Suppression of eIF2α kinases alleviates Alzheimer's disease-related plasticity and memory deficits

Nature Neuroscience

Volumn 16, Issue 9, 2013, Pages 1299-1305

  Ma, Tao ^a   Trinh, Mimi A ^a   Wexler, Alyse J ^a   Bourbon, Clarisse ^b,c   Gatti, Evelina ^b,c   Pierre, Philippe ^b,c   Cavener, Douglas R ^d   Klann, Eric ^a  

^a NEW YORK UNIVERSITY   (United States)

^b CNRS   (France)

^c INSERM   (France)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; INITIATION FACTOR 2ALPHA; PRESENILIN 1; PROTEIN KINASE R;

ADULT; AGED; ALZHEIMER DISEASE; AMNESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME REPRESSION; FEMALE; GENE DELETION; GENE MUTATION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MALE; MOLECULAR MECHANICS; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; SPATIAL MEMORY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANISOMYCIN; DISEASE MODELS, ANIMAL; EIF-2 KINASE; FEMALE; HIPPOCAMPUS; HUMANS; MALE; MAZE LEARNING; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NEURONAL PLASTICITY; PRESENILIN-1; PROTEIN SYNTHESIS INHIBITORS; RECOGNITION (PSYCHOLOGY);

EID: 84883453343     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3486     Document Type: Article

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