Flavonoid intake and cardiovascular disease risk

Current Opinion in Food Science

Volumn 2, Issue , 2015, Pages 92-99

  Feliciano, Rodrigo P ^a   Pritzel, Sarah ^a   Heiss, Christian ^a   Rodriguez Mateos, Ana ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84924407506     PISSN: 22147993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cofs.2015.02.006     Document Type: Review

References (64)

1. Boeing H., Bechthold A., Bub A., Ellinger S., Haller D., Kroke A., Leschik-Bonnet E., Muller M.J., Oberritter H., Schulze M., et al. Critical review: vegetables and fruit in the prevention of chronic diseases. Eur J Nutr 2012, 51:637-663.
2. van Dam R.M., Naidoo N., Landberg R. Dietary flavonoids and the development of type 2 diabetes and cardiovascular diseases: review of recent findings. Curr Opin Lipidol 2013, 24:25-33.
3. Aron P.M., Kennedy J.A. Flavan-3-ols: nature, occurrence and biological activity. Mol Nutr Food Res 2008, 52:79-104.
4. USDA USDA Database for the Flavonoid Content of Selected Foods, Release 3.1 (December 2013) 2013.
5. Feliciano R.P., Shea M.P., Shanmuganayagam D., Krueger C.G., Howell A.B., Reed J.D. Comparison of isolated cranberry (Vaccinium macrocarpon Ait.) proanthocyanidins to catechin and procyanidins A2 and B2 for use as standards in the 4-(dimethylamino)cinnamaldehyde assay. J Agric Food Chem 2012, 60:4578-4585.
6. Ottaviani J.I., Momma T.Y., Kuhnle G.K., Keen C.L., Schroeter H. Structurally related (-)-epicatechin metabolites in humans: assessment using de novo chemically synthesized authentic standards. Free Radic Biol Med 2012, 52:1403-1412.
7. Czank C., Cassidy A., Zhang Q., Morrison D.J., Preston T., Kroon P.A., Botting N.P., Kay C.D. Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a (13)C-tracer study. Am J Clin Nutr 2013, 97:995-1003.
8. Del Rio D., Rodriguez-Mateos A., Spencer J.P., Tognolini M., Borges G., Crozier A. Dietary (poly)phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases. Antioxid Redox Signal 2013, 18:1818-1892.
9. Rodriguez-Mateos A., Vauzour D., Krueger C.G., Shanmuganayagam D., Reed J., Calani L., Mena P., Del Rio D., Crozier A. Bioavailability, bioactivity and impact on health of dietary flavonoids and related compounds: an update. Arch Toxicol 2014, 88:1803-1853.
10. Hollman P.C.H. Unravelling of the health effects of polyphenols is a complex puzzle complicated by metabolism. Arch Biochem Biophys 2014, 559:100-105.
11. Chiou Y.-S., Wu J.-C., Huang Q., Shahidi F., Wang Y.-J., Ho C.-T., Pan M.-H. Metabolic and colonic microbiota transformation may enhance the bioactivities of dietary polyphenols. J Funct Foods 2014, 7:3-25.
12. Peterson J.J., Dwyer J.T., Jacques P.F., McCullough M.L. Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations. Nutr Rev 2012, 70:491-508.
13. Zamora-Ros R., Touillaud M., Rothwell J.A., Romieu I., Scalbert A. Measuring exposure to the polyphenol metabolome in observational epidemiologic studies: current tools and applications and their limits. Am J Clin Nutr 2014, 100:11-26.
14. Pimpao R.C., Dew T., Figueira M.E., McDougall G.J., Stewart D., Ferreira R.B., Santos C.N., Williamson G. Urinary metabolite profiling identifies novel colonic metabolites and conjugates of phenolics in healthy volunteers. Mol Nutr Food Res 2014, 58:1414-1425.
15. Pujos-Guillot E., Hubert J., Martin J.F., Lyan B., Quintana M., Claude S., Chabanas B., Rothwell J.A., Bennetau-Pelissero C., Scalbert A., et al. Mass spectrometry-based metabolomics for the discovery of biomarkers of fruit and vegetable intake: citrus fruit as a case study. J Proteome Res 2013, 12:1645-1659.
16. Lehtonen H.-M., Lindstedt A., Jarvinen R., Sinkkonen J., Graca G., Viitanen M., Kallio H., Gil A.M. H-1 NMR-based metabolic fingerprinting of urine metabolites after consumption of lingonberries (Vaccinium vitis-idaea) with a high-fat meal. Food Chem 2013, 138:982-990.
17. Catalan U., Rodriguez M.A., Ras M.R., Macia A., Mallol R., Vinaixa M., Fernandez-Castillejo S., Valls R.M., Pedret A., Griffin J.L., et al. Biomarkers of food intake and metabolite differences between plasma and red blood cell matrices; a human metabolomic profile approach. Mol Biosyst 2013, 9:1411-1422.
18. Wilson L., Arabshahi A., Simons B., Prasain J.K., Barnes S. Improved high sensitivity analysis of polyphenols and their metabolites by nano-liquid chromatography-mass spectrometry. Arch Biochem Biophys 2014, 559:3-11.
19. Neveu V., Perez-Jimenez J., Vos F., Crespy V., du Chaffaut L., Mennen L., Knox C., Eisner R., Cruz J., Wishart D., et al. Phenol-Explorer: an online comprehensive database on polyphenol contents in foods. Database (Oxford) 2010, 2010:bap024.
20. Scalbert A., Brennan L., Manach C., Andres-Lacueva C., Dragsted L.O., Draper J., Rappaport S.M., van der Hooft J.J., Wishart D.S. The food metabolome: a window over dietary exposure. Am J Clin Nutr 2014, 99:1286-1308.
21. Medina S., Dominguez-Perles R., Ferreres F., Tomas-Barberan F.A., Gil-Izquierdo A. The effects of the intake of plant foods on the human metabolome. Trac - Trends Anal Chem 2013, 52:88-99.
22. Rothwell J.A., Perez-Jimenez J., Neveu V., Medina-Remon A., M'Hiri N., Garcia-Lobato P., Manach C., Knox C., Eisner R., Wishart D.S., et al. Phenol-Explorer 3.0: a major update of the Phenol-Explorer database to incorporate data on the effects of food processing on polyphenol content. Database (Oxford) 2013, 2013:bat070.
23. Cassidy A., Mukamal K.J., Liu L., Franz M., Eliassen A.H., Rimm E.B. High anthocyanin intake is associated with a reduced risk of myocardial infarction in young and middle-aged women. Circulation 2013, 127:188-196.
24. Zamora-Ros R., Jimenez C., Cleries R., Agudo A., Sanchez M.J., Sanchez-Cantalejo E., Molina-Montes E., Navarro C., Chirlaque M.D., Maria Huerta J., et al. Dietary flavonoid and lignan intake and mortality in a Spanish cohort. Epidemiology 2013, 24:726-733.
25. Ivey K.L., Lewis J.R., Prince R.L., Hodgson J.M. Tea and non-tea flavonol intakes in relation to atherosclerotic vascular disease mortality in older women. Br J Nutr 2013, 110:1648-1655.
26. Tresserra-Rimbau A., Rimm E.B., Medina-Remon A., Martinez-Gonzalez M.A., de la Torre R., Corella D., Salas-Salvado J., Gomez-Gracia E., Lapetra J., Aros F., et al. Inverse association between habitual polyphenol intake and incidence of cardiovascular events in the PREDIMED study. Nutr Metab Cardiovasc Dis 2014, 24:639-647.
27. Wang X., Ouyang Y.Y., Liu J., Zhao G. Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies. Brit J Nutr 2014, 111:1-11.
28. Jiang W., Wei H., He B. Dietary flavonoids intake and the risk of coronary heart disease: a dose-response meta-analysis of 15 prospective studies. Thromb Res 2015, 135:459-463.
29. Hooper L., Kay C., Abdelhamid A., Kroon P.A., Cohn J.S., Rimm E.B., Cassidy A. Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials. Am J Clin Nutr 2012, 95:740-751.
30. Ried K., Sullivan T.R., Fakler P., Frank O.R., Stocks N.P. Effect of cocoa on blood pressure. Cochrane Database Syst Rev 2012, 8:CD008893.
31. Curtis P.J., Potter J., Kroon P.A., Wilson P., Dhatariya K., Sampson M., Cassidy A. Vascular function and atherosclerosis progression after 1 y of flavonoid intake in statin-treated postmenopausal women with type 2 diabetes: a double-blind randomized controlled trial. Am J Clin Nutr 2013, 97:936-942.
32. West S.G., McIntyre M.D., Piotrowski M.J., Poupin N., Miller D.L., Preston A.G., Wagner P., Groves L.F., Skulas-Ray A.C. Effects of dark chocolate and cocoa consumption on endothelial function and arterial stiffness in overweight adults. Br J Nutr 2014, 111:653-661.
33. Rodriguez-Mateos A., Rendeiro C., Bergillos-Meca T., Tabatabaee S., George T., Heiss C., Spencer J.P. Intake and time dependence of blueberry flavonoid-induced improvements in vascular function: a randomized, controlled, double-blind, crossover intervention study with mechanistic insights into biological activity. Am J Clin Nutr 2013, 98:1179-1191.
34. Rodriguez-Mateos A., Pino-Garcia R.D., George T.W., Vidal-Diez A., Heiss C., Spencer J.P.E. Impact of processing on the bioavailability and vascular effects of blueberry (poly)phenols. Mol Nutr Food Res 2014, 58:1952-1961.
35. Basu A., Betts N.M., Nguyen A., Newman E.D., Fu D., Lyons T.J. Freeze-dried strawberries lower serum cholesterol and lipid peroxidation in adults with abdominal adiposity and elevated serum lipids. J Nutr 2014, 144:830-837.
36. Shema Didi L., Kristal B., Sela S., Geron R., Ore L. Does pomegranate intake attenuate cardiovascular risk factors in hemodialysis patients?. Nutr J 2014, 13:18.
37. Siasos G., Tousoulis D., Kokkou E., Oikonomou E., Kollia M.E., Verveniotis A., Gouliopoulos N., Zisimos K., Plastiras A., Maniatis K., et al. Favorable effects of concord grape juice on endothelial function and arterial stiffness in healthy smokers. Am J Hypertens 2014, 27:38-45.
38. Mogollon J.A., Bujold E., Lemieux S., Bourdages M., Blanchet C., Bazinet L., Couillard C., Noel M., Dodin S. Blood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trial. Nutr J 2013, 12:41.
39. Neufingerl N., Zebregs Y.E., Schuring E.A., Trautwein E.A. Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial. Am J Clin Nutr 2013, 97:1201-1209.
40. Del Bo C., Riso P., Campolo J., Moller P., Loft S., Klimis-Zacas D., Brambilla A., Rizzolo A., Porrini M. A single portion of blueberry (Vaccinium corymbosum L.) improves protection against DNA damage but not vascular function in healthy male volunteers. Nutr Res 2013, 33:220-227.
41. Riso P., Klimis-Zacas D., Del Bo C., Martini D., Campolo J., Vendrame S., Moller P., Loft S., De Maria R., Porrini M. Effect of a wild blueberry (Vaccinium angustifolium) drink intervention on markers of oxidative stress, inflammation and endothelial function in humans with cardiovascular risk factors. Eur J Nutr 2013, 52:949-961.
42. Ruel G., Lapointe A., Pomerleau S., Couture P., Lemieux S., Lamarche B., Couillard C. Evidence that cranberry juice may improve augmentation index in overweight men. Nutr Res 2013, 33:41-49.
43. Flammer A.J., Martin E.A., Gossl M., Widmer R.J., Lennon R.J., Sexton J.A., Loeffler D., Khosla S., Lerman L.O., Lerman A. Polyphenol-rich cranberry juice has a neutral effect on endothelial function but decreases the fraction of osteocalcin-expressing endothelial progenitor cells. Eur J Nutr 2013, 52:289-296.
44. Bohn S.K., Croft K.D., Burrows S., Puddey I.B., Mulder T.P., Fuchs D., Woodman R.J., Hodgson J.M. Effects of black tea on body composition and metabolic outcomes related to cardiovascular disease risk: a randomized controlled trial. Food Funct 2014, 5:1613-1620.
45. Chen G., Wang H., Zhang X., Yang S.T. Nutraceuticals and functional foods in the management of hyperlipidemia. Crit Rev Food Sci Nutr 2014, 54:1180-1201.
46. Feliciano R.P., Meudt J.J., Shanmuganayagam D., Krueger C.G., Reed J.D. Ratio of 'A-type' to 'B-type' proanthocyanidin interflavan bonds affects extra-intestinal pathogenic Escherichia coli invasion of gut epithelial cells. J Agric Food Chem 2014, 62:3919-3925.
47. de Bock M., Derraik J.G., Brennan C.M., Biggs J.B., Morgan P.E., Hodgkinson S.C., Hofman P.L., Cutfield W.S. Olive (Olea europaea L.) leaf polyphenols improve insulin sensitivity in middle-aged overweight men: a randomized, placebo-controlled, crossover trial. PLoS ONE 2013, 8:e57622.
48. Liu Z.-m., Ho S.C., Chen Y.-m., Ho S., To K., Tomlinson B., Woo J. Whole soy, but not purified daidzein, had a favorable effect on improvement of cardiovascular risks: a 6-month randomized, double-blind, and placebo-controlled trial in equol-producing postmenopausal women. Mol Nutr Food Res 2014, 58:709-717.
49. Liu Z.M., Ho S.C., Chen Y.M., Woo J. Effect of soy protein and isoflavones on blood pressure and endothelial cytokines: a 6-month randomized controlled trial among postmenopausal women. J Hypertens 2013, 31:384-392.
50. Kim J., Lee H., Lee O., Lee K.H., Lee Y.B., Young K.D., Jeong Y.H., Choue R. Isoflavone supplementation influenced levels of triglyceride and luteunizing hormone in Korean postmenopausal women. Arch Pharm Res 2013, 36:306-313.
51. Mainini G., Torella M., Di Donna M.C., Esposito E., Ercolano S., Correa R., Cucinella G., Stradella L., Luisi A., Basso A., et al. Nonhormonal management of postmenopausal women: effects of a red clover based isoflavones supplementation on climacteric syndrome and cardiovascular risk serum profile. Clin Exp Obstet Gynecol 2013, 40:337-341.
52. Hassellund S.S., Flaa A., Kjeldsen S.E., Seljeflot I., Karlsen A., Erlund I., Rostrup M. Effects of anthocyanins on cardiovascular risk factors and inflammation in pre-hypertensive men: a double-blind randomized placebo-controlled crossover study. J Hum Hypertens 2013, 27:100-106.
53. Zhu Y., Ling W., Guo H., Song F., Ye Q., Zou T., Li D., Zhang Y., Li G., Xiao Y., et al. Anti-inflammatory effect of purified dietary anthocyanin in adults with hypercholesterolemia: a randomized controlled trial. Nutr Metab Cardiovasc Dis 2013, 23:843-849.
54. Wright O.R., Netzel G.A., Sakzewski A.R. A randomized, double-blind, placebo-controlled trial of the effect of dried purple carrot on body mass, lipids, blood pressure, body composition, and inflammatory markers in overweight and obese adults: the QUENCH trial. Can J Physiol Pharmacol 2013, 91:480-488.
55. Tome-Carneiro J., Larrosa M., Yanez-Gascon Ma.J., Davalos A., Gil-Zamorano J., Gonzalvez M., Garcia-Almagro F.J., Ruiz Ros J., Tomas-Barberan F.A., Espin J.C., et al. One-year supplementation with a grape extract containing resveratrol modulates inflammatory-related microRNAs and cytokines expression in peripheral blood mononuclear cells of type 2 diabetes and hypertensive patients with coronary artery disease. Pharmacol Res 2013, 72:69-82.
56. Yubero N., Sanz-Buenhombre M., Guadarrama A., Villanueva S., Carrion J.M., Larrarte E., Moro C. LDL cholesterol-lowering effects of grape extract used as a dietary supplement on healthy volunteers. Int J Food Sci Nutr 2013, 64:400-406.
57. Ras R.T., Zock P.L., Zebregs Y.E., Johnston N.R., Webb D.J., Draijer R. Effect of polyphenol-rich grape seed extract on ambulatory blood pressure in subjects with pre- and stage I hypertension. Br J Nutr 2013, 110:2234-2241.
58. Terauchi M., Horiguchi N., Kajiyama A., Akiyoshi M., Owa Y., Kato K., Kubota T. Effects of grape seed proanthocyanidin extract on menopausal symptoms, body composition, and cardiovascular parameters in middle-aged women: a randomized, double-blind, placebo-controlled pilot study. Menopause 2014, 21:990-996.
59. Pfeuffer M., Auinger A., Bley U., Kraus-Stojanowic I., Laue C., Winkler P., Rüfer C.E., Frank J., Bösch-Saadatmandi C., Rimbach G., et al. Effect of quercetin on traits of the metabolic syndrome, endothelial function and inflammation in men with different APOE isoforms. Nutr Metab Cardiovasc Dis 2013, 23:403-409.
60. Zahedi M., Ghiasvand R., Feizi A., Asgari G., Darvish L. Does quercetin improve cardiovascular risk factors and inflammatory biomarkers in women with type 2 diabetes: a double-blind randomized controlled clinical trial. Int J Prev Med 2013, 4:777-785.
61. Perez A., Gonzalez-Manzano S., Jimenez R., Perez-Abud R., Haro J.M., Osuna A., Santos-Buelga C., Duarte J., Perez-Vizcaino F. The flavonoid quercetin induces acute vasodilator effects in healthy volunteers: correlation with beta-glucuronidase activity. Pharmacol Res 2014, 89:11-18.
62. Squadrito F., Marini H., Bitto A., Altavilla D., Polito F., Adamo E.B., D'Anna R., Arcoraci V., Burnett B.P., Minutoli L., et al. Genistein in the metabolic syndrome: results of a randomized clinical trial. J Clin Endocrinol Metab 2013, 98:3366-3374.
63. Irace C., Marini H., Bitto A., Altavilla D., Polito F., Adamo E.B., Arcoraci V., Minutoli L., Di Benedetto A., Di Vieste G., et al. Genistein and endothelial function in postmenopausal women with metabolic syndrome. Eur J Clin Invest 2013, 43:1025-1031.
64. Egert S., Rimbach G. Which sources of flavonoids: complex diets or dietary supplements?. Adv Nutr 2011, 2:8-14.