메뉴 건너뛰기




Volumn 98, Issue 1, 2013, Pages 103-108

Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR RECEPTOR 1; PONATINIB;

EID: 84872087188     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2012.066407     Document Type: Article
Times cited : (63)

References (19)
  • 1
    • 47949114797 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders
    • Cross NC, Reiter A. Fibroblast growth factor receptor and platelet-derived growth factor receptor abnormalities in eosinophilic myeloproliferative disorders. Acta Haematol. 2008;119(4):199-206.
    • (2008) Acta Haematol. , vol.119 , Issue.4 , pp. 199-206
    • Cross, N.C.1    Reiter, A.2
  • 2
    • 79958051808 scopus 로고    scopus 로고
    • The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with Tlymphoblastic leukemia/lymphoma and t(7;8)(q22;p11)
    • Wasag B, Lierman E, Meeus P, Cools J, Vandenberghe P. The kinase inhibitor TKI258 is active against the novel CUX1-FGFR1 fusion detected in a patient with Tlymphoblastic leukemia/lymphoma and t(7;8)(q22;p11). Haematologica. 2011;96(6): 922-6.
    • (2011) Haematologica. , vol.96 , Issue.6 , pp. 922-926
    • Wasag, B.1    Lierman, E.2    Meeus, P.3    Cools, J.4    Vandenberghe, P.5
  • 3
    • 1642421743 scopus 로고    scopus 로고
    • Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations
    • Roumiantsev S, Krause DS, Neumann CA, Dimitri CA, Asiedu F, Cross NC, et al. Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocations. Cancer Cell. 2004;5(3): 287-98.
    • (2004) Cancer Cell. , vol.5 , Issue.3 , pp. 287-298
    • Roumiantsev, S.1    Krause, D.S.2    Neumann, C.A.3    Dimitri, C.A.4    Asiedu, F.5    Cross, N.C.6
  • 4
    • 36348943566 scopus 로고    scopus 로고
    • Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome
    • Chase A, Grand FH, Cross NC. Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome. Blood. 2007;110(10):3729-34.
    • (2007) Blood. , vol.110 , Issue.10 , pp. 3729-3734
    • Chase, A.1    Grand, F.H.2    Cross, N.C.3
  • 5
    • 5144234541 scopus 로고    scopus 로고
    • PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder
    • Chen J, Deangelo DJ, Kutok JL, Williams IR, Lee BH, Wadleigh M, et al. PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder. Proc Natl Acad Sci USA. 2004;101(40):14479-84.
    • (2004) Proc Natl Acad Sci USA. , vol.101 , Issue.40 , pp. 14479-14484
    • Chen, J.1    Deangelo, D.J.2    Kutok, J.L.3    Williams, I.R.4    Lee, B.H.5    Wadleigh, M.6
  • 6
    • 80051474782 scopus 로고    scopus 로고
    • t(8;22)/BCR-FGFR1 myeloproliferative disorder presenting as B-acute lymphoblastic leukemia: Report of a case treated with sorafenib and review of the literature
    • Wakim JJ, Tirado CA, Chen W, Collins R. t(8;22)/BCR-FGFR1 myeloproliferative disorder presenting as B-acute lymphoblastic leukemia: report of a case treated with sorafenib and review of the literature. Leuk Res. 2011;35(9):e151-3.
    • (2011) Leuk Res. , vol.35 , Issue.9
    • Wakim, J.J.1    Tirado, C.A.2    Chen, W.3    Collins, R.4
  • 7
    • 2342566403 scopus 로고    scopus 로고
    • Targeting FGFR3 in multiple myeloma: Inhibition of t(4;14)-positive cells by SU5402 and PD173074
    • Grand EK, Chase AJ, Heath C, Rahemtulla A, Cross NC. Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074. Leukemia. 2004;18(5):962-6.
    • (2004) Leukemia. , vol.18 , Issue.5 , pp. 962-966
    • Grand, E.K.1    Chase, A.J.2    Heath, C.3    Rahemtulla, A.4    Cross, N.C.5
  • 8
    • 84859402751 scopus 로고    scopus 로고
    • Ponatinib (AP24534), a multi-targeted panFGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models
    • Gozgit JM, Wong MJ, Moran L, Wardwell S, Mohemmad QK, Narasimhan NI, et al. Ponatinib (AP24534), a multi-targeted panFGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models. Mol Cancer Ther. 2012;11(3):690-9
    • (2012) Mol Cancer Ther. , vol.11 , Issue.3 , pp. 690-699
    • Gozgit, J.M.1    Wong, M.J.2    Moran, L.3    Wardwell, S.4    Mohemmad, Q.K.5    Narasimhan, N.I.6
  • 9
    • 79958760963 scopus 로고    scopus 로고
    • Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies
    • Gozgit JM, Wong MJ, Wardwell S, Tyner JW, Loriaux MM, Mohemmad QK, et al. Potent activity of ponatinib (AP24534) in models of FLT3-driven acute myeloid leukemia and other hematologic malignancies. Mol Cancer Ther. 2011;10(6):1028-35.
    • (2011) Mol Cancer Ther. , vol.10 , Issue.6 , pp. 1028-1035
    • Gozgit, J.M.1    Wong, M.J.2    Wardwell, S.3    Tyner, J.W.4    Loriaux, M.M.5    Mohemmad, Q.K.6
  • 10
    • 70350507997 scopus 로고    scopus 로고
    • AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
    • O'Hare T, Shakespeare WC, Zhu X, Eide CA, Rivera VM, Wang F, et al. AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance. Cancer Cell. 2009;16(5):401-12.
    • (2009) Cancer Cell. , vol.16 , Issue.5 , pp. 401-412
    • O'Hare, T.1    Shakespeare, W.C.2    Zhu, X.3    Eide, C.A.4    Rivera, V.M.5    Wang, F.6
  • 11
    • 0033206227 scopus 로고    scopus 로고
    • ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5
    • Smedley D, Demiroglu A, Abdul-Rauf M, Heath C, Cooper C, Shipley J, et al. ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5. Neoplasia. 1999;1(4):349-55.
    • (1999) Neoplasia. , vol.1 , Issue.4 , pp. 349-355
    • Smedley, D.1    Demiroglu, A.2    Abdul-Rauf, M.3    Heath, C.4    Cooper, C.5    Shipley, J.6
  • 12
    • 0035895067 scopus 로고    scopus 로고
    • The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: Transforming activity and specific inhibition of FGFR1 fusion proteins
    • Demiroglu A, Steer EJ, Heath C, Taylor K, Bentley M, Allen SL, et al. The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins. Blood. 2001;98(13):3778-83.
    • (2001) Blood. , vol.98 , Issue.13 , pp. 3778-3783
    • Demiroglu, A.1    Steer, E.J.2    Heath, C.3    Taylor, K.4    Bentley, M.5    Allen, S.L.6
  • 13
    • 0032789876 scopus 로고    scopus 로고
    • Assignment of ZNF262 to human chromosome band 1p34-->p32 by in situ hybridization
    • Sohal J, Chase A, Goldman JM, Cross NC. Assignment of ZNF262 to human chromosome band 1p34-->p32 by in situ hybridization. Cytogenet Cell Genet. 1999;85(3-4):306-7.
    • (1999) Cytogenet Cell Genet. , vol.85 , Issue.3-4 , pp. 306-307
    • Sohal, J.1    Chase, A.2    Goldman, J.M.3    Cross, N.C.4
  • 14
    • 84905515146 scopus 로고    scopus 로고
    • Identification of four new translocations involving FGFR1 in myeloid disorders
    • Sohal J, Chase A, Mould S, Corcoran M, Oscier D, Iqbal S, et al. Identification of four new translocations involving FGFR1 in myeloid disorders. Gene Chromosome Canc. 2001;32(2):155-63.
    • (2001) Gene Chromosome Canc. , vol.32 , Issue.2 , pp. 155-163
    • Sohal, J.1    Chase, A.2    Mould, S.3    Corcoran, M.4    Oscier, D.5    Iqbal, S.6
  • 15
    • 84855798616 scopus 로고    scopus 로고
    • Ponatinib: Targeting the T315I Mutation in Chronic Myelogenous Leukemia
    • Shah NP. Ponatinib: Targeting the T315I Mutation in Chronic Myelogenous Leukemia. Clin Adv Hematol Oncol. 2011; 9(12):925-6.
    • (2011) Clin Adv Hematol Oncol. , vol.9 , Issue.12 , pp. 925-926
    • Shah, N.P.1
  • 16
    • 77957007418 scopus 로고    scopus 로고
    • Caspase 3 activity in whole cell extracts of Ba/F3 cells is unrelated to apoptosis
    • Speidel D, Stocking C. Caspase 3 activity in whole cell extracts of Ba/F3 cells is unrelated to apoptosis. Cell Cycle. 2010;9(18): 3823-5.
    • (2010) Cell Cycle. , vol.9 , Issue.18 , pp. 3823-3825
    • Speidel, D.1    Stocking, C.2
  • 17
    • 33845501610 scopus 로고    scopus 로고
    • Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia
    • Gu TL, Goss VL, Reeves C, Popova L, Nardone J, Macneill J, et al. Phosphotyrosine profiling identifies the KG-1 cell line as a model for the study of FGFR1 fusions in acute myeloid leukemia. Blood. 2006;108 (13):4202-4.
    • (2006) Blood. , vol.108 , Issue.13 , pp. 4202-4204
    • Gu, T.L.1    Goss, V.L.2    Reeves, C.3    Popova, L.4    Nardone, J.5    Macneill, J.6
  • 18
    • 0031893236 scopus 로고    scopus 로고
    • Unconventional rapid Erk1,2 activation is indispensable for proliferation of the growth factor-independent myeloid leukemic cell line KG1
    • Barge RM, Dorrestijn J, Falkenburg JH, Willemze R, Maassen JA. Unconventional rapid Erk1,2 activation is indispensable for proliferation of the growth factor-independent myeloid leukemic cell line KG1. Leukemia. 1998;12(5):699-704.
    • (1998) Leukemia. , vol.12 , Issue.5 , pp. 699-704
    • Barge, R.M.1    Dorrestijn, J.2    Falkenburg, J.H.3    Willemze, R.4    Maassen, J.A.5
  • 19
    • 84863782614 scopus 로고    scopus 로고
    • Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases
    • Lierman E, Smits S, Cools J, Dewaele B, Debiec-Rychter M, Vandenberghe P. Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases. Leukemia. 2012;26(7):1693-5.
    • (2012) Leukemia. , vol.26 , Issue.7 , pp. 1693-1695
    • Lierman, E.1    Smits, S.2    Cools, J.3    Dewaele, B.4    Debiec-Rychter, M.5    Vandenberghe, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.