Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 45, Issue 6, 2008, Pages 812-820

  Wang, Yanni ^a   Huang, Brandon P H ^a   Luciani, Dan S ^a   Wang, Xuemin ^a   Johnson, James D ^a   Proud, Christopher G ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

Author keywords

Cardiac hypertrophy; Growth; mTOR; Protein synthesis; Rheb

Indexed keywords

ADENOVIRUS VECTOR; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; GUANOSINE TRIPHOSPHATE; INITIATION FACTOR 4E; MAMMALIAN TARGET OF RAPAMYCIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; METHIONINE; PHENYLALANINE; PHENYLEPHRINE; RAPAMYCIN; RHEB PROTEIN; RNA; SULFUR 35; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GEL ELECTROPHORESIS; HEART HYPERTROPHY; HEART MUSCLE CELL; HEART VENTRICLE; ISOTOPE LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ADENOVIRIDAE; ANIMALS; ANTI-BACTERIAL AGENTS; ATRIAL NATRIURETIC FACTOR; BIOLOGICAL MARKERS; CARDIOMEGALY; CARDIOTONIC AGENTS; CELL PROLIFERATION; CELL SIZE; CELLS, CULTURED; GENETIC VECTORS; HEART VENTRICLES; MALE; MONOMERIC GTP-BINDING PROTEINS; MYOCYTES, CARDIAC; NATRIURETIC PEPTIDE, BRAIN; NEUROPEPTIDES; PHENYLEPHRINE; PROTEIN BIOSYNTHESIS; PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SIROLIMUS;

MAMMALIA; RATTUS;

EID: 55649092252     PISSN: 00222828     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2008.07.016     Document Type: Article

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