Transcriptional control: Rheostat converted to on/off switch

Molecular Cell

Volumn 6, Issue 3, 2000, Pages 723-728

  Rossi, Fabio M V ^a   Kringstein, Andrew M ^a   Spicher, Albert ^a   Guicherit, Oivin M ^b   Blau, Helen M ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Ontogeny Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

REPRESSOR PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VIRUS DNA;

ARTICLE; CELL ACTIVITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE EXPRESSION; GENE REPRESSION; GENE SWITCHING; MOLECULAR BIOLOGY; NONHUMAN; REGULATORY MECHANISM; RETROVIRUS; SIGNAL TRANSDUCTION; STIMULUS RESPONSE; TRANSACTIVATION; TRANSCRIPTION REGULATION;

UNIDENTIFIED RETROVIRUS;

EID: 0033638332     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)00070-8     Document Type: Article

References (35)

1. The eve stripe 2 enhancer employs multiple modes of transcriptional synergy
2. Mad: A heterodimeric partner for Max that antagonizes Myc transcriptional activity
3. Mad proteins contain a dominant transcription repression domain
4. XBF-1, a winged helix transcription factor with dual activity, has a role in positioning neurogenesis in Xenopus competent ectoderm
5. Why do protein kinase cascades have more than one level?
6. A mechanism for synergistic activation of a mammalian gene by GAL4 derivatives
7. The Tup1-Cyc8 protein complex can shift from a transcriptional corepressor to a transcriptional coactivator
8. Tetracycline-reversible silencing of eukaryotic promoters
9. Conversion of dorsal from an activator to a repressor by the global corepressor Groucho
10. The regulation of E2F by pRB-family proteins
11. Visualizing interleukin 2 gene expression at the single-cell level
12. How responses get more switch-like as you move down a protein kinase cascade
13. The biochemical basis of an all-or-none cell fate switch in Xenopus oocytes
14. Single-cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor
15. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
16. Transcriptional activation by tetracyclines in mammalian cells
17. Transcriptional repression in development
18. Cells' perception of position in a concentration gradient
19. An anteroposterior Dorsal gradient in the Drosophila embryo
20. The Drosophila gene brinker reveals a novel mechanism of Dpp target gene regulation
21. Measurement of ligand-induced activation in single viable T cells using the lacZ reporter gene
22. The dose dependence of glucocorticoid-inducible gene expression results from changes in the number of transcriptionally active templates
23. Graded transcriptional response to different concentrations of a single transactivator
24. An HMG-like protein that can switch a transcriptional activator to a repressor
25. The basic helix-loop-helix transcription factor Mist1 functions as a transcriptional repressor of myoD
26. How different eukaryotic transcriptional activators can cooperate promiscuously
27. MyoR: A muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of myoD
28. The nuclear receptor superfamily: The second decade
29. Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator
30. The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors
31. Tetracycline-regulatable factors with distinct dimerization domains allow reversible growth inhibition by p16
32. Regulation of even-skipped stripe 2 in the Drosophila embryo
33. Transcriptional regulation of a pair-rule stripe in Drosophila
34. Regulation of a segmentation stripe by overlapping activators and repressors in the Drosophila embryo
35. Signal-specific coactivator domain requirements for Pit-1 activation