DNMT3A mutational analysis in primary myelofibrosis, chronic myelomonocytic leukemia and advanced phases of myeloproliferative neoplasms

Leukemia

Volumn 25, Issue 7, 2011, Pages 1219-1220

  Abdel Wahab, O ^a   Pardanani, A ^b   Rampal, R ^a   Lasho, T L ^b   Levine, R L ^a   Tefferi, A ^b  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD135 ANTIGEN; DNA; DNA METHYLTRANSFERASE 3A; JANUS KINASE 2; K RAS PROTEIN;

ADULT; ADVANCED CANCER; ARTICLE; CHRONIC MYELOMONOCYTIC LEUKEMIA; DNA SEQUENCE; FEMALE; FOLLOW UP; GENE SEQUENCE; HUMAN; HUMAN TISSUE; MALE; MISSENSE MUTATION; MUTATIONAL ANALYSIS; MYELOID METAPLASIA; MYELOPROLIFERATIVE DISORDER; MYELOPROLIFERATIVE NEOPLASM; NUCLEOTIDE SEQUENCE; ONCOGENE N RAS; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROGNOSIS; SPLENOMEGALY; THROMBOCYTOPENIA;

AGED; COHORT STUDIES; DISEASE PROGRESSION; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA MUTATIONAL ANALYSIS; FEMALE; HETEROZYGOTE; HUMANS; LEUKEMIA, MYELOMONOCYTIC, CHRONIC; MALE; MIDDLE AGED; MYELOPROLIFERATIVE DISORDERS; NEOPLASM PROTEINS; PRIMARY MYELOFIBROSIS; PROGNOSIS;

EID: 79960248721     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2011.82     Document Type: Article

References (5)

1. Yamashita Y, Yuan J, Suetake I, Suzuki H, Ishikawa Y, Choi YL et al. Array-based genomic resequencing of human leukemia. Oncogene 2010; 29: 3723-3731.
2. Ley TJ, Ding L, Walter MJ, McLellan MD, Lamprecht T, Larson DE et al. DNMT3A mutations in acute myeloid leukemia. N Engl J Med 2010; 363: 2424-2433.
3. Walter MJ, Ding L, Shen D, Shao J, Grillot M, McLellan M et al. Recurrent DNMT3A mutations in patients with myelodysplastic syndromes. Leukemia 2011; e-pub ahead of print 18 March 2011.
4. Abdel-Wahab O, Pardanani A, Patel J, Wadleigh M, Lasho T, Heguy A et al. Concomitant analysis of ASXL1 and EZH2 mutations in myelofibrosis, chronic myelomonocytic leukemia, and blast-phase myeloproliferative neoplasms. Leukemia 2011; e-pub ahead of print 01 April 2011.
5. Passamonti F, Cervantes F, Vannucchi AM, Morra E, Rumi E, Pereira A et al. A dynamic prognostic model to predict survival in primary myelofibrosis: a study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment). Blood 2010; 115: 1703-1708.