Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable

International Journal of Hematology

Volumn 101, Issue 3, 2015, Pages 229-242

  Zoi, Katerina ^a   Cross, Nicholas C P ^b,c  

^a BIOMEDICAL RESEARCH FOUNDATION   (Greece)

^b SALISBURY DISTRICT HOSPITAL   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Atypical CML; CMML; CNL; DNA damage response; Epigenetic regulation; MDS MPN U; RNA splicing; Signalling pathways; Transcription factors

Indexed keywords

ASXL1 PROTEIN; CBL PROTEIN; CD135 ANTIGEN; CEBPA PROTEIN; COHESIN; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; JANUS KINASE 2; KIT PROTEIN; NF1 PROTEIN; NOTCH RECEPTOR; NUCLEOPHOSMIN; PROTEIN; PROTEIN P53; PROTEIN TYROSINE PHOSPHATASE SHP 2; RAS PROTEIN; SETBP1 PROTEIN; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

ATYPICAL CHRONIC MYELOID LEUKEMIA; CANCER PROGNOSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC MYELOMONOCYTIC LEUKEMIA; COMPARATIVE GENOMIC HYBRIDIZATION; DNA DAMAGE; DNA METHYLATION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE MUTATION; HISTONE MODIFICATION; HUMAN; MOLECULAR PATHOLOGY; MYELODYSPLASTIC SYNDROME; MYELOPROLIFERATIVE NEOPLASM; PHENOTYPE; REVIEW; RNA SPLICING; RNA TRANSCRIPTION; SINGLE NUCLEOTIDE POLYMORPHISM; UPREGULATION; ANIMAL; CHROMOSOME ANALYSIS; CLASSIFICATION; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; METABOLISM; MIXED MYELODYSPLASTIC MYELOPROLIFERATIVE DISEASE; MUTATION; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CYTOGENETIC ANALYSIS; DNA DAMAGE; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA, MYELOID, CHRONIC, ATYPICAL, BCR-ABL NEGATIVE; LEUKEMIA, MYELOMONOCYTIC, CHRONIC; MUTATION; MYELODYSPLASTIC-MYELOPROLIFERATIVE DISEASES; RNA SPLICING; SIGNAL TRANSDUCTION;

EID: 84924150453     PISSN: 09255710     EISSN: 18653774     Source Type: Journal    
DOI: 10.1007/s12185-014-1670-3     Document Type: Review

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