Polycomb repressive complex 2 regulates normal development of the mouse heart

Circulation Research

Volumn 110, Issue 3, 2012, Pages 406-415

  He, Aibin ^a   Ma, Qing ^a   Cao, Jingjing ^a   Von Gise, Alexander ^a   Zhou, Pingzhu ^a   Xie, Huafeng ^a   Zhang, Bing ^a   Hsing, Michael ^a   Christodoulou, Danos C ^b   Cahan, Patrick ^c   Daley, George Q ^c,d   Kong, Sek Won ^a   Orkin, Stuart H ^a,c,d   Seidman, Christine E ^b,d   Seidman, Jonathan G ^b   Pu, William T ^a,c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HARVARD STEM CELL INSTITUTE   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

epigenomics; heart development; transcriptional regulation

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 10; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; HCN4 PROTEIN; IS11 PROTEIN; MLC2A PROTEIN; MYOSIN LIGHT CHAIN 2; POLYCOMB GROUP PROTEIN; POLYCOMB REPRESSIVE COMPLEX 2; PROTEIN; RNA; TRANSCRIPTION FACTOR EZH2; TRANSCRIPTION FACTOR NKX2.5; TRANSCRIPTION FACTOR PAX6; TRANSCRIPTION FACTOR SIX1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CHROMATIN IMMUNOPRECIPITATION; CONGENITAL HEART MALFORMATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ACTIVITY; EPIGENETICS; FETUS; FIBROBLAST; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE REPRESSION; GENETIC ASSOCIATION; GESTATIONAL AGE; HEART DEVELOPMENT; HEART DISEASE; HEART MUSCLE CELL; HEART VENTRICLE; HEART VENTRICLE SEPTUM DEFECT; HEMATOPOIETIC CELL; HYPERTRABECULATION; HYPOPLASIA; IMMUNOHISTOCHEMISTRY; LETHALITY; MOUSE; MYOCARDIAL DISEASE; NONHUMAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; UPREGULATION;

ANIMALS; CELL PROLIFERATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENOME-WIDE ASSOCIATION STUDY; HEART; HISTONE-LYSINE N-METHYLTRANSFERASE; HOMEODOMAIN PROTEINS; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MODELS, ANIMAL; MYOCYTES, CARDIAC; PROTEIN SUBUNITS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84856707310     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.111.252205     Document Type: Article

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