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Volumn 29, Issue 1, 2010, Pages 41-54

Wnt5a regulates distinct signalling pathways by binding to Frizzled2

Author keywords

catenin; Endocytosis; Frizzled2; Rac; Wnt5a

Indexed keywords

BETA CATENIN; CLATHRIN; FRIZZLED PROTEIN; FRIZZLED2 PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN 6; MESSENGER RNA; RAC PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT3A PROTEIN; WNT5A PROTEIN; CTNNB1 PROTEIN, HUMAN; FZD2 PROTEIN, HUMAN; G PROTEIN COUPLED RECEPTOR; LOW DENSITY LIPOPROTEIN RECEPTOR RELATED PROTEIN; LRP6 PROTEIN, HUMAN; ONCOPROTEIN; RECOMBINANT PROTEIN; WNT PROTEIN; WNT3 PROTEIN; WNT5A PROTEIN, HUMAN; WNT5A PROTEIN, MOUSE;

EID: 75649084593     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/emboj.2009.322     Document Type: Article
Times cited : (271)

References (50)
  • 3
    • 34147165527 scopus 로고    scopus 로고
    • Inhibition of endocytosis blocks Wnt signalling to β-catenin by promoting dishevelled degradation
    • Bryja V, Cajanek L, Grahn A, Schulte G (2007a) Inhibition of endocytosis blocks Wnt signalling to β-catenin by promoting dishevelled degradation. Acta Physiol (Oxf) 190: 55-61
    • (2007) Acta Physiol (Oxf) , vol.190 , pp. 55-61
    • Bryja, V.1    Cajanek, L.2    Grahn, A.3    Schulte, G.4
  • 4
    • 34249856025 scopus 로고    scopus 로고
    • β-arrestin is a necessary component of Wnt/b-catenin signaling in vitro and in vivo
    • Bryja V, Gradl D, Schambony A, Arenas E, Schulte G (2007b) β-arrestin is a necessary component of Wnt/b-catenin signaling in vitro and in vivo. Proc Natl Acad Sci USA 104: 6690-6695
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 6690-6695
    • Bryja, V.1    Gradl, D.2    Schambony, A.3    Arenas, E.4    Schulte, G.5
  • 5
    • 57049149000 scopus 로고    scopus 로고
    • β-Arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways
    • Bryja V, Schambony A, Cajanek L, Dominguez I, Arenas E, Schulte G (2008) β-Arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep 9: 1244-1250
    • (2008) EMBO Rep , vol.9 , pp. 1244-1250
    • Bryja, V.1    Schambony, A.2    Cajanek, L.3    Dominguez, I.4    Arenas, E.5    Schulte, G.6
  • 7
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD, Schmid SL (2003) Regulated portals of entry into the cell. Nature 422: 37-44
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 10
    • 33747339465 scopus 로고    scopus 로고
    • Wnt signaling: Multiple pathways, multiple receptors, and multiple transcription factors
    • Gordon MD, Nusse R (2006) Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factors. J Biol Chem 281: 22429-22433
    • (2006) J Biol Chem , vol.281 , pp. 22429-22433
    • Gordon, M.D.1    Nusse, R.2
  • 12
    • 0037439138 scopus 로고    scopus 로고
    • Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation
    • Habas R, Dawid IB, He X (2003) Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation. Genes Dev 17: 295-309
    • (2003) Genes Dev , vol.17 , pp. 295-309
    • Habas, R.1    Dawid, I.B.2    He, X.3
  • 13
    • 0030941498 scopus 로고    scopus 로고
    • A member of the Frizzled protein family mediating axis induction by Wnt-5A
    • He X, Saint-Jeannet JP, Wang Y, Nathans J, Dawid I, Varmus H (1997) A member of the Frizzled protein family mediating axis induction by Wnt-5A. Science 275: 1652-1654
    • (1997) Science , vol.275 , pp. 1652-1654
    • He, X.1    Saint-Jeannet, J.P.2    Wang, Y.3    Nathans, J.4    Dawid, I.5    Varmus, H.6
  • 14
    • 2342430345 scopus 로고    scopus 로고
    • LDL receptor-related proteins 5 and 6 in Wnt/b-catenin signaling: Arrows point the way
    • He X, Semënov M, Tamai K, Zeng X (2004) LDL receptor-related proteins 5 and 6 in Wnt/b-catenin signaling: arrows point the way. Development 131: 1663-1677
    • (2004) Development , vol.131 , pp. 1663-1677
    • He, X.1    Semënov, M.2    Tamai, K.3    Zeng, X.4
  • 17
    • 0035134328 scopus 로고    scopus 로고
    • Role of the ENTH domain in phosphatidylinositol-4,5bisphosphate binding and endocytosis
    • Itoh T, Koshiba S, Kigawa T, Kikuchi A, Yokoyama S, Takenawa T (2001) Role of the ENTH domain in phosphatidylinositol-4,5bisphosphate binding and endocytosis. Science 291: 1047-1051
    • (2001) Science , vol.291 , pp. 1047-1051
    • Itoh, T.1    Koshiba, S.2    Kigawa, T.3    Kikuchi, A.4    Yokoyama, S.5    Takenawa, T.6
  • 18
    • 0038783316 scopus 로고    scopus 로고
    • Secreted antagonists of the Wnt signalling pathway
    • Kawano Y, Kypta R (2003) Secreted antagonists of the Wnt signalling pathway. J Cell Sci 116: 2627-2634
    • (2003) J Cell Sci , vol.116 , pp. 2627-2634
    • Kawano, Y.1    Kypta, R.2
  • 19
    • 38949187882 scopus 로고    scopus 로고
    • Tumor formation due to abnormalities in the β-catenin-independent pathway of Wnt signaling
    • Kikuchi A, Yamamoto H (2008) Tumor formation due to abnormalities in the β-catenin-independent pathway of Wnt signaling. Cancer Sci 99: 202-208
    • (2008) Cancer Sci , vol.99 , pp. 202-208
    • Kikuchi, A.1    Yamamoto, H.2
  • 20
    • 61449249121 scopus 로고    scopus 로고
    • Selective activation mechanisms of Wnt signaling pathways
    • Kikuchi A, Yamamoto H, Sato A (2009) Selective activation mechanisms of Wnt signaling pathways. Trends Cell Biol 19: 119-129
    • (2009) Trends Cell Biol , vol.19 , pp. 119-129
    • Kikuchi, A.1    Yamamoto, H.2    Sato, A.3
  • 21
    • 34248995559 scopus 로고    scopus 로고
    • Essential role for β-arrestin 2 in the regulation of Xenopus convergent extension movements
    • Kim GH, Han JK (2007) Essential role for β-arrestin 2 in the regulation of Xenopus convergent extension movements. EMBO J 26: 2513-2526
    • (2007) EMBO J , vol.26 , pp. 2513-2526
    • Kim, G.H.1    Han, J.K.2
  • 22
    • 2942592798 scopus 로고    scopus 로고
    • Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase
    • Kishida S, Yamamoto H, Kikuchi A (2004) Wnt-3a and Dvl induce neurite retraction by activating Rho-associated kinase. Mol Cell Biol 24: 4487-4501
    • (2004) Mol Cell Biol , vol.24 , pp. 4487-4501
    • Kishida, S.1    Yamamoto, H.2    Kikuchi, A.3
  • 23
    • 33947213491 scopus 로고    scopus 로고
    • Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling
    • Kurayoshi M, Yamamoto H, Izumi S, Kikuchi A (2007) Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling. Biochem J 402: 515-523
    • (2007) Biochem J , vol.402 , pp. 515-523
    • Kurayoshi, M.1    Yamamoto, H.2    Izumi, S.3    Kikuchi, A.4
  • 24
    • 17644402459 scopus 로고    scopus 로고
    • Transduction of receptor signals by β-arrestins
    • Lefkowitz RJ, Shenoy SK (2005) Transduction of receptor signals by β-arrestins. Science 308: 512-517
    • (2005) Science , vol.308 , pp. 512-517
    • Lefkowitz, R.J.1    Shenoy, S.K.2
  • 25
    • 8444251784 scopus 로고    scopus 로고
    • The Wnt signaling pathway in development and disease
    • Logan CY, Nusse R (2004) The Wnt signaling pathway in development and disease. Annu Rev Cell Dev Biol 20: 781-810
    • (2004) Annu Rev Cell Dev Biol , vol.20 , pp. 781-810
    • Logan, C.Y.1    Nusse, R.2
  • 28
    • 33646241997 scopus 로고    scopus 로고
    • Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context
    • Mikels AJ, Nusse R (2006) Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context. PLoS Biol 4: 570-582
    • (2006) PLoS Biol , vol.4 , pp. 570-582
    • Mikels, A.J.1    Nusse, R.2
  • 30
    • 31144437395 scopus 로고    scopus 로고
    • Wnt3a links left-right determination with segmentation and anteroposterior axis elongation
    • Nakaya MA, Biris K, Tsukiyama T, Jaime S, Rawls JA, Yamaguchi TP (2005) Wnt3a links left-right determination with segmentation and anteroposterior axis elongation. Development 132: 5425-5436
    • (2005) Development , vol.132 , pp. 5425-5436
    • Nakaya, M.A.1    Biris, K.2    Tsukiyama, T.3    Jaime, S.4    Rawls, J.A.5    Yamaguchi, T.P.6
  • 34
    • 0036499130 scopus 로고    scopus 로고
    • Arresting developments in heptahelical receptor signaling and regulation
    • Perry SJ, Lefkowitz RJ (2002) Arresting developments in heptahelical receptor signaling and regulation. Trends Cell Biol 12: 130-138
    • (2002) Trends Cell Biol , vol.12 , pp. 130-138
    • Perry, S.J.1    Lefkowitz, R.J.2
  • 37
    • 84883840386 scopus 로고
    • Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines
    • Todaro GJ, Green H (1963) Quantitative studies of the growth of mouse embryo cells in culture and their development into established lines. J Cell Biol 17: 299-313
    • (1963) J Cell Biol , vol.17 , pp. 299-313
    • Todaro, G.J.1    Green, H.2
  • 38
    • 0043234811 scopus 로고    scopus 로고
    • Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent β-catenin degradation
    • Topol L, Jiang X, Choi H, Garrett-Beal L, Carolan PJ, Yang Y (2003) Wnt-5a inhibits the canonical Wnt pathway by promoting GSK-3-independent β-catenin degradation. J Cell Biol 162: 899-908
    • (2003) J Cell Biol , vol.162 , pp. 899-908
    • Topol, L.1    Jiang, X.2    Choi, H.3    Garrett-Beal, L.4    Carolan, P.J.5    Yang, Y.6
  • 39
    • 0029939701 scopus 로고    scopus 로고
    • Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development
    • Torres MA, Yang-Snyder JA, Purcell SM, DeMarais AA, McGrew LL, Moon RT (1996) Activities of the Wnt-1 class of secreted signaling factors are antagonized by the Wnt-5A class and by a dominant negative cadherin in early Xenopus development. J Cell Biol 133: 1123-1137
    • (1996) J Cell Biol , vol.133 , pp. 1123-1137
    • Torres, M.A.1    Yang-Snyder, J.A.2    Purcell, S.M.3    DeMarais, A.A.4    McGrew, L.L.5    Moon, R.T.6
  • 40
    • 0041695485 scopus 로고    scopus 로고
    • A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling
    • Veeman MT, Axelrod JD, Moon RT (2003) A second canon. Functions and mechanisms of β-catenin-independent Wnt signaling. Dev Cell 5: 367-377
    • (2003) Dev Cell , vol.5 , pp. 367-377
    • Veeman, M.T.1    Axelrod, J.D.2    Moon, R.T.3
  • 41
    • 33645096878 scopus 로고    scopus 로고
    • Structure-function analysis of Frizzleds
    • Wang HY, Liu T, Malbon CC (2006) Structure-function analysis of Frizzleds. Cell Signal 18: 934-941
    • (2006) Cell Signal , vol.18 , pp. 934-941
    • Wang, H.Y.1    Liu, T.2    Malbon, C.C.3
  • 43
    • 41949105179 scopus 로고    scopus 로고
    • Rac1 activation controls nuclear localization of β-catenin during canonical Wnt signaling
    • Wu X, Tu X, Joeng KS, Hilton MJ, Williams DA, Long F (2008) Rac1 activation controls nuclear localization of β-catenin during canonical Wnt signaling. Cell 133: 340-353
    • (2008) Cell , vol.133 , pp. 340-353
    • Wu, X.1    Tu, X.2    Joeng, K.S.3    Hilton, M.J.4    Williams, D.A.5    Long, F.6
  • 44
    • 0032938813 scopus 로고    scopus 로고
    • A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
    • Yamaguchi TP, Bradley A, McMahon AP, Jones S (1999) A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126: 1211-1223
    • (1999) Development , vol.126 , pp. 1211-1223
    • Yamaguchi, T.P.1    Bradley, A.2    McMahon, A.P.3    Jones, S.4
  • 45
    • 0031943002 scopus 로고    scopus 로고
    • Axil, a member of the Axin family, interacts with both glycogen synthase kinase-3b and β-catenin and inhibits axis formation of Xenopus embryos
    • Yamamoto H, Kishida S, Uochi T, Ikeda S, Koyama S, Asashima M, Kikuchi A (1998) Axil, a member of the Axin family, interacts with both glycogen synthase kinase-3b and β-catenin and inhibits axis formation of Xenopus embryos. Mol Cell Biol 18: 2867-2875
    • (1998) Mol Cell Biol , vol.18 , pp. 2867-2875
    • Yamamoto, H.1    Kishida, S.2    Uochi, T.3    Ikeda, S.4    Koyama, S.5    Asashima, M.6    Kikuchi, A.7
  • 46
    • 33746482870 scopus 로고    scopus 로고
    • Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin
    • Yamamoto H, Komekado H, Kikuchi A (2006) Caveolin is necessary for Wnt-3a-dependent internalization of LRP6 and accumulation of β-catenin. Dev Cell 11: 213-223
    • (2006) Dev Cell , vol.11 , pp. 213-223
    • Yamamoto, H.1    Komekado, H.2    Kikuchi, A.3
  • 47
    • 46049089076 scopus 로고    scopus 로고
    • Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling
    • Yamamoto H, Sakane H, Yamamoto H, Michiue T, Kikuchi A (2008) Wnt3a and Dkk1 regulate distinct internalization pathways of LRP6 to tune the activation of β-catenin signaling. Dev Cell 15: 37-48
    • (2008) Dev Cell , vol.15 , pp. 37-48
    • Yamamoto, H.1    Sakane, H.2    Yamamoto, H.3    Michiue, T.4    Kikuchi, A.5
  • 48
    • 33845875500 scopus 로고    scopus 로고
    • Association of dishevelled with the clathrin AP-2 adaptor is required for frizzled endocytosis and planar cell polarity signaling
    • Yu A, Rual JF, Tamai K, Harada Y, Vidal M, He X, Kirchhausen T (2007) Association of dishevelled with the clathrin AP-2 adaptor is required for frizzled endocytosis and planar cell polarity signaling. Dev Cell 12: 129-141
    • (2007) Dev Cell , vol.12 , pp. 129-141
    • Yu, A.1    Rual, J.F.2    Tamai, K.3    Harada, Y.4    Vidal, M.5    He, X.6    Kirchhausen, T.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.