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Volumn 101, Issue 2, 2003, Pages 673-680

Implications of somatic mutations in the AML1 gene in radiation-associated and therapy-related myelodysplastic syndrome/acute myeloid leukemia

Author keywords

[No Author keywords available]

Indexed keywords

ALKYLATING AGENT; CYCLOPHOSPHAMIDE; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; METHOTREXATE; MITOXANTRONE; NIMUSTINE; PREDNISOLONE; RANIMUSTINE; VINCRISTINE SULFATE;

EID: 0037438508     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2002-04-1010     Document Type: Article
Times cited : (145)

References (37)
  • 1
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell. 1996;84:321-330.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 2
    • 0029918597 scopus 로고    scopus 로고
    • Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis
    • Wang Q, Stacy T, Binder M, Marin-Padilla M, Sharpe AH, Speck NA. Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis. Proc Natl Acad Sci USA. 1996;93:3444-3449.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3444-3449
    • Wang, Q.1    Stacy, T.2    Binder, M.3    Marin-Padilla, M.4    Sharpe, A.H.5    Speck, N.A.6
  • 3
    • 0029973591 scopus 로고    scopus 로고
    • Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor β
    • Sasaki K, Yagi H, Bronson RT, et al. Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor β. Proc Natl Acad Sci U S A. 1996;93:12359-12363.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 12359-12363
    • Sasaki, K.1    Yagi, H.2    Bronson, R.T.3
  • 4
    • 0030588487 scopus 로고    scopus 로고
    • The CBFβ subunit is essential for CBFα2 (AML1) function in vivo
    • Wang Q, Stacy T, Miller JD, et al. The CBFβ subunit is essential for CBFα2 (AML1) function in vivo. Cell. 1996;87:697-708.
    • (1996) Cell , vol.87 , pp. 697-708
    • Wang, Q.1    Stacy, T.2    Miller, J.D.3
  • 5
    • 0030915268 scopus 로고    scopus 로고
    • Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor
    • Niki M, Okada H, Takano H, et al. Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor. Proc Natl Acad Sci U S A. 1997;94:5697-5702.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 5697-5702
    • Niki, M.1    Okada, H.2    Takano, H.3
  • 6
    • 0032822953 scopus 로고    scopus 로고
    • The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: Biology and clinical significance
    • Downing JR. The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance. Br J Haematol. 1999;106:296-308.
    • (1999) Br J Haematol , vol.106 , pp. 296-308
    • Downing, J.R.1
  • 7
    • 0028925282 scopus 로고
    • The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation
    • Meyers S, Lenny N, Hiebert SW. The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation. Mol Cell Biol. 1995;15:1974-1982.
    • (1995) Mol Cell Biol , vol.15 , pp. 1974-1982
    • Meyers, S.1    Lenny, N.2    Hiebert, S.W.3
  • 8
    • 0033559746 scopus 로고    scopus 로고
    • Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2αB gene associated with myeloblastic leukemias
    • Osato M,Asou N,Abdalla E, et al. Biallelic and heterozygous point mutations in the runt domain of the AML1/PEBP2αB gene associated with myeloblastic leukemias. Blood. 1999;93:1817-1824.
    • (1999) Blood , vol.93 , pp. 1817-1824
    • Osato, M.1    Asou, N.2    Abdalla, E.3
  • 9
    • 0034332068 scopus 로고    scopus 로고
    • Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis
    • Imai Y, Kurokawa M, Izutsu K, et al. Mutations of the AML1 gene in myelodysplastic syndrome and their functional implications in leukemogenesis. Blood. 2000;96:3154-3160.
    • (2000) Blood , vol.96 , pp. 3154-3160
    • Imai, Y.1    Kurokawa, M.2    Izutsu, K.3
  • 10
    • 0034667690 scopus 로고    scopus 로고
    • High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2αB gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21
    • Preudhomme C,Warot-Loze D, Roumier C, et al. High incidence of biallelic point mutations in the Runt domain of the AML1/PEBP2αB gene in Mo acute myeloid leukemia and in myeloid malignancies with acquired trisomy 21. Blood. 2000;96:2862-2869.
    • (2000) Blood , vol.96 , pp. 2862-2869
    • Preudhomme, C.1    Warot-Loze, D.2    Roumier, C.3
  • 11
    • 0032830638 scopus 로고    scopus 로고
    • Haplo-insufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
    • Song W-J, Sullivan MG, Legare RD, et al. Haplo-insufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nature Genet. 1999;23:166-175.
    • (1999) Nature Genet , vol.23 , pp. 166-175
    • Song, W.-J.1    Sullivan, M.G.2    Legare, R.D.3
  • 12
    • 0035525785 scopus 로고    scopus 로고
    • A novel CBFA2 single-nucleotide mutation in familial platelet disorder with propensity to develop myeloid malignancies
    • Buijs A, Poddighe P, van Wilk R, et al. A novel CBFA2 single-nucleotide mutation in familial platelet disorder with propensity to develop myeloid malignancies. Blood. 2001;98:2856-2858.
    • (2001) Blood , vol.98 , pp. 2856-2858
    • Buijs, A.1    Poddighe, P.2    Van Wilk, R.3
  • 13
    • 0035066381 scopus 로고    scopus 로고
    • The leukemia-associated AML1 (Runxl)-CBFβ complex functions as a DNA-induced molecular clamp
    • Bravo J, Li Z, Speck NA, Warren AJ. The leukemia-associated AML1 (Runxl)-CBFβ complex functions as a DNA-induced molecular clamp. Nat Struct Biol. 2001;8:371-378.
    • (2001) Nat Struct Biol , vol.8 , pp. 371-378
    • Bravo, J.1    Li, Z.2    Speck, N.A.3    Warren, A.J.4
  • 14
    • 0035831044 scopus 로고    scopus 로고
    • Structural analysis of DNA recognition by the AML1/ Runx-1 runt domain and its allosteric control by CBFβ
    • Tahirov TH, Inoue-Bungo T, Morii H, et al. Structural analysis of DNA recognition by the AML1/ Runx-1 runt domain and its allosteric control by CBFβ. Cell. 2001;104:755-767.
    • (2001) Cell , vol.104 , pp. 755-767
    • Tahirov, T.H.1    Inoue-Bungo, T.2    Morii, H.3
  • 15
    • 0033569711 scopus 로고    scopus 로고
    • The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains
    • Berardi MJ, Sun C, Zehr M, et al. The Ig fold of the core binding factor alpha Runt domain is a member of a family of structurally and functionally related Ig-fold DNA-binding domains. Structure Fold Des. 1999;7:1247-1256.
    • (1999) Structure Fold Des , vol.7 , pp. 1247-1256
    • Berardi, M.J.1    Sun, C.2    Zehr, M.3
  • 16
    • 0032984118 scopus 로고    scopus 로고
    • Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain
    • Nagata T, Gupta V, Sorce D, et al. Immunoglobulin motif DNA recognition and heterodimerization of the PEBP2/CBF Runt domain. Nat Struct Biol. 1999;7:615-619.
    • (1999) Nat Struct Biol , vol.7 , pp. 615-619
    • Nagata, T.1    Gupta, V.2    Sorce, D.3
  • 17
    • 0030898006 scopus 로고    scopus 로고
    • Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus
    • Stanulla M, Wang J, Chervinsky DS, Aplan PD. Topoisomerase II inhibitors induce DNA double-strand breaks at a specific site within the AML1 locus. Leukemia. 1997;11:490-496.
    • (1997) Leukemia , vol.11 , pp. 490-496
    • Stanulla, M.1    Wang, J.2    Chervinsky, D.S.3    Aplan, P.D.4
  • 19
    • 0032532643 scopus 로고    scopus 로고
    • CBFA2 (AML 1) translocations with novel partner chromosomes in myeloid leukemias: Association with prior therapy
    • Roulston D, Espinosa R III, Nucifora G, et al. CBFA2 (AML 1) translocations with novel partner chromosomes in myeloid leukemias: association with prior therapy. Blood. 1998;92:2879-2885.
    • (1998) Blood , vol.92 , pp. 2879-2885
    • Roulston, D.1    Espinosa R. III2    Nucifora, G.3
  • 20
    • 0034660204 scopus 로고    scopus 로고
    • A novel syndrome of radiation-associated acute myeloid leukemia involving AML1 gene translocations
    • Hromas R, Shopnick R, Jumean HG, Bowers C, Varella-Garcia M, Richkind K. A novel syndrome of radiation-associated acute myeloid leukemia involving AML1 gene translocations. Blood. 2000;95:4011-4013.
    • (2000) Blood , vol.95 , pp. 4011-4013
    • Hromas, R.1    Shopnick, R.2    Jumean, H.G.3    Bowers, C.4    Varella-Garcia, M.5    Richkind, K.6
  • 21
    • 85117738561 scopus 로고    scopus 로고
    • Radiation-induced leukemia
    • Finch SC. Radiation-induced leukemia [letter]. Blood. 2001;97:1897.
    • (2001) Blood , vol.97 , pp. 1897
    • Finch, S.C.1
  • 23
    • 0012377261 scopus 로고
    • US-Japan joint reassessment of atomic bomb radiation dosimetry in Hiroshima and Nagasaki, final report
    • Roesch WC. US-Japan joint reassessment of atomic bomb radiation dosimetry in Hiroshima and Nagasaki, final report. Vol 2. Hiroshima, Japan: Radiation Effects Research Foundation; 1987.
    • (1987) Vol 2. Hiroshima, Japan: Radiation Effects Research Foundation
    • Roesch, W.C.1
  • 24
    • 0025797752 scopus 로고
    • Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-M0)
    • Bennett JM, Catovsky D, Daniel M-T, et al. Proposal for the recognition of minimally differentiated acute myeloid leukaemia (AML-M0). Br J Haematol. 1991;78:325-329.
    • (1991) Br J Haematol , vol.78 , pp. 325-329
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.-T.3
  • 25
    • 0000704627 scopus 로고    scopus 로고
    • Transfection of DNA into eukaryotic cells
    • Ausubel FM, Brent R, Kingston RE, More DD, Sejdman JG, Smith JA, Struhl K, eds. New York, NY: Greene Publishing Associates and Wiley Interscience
    • Kingston RE, Chen CA, Okayama H, Rose JK. Transfection of DNA into eukaryotic cells. In: Ausubel FM, Brent R, Kingston RE, More DD, Sejdman JG, Smith JA, Struhl K, eds. Current Protocols in Molecular Biology. New York, NY: Greene Publishing Associates and Wiley Interscience; 1996:9.1.1-9.1.11.
    • (1996) Current Protocols in Molecular Biology , pp. 911-9111
    • Kingston, R.E.1    Chen, C.A.2    Okayama, H.3    Rose, J.K.4
  • 26
    • 0030024112 scopus 로고    scopus 로고
    • CCAAT enhancer-binding protein (C/EBP) and AML1 (CBFα2) synergistically activate the macrophage colony-stimulating factor receptor promoter
    • Zhang D-E, Hetherington CJ, Meyers S, et al. CCAAT enhancer-binding protein (C/EBP) and AML1 (CBFα2) synergistically activate the macrophage colony-stimulating factor receptor promoter. Mol Cell Biol. 1996;16:1231-1240.
    • (1996) Mol Cell Biol , vol.16 , pp. 1231-1240
    • Zhang, D.-E.1    Hetherington, C.J.2    Meyers, S.3
  • 27
    • 0025730640 scopus 로고
    • A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
    • Andrews NC, Faller DV. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 1991;19:2499.
    • (1991) Nucleic Acids Res , vol.19 , pp. 2499
    • Andrews, N.C.1    Faller, D.V.2
  • 28
    • 0034809605 scopus 로고    scopus 로고
    • A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1
    • Harada Y, Harada H, Downing JR, Kimura A. A hematopoietic-specific transmembrane protein, Art-1, is possibly regulated by AML1. Biochem Biophys Res Commun. 2001;284:714-722.
    • (2001) Biochem Biophys Res Commun , vol.284 , pp. 714-722
    • Harada, Y.1    Harada, H.2    Downing, J.R.3    Kimura, A.4
  • 29
    • 0012419271 scopus 로고
    • Cancer mortality rates in atomic bomb survivors
    • Shigematsu I, Ito C, Kamada N, Akiyama M, Sasaki H, eds. Tokyo, Japan: Bunkodo
    • Kato H, Shimizu Y. Cancer mortality rates in atomic bomb survivors. In: Shigematsu I, Ito C, Kamada N, Akiyama M, Sasaki H, eds. Effects of A-Bomb Radiation on the Human Body. Tokyo, Japan: Bunkodo; 1995:26-39.
    • (1995) Effects of A-Bomb Radiation on the Human Body , pp. 26-39
    • Kato, H.1    Shimizu, Y.2
  • 30
    • 0030658039 scopus 로고    scopus 로고
    • Oncogenic transcription factors in the human acute leukemias
    • Look AT. Oncogenic transcription factors in the human acute leukemias. Science. 1997;278:1059-1064.
    • (1997) Science , vol.278 , pp. 1059-1064
    • Look, A.T.1
  • 31
    • 0029917702 scopus 로고    scopus 로고
    • Cytogenetics of myelodysplastic syndrome
    • Fenaux P, Morel P, Lai JL. Cytogenetics of myelodysplastic syndrome. Semin Hematol. 1996;33:127-138.
    • (1996) Semin Hematol , vol.33 , pp. 127-138
    • Fenaux, P.1    Morel, P.2    Lai, J.L.3
  • 32
    • 0035379034 scopus 로고    scopus 로고
    • Chromosome and molecular abnormalities in myelodysplastic syndromes
    • Fenaux P. Chromosome and molecular abnormalities in myelodysplastic syndromes. Int J Hematol. 2001;73:429-437.
    • (2001) Int J Hematol , vol.73 , pp. 429-437
    • Fenaux, P.1
  • 33
    • 0023276173 scopus 로고
    • Evidence for increased somatic cell mutations at the glycophorin A locus in atomic bomb survivors
    • Langlois RG, Bigbee WL, Kyoizumi S, et al. Evidence for increased somatic cell mutations at the glycophorin A locus in atomic bomb survivors. Science. 1987;236:445-448.
    • (1987) Science , vol.236 , pp. 445-448
    • Langlois, R.G.1    Bigbee, W.L.2    Kyoizumi, S.3
  • 34
    • 0029957134 scopus 로고    scopus 로고
    • Somatic cell mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors: Implications for radiation carcinogenesis
    • Kyoizumi S, Akiyama M, Cologne JB, et al. Somatic cell mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors: implications for radiation carcinogenesis. Radiat Res. 1996;146:43-52.
    • (1996) Radiat Res , vol.146 , pp. 43-52
    • Kyoizumi, S.1    Akiyama, M.2    Cologne, J.B.3
  • 35
    • 0028871987 scopus 로고
    • Different genetic pathways in leukemogenesis for patients presenting with therapy-related myelodysplasia and therapy-related acute myeloid leukemia
    • Pedersen-Bjergaard J, Pedersen M, Roulston D, Philip P. Different genetic pathways in leukemogenesis for patients presenting with therapy-related myelodysplasia and therapy-related acute myeloid leukemia. Blood. 1995;86:3542-3552.
    • (1995) Blood , vol.86 , pp. 3542-3552
    • Pedersen-Bjergaard, J.1    Pedersen, M.2    Roulston, D.3    Philip, P.4
  • 36
    • 0035281739 scopus 로고    scopus 로고
    • Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis
    • Christiansen DH, Anderson MK, Pedersen-Biergaard J. Mutations with loss of heterozygosity of p53 are common in therapy-related myelodysplasia and acute myeloid leukemia after exposure to alkylating agents and significantly associated with deletion or loss of 5q, a complex karyotype, and a poor prognosis. J Clin Oncol. 2001;19:1405-1413.
    • (2001) J Clin Oncol , vol.19 , pp. 1405-1413
    • Christiansen, D.H.1    Anderson, M.K.2    Pedersen-Biergaard, J.3
  • 37
    • 0036186852 scopus 로고    scopus 로고
    • Mutations in the RUNX2 gene in patients with cleidocranial dysplasia
    • Otto F, Kanegane H, Mundlos S. Mutations in the RUNX2 gene in patients with cleidocranial dysplasia. Hum Mutat. 2002;19:209-216.
    • (2002) Hum Mutat , vol.19 , pp. 209-216
    • Otto, F.1    Kanegane, H.2    Mundlos, S.3


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