A genome-wide siRNA screen in mammalian cells for regulators of S6 phosphorylation

PLoS ONE

Volumn 10, Issue 3, 2015, Pages

  Papageorgiou, Angela ^a,b   Rapley, Joseph ^a,b   Mesirov, Jill P ^c   Tamayo, Pablo ^c   Avruch, Joseph ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; PROTEIN KINASE; PROTEIN MAP4K3; PROTEIN S6; PROTEIN SERINE THREONINE KINASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; RAC1 PROTEIN; S6 KINASE B1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; MTOR PROTEIN, HUMAN; RNA; S6 KINASE; TARGET OF RAPAMYCIN KINASE;

ANIMAL CELL; ARTICLE; CANCER CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DNA REPAIR; EMBRYO; FEEDBACK SYSTEM; FIBROBLAST; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PROTEIN DEPLETION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; RNA PROCESSING; RNA TRANSLATION; ANIMAL; GENOME; METABOLISM; PHOSPHORYLATION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

EUKARYOTA; MAMMALIA;

ANIMALS; CELL LINE, TUMOR; CELL PROLIFERATION; DNA; DNA REPAIR; GENOME; HUMANS; MICE; PHOSPHORYLATION; PROTEIN BIOSYNTHESIS; RIBOSOMAL PROTEIN S6; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; RNA; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84925882961     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116096     Document Type: Article

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