Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

Nature Communications

Volumn 6, Issue , 2015, Pages

  Wu, Hongtan ^a   Wei, Luyao ^a   Fan, Fuqin ^a   Ji, Suyuan ^a   Zhang, Shihao ^a   Geng, Jing ^a   Hong, Lixin ^a   Fan, Xin ^a   Chen, Qinghua ^a   Tian, Jing ^a   Jiang, Mingting ^a   Sun, Xiufeng ^a   Jin, Changnan ^b   Yin, Zhen Yu ^c   Liu, Qingxu ^a   Zhang, Jinjia ^a   Qin, Funiu ^a   Lin, Kwang Huei ^d   Yu, Jau Song ^d   Deng, Xianming ^a   Wang, Hong Rui ^a   Zhao, Bin ^e   Johnson, Randy L ^f   Chen, Lanfen ^a   Zhou, Dawang ^a   more..

^a XIAMEN UNIVERSITY   (China)

^b Xiamen Hospital of Traditional Chinese Medicine   (China)

^c ZHONGSHAN HOSPITAL OF XIAMEN UNIVERSITY   (China)

^d CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^e ZHEJIANG UNIVERSITY   (China)

^f UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INITIATION FACTOR 2; PROTEIN HIPPO; PROTEIN KINASE; TAUROURSODEOXYCHOLIC ACID; UNCLASSIFIED DRUG; ACTIVATING TRANSCRIPTION FACTOR 6; ATF6 PROTEIN, MOUSE; MACROPHAGE STIMULATING PROTEIN; MST2 PROTEIN, MOUSE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; ONCOPROTEIN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SCATTER FACTOR; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TAUROCHENODEOXYCHOLIC ACID; YAP PROTEIN, MOUSE;

CYTOLOGY; INHIBITION; MAMMAL; PROTEIN; SIGNAL; TUMOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER GROWTH; CARCINOGENESIS; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LIVER SIZE; MOUSE; NONHUMAN; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; ANIMAL; BIOLOGICAL MODEL; C57BL MOUSE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEPG2 CELL LINE; KNOCKOUT MOUSE; LIVER; LIVER CELL; LIVER TUMOR; METABOLISM; MOLECULAR GENETICS; MUTATION; ORGAN SIZE; PATHOLOGY; ULTRASTRUCTURE; WESTERN BLOTTING;

MAMMALIA;

ACTIVATING TRANSCRIPTION FACTOR 6; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CARCINOGENESIS; ENDOPLASMIC RETICULUM; HEP G2 CELLS; HEPATOCYTE GROWTH FACTOR; HEPATOCYTES; HUMANS; LIVER; LIVER NEOPLASMS; MICE, INBRED C57BL; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; ORGAN SIZE; PHOSPHOPROTEINS; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; TAUROCHENODEOXYCHOLIC ACID; TRANSCRIPTION, GENETIC; UNFOLDED PROTEIN RESPONSE;

EID: 84923362350     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7239     Document Type: Article

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