Differing effects of rapamycin and mTOR kinase inhibitors on protein synthesis

Biochemical Society Transactions

Volumn 39, Issue 2, 2011, Pages 446-450

  Huo, Yilin ^a   Iadevaia, Valentina ^a   Proud, Christopher G ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

5 terminal oligopyrimidine tract (5 TOP); Mammalian target of rapamycin (mTOR); mRNA; Pulsed stable isotope labelling of proteins with amino acids in cell culture (pSILAC); Rapamycin; Translation

Indexed keywords

INITIATION FACTOR 4A; INITIATION FACTOR 4E; INITIATION FACTOR 4E BINDING PROTEIN 1; INITIATION FACTOR 4G; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MESSENGER RNA; PROTEIN SERINE THREONINE KINASE; RAPAMYCIN;

5' UNTRANSLATED REGION; ANTINEOPLASTIC ACTIVITY; CANCER CELL; ENZYME INHIBITION; HELA CELL; HUMAN; ISOTOPE LABELING; PRIORITY JOURNAL; PROTEIN SYNTHESIS; PROTEIN SYNTHESIS INHIBITION; REVIEW; TERMINAL OLIGOPYRIMIDINE TRACT; TRANSLATION REGULATION;

ANIMALS; HUMANS; ISOTOPE LABELING; MODELS, BIOLOGICAL; PROTEIN BIOSYNTHESIS; PROTEIN KINASE INHIBITORS; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EUKARYOTA; MAMMALIA;

EID: 79953183694     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0390446     Document Type: Review

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