De Novo Formation of Insulin-Producing "Neo-β Cell Islets" from Intestinal Crypts

Cell Reports

Volumn 6, Issue 6, 2014, Pages 1046-1058

  Chen, Yi Ju ^a,b   Finkbeiner, Stacy R ^g   Weinblatt, Daniel ^a,b   Emmett, Matthew J ^a   Tameire, Feven ^a   Yousefi, Maryam ^a   Yang, Chenghua ^a,b   Maehr, Rene ^d   Zhou, Qiao ^e   Shemer, Ruth ^f   Dor, Yuval ^f   Li, Changhong ^c   Spence, Jason R ^g   Stanger, Ben Z ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^e Harvard University   (United States)

^f HEBREW UNIVERSITY   (Israel)

^g UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; GLUCOSE; INSULIN; NEUROGENIN 3; STREPTOZOCIN; TAMOXIFEN; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TRANSFORMATION; CELL TYPE; CELL ULTRASTRUCTURE; CRYPT CELL; CYTOPLASM; DIABETES MELLITUS; ENDOCRINE CELL; FEMALE; HUMAN; HUMAN CELL; HYPERGLYCEMIA; IN VIVO STUDY; INSULIN PRODUCING CELL; INTESTINE CRYPT; MALE; MOUSE; NEO BETA CELL ISLET; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; CYTOLOGY; INTESTINE; METABOLISM; PANCREAS ISLET; PHYSIOLOGY; TRANSGENIC MOUSE; EMBRYO; IN VIVO CULTURE; INTESTINE EPITHELIUM CELL;

MUS;

ANIMALS; CELL DIFFERENTIATION; HUMANS; INSULIN; INSULIN-SECRETING CELLS; INTESTINES; ISLETS OF LANGERHANS; MICE; MICE, TRANSGENIC;

EID: 84897030116     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.02.013     Document Type: Article

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