ER stress-induced eIF2-alpha phosphorylation underlies sensitivity of striatal neurons to pathogenic huntingtin

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Leitman, Julia ^a   Barak, Boaz ^a   Benyair, Ron ^a   Shenkman, Marina ^a   Ashery, Uri ^a   Hartl, F Ulrich ^b   Lederkremer, Gerardo Z ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; INITIATION FACTOR; TRANSCRIPTION FACTOR ELF2 ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; BRAIN REGION; CELL LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; EMBRYO; ENDOPLASMIC RETICULUM STRESS; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; MALE; MOUSE; NERVE CELL CULTURE; NEUROPATHOLOGY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS;

ANIMALS; DNA PRIMERS; ENDOPLASMIC RETICULUM STRESS; EUKARYOTIC INITIATION FACTOR-2; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GENETIC VECTORS; HEK293 CELLS; HUMANS; IMMUNOBLOTTING; MICE; NERVE TISSUE PROTEINS; NEURONS; NIH 3T3 CELLS; NUCLEAR PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VISUAL CORTEX;

EID: 84897002606     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090803     Document Type: Article

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