메뉴 건너뛰기




Volumn 94, Issue 12, 2009, Pages 1676-1681

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

(19)  Kosmider, Olivier a,b,c,d   Gelsi Boyer, Véronique e   Ciudad, Marion f,g   Racoeur, Cindy f,h   Jooste, Valérie f,g   Vey, Norbert e   Quesnel, Bruno i   Fenaux, Pierre j,k   Bastie, Jean Noël f,h   Beyne Rauzy, Odile l   Stamatoulas, Aspasia m   Dreyfus, François a,b,c,d   Ifrah, Norbert n   De Botton, Stéphane b   Vainchenker, William b   Bernard, Oliver A b   Birnbaum, Daniel e   Fontenay, Michaëla a,b,c,d   Solary, Eric b,f,h  

b INSERM   (France)
f Chu   (France)

Author keywords

Chronic myelomonocytic leukemia; Mutation; TET2 gene

Indexed keywords

GENE PRODUCT; TEN ELEVEN TRANSLOCATION 2 PROTEIN; UNCLASSIFIED DRUG;

EID: 73149094518     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2009.011205     Document Type: Article
Times cited : (216)

References (24)
  • 1
    • 0032784783 scopus 로고    scopus 로고
    • World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: Report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997
    • Harris NL, Jaffe ES, Diebold J, Flandrin G, Muller-Hermelink HK, Vardiman J, et al. World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues: report of the Clinical Advisory Committee meeting-Airlie House, Virginia, November 1997. J Clin Oncol 1999; 17:3835-49.
    • (1999) J Clin Oncol , vol.17 , pp. 3835-3849
    • Harris, N.L.1    Jaffe, E.S.2    Diebold, J.3    Flandrin, G.4    Muller-Hermelink, H.K.5    Vardiman, J.6
  • 2
    • 57249084078 scopus 로고    scopus 로고
    • Genome profiling of chronic myelomonocytic leukemia: Frequent alterations of RAS and RUNX1 genes
    • Gelsi-Boyer V, Trouplin V, Adélaïde J, Aceto N, Remy V, Pinson S, et al. Genome profiling of chronic myelomonocytic leukemia: frequent alterations of RAS and RUNX1 genes. BMC Cancer 2008;8:299.
    • (2008) BMC Cancer , vol.8 , pp. 299
    • Gelsi-Boyer, V.1    Trouplin, V.2    Adélaïde, J.3    Aceto, N.4    Remy, V.5    Pinson, S.6
  • 3
    • 68749109365 scopus 로고    scopus 로고
    • RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation
    • Kuo MC, Liang DC, Huang CF, Shih YS, Wu JH, Lin TL, et al. RUNX1 mutations are frequent in chronic myelomonocytic leukemia and mutations at the C-terminal region might predict acute myeloid leukemia transformation. Leukemia 2009;23:1426-31.
    • (2009) Leukemia , vol.23 , pp. 1426-1431
    • Kuo, M.C.1    Liang, D.C.2    Huang, C.F.3    Shih, Y.S.4    Wu, J.H.5    Lin, T.L.6
  • 4
    • 66849124925 scopus 로고    scopus 로고
    • Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia
    • Gelsi-Boyer V, Trouplin V, Adelaïde J, Bonansea J, Cervera N, Carbuccia N, et al. Mutations of polycomb-associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia. Br J Haematol 2009;145:788-800.
    • (2009) Br J Haematol , vol.145 , pp. 788-800
    • Gelsi-Boyer, V.1    Trouplin, V.2    Adelaïde, J.3    Bonansea, J.4    Cervera, N.5    Carbuccia, N.6
  • 5
    • 57749114621 scopus 로고    scopus 로고
    • 250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies
    • Dunbar AJ, Gondek LP, O'Keefe CL, Makishima H, Rataul MS, Szpurka H, et al. 250K single nucleotide polymorphism array karyotyping identifies acquired uniparental disomy and homozygous mutations, including novel missense substitutions of c-Cbl, in myeloid malignancies. Cancer Res 2008;68:10349-57.
    • (2008) Cancer Res , vol.68 , pp. 10349-10357
    • Dunbar, A.J.1    Gondek, L.P.2    O'Keefe, C.L.3    Makishima, H.4    Rataul, M.S.5    Szpurka, H.6
  • 6
    • 67650401377 scopus 로고    scopus 로고
    • Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms
    • Grand FH, Hidalgo-Curtis CE, Ernst T, Zoi K, Zoi C, McGuire C, et al. Frequent CBL mutations associated with 11q acquired uniparental disomy in myeloproliferative neoplasms. Blood 2009;113:6182-92.
    • (2009) Blood , vol.113 , pp. 6182-6192
    • Grand, F.H.1    Hidalgo-Curtis, C.E.2    Ernst, T.3    Zoi, K.4    Zoi, C.5    McGuire, C.6
  • 7
    • 61849150985 scopus 로고    scopus 로고
    • High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients
    • Tyner JW, Erickson H, Deininger MW, Willis SG, Eide CA, Levine RL, et al. High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients. Blood 2009;113:1749-55.
    • (2009) Blood , vol.113 , pp. 1749-1755
    • Tyner, J.W.1    Erickson, H.2    Deininger, M.W.3    Willis, S.G.4    Eide, C.A.5    Levine, R.L.6
  • 8
    • 47549083663 scopus 로고    scopus 로고
    • The myelodysplastic/myeloproliferative neoplasms: Myeloproliferative diseases with dysplastic features
    • Orazi A, Germing U. The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features. Leukemia 2008;22:1308-19.
    • (2008) Leukemia , vol.22 , pp. 1308-1319
    • Orazi, A.1    Germing, U.2
  • 9
    • 67349124376 scopus 로고    scopus 로고
    • TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
    • Tefferi A, Pardanani A, Lim KH, Abdel-Wahab O, Lasho TL, Patel J, et al. TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis. Leukemia 2009;23:905-11.
    • (2009) Leukemia , vol.23 , pp. 905-911
    • Tefferi, A.1    Pardanani, A.2    Lim, K.H.3    Abdel-Wahab, O.4    Lasho, T.L.5    Patel, J.6
  • 10
    • 67349145955 scopus 로고    scopus 로고
    • Frequent TET2 mutations in systemic mastocytosis: Clinical, KITD816V and FIP1L1-PDGFRA correlates
    • Tefferi A, Levine RL, Lim KH, Abdel-Wahab O, Lasho TL, Patel J, et al. Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates. Leukemia 2009;23:900-4
    • (2009) Leukemia , vol.23 , pp. 900-904
    • Tefferi, A.1    Levine, R.L.2    Lim, K.H.3    Abdel-Wahab, O.4    Lasho, T.L.5    Patel, J.6
  • 11
    • 67650924270 scopus 로고    scopus 로고
    • Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
    • Tefferi A, Lim KH, Abdel-Wahab O, Lasho TL, Patel J, Patnaik MM, et al. Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML. Leukemia 2009;23:1343-5.
    • (2009) Leukemia , vol.23 , pp. 1343-1345
    • Tefferi, A.1    Lim, K.H.2    Abdel-Wahab, O.3    Lasho, T.L.4    Patel, J.5    Patnaik, M.M.6
  • 12
    • 67650588639 scopus 로고    scopus 로고
    • Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
    • Jankowska AM, Szpurka H, Tiu RV, Makishima H, Afable M, Huh J, et al. Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms. Blood 2009;113:6403-10.
    • (2009) Blood , vol.113 , pp. 6403-6410
    • Jankowska, A.M.1    Szpurka, H.2    Tiu, R.V.3    Makishima, H.4    Afable, M.5    Huh, J.6
  • 13
    • 67651065502 scopus 로고    scopus 로고
    • Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies
    • Abdel-Wahab O, Mullally A, Hedvat C, Garcia-Manero G, Patel J, Wadleigh M, et al. Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies. Blood 2009;114:144-7.
    • (2009) Blood , vol.114 , pp. 144-147
    • Abdel-Wahab, O.1    Mullally, A.2    Hedvat, C.3    Garcia-Manero, G.4    Patel, J.5    Wadleigh, M.6
  • 17
    • 70350438115 scopus 로고    scopus 로고
    • TET2 mutation is an independent favourable prognostic factor in myelodyplastic syndromes. (MDSs)
    • Kosmider O, Gelsi-Boyer V, Cheok M, Grabar S, Della-Valle V, Picard F, et al. TET2 mutation is an independent favourable prognostic factor in myelodyplastic syndromes. (MDSs) Blood 2009;114:3285-91.
    • (2009) Blood , vol.114 , pp. 3285-3291
    • Kosmider, O.1    Gelsi-Boyer, V.2    Cheok, M.3    Grabar, S.4    Della-Valle, V.5    Picard, F.6
  • 18
    • 34347394712 scopus 로고    scopus 로고
    • Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation
    • Theocharides A, Boissinot M, Girodon F, Garand R, Teo SS, Lippert E, et al. Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation. Blood 2007;110:375-9.
    • (2007) Blood , vol.110 , pp. 375-379
    • Theocharides, A.1    Boissinot, M.2    Girodon, F.3    Garand, R.4    Teo, S.S.5    Lippert, E.6
  • 19
    • 66149146320 scopus 로고    scopus 로고
    • Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by the MLL fusion partner TET1
    • Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, et al. Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by the MLL fusion partner TET1. Science 2009;324:930-5.
    • (2009) Science , vol.324 , pp. 930-935
    • Tahiliani, M.1    Koh, K.P.2    Shen, Y.3    Pastor, W.A.4    Bandukwala, H.5    Brudno, Y.6
  • 20
    • 0036191941 scopus 로고    scopus 로고
    • Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera
    • Kralovics R, Guan Y, Prchal JT. Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol 2002;30:229-36.
    • (2002) Exp Hematol , vol.30 , pp. 229-236
    • Kralovics, R.1    Guan, Y.2    Prchal, J.T.3
  • 21
    • 0037099537 scopus 로고    scopus 로고
    • LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23)
    • Ono R, Taki T, Taketani T, Taniwaki M, Kobayashi H, Hayashi Y. LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). Cancer Res 2002;62:4075-80.
    • (2002) Cancer Res , vol.62 , pp. 4075-4080
    • Ono, R.1    Taki, T.2    Taketani, T.3    Taniwaki, M.4    Kobayashi, H.5    Hayashi, Y.6
  • 22
    • 0037350661 scopus 로고    scopus 로고
    • TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23)
    • Lorsbach RB, Moore J, Mathew S, Raimondi SC, Mukatira ST, Downing JR. TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). Leukemia 2003;17:637-41.
    • (2003) Leukemia , vol.17 , pp. 637-641
    • Lorsbach, R.B.1    Moore, J.2    Mathew, S.3    Raimondi, S.C.4    Mukatira, S.T.5    Downing, J.R.6
  • 23
    • 65449144773 scopus 로고    scopus 로고
    • The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia - results from the GMALL study group
    • Burmeister T, Meyer C, Schwartz S, Hofmann J, Molkentin M, Kowarz E, et al. The MLL recombinome of adult CD10-negative B-cell precursor acute lymphoblastic leukemia - results from the GMALL study group. Blood 2009;113:4011-5.
    • (2009) Blood , vol.113 , pp. 4011-4015
    • Burmeister, T.1    Meyer, C.2    Schwartz, S.3    Hofmann, J.4    Molkentin, M.5    Kowarz, E.6
  • 24
    • 51449109314 scopus 로고    scopus 로고
    • Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, et al. Association analysis of 528 intragenic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2008;147:727-31.
    • Morgan AR, Hamilton G, Turic D, Jehu L, Harold D, Abraham R, et al. Association analysis of 528 intragenic SNPs in a region of chromosome 10 linked to late onset Alzheimer's disease. Am J Med Genet B Neuropsychiatr Genet 2008;147:727-31.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.