Somatic activation of oncogenic Kras in hematopoietic cells initiates a rapidly fatal myeloproliferative disorder

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 2, 2004, Pages 597-602

  Braun, Benjamin S ^a   Tuveson, David A ^c   Kong, Namie ^a   Le, Doan T ^a   Kogan, Scott C ^a   Rozmus, Jacob ^a   Le Beau, Michelle M ^d   Jacks, Tyler E ^e   Shannon, Kevin M ^a,b,f  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF CHICAGO   (United States)

^e MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; K RAS G12D PROTEIN; K RAS PROTEIN; PROTEIN KINASE; RAS PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; GENE ACTIVATION; GENE EXPRESSION; GENE FUNCTION; GENE MUTATION; HEMATOPOIETIC CELL; LEUKEMIA; LEUKEMOGENESIS; MOUSE; MYELOPROLIFERATIVE DISORDER; NONHUMAN; ONCOGENE K RAS; ONCOGENE RAS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION;

ANIMALS; BONE MARROW CELLS; FLOW CYTOMETRY; GENES, RAS; KARYOTYPING; MICE; MYELOPROLIFERATIVE DISORDERS;

ANIMALIA; MURINAE;

EID: 0345743699     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0307203101     Document Type: Article

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