-
1
-
-
0031692336
-
The caveolae membrane system
-
Anderson RG. 1998. The caveolae membrane system. Annu Rev Biochem 67:199-225.
-
(1998)
Annu Rev Biochem
, vol.67
, pp. 199-225
-
-
Anderson, R.G.1
-
2
-
-
67649470380
-
Proximal events in Wnt signal transduction
-
Angers S, Moon RT. 2009. Proximal events in Wnt signal transduction. Nat Rev Mol Cell Biol 10:468-477.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 468-477
-
-
Angers, S.1
Moon, R.T.2
-
3
-
-
0034933057
-
Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow
-
Bafico A, Liu G, Yaniv A, Gazit A, Aaronson SA. 2001. Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow. Nat Cell Biol 3:683-686.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 683-686
-
-
Bafico, A.1
Liu, G.2
Yaniv, A.3
Gazit, A.4
Aaronson, S.A.5
-
4
-
-
35548974423
-
Identification of stem cells in small intestine and colon by marker gene Lgr5
-
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. 2007. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449:1003-1007.
-
(2007)
Nature
, vol.449
, pp. 1003-1007
-
-
Barker, N.1
van Es, J.H.2
Kuipers, J.3
Kujala, P.4
van den Born, M.5
Cozijnsen, M.6
Haegebarth, A.7
Korving, J.8
Begthel, H.9
Peters, P.J.10
Clevers, H.11
-
5
-
-
34250827150
-
Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation
-
Bilic J, Huang YL, Davidson G, Zimmermann T, Cruciat CM, Bienz M, Niehrs C. 2007. Wnt induces LRP6 signalosomes and promotes dishevelled-dependent LRP6 phosphorylation. Science 316:1619-1622.
-
(2007)
Science
, vol.316
, pp. 1619-1622
-
-
Bilic, J.1
Huang, Y.L.2
Davidson, G.3
Zimmermann, T.4
Cruciat, C.M.5
Bienz, M.6
Niehrs, C.7
-
6
-
-
35548966679
-
R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6
-
Binnerts ME, Kim KA, Bright JM, Patel SM, Tran K, Zhou M, Leung JM, Liu Y, Lomas WE, Dixon M, Hazell SA, Wagle M, Nie WS, Tomasevic N, Williams J, Zhan X, Levy MD, Funk WD, Abo A. 2007. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proc Natl Acad Sci USA 104:14700-14705.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 14700-14705
-
-
Binnerts, M.E.1
Kim, K.A.2
Bright, J.M.3
Patel, S.M.4
Tran, K.5
Zhou, M.6
Leung, J.M.7
Liu, Y.8
Lomas, W.E.9
Dixon, M.10
Hazell, S.A.11
Wagle, M.12
Nie, W.S.13
Tomasevic, N.14
Williams, J.15
Zhan, X.16
Levy, M.D.17
Funk, W.D.18
Abo, A.19
-
7
-
-
33746960721
-
A critical role for endocytosis in Wnt signaling
-
Blitzer JT, Nusse R. 2006. A critical role for endocytosis in Wnt signaling. BMC Cell Biol 7:28.
-
(2006)
BMC Cell Biol
, vol.7
, pp. 28
-
-
Blitzer, J.T.1
Nusse, R.2
-
8
-
-
0032967755
-
Dishevelled: At the crossroads of divergent intracellular signaling pathways
-
Boutros M, Mlodzik M. 1999. Dishevelled: At the crossroads of divergent intracellular signaling pathways. Mech Dev 83:27-37.
-
(1999)
Mech Dev
, vol.83
, pp. 27-37
-
-
Boutros, M.1
Mlodzik, M.2
-
9
-
-
77149174855
-
Wnt signaling from development to disease: Insights from model systems
-
Cadigan KM, Peifer M. 2009. Wnt signaling from development to disease: Insights from model systems. Cold Spring Harb Perspect Biol 1:a002881.
-
(2009)
Cold Spring Harb Perspect Biol
, vol.1
, pp. a002881
-
-
Cadigan, K.M.1
Peifer, M.2
-
10
-
-
0037126331
-
The DIX domain targets dishevelled to actin stress fibres and vesicular membranes
-
Capelluto DG, Kutateladze TG, Habas R, Finkielstein CV, He X, Overduin M. 2002. The DIX domain targets dishevelled to actin stress fibres and vesicular membranes. Nature 419:726-729.
-
(2002)
Nature
, vol.419
, pp. 726-729
-
-
Capelluto, D.G.1
Kutateladze, T.G.2
Habas, R.3
Finkielstein, C.V.4
He, X.5
Overduin, M.6
-
11
-
-
79960990066
-
R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling
-
Carmon KS, Gong X, Lin Q, Thomas A, Liu Q. 2011. R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling. Proc Natl Acad Sci USA 108:11452-11457.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 11452-11457
-
-
Carmon, K.S.1
Gong, X.2
Lin, Q.3
Thomas, A.4
Liu, Q.5
-
12
-
-
84864021917
-
LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β -catenin signaling
-
Carmon KS, Lin Q, Gong X, Thomas A, Liu Q. 2012. LGR5 interacts and cointernalizes with Wnt receptors to modulate Wnt/β -catenin signaling. Mol Cell Biol 32:2054-2064.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 2054-2064
-
-
Carmon, K.S.1
Lin, Q.2
Gong, X.3
Thomas, A.4
Liu, Q.5
-
13
-
-
0041470133
-
Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4
-
Chen W, ten Berge, Brown D, Ahn J, Hu S, Miller LA, Caron WE, Barak MG, Nusse LS, Lefkowitz R. 2003. Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4. Science 301:1391-1394.
-
(2003)
Science
, vol.301
, pp. 1391-1394
-
-
Chen, W.1
ten, B.2
Brown, D.3
Ahn, J.4
Hu, S.5
Miller, L.A.6
Caron, W.E.7
Barak, M.G.8
Nusse, L.S.9
Lefkowitz, R.10
-
14
-
-
84907487414
-
Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control
-
Clevers H, Loh KM, Nusse R. 2014. Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science 346:1248012.
-
(2014)
Science
, vol.346
, pp. 1248012
-
-
Clevers, H.1
Loh, K.M.2
Nusse, R.3
-
15
-
-
84861986053
-
Wnt/β -catenin signaling and disease
-
Clevers H, Nusse R. 2012. Wnt/β -catenin signaling and disease. Cell 149:1192-1205.
-
(2012)
Cell
, vol.149
, pp. 1192-1205
-
-
Clevers, H.1
Nusse, R.2
-
16
-
-
8444223093
-
Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors. Frizzled and LRP
-
Cong F, Schweizer L, Varmus H. 2004. Wnt signals across the plasma membrane to activate the beta-catenin pathway by forming oligomers containing its receptors. Frizzled and LRP. Development 131:5103-5115.
-
(2004)
Development
, vol.131
, pp. 5103-5115
-
-
Cong, F.1
Schweizer, L.2
Varmus, H.3
-
17
-
-
0042733637
-
Differential requirements for AP-2 in clathrin-mediated endocytosis
-
Conner SD, Schmid SL. 2003. Differential requirements for AP-2 in clathrin-mediated endocytosis. J Cell Biol 162:773-779.
-
(2003)
J Cell Biol
, vol.162
, pp. 773-779
-
-
Conner, S.D.1
Schmid, S.L.2
-
18
-
-
45849104800
-
LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin
-
Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E. 2008. LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin. Proc Natl Acad Sci USA 105:8032-8037.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8032-8037
-
-
Cselenyi, C.S.1
Jernigan, K.K.2
Tahinci, E.3
Thorne, C.A.4
Lee, L.A.5
Lee, E.6
-
19
-
-
84870657185
-
Wntless in Wnt secretion: Molecular, cellular and genetic aspects
-
Das S, Yu S, Sakamori R, Stypulkowski E, Gao N. 2012. Wntless in Wnt secretion: Molecular, cellular and genetic aspects. Front Biol (Beijing) 7:587-593.
-
(2012)
Front Biol (Beijing)
, vol.7
, pp. 587-593
-
-
Das, S.1
Yu, S.2
Sakamori, R.3
Stypulkowski, E.4
Gao, N.5
-
20
-
-
28644444440
-
Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction
-
Davidson G, Wu W, Shen J, Bilic J, Fenger U, Stannek P, Glinka A, Niehrs C. 2005. Casein kinase 1 gamma couples Wnt receptor activation to cytoplasmic signal transduction. Nature 438:867-872.
-
(2005)
Nature
, vol.438
, pp. 867-872
-
-
Davidson, G.1
Wu, W.2
Shen, J.3
Bilic, J.4
Fenger, U.5
Stannek, P.6
Glinka, A.7
Niehrs, C.8
-
21
-
-
80051926611
-
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling
-
de Lau W, Barker N, Low TY, Koo BK, Li VS, Teunissen H, Kujala P, Haegebarth A, Peters PJ, van de Wetering M, Stange DE, van Es JE, Guardavaccaro D, Schasfoort RB, Mohri Y, Nishimori K, Mohammed S, Heck AJ, Clevers H. 2011. Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling. Nature 476:293-297.
-
(2011)
Nature
, vol.476
, pp. 293-297
-
-
de Lau, W.1
Barker, N.2
Low, T.Y.3
Koo, B.K.4
Li, V.S.5
Teunissen, H.6
Kujala, P.7
Haegebarth, A.8
Peters, P.J.9
van de Wetering, M.10
Stange, D.E.11
van Es, J.E.12
Guardavaccaro, D.13
Schasfoort, R.B.14
Mohri, Y.15
Nishimori, K.16
Mohammed, S.17
Heck, A.J.18
Clevers, H.19
-
22
-
-
84884594963
-
RAB8B is required for activity and caveolar endocytosis of LRP6
-
Demir K, Kirsch N, Beretta CA, Erdmann G, Ingelfinger D, Moro E, Argenton F, Carl M, Niehrs C, Boutros M. 2013. RAB8B is required for activity and caveolar endocytosis of LRP6. Cell Rep 4:1224-1234.
-
(2013)
Cell Rep
, vol.4
, pp. 1224-1234
-
-
Demir, K.1
Kirsch, N.2
Beretta, C.A.3
Erdmann, G.4
Ingelfinger, D.5
Moro, E.6
Argenton, F.7
Carl, M.8
Niehrs, C.9
Boutros, M.10
-
23
-
-
84355162786
-
Endocytic control of growth factor signalling: Multivesicular bodies as signalling organelles
-
Dobrowolski R, De Robertis EM. 2012. Endocytic control of growth factor signalling: Multivesicular bodies as signalling organelles. Nat Rev Mol Cell Biol 13:53-60.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 53-60
-
-
Dobrowolski, R.1
De Robertis, E.M.2
-
24
-
-
84870407757
-
Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment
-
Dobrowolski R, Vick P, Ploper D, Gumper I, Snitkin H, Sabatini DD, De Robertis EM. 2012. Presenilin deficiency or lysosomal inhibition enhances Wnt signaling through relocalization of GSK3 to the late-endosomal compartment. Cell Rep 2:1316-1328.
-
(2012)
Cell Rep
, vol.2
, pp. 1316-1328
-
-
Dobrowolski, R.1
Vick, P.2
Ploper, D.3
Gumper, I.4
Snitkin, H.5
Sabatini, D.D.6
De Robertis, E.M.7
-
25
-
-
0035368514
-
Regulated endocytic routing modulates wingless signaling in Drosophila embryos
-
Dubois L, Lecourtois M, Alexandre C, Hirst E, Vincent JP. 2001. Regulated endocytic routing modulates wingless signaling in Drosophila embryos. Cell 105:613-624.
-
(2001)
Cell
, vol.105
, pp. 613-624
-
-
Dubois, L.1
Lecourtois, M.2
Alexandre, C.3
Hirst, E.4
Vincent, J.P.5
-
26
-
-
0030458493
-
Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila
-
Eaton S, Wepf R, Simons K. 1996. Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila. J Cell Biol 135:1277-1289.
-
(1996)
J Cell Biol
, vol.135
, pp. 1277-1289
-
-
Eaton, S.1
Wepf, R.2
Simons, K.3
-
27
-
-
0034710614
-
Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye
-
Fanto M, Weber U, Strutt DI, Mlodzik M. 2000. Nuclear signaling by Rac and Rho GTPases is required in the establishment of epithelial planar polarity in the Drosophila eye. Curr Biol 10:979-988.
-
(2000)
Curr Biol
, vol.10
, pp. 979-988
-
-
Fanto, M.1
Weber, U.2
Strutt, D.I.3
Mlodzik, M.4
-
28
-
-
80053560465
-
LGR4 and LGR5 are R-spondin receptors mediating Wnt/β -catenin and Wnt/PCP signalling
-
Glinka A, Dolde C, Kirsch N, Huang YL, Kazanskaya O, Ingelfinger D, Boutros M, Cruciat CM, Niehrs C. 2011. LGR4 and LGR5 are R-spondin receptors mediating Wnt/β -catenin and Wnt/PCP signalling. EMBO Rep 12:1055-1061.
-
(2011)
EMBO Rep
, vol.12
, pp. 1055-1061
-
-
Glinka, A.1
Dolde, C.2
Kirsch, N.3
Huang, Y.L.4
Kazanskaya, O.5
Ingelfinger, D.6
Boutros, M.7
Cruciat, C.M.8
Niehrs, C.9
-
29
-
-
0032556910
-
Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
-
Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. 1998. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391:357-362.
-
(1998)
Nature
, vol.391
, pp. 357-362
-
-
Glinka, A.1
Wu, W.2
Delius, H.3
Monaghan, A.P.4
Blumenstock, C.5
Niehrs, C.6
-
30
-
-
0029770657
-
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
-
Goodman OB, Krupnick JG, Santini F, Gurevich VV, Penn RB, Gagnon AW, Keen JH, Benovic JL. 1996. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor. Nature 383:447-450.
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman, O.B.1
Krupnick, J.G.2
Santini, F.3
Gurevich, V.V.4
Penn, R.B.5
Gagnon, A.W.6
Keen, J.H.7
Benovic, J.L.8
-
31
-
-
78349276165
-
Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors
-
Grumolato L, Liu G, Mong P, Mudbhary R, Biswas R, Arroyave R, Vijayakumar S, Economides AN, Aaronson SA. 2010. Canonical and noncanonical Wnts use a common mechanism to activate completely unrelated coreceptors. Genes Dev 24:2517-2530.
-
(2010)
Genes Dev
, vol.24
, pp. 2517-2530
-
-
Grumolato, L.1
Liu, G.2
Mong, P.3
Mudbhary, R.4
Biswas, R.5
Arroyave, R.6
Vijayakumar, S.7
Economides, A.N.8
Aaronson, S.A.9
-
32
-
-
33646545075
-
Re-routing of the invariant chain to the direct sorting pathway by introduction of an AP3-binding motif from LIMP II
-
Gupta SN, Kloster MM, Rodionov DG, Bakke O. 2006. Re-routing of the invariant chain to the direct sorting pathway by introduction of an AP3-binding motif from LIMP II. Eur J Cell Biol 85:457-467.
-
(2006)
Eur J Cell Biol
, vol.85
, pp. 457-467
-
-
Gupta, S.N.1
Kloster, M.M.2
Rodionov, D.G.3
Bakke, O.4
-
33
-
-
0037439138
-
Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
-
Habas R, Dawid IB, He X. 2003. Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev 17:295-309.
-
(2003)
Genes Dev
, vol.17
, pp. 295-309
-
-
Habas, R.1
Dawid, I.B.2
He, X.3
-
34
-
-
0035966322
-
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1
-
Habas R, Kato Y, He X. 2001. Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1. Cell 107:843-854.
-
(2001)
Cell
, vol.107
, pp. 843-854
-
-
Habas, R.1
Kato, Y.2
He, X.3
-
35
-
-
84907042839
-
In vivo analysis of formation and endocytosis of the Wnt/β -Catenin signaling complex in zebrafish embryos
-
Hagemann AI, Kurz J, Kauffeld S, Chen Q, Reeves PM, Weber S, Schindler S, Davidson G, Kirchhausen T, Scholpp S. 2014. In vivo analysis of formation and endocytosis of the Wnt/β -Catenin signaling complex in zebrafish embryos. J Cell Sci 127:3970-3982.
-
(2014)
J Cell Sci
, vol.127
, pp. 3970-3982
-
-
Hagemann, A.I.1
Kurz, J.2
Kauffeld, S.3
Chen, Q.4
Reeves, P.M.5
Weber, S.6
Schindler, S.7
Davidson, G.8
Kirchhausen, T.9
Scholpp, S.10
-
36
-
-
84860765166
-
ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
-
Hao HX, Xie Y, Zhang Y, Charlat O, Oster E, Avello M, Lei H, Mickanin C, Liu D, Ruffner H, Mao X, Ma Q, Zamponi R, Bouwmeester T, Finan PM, Kirschner MW, Porter JA, Serluca FC, Cong F. 2012. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature 485:195-200.
-
(2012)
Nature
, vol.485
, pp. 195-200
-
-
Hao, H.X.1
Xie, Y.2
Zhang, Y.3
Charlat, O.4
Oster, E.5
Avello, M.6
Lei, H.7
Mickanin, C.8
Liu, D.9
Ruffner, H.10
Mao, X.11
Ma, Q.12
Zamponi, R.13
Bouwmeester, T.14
Finan, P.M.15
Kirschner, M.W.16
Porter, J.A.17
Serluca, F.C.18
Cong, F.19
-
37
-
-
2342430345
-
LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way
-
He X, Semenov M, Tamai K, Zeng X. 2004. LDL receptor-related proteins 5 and 6 in Wnt/beta-catenin signaling: arrows point the way. Development 131:1663-1677.
-
(2004)
Development
, vol.131
, pp. 1663-1677
-
-
He, X.1
Semenov, M.2
Tamai, K.3
Zeng, X.4
-
38
-
-
0033429706
-
Participation of dynamin in the biogenesis of cytoplasmic vesicles
-
Henley JR, Cao H, McNiven MA. 1999. Participation of dynamin in the biogenesis of cytoplasmic vesicles. FASEB J 13:S243-S247.
-
(1999)
FASEB J
, vol.13
, pp. S243-S247
-
-
Henley, J.R.1
Cao, H.2
McNiven, M.A.3
-
39
-
-
0033118492
-
A new secreted protein that binds to Wnt proteins and inhibits their activities
-
Hsieh JC, Kodjabachian L, Rebbert ML, Rattner A, Smallwood PM, Samos CH, Nusse R, Dawid IB, Nathans J. 1999. A new secreted protein that binds to Wnt proteins and inhibits their activities. Nature 398:431-436.
-
(1999)
Nature
, vol.398
, pp. 431-436
-
-
Hsieh, J.C.1
Kodjabachian, L.2
Rebbert, M.L.3
Rattner, A.4
Smallwood, P.M.5
Samos, C.H.6
Nusse, R.7
Dawid, I.B.8
Nathans, J.9
-
40
-
-
41549115361
-
Wnt/beta-catenin signaling: new (and old) players and new insights
-
Huang H, He X. 2008. Wnt/beta-catenin signaling: new (and old) players and new insights. Curr Opin Cell Biol 20:119-125.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 119-125
-
-
Huang, H.1
He, X.2
-
41
-
-
39149132089
-
ESCRT complexes and the biogenesis of multivesicular bodies
-
Hurley JH. 2008. ESCRT complexes and the biogenesis of multivesicular bodies. Curr Opin Cell Biol 20:4-11.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 4-11
-
-
Hurley, J.H.1
-
42
-
-
55049112939
-
Lgr5 marks cycling, yet long-lived, hair follicle stem cells
-
Jaks V, Barker N, Kasper M, van Es JH, Snippert HJ, Clevers H, Toftgård R. 2008. Lgr5 marks cycling, yet long-lived, hair follicle stem cells. Nat Genet 40:1291-1299.
-
(2008)
Nat Genet
, vol.40
, pp. 1291-1299
-
-
Jaks, V.1
Barker, N.2
Kasper, M.3
van Es, J.H.4
Snippert, H.J.5
Clevers, H.6
Toftgård, R.7
-
43
-
-
84881112879
-
Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma
-
Jiang X, Hao HX, Growney JD, Woolfenden S, Bottiglio C, Ng N, Lu B, Hsieh MH, Bagdasarian L, Meyer R, Smith TR, Avello M, Charlat O, Xie Y, Porter JA, Pan S, Liu J, McLaughlin ME, Cong F. 2013. Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma. Proc Natl Acad Sci USA 110:12649-12654.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 12649-12654
-
-
Jiang, X.1
Hao, H.X.2
Growney, J.D.3
Woolfenden, S.4
Bottiglio, C.5
Ng, N.6
Lu, B.7
Hsieh, M.H.8
Bagdasarian, L.9
Meyer, R.10
Smith, T.R.11
Avello, M.12
Charlat, O.13
Xie, Y.14
Porter, J.A.15
Pan, S.16
Liu, J.17
McLaughlin, M.E.18
Cong, F.19
-
44
-
-
84861195598
-
Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin
-
Jiang Y, He X, Howe PH. 2012. Disabled-2 (Dab2) inhibits Wnt/β-catenin signalling by binding LRP6 and promoting its internalization through clathrin. EMBO J 31:2336-2349.
-
(2012)
EMBO J
, vol.31
, pp. 2336-2349
-
-
Jiang, Y.1
He, X.2
Howe, P.H.3
-
45
-
-
83555162471
-
Waif1/5T4 inhibits Wnt/β -catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization
-
Kagermeier-Schenk B, Wehner D, Ozhan-Kizil G, Yamamoto H, Li J, Kirchner K, Hoffmann C, Stern P, Kikuchi A, Schambony A, Weidinger G. 2011. Waif1/5T4 inhibits Wnt/β -catenin signaling and activates noncanonical Wnt pathways by modifying LRP6 subcellular localization. Dev Cell 21:1129-1143.
-
(2011)
Dev Cell
, vol.21
, pp. 1129-1143
-
-
Kagermeier-Schenk, B.1
Wehner, D.2
Ozhan-Kizil, G.3
Yamamoto, H.4
Li, J.5
Kirchner, K.6
Hoffmann, C.7
Stern, P.8
Kikuchi, A.9
Schambony, A.10
Weidinger, G.11
-
46
-
-
5044244757
-
R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis
-
Kazanskaya O, Glinka A, del Barco Barrantes, I, Stannek P, Niehrs C, Wu W. 2004. R-Spondin2 is a secreted activator of Wnt/beta-catenin signaling and is required for Xenopus myogenesis. Dev Cell 7:525-534.
-
(2004)
Dev Cell
, vol.7
, pp. 525-534
-
-
Kazanskaya, O.1
Glinka, A.2
del Barco Barrantes, I.3
Stannek, P.4
Niehrs, C.5
Wu, W.6
-
47
-
-
61449249121
-
Selective activation mechanisms of Wnt signaling pathways
-
Kikuchi A, Yamamoto H, Sato A. 2009. Selective activation mechanisms of Wnt signaling pathways. Trends Cell Biol 19:119-129.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 119-129
-
-
Kikuchi, A.1
Yamamoto, H.2
Sato, A.3
-
48
-
-
84874384373
-
Clathrin and AP2 are required for PtdIns(4
-
Kim I, Pan W, Jones SA, Zhang Y, Zhuang X, Wu D. 2013. Clathrin and AP2 are required for PtdIns(4. 5)P2-mediated formation of LRP6 signalosomes. 200:419-428.
-
(2013)
5)P2-mediated formation of LRP6 signalosomes.
, vol.200
, pp. 419-428
-
-
Kim, I.1
Pan, W.2
Jones, S.A.3
Zhang, Y.4
Zhuang, X.5
Wu, D.6
-
49
-
-
23844455584
-
Mitogenic influence of human R-spondin1 on the intestinal epithelium
-
Kim KA, Kakitani M, Zhao J, Oshima T, Tang T, Binnerts M, Liu Y, Boyle B, Park E, Emtage P, Funk WD, Tomizuka K. 2005. Mitogenic influence of human R-spondin1 on the intestinal epithelium. Science 309:1256-1259.
-
(2005)
Science
, vol.309
, pp. 1256-1259
-
-
Kim, K.A.1
Kakitani, M.2
Zhao, J.3
Oshima, T.4
Tang, T.5
Binnerts, M.6
Liu, Y.7
Boyle, B.8
Park, E.9
Emtage, P.10
Funk, W.D.11
Tomizuka, K.12
-
50
-
-
84899480869
-
Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice
-
Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Müller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS. 2014. Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol 390:181-190.
-
(2014)
Dev Biol
, vol.390
, pp. 181-190
-
-
Kinzel, B.1
Pikiolek, M.2
Orsini, V.3
Sprunger, J.4
Isken, A.5
Zietzling, S.6
Desplanches, M.7
Dubost, V.8
Breustedt, D.9
Valdez, R.10
Liu, D.11
Theil, D.12
Müller, M.13
Dietrich, B.14
Bouwmeester, T.15
Ruffner, H.16
Tchorz, J.S.17
-
51
-
-
0033280324
-
Adaptors for clathrin-mediated traffic
-
Kirchhausen T. 1999. Adaptors for clathrin-mediated traffic. Annu Rev Cell Dev Biol 15:705-732.
-
(1999)
Annu Rev Cell Dev Biol
, vol.15
, pp. 705-732
-
-
Kirchhausen, T.1
-
52
-
-
84865782103
-
Bending membranes
-
T. Kirchhausen, Bending membranes Nat Cell Biol 14: 2012; 906-908.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 906-908
-
-
Kirchhausen, T.1
-
53
-
-
84865517676
-
Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
-
Koo BK, Spit M, Jordens I, Low TY, Stange DE, van de Wetering M, van Es JH, Mohammed S, Heck AJ, Maurice MM, Clevers H. 2012. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature 488:665-669.
-
(2012)
Nature
, vol.488
, pp. 665-669
-
-
Koo, B.K.1
Spit, M.2
Jordens, I.3
Low, T.Y.4
Stange, D.E.5
van de Wetering, M.6
van Es, J.H.7
Mohammed, S.8
Heck, A.J.9
Maurice, M.M.10
Clevers, H.11
-
54
-
-
33847353371
-
Phosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signalling
-
Krauss M, Haucke V. 2007. Phosphoinositide-metabolizing enzymes at the interface between membrane traffic and cell signalling. EMBO Rep 8:241-246.
-
(2007)
EMBO Rep
, vol.8
, pp. 241-246
-
-
Krauss, M.1
Haucke, V.2
-
55
-
-
77957895194
-
Lipid rafts, caveolae, and their endocytosis
-
Lajoie P, Nabi IR. 2010. Lipid rafts, caveolae, and their endocytosis. Int Rev Cell Mol Biol 282:135-163.
-
(2010)
Int Rev Cell Mol Biol
, vol.282
, pp. 135-163
-
-
Lajoie, P.1
Nabi, I.R.2
-
56
-
-
84875153351
-
Wnt signaling in skin development, homeostasis, and disease
-
Lim X, Nusse R. 2013. Wnt signaling in skin development, homeostasis, and disease. Cold Spring Harb Perspect Biol 5:a008029.
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
, pp. a008029
-
-
Lim, X.1
Nusse, R.2
-
57
-
-
0035368394
-
G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway
-
Liu T, DeCostanzo AJ, Liu X, Wang Hy, Hallagan S, Moon RT, Malbon CC. 2001. G protein signaling from activated rat frizzled-1 to the beta-catenin-Lef-Tcf pathway. Science 292:1718-1722.
-
(2001)
Science
, vol.292
, pp. 1718-1722
-
-
Liu, T.1
DeCostanzo, A.J.2
Liu, X.3
Wang, H.4
Hallagan, S.5
Moon, R.T.6
Malbon, C.C.7
-
58
-
-
14544303674
-
Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2
-
Luo CW, Dewey EM, Sudo S, Ewer J, Hsu SY, Honegger HW, Hsueh AJ. 2005. Bursicon, the insect cuticle-hardening hormone, is a heterodimeric cystine knot protein that activates G protein-coupled receptor LGR2. Proc Natl Acad Sci U S A 102:2820-2825.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2820-2825
-
-
Luo, C.W.1
Dewey, E.M.2
Sudo, S.3
Ewer, J.4
Hsu, S.Y.5
Honegger, H.W.6
Hsueh, A.J.7
-
59
-
-
84870727005
-
Frizzled and LRP5/6 receptors for Wnt/β -catenin signaling
-
MacDonald BT, He X. 2012. Frizzled and LRP5/6 receptors for Wnt/β -catenin signaling. Cold Spring Harb Perspect Biol 4:a007880.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
, pp. a007880
-
-
MacDonald, B.T.1
He, X.2
-
60
-
-
67650230896
-
Wnt/beta-catenin signaling: components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X. 2009. Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev Cell 17:9-26.
-
(2009)
Dev Cell
, vol.17
, pp. 9-26
-
-
MacDonald, B.T.1
Tamai, K.2
He, X.3
-
61
-
-
47049121052
-
Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6
-
MacDonald BT, Yokota C, Tamai K, Zeng X, He X. 2008. Wnt signal amplification via activity, cooperativity, and regulation of multiple intracellular PPPSP motifs in the Wnt co-receptor LRP6. J Biol Chem 283:16115-16123.
-
(2008)
J Biol Chem
, vol.283
, pp. 16115-16123
-
-
MacDonald, B.T.1
Yokota, C.2
Tamai, K.3
Zeng, X.4
He, X.5
-
62
-
-
0037413696
-
Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling
-
Mao B, Niehrs C. 2003. Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling. Gene 302:179-183.
-
(2003)
Gene
, vol.302
, pp. 179-183
-
-
Mao, B.1
Niehrs, C.2
-
63
-
-
18244427021
-
Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway
-
Mao J, Wang J, Liu B, Pan W, Farr GH, Flynn C, Yuan H, Takada S, Kimelman D, Li L, Wu D. 2001b. Low-density lipoprotein receptor-related protein-5 binds to Axin and regulates the canonical Wnt signaling pathway. Mol Cell 7:801-809.
-
(2001)
Mol Cell
, vol.7
, pp. 801-809
-
-
Mao, J.1
Wang, J.2
Liu, B.3
Pan, W.4
Farr, G.H.5
Flynn, C.6
Yuan, H.7
Takada, S.8
Kimelman, D.9
Li, L.10
Wu, D.11
-
64
-
-
0037030681
-
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling
-
Mao B, Wu W, Davidson G, Marhold J, Li M, Mechler BM, Delius H, Hoppe D, Stannek P, Walter C, Glinka A, Niehrs C. 2002. Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling. Nature 417:664-667.
-
(2002)
Nature
, vol.417
, pp. 664-667
-
-
Mao, B.1
Wu, W.2
Davidson, G.3
Marhold, J.4
Li, M.5
Mechler, B.M.6
Delius, H.7
Hoppe, D.8
Stannek, P.9
Walter, C.10
Glinka, A.11
Niehrs, C.12
-
65
-
-
0035902050
-
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
-
Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C. 2001. LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411:321-325.
-
(2001)
Nature
, vol.411
, pp. 321-325
-
-
Mao, B.1
Wu, W.2
Li, Y.3
Hoppe, D.4
Stannek, P.5
Glinka, A.6
Niehrs, C.7
-
66
-
-
0033538576
-
The structural era of endocytosis
-
Marsh M, McMahon HT. 1999. The structural era of endocytosis. Science 285:215-220.
-
(1999)
Science
, vol.285
, pp. 215-220
-
-
Marsh, M.1
McMahon, H.T.2
-
67
-
-
84891841884
-
Multifaceted roles of GSK-3 and Wnt/β -catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
-
McCubrey JA, Steelman LS, Bertrand FE, Davis NM, Abrams SL, Montalto G, D'Assoro AB, Libra M, Nicoletti F, Maestro R, Basecke J, Cocco L, Cervello M, Martelli AM. 2014. Multifaceted roles of GSK-3 and Wnt/β -catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention. Leukemia 28:15-33.
-
(2014)
Leukemia
, vol.28
, pp. 15-33
-
-
McCubrey, J.A.1
Steelman, L.S.2
Bertrand, F.E.3
Davis, N.M.4
Abrams, S.L.5
Montalto, G.6
D'Assoro, A.B.7
Libra, M.8
Nicoletti, F.9
Maestro, R.10
Basecke, J.11
Cocco, L.12
Cervello, M.13
Martelli, A.M.14
-
68
-
-
79960720320
-
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
-
McMahon HT, Boucrot E. 2011. Molecular mechanism and physiological functions of clathrin-mediated endocytosis. Nat Rev Mol Cell Biol 12:517-533.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 517-533
-
-
McMahon, H.T.1
Boucrot, E.2
-
69
-
-
81355161240
-
Inhibition of GSK3 by Wnt signalling-two contrasting models
-
Metcalfe C, Bienz M. 2011. Inhibition of GSK3 by Wnt signalling-two contrasting models. J Cell Sci 124:3537-3544.
-
(2011)
J Cell Sci
, vol.124
, pp. 3537-3544
-
-
Metcalfe, C.1
Bienz, M.2
-
70
-
-
84871258791
-
High-affinity Dkk1 receptor Kremen1 is internalized by clathrin-mediated endocytosis
-
Mishra SK, Funair L, Cressley A, Gittes GK, Burns RC. 2012. High-affinity Dkk1 receptor Kremen1 is internalized by clathrin-mediated endocytosis. PLoS One 7:e52190.
-
(2012)
PLoS One
, vol.7
, pp. e52190
-
-
Mishra, S.K.1
Funair, L.2
Cressley, A.3
Gittes, G.K.4
Burns, R.C.5
-
72
-
-
77954903507
-
Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt
-
Mukai A, Yamamoto-Hino M, Awano W, Watanabe W, Komada M, Goto S. 2010. Balanced ubiquitylation and deubiquitylation of Frizzled regulate cellular responsiveness to Wg/Wnt. EMBO J 29:2114-2125.
-
(2010)
EMBO J
, vol.29
, pp. 2114-2125
-
-
Mukai, A.1
Yamamoto-Hino, M.2
Awano, W.3
Watanabe, W.4
Komada, M.5
Goto, S.6
-
73
-
-
33744964431
-
Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
-
Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK. 2006. Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem 281:13247-13257.
-
(2006)
J Biol Chem
, vol.281
, pp. 13247-13257
-
-
Nam, J.S.1
Turcotte, T.J.2
Smith, P.F.3
Choi, S.4
Yoon, J.K.5
-
74
-
-
0033180030
-
Head in the WNT: The molecular nature of Spemann's head organizer
-
Niehrs C. 1999. Head in the WNT: The molecular nature of Spemann's head organizer. Trends Genet 15:314-319.
-
(1999)
Trends Genet
, vol.15
, pp. 314-319
-
-
Niehrs, C.1
-
75
-
-
0033710390
-
Characterization of two fly LGR (leucine-rich repeat-containing, G protein-coupled receptor) proteins homologous to vertebrate glycoprotein hormone receptors: constitutive activation of wild-type fly LGR1 but not LGR2 in transfected mammalian cells
-
Nishi S, Hsu SY, Zell K, Hsueh AJ. 2000. Characterization of two fly LGR (leucine-rich repeat-containing, G protein-coupled receptor) proteins homologous to vertebrate glycoprotein hormone receptors: constitutive activation of wild-type fly LGR1 but not LGR2 in transfected mammalian cells. Endocrinology 141:4081-4090.
-
(2000)
Endocrinology
, vol.141
, pp. 4081-4090
-
-
Nishi, S.1
Hsu, S.Y.2
Zell, K.3
Hsueh, A.J.4
-
76
-
-
77954365864
-
Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization
-
Nishita M, Itsukushima S, Nomachi A, Endo M, Wang Z, Inaba D, Qiao S, Takada S, Kikuchi A, Minami Y. 2010. Ror2/Frizzled complex mediates Wnt5a-induced AP-1 activation by regulating Dishevelled polymerization. Mol Cell Biol 30:3610-3619.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3610-3619
-
-
Nishita, M.1
Itsukushima, S.2
Nomachi, A.3
Endo, M.4
Wang, Z.5
Inaba, D.6
Qiao, S.7
Takada, S.8
Kikuchi, A.9
Minami, Y.10
-
77
-
-
0030917251
-
A versatile transcriptional effector of Wingless signaling
-
Nusse R. 1997. A versatile transcriptional effector of Wingless signaling. Cell 89:321-323.
-
(1997)
Cell
, vol.89
, pp. 321-323
-
-
Nusse, R.1
-
79
-
-
68549133582
-
Wnt signaling and stem cell control
-
Nusse R, Fuerer C, Ching W, Harnish K, Logan C, Zeng A, ten Berge D, Kalani Y. 2008. Wnt signaling and stem cell control. Cold Spring Harb Symp Quant Biol 73:59-66.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 59-66
-
-
Nusse, R.1
Fuerer, C.2
Ching, W.3
Harnish, K.4
Logan, C.5
Zeng, A.6
ten Berge, D.7
Kalani, Y.8
-
80
-
-
79952491185
-
Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis
-
Ohkawara B, Glinka A, Niehrs C. 2011. Rspo3 binds syndecan 4 and induces Wnt/PCP signaling via clathrin-mediated endocytosis to promote morphogenesis. Dev Cell 20:303-314.
-
(2011)
Dev Cell
, vol.20
, pp. 303-314
-
-
Ohkawara, B.1
Glinka, A.2
Niehrs, C.3
-
81
-
-
84861581233
-
Exome sequencing of liver fluke-associated cholangiocarcinoma
-
Ong CK, Subimerb C, Pairojkul C, Wongkham S, Cutcutache I, Yu W, McPherson JR, Allen GE, Ng CC, Wong BH, Myint SS, Rajasegaran V, Heng HL, Gan A, Zang ZJ, Wu Y, Wu J, Lee MH, Huang D, Ong P, Chan-on W, Cao Y, Qian CN, Lim KH, Ooi A, Dykema K, Furge K, Kukongviriyapan V, Sripa B, Wongkham C, Yongvanit P, Futreal PA, Bhudhisawasdi V, Rozen S, Tan P, Teh BT. 2012. Exome sequencing of liver fluke-associated cholangiocarcinoma. Nat Genet 44:690-693.
-
(2012)
Nat Genet
, vol.44
, pp. 690-693
-
-
Ong, C.K.1
Subimerb, C.2
Pairojkul, C.3
Wongkham, S.4
Cutcutache, I.5
Yu, W.6
McPherson, J.R.7
Allen, G.E.8
Ng, C.C.9
Wong, B.H.10
Myint, S.S.11
Rajasegaran, V.12
Heng, H.L.13
Gan, A.14
Zang, Z.J.15
Wu, Y.16
Wu, J.17
Lee, M.H.18
Huang, D.19
Ong, P.20
Chan-on, W.21
Cao, Y.22
Qian, C.N.23
Lim, K.H.24
Ooi, A.25
Dykema, K.26
Furge, K.27
Kukongviriyapan, V.28
Sripa, B.29
Wongkham, C.30
Yongvanit, P.31
Futreal, P.A.32
Bhudhisawasdi, V.33
Rozen, S.34
Tan, P.35
Teh, B.T.36
more..
-
83
-
-
51149123490
-
Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation
-
Pan W, Choi SC, Wang H, Qin Y, Volpicelli-Daley L, Swan L, Lucast L, Khoo C, Zhang X, Li L, Abrams CS, Sokol SY, Wu D. 2008. Wnt3a-mediated formation of phosphatidylinositol 4, 5-bisphosphate regulates LRP6 phosphorylation. Science 321:1350-1353.
-
(2008)
Science
, vol.321
, pp. 1350-1353
-
-
Pan, W.1
Choi, S.C.2
Wang, H.3
Qin, Y.4
Volpicelli-Daley, L.5
Swan, L.6
Lucast, L.7
Khoo, C.8
Zhang, X.9
Li, L.10
Abrams, C.S.11
Sokol, S.Y.12
Wu, D.13
-
85
-
-
84892602873
-
Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling
-
Peng WC, de Lau W, Madoori PK, Forneris F, Granneman JC, Clevers H, Gros P. 2013. Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling. PLoS One 8:e83110.
-
(2013)
PLoS One
, vol.8
, pp. e83110
-
-
Peng, W.C.1
de Lau, W.2
Madoori, P.K.3
Forneris, F.4
Granneman, J.C.5
Clevers, H.6
Gros, P.7
-
86
-
-
58149185151
-
Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling
-
Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Lee SJ, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC. 2008. Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling. PLoS One 3:e4046.
-
(2008)
PLoS One
, vol.3
, pp. e4046
-
-
Piao, S.1
Lee, S.H.2
Kim, H.3
Yum, S.4
Stamos, J.L.5
Xu, Y.6
Lee, S.J.7
Lee, J.8
Oh, S.9
Han, J.K.10
Park, B.J.11
Weis, W.I.12
Ha, N.C.13
-
87
-
-
31144448719
-
Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs
-
Piddini E, Marshall F, Dubois L, Hirst E, Vincent JP. 2005. Arrow (LRP6) and Frizzled2 cooperate to degrade Wingless in Drosophila imaginal discs. Development 132:5479-5489.
-
(2005)
Development
, vol.132
, pp. 5479-5489
-
-
Piddini, E.1
Marshall, F.2
Dubois, L.3
Hirst, E.4
Vincent, J.P.5
-
89
-
-
0034727078
-
An LDL-receptor-related protein mediates Wnt signalling in mice
-
Pinson KI, Brennan J, Monkley S, Avery BJ, Skarnes WC. 2000. An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407:535-538.
-
(2000)
Nature
, vol.407
, pp. 535-538
-
-
Pinson, K.I.1
Brennan, J.2
Monkley, S.3
Avery, B.J.4
Skarnes, W.C.5
-
90
-
-
37749018903
-
Biogenesis and function of multivesicular bodies
-
Piper RC, Katzmann DJ. 2007. Biogenesis and function of multivesicular bodies. Annu Rev Cell Dev Biol 23:519-547.
-
(2007)
Annu Rev Cell Dev Biol
, vol.23
, pp. 519-547
-
-
Piper, R.C.1
Katzmann, D.J.2
-
91
-
-
0742288598
-
The dynamin superfamily: Universal membrane tubulation and fission molecules
-
Praefcke GJ, McMahon HT. 2004. The dynamin superfamily: Universal membrane tubulation and fission molecules. Nat Rev Mol Cell Biol 5:133-147.
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 133-147
-
-
Praefcke, G.J.1
McMahon, H.T.2
-
92
-
-
45349091779
-
Focusing on clathrin-mediated endocytosis
-
Rappoport JZ. 2008. Focusing on clathrin-mediated endocytosis. Biochem J 412:415-423.
-
(2008)
Biochem J
, vol.412
, pp. 415-423
-
-
Rappoport, J.Z.1
-
93
-
-
0030905162
-
A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors
-
Rattner A, Hsieh JC, Smallwood PM, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. 1997. A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci U S A 94:2859-2863.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 2859-2863
-
-
Rattner, A.1
Hsieh, J.C.2
Smallwood, P.M.3
Gilbert, D.J.4
Copeland, N.G.5
Jenkins, N.A.6
Nathans, J.7
-
94
-
-
0036123019
-
Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae
-
Razani B, Wang XB, Engelman JA, Battista M, Lagaud G, Zhang XL, Kneitz B, Hou H, Christ GJ, Edelmann W, Lisanti MP. 2002. Caveolin-2-deficient mice show evidence of severe pulmonary dysfunction without disruption of caveolae. Mol Cell Biol 22:2329-2344.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 2329-2344
-
-
Razani, B.1
Wang, X.B.2
Engelman, J.A.3
Battista, M.4
Lagaud, G.5
Zhang, X.L.6
Kneitz, B.7
Hou, H.8
Christ, G.J.9
Edelmann, W.10
Lisanti, M.P.11
-
95
-
-
0036733284
-
Caveolae: From cell biology to animal physiology
-
Razani B, Woodman SE, Lisanti MP. 2002b. Caveolae: From cell biology to animal physiology. Pharmacol Rev 54:431-467.
-
(2002)
Pharmacol Rev
, vol.54
, pp. 431-467
-
-
Razani, B.1
Woodman, S.E.2
Lisanti, M.P.3
-
96
-
-
17244376814
-
Wnt signalling in stem cells and cancer
-
Reya T, Clevers H. 2005. Wnt signalling in stem cells and cancer. Nature 434:843-850.
-
(2005)
Nature
, vol.434
, pp. 843-850
-
-
Reya, T.1
Clevers, H.2
-
97
-
-
33646047425
-
Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing
-
Rives AF, Rochlin KM, Wehrli M, Schwartz SL, DiNardo S. 2006. Endocytic trafficking of Wingless and its receptors, Arrow and DFrizzled-2, in the Drosophila wing. Dev Biol 293:268-283.
-
(2006)
Dev Biol
, vol.293
, pp. 268-283
-
-
Rives, A.F.1
Rochlin, K.M.2
Wehrli, M.3
Schwartz, S.L.4
DiNardo, S.5
-
98
-
-
84864012571
-
R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5
-
Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, Zietzling S, Beck V, Therier M, Isken A, Xie Y, Zhang Y, Hao H, Shi X, Liu D, Song Q, Clay I, Hintzen G, Tchorz J, Bouchez LC, Michaud G, Finan P, Myer VE, Bouwmeester T, Porter J, Hild M, Bassilana F, Parker CN, Cong F. 2012. R-Spondin potentiates Wnt/β-catenin signaling through orphan receptors LGR4 and LGR5. PLoS One 7:e40976.
-
(2012)
PLoS One
, vol.7
, pp. e40976
-
-
Ruffner, H.1
Sprunger, J.2
Charlat, O.3
Leighton-Davies, J.4
Grosshans, B.5
Salathe, A.6
Zietzling, S.7
Beck, V.8
Therier, M.9
Isken, A.10
Xie, Y.11
Zhang, Y.12
Hao, H.13
Shi, X.14
Liu, D.15
Song, Q.16
Clay, I.17
Hintzen, G.18
Tchorz, J.19
Bouchez, L.C.20
Michaud, G.21
Finan, P.22
Myer, V.E.23
Bouwmeester, T.24
Porter, J.25
Hild, M.26
Bassilana, F.27
Parker, C.N.28
Cong, F.29
more..
-
99
-
-
84872931911
-
RNF43 is a tumour suppressor gene mutated in mucinous tumours of the ovary
-
Ryland GL, Hunter SM, Doyle MA, Rowley SM, Christie M, Allan PE, Bowtell DD, Gorringe KL, Campbell IG, Group AOCS. 2013. RNF43 is a tumour suppressor gene mutated in mucinous tumours of the ovary. J Pathol 229:469-476.
-
(2013)
J Pathol
, vol.229
, pp. 469-476
-
-
Ryland, G.L.1
Hunter, S.M.2
Doyle, M.A.3
Rowley, S.M.4
Christie, M.5
Allan, P.E.6
Bowtell, D.D.7
Gorringe, K.L.8
Campbell, I.G.9
Group, A.O.C.S.10
-
100
-
-
76649119449
-
LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse
-
Sakane H, Yamamoto H, Kikuchi A. 2010. LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse. J Cell Sci 123:360-368.
-
(2010)
J Cell Sci
, vol.123
, pp. 360-368
-
-
Sakane, H.1
Yamamoto, H.2
Kikuchi, A.3
-
101
-
-
32344438588
-
Purification and properties of rabconnectin-3
-
Sakisaka T, Takai Y. 2005. Purification and properties of rabconnectin-3. Methods Enzymol 403:401-407.
-
(2005)
Methods Enzymol
, vol.403
, pp. 401-407
-
-
Sakisaka, T.1
Takai, Y.2
-
102
-
-
75649084593
-
Wnt5a regulates distinct signalling pathways by binding to Frizzled2
-
Sato A, Yamamoto H, Sakane H, Koyama H, Kikuchi A. 2010. Wnt5a regulates distinct signalling pathways by binding to Frizzled2. EMBO J 29:41-54.
-
(2010)
EMBO J
, vol.29
, pp. 41-54
-
-
Sato, A.1
Yamamoto, H.2
Sakane, H.3
Koyama, H.4
Kikuchi, A.5
-
103
-
-
78650150896
-
International Union of Basic and Clinical Pharmacology
-
The class Frizzled receptors.
-
Schulte G. 2010. International Union of Basic and Clinical Pharmacology. LXXX. The class Frizzled receptors. 62:632-667.
-
(2010)
LXXX
, vol.62
, pp. 632-667
-
-
Schulte, G.1
-
104
-
-
34748812548
-
The Frizzled family of unconventional G-protein-coupled receptors
-
Schulte G, Bryja V. 2007. The Frizzled family of unconventional G-protein-coupled receptors. Trends Pharmacol Sci 28:518-525.
-
(2007)
Trends Pharmacol Sci
, vol.28
, pp. 518-525
-
-
Schulte, G.1
Bryja, V.2
-
105
-
-
34249890531
-
The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization
-
Schwarz-Romond T, Fiedler M, Shibata N, Butler PJ, Kikuchi A, Higuchi Y, Bienz M. 2007a. The DIX domain of Dishevelled confers Wnt signaling by dynamic polymerization. Nat Struct Mol Biol 14:484-492.
-
(2007)
Nat Struct Mol Biol
, vol.14
, pp. 484-492
-
-
Schwarz-Romond, T.1
Fiedler, M.2
Shibata, N.3
Butler, P.J.4
Kikuchi, A.5
Higuchi, Y.6
Bienz, M.7
-
106
-
-
34547750005
-
Dynamic recruitment of axin by Dishevelled protein assemblies
-
Schwarz-Romond T, Metcalfe C, Bienz M. 2007b. Dynamic recruitment of axin by Dishevelled protein assemblies. J Cell Sci 120:2402-2412.
-
(2007)
J Cell Sci
, vol.120
, pp. 2402-2412
-
-
Schwarz-Romond, T.1
Metcalfe, C.2
Bienz, M.3
-
107
-
-
0035954281
-
Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6
-
Semënov MV, Tamai K, Brott BK, Kühl M, Sokol S, He X. 2001. Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6. Curr Biol 11:951-961.
-
(2001)
Curr Biol
, vol.11
, pp. 951-961
-
-
Semënov, M.V.1
Tamai, K.2
Brott, B.K.3
Kühl, M.4
Sokol, S.5
He, X.6
-
108
-
-
78049397293
-
Rabconnectin-3 is a functional regulator of mammalian Notch signaling
-
Sethi N, Yan Y, Quek D, Schupbach T, Kang Y. 2010. Rabconnectin-3 is a functional regulator of mammalian Notch signaling. J Biol Chem 285:34757-34764.
-
(2010)
J Biol Chem
, vol.285
, pp. 34757-34764
-
-
Sethi, N.1
Yan, Y.2
Quek, D.3
Schupbach, T.4
Kang, Y.5
-
109
-
-
33645732587
-
Internalization is required for proper Wingless signaling in Drosophila melanogaster
-
Seto ES, Bellen HJ. 2006. Internalization is required for proper Wingless signaling in Drosophila melanogaster. J Cell Biol 173:95-106.
-
(2006)
J Cell Biol
, vol.173
, pp. 95-106
-
-
Seto, E.S.1
Bellen, H.J.2
-
110
-
-
0036733578
-
Cholesterol, lipid rafts, and disease
-
Simons K, Ehehalt R. 2002. Cholesterol, lipid rafts, and disease. J Clin Invest 110:597-603.
-
(2002)
J Clin Invest
, vol.110
, pp. 597-603
-
-
Simons, K.1
Ehehalt, R.2
-
112
-
-
84893605383
-
The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment
-
Snyder JC, Rochelle LK, Barak LS, Caron MG. 2013. The stem cell-expressed receptor Lgr5 possesses canonical and functionally active molecular determinants critical to β-arrestin-2 recruitment. PLoS One 8:e84476.
-
(2013)
PLoS One
, vol.8
, pp. e84476
-
-
Snyder, J.C.1
Rochelle, L.K.2
Barak, L.S.3
Caron, M.G.4
-
113
-
-
84876209624
-
Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network
-
Snyder JC, Rochelle LK, Lyerly HK, Caron MG, Barak LS. 2013. Constitutive internalization of the leucine-rich G protein-coupled receptor-5 (LGR5) to the trans-Golgi network. J Biol Chem 288 15:10286-10297.
-
(2013)
J Biol Chem 288
, vol.15
, pp. 10286-10297
-
-
Snyder, J.C.1
Rochelle, L.K.2
Lyerly, H.K.3
Caron, M.G.4
Barak, L.S.5
-
114
-
-
69249137477
-
Endocytosis and signalling: Intertwining molecular networks
-
Sorkin A, von Zastrow M. 2009. Endocytosis and signalling: Intertwining molecular networks. Nat Rev Mol Cell Biol 10:609-622.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 609-622
-
-
Sorkin, A.1
von Zastrow, M.2
-
115
-
-
0034704824
-
Wingless gradient formation in the Drosophila wing
-
Strigini M, Cohen SM. 2000. Wingless gradient formation in the Drosophila wing. Curr Biol 10:293-300.
-
(2000)
Curr Biol
, vol.10
, pp. 293-300
-
-
Strigini, M.1
Cohen, S.M.2
-
116
-
-
0030917227
-
The role of RhoA in tissue polarity and Frizzled signalling
-
Strutt DI, Weber U, Mlodzik M. 1997. The role of RhoA in tissue polarity and Frizzled signalling. Nature 387:292-295.
-
(1997)
Nature
, vol.387
, pp. 292-295
-
-
Strutt, D.I.1
Weber, U.2
Mlodzik, M.3
-
117
-
-
78650484935
-
Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes
-
Taelman VF, Dobrowolski R, Plouhinec JL, Fuentealba LC, Vorwald PP, Gumper I, Sabatini DD, De Robertis EM. 2010. Wnt signaling requires sequestration of glycogen synthase kinase 3 inside multivesicular endosomes. Cell 143:1136-1148.
-
(2010)
Cell
, vol.143
, pp. 1136-1148
-
-
Taelman, V.F.1
Dobrowolski, R.2
Plouhinec, J.L.3
Fuentealba, L.C.4
Vorwald, P.P.5
Gumper, I.6
Sabatini, D.D.7
De Robertis, E.M.8
-
118
-
-
0034727104
-
LDL-receptor-related proteins in Wnt signal transduction
-
Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, Hess F, Saint-Jeannet JP, He X. 2000. LDL-receptor-related proteins in Wnt signal transduction. Nature 407:530-535.
-
(2000)
Nature
, vol.407
, pp. 530-535
-
-
Tamai, K.1
Semenov, M.2
Kato, Y.3
Spokony, R.4
Liu, C.5
Katsuyama, Y.6
Hess, F.7
Saint-Jeannet, J.P.8
He, X.9
-
119
-
-
1642564513
-
A mechanism for Wnt coreceptor activation
-
Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang Z, He X. 2004. A mechanism for Wnt coreceptor activation. Mol Cell 13:149-156.
-
(2004)
Mol Cell
, vol.13
, pp. 149-156
-
-
Tamai, K.1
Zeng, X.2
Liu, C.3
Zhang, X.4
Harada, Y.5
Chang, Z.6
He, X.7
-
120
-
-
79955009076
-
Amer1/WTX couples Wnt-induced formation of PtdIns(4,5
-
Tanneberger K, Pfister AS, Brauburger K, Schneikert J, Hadjihannas MV, Kriz V, Schulte G, Bryja V, Behrens J. 2011. Amer1/WTX couples Wnt-induced formation of PtdIns(4, 5. )P2 to LRP6 phosphorylation. EMBO J 30:1433-1443.
-
(2011)
)P2 to LRP6 phosphorylation. EMBO J
, vol.30
, pp. 1433-1443
-
-
Tanneberger, K.1
Pfister, A.S.2
Brauburger, K.3
Schneikert, J.4
Hadjihannas, M.V.5
Kriz, V.6
Schulte, G.7
Bryja, V.8
Behrens, J.9
-
121
-
-
3042762612
-
Adaptor protein complex 1 mediates the transport of lysosomal proteins from a Golgi-like organelle to peripheral vacuoles in the primitive eukaryote Giardia lamblia
-
Touz MC, Kulakova L, Nash TE. 2004. Adaptor protein complex 1 mediates the transport of lysosomal proteins from a Golgi-like organelle to peripheral vacuoles in the primitive eukaryote Giardia lamblia. Mol Biol Cell 15:3053-3060.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 3053-3060
-
-
Touz, M.C.1
Kulakova, L.2
Nash, T.E.3
-
122
-
-
69249135065
-
Tickets to ride: selecting cargo for clathrin-regulated internalization
-
Traub LM. 2009. Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol 10:583-596.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 583-596
-
-
Traub, L.M.1
-
123
-
-
84901393749
-
Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration
-
Tuttle AM, Hoffman TL, Schilling TF. 2014. Rabconnectin-3a regulates vesicle endocytosis and canonical Wnt signaling in zebrafish neural crest migration. PLoS Biol 12:e1001852.
-
(2014)
PLoS Biol
, vol.12
, pp. e1001852
-
-
Tuttle, A.M.1
Hoffman, T.L.2
Schilling, T.F.3
-
124
-
-
0024453493
-
Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication
-
van den Heuvel M, Nusse R, Johnston P, Lawrence PA. 1989. Distribution of the wingless gene product in Drosophila embryos: a protein involved in cell-cell communication. Cell 59:739-749.
-
(1989)
Cell
, vol.59
, pp. 739-749
-
-
van den Heuvel, M.1
Nusse, R.2
Johnston, P.3
Lawrence, P.A.4
-
125
-
-
84893725748
-
Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6
-
Vinyoles M, Del Valle-Pérez B, Curto J, Viñas-Castells R, Alba-Castellón L, García de Herreros A, Duñach M. 2014. Multivesicular GSK3 sequestration upon Wnt signaling is controlled by p120-catenin/cadherin interaction with LRP5/6. Mol Cell 53:444-457.
-
(2014)
Mol Cell
, vol.53
, pp. 444-457
-
-
Vinyoles, M.1
Del Valle-Pérez, B.2
Curto, J.3
Viñas-Castells, R.4
Alba-Castellón, L.5
García de Herreros, A.6
Duñach, M.7
-
126
-
-
27744535862
-
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity
-
Wallingford JB, Habas R. 2005. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development 132:4421-4436.
-
(2005)
Development
, vol.132
, pp. 4421-4436
-
-
Wallingford, J.B.1
Habas, R.2
-
127
-
-
0034727099
-
Arrow encodes an LDL-receptor-related protein essential for Wingless signalling
-
Wehrli M, Dougan ST, Caldwell K, O'Keefe L, Schwartz S, Vaizel-Ohayon D, Schejter E, Tomlinson A, DiNardo S. 2000. Arrow encodes an LDL-receptor-related protein essential for Wingless signalling. Nature 407:527-530.
-
(2000)
Nature
, vol.407
, pp. 527-530
-
-
Wehrli, M.1
Dougan, S.T.2
Caldwell, K.3
O'Keefe, L.4
Schwartz, S.5
Vaizel-Ohayon, D.6
Schejter, E.7
Tomlinson, A.8
DiNardo, S.9
-
128
-
-
34447526784
-
R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling
-
Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X. 2007. R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling. J Biol Chem 282:15903-15911.
-
(2007)
J Biol Chem
, vol.282
, pp. 15903-15911
-
-
Wei, Q.1
Yokota, C.2
Semenov, M.V.3
Doble, B.4
Woodgett, J.5
He, X.6
-
129
-
-
85027919816
-
PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling
-
Wieffer M, Cibrián Uhalte, Posor E, Otten Y, Branz C, Schütz K, Mössinger I, Schu J, Abdelilah-Seyfried P, Krauß S, Haucke M. 2013. PI4K2β/AP-1-based TGN-endosomal sorting regulates Wnt signaling. Curr Biol 23:2185-2190.
-
(2013)
Curr Biol
, vol.23
, pp. 2185-2190
-
-
Wieffer, M.1
Cibrián, U.2
Posor, E.3
Otten, Y.4
Branz, C.5
Schütz, K.6
Mössinger, I.7
Schu, J.8
Abdelilah-Seyfried, P.9
Krauß, S.10
Haucke, M.11
-
130
-
-
0037737726
-
Wnt proteins are lipid-modified and can act as stem cell growth factors
-
Willert K, Brown JD, Danenberg E, Duncan AW, Weissman IL, Reya T, Yates JR, Nusse R. 2003. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423:448-452.
-
(2003)
Nature
, vol.423
, pp. 448-452
-
-
Willert, K.1
Brown, J.D.2
Danenberg, E.3
Duncan, A.W.4
Weissman, I.L.5
Reya, T.6
Yates, J.R.7
Nusse, R.8
-
132
-
-
34247383616
-
Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis
-
Wolfe BL, Trejo J. 2007. Clathrin-dependent mechanisms of G protein-coupled receptor endocytosis. Traffic 8:462-470.
-
(2007)
Traffic
, vol.8
, pp. 462-470
-
-
Wolfe, B.L.1
Trejo, J.2
-
133
-
-
0344413477
-
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled
-
Wong HC, Bourdelas A, Krauss A, Lee HJ, Shao Y, Wu D, Mlodzik M, Shi DL, Zheng J. 2003. Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol Cell 12:1251-1260.
-
(2003)
Mol Cell
, vol.12
, pp. 1251-1260
-
-
Wong, H.C.1
Bourdelas, A.2
Krauss, A.3
Lee, H.J.4
Shao, Y.5
Wu, D.6
Mlodzik, M.7
Shi, D.L.8
Zheng, J.9
-
134
-
-
0037064033
-
Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade
-
Woodman SE, Park DS, Cohen AW, Cheung MW, Chandra M, Shirani J, Tang B, Jelicks LA, Kitsis RN, Christ GJ, Factor SM, Tanowitz HB, Lisanti MP. 2002. Caveolin-3 knock-out mice develop a progressive cardiomyopathy and show hyperactivation of the p42/44 MAPK cascade. J Biol Chem 277:38988-38997.
-
(2002)
J Biol Chem
, vol.277
, pp. 38988-38997
-
-
Woodman, S.E.1
Park, D.S.2
Cohen, A.W.3
Cheung, M.W.4
Chandra, M.5
Shirani, J.6
Tang, B.7
Jelicks, L.A.8
Kitsis, R.N.9
Christ, G.J.10
Factor, S.M.11
Tanowitz, H.B.12
Lisanti, M.P.13
-
135
-
-
62849125293
-
Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6
-
Wu G, Huang H, Garcia Abreu, He J. 2009. Inhibition of GSK3 phosphorylation of beta-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6. PLoS One 4:e4926.
-
(2009)
PLoS One
, vol.4
, pp. e4926
-
-
Wu, G.1
Huang, H.2
Garcia, A.3
He, J.4
-
136
-
-
0036830126
-
Ligand receptor interactions in the Wnt signaling pathway in Drosophila
-
Wu CH, Nusse R. 2002. Ligand receptor interactions in the Wnt signaling pathway in Drosophila. J Biol Chem 277:41762-41769.
-
(2002)
J Biol Chem
, vol.277
, pp. 41762-41769
-
-
Wu, C.H.1
Nusse, R.2
-
137
-
-
33746482870
-
Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin
-
Yamamoto H, Komekado H, Kikuchi A. 2006. Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of beta-catenin. Dev Cell 11:213-223.
-
(2006)
Dev Cell
, vol.11
, pp. 213-223
-
-
Yamamoto, H.1
Komekado, H.2
Kikuchi, A.3
-
138
-
-
46049089076
-
Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling
-
Yamamoto H, Sakane H, Michiue T, Kikuchi A. 2008. Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of beta-catenin signaling. Dev Cell 15:37-48.
-
(2008)
Dev Cell
, vol.15
, pp. 37-48
-
-
Yamamoto, H.1
Sakane, H.2
Michiue, T.3
Kikuchi, A.4
-
139
-
-
69949137273
-
The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila
-
Yan Y, Denef N, Schüpbach T. 2009. The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila. Dev Cell 17:387-402.
-
(2009)
Dev Cell
, vol.17
, pp. 387-402
-
-
Yan, Y.1
Denef, N.2
Schüpbach, T.3
-
140
-
-
84906824299
-
TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis
-
Yu S, Nie Y, Knowles B, Sakamori R, Stypulkowski E, Patel C, Das S, Douard V, Ferraris RP, Bonder EM, Goldenring JR, Ip YT, Gao N. 2014. TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J 33:1882-1895.
-
(2014)
EMBO J
, vol.33
, pp. 1882-1895
-
-
Yu, S.1
Nie, Y.2
Knowles, B.3
Sakamori, R.4
Stypulkowski, E.5
Patel, C.6
Das, S.7
Douard, V.8
Ferraris, R.P.9
Bonder, E.M.10
Goldenring, J.R.11
Ip, Y.T.12
Gao, N.13
-
141
-
-
33845875500
-
Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling
-
Yu A, Rual JF, Tamai K, Harada Y, Vidal M, He X, Kirchhausen T. 2007. Association of Dishevelled with the clathrin AP-2 adaptor is required for Frizzled endocytosis and planar cell polarity signaling. Dev Cell 12:129-141.
-
(2007)
Dev Cell
, vol.12
, pp. 129-141
-
-
Yu, A.1
Rual, J.F.2
Tamai, K.3
Harada, Y.4
Vidal, M.5
He, X.6
Kirchhausen, T.7
-
142
-
-
79958760196
-
Elevated inflammatory response in caveolin-1-deficient mice with Pseudomonas aeruginosa infection is mediated by STAT3 protein and nuclear factor kappaB (NF-kappaB)
-
Yuan K, Huang C, Fox J, Gaid M, Weaver A, Li G, Singh BB, Gao H, Wu M. 2011. Elevated inflammatory response in caveolin-1-deficient mice with Pseudomonas aeruginosa infection is mediated by STAT3 protein and nuclear factor kappaB (NF-kappaB). J Biol Chem 286 24:21814-21825.
-
(2011)
J Biol Chem 286
, vol.24
, pp. 21814-21825
-
-
Yuan, K.1
Huang, C.2
Fox, J.3
Gaid, M.4
Weaver, A.5
Li, G.6
Singh, B.B.7
Gao, H.8
Wu, M.9
-
143
-
-
38949194936
-
Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions
-
Zeng X, Huang H, Tamai K, Zhang X, Harada Y, Yokota C, Almeida K, Wang J, Doble B, Woodgett J, Wynshaw-Boris A, Hsieh JC, He X. 2008. Initiation of Wnt signaling: control of Wnt coreceptor Lrp6 phosphorylation/activation via frizzled, dishevelled and axin functions. Development 135:367-375.
-
(2008)
Development
, vol.135
, pp. 367-375
-
-
Zeng, X.1
Huang, H.2
Tamai, K.3
Zhang, X.4
Harada, Y.5
Yokota, C.6
Almeida, K.7
Wang, J.8
Doble, B.9
Woodgett, J.10
Wynshaw-Boris, A.11
Hsieh, J.C.12
He, X.13
-
144
-
-
28644439005
-
A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation
-
Zeng X, Tamai K, Doble B, Li S, Huang H, Habas R, Okamura H, Woodgett J, He X. 2005. A dual-kinase mechanism for Wnt co-receptor phosphorylation and activation. Nature 438:873-877.
-
(2005)
Nature
, vol.438
, pp. 873-877
-
-
Zeng, X.1
Tamai, K.2
Doble, B.3
Li, S.4
Huang, H.5
Habas, R.6
Okamura, H.7
Woodgett, J.8
He, X.9
-
145
-
-
84899044321
-
ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma
-
Zhou Y, Lan J, Wang W, Shi Q, Lan Y, Cheng Z, Guan H. 2013. ZNRF3 acts as a tumour suppressor by the Wnt signalling pathway in human gastric adenocarcinoma. J Mol Histol 44:555-563.
-
(2013)
J Mol Histol
, vol.44
, pp. 555-563
-
-
Zhou, Y.1
Lan, J.2
Wang, W.3
Shi, Q.4
Lan, Y.5
Cheng, Z.6
Guan, H.7
-
146
-
-
84883025477
-
Lypd6 enhances Wnt/Ö -catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains
-
Özhan G, Sezgin E, Wehner D, Pfister AS, Kühl SJ, Kagermeier-Schenk B, Kühl M, Schwille P, Weidinger G. 2013. Lypd6 enhances Wnt/Ö -catenin signaling by promoting Lrp6 phosphorylation in raft plasma membrane domains. Dev Cell 26:331-345.
-
(2013)
Dev Cell
, vol.26
, pp. 331-345
-
-
Özhan, G.1
Sezgin, E.2
Wehner, D.3
Pfister, A.S.4
Kühl, S.J.5
Kagermeier-Schenk, B.6
Kühl, M.7
Schwille, P.8
Weidinger, G.9
|