A common genetic variant within SCN10A modulates cardiac SCN5A expression

Journal of Clinical Investigation

Volumn 124, Issue 4, 2014, Pages 1844-1852

  Van Den Boogaard, Malou ^a   Smemo, Scott ^b   Burnicka Turek, Ozanna ^b   Arnolds, David E ^b   Van De Werken, Harmen J G ^c   Klous, Petra ^d   McKean, David ^e   Muehlschlegel, Jochen D ^f   Moosmann, Julia ^g   Toka, Okan ^g   Yang, Xinan H ^b   Koopmann, Tamara T ^a   Adriaens, Michiel E ^a   Bezzina, Connie R ^a   De Laat, Wouter ^d   Seidman, Christine ^e   Seidman, J G ^e   Christoffels, Vincent M ^a   Nobrega, Marcelo A ^b   Barnett, Phil ^a   Moskowitz, Ivan P ^b   more..

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b UNIVERSITY OF CHICAGO   (United States)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e HARVARD MEDICAL SCHOOL   (United States)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

^g UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; SODIUM CHANNEL NAV1.5; SODIUM CHANNEL NAV1.8;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRUGADA SYNDROME; CONTROLLED STUDY; EMBRYO; ENHANCER REGION; GENE EXPRESSION; GENE INTERACTION; GENE LOCUS; GENETIC VARIABILITY; HAPLOTYPE MAP; HEART ARRHYTHMIA; HEART ATRIUM; HEART VENTRICLE; HEART VENTRICLE CONDUCTION; HISTOLOGY; HUMAN; HUMAN TISSUE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ANIMALS; ARRHYTHMIAS, CARDIAC; ENHANCER ELEMENTS, GENETIC; FEMALE; GENE EXPRESSION REGULATION; GENETIC VARIATION; HEART; HUMANS; MALE; MICE; MICE, TRANSGENIC; MYOCARDIUM; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; NAV1.8 VOLTAGE-GATED SODIUM CHANNEL; POLYMORPHISM, SINGLE NUCLEOTIDE; PREGNANCY; PROMOTER REGIONS, GENETIC; RNA, MESSENGER;

EID: 84897568607     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI73140     Document Type: Article

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