Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds

Biomaterials

Volumn 32, Issue 6, 2011, Pages 1536-1542

  Daoud, Jamal T ^a   Petropavlovskaia, Maria S ^b   Patapas, Jason M ^b   Degrandpré, Christian E ^c   DiRaddo, Robert W ^c   Rosenberg, Lawrence ^b   Tabrizian, Maryam ^a,d  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

ECM(extracellular matrix); Islet functionality; Long term culture of human islets; Microfabricated biodegradable scaffold

Indexed keywords

COLLAGEN I; ECM (EXTRACELLULAR MATRIX); EXTRACELLULAR MATRICES; HUMAN ISLETS; IN-VITRO; INSULIN GENE; INSULIN RELEASE; ISLET FUNCTIONALITY; LONG-TERM CULTURE; MICROFABRICATED; PANCREATIC HORMONES; PANCREATIC ISLET; STIMULATION INDICES; SUSPENSION CULTURES; THREE-DIMENSIONAL ENVIRONMENT;

COLLAGEN; GELS; GENE EXPRESSION; INSULIN; MICROFABRICATION; THREE DIMENSIONAL;

SCAFFOLDS;

COLLAGEN TYPE 1; PANCREAS HORMONE;

ARTICLE; BIODEGRADABILITY; CONTROLLED STUDY; EXTRACELLULAR MATRIX; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INSULIN RELEASE; MICROTECHNOLOGY; PANCREAS ISLET; PRIORITY JOURNAL; SUSPENSION CELL CULTURE; THREE DIMENSIONAL IMAGING;

CELLS, CULTURED; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; ISLETS OF LANGERHANS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TISSUE SCAFFOLDS;

EID: 78650302437     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.10.036     Document Type: Article

References (32)

1. Balamurugan A.N., Bottino R., Giannoukakis N., Smetanka C. Prospective and challenges of islet transplantation for the therapy of autoimmune diabetes. Pancreas 2006, 32:231-243.
2. Lai Y., Schneider D., Kidszun A., Hauck-Schmalenberger I., Breier G., Brandhorst D., et al. Vascular endothelial growth factor increases functional beta-cell mass by improvement of angiogenesis of isolated human and murine pancreatic islets. Transplantation 2005, 79:1530-1536.
3. Pileggi A., Molano R.D., Ricordi C., Zahr E., Collins J., Valdes R., et al. Reversal of diabetes by pancreatic islet transplantation into a subcutaneous, neovascularized device. Transplantation 2006, 81:1318-1324.
4. Hamamoto Y., Fujimoto S., Inada A., Takehiro M., Nabe K., Shimono D., et al. Beneficial effect of pretreatment of islets with fibronectin on glucose tolerance after islet transplantation. Horm Metab Res 2003, 35:460-465.
5. Jiang F.X., Naselli G., Harrison L.C. Distinct distribution of laminin and its integrin receptors in the pancreas. J Histochem Cytochem 2002, 50:1625-1632.
6. Kaido T., Yebra M., Cirulli V., Montgomery A.M. Regulation of human beta-cell adhesion, motility, and insulin secretion by collagen IV and its receptor alpha(1)beta(1). J Biol Chem 2004, 279:53762-53769.
7. Thomas F.T., Contreras J.L., Bilbao G., Ricordi C., Curiel D., Thomas J.M. Anoikis, extracellular matrix, and apoptosis factors in isolated cell transplantation. Surgery 1999, 126:299-304.
8. Lucasclerc C., Massart C., Campion J.P., Launois B., Nicol M. Long-term culture of human pancreatic-islets in an extracellular-matrix - morphological and metabolic effects. Mol Cell Endocrinol 1993, 94:9-20.
9. Daoud J., Petropavlovskaia M., Rosenberg L., Tabrizian M. The effect of extracellular matrix components on the preservation of human islet function in vitro. Biomaterials 2010, 31:1676-1682.
10. Landers R., Pfister A., Hubner U., John H., Schmelzeisen R., Mulhaupt R. Fabrication of soft tissue engineering scaffolds by means of rapid prototyping techniques. J Mater Sci 2002, 37:3107-3116.
11. Yang S.F., Leong K.F., Du Z.H., Chua C.K. The design of scaffolds for use in tissue engineering. Part II. Rapid prototyping techniques. Tissue Eng 2002, 8:1-11.
12. Yang S.F., Leong K.F., Du Z.H., Chua C.K. The design of scaffolds for use in tissue engineering. Part 1. Traditional factors. Tissue Eng 2001, 7:679-689.
13. Jansson L., Hellerstrom C. Stimulation by glucose of the blood flow to the pancreatic islets of the rat. Diabetologia 1983, 25:45-50.
14. Blomeier H., Zhang X.M., Rives C., Brissova M., Hughes E., Baker M., et al. Polymer scaffolds as synthetic microenvironments for extrahepatic islet transplantation. Transplantation 2006, 82:452-459.
15. Elcin Y.M., Elcin A.E., Bretzel R.G., Linn T. Pancreatic islet culture and transplantation using chitosan and PLGA scaffolds. Adv Exp Med Biol 2003, 534:255-264.
16. Lutolf M.P., Hubbell J.A. Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nat Biotechnol 2005, 23:47-55.
17. Zavan B., Cortivo R., Tonello C., Abatangelo G. Gland cell cultures into 3D hyaluronan-based scaffolds. J Mater Sci Mater Med 2003, 14:727-729.
18. Salvay D.M., Rives C.B., Zhang X.M., Chen F., Kaufman D.B., Lowe W.L., et al. Extracellular matrix protein-coated scaffolds promote the reversal of diabetes after extrahepatic islet transplantation. Transplantation 2008, 85:1456-1464.
19. Shapiro A.M.J., Lakey J.R.T., Ryan E.A., Korbutt G.S., Toth E., Warnock G.L., et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med 2000, 343:230-238.
20. Yousefi A.M., Gauvin C., Sun L., DiRaddo R.W., Fernandes J. Design and fabrication of 3D-plotted polymeric scaffolds in functional tissue engineering. Polymer Eng Sci 2007, 47:608-618.
21. Vunjak-Novakovic G.F., Radisic M. Cell seeding of polymer scaffolds. Methods Mol Biol 2004, 238:131-146.
22. Xiang B., Muthuswamy S.K. Using three-dimensional acinar structures for molecular and cell biological assays. Meth Enzymol 2006, 406:692-701.
23. Doyle M.E., Egan J.M. Pharmacological agents that directly modulate insulin secretion. Pharmacol Rev 2003, 55:105-131.
24. Chow L.W., Wang L.J., Kaufman D.B., Stupp S.I. Self-assembling nanostructures to deliver angiogenic factors to pancreatic islets. Biomaterials 2010, 31:6154-6161.
25. Lim D.J., Antipenko S., Anderson J., Jaimes K., Stephen B., Bryant S., et al. Enhanced rat islet function and survival in vitro using a biomimetic self-assembled nanomatrix gel. Diabetes 2010, 59. A533.
26. Chun S., Huang Y., Xie W.J., Hou Y., Huang R.P., Song Y.M., et al. Adhesive growth of pancreatic islet cells on a polyglycolic acid fibrous scaffold. Transplant Proc 2008, 40:1658-1663.
27. Kaido T., Yebra M., Cirulli V., Rhodes C., Diaferia G., Montgomery A.M. Impact of defined matrix interactions on insulin production by cultured human beta-cells - effect on insulin content, secretion, and gene transcription. Diabetes 2006, 55:2723-2729.
28. Cabrera O., Berman D.M., Kenyon N.S., Ricordi C., Berggrern P.O., Caicedo A. The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc Natl Acad Sci U S A 2006, 103:2334-2339.
29. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001, 25:402-408.
30. McKinnon C.M., Docherty K. Pancreatic duodenal homeobox-1, PDX-1, a major regulator of beta cell identity and function. Diabetologia 2001, 44:1203-1214.
31. Ashcroft F.M., Gribble F.M. ATP-sensitive K+ channels and insulin secretion: their role in health and disease. Diabetologia 1999, 42:903-919.
32. Henquin J.C. Triggering and amplifying pathways of regulation of insulin secretion by glucose. Diabetes 2000, 49:1751-1760.