Integrin α3, but not β1, regulates islet cell survival and function via PI3K/Akt signaling pathways

Endocrinology

Volumn 152, Issue 2, 2011, Pages 424-435

  Krishnamurthy, Mansa ^a   Li, Jinming ^a   Fellows, George F ^a   Rosenberg, Lawrence ^b   Goodyer, Cynthia G ^b   Wang, Rennian ^a  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA3 INTEGRIN; BETA1 INTEGRIN; BLOCKING ANTIBODY; CASPASE 3; COLLAGEN TYPE 1; COLLAGEN TYPE 4; FOCAL ADHESION KINASE; GLYCOGEN SYNTHASE KINASE 3BETA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PDX 1;

ALPHA ADRENERGIC RECEPTOR BLOCKING; APOPTOSIS; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; CELL ADHESION; CELL CULTURE; CELL FUNCTION; CELL INTERACTION; CELL PROLIFERATION; CELL SPREADING; CELL SURVIVAL; CONTROLLED STUDY; DIABETES MELLITUS; EXTRACELLULAR MATRIX; FOCAL ADHESION; HUMAN; HUMAN CELL; HUMAN TISSUE; INSULIN RELEASE; MICROENVIRONMENT; PANCREAS ISLET CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

AGED; ANDROSTADIENES; ANIMALS; ANTIBODIES; ANTIGENS, CD29; BLOTTING, WESTERN; BUTADIENES; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; INTEGRIN ALPHA3; ISLETS OF LANGERHANS; MIDDLE AGED; NITRILES; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION;

EID: 79951660073     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2010-0877     Document Type: Article

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