, A.10
Eizirik, D.L.11
Gurzov, E.N.12
-
8
-
-
84901001448
-
Human xenografts are not rejected in a naturally occurring immunodeficient porcine line: A human tumor model in pigs
-
Basel MT, Balivada S, Beck AP, Kerrigan MA, Pyle MM, Dekkers JC, Wyatt CR, Rowland RR, Anderson DE, Bossmann SH, Troyer DL, (2012) Human xenografts are not rejected in a naturally occurring immunodeficient porcine line: a human tumor model in pigs. BioRes Open Access 1: 63-68
-
(2012)
BioRes Open Access
, vol.1
, pp. 63-68
-
-
Basel, M.T.1
Balivada, S.2
Beck, A.P.3
Kerrigan, M.A.4
Pyle, M.M.5
Dekkers, J.C.6
Wyatt, C.R.7
Rowland, R.R.8
Anderson, D.E.9
Bossmann, S.H.10
Troyer, D.L.11
-
9
-
-
84861851646
-
Prevention of autoimmune diabetes by ectopic pancreatic beta-cell expression of interleukin-35
-
Bettini M, Castellaw AH, Lennon GP, Burton AR, Vignali DA, (2012) Prevention of autoimmune diabetes by ectopic pancreatic beta-cell expression of interleukin-35. Diabetes 61: 1519-1526
-
(2012)
Diabetes
, vol.61
, pp. 1519-1526
-
-
Bettini, M.1
Castellaw, A.H.2
Lennon, G.P.3
Burton, A.R.4
Vignali, D.A.5
-
10
-
-
84910651421
-
Insulin-like growth factor-1 stimulates regulatory T cells and suppresses autoimmune disease
-
Bilbao D, Luciani L, Johannesson B, Piszczek A, Rosenthal N, (2014) Insulin-like growth factor-1 stimulates regulatory T cells and suppresses autoimmune disease. EMBO Mol Med 6: 1423-1435
-
(2014)
EMBO Mol Med
, vol.6
, pp. 1423-1435
-
-
Bilbao, D.1
Luciani, L.2
Johannesson, B.3
Piszczek, A.4
Rosenthal, N.5
-
11
-
-
84903639116
-
FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures
-
Bouchi R, Foo KS, Hua H, Tsuchiya K, Ohmura Y, Sandoval PR, Ratner LE, Egli D, Leibel RL, Accili D, (2014) FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures. Nat Commun 5: 4242
-
(2014)
Nat Commun
, vol.5
, pp. 4242
-
-
Bouchi, R.1
Foo, K.S.2
Hua, H.3
Tsuchiya, K.4
Ohmura, Y.5
Sandoval, P.R.6
Ratner, L.E.7
Egli, D.8
Leibel, R.L.9
Accili, D.10
-
12
-
-
84878974216
-
Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice
-
Brehm MA, Powers AC, Shultz LD, Greiner DL, (2012) Advancing animal models of human type 1 diabetes by engraftment of functional human tissues in immunodeficient mice. Cold Spring Harb Perspect Med 2: a007757
-
(2012)
Cold Spring Harb Perspect Med
, vol.2
, pp. a007757
-
-
Brehm, M.A.1
Powers, A.C.2
Shultz, L.D.3
Greiner, D.L.4
-
13
-
-
84867840695
-
Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche
-
Brizzi MF, Tarone G, Defilippi P, (2012) Extracellular matrix, integrins, and growth factors as tailors of the stem cell niche. Curr Opin Cell Biol 24: 645-651
-
(2012)
Curr Opin Cell Biol
, vol.24
, pp. 645-651
-
-
Brizzi, M.F.1
Tarone, G.2
Defilippi, P.3
-
14
-
-
84903279290
-
Islet cell transplantation for the treatment of type 1 diabetes: Recent advances and future challenges
-
Bruni A, Gala-Lopez B, Pepper AR, Abualhassan NS, Shapiro AJ, (2014) Islet cell transplantation for the treatment of type 1 diabetes: recent advances and future challenges. Diabetes Metab Syndr Obes 7: 211-223
-
(2014)
Diabetes Metab Syndr Obes
, vol.7
, pp. 211-223
-
-
Bruni, A.1
Gala-Lopez, B.2
Pepper, A.R.3
Abualhassan, N.S.4
Shapiro, A.J.5
-
15
-
-
77955380678
-
Human antigen-specific regulatory T cells generated by T cell receptor gene transfer
-
Brusko TM, Koya RC, Zhu S, Lee MR, Putnam AL, McClymont SA, Nishimura MI, Han S, Chang LJ, Atkinson MA, Ribas A, Bluestone JA, (2010) Human antigen-specific regulatory T cells generated by T cell receptor gene transfer. PLoS ONE 5: e11726
-
(2010)
PLoS ONE
, vol.5
, pp. e11726
-
-
Brusko, T.M.1
Koya, R.C.2
Zhu, S.3
Lee, M.R.4
Putnam, A.L.5
McClymont, S.A.6
Nishimura, M.I.7
Han, S.8
Chang, L.J.9
Atkinson, M.A.10
Ribas, A.11
Bluestone, J.A.12
-
16
-
-
34848851427
-
Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis
-
Butler AE, Galasso R, Meier JJ, Basu R, Rizza RA, Butler PC, (2007) Modestly increased beta cell apoptosis but no increased beta cell replication in recent-onset type 1 diabetic patients who died of diabetic ketoacidosis. Diabetologia 50: 2323-2331
-
(2007)
Diabetologia
, vol.50
, pp. 2323-2331
-
-
Butler, A.E.1
Galasso, R.2
Meier, J.J.3
Basu, R.4
Rizza, R.A.5
Butler, P.C.6
-
17
-
-
84902664268
-
Immunology. Teaching the immune system "self" respect and tolerance
-
Chatenoud L, (2014) Immunology. Teaching the immune system "self" respect and tolerance. Science 344: 1343-1344
-
(2014)
Science
, vol.344
, pp. 1343-1344
-
-
Chatenoud, L.1
-
18
-
-
84897030116
-
De novo formation of insulin-producing "neo-beta cell islets" from intestinal crypts
-
Chen YJ, Finkbeiner SR, Weinblatt D, Emmett MJ, Tameire F, Yousefi M, Yang C, Maehr R, Zhou Q, Shemer R, Dor Y, Li C, Spence JR, Stanger BZ, (2014) De novo formation of insulin-producing "neo-beta cell islets" from intestinal crypts. Cell Rep 6: 1046-1058
-
(2014)
Cell Rep
, vol.6
, pp. 1046-1058
-
-
Chen, Y.J.1
Finkbeiner, S.R.2
Weinblatt, D.3
Emmett, M.J.4
Tameire, F.5
Yousefi, M.6
Yang, C.7
Maehr, R.8
Zhou, Q.9
Shemer, R.10
Dor, Y.11
Li, C.12
Spence, J.R.13
Stanger, B.Z.14
-
19
-
-
79960649572
-
Matrix components and scaffolds for sustained islet function
-
Cheng JYC, Raghunath M, Whitelock J, Poole-Warren L, (2011) Matrix components and scaffolds for sustained islet function. Tissue Eng Part B Rev 17: 235-247
-
(2011)
Tissue Eng Part B Rev
, vol.17
, pp. 235-247
-
-
Cheng, J.Y.C.1
Raghunath, M.2
Whitelock, J.3
Poole-Warren, L.4
-
20
-
-
37349034589
-
Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells
-
Cho YM, Lim JM, Yoo DH, Kim JH, Chung SS, Park SG, Kim TH, Oh SK, Choi YM, Moon SY, Park KS, Lee HK, (2008) Betacellulin and nicotinamide sustain PDX1 expression and induce pancreatic beta-cell differentiation in human embryonic stem cells. Biochem Biophys Res Commun 366: 129-134
-
(2008)
Biochem Biophys Res Commun
, vol.366
, pp. 129-134
-
-
Cho, Y.M.1
Lim, J.M.2
Yoo, D.H.3
Kim, J.H.4
Chung, S.S.5
Park, S.G.6
Kim, T.H.7
Oh, S.K.8
Choi, Y.M.9
Moon, S.Y.10
Park, K.S.11
Lee, H.K.12
-
21
-
-
84902181362
-
Human somatic cell nuclear transfer using adult cells
-
Chung YG, Eum JH, Lee JE, Shim SH, Sepilian V, Hong SW, Lee Y, Treff NR, Choi YH, Kimbrel EA, Dittman RE, Lanza R, Lee DR, (2014) Human somatic cell nuclear transfer using adult cells. Cell Stem Cell 14: 777-780
-
(2014)
Cell Stem Cell
, vol.14
, pp. 777-780
-
-
Chung, Y.G.1
Eum, J.H.2
Lee, J.E.3
Shim, S.H.4
Sepilian, V.5
Hong, S.W.6
Lee, Y.7
Treff, N.R.8
Choi, Y.H.9
Kimbrel, E.A.10
Dittman, R.E.11
Lanza, R.12
Lee, D.R.13
-
23
-
-
84891762344
-
It's time to bring dendritic cell therapy to type 1 diabetes
-
Creusot RJ, Giannoukakis N, Trucco M, Clare-Salzler MJ, Fathman CG, (2014) It's time to bring dendritic cell therapy to type 1 diabetes. Diabetes 63: 20-30
-
(2014)
Diabetes
, vol.63
, pp. 20-30
-
-
Creusot, R.J.1
Giannoukakis, N.2
Trucco, M.3
Clare-Salzler, M.J.4
Fathman, C.G.5
-
24
-
-
28644448149
-
Efficient differentiation of human embryonic stem cells to definitive endoderm
-
D'Amour KA, Agulnick AD, Eliazer S, Kelly OG, Kroon E, Baetge EE, (2005) Efficient differentiation of human embryonic stem cells to definitive endoderm. Nat Biotechnol 23: 1534-1541
-
(2005)
Nat Biotechnol
, vol.23
, pp. 1534-1541
-
-
D'Amour, K.A.1
Agulnick, A.D.2
Eliazer, S.3
Kelly, O.G.4
Kroon, E.5
Baetge, E.E.6
-
25
-
-
33750846133
-
Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells
-
D'Amour KA, Bang AG, Eliazer S, Kelly OG, Agulnick AD, Smart NG, Moorman MA, Kroon E, Carpenter MK, Baetge EE, (2006) Production of pancreatic hormone-expressing endocrine cells from human embryonic stem cells. Nat Biotechnol 24: 1392-1401
-
(2006)
Nat Biotechnol
, vol.24
, pp. 1392-1401
-
-
D'Amour, K.A.1
Bang, A.G.2
Eliazer, S.3
Kelly, O.G.4
Agulnick, A.D.5
Smart, N.G.6
Moorman, M.A.7
Kroon, E.8
Carpenter, M.K.9
Baetge, E.E.10
-
26
-
-
78650302437
-
Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds
-
Daoud JT, Petropavlovskaia MS, Patapas JM, Degrandpré CE, Diraddo RW, Rosenberg L, Tabrizian M, (2011) Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds. Biomaterials 32: 1536-1542
-
(2011)
Biomaterials
, vol.32
, pp. 1536-1542
-
-
Daoud, J.T.1
Petropavlovskaia, M.S.2
Patapas, J.M.3
Degrandpré, C.E.4
Diraddo, R.W.5
Rosenberg, L.6
Tabrizian, M.7
-
27
-
-
0027370108
-
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group
-
DCCT-Research-Group.
-
DCCT-Research-Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group. N Engl J Med 329: 977-986
-
(1993)
N Engl J Med
, vol.329
, pp. 977-986
-
-
-
28
-
-
33847629171
-
Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes
-
Di Lorenzo TP, Peakman M, Roep BO, (2007) Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes. Clin Exp Immunol 148: 1-16
-
(2007)
Clin Exp Immunol
, vol.148
, pp. 1-16
-
-
Di Lorenzo, T.P.1
Peakman, M.2
Roep, B.O.3
-
30
-
-
28244435870
-
WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells
-
Fonseca SG, Fukuma M, Lipson KL, Nguyen LX, Allen JR, Oka Y, Urano F, (2005) WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells. J Biol Chem 280: 39609-39615
-
(2005)
J Biol Chem
, vol.280
, pp. 39609-39615
-
-
Fonseca, S.G.1
Fukuma, M.2
Lipson, K.L.3
Nguyen, L.X.4
Allen, J.R.5
Oka, Y.6
Urano, F.7
-
31
-
-
0032506750
-
Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis
-
Gallichan WS, Kafri T, Krahl T, Verma IM, Sarvetnick N, (1998) Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis. Hum Gene Ther 9: 2717-2726
-
(1998)
Hum Gene Ther
, vol.9
, pp. 2717-2726
-
-
Gallichan, W.S.1
Kafri, T.2
Krahl, T.3
Verma, I.M.4
Sarvetnick, N.5
-
32
-
-
84856094049
-
Phase i (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients
-
Giannoukakis N, Phillips B, Finegold D, Harnaha J, Trucco M, (2011) Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care 34: 2026-2032
-
(2011)
Diabetes Care
, vol.34
, pp. 2026-2032
-
-
Giannoukakis, N.1
Phillips, B.2
Finegold, D.3
Harnaha, J.4
Trucco, M.5
-
33
-
-
58549093915
-
Developmental biology of the pancreas: A comprehensive review
-
Gittes GK, (2009) Developmental biology of the pancreas: a comprehensive review. Dev Biol 326: 4-35
-
(2009)
Dev Biol
, vol.326
, pp. 4-35
-
-
Gittes, G.K.1
-
34
-
-
84879459481
-
Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering
-
Goh SK, Bertera S, Olsen P, Candiello JE, Halfter W, Uechi G, Balasubramani M, Johnson SA, Sicari BM, Kollar E, Badylak SF, Banerjee I, (2013) Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering. Biomaterials 34: 6760-6772
-
(2013)
Biomaterials
, vol.34
, pp. 6760-6772
-
-
Goh, S.K.1
Bertera, S.2
Olsen, P.3
Candiello, J.E.4
Halfter, W.5
Uechi, G.6
Balasubramani, M.7
Johnson, S.A.8
Sicari, B.M.9
Kollar, E.10
Badylak, S.F.11
Banerjee, I.12
-
35
-
-
79952258224
-
Somatic coding mutations in human induced pluripotent stem cells
-
Gore A, Li Z, Fung HL, Young JE, Agarwal S, Antosiewicz-Bourget J, Canto I, Giorgetti A, Israel MA, Kiskinis E, Lee JH, Loh YH, Manos PD, Montserrat N, Panopoulos AD, Ruiz S, Wilbert ML, Yu J, Kirkness EF, Izpisua Belmonte JC, et al, (2011) Somatic coding mutations in human induced pluripotent stem cells. Nature 471: 63-67
-
(2011)
Nature
, vol.471
, pp. 63-67
-
-
Gore, A.1
Li, Z.2
Fung, H.L.3
Young, J.E.4
Agarwal, S.5
Antosiewicz-Bourget, J.6
Canto, I.7
Giorgetti, A.8
Israel, M.A.9
Kiskinis, E.10
Lee, J.H.11
Loh, Y.H.12
Manos, P.D.13
Montserrat, N.14
Panopoulos, A.D.15
Ruiz, S.16
Wilbert, M.L.17
Yu, J.18
Kirkness, E.F.19
Izpisua, B.J.20
more..
-
36
-
-
84885617460
-
Artificial three-dimensional niches deconstruct pancreas development in vitro
-
Greggio C, De Franceschi F, Figueiredo-Larsen M, Gobaa S, Ranga A, Semb H, Lutolf M, Grapin-Botton A, (2013) Artificial three-dimensional niches deconstruct pancreas development in vitro. Development 140: 4452-4462
-
(2013)
Development
, vol.140
, pp. 4452-4462
-
-
Greggio, C.1
De Franceschi, F.2
Figueiredo-Larsen, M.3
Gobaa, S.4
Ranga, A.5
Semb, H.6
Lutolf, M.7
Grapin-Botton, A.8
-
37
-
-
84855229779
-
Humanized mice for the study of type 1 and type 2 diabetes
-
Greiner DL, Brehm MA, Hosur V, Harlan DM, Powers AC, Shultz LD, (2011) Humanized mice for the study of type 1 and type 2 diabetes. Ann N Y Acad Sci 1245: 55-58
-
(2011)
Ann N y Acad Sci
, vol.1245
, pp. 55-58
-
-
Greiner, D.L.1
Brehm, M.A.2
Hosur, V.3
Harlan, D.M.4
Powers, A.C.5
Shultz, L.D.6
-
38
-
-
80055088071
-
2011 update on pancreas transplantation: Comprehensive trend analysis of 25,000 cases followed up over the course of twenty-four years at the International Pancreas Transplant Registry (IPTR)
-
Gruessner AC, (2011) 2011 update on pancreas transplantation: comprehensive trend analysis of 25,000 cases followed up over the course of twenty-four years at the International Pancreas Transplant Registry (IPTR). Rev Diabet Stud 8: 6-16
-
(2011)
Rev Diabet Stud
, vol.8
, pp. 6-16
-
-
Gruessner, A.C.1
-
39
-
-
33845445620
-
Permanent, lowered HLA class i expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes
-
Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Kruse CA, Mendez R, Stripecke R, Kasahara N, Cicciarelli JC, (2006) Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: averting cytotoxicity by alloreactive T lymphocytes. Transpl Proc 38: 3184-3188
-
(2006)
Transpl Proc
, vol.38
, pp. 3184-3188
-
-
Haga, K.1
Lemp, N.A.2
Logg, C.R.3
Nagashima, J.4
Faure-Kumar, E.5
Gomez, G.G.6
Kruse, C.A.7
Mendez, R.8
Stripecke, R.9
Kasahara, N.10
Cicciarelli, J.C.11
-
40
-
-
84887625676
-
Low-dose interleukin 2 in patients with type 1 diabetes: A phase 1/2 randomised, double-blind, placebo-controlled trial
-
Hartemann A, Bensimon G, Payan CA, Jacqueminet S, Bourron O, Nicolas N, Fonfrede M, Rosenzwajg M, Bernard C, Klatzmann D, (2013) Low-dose interleukin 2 in patients with type 1 diabetes: a phase 1/2 randomised, double-blind, placebo-controlled trial. Lancet Diabetes Endocrinol 1: 295-305
-
(2013)
Lancet Diabetes Endocrinol
, vol.1
, pp. 295-305
-
-
Hartemann, A.1
Bensimon, G.2
Payan, C.A.3
Jacqueminet, S.4
Bourron, O.5
Nicolas, N.6
Fonfrede, M.7
Rosenzwajg, M.8
Bernard, C.9
Klatzmann, D.10
-
41
-
-
0024598735
-
Enhancement of pancreatic islet cell monolayer growth by endothelial cell matrix and insulin
-
Hayek A, Lopez AD, Beattie GM, (1989) Enhancement of pancreatic islet cell monolayer growth by endothelial cell matrix and insulin. In vitro Cell Dev Biol 25: 146-150
-
(1989)
Vitro Cell Dev Biol
, vol.25
, pp. 146-150
-
-
Hayek, A.1
Lopez, A.D.2
Beattie, G.M.3
-
42
-
-
0037198420
-
Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
-
Herold KC, Hagopian W, Auger JA, Poumian-Ruiz E, Taylor L, Donaldson D, Gitelman SE, Harlan DM, Xu D, Zivin RA, Bluestone JA, (2002) Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus. N Engl J Med 346: 1692-1698
-
(2002)
N Engl J Med
, vol.346
, pp. 1692-1698
-
-
Herold, K.C.1
Hagopian, W.2
Auger, J.A.3
Poumian-Ruiz, E.4
Taylor, L.5
Donaldson, D.6
Gitelman, S.E.7
Harlan, D.M.8
Xu, D.9
Zivin, R.A.10
Bluestone, J.A.11
-
43
-
-
84875432419
-
Type 1 diabetes: Translating mechanistic observations into effective clinical outcomes
-
Herold KC, Vignali DA, Cooke A, Bluestone JA, (2013) Type 1 diabetes: translating mechanistic observations into effective clinical outcomes. Nat Rev Immunol 13: 243-256
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 243-256
-
-
Herold, K.C.1
Vignali, D.A.2
Cooke, A.3
Bluestone, J.A.4
-
44
-
-
84878117734
-
IPSC-derived beta cells model diabetes due to glucokinase deficiency
-
Hua H, Shang L, Martinez H, Freeby M, Gallagher MP, Ludwig T, Deng L, Greenberg E, Leduc C, Chung WK, Goland R, Leibel RL, Egli D, (2013) iPSC-derived beta cells model diabetes due to glucokinase deficiency. J Clin Invest 123: 3146-3153
-
(2013)
J Clin Invest
, vol.123
, pp. 3146-3153
-
-
Hua, H.1
Shang, L.2
Martinez, H.3
Freeby, M.4
Gallagher, M.P.5
Ludwig, T.6
Deng, L.7
Greenberg, E.8
Leduc, C.9
Chung, W.K.10
Goland, R.11
Leibel, R.L.12
Egli, D.13
-
45
-
-
84885846800
-
Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
-
Huch M, Bonfanti P, Boj SF, Sato T, Loomans CJ, van de Wetering M, Sojoodi M, Li VS, Schuijers J, Gracanin A, Ringnalda F, Begthel H, Hamer K, Mulder J, van Es JH, de Koning E, Vries RG, Heimberg H, Clevers H, (2013) Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis. EMBO J 32: 2708-2721
-
(2013)
EMBO J
, vol.32
, pp. 2708-2721
-
-
Huch, M.1
Bonfanti, P.2
Boj, S.F.3
Sato, T.4
Loomans, C.J.5
Van De Wetering, M.6
Sojoodi, M.7
Li, V.S.8
Schuijers, J.9
Gracanin, A.10
Ringnalda, F.11
Begthel, H.12
Hamer, K.13
Mulder, J.14
Van Es, J.H.15
De Koning, E.16
Vries, R.G.17
Heimberg, H.18
Clevers, H.19
-
46
-
-
18344370780
-
Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells
-
Hugues S, Mougneau E, Ferlin W, Jeske D, Hofman P, Homann D, Beaudoin L, Schrike C, Von Herrath M, Lehuen A, Glaichenhaus N, (2002) Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells. Immunity 16: 169-181
-
(2002)
Immunity
, vol.16
, pp. 169-181
-
-
Hugues, S.1
Mougneau, E.2
Ferlin, W.3
Jeske, D.4
Hofman, P.5
Homann, D.6
Beaudoin, L.7
Schrike, C.8
Von Herrath, M.9
Lehuen, A.10
Glaichenhaus, N.11
-
47
-
-
17344362695
-
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)
-
Inoue H, Tanizawa Y, Wasson J, Behn P, Kalidas K, Bernal-Mizrachi E, Mueckler M, Marshall H, Donis-Keller H, Crock P, Rogers D, Mikuni M, Kumashiro H, Higashi K, Sobue G, Oka Y, Permutt MA, (1998) A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome). Nat Genet 20: 143-148
-
(1998)
Nat Genet
, vol.20
, pp. 143-148
-
-
Inoue, H.1
Tanizawa, Y.2
Wasson, J.3
Behn, P.4
Kalidas, K.5
Bernal-Mizrachi, E.6
Mueckler, M.7
Marshall, H.8
Donis-Keller, H.9
Crock, P.10
Rogers, D.11
Mikuni, M.12
Kumashiro, H.13
Higashi, K.14
Sobue, G.15
Oka, Y.16
Permutt, M.A.17
-
48
-
-
84922637049
-
Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors
-
Johannesson B, Sagi I, Gore A, Paull D, Yamada M, Golan-Lev T, Li Z, LeDuc C, Shen Y, Stern S, Xu N, Ma H, Kang E, Mitalipov S, Sauer MV, Zhang K, Benvenisty N, Egli D, (2014) Comparable frequencies of coding mutations and loss of imprinting in human pluripotent cells derived by nuclear transfer and defined factors. Cell Stem Cell 15: 634-642
-
(2014)
Cell Stem Cell
, vol.15
, pp. 634-642
-
-
Johannesson, B.1
Sagi, I.2
Gore, A.3
Paull, D.4
Yamada, M.5
Golan-Lev, T.6
Li, Z.7
Leduc, C.8
Shen, Y.9
Stern, S.10
Xu, N.11
Ma, H.12
Kang, E.13
Mitalipov, S.14
Sauer, M.V.15
Zhang, K.16
Benvenisty, N.17
Egli, D.18
-
49
-
-
33847217554
-
Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types
-
Johansson KA, Dursun U, Jordan N, Gu G, Beermann F, Gradwohl G, Grapin-Botton A, (2007) Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types. Dev Cell 12: 457-465
-
(2007)
Dev Cell
, vol.12
, pp. 457-465
-
-
Johansson, K.A.1
Dursun, U.2
Jordan, N.3
Gu, G.4
Beermann, F.5
Gradwohl, G.6
Grapin-Botton, A.7
-
50
-
-
0032876395
-
Deficiency of transporter for antigen presentation (TAP) in tumor cells allows evasion of immune surveillance and increases tumorigenesis
-
Johnsen AK, Templeton DJ, Sy M, Harding CV, (1999) Deficiency of transporter for antigen presentation (TAP) in tumor cells allows evasion of immune surveillance and increases tumorigenesis. J Immunol 163: 4224-4231
-
(1999)
J Immunol
, vol.163
, pp. 4224-4231
-
-
Johnsen, A.K.1
Templeton, D.J.2
Sy, M.3
Harding, C.V.4
-
51
-
-
84863380530
-
A model for personalized in vivo analysis of human immune responsiveness
-
Kalscheuer H, Danzl N, Onoe T, Faust T, Winchester R, Goland R, Greenberg E, Spitzer TR, Savage DG, Tahara H, Choi G, Yang YG, Sykes M, (2012) A model for personalized in vivo analysis of human immune responsiveness. Sci Transl Med 4: 125ra130
-
(2012)
Sci Transl Med
, vol.4
, pp. 125ra130
-
-
Kalscheuer, H.1
Danzl, N.2
Onoe, T.3
Faust, T.4
Winchester, R.5
Goland, R.6
Greenberg, E.7
Spitzer, T.R.8
Savage, D.G.9
Tahara, H.10
Choi, G.11
Yang, Y.G.12
Sykes, M.13
-
52
-
-
84903754303
-
In vivo-generated antigen-specific regulatory T cells treat autoimmunity without compromising antibacterial immune response
-
Kasagi S, Zhang P, Che L, Abbatiello B, Maruyama T, Nakatsukasa H, Zanvit P, Jin W, Konkel JE, Chen W, (2014) In vivo-generated antigen-specific regulatory T cells treat autoimmunity without compromising antibacterial immune response. Sci Transl Med 6: 241ra278
-
(2014)
Sci Transl Med
, vol.6
, pp. 241ra278
-
-
Kasagi, S.1
Zhang, P.2
Che, L.3
Abbatiello, B.4
Maruyama, T.5
Nakatsukasa, H.6
Zanvit, P.7
Jin, W.8
Konkel, J.E.9
Chen, W.10
-
53
-
-
79961175124
-
Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells
-
Kelly OG, Chan MY, Martinson LA, Kadoya K, Ostertag TM, Ross KG, Richardson M, Carpenter MK, D'Amour KA, Kroon E, Moorman M, Baetge EE, Bang AG, (2011) Cell-surface markers for the isolation of pancreatic cell types derived from human embryonic stem cells. Nat Biotechnol 29: 750-756
-
(2011)
Nat Biotechnol
, vol.29
, pp. 750-756
-
-
Kelly, O.G.1
Chan, M.Y.2
Martinson, L.A.3
Kadoya, K.4
Ostertag, T.M.5
Ross, K.G.6
Richardson, M.7
Carpenter, M.K.8
D'Amour, K.A.9
Kroon, E.10
Moorman, M.11
Baetge, E.E.12
Bang, A.G.13
-
54
-
-
20544443927
-
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes
-
Keymeulen B, Vandemeulebroucke E, Ziegler AG, Mathieu C, Kaufman L, Hale G, Gorus F, Goldman M, Walter M, Candon S, Schandene L, Crenier L, De Block C, Seigneurin JM, De Pauw P, Pierard D, Weets I, Rebello P, Bird P, Berrie E, (2005) Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med 352: 2598-2608
-
(2005)
N Engl J Med
, vol.352
, pp. 2598-2608
-
-
Keymeulen, B.1
Vandemeulebroucke, E.2
Ziegler, A.G.3
Mathieu, C.4
Kaufman, L.5
Hale, G.6
Gorus, F.7
Goldman, M.8
Walter, M.9
Candon, S.10
Schandene, L.11
Crenier, L.12
De Block, C.13
Seigneurin, J.M.14
De Pauw, P.15
Pierard, D.16
Weets, I.17
Rebello, P.18
Bird, P.19
Berrie, E.20
more..
-
55
-
-
83255177149
-
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
-
Kim K, Zhao R, Doi A, Ng K, Unternaehrer J, Cahan P, Huo H, Loh YH, Aryee MJ, Lensch MW, Li H, Collins JJ, Feinberg AP, Daley GQ, (2011) Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells. Nat Biotechnol 29: 1117-1119
-
(2011)
Nat Biotechnol
, vol.29
, pp. 1117-1119
-
-
Kim, K.1
Zhao, R.2
Doi, A.3
Ng, K.4
Unternaehrer, J.5
Cahan, P.6
Huo, H.7
Loh, Y.H.8
Aryee, M.J.9
Lensch, M.W.10
Li, H.11
Collins, J.J.12
Feinberg, A.P.13
Daley, G.Q.14
-
56
-
-
84898778301
-
A guide to genome engineering with programmable nucleases
-
Kim H, Kim JS, (2014) A guide to genome engineering with programmable nucleases. Nat Rev Genet 15: 321-334
-
(2014)
Nat Rev Genet
, vol.15
, pp. 321-334
-
-
Kim, H.1
Kim, J.S.2
-
57
-
-
0033142804
-
Therapeutic cloning: Needs and prospects
-
Kind A, Colman A, (1999) Therapeutic cloning: needs and prospects. Semin Cell Dev Biol 10: 279-286
-
(1999)
Semin Cell Dev Biol
, vol.10
, pp. 279-286
-
-
Kind, A.1
Colman, A.2
-
58
-
-
38949113134
-
Extent of beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus
-
Klinke DJ II, (2008) Extent of beta cell destruction is important but insufficient to predict the onset of type 1 diabetes mellitus. PLoS ONE 3: e1374
-
(2008)
PLoS ONE
, vol.3
, pp. e1374
-
-
Klinke, I.I.D.J.1
-
59
-
-
84890810447
-
Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells
-
Koyanagi-Aoi M, Ohnuki M, Takahashi K, Okita K, Noma H, Sawamura Y, Teramoto I, Narita M, Sato Y, Ichisaka T, Amano N, Watanabe A, Morizane A, Yamada Y, Sato T, Takahashi J, Yamanaka S, (2013) Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc Natl Acad Sci USA 110: 20569-20574
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 20569-20574
-
-
Koyanagi-Aoi, M.1
Ohnuki, M.2
Takahashi, K.3
Okita, K.4
Noma, H.5
Sawamura, Y.6
Teramoto, I.7
Narita, M.8
Sato, Y.9
Ichisaka, T.10
Amano, N.11
Watanabe, A.12
Morizane, A.13
Yamada, Y.14
Sato, T.15
Takahashi, J.16
Yamanaka, S.17
-
60
-
-
79951660073
-
Integrin {alpha}3, but not {beta}1, regulates islet cell survival and function via PI3K/Akt signaling pathways
-
Krishnamurthy M, Li J, Fellows GF, Rosenberg L, Goodyer CG, Wang R, (2011) Integrin {alpha}3, but not {beta}1, regulates islet cell survival and function via PI3K/Akt signaling pathways. Endocrinology 152: 424-435
-
(2011)
Endocrinology
, vol.152
, pp. 424-435
-
-
Krishnamurthy, M.1
Li, J.2
Fellows, G.F.3
Rosenberg, L.4
Goodyer, C.G.5
Wang, R.6
-
61
-
-
41849151748
-
Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
-
Kroon E, Martinson LA, Kadoya K, Bang AG, Kelly OG, Eliazer S, Young H, Richardson M, Smart NG, Cunningham J, Agulnick AD, D'Amour KA, Carpenter MK, Baetge EE, (2008) Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo. Nat Biotechnol 26: 443-452
-
(2008)
Nat Biotechnol
, vol.26
, pp. 443-452
-
-
Kroon, E.1
Martinson, L.A.2
Kadoya, K.3
Bang, A.G.4
Kelly, O.G.5
Eliazer, S.6
Young, H.7
Richardson, M.8
Smart, N.G.9
Cunningham, J.10
Agulnick, A.D.11
D'Amour, K.A.12
Carpenter, M.K.13
Baetge, E.E.14
-
62
-
-
2342424743
-
Development of definitive endoderm from embryonic stem cells in culture
-
Kubo A, Shinozaki K, Shannon JM, Kouskoff V, Kennedy M, Woo S, Fehling HJ, Keller G, (2004) Development of definitive endoderm from embryonic stem cells in culture. Development 131: 1651-1662
-
(2004)
Development
, vol.131
, pp. 1651-1662
-
-
Kubo, A.1
Shinozaki, K.2
Shannon, J.M.3
Kouskoff, V.4
Kennedy, M.5
Woo, S.6
Fehling, H.J.7
Keller, G.8
-
63
-
-
84856085947
-
Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells
-
Kunisada Y, Tsubooka-Yamazoe N, Shoji M, Hosoya M, (2012) Small molecules induce efficient differentiation into insulin-producing cells from human induced pluripotent stem cells. Stem Cell Res 8: 274-284
-
(2012)
Stem Cell Res
, vol.8
, pp. 274-284
-
-
Kunisada, Y.1
Tsubooka-Yamazoe, N.2
Shoji, M.3
Hosoya, M.4
-
65
-
-
0033608868
-
Xenotransplantation of cells using biodegradable microcapsules
-
Lanza RP, Jackson R, Sullivan A, Ringeling J, McGrath C, Kuhtreiber W, Chick WL, (1999b) Xenotransplantation of cells using biodegradable microcapsules. Transplantation 67: 1105-1111
-
(1999)
Transplantation
, vol.67
, pp. 1105-1111
-
-
Lanza, R.P.1
Jackson, R.2
Sullivan, A.3
Ringeling, J.4
McGrath, C.5
Kuhtreiber, W.6
Chick, W.L.7
-
66
-
-
84900993129
-
Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency
-
Lee K, Kwon DN, Ezashi T, Choi YJ, Park C, Ericsson AC, Brown AN, Samuel MS, Park KW, Walters EM, Kim DY, Kim JH, Franklin CL, Murphy CN, Roberts RM, Prather RS, Kim JH, (2014) Engraftment of human iPS cells and allogeneic porcine cells into pigs with inactivated RAG2 and accompanying severe combined immunodeficiency. Proc Natl Acad Sci USA 111: 7260-7265
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 7260-7265
-
-
Lee, K.1
Kwon, D.N.2
Ezashi, T.3
Choi, Y.J.4
Park, C.5
Ericsson, A.C.6
Brown, A.N.7
Samuel, M.S.8
Park, K.W.9
Walters, E.M.10
Kim, D.Y.11
Kim, J.H.12
Franklin, C.L.13
Murphy, C.N.14
Roberts, R.M.15
Prather, R.S.16
Kim, J.H.17
-
67
-
-
18044371624
-
Encapsulation of islets in rough surface, hydroxymethylated polysulfone capillaries stimulates VEGF release and promotes vascularization after transplantation
-
Lembert N, Wesche J, Petersen P, Doser M, Zschocke P, Becker HD, Ammon HP, (2005) Encapsulation of islets in rough surface, hydroxymethylated polysulfone capillaries stimulates VEGF release and promotes vascularization after transplantation. Cell Transplant 14: 97-108
-
(2005)
Cell Transplant
, vol.14
, pp. 97-108
-
-
Lembert, N.1
Wesche, J.2
Petersen, P.3
Doser, M.4
Zschocke, P.5
Becker, H.D.6
Ammon, H.P.7
-
68
-
-
84865214922
-
Expanding the clinical indications for alpha(1)-antitrypsin therapy
-
Lewis EC, (2012) Expanding the clinical indications for alpha(1)-antitrypsin therapy. Mol Med 18: 957-970
-
(2012)
Mol Med
, vol.18
, pp. 957-970
-
-
Lewis, E.C.1
-
69
-
-
67349268443
-
Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft
-
Liu EH, Digon BJ 3rd, Hirshberg B, Chang R, Wood BJ, Neeman Z, Kam A, Wesley RA, Polly SM, Hofmann RM, Rother KI, Harlan DM, (2009) Pancreatic beta cell function persists in many patients with chronic type 1 diabetes, but is not dramatically improved by prolonged immunosuppression and euglycaemia from a beta cell allograft. Diabetologia 52: 1369-1380
-
(2009)
Diabetologia
, vol.52
, pp. 1369-1380
-
-
Liu, E.H.1
Digon, B.J.2
Hirshberg, B.3
Chang, R.4
Wood, B.J.5
Neeman, Z.6
Kam, A.7
Wesley, R.A.8
Polly, S.M.9
Hofmann, R.M.10
Rother, K.I.11
Harlan, D.M.12
-
70
-
-
0025300414
-
In search of the "missing self": MHC molecules and NK cell recognition
-
Ljunggren HG, Karre K, (1990) In search of the "missing self": MHC molecules and NK cell recognition. Immunol Today 11: 237-244
-
(1990)
Immunol Today
, vol.11
, pp. 237-244
-
-
Ljunggren, H.G.1
Karre, K.2
-
71
-
-
0027272264
-
Long-term culture of human pancreatic islets in an extracellular matrix: Morphological and metabolic effects
-
Lucas-Clerc C, Massart C, Campion JP, Launois B, Nicol M, (1993) Long-term culture of human pancreatic islets in an extracellular matrix: morphological and metabolic effects. Mol Cell Endocrinol 94: 9-20
-
(1993)
Mol Cell Endocrinol
, vol.94
, pp. 9-20
-
-
Lucas-Clerc, C.1
Massart, C.2
Campion, J.P.3
Launois, B.4
Nicol, M.5
-
72
-
-
84880559839
-
Antigen-specific tolerance by autologous myelin peptide-coupled cells: A phase 1 trial in multiple sclerosis
-
Lutterotti A, Yousef S, Sputtek A, Stürner KH, Stellmann JP, Breiden P, Reinhardt S, Schulze C, Bester M, Heesen C, Schippling S, Miller SD, Sospedra M, Martin R, (2013) Antigen-specific tolerance by autologous myelin peptide-coupled cells: a phase 1 trial in multiple sclerosis. Sci Transl Med 5: 188ra175
-
(2013)
Sci Transl Med
, vol.5
, pp. 188ra175
-
-
Lutterotti, A.1
Yousef, S.2
Sputtek, A.3
Stürner, K.H.4
Stellmann, J.P.5
Breiden, P.6
Reinhardt, S.7
Schulze, C.8
Bester, M.9
Heesen, C.10
Schippling, S.11
Miller, S.D.12
Sospedra, M.13
Martin, R.14
-
73
-
-
70349437501
-
Generation of pluripotent stem cells from patients with type 1 diabetes
-
Maehr R, Chen S, Snitow M, Ludwig T, Yagasaki L, Goland R, Leibel RL, Melton DA, (2009) Generation of pluripotent stem cells from patients with type 1 diabetes. Proc Natl Acad Sci USA 106: 15768-15773
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 15768-15773
-
-
Maehr, R.1
Chen, S.2
Snitow, M.3
Ludwig, T.4
Yagasaki, L.5
Goland, R.6
Leibel, R.L.7
Melton, D.A.8
-
74
-
-
77950649733
-
Developing combination immunotherapies for type 1 diabetes: Recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group
-
Group I.-J.T.D.C.T.A.
-
Matthews JB, Staeva TP, Bernstein PL, Peakman M, von Herrath M, Group I.-J.T.D.C.T.A. (2010) Developing combination immunotherapies for type 1 diabetes: recommendations from the ITN-JDRF Type 1 Diabetes Combination Therapy Assessment Group. Clin Exp Immunol 160: 176-184
-
(2010)
Clin Exp Immunol
, vol.160
, pp. 176-184
-
-
Matthews, J.B.1
Staeva, T.P.2
Bernstein, P.L.3
Peakman, M.4
Von Herrath, M.5
-
75
-
-
77956081482
-
Patterning of mono- and multilayered pancreatic beta-cell clusters
-
Mendelsohn AD, Bernards DA, Lowe RD, Desai TA, (2010) Patterning of mono- and multilayered pancreatic beta-cell clusters. Langmuir 26: 9943-9949
-
(2010)
Langmuir
, vol.26
, pp. 9943-9949
-
-
Mendelsohn, A.D.1
Bernards, D.A.2
Lowe, R.D.3
Desai, T.A.4
-
76
-
-
33744947093
-
Current status of pancreatic islet transplantation
-
Merani S, Shapiro AM, (2006) Current status of pancreatic islet transplantation. Clin Sci 110: 611-625
-
(2006)
Clin Sci
, vol.110
, pp. 611-625
-
-
Merani, S.1
Shapiro, A.M.2
-
77
-
-
77952682209
-
Noggin, retinoids, and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells
-
2245 e2231-2214
-
Mfopou JK, Chen B, Mateizel I, Sermon K, Bouwens L, (2010) Noggin, retinoids, and fibroblast growth factor regulate hepatic or pancreatic fate of human embryonic stem cells. Gastroenterology 138: 2233-2245, 2245 e2231-2214
-
(2010)
Gastroenterology
, vol.138
, pp. 2233-2245
-
-
Mfopou, J.K.1
Chen, B.2
Mateizel, I.3
Sermon, K.4
Bouwens, L.5
-
78
-
-
84877601258
-
Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering
-
Mirmalek-Sani SH, Orlando G, McQuilling JP, Pareta R, Mack DL, Salvatori M, Farney AC, Stratta RJ, Atala A, Opara EC, Soker S, (2013) Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering. Biomaterials 34: 5488-5495
-
(2013)
Biomaterials
, vol.34
, pp. 5488-5495
-
-
Mirmalek-Sani, S.H.1
Orlando, G.2
McQuilling, J.P.3
Pareta, R.4
MacK, D.L.5
Salvatori, M.6
Farney, A.C.7
Stratta, R.J.8
Atala, A.9
Opara, E.C.10
Soker, S.11
-
79
-
-
0034859074
-
Evaluation of insulin secretion of isolated rat islets cultured in extracellular matrix
-
Nagata N, Gu Y, Hori H, Balamurugan AN, Touma M, Kawakami Y, Wang W, Baba TT, Satake A, Nozawa M, Tabata Y, Inoue K, (2001) Evaluation of insulin secretion of isolated rat islets cultured in extracellular matrix. Cell Transplant 10: 447-451
-
(2001)
Cell Transplant
, vol.10
, pp. 447-451
-
-
Nagata, N.1
Gu, Y.2
Hori, H.3
Balamurugan, A.N.4
Touma, M.5
Kawakami, Y.6
Wang, W.7
Baba, T.T.8
Satake, A.9
Nozawa, M.10
Tabata, Y.11
Inoue, K.12
-
80
-
-
84891790939
-
Diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: Advances and contributions
-
Group D.E.R.
-
Nathan DM, Bayless M, Cleary P, Genuth S, Gubitosi-Klug R, Lachin JM, Lorenzi G, Zinman B, Group D.E.R. (2013) Diabetes control and complications trial/epidemiology of diabetes interventions and complications study at 30 years: advances and contributions. Diabetes 62: 3976-3986
-
(2013)
Diabetes
, vol.62
, pp. 3976-3986
-
-
Nathan, D.M.1
Bayless, M.2
Cleary, P.3
Genuth, S.4
Gubitosi-Klug, R.5
Lachin, J.M.6
Lorenzi, G.7
Zinman, B.8
-
81
-
-
34848887156
-
Recovery from diabetes in mice by beta cell regeneration
-
Nir T, Melton DA, Dor Y, (2007) Recovery from diabetes in mice by beta cell regeneration. J Clin Invest 117: 2553-2561
-
(2007)
J Clin Invest
, vol.117
, pp. 2553-2561
-
-
Nir, T.1
Melton, D.A.2
Dor, Y.3
-
82
-
-
79957998057
-
DNA methylation dynamics in human induced pluripotent stem cells over time
-
Nishino K, Toyoda M, Yamazaki-Inoue M, Fukawatase Y, Chikazawa E, Sakaguchi H, Akutsu H, Umezawa A, (2011) DNA methylation dynamics in human induced pluripotent stem cells over time. PLoS Genet 7: e1002085-e1002085
-
(2011)
PLoS Genet
, vol.7
, pp. e1002085-e1002085
-
-
Nishino, K.1
Toyoda, M.2
Yamazaki-Inoue, M.3
Fukawatase, Y.4
Chikazawa, E.5
Sakaguchi, H.6
Akutsu, H.7
Umezawa, A.8
-
83
-
-
33645221626
-
Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution
-
Nishio J, Gaglia JL, Turvey SE, Campbell C, Benoist C, Mathis D, (2006) Islet recovery and reversal of murine type 1 diabetes in the absence of any infused spleen cell contribution. Science 311: 1775-1778
-
(2006)
Science
, vol.311
, pp. 1775-1778
-
-
Nishio, J.1
Gaglia, J.L.2
Turvey, S.E.3
Campbell, C.4
Benoist, C.5
Mathis, D.6
-
84
-
-
79551580013
-
Stage-specific signaling through TGFbeta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells
-
Nostro MC, Sarangi F, Ogawa S, Holtzinger A, Corneo B, Li X, Micallef SJ, Park IH, Basford C, Wheeler MB, Daley GQ, Elefanty AG, Stanley EG, Keller G, (2011) Stage-specific signaling through TGFbeta family members and WNT regulates patterning and pancreatic specification of human pluripotent stem cells. Development 138: 861-871
-
(2011)
Development
, vol.138
, pp. 861-871
-
-
Nostro, M.C.1
Sarangi, F.2
Ogawa, S.3
Holtzinger, A.4
Corneo, B.5
Li, X.6
Micallef, S.J.7
Park, I.H.8
Basford, C.9
Wheeler, M.B.10
Daley, G.Q.11
Elefanty, A.G.12
Stanley, E.G.13
Keller, G.14
-
85
-
-
0035114642
-
Long-term culture in matrigel enhances the insulin secretion of fetal porcine islet-like cell clusters in vitro
-
Oberg-Welsh C, (2001) Long-term culture in matrigel enhances the insulin secretion of fetal porcine islet-like cell clusters in vitro. Pancreas 22: 157-163
-
(2001)
Pancreas
, vol.22
, pp. 157-163
-
-
Oberg-Welsh, C.1
-
86
-
-
84859491432
-
Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency
-
Ohmine S, Squillace KA, Hartjes KA, Deeds MC, Armstrong AS, Thatava T, Sakuma T, Terzic A, Kudva Y, Ikeda Y, (2012) Reprogrammed keratinocytes from elderly type 2 diabetes patients suppress senescence genes to acquire induced pluripotency. Aging 4: 60-73
-
(2012)
Aging
, vol.4
, pp. 60-73
-
-
Ohmine, S.1
Squillace, K.A.2
Hartjes, K.A.3
Deeds, M.C.4
Armstrong, A.S.5
Thatava, T.6
Sakuma, T.7
Terzic, A.8
Kudva, Y.9
Ikeda, Y.10
-
87
-
-
84890999355
-
The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells
-
Oram RA, Jones AG, Besser RE, Knight BA, Shields BM, Brown RJ, Hattersley AT, McDonald TJ, (2014) The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells. Diabetologia 57: 187-191
-
(2014)
Diabetologia
, vol.57
, pp. 187-191
-
-
Oram, R.A.1
Jones, A.G.2
Besser, R.E.3
Knight, B.A.4
Shields, B.M.5
Brown, R.J.6
Hattersley, A.T.7
McDonald, T.J.8
-
88
-
-
84899076452
-
Cell replacement strategies aimed at reconstitution of the beta-cell compartment in type 1 diabetes
-
Orlando G, Gianello P, Salvatori M, Stratta RJ, Soker S, Ricordi C, Dominguez-Bendala J, (2014) Cell replacement strategies aimed at reconstitution of the beta-cell compartment in type 1 diabetes. Diabetes 63: 1433-1444
-
(2014)
Diabetes
, vol.63
, pp. 1433-1444
-
-
Orlando, G.1
Gianello, P.2
Salvatori, M.3
Stratta, R.J.4
Soker, S.5
Ricordi, C.6
Dominguez-Bendala, J.7
-
89
-
-
84910673362
-
Generation of functional human pancreatic beta cells in vitro
-
Pagliuca FW, Millman JR, Gurtler M, Segel M, Van Dervort A, Ryu JH, Peterson QP, Greiner D, Melton DA, (2014) Generation of functional human pancreatic beta cells in vitro. Cell 159: 428-439
-
(2014)
Cell
, vol.159
, pp. 428-439
-
-
Pagliuca, F.W.1
Millman, J.R.2
Gurtler, M.3
Segel, M.4
Van Dervort, A.5
Ryu, J.H.6
Peterson, Q.P.7
Greiner, D.8
Melton, D.A.9
-
90
-
-
84881120386
-
Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development
-
Parent AV, Russ HA, Khan IS, LaFlam TN, Metzger TC, Anderson MS, Hebrok M, (2013) Generation of functional thymic epithelium from human embryonic stem cells that supports host T cell development. Cell Stem Cell 13: 219-229
-
(2013)
Cell Stem Cell
, vol.13
, pp. 219-229
-
-
Parent, A.V.1
Russ, H.A.2
Khan, I.S.3
Laflam, T.N.4
Metzger, T.C.5
Anderson, M.S.6
Hebrok, M.7
-
91
-
-
0029951850
-
Insulin release and insulin mRNA levels in rat islets of Langerhans cultured on extracellular matrix
-
Perfetti R, Henderson TE, Wang Y, Montrose-Rafizadeh C, Egan JM, (1996) Insulin release and insulin mRNA levels in rat islets of Langerhans cultured on extracellular matrix. Pancreas 13: 47-54
-
(1996)
Pancreas
, vol.13
, pp. 47-54
-
-
Perfetti, R.1
Henderson, T.E.2
Wang, Y.3
Montrose-Rafizadeh, C.4
Egan, J.M.5
-
92
-
-
84875844455
-
Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes
-
Phelps EA, Headen DM, Taylor WR, Thule PM, Garcia AJ, (2013) Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes. Biomaterials 34: 4602-4611
-
(2013)
Biomaterials
, vol.34
, pp. 4602-4611
-
-
Phelps, E.A.1
Headen, D.M.2
Taylor, W.R.3
Thule, P.M.4
Garcia, A.J.5
-
93
-
-
84879525527
-
Tolerance strategies employing antigen-coupled apoptotic cells and carboxylated PLG nanoparticles for the treatment of type 1 diabetes
-
Prasad S, Xu D, Miller SD, (2012) Tolerance strategies employing antigen-coupled apoptotic cells and carboxylated PLG nanoparticles for the treatment of type 1 diabetes. Rev Diabet Stud 9: 319-327
-
(2012)
Rev Diabet Stud
, vol.9
, pp. 319-327
-
-
Prasad, S.1
Xu, D.2
Miller, S.D.3
-
94
-
-
2542461057
-
PVA hydrogel sheet macroencapsulation for the bioartificial pancreas
-
Qi M, Gu Y, Sakata N, Kim D, Shirouzu Y, Yamamoto C, Hiura A, Sumi S, Inoue K, (2004) PVA hydrogel sheet macroencapsulation for the bioartificial pancreas. Biomaterials 25: 5885-5892
-
(2004)
Biomaterials
, vol.25
, pp. 5885-5892
-
-
Qi, M.1
Gu, Y.2
Sakata, N.3
Kim, D.4
Shirouzu, Y.5
Yamamoto, C.6
Hiura, A.7
Sumi, S.8
Inoue, K.9
-
95
-
-
84926259583
-
Transplantation of encapsulated pancreatic islets as a treatment for patients with type 1 diabetes mellitus
-
Qi M, (2014) Transplantation of encapsulated pancreatic islets as a treatment for patients with type 1 diabetes mellitus. Adv Med 2014: 429710
-
(2014)
Adv Med
, vol.2014
, pp. 429710
-
-
Qi, M.1
-
96
-
-
84875621203
-
Viral interference with antigen presentation: Trapping TAP
-
Ressing ME, Luteijn RD, Horst D, Wiertz EJ, (2013) Viral interference with antigen presentation: trapping TAP. Mol Immunol 55: 139-142
-
(2013)
Mol Immunol
, vol.55
, pp. 139-142
-
-
Ressing, M.E.1
Luteijn, R.D.2
Horst, D.3
Wiertz, E.J.4
-
97
-
-
84864390303
-
Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice
-
Rezania A, Bruin JE, Riedel MJ, Mojibian M, Asadi A, Xu J, Gauvin R, Narayan K, Karanu F, O'Neil JJ, Ao Z, Warnock GL, Kieffer TJ, (2012) Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice. Diabetes 61: 2016-2029
-
(2012)
Diabetes
, vol.61
, pp. 2016-2029
-
-
Rezania, A.1
Bruin, J.E.2
Riedel, M.J.3
Mojibian, M.4
Asadi, A.5
Xu, J.6
Gauvin, R.7
Narayan, K.8
Karanu, F.9
O'Neil, J.J.10
Ao, Z.11
Warnock, G.L.12
Kieffer, T.J.13
-
98
-
-
84887940137
-
Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo
-
Rezania A, Bruin JE, Xu J, Narayan K, Fox JK, O'Neil JJ, Kieffer TJ, (2013) Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo. Stem Cells 31: 2432-2442
-
(2013)
Stem Cells
, vol.31
, pp. 2432-2442
-
-
Rezania, A.1
Bruin, J.E.2
Xu, J.3
Narayan, K.4
Fox, J.K.5
O'Neil, J.J.6
Kieffer, T.J.7
-
99
-
-
84983134468
-
Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
-
Rezania A, Bruin JE, Arora P, Rubin A, Batushansky I, Asadi A, O'Dwyer S, Quiskamp N, Mojibian M, Albrecht T, Yang YH, Johnson JD, Kieffer TJ, (2014) Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells. Nat Biotechnol 32: 1121-1133
-
(2014)
Nat Biotechnol
, vol.32
, pp. 1121-1133
-
-
Rezania, A.1
Bruin, J.E.2
Arora, P.3
Rubin, A.4
Batushansky, I.5
Asadi, A.6
O'Dwyer, S.7
Quiskamp, N.8
Mojibian, M.9
Albrecht, T.10
Yang, Y.H.11
Johnson, J.D.12
Kieffer, T.J.13
-
100
-
-
84856007232
-
The promise of induced pluripotent stem cells in research and therapy
-
Robinton DA, Daley GQ, (2012) The promise of induced pluripotent stem cells in research and therapy. Nature 481: 295-305
-
(2012)
Nature
, vol.481
, pp. 295-305
-
-
Robinton, D.A.1
Daley, G.Q.2
-
101
-
-
10744223421
-
Total pancreatectomy and autologous islet cell transplantation as a means to treat severe chronic pancreatitis
-
Rodriguez Rilo HL, Ahmad SA, D'Alessio D, Iwanaga Y, Kim J, Choe KA, Moulton JS, Martin J, Pennington LJ, Soldano DA, Biliter J, Martin SP, Ulrich CD, Somogyi L, Welge J, Matthews JB, Lowy AM, (2003) Total pancreatectomy and autologous islet cell transplantation as a means to treat severe chronic pancreatitis. J Gastrointest Surg 7: 978-989
-
(2003)
J Gastrointest Surg
, vol.7
, pp. 978-989
-
-
Rodriguez Rilo, H.L.1
Ahmad, S.A.2
D'Alessio, D.3
Iwanaga, Y.4
Kim, J.5
Choe, K.A.6
Moulton, J.S.7
Martin, J.8
Pennington, L.J.9
Soldano, D.A.10
Biliter, J.11
Martin, S.P.12
Ulrich, C.D.13
Somogyi, L.14
Welge, J.15
Matthews, J.B.16
Lowy, A.M.17
-
102
-
-
74549199886
-
Islet inflammation and CXCL10 in recent-onset type 1 diabetes
-
Roep BO, Kleijwegt FS, van Halteren AG, Bonato V, Boggi U, Vendrame F, Marchetti P, Dotta F, (2010) Islet inflammation and CXCL10 in recent-onset type 1 diabetes. Clin Exp Immunol 159: 338-343
-
(2010)
Clin Exp Immunol
, vol.159
, pp. 338-343
-
-
Roep, B.O.1
Kleijwegt, F.S.2
Van Halteren, A.G.3
Bonato, V.4
Boggi, U.5
Vendrame, F.6
Marchetti, P.7
Dotta, F.8
-
103
-
-
84863812951
-
Encapsulated islets transplantation: Past, present and future
-
Sakata N, Sumi S, Yoshimatsu G, Goto M, Egawa S, Unno M, (2012) Encapsulated islets transplantation: past, present and future. World J Gastrointest Pathophysiol 3: 19-26
-
(2012)
World J Gastrointest Pathophysiol
, vol.3
, pp. 19-26
-
-
Sakata, N.1
Sumi, S.2
Yoshimatsu, G.3
Goto, M.4
Egawa, S.5
Unno, M.6
-
104
-
-
0034524101
-
Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas
-
Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M, (2000) Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development 127: 5533-5540
-
(2000)
Development
, vol.127
, pp. 5533-5540
-
-
Sander, M.1
Sussel, L.2
Conners, J.3
Scheel, D.4
Kalamaras, J.5
Dela Cruz, F.6
Schwitzgebel, V.7
Hayes-Jordan, A.8
German, M.9
-
105
-
-
0028111040
-
Protection of encapsulated human islets implanted without immunosuppression in patients with type i or type II diabetes and in nondiabetic control subjects
-
Scharp DW, Swanson CJ, Olack BJ, Latta PP, Hegre OD, Doherty EJ, Gentile FT, Flavin KS, Ansara MF, Lacy PE, (1994) Protection of encapsulated human islets implanted without immunosuppression in patients with type I or type II diabetes and in nondiabetic control subjects. Diabetes 43: 1167-1170
-
(1994)
Diabetes
, vol.43
, pp. 1167-1170
-
-
Scharp, D.W.1
Swanson, C.J.2
Olack, B.J.3
Latta, P.P.4
Hegre, O.D.5
Doherty, E.J.6
Gentile, F.T.7
Flavin, K.S.8
Ansara, M.F.9
Lacy, P.E.10
-
106
-
-
84862059081
-
A scalable system for production of functional pancreatic progenitors from human embryonic stem cells
-
sernova.com.
-
Schulz TC, Young HY, Agulnick AD, Babin MJ, Baetge EE, Bang AG, Bhoumik A, Cepa I, Cesario RM, Haakmeester C, Kadoya K, Kelly JR, Kerr J, Martinson LA, McLean AB, Moorman MA, Payne JK, Richardson M, Ross KG, Sherrer ES, et al, (2012) A scalable system for production of functional pancreatic progenitors from human embryonic stem cells. PLoS ONE 7: e37004 sernova.com.
-
(2012)
PLoS ONE
, vol.7
, pp. e37004
-
-
Schulz, T.C.1
Young, H.Y.2
Agulnick, A.D.3
Babin, M.J.4
Baetge, E.E.5
Bang, A.G.6
Bhoumik, A.7
Cepa, I.8
Cesario, R.M.9
Haakmeester, C.10
Kadoya, K.11
Kelly, J.R.12
Kerr, J.13
Martinson, L.A.14
McLean, A.B.15
Moorman, M.A.16
Payne, J.K.17
Richardson, M.18
Ross, K.G.19
Sherrer, E.S.20
more..
-
107
-
-
84894442406
-
Beta-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome
-
Shang L, Hua H, Foo K, Martinez H, Watanabe K, Zimmer M, Kahler DJ, Freeby M, Chung W, LeDuc C, Goland R, Leibel RL, Egli D, (2014) beta-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome. Diabetes 63: 923-933
-
(2014)
Diabetes
, vol.63
, pp. 923-933
-
-
Shang, L.1
Hua, H.2
Foo, K.3
Martinez, H.4
Watanabe, K.5
Zimmer, M.6
Kahler, D.J.7
Freeby, M.8
Chung, W.9
Leduc, C.10
Goland, R.11
Leibel, R.L.12
Egli, D.13
-
108
-
-
70149123492
-
Transgenic expression of single-chain anti-CTLA-4 Fv on beta cells protects nonobese diabetic mice from autoimmune diabetes
-
Shieh SJ, Chou FC, Yu PN, Lin WC, Chang DM, Roffler SR, Sytwu HK, (2009) Transgenic expression of single-chain anti-CTLA-4 Fv on beta cells protects nonobese diabetic mice from autoimmune diabetes. J Immunol 183: 2277-2285
-
(2009)
J Immunol
, vol.183
, pp. 2277-2285
-
-
Shieh, S.J.1
Chou, F.C.2
Yu, P.N.3
Lin, W.C.4
Chang, D.M.5
Roffler, S.R.6
Sytwu, H.K.7
-
109
-
-
84863088235
-
A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation
-
Shih HP, Kopp JL, Sandhu M, Dubois CL, Seymour PA, Grapin-Botton A, Sander M, (2012) A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation. Development 139: 2488-2499
-
(2012)
Development
, vol.139
, pp. 2488-2499
-
-
Shih, H.P.1
Kopp, J.L.2
Sandhu, M.3
Dubois, C.L.4
Seymour, P.A.5
Grapin-Botton, A.6
Sander, M.7
-
110
-
-
84872018209
-
Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials
-
Staeva TP, Chatenoud L, Insel R, Atkinson MA, (2013) Recent lessons learned from prevention and recent-onset type 1 diabetes immunotherapy trials. Diabetes 62: 9-17
-
(2013)
Diabetes
, vol.62
, pp. 9-17
-
-
Staeva, T.P.1
Chatenoud, L.2
Insel, R.3
Atkinson, M.A.4
-
112
-
-
0036408818
-
Gene transfection and expression of transforming growth factor-beta1 in nonobese diabetic mouse islets protects beta-cells in syngeneic islet grafts from autoimmune destruction
-
Suarez-Pinzon WL, Marcoux Y, Ghahary A, Rabinovitch A, (2002) Gene transfection and expression of transforming growth factor-beta1 in nonobese diabetic mouse islets protects beta-cells in syngeneic islet grafts from autoimmune destruction. Cell Transplant 11: 519-528
-
(2002)
Cell Transplant
, vol.11
, pp. 519-528
-
-
Suarez-Pinzon, W.L.1
Marcoux, Y.2
Ghahary, A.3
Rabinovitch, A.4
-
113
-
-
84884821283
-
Role of BMP signaling in pancreatic progenitor differentiation from human embryonic stem cells
-
Sui L, Geens M, Sermon K, Bouwens L, Mfopou JK, (2013) Role of BMP signaling in pancreatic progenitor differentiation from human embryonic stem cells. Stem Cell Rev 9: 569-577
-
(2013)
Stem Cell Rev
, vol.9
, pp. 569-577
-
-
Sui, L.1
Geens, M.2
Sermon, K.3
Bouwens, L.4
Mfopou, J.K.5
-
114
-
-
84881123537
-
Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo
-
Sun X, Xu J, Lu H, Liu W, Miao Z, Sui X, Liu H, Su L, Du W, He Q, Chen F, Shi Y, Deng H, (2013) Directed differentiation of human embryonic stem cells into thymic epithelial progenitor-like cells reconstitutes the thymic microenvironment in vivo. Cell Stem Cell 13: 230-236
-
(2013)
Cell Stem Cell
, vol.13
, pp. 230-236
-
-
Sun, X.1
Xu, J.2
Lu, H.3
Liu, W.4
Miao, Z.5
Sui, X.6
Liu, H.7
Su, L.8
Du, W.9
He, Q.10
Chen, F.11
Shi, Y.12
Deng, H.13
-
115
-
-
34248193253
-
Immune surveillance of tumors
-
Swann JB, Smyth MJ, (2007) Immune surveillance of tumors. J Clin Invest 117: 1137-1146
-
(2007)
J Clin Invest
, vol.117
, pp. 1137-1146
-
-
Swann, J.B.1
Smyth, M.J.2
-
116
-
-
84878838747
-
Human embryonic stem cells derived by somatic cell nuclear transfer
-
Tachibana M, Amato P, Sparman M, Gutierrez NM, Tippner-Hedges R, Ma H, Kang E, Fulati A, Lee HS, Sritanaudomchai H, Masterson K, Larson J, Eaton D, Sadler-Fredd K, Battaglia D, Lee D, Wu D, Jensen J, Patton P, Gokhale S, et al, (2013) Human embryonic stem cells derived by somatic cell nuclear transfer. Cell 153: 1228-1238
-
(2013)
Cell
, vol.153
, pp. 1228-1238
-
-
Tachibana, M.1
Amato, P.2
Sparman, M.3
Gutierrez, N.M.4
Tippner-Hedges, R.5
Ma, H.6
Kang, E.7
Fulati, A.8
Lee, H.S.9
Sritanaudomchai, H.10
Masterson, K.11
Larson, J.12
Eaton, D.13
Sadler-Fredd, K.14
Battaglia, D.15
Lee, D.16
Wu, D.17
Jensen, J.18
Patton, P.19
Gokhale, S.20
more..
-
117
-
-
36248966518
-
Induction of pluripotent stem cells from adult human fibroblasts by defined factors
-
Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S, (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-872
-
(2007)
Cell
, vol.131
, pp. 861-872
-
-
Takahashi, K.1
Tanabe, K.2
Ohnuki, M.3
Narita, M.4
Ichisaka, T.5
Tomoda, K.6
Yamanaka, S.7
-
118
-
-
84859350525
-
Generation of functional insulin-producing cells in the gut by Foxo1 ablation
-
S401
-
Talchai C, Xuan S, Kitamura T, DePinho RA, Accili D, (2012) Generation of functional insulin-producing cells in the gut by Foxo1 ablation. Nat Genet 44: 406-412, S401
-
(2012)
Nat Genet
, vol.44
, pp. 406-412
-
-
Talchai, C.1
Xuan, S.2
Kitamura, T.3
Depinho, R.A.4
Accili, D.5
-
119
-
-
0042346340
-
Early endoderm development in vertebrates: Lineage differentiation and morphogenetic function
-
Tam PP, Kanai-Azuma M, Kanai Y, (2003) Early endoderm development in vertebrates: lineage differentiation and morphogenetic function. Curr Opin Genet Dev 13: 393-400
-
(2003)
Curr Opin Genet Dev
, vol.13
, pp. 393-400
-
-
Tam, P.P.1
Kanai-Azuma, M.2
Kanai, Y.3
-
120
-
-
84874303834
-
Derivation of human induced pluripotent stem cells from patients with maturity onset diabetes of the young
-
Teo AK, Windmueller R, Johansson BB, Dirice E, Njolstad PR, Tjora E, Raeder H, Kulkarni RN, (2013) Derivation of human induced pluripotent stem cells from patients with maturity onset diabetes of the young. J Biol Chem 288: 5353-5356
-
(2013)
J Biol Chem
, vol.288
, pp. 5353-5356
-
-
Teo, A.K.1
Windmueller, R.2
Johansson, B.B.3
Dirice, E.4
Njolstad, P.R.5
Tjora, E.6
Raeder, H.7
Kulkarni, R.N.8
-
121
-
-
84858996746
-
Diagnosis and management of maturity onset diabetes of the young (MODY)
-
Thanabalasingham G, Owen KR, (2011) Diagnosis and management of maturity onset diabetes of the young (MODY). BMJ 343: d6044
-
(2011)
BMJ
, vol.343
, pp. d6044
-
-
Thanabalasingham, G.1
Owen, K.R.2
-
122
-
-
0034719412
-
Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo
-
Thisse B, Wright CV, Thisse C, (2000) Activin- and Nodal-related factors control antero-posterior patterning of the zebrafish embryo. Nature 403: 425-428
-
(2000)
Nature
, vol.403
, pp. 425-428
-
-
Thisse, B.1
Wright, C.V.2
Thisse, C.3
-
123
-
-
84870798889
-
Autologous regulatory T cells for the treatment of type 1 diabetes
-
Thompson JA, Perry D, Brusko TM, (2012) Autologous regulatory T cells for the treatment of type 1 diabetes. Curr Diab Rep 12: 623-632
-
(2012)
Curr Diab Rep
, vol.12
, pp. 623-632
-
-
Thompson, J.A.1
Perry, D.2
Brusko, T.M.3
-
124
-
-
77951926420
-
Etiology of type 1 diabetes
-
Todd JA, (2010) Etiology of type 1 diabetes. Immunity 32: 457-467
-
(2010)
Immunity
, vol.32
, pp. 457-467
-
-
Todd, J.A.1
-
125
-
-
84886849781
-
Toward eliminating HLA class i expression to generate universal cells from allogeneic donors
-
Torikai H, Reik A, Soldner F, Warren EH, Yuen C, Zhou Y, Crossland DL, Huls H, Littman N, Zhang Z, Tykodi SS, Kebriaei P, Lee DA, Miller JC, Rebar EJ, Holmes MC, Jaenisch R, Champlin RE, Gregory PD, Cooper LJ, (2013) Toward eliminating HLA class I expression to generate universal cells from allogeneic donors. Blood 122: 1341-1349
-
(2013)
Blood
, vol.122
, pp. 1341-1349
-
-
Torikai, H.1
Reik, A.2
Soldner, F.3
Warren, E.H.4
Yuen, C.5
Zhou, Y.6
Crossland, D.L.7
Huls, H.8
Littman, N.9
Zhang, Z.10
Tykodi, S.S.11
Kebriaei, P.12
Lee, D.A.13
Miller, J.C.14
Rebar, E.J.15
Holmes, M.C.16
Jaenisch, R.17
Champlin, R.E.18
Gregory, P.D.19
Cooper, L.J.20
more..
-
126
-
-
84885101524
-
Toward the development of a global induced pluripotent stem cell library
-
Turner M, Leslie S, Martin NG, Peschanski M, Rao M, Taylor CJ, Trounson A, Turner D, Yamanaka S, Wilmut I, (2013) Toward the development of a global induced pluripotent stem cell library. Cell Stem Cell 13: 382-384
-
(2013)
Cell Stem Cell
, vol.13
, pp. 382-384
-
-
Turner, M.1
Leslie, S.2
Martin, N.G.3
Peschanski, M.4
Rao, M.5
Taylor, C.J.6
Trounson, A.7
Turner, D.8
Yamanaka, S.9
Wilmut, I.10
-
127
-
-
0029810878
-
Recurrence of autoimmune diabetes mellitus in recipients of cadaveric pancreatic grafts
-
Tyden G, Reinholt FP, Sundkvist G, Bolinder J, (1996) Recurrence of autoimmune diabetes mellitus in recipients of cadaveric pancreatic grafts. N Engl J Med 335: 860-863
-
(1996)
N Engl J Med
, vol.335
, pp. 860-863
-
-
Tyden, G.1
Reinholt, F.P.2
Sundkvist, G.3
Bolinder, J.4
-
128
-
-
43549084587
-
Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes
-
Vaxillaire M, Froguel P, (2008) Monogenic diabetes in the young, pharmacogenetics and relevance to multifactorial forms of type 2 diabetes. Endocr Rev 29: 254-264
-
(2008)
Endocr Rev
, vol.29
, pp. 254-264
-
-
Vaxillaire, M.1
Froguel, P.2
-
129
-
-
77951168859
-
Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells
-
Vendrame F, Pileggi A, Laughlin E, Allende G, Martin-Pagola A, Molano RD, Diamantopoulos S, Standifer N, Geubtner K, Falk BA, Ichii H, Takahashi H, Snowhite I, Chen Z, Mendez A, Chen L, Sageshima J, Ruiz P, Ciancio G, Ricordi C, et al, (2010) Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells. Diabetes 59: 947-957
-
(2010)
Diabetes
, vol.59
, pp. 947-957
-
-
Vendrame, F.1
Pileggi, A.2
Laughlin, E.3
Allende, G.4
Martin-Pagola, A.5
Molano, R.D.6
Diamantopoulos, S.7
Standifer, N.8
Geubtner, K.9
Falk, B.A.10
Ichii, H.11
Takahashi, H.12
Snowhite, I.13
Chen, Z.14
Mendez, A.15
Chen, L.16
Sageshima, J.17
Ruiz, P.18
Ciancio, G.19
Ricordi, C.20
more..
-
130
-
-
0026701412
-
Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components
-
Vukicevic S, Kleinman HK, Luyten FP, Roberts AB, Roche NS, Reddi AH, (1992) Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components. Exp Cell Res 202: 1-8
-
(1992)
Exp Cell Res
, vol.202
, pp. 1-8
-
-
Vukicevic, S.1
Kleinman, H.K.2
Luyten, F.P.3
Roberts, A.B.4
Roche, N.S.5
Reddi, A.H.6
-
131
-
-
67649995217
-
Dynamic signaling network for the specification of embryonic pancreas and liver progenitors
-
Wandzioch E, Zaret KS, (2009) Dynamic signaling network for the specification of embryonic pancreas and liver progenitors. Science 324: 1707-1710
-
(2009)
Science
, vol.324
, pp. 1707-1710
-
-
Wandzioch, E.1
Zaret, K.S.2
-
132
-
-
84878591266
-
Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency
-
Wang T, Wu H, Li Y, Szulwach KE, Lin L, Li X, Chen IP, Goldlust IS, Chamberlain SJ, Dodd A, Gong H, Ananiev G, Han JW, Yoon YS, Rudd MK, Yu M, Song CX, He C, Chang Q, Warren ST, Jin P, (2013) Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency. Nat Cell Biol 15: 700-711
-
(2013)
Nat Cell Biol
, vol.15
, pp. 700-711
-
-
Wang, T.1
Wu, H.2
Li, Y.3
Szulwach, K.E.4
Lin, L.5
Li, X.6
Chen, I.P.7
Goldlust, I.S.8
Chamberlain, S.J.9
Dodd, A.10
Gong, H.11
Ananiev, G.12
Han, J.W.13
Yoon, Y.S.14
Rudd, M.K.15
Yu, M.16
Song, C.X.17
He, C.18
Chang, Q.19
Warren, S.T.20
Jin, P.21
more..
-
133
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, Ebina W, Mandal PK, Smith ZD, Meissner A, Daley GQ, Brack AS, Collins JJ, Cowan C, Schlaeger TM, Rossi DJ, (2010) Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 7: 618-630
-
(2010)
Cell Stem Cell
, vol.7
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
Ebina, W.7
Mandal, P.K.8
Smith, Z.D.9
Meissner, A.10
Daley, G.Q.11
Brack, A.S.12
Collins, J.J.13
Cowan, C.14
Schlaeger, T.M.15
Rossi, D.J.16
-
134
-
-
44349157715
-
Multifunctional pancreatic islet encapsulation barriers achieved via multilayer PEG hydrogels
-
Weber LM, Cheung CY, Anseth KS, (2008) Multifunctional pancreatic islet encapsulation barriers achieved via multilayer PEG hydrogels. Cell Transplant 16: 1049-1057
-
(2008)
Cell Transplant
, vol.16
, pp. 1049-1057
-
-
Weber, L.M.1
Cheung, C.Y.2
Anseth, K.S.3
-
135
-
-
84919423709
-
Virtual karyotyping reveals greater chromosomal stability in neural cells derived by transdifferentiation than those from stem cells
-
Weissbein U, Ben-David U, Benvenisty N, (2014) Virtual karyotyping reveals greater chromosomal stability in neural cells derived by transdifferentiation than those from stem cells. Cell Stem Cell 15: 687-691
-
(2014)
Cell Stem Cell
, vol.15
, pp. 687-691
-
-
Weissbein, U.1
Ben-David, U.2
Benvenisty, N.3
-
136
-
-
0035512155
-
Nodal signaling in early vertebrate embryos: Themes and variations
-
Whitman M, (2001) Nodal signaling in early vertebrate embryos: themes and variations. Dev Cell 1: 605-617
-
(2001)
Dev Cell
, vol.1
, pp. 605-617
-
-
Whitman, M.1
-
137
-
-
84903535623
-
Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells
-
Yamada M, Johannesson B, Sagi I, Burnett LC, Kort DH, Prosser RW, Paull D, Nestor MW, Freeby M, Greenberg E, Goland RS, Leibel RL, Solomon SL, Benvenisty N, Sauer MV, Egli D, (2014) Human oocytes reprogram adult somatic nuclei of a type 1 diabetic to diploid pluripotent stem cells. Nature 510: 533-536
-
(2014)
Nature
, vol.510
, pp. 533-536
-
-
Yamada, M.1
Johannesson, B.2
Sagi, I.3
Burnett, L.C.4
Kort, D.H.5
Prosser, R.W.6
Paull, D.7
Nestor, M.W.8
Freeby, M.9
Greenberg, E.10
Goland, R.S.11
Leibel, R.L.12
Solomon, S.L.13
Benvenisty, N.14
Sauer, M.V.15
Egli, D.16
-
138
-
-
0030798108
-
Long-term function of fish islet xenografts in mice by alginate encapsulation
-
Yang H, O'Hali W, Kearns H, Wright JR Jr, (1997) Long-term function of fish islet xenografts in mice by alginate encapsulation. Transplantation 64: 28-32
-
(1997)
Transplantation
, vol.64
, pp. 28-32
-
-
Yang, H.1
O'Hali, W.2
Kearns, H.3
Wright, Jr.J.R.4
-
139
-
-
84881316825
-
Genetically engineered human islets protected from CD8-mediated autoimmune destruction in vivo
-
Zaldumbide A, Alkemade G, Carlotti F, Nikolic T, Abreu JR, Engelse MA, Skowera A, de Koning EJ, Peakman M, Roep BO, Hoeben RC, Wiertz EJ, (2013) Genetically engineered human islets protected from CD8-mediated autoimmune destruction in vivo. Mol Ther 21: 1592-1601
-
(2013)
Mol Ther
, vol.21
, pp. 1592-1601
-
-
Zaldumbide, A.1
Alkemade, G.2
Carlotti, F.3
Nikolic, T.4
Abreu, J.R.5
Engelse, M.A.6
Skowera, A.7
De Koning, E.J.8
Peakman, M.9
Roep, B.O.10
Hoeben, R.C.11
Wiertz, E.J.12
-
140
-
-
53349178722
-
In vivo reprogramming of adult pancreatic exocrine cells to beta-cells
-
Zhou Q, Brown J, Kanarek A, Rajagopal J, Melton DA, (2008) In vivo reprogramming of adult pancreatic exocrine cells to beta-cells. Nature 455: 627-632
-
(2008)
Nature
, vol.455
, pp. 627-632
-
-
Zhou, Q.1
Brown, J.2
Kanarek, A.3
Rajagopal, J.4
Melton, D.A.5
|