A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

Human Molecular Genetics

Volumn 11, Issue 5, 2002, Pages 525-534

  Kwiatkowski, David J ^a   Zhang, Hongbing ^a   Bandura, Jennifer L ^a   Heiberger, Kristina M ^a   Glogauer, M ^a   el Hashemite, Nisreen ^a   Onda, Hiroaki ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HAMARTIN; RAPAMYCIN; S6 KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT INHERITANCE; CONTROLLED STUDY; CYSTADENOMA; EMBRYO; EMBRYO DEATH; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SUBSTRATE; FEMALE; FIBROBLAST; GENE MUTATION; GENE TARGETING; HAMARTOMA; HETEROZYGOTE; INCIDENCE; KIDNEY TUMOR; LETHALITY; LIVER DEVELOPMENT; LIVER HEMANGIOMA; MALE; MORTALITY; MOUSE; NONHUMAN; NULL CELL; PREGNANCY; PRIORITY JOURNAL; PROTEIN DEPLETION; SEX DIFFERENCE; TUBEROUS SCLEROSIS; TUMOR GROWTH;

ANIMALIA; MURINAE;

EID: 0036501277     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/11.5.525     Document Type: Article

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