Rheb inhibits protein synthesis by activating the PERK-eIF2α signaling cascade

Cell Reports

Volumn 10, Issue 5, 2015, Pages 684-693

  Tyagi, Richa ^b   Shahani, Neelam ^a   Gorgen, Lindsay ^c   Ferretti, Max ^a   Pryor, William ^a   Chen, PoYu ^b   Swarnkar, Supriya ^a   Worley, Paul F ^b   Karbstein, Katrin ^a   Snyder, Solomon H ^b   Subramaniam, Srinivasa ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EUKARYOTIC TRANSLATION INITIATION FACTOR 2ALPHA; INITIATION FACTOR; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE LIKE ER KINASE; RHEB PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS INHIBITION; SIGNAL TRANSDUCTION; UNFOLDED PROTEIN RESPONSE; UPREGULATION;

EID: 84923329025     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2015.01.014     Document Type: Article

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