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Volumn 116, Issue 4, 2015, Pages 700-714

Investigating the transcriptional control of cardiovascular development

Author keywords

Cell differentiation; Heart diseases; Transcription factors; Transcriptional networks; Transcriptional regulatory elements

Indexed keywords

TRANSCRIPTION FACTOR;

EID: 84924138381     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.302832     Document Type: Review
Times cited : (80)

References (139)
  • 1
    • 39749191367 scopus 로고    scopus 로고
    • The developmental genetics of congenital heart disease
    • Bruneau BG. The developmental genetics of congenital heart disease. Nature. 2008;451:943-948. doi: 10.1038/nature06801.
    • (2008) Nature. , vol.451 , pp. 943-948
    • Bruneau, B.G.1
  • 2
    • 84907597199 scopus 로고    scopus 로고
    • Genetic basis of congenital cardiovascular malformations
    • Lalani SR, Belmont JW. Genetic basis of congenital cardiovascular malformations. Eur J Med Genet. 2014;57:402-413. doi: 10.1016/j.ejmg.2014.04.010.
    • (2014) Eur J Med Genet. , vol.57 , pp. 402-413
    • Lalani, S.R.1    Belmont, J.W.2
  • 3
    • 84858770543 scopus 로고    scopus 로고
    • Transcription factor pathways and congenital heart disease
    • McCulley DJ, Black BL. Transcription factor pathways and congenital heart disease. Curr Top Dev Biol. 2012;100:253-277. doi: 10.1016/B978-0-12-387786-4.00008-7.
    • (2012) Curr Top Dev Biol. , vol.100 , pp. 253-277
    • McCulley, D.J.1    Black, B.L.2
  • 4
    • 79551597211 scopus 로고    scopus 로고
    • Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines
    • Kattman SJ, Witty AD, Gagliardi M, Dubois NC, Niapour M, Hotta A, Ellis J, Keller G. Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines. Cell Stem Cell. 2011;8:228-240. doi: 10.1016/j.stem.2010.12.008.
    • (2011) Cell Stem Cell. , vol.8 , pp. 228-240
    • Kattman, S.J.1    Witty, A.D.2    Gagliardi, M.3    Dubois, N.C.4    Niapour, M.5    Hotta, A.6    Ellis, J.7    Keller, G.8
  • 5
    • 84864243791 scopus 로고    scopus 로고
    • Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: A methods overview
    • Mummery CL, Zhang J, Ng ES, Elliott DA, Elefanty AG, Kamp TJ. Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview. Circ Res. 2012;111:344-358. doi: 10.1161/CIRCRESAHA.110.227512.
    • (2012) Circ Res. , vol.111 , pp. 344-358
    • Mummery, C.L.1    Zhang, J.2    Ng, E.S.3    Elliott, D.A.4    Elefanty, A.G.5    Kamp, T.J.6
  • 6
    • 66649127942 scopus 로고    scopus 로고
    • Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors
    • Takeuchi JK, Bruneau BG. Directed transdifferentiation of mouse mesoderm to heart tissue by defined factors. Nature. 2009;459:708-711. doi: 10.1038/nature08039.
    • (2009) Nature. , vol.459 , pp. 708-711
    • Takeuchi, J.K.1    Bruneau, B.G.2
  • 7
    • 59649110883 scopus 로고    scopus 로고
    • Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling
    • Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D. Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009;16:233-244. doi: 10.1016/j.devcel.2008.12.007.
    • (2009) Dev Cell. , vol.16 , pp. 233-244
    • Ieda, M.1    Tsuchihashi, T.2    Ivey, K.N.3    Ross, R.S.4    Hong, T.T.5    Shaw, R.M.6    Srivastava, D.7
  • 12
    • 84877710068 scopus 로고    scopus 로고
    • SnapShot: Transcription regulation: Pausing
    • Fromm G, Gilchrist DA, Adelman K. SnapShot: transcription regulation: pausing. Cell. 2013;153:930-930.e1. doi: 10.1016/j.cell.2013.04.011.
    • (2013) Cell , vol.153 , pp. 930-930.e1
    • Fromm, G.1    Gilchrist, D.A.2    Adelman, K.3
  • 13
    • 84901004299 scopus 로고    scopus 로고
    • The rise of regulatory RNA
    • Morris KV, Mattick JS. The rise of regulatory RNA. Nat Rev Genet. 2014;15:423-437. doi: 10.1038/nrg3722.
    • (2014) Nat Rev Genet. , vol.15 , pp. 423-437
    • Morris, K.V.1    Mattick, J.S.2
  • 14
    • 84877935652 scopus 로고    scopus 로고
    • Transcriptional elongation checkpoint control in development and disease
    • Smith E, Shilatifard A. Transcriptional elongation checkpoint control in development and disease. Genes Dev. 2013;27:1079-1088. doi: 10.1101/gad.215137.113.
    • (2013) Genes Dev. , vol.27 , pp. 1079-1088
    • Smith, E.1    Shilatifard, A.2
  • 15
    • 0025201511 scopus 로고
    • A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila
    • Bodmer R, Jan LY, Jan YN. A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila. Development. 1990;110:661-669.
    • (1990) Development. , vol.110 , pp. 661-669
    • Bodmer, R.1    Jan, L.Y.2    Jan, Y.N.3
  • 16
    • 0027282774 scopus 로고
    • The gene tinman is required for specification of the heart and visceral muscles in Drosophila
    • Bodmer R. The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development. 1993;118:719-729.
    • (1993) Development. , vol.118 , pp. 719-729
    • Bodmer, R.1
  • 17
    • 0027237596 scopus 로고
    • Tinman and bagpipe: Two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila
    • Azpiazu N, Frasch M. tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev. 1993;7:1325-1340.
    • (1993) Genes Dev. , vol.7 , pp. 1325-1340
    • Azpiazu, N.1    Frasch, M.2
  • 18
    • 0027383023 scopus 로고
    • Nkx-2.5: A novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants
    • Lints TJ, Parsons LM, Hartley L, Lyons I, Harvey RP. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development. 1993;119:419-431.
    • (1993) Development. , vol.119 , pp. 419-431
    • Lints, T.J.1    Parsons, L.M.2    Hartley, L.3    Lyons, I.4    Harvey, R.P.5
  • 19
    • 0029549692 scopus 로고
    • A subclass of bHLH proteins required for cardiac morphogenesis
    • Srivastava D, Cserjesi P, Olson EN. A subclass of bHLH proteins required for cardiac morphogenesis. Science. 1995;270:1995-1999.
    • (1995) Science. , vol.270 , pp. 1995-1999
    • Srivastava, D.1    Cserjesi, P.2    Olson, E.N.3
  • 20
    • 0031685432 scopus 로고    scopus 로고
    • Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice
    • Ranganayakulu G, Elliott DA, Harvey RP, Olson EN. Divergent roles for NK-2 class homeobox genes in cardiogenesis in flies and mice. Development. 1998;125:3037-3048.
    • (1998) Development. , vol.125 , pp. 3037-3048
    • Ranganayakulu, G.1    Elliott, D.A.2    Harvey, R.P.3    Olson, E.N.4
  • 21
  • 24
    • 77954222814 scopus 로고    scopus 로고
    • Chromatin regulation by Brg1 underlies heart muscle development and disease
    • Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP. Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature. 2010;466:62-67. doi: 10.1038/nature09130.
    • (2010) Nature. , vol.466 , pp. 62-67
    • Hang, C.T.1    Yang, J.2    Han, P.3    Cheng, H.L.4    Shang, C.5    Ashley, E.6    Zhou, B.7    Chang, C.P.8
  • 26
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • Iso T, Kedes L, Hamamori Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J Cell Physiol. 2003;194:237-255. doi: 10.1002/jcp.10208.
    • (2003) J Cell Physiol. , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 27
    • 19944426358 scopus 로고    scopus 로고
    • ENU induced mutations causing congenital cardiovascular anomalies
    • Yu Q. ENU induced mutations causing congenital cardiovascular anomalies. Development. 2004;131:6211-6223.
    • (2004) Development. , vol.131 , pp. 6211-6223
    • Yu, Q.1
  • 28
    • 80052511434 scopus 로고    scopus 로고
    • The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation
    • Costello I, Pimeisl IM, Dräger S, Bikoff EK, Robertson EJ, Arnold SJ. The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation. Nat Cell Biol. 2011;13:1084-1091. doi: 10.1038/ncb2304.
    • (2011) Nat Cell Biol. , vol.13 , pp. 1084-1091
    • Costello, I.1    Pimeisl, I.M.2    Dräger, S.3    Bikoff, E.K.4    Robertson, E.J.5    Arnold, S.J.6
  • 30
    • 1842413728 scopus 로고    scopus 로고
    • Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family
    • Li QY, Newbury-Ecob RA, Terrett JA, et al. Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family. Nat Genet. 1997;15:21-29. doi: 10.1038/ng0197-21.
    • (1997) Nat Genet. , vol.15 , pp. 21-29
    • Li, Q.Y.1    Newbury-Ecob, R.A.2    Terrett, J.A.3
  • 32
    • 0033168070 scopus 로고    scopus 로고
    • Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome
    • Bruneau BG, Logan M, Davis N, Levi T, Tabin CJ, Seidman JG, Seidman CE. Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome. Dev Biol. 1999;211:100-108. doi: 10.1006/dbio.1999.9298.
    • (1999) Dev Biol. , vol.211 , pp. 100-108
    • Bruneau, B.G.1    Logan, M.2    Davis, N.3    Levi, T.4    Tabin, C.J.5    Seidman, J.G.6    Seidman, C.E.7
  • 33
    • 84879001958 scopus 로고    scopus 로고
    • De novo mutations in histone-modifying genes in congenital heart disease
    • Zaidi S, Choi M, Wakimoto H, et al. De novo mutations in histone-modifying genes in congenital heart disease. Nature. 2013;498:220-223. doi: 10.1038/nature12141.
    • (2013) Nature. , vol.498 , pp. 220-223
    • Zaidi, S.1    Choi, M.2    Wakimoto, H.3
  • 34
    • 77956642100 scopus 로고    scopus 로고
    • Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome
    • Ng SB, Bigham AW, Buckingham KJ, et al. Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome. Nat Genet. 2010;42:790-793. doi: 10.1038/ng.646.
    • (2010) Nat Genet. , vol.42 , pp. 790-793
    • Ng, S.B.1    Bigham, A.W.2    Buckingham, K.J.3
  • 35
    • 69949094996 scopus 로고    scopus 로고
    • Reptilian heart development and the molecular basis of cardiac chamber evolution
    • Koshiba-Takeuchi K, Mori AD, Kaynak BL, et al. Reptilian heart development and the molecular basis of cardiac chamber evolution. Nature. 2009;461:95-98. doi: 10.1038/nature08324.
    • (2009) Nature. , vol.461 , pp. 95-98
    • Koshiba-Takeuchi, K.1    Mori, A.D.2    Kaynak, B.L.3
  • 37
    • 84856707310 scopus 로고    scopus 로고
    • Polycomb repressive complex 2 regulates normal development of the mouse heart
    • He A, Ma Q, Cao J, Gise von A, et al. Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012;110:406-415.
    • (2012) Circ Res. , vol.110 , pp. 406-415
    • He, A.1    Ma, Q.2    Cao, J.3    Gise Von, A.4
  • 40
    • 0034931034 scopus 로고    scopus 로고
    • Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation
    • Hiroi Y, Kudoh S, Monzen K, Ikeda Y, Yazaki Y, Nagai R, Komuro I. Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation. Nat Genet. 2001;28:276-280. doi: 10.1038/90123.
    • (2001) Nat Genet. , vol.28 , pp. 276-280
    • Hiroi, Y.1    Kudoh, S.2    Monzen, K.3    Ikeda, Y.4    Yazaki, Y.5    Nagai, R.6    Komuro, I.7
  • 41
    • 0031472234 scopus 로고    scopus 로고
    • FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation
    • Tsang AP, Visvader JE, Turner CA, Fujiwara Y, Yu C, Weiss MJ, Crossley M, Orkin SH. FOG, a multitype zinc finger protein, acts as a cofactor for transcription factor GATA-1 in erythroid and megakaryocytic differentiation. Cell. 1997;90:109-119.
    • (1997) Cell. , vol.90 , pp. 109-119
    • Tsang, A.P.1    Visvader, J.E.2    Turner, C.A.3    Fujiwara, Y.4    Yu, C.5    Weiss, M.J.6    Crossley, M.7    Orkin, S.H.8
  • 42
    • 0035312839 scopus 로고    scopus 로고
    • Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors
    • Crispino JD. Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors. Genes Dev. 2001;15:839-844.
    • (2001) Genes Dev. , vol.15 , pp. 839-844
    • Crispino, J.D.1
  • 43
    • 84904764792 scopus 로고    scopus 로고
    • The emergence of proteome-wide technologies: Systematic analysis of proteins comes of age
    • Breker M, Schuldiner M. The emergence of proteome-wide technologies: systematic analysis of proteins comes of age. Nat Rev Mol Cell Biol. 2014;15:453-464. doi: 10.1038/nrm3821.
    • (2014) Nat Rev Mol Cell Biol. , vol.15 , pp. 453-464
    • Breker, M.1    Schuldiner, M.2
  • 45
    • 84879613791 scopus 로고    scopus 로고
    • Villén J. Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation
    • Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods. 2013;10:676-682. doi: 10.1038/nmeth.2519.
    • (2013) Nat Methods. , vol.10 , pp. 676-682
    • Swaney, D.L.1    Beltrao, P.2    Starita, L.3    Guo, A.4    Rush, J.5    Fields, S.6    Krogan, N.J.7
  • 47
    • 0035445835 scopus 로고    scopus 로고
    • Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
    • Ghosh TK, Packham EA, Bonser AJ, Robinson TE, Cross SJ, Brook JD. Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome. Hum Mol Genet. 2001;10:1983-1994.
    • (2001) Hum Mol Genet. , vol.10 , pp. 1983-1994
    • Ghosh, T.K.1    Packham, E.A.2    Bonser, A.J.3    Robinson, T.E.4    Cross, S.J.5    Brook, J.D.6
  • 48
    • 79955036679 scopus 로고    scopus 로고
    • Experimental strategies for studying transcription factor-DNA binding specificities
    • Geertz M, Maerkl SJ. Experimental strategies for studying transcription factor-DNA binding specificities. Brief Funct Genomics. 2011;9:362-373.
    • (2011) Brief Funct Genomics. , vol.9 , pp. 362-373
    • Geertz, M.1    Maerkl, S.J.2
  • 49
    • 84865353203 scopus 로고    scopus 로고
    • Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression
    • Chlon TM, Doré LC, Crispino JD. Cofactor-mediated restriction of GATA-1 chromatin occupancy coordinates lineage-specific gene expression. Mol Cell. 2012;47:608-621. doi: 10.1016/j.molcel.2012.05.051.
    • (2012) Mol Cell. , vol.47 , pp. 608-621
    • Chlon, T.M.1    Doré, L.C.2    Crispino, J.D.3
  • 50
    • 83255164884 scopus 로고    scopus 로고
    • Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution
    • Rhee HS, Pugh BF. Comprehensive genome-wide protein-DNA interactions detected at single-nucleotide resolution. Cell. 2011;147:1408-1419. doi: 10.1016/j.cell.2011.11.013.
    • (2011) Cell. , vol.147 , pp. 1408-1419
    • Rhee, H.S.1    Pugh, B.F.2
  • 51
    • 84901921616 scopus 로고    scopus 로고
    • Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers
    • Barozzi I, Simonatto M, Bonifacio S, Yang L, Rohs R, Ghisletti S, Natoli G. Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers. Mol Cell. 2014;54:844-857. doi: 10.1016/j.molcel.2014.04.006.
    • (2014) Mol Cell. , vol.54 , pp. 844-857
    • Barozzi, I.1    Simonatto, M.2    Bonifacio, S.3    Yang, L.4    Rohs, R.5    Ghisletti, S.6    Natoli, G.7
  • 52
    • 84887072795 scopus 로고    scopus 로고
    • Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants
    • Parker SCJ, Stitzel ML, Taylor DL, et al. Chromatin stretch enhancer states drive cell-specific gene regulation and harbor human disease risk variants. Proc Natl Acad Sci. 2013;110:17921-17926.
    • (2013) Proc Natl Acad Sci. , vol.110 , pp. 17921-17926
    • Parker, S.C.J.1    Stitzel, M.L.2    Taylor, D.L.3
  • 54
    • 79955027617 scopus 로고    scopus 로고
    • Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart
    • He A, Kong SW, Ma Q, Pu WT. Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. Proc Natl Acad Sci U S A. 2011;108:5632-5637. doi: 10.1073/pnas.1016959108.
    • (2011) Proc Natl Acad Sci u S A. , vol.108 , pp. 5632-5637
    • He, A.1    Kong, S.W.2    Ma, Q.3    Pu, W.T.4
  • 57
    • 84865249952 scopus 로고    scopus 로고
    • Transcription factors: From enhancer binding to developmental control
    • Spitz F, Furlong EE. Transcription factors: from enhancer binding to developmental control. Nat Rev Genet. 2012;13:613-626. doi: 10.1038/nrg3207.
    • (2012) Nat Rev Genet. , vol.13 , pp. 613-626
    • Spitz, F.1    Furlong, E.E.2
  • 58
    • 84872540994 scopus 로고    scopus 로고
    • DNA-binding specificities of human transcription factors
    • Jolma A, Yan J, Whitington T, et al. DNA-binding specificities of human transcription factors. Cell. 2013;152:327-339.
    • (2013) Cell. , vol.152 , pp. 327-339
    • Jolma, A.1    Yan, J.2    Whitington, T.3
  • 60
    • 84902810053 scopus 로고    scopus 로고
    • In pursuit of design principles of regulatory sequences
    • Levo M, Segal E. In pursuit of design principles of regulatory sequences. Nat Rev Genet. 2014;15:453-468. doi: 10.1038/nrg3684.
    • (2014) Nat Rev Genet. , vol.15 , pp. 453-468
    • Levo, M.1    Segal, E.2
  • 62
    • 84865755978 scopus 로고    scopus 로고
    • The accessible chromatin landscape of the human genome
    • Thurman RE, Rynes E, Humbert R, et al. The accessible chromatin landscape of the human genome. Nature. 2012;489:75-82. doi: 10.1038/nature11232.
    • (2012) Nature. , vol.489 , pp. 75-82
    • Thurman, R.E.1    Rynes, E.2    Humbert, R.3
  • 64
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • ENCODE Project Consortium, Consortium TEP. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489:57-74.
    • (2012) Nature. , vol.489 , pp. 57-74
    • ENCODE Project Consortium1    Consortium TEP2
  • 66
    • 84897459814 scopus 로고    scopus 로고
    • FANTOM Consortium. An atlas of active enhancers across human cell types and tissues
    • Andersson R, Gebhard C, Miguel-Escalada I, et al FANTOM Consortium. An atlas of active enhancers across human cell types and tissues. Nature. 2014;507:455-461. doi: 10.1038/nature12787.
    • (2014) Nature. , vol.507 , pp. 455-461
    • Andersson, R.1    Gebhard, C.2    Miguel-Escalada, I.3
  • 67
    • 84861529303 scopus 로고    scopus 로고
    • Enhancers as information integration hubs in development: Lessons from genomics
    • Buecker C, Wysocka J. Enhancers as information integration hubs in development: lessons from genomics. Trends Genet. 2012;28:276-284. doi: 10.1016/j.tig.2012.02.008.
    • (2012) Trends Genet. , vol.28 , pp. 276-284
    • Buecker, C.1    Wysocka, J.2
  • 70
    • 84888877924 scopus 로고    scopus 로고
    • Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
    • Buenrostro JD, Giresi PG, Zaba LC, Chang HY, Greenleaf WJ. Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. Nat Methods. 2013;10:1213-1218. doi: 10.1038/nmeth.2688.
    • (2013) Nat Methods. , vol.10 , pp. 1213-1218
    • Buenrostro, J.D.1    Giresi, P.G.2    Zaba, L.C.3    Chang, H.Y.4    Greenleaf, W.J.5
  • 71
    • 84880512956 scopus 로고    scopus 로고
    • ETS Factors Regulate Vegf-Dependent Arterial Specification
    • Wythe JD, Dang LTH, Devine WP, et al. ETS Factors Regulate Vegf-Dependent Arterial Specification. Dev Cell. 2013;26:45-58.
    • (2013) Dev Cell. , vol.26 , pp. 45-58
    • Wythe, J.D.1    Dang, L.T.H.2    Devine, W.P.3
  • 73
    • 77956641239 scopus 로고    scopus 로고
    • ChIP-Seq identification of weakly conserved heart enhancers
    • Blow MJ, McCulley DJ, Li Z, et al. ChIP-Seq identification of weakly conserved heart enhancers. Nat Genet. 2010;42:806-810. doi: 10.1038/ng.650.
    • (2010) Nat Genet. , vol.42 , pp. 806-810
    • Blow, M.J.1    McCulley, D.J.2    Li, Z.3
  • 75
    • 33751316959 scopus 로고    scopus 로고
    • In vivo enhancer analysis of human conserved non-coding sequences
    • Pennacchio LA, Ahituv N, Moses AM, et al. In vivo enhancer analysis of human conserved non-coding sequences. Nature. 2006;444:499-502. doi: 10.1038/nature05295.
    • (2006) Nature. , vol.444 , pp. 499-502
    • Pennacchio, L.A.1    Ahituv, N.2    Moses, A.M.3
  • 78
    • 84867073340 scopus 로고    scopus 로고
    • Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage
    • Wamstad JA, Alexander JM, Truty RM, et al. Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell. 2012;151:206-220. doi: 10.1016/j.cell.2012.07.035.
    • (2012) Cell. , vol.151 , pp. 206-220
    • Wamstad, J.A.1    Alexander, J.M.2    Truty, R.M.3
  • 79
    • 84655164920 scopus 로고    scopus 로고
    • Large-scale discovery of enhancers from human heart tissue
    • May D, Blow MJ, Kaplan T, et al. Large-scale discovery of enhancers from human heart tissue. Nat Genet. 2012;44:89-93. doi: 10.1038/ng.1006.
    • (2012) Nat Genet. , vol.44 , pp. 89-93
    • May, D.1    Blow, M.J.2    Kaplan, T.3
  • 81
    • 77649086970 scopus 로고    scopus 로고
    • A map of open chromatin in human pancreatic islets
    • Gaulton KJ, Nammo T, Pasquali L, et al. A map of open chromatin in human pancreatic islets. Nat Genet. 2010;42:255-259.
    • (2010) Nat Genet. , vol.42 , pp. 255-259
    • Gaulton, K.J.1    Nammo, T.2    Pasquali, L.3
  • 83
    • 0025741345 scopus 로고
    • Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression
    • Knowlton KU, Baracchini E, Ross RS, Harris AN, Henderson SA, Evans SM, Glembotski CC, Chien KR. Co-regulation of the atrial natriuretic factor and cardiac myosin light chain-2 genes during alpha-adrenergic stimulation of neonatal rat ventricular cells. Identification of cis sequences within an embryonic and a constitutive contractile protein gene which mediate inducible expression. J Biol Chem. 1991;266:7759-7768.
    • (1991) J Biol Chem. , vol.266 , pp. 7759-7768
    • Knowlton, K.U.1    Baracchini, E.2    Ross, R.S.3    Harris, A.N.4    Henderson, S.A.5    Evans, S.M.6    Glembotski, C.C.7    Chien, K.R.8
  • 84
    • 0028871928 scopus 로고
    • Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like element
    • Sprenkle AB, Murray SF, Glembotski CC. Involvement of multiple cis elements in basal- and alpha-adrenergic agonist-inducible atrial natriuretic factor transcription. Roles for serum response elements and an SP-1-like element. Circ Res. 1995;77:1060-1069.
    • (1995) Circ Res. , vol.77 , pp. 1060-1069
    • Sprenkle, A.B.1    Murray, S.F.2    Glembotski, C.C.3
  • 85
    • 84874381107 scopus 로고    scopus 로고
    • Genomewide quantitative enhancer activity maps identified by STARR-seq
    • Arnold CD, Gerlach D, Stelzer C, Boryñ £M, Rath M, Stark A. Genomewide quantitative enhancer activity maps identified by STARR-seq. Science. 2013;339:1074-1077. doi: 10.1126/science.1232542.
    • (2013) Science. , vol.339 , pp. 1074-1077
    • Arnold, C.D.1    Gerlach, D.2    Stelzer, C.3    Boryñ, Ł.4    Rath, M.5    Stark, A.6
  • 86
    • 0032727374 scopus 로고    scopus 로고
    • Building the heart piece by piece: Modularity of cis-elements regulating Nkx2-5 transcription
    • Schwartz RJ, Olson EN. Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription. Development. 1999;126:4187-4192.
    • (1999) Development. , vol.126 , pp. 4187-4192
    • Schwartz, R.J.1    Olson, E.N.2
  • 88
    • 42049095509 scopus 로고    scopus 로고
    • Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences
    • Horsthuis T, Houweling AC, Habets PE, de Lange FJ, el Azzouzi H, Clout DE, Moorman AF, Christoffels VM. Distinct regulation of developmental and heart disease-induced atrial natriuretic factor expression by two separate distal sequences. Circ Res. 2008;102:849-859. doi: 10.1161/CIRCRESAHA.107.170571.
    • (2008) Circ Res. , vol.102 , pp. 849-859
    • Horsthuis, T.1    Houweling, A.C.2    Habets, P.E.3    De Lange, F.J.4    El Azzouzi, H.5    Clout, D.E.6    Moorman, A.F.7    Christoffels, V.M.8
  • 90
    • 0032937224 scopus 로고    scopus 로고
    • Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer
    • Lien CL, Wu C, Mercer B, Webb R, Richardson JA, Olson EN. Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development. 1999;126:75-84.
    • (1999) Development. , vol.126 , pp. 75-84
    • Lien, C.L.1    Wu, C.2    Mercer, B.3    Webb, R.4    Richardson, J.A.5    Olson, E.N.6
  • 91
    • 84901834984 scopus 로고    scopus 로고
    • The architecture of gene expression: Integrating dispersed cis-regulatory modules into coherent regulatory domains
    • Schwarzer W, Spitz F. The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains. Curr Opin Genet Dev. 2014;27:74-82. doi: 10.1016/j.gde.2014.03.014.
    • (2014) Curr Opin Genet Dev. , vol.27 , pp. 74-82
    • Schwarzer, W.1    Spitz, F.2
  • 92
    • 79953176250 scopus 로고    scopus 로고
    • Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor
    • Ruf S, Symmons O, Uslu VV, Dolle D, Hot C, Ettwiller L, Spitz F. Large-scale analysis of the regulatory architecture of the mouse genome with a transposon-associated sensor. Nat Genet. 2011;43:379-386. doi: 10.1038/ng.790.
    • (2011) Nat Genet. , vol.43 , pp. 379-386
    • Ruf, S.1    Symmons, O.2    Uslu, V.V.3    Dolle, D.4    Hot, C.5    Ettwiller, L.6    Spitz, F.7
  • 95
    • 0037349438 scopus 로고    scopus 로고
    • Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development
    • Yanagisawa H, Clouthier DE, Richardson JA, Charité J, Olson EN. Targeted deletion of a branchial arch-specific enhancer reveals a role of dHAND in craniofacial development. Development. 2003;130:1069-1078.
    • (2003) Development. , vol.130 , pp. 1069-1078
    • Yanagisawa, H.1    Clouthier, D.E.2    Richardson, J.A.3    Charité, J.4    Olson, E.N.5
  • 96
    • 84886257610 scopus 로고    scopus 로고
    • Fine tuning of craniofacial morphology by distant-acting enhancers
    • Attanasio C, Nord AS, Zhu Y, et al. Fine tuning of craniofacial morphology by distant-acting enhancers. Science. 2013;342:1241006. doi: 10.1126/science.1241006.
    • (2013) Science. , vol.342 , pp. 1241006
    • Attanasio, C.1    Nord, A.S.2    Zhu, Y.3
  • 97
    • 84855804140 scopus 로고    scopus 로고
    • Shadow enhancers: Frequently asked questions about distributed cis-regulatory information and enhancer redundancy
    • Barolo S. Shadow enhancers: frequently asked questions about distributed cis-regulatory information and enhancer redundancy. Bioessays. 2012;34:135-141. doi: 10.1002/bies.201100121.
    • (2012) Bioessays. , vol.34 , pp. 135-141
    • Barolo, S.1
  • 98
    • 77958111633 scopus 로고    scopus 로고
    • The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
    • Malik S, Roeder RG. The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation. Nat Rev Genet. 2010;11:761-772. doi: 10.1038/nrg2901.
    • (2010) Nat Rev Genet. , vol.11 , pp. 761-772
    • Malik, S.1    Roeder, R.G.2
  • 100
    • 83755195189 scopus 로고    scopus 로고
    • Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
    • Krebs P, Fan W, Chen YH, et al. Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet. Proc Natl Acad Sci U S A. 2011;108:19678-19682. doi: 10.1073/pnas.1117835108.
    • (2011) Proc Natl Acad Sci u S A. , vol.108 , pp. 19678-19682
    • Krebs, P.1    Fan, W.2    Chen, Y.H.3
  • 101
    • 0029617947 scopus 로고
    • Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome
    • Thanos D, Maniatis T. Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell. 1995;83:1091-1100.
    • (1995) Cell. , vol.83 , pp. 1091-1100
    • Thanos, D.1    Maniatis, T.2
  • 102
    • 17644397256 scopus 로고    scopus 로고
    • Transcriptional enhancers: Intelligent enhanceosomes or flexible billboards?
    • Arnosti DN, Kulkarni MM. Transcriptional enhancers: intelligent enhanceosomes or flexible billboards? J Cell Biochem. 2005;94:890-898. doi: 10.1002/jcb.20352.
    • (2005) J Cell Biochem. , vol.94 , pp. 890-898
    • Arnosti, D.N.1    Kulkarni, M.M.2
  • 103
    • 84856704764 scopus 로고    scopus 로고
    • A transcription factor collective defines cardiac cell fate and reflects lineage history
    • Junion G, Spivakov M, Girardot C, Braun M, Gustafson EH, Birney E, Furlong EE. A transcription factor collective defines cardiac cell fate and reflects lineage history. Cell. 2012;148:473-486. doi: 10.1016/j. cell.2012.01.030.
    • (2012) Cell. , vol.148 , pp. 473-486
    • Junion, G.1    Spivakov, M.2    Girardot, C.3    Braun, M.4    Gustafson, E.H.5    Birney, E.6    Furlong, E.E.7
  • 105
    • 75949115944 scopus 로고    scopus 로고
    • Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs
    • Giorgetti L, Siggers T, Tiana G, Caprara G, Notarbartolo S, Corona T, Pasparakis M, Milani P, Bulyk ML, Natoli G. Noncooperative interactions between transcription factors and clustered DNA binding sites enable graded transcriptional responses to environmental inputs. Mol Cell. 2010;37:418-428. doi: 10.1016/j.molcel.2010.01.016.
    • (2010) Mol Cell. , vol.37 , pp. 418-428
    • Giorgetti, L.1    Siggers, T.2    Tiana, G.3    Caprara, G.4    Notarbartolo, S.5    Corona, T.6    Pasparakis, M.7    Milani, P.8    Bulyk, M.L.9    Natoli, G.10
  • 106
    • 0032479079 scopus 로고    scopus 로고
    • Going the distance: A current view of enhancer action
    • Blackwood EM, Kadonaga JT. Going the distance: a current view of enhancer action. Science. 1998;281:60-63.
    • (1998) Science. , vol.281 , pp. 60-63
    • Blackwood, E.M.1    Kadonaga, J.T.2
  • 109
    • 84855297335 scopus 로고    scopus 로고
    • A decade of 3C technologies: Insights into nuclear organization
    • de Wit E, de Laat W. A decade of 3C technologies: insights into nuclear organization. Genes Dev. 2012;26:11-24. doi: 10.1101/gad.179804.111.
    • (2012) Genes Dev. , vol.26 , pp. 11-24
    • De Wit, E.1    De Laat, W.2
  • 110
    • 84897568607 scopus 로고    scopus 로고
    • A common genetic variant within SCN10A modulates cardiac SCN5A expression
    • van den Boogaard M, Smemo S, Burnicka-Turek O, et al. A common genetic variant within SCN10A modulates cardiac SCN5A expression. J Clin Invest. 2014;124:1844-1852. doi: 10.1172/JCI73140.
    • (2014) J Clin Invest. , vol.124 , pp. 1844-1852
    • Van Den Boogaard, M.1    Smemo, S.2    Burnicka-Turek, O.3
  • 111
    • 84881613036 scopus 로고    scopus 로고
    • Segmental folding of chromosomes: A basis for structural and regulatory chromosomal neighborhoods?
    • Nora EP, Dekker J, Heard E. Segmental folding of chromosomes: a basis for structural and regulatory chromosomal neighborhoods? Bioessays. 2013;35:818-828. doi: 10.1002/bies.201300040.
    • (2013) Bioessays. , vol.35 , pp. 818-828
    • Nora, E.P.1    Dekker, J.2    Heard, E.3
  • 112
    • 84861100147 scopus 로고    scopus 로고
    • Spatial partitioning of the regulatory landscape of the X-inactivation centre
    • Nora EP, Lajoie BR, Schulz EG, et al. Spatial partitioning of the regulatory landscape of the X-inactivation centre. Nature. 2012;485:381-385.
    • (2012) Nature. , vol.485 , pp. 381-385
    • Nora, E.P.1    Lajoie, B.R.2    Schulz, E.G.3
  • 114
    • 0028217599 scopus 로고
    • Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype
    • Evans SM, Tai LJ, Tan VP, Newton CB, Chien KR. Heterokaryons of cardiac myocytes and fibroblasts reveal the lack of dominance of the cardiac muscle phenotype. Mol Cell Biol. 1994;14:4269-4279.
    • (1994) Mol Cell Biol. , vol.14 , pp. 4269-4279
    • Evans, S.M.1    Tai, L.J.2    Tan, V.P.3    Newton, C.B.4    Chien, K.R.5
  • 115
    • 84883765490 scopus 로고    scopus 로고
    • Chromatin modulators as facilitating factors in cellular reprogramming
    • Luna-Zurita L, Bruneau BG. Chromatin modulators as facilitating factors in cellular reprogramming. Curr Opin Genet Dev. 2013;23:556-561. doi: 10.1016/j.gde.2013.07.002.
    • (2013) Curr Opin Genet Dev. , vol.23 , pp. 556-561
    • Luna-Zurita, L.1    Bruneau, B.G.2
  • 116
    • 84896414509 scopus 로고    scopus 로고
    • Chromatin looping and organization at developmentally regulated gene loci
    • Noordermeer D, Duboule D. Chromatin looping and organization at developmentally regulated gene loci. Wiley Interdiscip Rev Dev Biol. 2013;2:615-630. doi: 10.1002/wdev.103.
    • (2013) Wiley Interdiscip Rev Dev Biol. , vol.2 , pp. 615-630
    • Noordermeer, D.1    Duboule, D.2
  • 117
    • 84857054810 scopus 로고    scopus 로고
    • Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification
    • Dillon N. Factor mediated gene priming in pluripotent stem cells sets the stage for lineage specification. Bioessays. 2012;34:194-204. doi: 10.1002/bies.201100137.
    • (2012) Bioessays. , vol.34 , pp. 194-204
    • Dillon, N.1
  • 118
    • 78650010371 scopus 로고    scopus 로고
    • The "occlusis" model of cell fate restriction
    • Lahn BT. The "occlusis" model of cell fate restriction. Bioessays. 2011;33:13-20. doi: 10.1002/bies.201000090.
    • (2011) Bioessays. , vol.33 , pp. 13-20
    • Lahn, B.T.1
  • 119
    • 84884626274 scopus 로고    scopus 로고
    • Chromatin sampling-an emerging perspective on targeting polycomb repressor proteins
    • Klose RJ, Cooper S, Farcas AM, Blackledge NP, Brockdorff N. Chromatin sampling-an emerging perspective on targeting polycomb repressor proteins. PLoS Genet. 2013;9:e1003717. doi: 10.1371/journal.pgen.1003717.
    • (2013) PLoS Genet. , vol.9 , pp. e1003717
    • Klose, R.J.1    Cooper, S.2    Farcas, A.M.3    Blackledge, N.P.4    Brockdorff, N.5
  • 120
    • 77956648493 scopus 로고    scopus 로고
    • Pioneer factors in embryonic stem cells and differentiation
    • Smale ST. Pioneer factors in embryonic stem cells and differentiation. Curr Opin Genet Dev. 2010;20:519-526. doi: 10.1016/j.gde.2010.06.010.
    • (2010) Curr Opin Genet Dev. , vol.20 , pp. 519-526
    • Smale, S.T.1
  • 121
    • 84871590663 scopus 로고    scopus 로고
    • BAF60 A, B, and Cs of muscle determination and renewal
    • Puri PL, Mercola M. BAF60 A, B, and Cs of muscle determination and renewal. Genes Dev. 2012;26:2673-2683. doi: 10.1101/gad.207415.112.
    • (2012) Genes Dev. , vol.26 , pp. 2673-2683
    • Puri, P.L.1    Mercola, M.2
  • 122
    • 84880317634 scopus 로고    scopus 로고
    • Chromatin remodelling complex dosage modulates transcription factor function in heart development
    • Takeuchi JK, Lou X, Alexander JM, et al. Chromatin remodelling complex dosage modulates transcription factor function in heart development. Nat Commun. 2011;2:187. doi: 10.1038/ncomms1187.
    • (2011) Nat Commun. , vol.2 , pp. 187
    • Takeuchi, J.K.1    Lou, X.2    Alexander, J.M.3
  • 123
    • 77956604362 scopus 로고    scopus 로고
    • Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation
    • Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA. Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010;19:450-459. doi: 10.1016/j.devcel.2010.08.012.
    • (2010) Dev Cell. , vol.19 , pp. 450-459
    • Trivedi, C.M.1    Zhu, W.2    Wang, Q.3    Jia, C.4    Kee, H.J.5    Li, L.6    Hannenhalli, S.7    Epstein, J.A.8
  • 124
    • 0034635987 scopus 로고    scopus 로고
    • Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases
    • Lu J, McKinsey TA, Nicol RL, Olson EN. Signal-dependent activation of the MEF2 transcription factor by dissociation from histone deacetylases. Proc Natl Acad Sci U S A. 2000;97:4070-4075. doi: 10.1073/pnas.080064097.
    • (2000) Proc Natl Acad Sci u S A. , vol.97 , pp. 4070-4075
    • Lu, J.1    McKinsey, T.A.2    Nicol, R.L.3    Olson, E.N.4
  • 125
    • 84868202020 scopus 로고    scopus 로고
    • Epigenetic obstacles encountered by transcription factors: Reprogramming against all odds
    • Gifford CA, Meissner A. Epigenetic obstacles encountered by transcription factors: reprogramming against all odds. Curr Opin Genet Dev. 2012;22:409-415. doi: 10.1016/j.gde.2012.08.002.
    • (2012) Curr Opin Genet Dev. , vol.22 , pp. 409-415
    • Gifford, C.A.1    Meissner, A.2
  • 126
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • Ieda M, Fu JD, Delgado-Olguin P, Vedantham V, Hayashi Y, Bruneau BG, Srivastava D. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell. 2010;142:375-386. doi: 10.1016/j.cell.2010.07.002.
    • (2010) Cell. , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3    Vedantham, V.4    Hayashi, Y.5    Bruneau, B.G.6    Srivastava, D.7
  • 127
    • 34249079154 scopus 로고    scopus 로고
    • Network motifs: Theory and experimental approaches
    • Alon U. Network motifs: theory and experimental approaches. Nat Rev Genet. 2007;8:450-461. doi: 10.1038/nrg2102.
    • (2007) Nat Rev Genet. , vol.8 , pp. 450-461
    • Alon, U.1
  • 128
    • 33847344204 scopus 로고    scopus 로고
    • An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation
    • Prall OW, Menon MK, Solloway MJ, et al. An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell. 2007;128:947-959. doi: 10.1016/j.cell.2007.01.042.
    • (2007) Cell. , vol.128 , pp. 947-959
    • Prall, O.W.1    Menon, M.K.2    Solloway, M.J.3
  • 129
    • 70449132583 scopus 로고    scopus 로고
    • Combinatorial binding predicts spatio-temporal cis-regulatory activity
    • Zinzen RP, Girardot C, Gagneur J, Braun M, Furlong EEM. Combinatorial binding predicts spatio-temporal cis-regulatory activity. Nature. 2009;461:65-70.
    • (2009) Nature. , vol.461 , pp. 65-70
    • Zinzen, R.P.1    Girardot, C.2    Gagneur, J.3    Braun, M.4    Furlong, E.E.M.5
  • 130
    • 84902096048 scopus 로고    scopus 로고
    • Development and applications of CRISPR-Cas9 for genome engineering
    • Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell. 2014;157:1262-1278. doi: 10.1016/j.cell.2014.05.010.
    • (2014) Cell. , vol.157 , pp. 1262-1278
    • Hsu, P.D.1    Lander, E.S.2    Zhang, F.3
  • 131
    • 84865082563 scopus 로고    scopus 로고
    • Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation
    • Xie L, Hoffmann AD, Burnicka-Turek O, Friedland-Little JM, Zhang K, Moskowitz IP. Tbx5-hedgehog molecular networks are essential in the second heart field for atrial septation. Dev Cell. 2012;23:280-291. doi: 10.1016/j.devcel.2012.06.006.
    • (2012) Dev Cell. , vol.23 , pp. 280-291
    • Xie, L.1    Hoffmann, A.D.2    Burnicka-Turek, O.3    Friedland-Little, J.M.4    Zhang, K.5    Moskowitz, I.P.6
  • 135
    • 77953466536 scopus 로고    scopus 로고
    • Nuclear reprogramming to a pluripotent state by three approaches
    • Yamanaka S, Blau HM. Nuclear reprogramming to a pluripotent state by three approaches. Nature. 2010;465:704-712. doi: 10.1038/nature09229.
    • (2010) Nature. , vol.465 , pp. 704-712
    • Yamanaka, S.1    Blau, H.M.2
  • 136
    • 84879687374 scopus 로고    scopus 로고
    • Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16
    • Cordell HJ, Bentham J, Topf A, et al. Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16. Nat Genet. 2013;45:822-824. doi: 10.1038/ng.2637.
    • (2013) Nat Genet. , vol.45 , pp. 822-824
    • Cordell, H.J.1    Bentham, J.2    Topf, A.3
  • 137
    • 84875272446 scopus 로고    scopus 로고
    • Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot
    • Cordell HJ, Töpf A, Mamasoula C, et al. Genome-wide association study identifies loci on 12q24 and 13q32 associated with tetralogy of Fallot. Hum Mol Genet. 2013;22:1473-1481. doi: 10.1093/hmg/dds552.
    • (2013) Hum Mol Genet. , vol.22 , pp. 1473-1481
    • Cordell, H.J.1
  • 139
    • 34250010480 scopus 로고    scopus 로고
    • A common variant on chromosome 9p21 affects the risk of myocardial infarction
    • Helgadottir A, Thorleifsson G, Manolescu A, et al. A common variant on chromosome 9p21 affects the risk of myocardial infarction. Science. 2007;316:1491-1493. doi: 10.1126/science.1142842.
    • (2007) Science. , vol.316 , pp. 1491-1493
    • Helgadottir, A.1    Thorleifsson, G.2    Manolescu, A.3


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