Heterogeneity of genetic modifiers ensures normal cardiac development

Circulation

Volumn 121, Issue 11, 2010, Pages 1313-1321

  Winston, Julia B ^a   Erlich, Jonathan M ^a   Green, Courtney A ^a   Aluko, Ashley ^a   Kaiser, Kristine A ^a   Takematsu, Mai ^a   Barlow, Robert S ^a   Sureka, Ashish O ^a   Lapage, Martin J ^a   Janss, Luc L ^b   Jay, Patrick Y ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Genetic variation; Genetics; Heart defects, congenital

Indexed keywords

TRANSCRIPTION FACTOR NKX2.5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONGENITAL HEART MALFORMATION; FEMALE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC HETEROGENEITY; GENETIC SUSCEPTIBILITY; HEART ATRIUM SEPTUM DEFECT; HEART DEVELOPMENT; HEART VENTRICLE SEPTUM DEFECT; MALE; MORBIDITY; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE NUCLEOTIDE POLYMORPHISM;

ANIMALS; DISEASE MODELS, ANIMAL; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HEART; HEART DEFECTS, CONGENITAL; HEART SEPTAL DEFECTS, ATRIAL; HEART SEPTAL DEFECTS, VENTRICULAR; HOMEODOMAIN PROTEINS; INCIDENCE; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MICE, KNOCKOUT; MUTATION; PHENOTYPE; RISK FACTORS; TRANSCRIPTION FACTORS;

EID: 77949808891     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.109.887687     Document Type: Article

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