Structures of Wnt-antagonist ZNRF3 and its complex with R-spondin 1 and implications for signaling

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Peng, Weng Chuan ^a   De Lau, Wim ^b   Madoori, Pramod K ^a   Forneris, Federico ^a   Granneman, Joke C M ^a   Clevers, Hans ^b   Gros, Piet ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GROWTH FACTOR; LEUCINE RICH REPEAT G PROTEIN COUPLED RECEPTOR 5; R SPONDIN 1; R SPONDIN 4; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ZINC RING FINGER 3 PROTEIN; DNA BINDING PROTEIN; LGR5 PROTEIN, HUMAN; LGR5 PROTEIN, MOUSE; MULTIPROTEIN COMPLEX; ONCOPROTEIN; RNF43 PROTEIN, HUMAN; RNF43 PROTEIN, MOUSE; RSPO1 PROTEIN, HUMAN; RSPO1 PROTEIN, MOUSE; THROMBOSPONDIN; UBIQUITIN PROTEIN LIGASE; ZINC AND RING FINGER 3 PROTEIN, HUMAN; ZINC AND RING FINGER 3 PROTEIN, MOUSE;

ANONYCHIA; ARTICLE; BINDING AFFINITY; BINDING COMPETITION; BINDING SITE; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE MUTATION; HUMAN; HUMAN CELL; LIGAND BINDING; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; ADULT STEM CELL; ANIMAL; CHEMISTRY; GENETICS; HEK293 CELL LINE; METABOLISM; MOUSE; PROTEIN QUATERNARY STRUCTURE; WNT SIGNALING PATHWAY; X RAY CRYSTALLOGRAPHY;

ADULT STEM CELLS; ANIMALS; CRYSTALLOGRAPHY, X-RAY; DNA-BINDING PROTEINS; HEK293 CELLS; HUMANS; MICE; MULTIPROTEIN COMPLEXES; ONCOGENE PROTEINS; PROTEIN STRUCTURE, QUATERNARY; RECEPTORS, G-PROTEIN-COUPLED; THROMBOSPONDINS; UBIQUITIN-PROTEIN LIGASES; WNT SIGNALING PATHWAY;

EID: 84892602873     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0083110     Document Type: Article

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