메뉴 건너뛰기




Volumn 28, Issue 11, 2014, Pages 2206-2212

ASXL1 and SETBP1 mutations and their prognostic contribution in chronic myelomonocytic leukemia: A two-center study of 466 patients

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; POLYCOMB GROUP PROTEIN; ASXL1 PROTEIN, HUMAN; CARRIER PROTEIN; NUCLEAR PROTEIN; REPRESSOR PROTEIN; SETBP1 PROTEIN, HUMAN; STOP CODON;

EID: 84922332658     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2014.125     Document Type: Article
Times cited : (228)

References (33)
  • 2
    • 84898488422 scopus 로고    scopus 로고
    • Chronic myelomonocytic leukaemia: A concise clinical and pathophysiological review
    • Patnaik MM, Parikh SA, Hanson CA, Tefferi A. Chronic myelomonocytic leukaemia: a concise clinical and pathophysiological review. Br J Haematol 2014;165:273-286.
    • (2014) Br J Haematol , vol.165 , pp. 273-286
    • Patnaik, M.M.1    Parikh, S.A.2    Hanson, C.A.3    Tefferi, A.4
  • 3
    • 84878947680 scopus 로고    scopus 로고
    • SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias
    • Damm F, Itzykson R, Kosmider O, Droin N, Renneville A, Chesnais V et al. SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias. Leukemia 2013;27:1401-1403.
    • (2013) Leukemia , vol.27 , pp. 1401-1403
    • Damm, F.1    Itzykson, R.2    Kosmider, O.3    Droin, N.4    Renneville, A.5    Chesnais, V.6
  • 4
    • 66849124925 scopus 로고    scopus 로고
    • Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia
    • Gelsi-Boyer V, Trouplin V, Adelaide J, Bonansea J, Cervera N, Carbuccia N et al. Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia. Br J Haematol 2009;145:788-800.
    • (2009) Br J Haematol , vol.145 , pp. 788-800
    • Gelsi-Boyer, V.1    Trouplin, V.2    Adelaide, J.3    Bonansea, J.4    Cervera, N.5    Carbuccia, N.6
  • 6
    • 84885644431 scopus 로고    scopus 로고
    • SETBP1 mutations in 415 patients with primary myelofibrosis or chronic myelomonocytic leukemia: Independent prognostic impact in CMML
    • Laborde R, Patnaik M, Lasho T, Finke C, Hanson C, Knudson R et al. SETBP1 mutations in 415 patients with primary myelofibrosis or chronic myelomonocytic leukemia: independent prognostic impact in CMML. Leukemia 2013;27:2100-2102.
    • (2013) Leukemia , vol.27 , pp. 2100-2102
    • Laborde, R.1    Patnaik, M.2    Lasho, T.3    Finke, C.4    Hanson, C.5    Knudson, R.6
  • 7
  • 8
    • 79960227474 scopus 로고    scopus 로고
    • Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms
    • Abdel-Wahab O, Pardanani A, Patel J, Wadleigh M, Lasho T, Heguy A et al. Concomitant analysis of EZH2 and ASXL1 mutations in myelofibrosis, chronic myelomonocytic leukemia and blast-phase myeloproliferative neoplasms. Leukemia 2011;25:1200-1202.
    • (2011) Leukemia , vol.25 , pp. 1200-1202
    • Abdel-Wahab, O.1    Pardanani, A.2    Patel, J.3    Wadleigh, M.4    Lasho, T.5    Heguy, A.6
  • 10
    • 84880263477 scopus 로고    scopus 로고
    • Mayo prognostic model for WHO-defined chronic myelomonocytic leukemia: ASXL1 and spliceosome component mutations and outcomes
    • Patnaik MM, Padron E, LaBorde RR, Lasho TL, Finke CM, Hanson CA et al. Mayo prognostic model for WHO-defined chronic myelomonocytic leukemia: ASXL1 and spliceosome component mutations and outcomes. Leukemia 2013;27:1504-1510.
    • (2013) Leukemia , vol.27 , pp. 1504-1510
    • Patnaik, M.M.1    Padron, E.2    LaBorde, R.R.3    Lasho, T.L.4    Finke, C.M.5    Hanson, C.A.6
  • 11
    • 84883742761 scopus 로고    scopus 로고
    • SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i (17) (q10), ASXL1 and CBL mutations
    • Meggendorfer M, Bacher U, Alpermann T, Haferlach C, Kern W, Gambacorti-Passerini C et al. SETBP1 mutations occur in 9% of MDS/MPN and in 4% of MPN cases and are strongly associated with atypical CML, monosomy 7, isochromosome i (17) (q10), ASXL1 and CBL mutations. Leukemia 2013;27:1852-1860.
    • (2013) Leukemia , vol.27 , pp. 1852-1860
    • Meggendorfer, M.1    Bacher, U.2    Alpermann, T.3    Haferlach, C.4    Kern, W.5    Gambacorti-Passerini, C.6
  • 12
  • 13
    • 0036464647 scopus 로고    scopus 로고
    • Prognostic factors and scoring systems in chronic myelomonocytic leukemia: A retrospective analysis of 213 patients
    • Onida F, Kantarjian HM, Smith TL, Ball G, Keating MJ, Estey EH et al. Prognostic factors and scoring systems in chronic myelomonocytic leukemia: a retrospective analysis of 213 patients. Blood 2002;99:840-849.
    • (2002) Blood , vol.99 , pp. 840-849
    • Onida, F.1    Kantarjian, H.M.2    Smith, T.L.3    Ball, G.4    Keating, M.J.5    Estey, E.H.6
  • 14
    • 84869786872 scopus 로고    scopus 로고
    • SRSF2 mutations in primary myelofibrosis: Significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival
    • Lasho TL, Jimma T, Finke CM, Patnaik M, Hanson CA, Ketterling RP et al. SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival. Blood 2012;120:4168-4171.
    • (2012) Blood , vol.120 , pp. 4168-4171
    • Lasho, T.L.1    Jimma, T.2    Finke, C.M.3    Patnaik, M.4    Hanson, C.A.5    Ketterling, R.P.6
  • 15
    • 84855841586 scopus 로고    scopus 로고
    • SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value
    • Patnaik MM, Lasho TL, Hodnefield JM, Knudson RA, Ketterling RP, Garcia-Manero G et al. SF3B1 mutations are prevalent in myelodysplastic syndromes with ring sideroblasts but do not hold independent prognostic value. Blood 2012;119:569-572.
    • (2012) Blood , vol.119 , pp. 569-572
    • Patnaik, M.M.1    Lasho, T.L.2    Hodnefield, J.M.3    Knudson, R.A.4    Ketterling, R.P.5    Garcia-Manero, G.6
  • 17
    • 77954581139 scopus 로고    scopus 로고
    • Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1
    • Tefferi A. Novel mutations and their functional and clinical relevance in myeloproliferative neoplasms: JAK2, MPL, TET2, ASXL1, CBL, IDH and IKZF1. Leukemia 2010;24:1128-1138.
    • (2010) Leukemia , vol.24 , pp. 1128-1138
    • Tefferi, A.1
  • 18
    • 77956440933 scopus 로고    scopus 로고
    • The most commonly reported variant in ASXL1 (c.1934dupG;p. Gly646TrpfsX12) is not a somatic alteration
    • Abdel-Wahab O, Kilpivaara O, Patel J, Busque L, Levine RL. The most commonly reported variant in ASXL1 (c.1934dupG;p. Gly646TrpfsX12) is not a somatic alteration. Leukemia 2010;24:1656-1657.
    • (2010) Leukemia , vol.24 , pp. 1656-1657
    • Abdel-Wahab, O.1    Kilpivaara, O.2    Patel, J.3    Busque, L.4    Levine, R.L.5
  • 20
    • 79959317767 scopus 로고    scopus 로고
    • Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes
    • Thol F, Friesen I, Damm F, Yun H, Weissinger EM, Krauter J et al. Prognostic significance of ASXL1 mutations in patients with myelodysplastic syndromes. J Clin Oncol 2011;29:2499-2506.
    • (2011) J Clin Oncol , vol.29 , pp. 2499-2506
    • Thol, F.1    Friesen, I.2    Damm, F.3    Yun, H.4    Weissinger, E.M.5    Krauter, J.6
  • 21
    • 77952421834 scopus 로고    scopus 로고
    • Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia
    • Boultwood J, Perry J, Pellagatti A, Fernandez-Mercado M, Fernandez-Santamaria C, Calasanz MJ et al. Frequent mutation of the polycomb-associated gene ASXL1 in the myelodysplastic syndromes and in acute myeloid leukemia. Leukemia 2010;24:1062-1065.
    • (2010) Leukemia , vol.24 , pp. 1062-1065
    • Boultwood, J.1    Perry, J.2    Pellagatti, A.3    Fernandez-Mercado, M.4    Fernandez-Santamaria, C.5    Calasanz, M.J.6
  • 26
    • 84904056081 scopus 로고    scopus 로고
    • CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: An international study of 570 patients
    • Tefferi A, Guglielmelli P, Lasho TL, Rotunno G, Finke C, Mannarelli C et al. CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: an international study of 570 patients. Leukemia 2014;28:1494-1500.
    • (2014) Leukemia , vol.28 , pp. 1494-1500
    • Tefferi, A.1    Guglielmelli, P.2    Lasho, T.L.3    Rotunno, G.4    Finke, C.5    Mannarelli, C.6
  • 27
    • 84896535727 scopus 로고    scopus 로고
    • ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases
    • Damaj G, Joris M, Chandesris O, Hanssens K, Soucie E, Canioni D et al. ASXL1 but not TET2 mutations adversely impact overall survival of patients suffering systemic mastocytosis with associated clonal hematologic non-mast-cell diseases. PLoS One 2014;9:e85362.
    • (2014) PLoS One , vol.9 , pp. e85362
    • Damaj, G.1    Joris, M.2    Chandesris, O.3    Hanssens, K.4    Soucie, E.5    Canioni, D.6
  • 28
  • 29
  • 30
    • 84873568769 scopus 로고    scopus 로고
    • ASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcome
    • Schnittger S, Eder C, Jeromin S, Alpermann T, Fasan A, Grossmann V et al. ASXL1 exon 12 mutations are frequent in AML with intermediate risk karyotype and are independently associated with an adverse outcome. Leukemia 2013;27:82-91.
    • (2013) Leukemia , vol.27 , pp. 82-91
    • Schnittger, S.1    Eder, C.2    Jeromin, S.3    Alpermann, T.4    Fasan, A.5    Grossmann, V.6
  • 31
    • 81555228423 scopus 로고    scopus 로고
    • Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia
    • Shen Y, Zhu YM, Fan X, Shi JY, Wang QR, Yan XJ et al. Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia. Blood 2011;118:5593-5603.
    • (2011) Blood , vol.118 , pp. 5593-5603
    • Shen, Y.1    Zhu, Y.M.2    Fan, X.3    Shi, J.Y.4    Wang, Q.R.5    Yan, X.J.6
  • 32
    • 84255176496 scopus 로고    scopus 로고
    • ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category
    • Metzeler KH, Becker H, Maharry K, Radmacher MD, Kohlschmidt J, Mrozek K et al. ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category. Blood 2011;118:6920-6929.
    • (2011) Blood , vol.118 , pp. 6920-6929
    • Metzeler, K.H.1    Becker, H.2    Maharry, K.3    Radmacher, M.D.4    Kohlschmidt, J.5    Mrozek, K.6
  • 33
    • 84893717057 scopus 로고    scopus 로고
    • U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype
    • Tefferi A, Finke CM, Lasho TL, Wassie EA, Knudson R, Ketterling RP et al. U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype. Leukemia 2014;28:431-433.
    • (2014) Leukemia , vol.28 , pp. 431-433
    • Tefferi, A.1    Finke, C.M.2    Lasho, T.L.3    Wassie, E.A.4    Knudson, R.5    Ketterling, R.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.