메뉴 건너뛰기




Volumn 105, Issue 20, 2013, Pages 1540-1549

Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors

Author keywords

[No Author keywords available]

Indexed keywords

6 FORMYLAMINO 12,13 DIHYDRO 1,11 DIHYDROXY 5H INDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE 5,7(6H) DIONE 13 GLUCOSIDE; AMILORIDE; CHLORHEXIDINE; MESSENGER RNA; PROTEIN INHIBITOR; RIBONUCLEOPROTEIN; SERINE ARGININE RICH PROTEIN; SERINE ARGININE RICH PROTEIN INHIBITOR; UNCLASSIFIED DRUG;

EID: 84885967382     PISSN: 00278874     EISSN: 14602105     Source Type: Journal    
DOI: 10.1093/jnci/djt257     Document Type: Review
Times cited : (65)

References (65)
  • 1
    • 70149093912 scopus 로고    scopus 로고
    • Recurring mutations found by sequencing an acute myeloid leukemia genome
    • Mardis ER, Ding L, Dooling DJ, et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. N Engl J Med. 2009;361:1058-1066.
    • (2009) N Engl J Med. , vol.361 , pp. 1058-1066
    • Mardis, E.R.1    Ding, L.2    Dooling, D.J.3
  • 2
    • 78649906060 scopus 로고    scopus 로고
    • DNMT3A mutations in acute myeloid leukemia
    • Ley TJ, Ding L, Walter MJ, et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med. 2010;363:2424-2433.
    • (2010) N Engl J Med. , vol.363 , pp. 2424-2433
    • Ley, T.J.1    Ding, L.2    Walter, M.J.3
  • 3
    • 79952381408 scopus 로고    scopus 로고
    • CREBBP mutations in relapsed acute lymphoblastic leukaemia
    • Mullighan CG, Zhang J, Kasper LH, et al. CREBBP mutations in relapsed acute lymphoblastic leukaemia. Nature. 2011;471(7337):235-239.
    • (2011) Nature. , vol.471 , Issue.7337 , pp. 235-239
    • Mullighan, C.G.1    Zhang, J.2    Kasper, L.H.3
  • 4
    • 79952430906 scopus 로고    scopus 로고
    • Inactivating mutations of acetyltransferase genes in B-cell lymphoma
    • Pasqualucci L, Dominguez-Sola D, Chiarenza A, et al. Inactivating mutations of acetyltransferase genes in B-cell lymphoma. Nature. 2011;471(7337):189-195.
    • (2011) Nature. , vol.471 , Issue.7337 , pp. 189-195
    • Pasqualucci, L.1    Dominguez-Sola, D.2    Chiarenza, A.3
  • 5
    • 80053900941 scopus 로고    scopus 로고
    • Frequent pathway mutations of splicing machinery in myelodysplasia
    • Yoshida K, Sanada M, Shiraishi Y, et al. Frequent pathway mutations of splicing machinery in myelodysplasia. Nature. 2011;478(7367):64-69.
    • (2011) Nature. , vol.478 , Issue.7367 , pp. 64-69
    • Yoshida, K.1    Sanada, M.2    Shiraishi, Y.3
  • 6
    • 84555192302 scopus 로고    scopus 로고
    • Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes
    • Graubert TA, Shen D, Ding L, et al. Recurrent mutations in the U2AF1 splicing factor in myelodysplastic syndromes. Nat Genet. 2011;44(1):53-57.
    • (2011) Nat Genet. , vol.44 , Issue.1 , pp. 53-57
    • Graubert, T.A.1    Shen, D.2    Ding, L.3
  • 7
    • 80054010617 scopus 로고    scopus 로고
    • Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts
    • Papaemmanuil E, Cazzola M, Boultwood J, et al. Somatic SF3B1 mutation in myelodysplasia with ring sideroblasts. N Engl J Med. 2011;365(15):1384-1395.
    • (2011) N Engl J Med. , vol.365 , Issue.15 , pp. 1384-1395
    • Papaemmanuil, E.1    Cazzola, M.2    Boultwood, J.3
  • 8
    • 84863680893 scopus 로고    scopus 로고
    • Functional roles of protein splicing factors
    • Chen HC, Cheng SC. Functional roles of protein splicing factors. Biosci Rep. 2012;32(4):345-359.
    • (2012) Biosci Rep. , vol.32 , Issue.4 , pp. 345-359
    • Chen, H.C.1    Cheng, S.C.2
  • 9
    • 60349104299 scopus 로고    scopus 로고
    • The spliceosome: Design principles of a dynamic RNP machine
    • Wahl MC, Will CL, Luhrmann R. The spliceosome: design principles of a dynamic RNP machine. Cell. 2009;136:701-718.
    • (2009) Cell. , vol.136 , pp. 701-718
    • Wahl, M.C.1    Will, C.L.2    Luhrmann, R.3
  • 10
    • 84878582352 scopus 로고    scopus 로고
    • Regulation of splicing by SR proteins and SR proteinspecific kinases
    • Zhou Z, Fu XD. Regulation of splicing by SR proteins and SR proteinspecific kinases. Chromosoma. 2013;122(3):191-207.
    • (2013) Chromosoma. , vol.122 , Issue.3 , pp. 191-207
    • Zhou, Z.1    Fu, X.D.2
  • 11
    • 84859597590 scopus 로고    scopus 로고
    • Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis
    • Makishima H, Visconte V, Sakaguchi H, et al. Mutations in the spliceosome machinery, a novel and ubiquitous pathway in leukemogenesis. Blood. 2012;119(14):3203-3210.
    • (2012) Blood. , vol.119 , Issue.14 , pp. 3203-3210
    • Makishima, H.1    Visconte, V.2    Sakaguchi, H.3
  • 12
    • 84859856420 scopus 로고    scopus 로고
    • Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes
    • Thol F, Kade S, Schlarmann C, et al. Frequency and prognostic impact of mutations in SRSF2, U2AF1, and ZRSR2 in patients with myelodysplastic syndromes. Blood. 2012;119(15):3578-3584.
    • (2012) Blood. , vol.119 , Issue.15 , pp. 3578-3584
    • Thol, F.1    Kade, S.2    Schlarmann, C.3
  • 13
    • 84857994411 scopus 로고    scopus 로고
    • SF3B1, a splicing factor, is frequently mutated in refractory anaemia with ringed sideroblasts
    • Visconte V, Makishima H, Jankowska A, et al. SF3B1, a splicing factor, is frequently mutated in refractory anaemia with ringed sideroblasts. Leukemia. 2011;26:542-545.
    • (2011) Leukemia. , vol.26 , pp. 542-545
    • Visconte, V.1    Makishima, H.2    Jankowska, A.3
  • 14
    • 84874303759 scopus 로고    scopus 로고
    • Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: Prevalence, clinical correlates, and prognostic relevance
    • Patnaik MM, Lasho TL, Finke CM, et al. Spliceosome mutations involving SRSF2, SF3B1, and U2AF35 in chronic myelomonocytic leukemia: prevalence, clinical correlates, and prognostic relevance. Am J Hematol. 2013;88(3):201-206.
    • (2013) Am J Hematol. , vol.88 , Issue.3 , pp. 201-206
    • Patnaik, M.M.1    Lasho, T.L.2    Finke, C.M.3
  • 15
    • 84872085802 scopus 로고    scopus 로고
    • Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia
    • Abu Kar S, Jankowska A, Makishima H, et al. Spliceosomal gene mutations are frequent events in the diverse mutational spectrum of chronic myelomonocytic leukemia but largely absent in juvenile myelomonocytic leukemia. Haematologica. 2013;98:107-113.
    • (2013) Haematologica , vol.98 , pp. 107-113
    • Abu Kar, S.1    Jankowska, A.2    Makishima, H.3
  • 16
    • 84858672060 scopus 로고    scopus 로고
    • Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML
    • Hirabayashi S, Flotho C, Moetter J, et al. Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML. Blood. 2012;119(11):e96-99.
    • (2012) Blood. , vol.119 , Issue.11
    • Hirabayashi, S.1    Flotho, C.2    Moetter, J.3
  • 17
    • 84867801670 scopus 로고    scopus 로고
    • The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution
    • Wu SJ, Kuo YY, Hou HA, et al. The clinical implication of SRSF2 mutation in patients with myelodysplastic syndrome and its stability during disease evolution. Blood. 2012;120:3106-3111.
    • (2012) Blood. , vol.120 , pp. 3106-3111
    • Wu, S.J.1    Kuo, Y.Y.2    Hou, H.A.3
  • 18
    • 84869786872 scopus 로고    scopus 로고
    • SRSF2 mutations in primary myelofibrosis: Significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival
    • Lasho TL, Jimma T, Finke CM, et al. SRSF2 mutations in primary myelofibrosis: significant clustering with IDH mutations and independent association with inferior overall and leukemia-free survival. Blood. 2012;120:4168-4171.
    • (2012) Blood. , vol.120 , pp. 4168-4171
    • Lasho, T.L.1    Jimma, T.2    Finke, C.M.3
  • 19
    • 84874102335 scopus 로고    scopus 로고
    • Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
    • Landau DA, Carter SL, Stojanov P, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell. 2013;152(4):714-726.
    • (2013) Cell. , vol.152 , Issue.4 , pp. 714-726
    • Landau, D.A.1    Carter, S.L.2    Stojanov, P.3
  • 20
    • 84255160977 scopus 로고    scopus 로고
    • Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: Association with progression and fludarabine-refractoriness
    • Rossi D, Bruscaggin A, Spina V, et al. Mutations of the SF3B1 splicing factor in chronic lymphocytic leukemia: association with progression and fludarabine-refractoriness. Blood. 2011;118:6904-6908.
    • (2011) Blood. , vol.118 , pp. 6904-6908
    • Rossi, D.1    Bruscaggin, A.2    Spina, V.3
  • 21
    • 84879173666 scopus 로고    scopus 로고
    • TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: Six-year follow-up of the GCLLSG CLL3X trial
    • Dreger P, Schnaiter A, Zenz T, et al. TP53, SF3B1, and NOTCH1 mutations and outcome of allotransplantation for chronic lymphocytic leukemia: six-year follow-up of the GCLLSG CLL3X trial. Blood. 2013;121(16):3284-3288.
    • (2013) Blood. , vol.121 , Issue.16 , pp. 3284-3288
    • Dreger, P.1    Schnaiter, A.2    Zenz, T.3
  • 22
    • 84855370035 scopus 로고    scopus 로고
    • SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
    • Wang L, Lawrence MS, Wan L, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med. 2011;365(26):2497-2506.
    • (2011) N Engl J Med. , vol.365 , Issue.26 , pp. 2497-2506
    • Wang, L.1    Lawrence, M.S.2    Wan, L.3
  • 23
    • 84555171449 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
    • Quesada V, Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet. 2012;44(1):47-54.
    • (2012) Nat Genet. , vol.44 , Issue.1 , pp. 47-54
    • Quesada, V.1    Conde, L.2    Villamor, N.3
  • 24
    • 84872469222 scopus 로고    scopus 로고
    • The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial
    • Oscier DG, Rose-Zerilli MJ, Winkelmann N, et al. The clinical significance of NOTCH1 and SF3B1 mutations in the UK LRF CLL4 trial. Blood. 2013;121(3):468-475.
    • (2013) Blood. , vol.121 , Issue.3 , pp. 468-475
    • Oscier, D.G.1    Rose-Zerilli, M.J.2    Winkelmann, N.3
  • 25
    • 84862854953 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia with SF3B1 mutation
    • Quesada V, Ramsay AJ, Lopez-Otin C. Chronic lymphocytic leukemia with SF3B1 mutation. N Engl J Med. 2012;366(26):2530.
    • (2012) N Engl J Med. , vol.366 , Issue.26 , pp. 2530
    • Quesada, V.1    Ramsay, A.J.2    Lopez-Otin, C.3
  • 26
    • 41949123666 scopus 로고    scopus 로고
    • Potentially oncogenic B-cell activationinduced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL
    • Brown PJ, Ashe SL, Leich E, et al. Potentially oncogenic B-cell activationinduced smaller isoforms of FOXP1 are highly expressed in the activated B cell-like subtype of DLBCL. Blood. 2008;111(5):2816-2824.
    • (2008) Blood. , vol.111 , Issue.5 , pp. 2816-2824
    • Brown, P.J.1    Ashe, S.L.2    Leich, E.3
  • 27
    • 84859216598 scopus 로고    scopus 로고
    • Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes
    • Molenaar JJ, Koster J, Zwijnenburg DA, et al. Sequencing of neuroblastoma identifies chromothripsis and defects in neuritogenesis genes. Nature. 2012;483(7391):589-593.
    • (2012) Nature. , vol.483 , Issue.7391 , pp. 589-593
    • Molenaar, J.J.1    Koster, J.2    Zwijnenburg, D.A.3
  • 28
    • 84869091997 scopus 로고    scopus 로고
    • Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes
    • Biankin AV, Waddell N, Kassahn KS, et al. Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes. Nature. 2012;491(7424):399- 405.
    • (2012) Nature. , vol.491 , Issue.7424 , pp. 399-405
    • Biankin, A.V.1    Waddell, N.2    Kassahn, K.S.3
  • 29
    • 84862584058 scopus 로고    scopus 로고
    • Whole-genome analysis informs breast cancer response to aromatase inhibition
    • Ellis MJ, Ding L, Shen D, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 2012;486(7403):353-360.
    • (2012) Nature. , vol.486 , Issue.7403 , pp. 353-360
    • Ellis, M.J.1    Ding, L.2    Shen, D.3
  • 30
    • 84861576201 scopus 로고    scopus 로고
    • The landscape of cancer genes and mutational processes in breast cancer
    • Stephens PJ, Tarpey PS, Davies H, et al. The landscape of cancer genes and mutational processes in breast cancer. Nature. 2012;486(7403):400-404.
    • (2012) Nature. , vol.486 , Issue.7403 , pp. 400-404
    • Stephens, P.J.1    Tarpey, P.S.2    Davies, H.3
  • 31
    • 84862523863 scopus 로고    scopus 로고
    • Sequence analysis of mutations and translocations across breast cancer subtypes
    • Banerji S, Cibulskis K, Rangel-Escareno C, et al. Sequence analysis of mutations and translocations across breast cancer subtypes. Nature. 2012;486(7403):405-409.
    • (2012) Nature. , vol.486 , Issue.7403 , pp. 405-409
    • Banerji, S.1    Cibulskis, K.2    Rangel-Escareno, C.3
  • 32
    • 84882958819 scopus 로고    scopus 로고
    • Cancer genome atlas network. Comprehensive molecular portraits of human breast tumours
    • Cancer Genome Atlas Network. Comprehensive molecular portraits of human breast tumours. Nature. 2012;490(7418):61-70.
    • (2012) Nature. , vol.490 , Issue.7418 , pp. 61-70
  • 33
    • 84873086305 scopus 로고    scopus 로고
    • Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
    • Harbour JW, Roberson ED, Anbunathan H, et al. Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma. Nat Genet. 2013;45(2):133-135.
    • (2013) Nat Genet. , vol.45 , Issue.2 , pp. 133-135
    • Harbour, J.W.1    Roberson, E.D.2    Anbunathan, H.3
  • 34
    • 78649700287 scopus 로고    scopus 로고
    • Frequent mutation of BAP1 in metastasizing uveal melanomas
    • Harbour JW, Onken MD, Roberson ED, et al. Frequent mutation of BAP1 in metastasizing uveal melanomas. Science. 2010;330(6009):1410-1413.
    • (2010) Science. , vol.330 , Issue.6009 , pp. 1410-1413
    • Harbour, J.W.1    Onken, M.D.2    Roberson, E.D.3
  • 35
    • 84865684161 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma
    • Krauthammer M, Kong Y, Ha BH, et al. Exome sequencing identifies recurrent somatic RAC1 mutations in melanoma. Nat Genet. 2012;44(9):1006-1014.
    • (2012) Nat Genet. , vol.44 , Issue.9 , pp. 1006-1014
    • Krauthammer, M.1    Kong, Y.2    Ha, B.H.3
  • 36
    • 84877905313 scopus 로고    scopus 로고
    • Lack of SF3B1 R625 mutations in cutaneous melanoma
    • Schilling B, Bielefeld N, Sucker A, et al. Lack of SF3B1 R625 mutations in cutaneous melanoma. Diagn Pathol. 2013;8(1):87.
    • (2013) Diagn Pathol. , vol.8 , Issue.1 , pp. 87
    • Schilling, B.1    Bielefeld, N.2    Sucker, A.3
  • 37
    • 84866410479 scopus 로고    scopus 로고
    • Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
    • Imielinski M, Berger AH, Hammerman PS, et al. Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell. 2012;150(6):1107-1120.
    • (2012) Cell. , vol.150 , Issue.6 , pp. 1107-1120
    • Imielinski, M.1    Berger, A.H.2    Hammerman, P.S.3
  • 38
    • 84858446718 scopus 로고    scopus 로고
    • Regulation of cytoplasmic mRNA decay
    • Schoenberg DR, Maquat LE. Regulation of cytoplasmic mRNA decay. Nat Rev Genet. 2012;13(4):246-259.
    • (2012) Nat Rev Genet. , vol.13 , Issue.4 , pp. 246-259
    • Schoenberg, D.R.1    Maquat, L.E.2
  • 39
    • 84862064202 scopus 로고    scopus 로고
    • The zebrafish sf3b1b460 mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development
    • An M, Henion PD. The zebrafish sf3b1b460 mutant reveals differential requirements for the sf3b1 pre-mRNA processing gene during neural crest development. Int J Dev Biol. 2012;56(4):223-237.
    • (2012) Int J Dev Biol. , vol.56 , Issue.4 , pp. 223-237
    • An, M.1    Henion, P.D.2
  • 40
    • 14644431836 scopus 로고    scopus 로고
    • Mammalian polycombmediated repression of Hox genes requires the essential spliceosomal protein Sf3b1
    • Isono K, Mizutani-Koseki Y, Komori T, et al. Mammalian Polycombmediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. Genes Dev. 2005;19:536-541.
    • (2005) Genes Dev. , vol.19 , pp. 536-541
    • Isono, K.1    Mizutani-Koseki, Y.2    Komori, T.3
  • 41
    • 84868091622 scopus 로고    scopus 로고
    • SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes
    • Visconte V, Rogers HJ, Singh J, et al. SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes. Blood. 2012;120:3173-3186.
    • (2012) Blood. , vol.120 , pp. 3173-3186
    • Visconte, V.1    Rogers, H.J.2    Singh, J.3
  • 42
    • 84868355027 scopus 로고    scopus 로고
    • The spliceosome as a target of novel antitumour drugs
    • Bonnal S, Vigevani L, Valcarcel J. The spliceosome as a target of novel antitumour drugs. Nat Rev Drug Discov. 2012;11(11):847-859.
    • (2012) Nat Rev Drug Discov. , vol.11 , Issue.11 , pp. 847-859
    • Bonnal, S.1    Vigevani, L.2    Valcarcel, J.3
  • 43
    • 34548104659 scopus 로고    scopus 로고
    • Splicing factor SF3b as a target of the antitumor natural product pladienolide
    • Kotake Y, Sagane K, Owa T, et al. Splicing factor SF3b as a target of the antitumor natural product pladienolide. Nat Chem Biol. 2007;3(9): 570-575.
    • (2007) Nat Chem Biol. , vol.3 , Issue.9 , pp. 570-575
    • Kotake, Y.1    Sagane, K.2    Owa, T.3
  • 44
    • 34548095157 scopus 로고    scopus 로고
    • Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
    • Kaida D, Motoyoshi H, Tashiro E, et al. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA. Nat Chem Biol. 2007;3(9):576-583.
    • (2007) Nat Chem Biol. , vol.3 , Issue.9 , pp. 576-583
    • Kaida, D.1    Motoyoshi, H.2    Tashiro, E.3
  • 45
    • 84878061031 scopus 로고    scopus 로고
    • Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells
    • Gao Y, Koide K. Chemical perturbation of Mcl-1 pre-mRNA splicing to induce apoptosis in cancer cells. ACS Chem Biol. 2013;8(5):895-900.
    • (2013) ACS Chem Biol. , vol.8 , Issue.5 , pp. 895-900
    • Gao, Y.1    Koide, K.2
  • 46
    • 82755192848 scopus 로고    scopus 로고
    • Biological validation that SF3b is a target of the antitumor macrolide pladienolide
    • Yokoi A, Kotake Y, Takahashi K, et al. Biological validation that SF3b is a target of the antitumor macrolide pladienolide. FEBS J. 2011;278(24):4870- 4880.
    • (2011) FEBS J. , vol.278 , Issue.24 , pp. 4870-4880
    • Yokoi, A.1    Kotake, Y.2    Takahashi, K.3
  • 47
    • 77955894067 scopus 로고    scopus 로고
    • Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model
    • Hua Y, Sahashi K, Hung G, et al. Antisense correction of SMN2 splicing in the CNS rescues necrosis in a type III SMA mouse model. Genes Dev. 2010;24(15):1634-1644.
    • (2010) Genes Dev. , vol.24 , Issue.15 , pp. 1634-1644
    • Hua, Y.1    Sahashi, K.2    Hung, G.3
  • 48
    • 0028061671 scopus 로고
    • Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit
    • Jenny A, Hauri HP, Keller W. Characterization of cleavage and polyadenylation specificity factor and cloning of its 100-kilodalton subunit. Mol Cell Biol. 1994;14:8183-8190.
    • (1994) Mol Cell Biol. , vol.14 , pp. 8183-8190
    • Jenny, A.1    Hauri, H.P.2    Keller, W.3
  • 49
    • 35449007714 scopus 로고    scopus 로고
    • The DDX3 subfamily of the DEAD box helicases: Divergent roles as unveiled by studying different organisms and in vitro assays
    • Rosner A, Rinkevich B. The DDX3 subfamily of the DEAD box helicases: divergent roles as unveiled by studying different organisms and in vitro assays. Curr Med Chem. 2007;14:2517-2525.
    • (2007) Curr Med Chem. , vol.14 , pp. 2517-2525
    • Rosner, A.1    Rinkevich, B.2
  • 50
    • 33947726050 scopus 로고    scopus 로고
    • CRM1-mediated nuclear export: To the pore and beyond
    • Hutten S, Kehlenbach RH. CRM1-mediated nuclear export: to the pore and beyond. Trends Cell Biol. 2007;17:193-201.
    • (2007) Trends Cell Biol. , vol.17 , pp. 193-201
    • Hutten, S.1    Kehlenbach, R.H.2
  • 51
    • 84880310708 scopus 로고    scopus 로고
    • Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia
    • Ramsay AJ, Rodriguez D, Villamor N, et al. Frequent somatic mutations in components of the RNA processing machinery in chronic lymphocytic leukemia. Leukemia. 2013;27(7):1600-1603.
    • (2013) Leukemia. , vol.27 , Issue.7 , pp. 1600-1603
    • Ramsay, A.J.1    Rodriguez, D.2    Villamor, N.3
  • 52
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers MH, Mukherjee S, Guo S, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 2010;464(7290):852-857.
    • (2010) Nature. , vol.464 , Issue.7290 , pp. 852-857
    • Raaijmakers, M.H.1    Mukherjee, S.2    Guo, S.3
  • 53
    • 77956270732 scopus 로고    scopus 로고
    • MicroRNA miR-125a controls hematopoietic stem cell number
    • Guo S, Lu J, Schlanger R, et al. MicroRNA miR-125a controls hematopoietic stem cell number. Proc Natl Acad Sci U S A. 2010;107(32):14229-14234.
    • (2010) Proc Natl Acad Sci U S A. , vol.107 , Issue.32 , pp. 14229-14234
    • Guo, S.1    Lu, J.2    Schlanger, R.3
  • 54
    • 0037229094 scopus 로고    scopus 로고
    • Mutations in SBDS are associated with Shwachman-Diamond syndrome
    • Boocock GR, Morrison JA, Popovic M, et al. Mutations in SBDS are associated with Shwachman-Diamond syndrome. Nat Genet. 2003;33(1): 97-101.
    • (2003) Nat Genet. , vol.33 , Issue.1 , pp. 97-101
    • Boocock, G.R.1    Morrison, J.A.2    Popovic, M.3
  • 55
    • 84864744041 scopus 로고    scopus 로고
    • Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients
    • Santamaria C, Muntion S, Roson B, et al. Impaired expression of DICER, DROSHA, SBDS and some microRNAs in mesenchymal stromal cells from myelodysplastic syndrome patients. Haematologica. 2012;97(8): 1218-1224.
    • (2012) Haematologica. , vol.97 , Issue.8 , pp. 1218-1224
    • Santamaria, C.1    Muntion, S.2    Roson, B.3
  • 56
    • 0034141475 scopus 로고    scopus 로고
    • Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
    • Kung AL, Rebel VI, Bronson RT, et al. Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev. 2000;14(3):272-277.
    • (2000) Genes Dev. , vol.14 , Issue.3 , pp. 272-277
    • Kung, A.L.1    Rebel, V.I.2    Bronson, R.T.3
  • 57
    • 0037069424 scopus 로고    scopus 로고
    • Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal
    • Rebel VI, Kung AL, Tanner EA, et al. Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal. Proc Natl Acad Sci U S A. 2002;99(23):14789-14794.
    • (2002) Proc Natl Acad Sci U S A. , vol.99 , Issue.23 , pp. 14789-14794
    • Rebel, V.I.1    Kung, A.L.2    Tanner, E.A.3
  • 58
    • 79960139808 scopus 로고    scopus 로고
    • Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis
    • Zimmer SN, Zhou Q, Zhou T, et al. Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis. Blood. 2011;118(1):69-79.
    • (2011) Blood. , vol.118 , Issue.1 , pp. 69-79
    • Zimmer, S.N.1    Zhou, Q.2    Zhou, T.3
  • 59
    • 12644314103 scopus 로고    scopus 로고
    • MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16) (q23;p13.3)
    • Sobulo OM, Borrow J, Tomek R, et al. MLL is fused to CBP, a histone acetyltransferase, in therapy-related acute myeloid leukemia with a t(11;16) (q23;p13.3). Proc Natl Acad Sci U S A. 1997;94(16):8732-8737.
    • (1997) Proc Natl Acad Sci U S A. , vol.94 , Issue.16 , pp. 8732-8737
    • Sobulo, O.M.1    Borrow, J.2    Tomek, R.3
  • 60
    • 0034282527 scopus 로고    scopus 로고
    • Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia
    • Lavau C, Du C, Thirman M, et al. Chromatin-related properties of CBP fused to MLL generate a myelodysplastic-like syndrome that evolves into myeloid leukemia. EMBO J. 2000;19(17):4655-4664.
    • (2000) EMBO J. , vol.19 , Issue.17 , pp. 4655-4664
    • Lavau, C.1    Du, C.2    Thirman, M.3
  • 61
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the world health organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937-951.
    • (2009) Blood. , vol.114 , Issue.5 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 62
    • 80052083774 scopus 로고    scopus 로고
    • Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells
    • Lemieux ME, Cheng Z, Zhou Q, et al. Inactivation of a single copy of Crebbp selectively alters pre-mRNA processing in mouse hematopoietic stem cells. PLoS One. 2011;6(8):e24153.
    • (2011) PLoS One. , vol.6 , Issue.8
    • Lemieux, M.E.1    Cheng, Z.2    Zhou, Q.3
  • 63
    • 84862805858 scopus 로고    scopus 로고
    • Mice heterozygous for CREB binding protein are hypersensitive to gamma-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm
    • e5
    • Zimmer SN, Lemieux ME, Karia BP, et al. Mice heterozygous for CREB binding protein are hypersensitive to gamma-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm. Exp Hematol. 2012;40(4):295-306 e5.
    • (2012) Exp Hematol. , vol.40 , Issue.4 , pp. 295-306
    • Zimmer, S.N.1    Lemieux, M.E.2    Karia, B.P.3
  • 64
    • 9144224451 scopus 로고    scopus 로고
    • Processing of primary microRNAs by the Microprocessor complex
    • Denli AM, Tops BB, Plasterk RH, et al. Processing of primary microRNAs by the Microprocessor complex. Nature. 2004;432(7014):231-235.
    • (2004) Nature. , vol.432 , Issue.7014 , pp. 231-235
    • Denli, A.M.1    Tops, B.B.2    Plasterk, R.H.3
  • 65
    • 77955431522 scopus 로고    scopus 로고
    • Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia
    • Kharas MG, Lengner CJ, Al-Shahrour F, et al. Musashi-2 regulates normal hematopoiesis and promotes aggressive myeloid leukemia. Nat Med. 2010;16(8):903-908.
    • (2010) Nat Med. , vol.16 , Issue.8 , pp. 903-908
    • Kharas, M.G.1    Lengner, C.J.2    Al-Shahrour, F.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.