-
1
-
-
70149093912
-
Recurring mutations found by sequencing an acute myeloid leukemia genome
-
Mardis ER, Ding L, Dooling DJ, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009;361:1058-1066.
-
(2009)
N Engl J Med.
, vol.361
, pp. 1058-1066
-
-
Mardis, E.R.1
Ding, L.2
Dooling, D.J.3
-
2
-
-
78649906060
-
DNMT3A mutations in acute myeloid leukemia
-
Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363:2424-2433.
-
(2010)
N Engl J Med.
, vol.363
, pp. 2424-2433
-
-
Ley, T.J.1
Ding, L.2
Walter, M.J.3
-
3
-
-
79952381408
-
CREBBP mutations in relapsed acute lymphoblastic leukaemia
-
Mullighan CG, Zhang J, Kasper LH, et al. CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature. 2011;471(7337):235-239.
-
(2011)
Nature.
, vol.471
, Issue.7337
, pp. 235-239
-
-
Mullighan, C.G.1
Zhang, J.2
Kasper, L.H.3
-
4
-
-
79952430906
-
Inactivating mutations of acetyltransferase genes in B-cell lymphoma
-
Pasqualucci L, Dominguez-Sola D, Chiarenza A, et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature. 2011;471(7337):189-195.
-
(2011)
Nature.
, vol.471
, Issue.7337
, pp. 189-195
-
-
Pasqualucci, L.1
Dominguez-Sola, D.2
Chiarenza, A.3
-
5
-
-
80053900941
-
Frequent pathway mutations of splicing machinery in myelodysplasia
-
Yoshida K, Sanada M, Shiraishi Y, et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature. 2011;478(7367):64-69.
-
(2011)
Nature.
, vol.478
, Issue.7367
, pp. 64-69
-
-
Yoshida, K.1
Sanada, M.2
Shiraishi, Y.3
-
6
-
-
84555192302
-
Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
-
Graubert TA, Shen D, Ding L, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet. 2011;44(1):53-57.
-
(2011)
Nat Genet.
, vol.44
, Issue.1
, pp. 53-57
-
-
Graubert, T.A.1
Shen, D.2
Ding, L.3
-
7
-
-
80054010617
-
Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
-
Papaemmanuil E, Cazzola M, Boultwood J, et al. Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med. 2011;365(15):1384-1395.
-
(2011)
N Engl J Med.
, vol.365
, Issue.15
, pp. 1384-1395
-
-
Papaemmanuil, E.1
Cazzola, M.2
Boultwood, J.3
-
8
-
-
84863680893
-
Functional roles of protein splicing factors
-
Chen HC, Cheng SC. Functional roles of protein splicing factors. Biosci Rep. 2012;32(4):345-359.
-
(2012)
Biosci Rep.
, vol.32
, Issue.4
, pp. 345-359
-
-
Chen, H.C.1
Cheng, S.C.2
-
9
-
-
60349104299
-
The spliceosome: Design principles of a dynamic RNP machine
-
Wahl MC, Will CL, Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell. 2009;136:701-718.
-
(2009)
Cell.
, vol.136
, pp. 701-718
-
-
Wahl, M.C.1
Will, C.L.2
Luhrmann, R.3
-
10
-
-
84878582352
-
Regulation of splicing by SR proteins and SR proteinspecific kinases
-
Zhou Z, Fu XD. Regulation of splicing by SR proteins and SR proteinspecific kinases. Chromosoma. 2013;122(3):191-207.
-
(2013)
Chromosoma.
, vol.122
, Issue.3
, pp. 191-207
-
-
Zhou, Z.1
Fu, X.D.2
-
11
-
-
84859597590
-
Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
-
Makishima H, Visconte V, Sakaguchi H, et al. Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis. Blood. 2012;119(14):3203-3210.
-
(2012)
Blood.
, vol.119
, Issue.14
, pp. 3203-3210
-
-
Makishima, H.1
Visconte, V.2
Sakaguchi, H.3
-
12
-
-
84859856420
-
Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes
-
Thol F, Kade S, Schlarmann C, et al. Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes. Blood. 2012;119(15):3578-3584.
-
(2012)
Blood.
, vol.119
, Issue.15
, pp. 3578-3584
-
-
Thol, F.1
Kade, S.2
Schlarmann, C.3
-
13
-
-
84857994411
-
SF3B1, a splicing factor, is frequently mutated in refractory anaemia with ringed sideroblasts
-
Visconte V, Makishima H, Jankowska A, et al. SF3B1, a splicing factor, is frequently mutated in refractory anaemia with ringed sideroblasts. Leukemia. 2011;26:542-545.
-
(2011)
Leukemia.
, vol.26
, pp. 542-545
-
-
Visconte, V.1
Makishima, H.2
Jankowska, A.3
-
14
-
-
84874303759
-
Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: Prevalence, clinical correlates, and prognostic relevance
-
Patnaik MM, Lasho TL, Finke CM, et al. Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance. Am J Hematol. 2013;88(3):201-206.
-
(2013)
Am J Hematol.
, vol.88
, Issue.3
, pp. 201-206
-
-
Patnaik, M.M.1
Lasho, T.L.2
Finke, C.M.3
-
15
-
-
84872085802
-
Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia
-
Abu Kar S, Jankowska A, Makishima H, et al. Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia. Haematologica. 2013;98:107-113.
-
(2013)
Haematologica
, vol.98
, pp. 107-113
-
-
Abu Kar, S.1
Jankowska, A.2
Makishima, H.3
-
16
-
-
84858672060
-
Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML
-
Hirabayashi S, Flotho C, Moetter J, et al. Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML. Blood. 2012;119(11):e96-99.
-
(2012)
Blood.
, vol.119
, Issue.11
-
-
Hirabayashi, S.1
Flotho, C.2
Moetter, J.3
-
17
-
-
84867801670
-
The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution
-
Wu SJ, Kuo YY, Hou HA, et al. The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution. Blood. 2012;120:3106-3111.
-
(2012)
Blood.
, vol.120
, pp. 3106-3111
-
-
Wu, S.J.1
Kuo, Y.Y.2
Hou, H.A.3
-
18
-
-
84869786872
-
SRSF2 mutations in primary myelofibrosis: Significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival
-
Lasho TL, Jimma T, Finke CM, et al. SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival. Blood. 2012;120:4168-4171.
-
(2012)
Blood.
, vol.120
, pp. 4168-4171
-
-
Lasho, T.L.1
Jimma, T.2
Finke, C.M.3
-
19
-
-
84874102335
-
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
-
Landau DA, Carter SL, Stojanov P, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell. 2013;152(4):714-726.
-
(2013)
Cell.
, vol.152
, Issue.4
, pp. 714-726
-
-
Landau, D.A.1
Carter, S.L.2
Stojanov, P.3
-
20
-
-
84255160977
-
Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness
-
Rossi D, Bruscaggin A, Spina V, et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness. Blood. 2011;118:6904-6908.
-
(2011)
Blood.
, vol.118
, pp. 6904-6908
-
-
Rossi, D.1
Bruscaggin, A.2
Spina, V.3
-
21
-
-
84879173666
-
TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: Six-year follow-up of the GCLLSG CLL3X trial
-
Dreger P, Schnaiter A, Zenz T, et al. TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: six-year follow-up of the GCLLSG CLL3X trial. Blood. 2013;121(16):3284-3288.
-
(2013)
Blood.
, vol.121
, Issue.16
, pp. 3284-3288
-
-
Dreger, P.1
Schnaiter, A.2
Zenz, T.3
-
22
-
-
84855370035
-
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
-
Wang L, Lawrence MS, Wan L, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med. 2011;365(26):2497-2506.
-
(2011)
N Engl J Med.
, vol.365
, Issue.26
, pp. 2497-2506
-
-
Wang, L.1
Lawrence, M.S.2
Wan, L.3
-
23
-
-
84555171449
-
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
-
Quesada V, Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet. 2012;44(1):47-54.
-
(2012)
Nat Genet.
, vol.44
, Issue.1
, pp. 47-54
-
-
Quesada, V.1
Conde, L.2
Villamor, N.3
-
24
-
-
84872469222
-
The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
-
Oscier DG, Rose-Zerilli MJ, Winkelmann N, et al. The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial. Blood. 2013;121(3):468-475.
-
(2013)
Blood.
, vol.121
, Issue.3
, pp. 468-475
-
-
Oscier, D.G.1
Rose-Zerilli, M.J.2
Winkelmann, N.3
-
25
-
-
84862854953
-
Chronic lymphocytic leukemia with SF3B1 mutation
-
Quesada V, Ramsay AJ, Lopez-Otin C. Chronic lymphocytic leukemia with SF3B1 mutation. N Engl J Med. 2012;366(26):2530.
-
(2012)
N Engl J Med.
, vol.366
, Issue.26
, pp. 2530
-
-
Quesada, V.1
Ramsay, A.J.2
Lopez-Otin, C.3
-
26
-
-
41949123666
-
Potentially oncogenic B-cell activationinduced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL
-
Brown PJ, Ashe SL, Leich E, et al. Potentially oncogenic B-cell activationinduced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL. Blood. 2008;111(5):2816-2824.
-
(2008)
Blood.
, vol.111
, Issue.5
, pp. 2816-2824
-
-
Brown, P.J.1
Ashe, S.L.2
Leich, E.3
-
27
-
-
84859216598
-
Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
-
Molenaar JJ, Koster J, Zwijnenburg DA, et al. Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature. 2012;483(7391):589-593.
-
(2012)
Nature.
, vol.483
, Issue.7391
, pp. 589-593
-
-
Molenaar, J.J.1
Koster, J.2
Zwijnenburg, D.A.3
-
28
-
-
84869091997
-
Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
-
Biankin AV, Waddell N, Kassahn KS, et al. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature. 2012;491(7424):399- 405.
-
(2012)
Nature.
, vol.491
, Issue.7424
, pp. 399-405
-
-
Biankin, A.V.1
Waddell, N.2
Kassahn, K.S.3
-
29
-
-
84862584058
-
Whole-genome analysis informs breast cancer response to aromatase inhibition
-
Ellis MJ, Ding L, Shen D, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 2012;486(7403):353-360.
-
(2012)
Nature.
, vol.486
, Issue.7403
, pp. 353-360
-
-
Ellis, M.J.1
Ding, L.2
Shen, D.3
-
30
-
-
84861576201
-
The landscape of cancer genes and mutational processes in breast cancer
-
Stephens PJ, Tarpey PS, Davies H, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature. 2012;486(7403):400-404.
-
(2012)
Nature.
, vol.486
, Issue.7403
, pp. 400-404
-
-
Stephens, P.J.1
Tarpey, P.S.2
Davies, H.3
-
31
-
-
84862523863
-
Sequence analysis of mutations and translocations across breast cancer subtypes
-
Banerji S, Cibulskis K, Rangel-Escareno C, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 2012;486(7403):405-409.
-
(2012)
Nature.
, vol.486
, Issue.7403
, pp. 405-409
-
-
Banerji, S.1
Cibulskis, K.2
Rangel-Escareno, C.3
-
32
-
-
84882958819
-
Cancer genome atlas network. Comprehensive molecular portraits of human breast tumours
-
Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490(7418):61-70.
-
(2012)
Nature.
, vol.490
, Issue.7418
, pp. 61-70
-
-
-
33
-
-
84873086305
-
Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
-
Harbour JW, Roberson ED, Anbunathan H, et al. Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma. Nat Genet. 2013;45(2):133-135.
-
(2013)
Nat Genet.
, vol.45
, Issue.2
, pp. 133-135
-
-
Harbour, J.W.1
Roberson, E.D.2
Anbunathan, H.3
-
34
-
-
78649700287
-
Frequent mutation of BAP1 in metastasizing uveal melanomas
-
Harbour JW, Onken MD, Roberson ED, et al. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science. 2010;330(6009):1410-1413.
-
(2010)
Science.
, vol.330
, Issue.6009
, pp. 1410-1413
-
-
Harbour, J.W.1
Onken, M.D.2
Roberson, E.D.3
-
35
-
-
84865684161
-
Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
-
Krauthammer M, Kong Y, Ha BH, et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet. 2012;44(9):1006-1014.
-
(2012)
Nat Genet.
, vol.44
, Issue.9
, pp. 1006-1014
-
-
Krauthammer, M.1
Kong, Y.2
Ha, B.H.3
-
36
-
-
84877905313
-
Lack of SF3B1 R625 mutations in cutaneous melanoma
-
Schilling B, Bielefeld N, Sucker A, et al. Lack of SF3B1 R625 mutations in cutaneous melanoma. Diagn Pathol. 2013;8(1):87.
-
(2013)
Diagn Pathol.
, vol.8
, Issue.1
, pp. 87
-
-
Schilling, B.1
Bielefeld, N.2
Sucker, A.3
-
37
-
-
84866410479
-
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
-
Imielinski M, Berger AH, Hammerman PS, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 2012;150(6):1107-1120.
-
(2012)
Cell.
, vol.150
, Issue.6
, pp. 1107-1120
-
-
Imielinski, M.1
Berger, A.H.2
Hammerman, P.S.3
-
38
-
-
84858446718
-
Regulation of cytoplasmic mRNA decay
-
Schoenberg DR, Maquat LE. Regulation of cytoplasmic mRNA decay. Nat Rev Genet. 2012;13(4):246-259.
-
(2012)
Nat Rev Genet.
, vol.13
, Issue.4
, pp. 246-259
-
-
Schoenberg, D.R.1
Maquat, L.E.2
-
39
-
-
84862064202
-
The zebrafish sf3b1b460 mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development
-
An M, Henion PD. The zebrafish sf3b1b460 mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development. Int J Dev Biol. 2012;56(4):223-237.
-
(2012)
Int J Dev Biol.
, vol.56
, Issue.4
, pp. 223-237
-
-
An, M.1
Henion, P.D.2
-
40
-
-
14644431836
-
Mammalian polycombmediated repression of Hox genes requires the essential spliceosomal protein Sf3b1
-
Isono K, Mizutani-Koseki Y, Komori T, et al. Mammalian Polycombmediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. Genes Dev. 2005;19:536-541.
-
(2005)
Genes Dev.
, vol.19
, pp. 536-541
-
-
Isono, K.1
Mizutani-Koseki, Y.2
Komori, T.3
-
41
-
-
84868091622
-
SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes
-
Visconte V, Rogers HJ, Singh J, et al. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes. Blood. 2012;120:3173-3186.
-
(2012)
Blood.
, vol.120
, pp. 3173-3186
-
-
Visconte, V.1
Rogers, H.J.2
Singh, J.3
-
42
-
-
84868355027
-
The spliceosome as a target of novel antitumour drugs
-
Bonnal S, Vigevani L, Valcarcel J. The spliceosome as a target of novel antitumour drugs. Nat Rev Drug Discov. 2012;11(11):847-859.
-
(2012)
Nat Rev Drug Discov.
, vol.11
, Issue.11
, pp. 847-859
-
-
Bonnal, S.1
Vigevani, L.2
Valcarcel, J.3
-
43
-
-
34548104659
-
Splicing factor SF3b as a target of the antitumor natural product pladienolide
-
Kotake Y, Sagane K, Owa T, et al. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol. 2007;3(9): 570-575.
-
(2007)
Nat Chem Biol.
, vol.3
, Issue.9
, pp. 570-575
-
-
Kotake, Y.1
Sagane, K.2
Owa, T.3
-
44
-
-
34548095157
-
Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
-
Kaida D, Motoyoshi H, Tashiro E, et al. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol. 2007;3(9):576-583.
-
(2007)
Nat Chem Biol.
, vol.3
, Issue.9
, pp. 576-583
-
-
Kaida, D.1
Motoyoshi, H.2
Tashiro, E.3
-
45
-
-
84878061031
-
Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells
-
Gao Y, Koide K. Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells. ACS Chem Biol. 2013;8(5):895-900.
-
(2013)
ACS Chem Biol.
, vol.8
, Issue.5
, pp. 895-900
-
-
Gao, Y.1
Koide, K.2
-
46
-
-
82755192848
-
Biological validation that SF3b is a target of the antitumor macrolide pladienolide
-
Yokoi A, Kotake Y, Takahashi K, et al. Biological validation that SF3b is a target of the antitumor macrolide pladienolide. FEBS J. 2011;278(24):4870- 4880.
-
(2011)
FEBS J.
, vol.278
, Issue.24
, pp. 4870-4880
-
-
Yokoi, A.1
Kotake, Y.2
Takahashi, K.3
-
47
-
-
77955894067
-
Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
-
Hua Y, Sahashi K, Hung G, et al. Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes Dev. 2010;24(15):1634-1644.
-
(2010)
Genes Dev.
, vol.24
, Issue.15
, pp. 1634-1644
-
-
Hua, Y.1
Sahashi, K.2
Hung, G.3
-
48
-
-
0028061671
-
Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit
-
Jenny A, Hauri HP, Keller W. Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit. Mol Cell Biol. 1994;14:8183-8190.
-
(1994)
Mol Cell Biol.
, vol.14
, pp. 8183-8190
-
-
Jenny, A.1
Hauri, H.P.2
Keller, W.3
-
49
-
-
35449007714
-
The DDX3 subfamily of the DEAD box helicases: Divergent roles as unveiled by studying different organisms and in vitro assays
-
Rosner A, Rinkevich B. The DDX3 subfamily of the DEAD box helicases: divergent roles as unveiled by studying different organisms and in vitro assays. Curr Med Chem. 2007;14:2517-2525.
-
(2007)
Curr Med Chem.
, vol.14
, pp. 2517-2525
-
-
Rosner, A.1
Rinkevich, B.2
-
50
-
-
33947726050
-
CRM1-mediated nuclear export: To the pore and beyond
-
Hutten S, Kehlenbach RH. CRM1-mediated nuclear export: to the pore and beyond. Trends Cell Biol. 2007;17:193-201.
-
(2007)
Trends Cell Biol.
, vol.17
, pp. 193-201
-
-
Hutten, S.1
Kehlenbach, R.H.2
-
51
-
-
84880310708
-
Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia
-
Ramsay AJ, Rodriguez D, Villamor N, et al. Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia. Leukemia. 2013;27(7):1600-1603.
-
(2013)
Leukemia.
, vol.27
, Issue.7
, pp. 1600-1603
-
-
Ramsay, A.J.1
Rodriguez, D.2
Villamor, N.3
-
52
-
-
77950862042
-
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
-
Raaijmakers MH, Mukherjee S, Guo S, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 2010;464(7290):852-857.
-
(2010)
Nature.
, vol.464
, Issue.7290
, pp. 852-857
-
-
Raaijmakers, M.H.1
Mukherjee, S.2
Guo, S.3
-
53
-
-
77956270732
-
MicroRNA miR-125a controls hematopoietic stem cell number
-
Guo S, Lu J, Schlanger R, et al. MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci U S A. 2010;107(32):14229-14234.
-
(2010)
Proc Natl Acad Sci U S A.
, vol.107
, Issue.32
, pp. 14229-14234
-
-
Guo, S.1
Lu, J.2
Schlanger, R.3
-
54
-
-
0037229094
-
Mutations in SBDS are associated with Shwachman-Diamond syndrome
-
Boocock GR, Morrison JA, Popovic M, et al. Mutations in SBDS are associated with Shwachman-Diamond syndrome. Nat Genet. 2003;33(1): 97-101.
-
(2003)
Nat Genet.
, vol.33
, Issue.1
, pp. 97-101
-
-
Boocock, G.R.1
Morrison, J.A.2
Popovic, M.3
-
55
-
-
84864744041
-
Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients
-
Santamaria C, Muntion S, Roson B, et al. Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients. Haematologica. 2012;97(8): 1218-1224.
-
(2012)
Haematologica.
, vol.97
, Issue.8
, pp. 1218-1224
-
-
Santamaria, C.1
Muntion, S.2
Roson, B.3
-
56
-
-
0034141475
-
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
-
Kung AL, Rebel VI, Bronson RT, et al. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 2000;14(3):272-277.
-
(2000)
Genes Dev.
, vol.14
, Issue.3
, pp. 272-277
-
-
Kung, A.L.1
Rebel, V.I.2
Bronson, R.T.3
-
57
-
-
0037069424
-
Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal
-
Rebel VI, Kung AL, Tanner EA, et al. Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal. Proc Natl Acad Sci U S A. 2002;99(23):14789-14794.
-
(2002)
Proc Natl Acad Sci U S A.
, vol.99
, Issue.23
, pp. 14789-14794
-
-
Rebel, V.I.1
Kung, A.L.2
Tanner, E.A.3
-
58
-
-
79960139808
-
Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis
-
Zimmer SN, Zhou Q, Zhou T, et al. Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis. Blood. 2011;118(1):69-79.
-
(2011)
Blood.
, vol.118
, Issue.1
, pp. 69-79
-
-
Zimmer, S.N.1
Zhou, Q.2
Zhou, T.3
-
59
-
-
12644314103
-
MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16) (q23;p13.3)
-
Sobulo OM, Borrow J, Tomek R, et al. MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16) (q23;p13.3). Proc Natl Acad Sci U S A. 1997;94(16):8732-8737.
-
(1997)
Proc Natl Acad Sci U S A.
, vol.94
, Issue.16
, pp. 8732-8737
-
-
Sobulo, O.M.1
Borrow, J.2
Tomek, R.3
-
60
-
-
0034282527
-
Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia
-
Lavau C, Du C, Thirman M, et al. Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia. EMBO J. 2000;19(17):4655-4664.
-
(2000)
EMBO J.
, vol.19
, Issue.17
, pp. 4655-4664
-
-
Lavau, C.1
Du, C.2
Thirman, M.3
-
61
-
-
70349256226
-
The 2008 revision of the world health organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
-
Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937-951.
-
(2009)
Blood.
, vol.114
, Issue.5
, pp. 937-951
-
-
Vardiman, J.W.1
Thiele, J.2
Arber, D.A.3
-
62
-
-
80052083774
-
Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells
-
Lemieux ME, Cheng Z, Zhou Q, et al. Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells. PLoS One. 2011;6(8):e24153.
-
(2011)
PLoS One.
, vol.6
, Issue.8
-
-
Lemieux, M.E.1
Cheng, Z.2
Zhou, Q.3
-
63
-
-
84862805858
-
Mice heterozygous for CREB binding protein are hypersensitive to gamma-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm
-
e5
-
Zimmer SN, Lemieux ME, Karia BP, et al. Mice heterozygous for CREB binding protein are hypersensitive to gamma-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm. Exp Hematol. 2012;40(4):295-306 e5.
-
(2012)
Exp Hematol.
, vol.40
, Issue.4
, pp. 295-306
-
-
Zimmer, S.N.1
Lemieux, M.E.2
Karia, B.P.3
-
64
-
-
9144224451
-
Processing of primary microRNAs by the Microprocessor complex
-
Denli AM, Tops BB, Plasterk RH, et al. Processing of primary microRNAs by the Microprocessor complex. Nature. 2004;432(7014):231-235.
-
(2004)
Nature.
, vol.432
, Issue.7014
, pp. 231-235
-
-
Denli, A.M.1
Tops, B.B.2
Plasterk, R.H.3
-
65
-
-
77955431522
-
Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
-
Kharas MG, Lengner CJ, Al-Shahrour F, et al. Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nat Med. 2010;16(8):903-908.
-
(2010)
Nat Med.
, vol.16
, Issue.8
, pp. 903-908
-
-
Kharas, M.G.1
Lengner, C.J.2
Al-Shahrour, F.3
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