Myeloid neoplasms with isolated isochromosome 17q represent a clinicopathologic entity associated with myelodysplastic/myeloproliferative features, a high risk of leukemic transformation, and wild-type TP53

Cancer

Volumn 118, Issue 11, 2012, Pages 2879-2888

  Kanagal Shamanna, Rashmi ^a   Bueso Ramos, Carlos E ^a   Barkoh, Bedia ^a   Lu, Gary ^a   Wang, Sa ^a   Garcia Manero, Guillermo ^a   Vadhan Raj, Saroj ^a   Hoehn, Daniela ^a   Medeiros, L Jeffrey ^a   Yin, C Cameron ^a  

^a UNIVERSITY OF TEXAS   (United States)

Author keywords

blast transformation; isochromosome 17q; myelodysplastic; myeloid neoplasm; myeloproliferative; wild type TP53

Indexed keywords

ANTINEOPLASTIC AGENT; FLT3 LIGAND; JANUS KINASE 2; PROTEIN P53;

ACUTE GRANULOCYTIC LEUKEMIA; ADULT; AGED; ALLELE; ANEMIA; APOPTOSIS; ARTICLE; BLAST TRANSFORMATION; BONE MARROW TRANSPLANTATION; CANCER CLASSIFICATION; CANCER MORTALITY; CHROMOSOME ISOLATION; CONTROLLED STUDY; CYTOGENETICS; DISEASE ASSOCIATION; DISEASE COURSE; DNA SEQUENCE; FEMALE; FIBROSIS; HIGH RISK PATIENT; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERCELLULARITY; IMMUNOPHENOTYPING; ISOCHROMOSOME; ISOCHROMOSOME 17Q; LEUKEMIA REMISSION; LEUKEMOGENESIS; LEUKOCYTE DISORDER; LEUKOCYTOSIS; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; MICROMEGAKARYOCYTIC HYPERPLASIA; MIXED MYELODYSPLASTIC MYELOPROLIFERATIVE DISEASE; MOLECULAR GENETICS; MUTATIONAL ANALYSIS; MYELOID LEUKEMIA; ONCOGENE; ONCOGENE CEBPA; ONCOGENE FLT3; ONCOGENE JAK2; ONCOGENE KIT; ONCOGENE NPM1; ONCOGENE NRAS; ONCOGENE TP53; OSTEOSCLEROSIS; OVERALL SURVIVAL; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SPLENOMEGALY; SYMPTOMATOLOGY; THROMBOCYTOPENIA;

ADULT; AGED; AGED, 80 AND OVER; CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOMES, HUMAN, PAIR 17; FEMALE; GENES, P53; HUMANS; IMMUNOPHENOTYPING; ISOCHROMOSOMES; KARYOTYPING; LEUKEMIA, MYELOID, ACUTE; MALE; MIDDLE AGED; MYELODYSPLASTIC SYNDROMES; MYELOPROLIFERATIVE DISORDERS;

EID: 84861337785     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.26537     Document Type: Article

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