-
2
-
-
0026462778
-
Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor α
-
Korc, M., Chandrasekar, B., Yamanaka, Y., Friess, H., Büchler, M., and Beger, H. G. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor α. J. Clin. Investig., 50: 1352-1360, 1992.
-
(1992)
J. Clin. Investig.
, vol.50
, pp. 1352-1360
-
-
Korc, M.1
Chandrasekar, B.2
Yamanaka, Y.3
Friess, H.4
Büchler, M.5
Beger, H.G.6
-
4
-
-
0029103330
-
Control of p70 s6 kinase by kinase activity of FRAP in vivo
-
Brown, E. J., Beal, P. A., Keith, C. T., Chen, J., Shin, T. B., and Schreber, S. L. Control of p70 s6 kinase by kinase activity of FRAP in vivo. Nature (Lond.), 377: 441-446, 1995.
-
(1995)
Nature (Lond.)
, vol.377
, pp. 441-446
-
-
Brown, E.J.1
Beal, P.A.2
Keith, C.T.3
Chen, J.4
Shin, T.B.5
Schreber, S.L.6
-
5
-
-
0026759874
-
Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase
-
Washington DC
-
Price, D. J., Grove, J. R., Calvo, V., Avruch, J., and Bierer, B. E. Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase. Science (Washington DC), 257: 973-977, 1992.
-
(1992)
Science
, vol.257
, pp. 973-977
-
-
Price, D.J.1
Grove, J.R.2
Calvo, V.3
Avruch, J.4
Bierer, B.E.5
-
7
-
-
0028788935
-
The 70 kDa S6 kinase: Regulation of a kinase with multiple roles in mitogenic signalling
-
Chou, M. M., and Blenis, J. The 70 kDa S6 kinase: regulation of a kinase with multiple roles in mitogenic signalling. Curr. Opin. Cell Biol., 7: 806-814, 1995.
-
(1995)
Curr. Opin. Cell Biol.
, vol.7
, pp. 806-814
-
-
Chou, M.M.1
Blenis, J.2
-
8
-
-
0026598063
-
Effects of rapamycin on cultured hepatocyte proliferation and gene expression
-
Francavilla, A., Carr, B. I., Starzl, T. E., Azzarone, A., Carrieri, G., and Zeng, Q. H. Effects of rapamycin on cultured hepatocyte proliferation and gene expression. Hepatology, 15: 871-877, 1992.
-
(1992)
Hepatology
, vol.15
, pp. 871-877
-
-
Francavilla, A.1
Carr, B.I.2
Starzl, T.E.3
Azzarone, A.4
Carrieri, G.5
Zeng, Q.H.6
-
9
-
-
0028876806
-
Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells
-
Marx, S. O., Jayaraman, T., Go, L. O., and Marks, A. R. Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells. Circ. Res., 76: 412-417, 1995.
-
(1995)
Circ. Res.
, vol.76
, pp. 412-417
-
-
Marx, S.O.1
Jayaraman, T.2
Go, L.O.3
Marks, A.R.4
-
10
-
-
0029794614
-
s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells
-
s6k phosphorylation, cell proliferation, and colony formation in small cell lung cancer cells. Cancer Res., 56: 3895-3897, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 3895-3897
-
-
Seufferlein, T.1
Rozengurt, E.2
-
11
-
-
0030915898
-
S6k
-
S6k. EMBO J., 16: 3693-3704, 1997.
-
(1997)
EMBO J.
, vol.16
, pp. 3693-3704
-
-
Jefferies, H.B.1
Fumagalli, S.2
Dennis, P.B.3
Reinhard, C.4
Pearson, R.B.5
Thomas, G.6
-
12
-
-
0032054816
-
The mRNA 5′cap-binding protein eIF4E and control of cell growth
-
Sonenberg, N., and Gingras, A. C. The mRNA 5′cap-binding protein eIF4E and control of cell growth. Curr. Opin. Cell Biol., 10: 268-275, 1998.
-
(1998)
Curr. Opin. Cell Biol.
, vol.10
, pp. 268-275
-
-
Sonenberg, N.1
Gingras, A.C.2
-
13
-
-
0030443685
-
The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth
-
Rousseau, D., Gingras, A. C., Pause, A., and Sonenberg, N. The eIF4E-binding proteins 1 and 2 are negative regulators of cell growth. Oncogene, 13: 2415-2420, 1996.
-
(1996)
Oncogene
, vol.13
, pp. 2415-2420
-
-
Rousseau, D.1
Gingras, A.C.2
Pause, A.3
Sonenberg, N.4
-
14
-
-
0030716488
-
Regulation of eIF-4EBP1 phosphorylation by mTOR
-
Hara, K., Yonezawa, K., Kozlowski, M. T., Sugimoto, T., Andrabi, K., Weng, Q. P., Kasuga, M., Nishimoto, I., and Avruch, J. Regulation of eIF-4EBP1 phosphorylation by mTOR. J. Biol. Chem., 272: 26457-26463, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26457-26463
-
-
Hara, K.1
Yonezawa, K.2
Kozlowski, M.T.3
Sugimoto, T.4
Andrabi, K.5
Weng, Q.P.6
Kasuga, M.7
Nishimoto, I.8
Avruch, J.9
-
15
-
-
0032574823
-
Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity
-
Kawasome, H., Papst, P., Webb, S., Keller, G. M., Johnson, G. L., Gelfand, E. W., and Terada, N. Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity. Proc. Natl. Acad. Sci. USA, 95: 5033-5038, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 5033-5038
-
-
Kawasome, H.1
Papst, P.2
Webb, S.3
Keller, G.M.4
Johnson, G.L.5
Gelfand, E.W.6
Terada, N.7
-
16
-
-
0029890687
-
Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus
-
Gingras, A-C., Svitkin, Y., Belsham, G., Pause, A., and Sonenberg, N. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. Proc. Natl. Acad. Sci. USA, 93: 5578-5583, 1996.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5578-5583
-
-
Gingras, A.-C.1
Svitkin, Y.2
Belsham, G.3
Pause, A.4
Sonenberg, N.5
-
17
-
-
0029095931
-
Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway
-
Lin, T. A., Kong, X. M., Saltiel, A. R., Blackshear, P. J., and Lawrence, J. C. Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway. J. Biol. Chem., 270: 18531-18538, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 18531-18538
-
-
Lin, T.A.1
Kong, X.M.2
Saltiel, A.R.3
Blackshear, P.J.4
Lawrence, J.C.5
-
18
-
-
0033557578
-
Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells
-
Hosoi, H., Dilling, M. B., Shikata, T., Liu, L. N., Shu, L., Ashmun, R. A., Germain, G. S., Abraham, R. T., and Houghton, P. J. Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells. Cancer Res., 59: 886-894, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 886-894
-
-
Hosoi, H.1
Dilling, M.B.2
Shikata, T.3
Liu, L.N.4
Shu, L.5
Ashmun, R.A.6
Germain, G.S.7
Abraham, R.T.8
Houghton, P.J.9
-
19
-
-
0018876637
-
Positive correlation between histological tumor involvement and generation of tumor cell colonies in agarose in specimens taken directly from patients with small cell carcinoma of the lung
-
Carney, D. N., Gazdar, A. F., and Minna, J. D. Positive correlation between histological tumor involvement and generation of tumor cell colonies in agarose in specimens taken directly from patients with small cell carcinoma of the lung. Cancer Res., 40: 1820-1823, 1980.
-
(1980)
Cancer Res.
, vol.40
, pp. 1820-1823
-
-
Carney, D.N.1
Gazdar, A.F.2
Minna, J.D.3
-
21
-
-
0028172867
-
Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin
-
Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin. Nature (Lond.), 372: 570-573, 1994.
-
(1994)
Nature (Lond.)
, vol.372
, pp. 570-573
-
-
Nourse, J.1
Firpo, E.2
Flanagan, W.M.3
Coats, S.4
Polyak, K.5
Lee, M.H.6
Massague, J.7
Crabtree, G.R.8
Roberts, J.M.9
-
22
-
-
0031032824
-
S6k activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells
-
S6k activation from DNA synthesis stimulated by bombesin and insulin in Swiss 3T3 cells. J. Biol. Chem., 272: 2509-2514, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 2509-2514
-
-
Withers, D.J.1
Seufferlein, T.2
Mann, D.3
Garcia, B.4
Jones, N.5
Rozengurt, E.6
-
23
-
-
0032538890
-
Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional kinase
-
Shima, H., Pende, M., Chen, Y., Fumagalli, S., Thomas, G., and Kozma, S. C. Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional kinase. EMBO J., 17: 6649-6659, 1998.
-
(1998)
EMBO J.
, vol.17
, pp. 6649-6659
-
-
Shima, H.1
Pende, M.2
Chen, Y.3
Fumagalli, S.4
Thomas, G.5
Kozma, S.C.6
-
24
-
-
0032911889
-
S6k-independent signaling in growth factor-stimulated NIH 3T3 cells
-
S6k-independent signaling in growth factor-stimulated NIH 3T3 cells. Mol. Cell. Biol., 19: 1569-1581, 1999.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 1569-1581
-
-
Takuwa, N.1
Fukui, Y.2
Takuwa, Y.3
-
25
-
-
0032485937
-
1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability
-
1 to S transition is mediated by effects on cyclin D1 mRNA and protein stability. J. Biol, Chem., 273: 14424-14429, 1998.
-
(1998)
J. Biol, Chem.
, vol.273
, pp. 14424-14429
-
-
Hashemolhosseini, S.1
Nagamine, Y.2
Morley, S.J.3
Desrivieres, S.4
Mercep, L.5
Ferrari, S.6
-
26
-
-
0027938209
-
Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age
-
Hunter, T., and Pines, J. Cyclins and cancer. II. Cyclin D and CDK inhibitors come of age. Cell, 79: 573-582, 1994.
-
(1994)
Cell
, vol.79
, pp. 573-582
-
-
Hunter, T.1
Pines, J.2
-
27
-
-
0030337951
-
Relevance of cyclin D1 and other molecular markers to cancer chemoprevention
-
Weinstein, I. B. Relevance of cyclin D1 and other molecular markers to cancer chemoprevention. J. Cell. Biochem., 25: 23-28, 1996.
-
(1996)
J. Cell. Biochem.
, vol.25
, pp. 23-28
-
-
Weinstein, I.B.1
-
28
-
-
0030969478
-
Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis
-
Gansauge, S., Gansauge, F., Ramadani, M., Stoibbe, H., Rau, B., Harada, N., and Beger, H. G. Overexpression of cyclin D1 in human pancreatic carcinoma is associated with poor prognosis. Cancer Res., 57: 1634-1637, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 1634-1637
-
-
Gansauge, S.1
Gansauge, F.2
Ramadani, M.3
Stoibbe, H.4
Rau, B.5
Harada, N.6
Beger, H.G.7
-
29
-
-
0032518616
-
Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum
-
Kornmann, M., Arber, N., and Korc, M. Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum. J. Clin. Investig., 101: 344-352, 1998.
-
(1998)
J. Clin. Investig.
, vol.101
, pp. 344-352
-
-
Kornmann, M.1
Arber, N.2
Korc, M.3
|