메뉴 건너뛰기




Volumn 126, Issue , 2015, Pages 631-648

Nanotechnological carriers for cancer chemotherapy: The state of the art

Author keywords

Anticancer drugs; Cancer; Dendrimers; Liposomes; Micelles; Nanoparticles

Indexed keywords

CHEMOTHERAPY; DENDRIMERS; DISEASE CONTROL; DISEASES; DRUG INTERACTIONS; LIPOSOMES; MICELLES; NANOPARTICLES;

EID: 84923065229     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2014.12.041     Document Type: Review
Times cited : (251)

References (269)
  • 2
    • 33748344520 scopus 로고    scopus 로고
    • Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery
    • Sinha R., Kim G.J., Nie S., Shin D.M. Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol. Cancer Ther. 2006, 5:1909-1917.
    • (2006) Mol. Cancer Ther. , vol.5 , pp. 1909-1917
    • Sinha, R.1    Kim, G.J.2    Nie, S.3    Shin, D.M.4
  • 3
    • 84455208546 scopus 로고    scopus 로고
    • Nanotecnology and cancer - an overview
    • Balaji S., Devi B.P. Nanotecnology and cancer - an overview. Int. J. Pharma BioSci. 2010, 1:186-201.
    • (2010) Int. J. Pharma BioSci. , vol.1 , pp. 186-201
    • Balaji, S.1    Devi, B.P.2
  • 4
    • 0028818455 scopus 로고
    • Physical (in) stability of liposomes upon chemical hydrolysis: the role of lysophospholipids and fatty acids
    • Zuidam N.J., Gouw H.K.M.E., Barenholz Y., Crommelin D.J.A. Physical (in) stability of liposomes upon chemical hydrolysis: the role of lysophospholipids and fatty acids. BBA: Biomembr. 1995, 1240:101-110.
    • (1995) BBA: Biomembr. , vol.1240 , pp. 101-110
    • Zuidam, N.J.1    Gouw, H.K.M.E.2    Barenholz, Y.3    Crommelin, D.J.A.4
  • 7
    • 84890442656 scopus 로고    scopus 로고
    • Available from: (accessed 27.02.14)
    • Chemotherapy Principles American Cancer Society 2013, Available from: http://www.cancer.org/treatment/treatmentsandsideeffects/treatmenttypes/chemotherapy/chemotherapyprinciplesanin-depthdiscussionofthetechniquesanditsroleintreatment/chemotherapy-principles-indepth-toc (accessed 27.02.14).
    • (2013) American Cancer Society
  • 8
    • 0003350858 scopus 로고    scopus 로고
    • Principles of cancer management: chemotherapy
    • Lippincott Williams & Wilkins Publishers, Philadelphia, V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.)
    • Chu E., Devita V.T. Principles of cancer management: chemotherapy. Cancer: Principles and Practice of Oncology 2001, 224-235. Lippincott Williams & Wilkins Publishers, Philadelphia. V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.).
    • (2001) Cancer: Principles and Practice of Oncology , pp. 224-235
    • Chu, E.1    Devita, V.T.2
  • 9
    • 84890442656 scopus 로고    scopus 로고
    • Available from: (accessed 26.02.14)
    • Different Types of Chemotherapy Drugs American Cancer Society 2013, Available from: http://www.cancer.org/treatmentsandsideeffects/treatmenttypes/chemotherapy/chemotherapyprinciplesanin-depthdiscussionofthetechniquesanditsroleintreatment/chemotherapy-principles-types-of-chemo-drugs (accessed 26.02.14).
    • (2013) American Cancer Society
  • 10
    • 0001768772 scopus 로고    scopus 로고
    • Antitumor alkylating agents
    • Lippincott Williams & Wilkins Publishers, Philadelphia, V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.)
    • Colvin O.M. Antitumor alkylating agents. Cancer: Principles and Practice of Oncology 2001, 278-288. Lippincott Williams & Wilkins Publishers, Philadelphia. V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.).
    • (2001) Cancer: Principles and Practice of Oncology , pp. 278-288
    • Colvin, O.M.1
  • 11
    • 0038278489 scopus 로고    scopus 로고
    • Antimetabolites
    • Lippincott Williams & Wilkins Publishers, Philadelphia, V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.)
    • Chu E., Mota A.C., Fogarasi M.C. Antimetabolites. Cancer: Principles and Practice of Oncology 2001, 298-317. Lippincott Williams & Wilkins Publishers, Philadelphia. V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.).
    • (2001) Cancer: Principles and Practice of Oncology , pp. 298-317
    • Chu, E.1    Mota, A.C.2    Fogarasi, M.C.3
  • 12
    • 0001273935 scopus 로고    scopus 로고
    • Topoisomerase interactive agents
    • Lippincott Williams & Wilkins Publishers, Philadelphia, V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.)
    • Stewart C.F., Ratain M.J. Topoisomerase interactive agents. Cancer: Principles and Practice of Oncology 2001, 318-328. Lippincott Williams & Wilkins Publishers, Philadelphia. V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.).
    • (2001) Cancer: Principles and Practice of Oncology , pp. 318-328
    • Stewart, C.F.1    Ratain, M.J.2
  • 13
    • 0000589775 scopus 로고    scopus 로고
    • Antimicrotubule agents
    • Lippincott Williams & Wilkins Publishers, Philadelphia, V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.)
    • Rowinsky E.K., Tolcher A.W. Antimicrotubule agents. Cancer: Principles and Practice of Oncology 2001, 329-344. Lippincott Williams & Wilkins Publishers, Philadelphia. V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.).
    • (2001) Cancer: Principles and Practice of Oncology , pp. 329-344
    • Rowinsky, E.K.1    Tolcher, A.W.2
  • 14
    • 11244279524 scopus 로고    scopus 로고
    • Miscellaneous chemotherapeutic agents
    • Lippincott Williams & Wilkins Publishers, Philadelphia, V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.)
    • Cheson B.D. Miscellaneous chemotherapeutic agents. Cancer: Principles and Practice of Oncology 2001, 345-350. Lippincott Williams & Wilkins Publishers, Philadelphia. V.T. Devita, S. Hellman, S.A. Rosenberg (Eds.).
    • (2001) Cancer: Principles and Practice of Oncology , pp. 345-350
    • Cheson, B.D.1
  • 15
    • 0018628646 scopus 로고
    • Disturbance of phospholipid metabolism during the selective destruction of tumor cells induced by alkyl-lysophospholipids
    • Modolell M., Andreesen R., Pahlke W., Brugger U., Munder P.G. Disturbance of phospholipid metabolism during the selective destruction of tumor cells induced by alkyl-lysophospholipids. Cancer Res. 1979, 39:4681-4686.
    • (1979) Cancer Res. , vol.39 , pp. 4681-4686
    • Modolell, M.1    Andreesen, R.2    Pahlke, W.3    Brugger, U.4    Munder, P.G.5
  • 16
    • 0022197382 scopus 로고
    • Changes in cellular lipid synthesis of normal and neoplastic cells during cytolysis induced by alkyl lysophospholipid analogues
    • Herrmann D.B.J. Changes in cellular lipid synthesis of normal and neoplastic cells during cytolysis induced by alkyl lysophospholipid analogues. J. Natl. Cancer Inst. 1985, 75:423-430.
    • (1985) J. Natl. Cancer Inst. , vol.75 , pp. 423-430
    • Herrmann, D.B.J.1
  • 18
    • 0031926037 scopus 로고    scopus 로고
    • Modification of tumor blood flow: current status and future directions
    • Chaplin D.J., Hill S.A., Bell K.M., Tozer G.M. Modification of tumor blood flow: current status and future directions. Semin. Radiat. Oncol. 1998, 8:151-163.
    • (1998) Semin. Radiat. Oncol. , vol.8 , pp. 151-163
    • Chaplin, D.J.1    Hill, S.A.2    Bell, K.M.3    Tozer, G.M.4
  • 19
    • 0035981024 scopus 로고    scopus 로고
    • The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors
    • Needham D., Dewhirst M.W. The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors. Adv. Drug Deliv. Rev. 2001, 53:285-305.
    • (2001) Adv. Drug Deliv. Rev. , vol.53 , pp. 285-305
    • Needham, D.1    Dewhirst, M.W.2
  • 20
    • 0028470454 scopus 로고
    • Barriers to drug delivery in solid tumors
    • Jain R.K. Barriers to drug delivery in solid tumors. Sci. Am. 1994, 271:58-65.
    • (1994) Sci. Am. , vol.271 , pp. 58-65
    • Jain, R.K.1
  • 21
    • 0031903379 scopus 로고    scopus 로고
    • Transvascular drug delivery in solid tumors
    • Yuan F. Transvascular drug delivery in solid tumors. Semin. Radiat. Oncol. 1998, 8:164-175.
    • (1998) Semin. Radiat. Oncol. , vol.8 , pp. 164-175
    • Yuan, F.1
  • 22
    • 0030055094 scopus 로고    scopus 로고
    • Current perspectives on camptothecins in cancer treatment
    • Dancey J., Eisenhauer E.A. Current perspectives on camptothecins in cancer treatment. Br. J. Cancer 1996, 74:327-338.
    • (1996) Br. J. Cancer , vol.74 , pp. 327-338
    • Dancey, J.1    Eisenhauer, E.A.2
  • 24
    • 0015378084 scopus 로고
    • Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): correlation with preclinical studies
    • Muggia F.M., Creaven P.J., Hansen H.H., Cohen M.H., Selawry O.S. Phase I clinical trial of weekly and daily treatment with camptothecin (NSC-100880): correlation with preclinical studies. Cancer Chemother. Rep. 1972, 56:515-521.
    • (1972) Cancer Chemother. Rep. , vol.56 , pp. 515-521
    • Muggia, F.M.1    Creaven, P.J.2    Hansen, H.H.3    Cohen, M.H.4    Selawry, O.S.5
  • 25
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • Matsumura Y., Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 1986, 46:6387-6392.
    • (1986) Cancer Res. , vol.46 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 26
    • 1242337285 scopus 로고    scopus 로고
    • Solubilizing excipients in oral and injectable formulations
    • Strickley R.G. Solubilizing excipients in oral and injectable formulations. Pharm. Res. 2004, 21:201-230.
    • (2004) Pharm. Res. , vol.21 , pp. 201-230
    • Strickley, R.G.1
  • 28
    • 0036100452 scopus 로고    scopus 로고
    • D-Methionine and cisplatin ototoxicity in the guinea pig: d-methionine influences cisplatin pharmacokinetics
    • Ekborn A., Laurell G., Johnström P., Wallin I., Eksborg S., Ehrsson H. d-Methionine and cisplatin ototoxicity in the guinea pig: d-methionine influences cisplatin pharmacokinetics. Hear. Res. 2002, 165:53-61.
    • (2002) Hear. Res. , vol.165 , pp. 53-61
    • Ekborn, A.1    Laurell, G.2    Johnström, P.3    Wallin, I.4    Eksborg, S.5    Ehrsson, H.6
  • 30
    • 84867559762 scopus 로고    scopus 로고
    • 5-Fluorouracil induced cardiotoxicity: review of the literature
    • Sorrentino M.F., Kim J., Foderaro A.E., Truesdell A.G. 5-Fluorouracil induced cardiotoxicity: review of the literature. Cardiol. J. 2012, 19:453-458.
    • (2012) Cardiol. J. , vol.19 , pp. 453-458
    • Sorrentino, M.F.1    Kim, J.2    Foderaro, A.E.3    Truesdell, A.G.4
  • 31
    • 0025326680 scopus 로고
    • Hypersensitivity reactions from taxol
    • Weiss R.B. Hypersensitivity reactions from taxol. J. Clin. Oncol. 1990, 8:1263-1268.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 1263-1268
    • Weiss, R.B.1
  • 32
    • 0033308953 scopus 로고    scopus 로고
    • Materials engineering of lipid bilayers for drug carrier performance
    • Needham D. Materials engineering of lipid bilayers for drug carrier performance. MRS Bull. 1999, 24:32-41.
    • (1999) MRS Bull. , vol.24 , pp. 32-41
    • Needham, D.1
  • 33
    • 0033046220 scopus 로고    scopus 로고
    • Mechanisms of phagocytosis in macrophages
    • Aderem A., Underhill D.M. Mechanisms of phagocytosis in macrophages. Annu. Rev. Immunol. 1999, 17:593-623.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 593-623
    • Aderem, A.1    Underhill, D.M.2
  • 34
    • 0014896886 scopus 로고
    • Physiology and physiopathology of the reticuloendothelial system
    • Saba T.M. Physiology and physiopathology of the reticuloendothelial system. Arch. Intern. Med. 1970, 126:1031-1052.
    • (1970) Arch. Intern. Med. , vol.126 , pp. 1031-1052
    • Saba, T.M.1
  • 35
    • 81355147743 scopus 로고    scopus 로고
    • Adaptive micro and nanoparticles: temporal control over carrier properties to facilitate drug delivery
    • Yoo J.W., Doshi N., Mitragotri S. Adaptive micro and nanoparticles: temporal control over carrier properties to facilitate drug delivery. Adv. Drug Deliv. Rev. 2011, 63:1247-1256.
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 1247-1256
    • Yoo, J.W.1    Doshi, N.2    Mitragotri, S.3
  • 36
    • 0034996764 scopus 로고    scopus 로고
    • Long-circulating and target-specific nanoparticles: theory to practice
    • Moghimi S.M., Hunter A.C., Murray J.C. Long-circulating and target-specific nanoparticles: theory to practice. Pharmacol. Rev. 2001, 53:283-318.
    • (2001) Pharmacol. Rev. , vol.53 , pp. 283-318
    • Moghimi, S.M.1    Hunter, A.C.2    Murray, J.C.3
  • 37
    • 1642575957 scopus 로고    scopus 로고
    • Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis
    • Rejman J., Oberle V., Zuhorn I.S., Hoekstra D. Size-dependent internalization of particles via the pathways of clathrin- and caveolae-mediated endocytosis. Biochem. J. 2004, 377:159-169.
    • (2004) Biochem. J. , vol.377 , pp. 159-169
    • Rejman, J.1    Oberle, V.2    Zuhorn, I.S.3    Hoekstra, D.4
  • 39
    • 57749207052 scopus 로고    scopus 로고
    • Intravascular delivery of particulate systems: does geometry really matter?
    • Decuzzi P., Pasqualini R., Arap W., Ferrari M. Intravascular delivery of particulate systems: does geometry really matter?. Pharm. Res. 2009, 26:235-243.
    • (2009) Pharm. Res. , vol.26 , pp. 235-243
    • Decuzzi, P.1    Pasqualini, R.2    Arap, W.3    Ferrari, M.4
  • 40
    • 77955607302 scopus 로고    scopus 로고
    • Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects
    • Yoo J.W., Chambers E., Mitragotri S. Factors that control the circulation time of nanoparticles in blood: challenges, solutions and future prospects. Curr. Pharm. Des. 2010, 16:2298-2307.
    • (2010) Curr. Pharm. Des. , vol.16 , pp. 2298-2307
    • Yoo, J.W.1    Chambers, E.2    Mitragotri, S.3
  • 41
    • 0032713936 scopus 로고    scopus 로고
    • Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial?
    • Hong R.L., Huang C.J., Tseng Y.L., Pang V.F., Chen S.T., Liu J.J., Chang F.H. Direct comparison of liposomal doxorubicin with or without polyethylene glycol coating in C-26 tumor-bearing mice: is surface coating with polyethylene glycol beneficial?. Clin. Cancer Res. 1999, 5:3645-3652.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 3645-3652
    • Hong, R.L.1    Huang, C.J.2    Tseng, Y.L.3    Pang, V.F.4    Chen, S.T.5    Liu, J.J.6    Chang, F.H.7
  • 43
    • 74349124409 scopus 로고    scopus 로고
    • Endocytosis and intracellular distribution of PLGA particles in endothelial cells: effect of particle geometry
    • Yoo J.W., Doshi N., Mitragotri S. Endocytosis and intracellular distribution of PLGA particles in endothelial cells: effect of particle geometry. Macromol. Rapid Commun. 2010, 31:142-148.
    • (2010) Macromol. Rapid Commun. , vol.31 , pp. 142-148
    • Yoo, J.W.1    Doshi, N.2    Mitragotri, S.3
  • 45
    • 0037084460 scopus 로고    scopus 로고
    • Fc-receptor-mediated phagocytosis is regulated by mechanical properties of the target
    • Beningo K.A., Wang Y.-L. Fc-receptor-mediated phagocytosis is regulated by mechanical properties of the target. J. Cell Sci. 2002, 115:849-856.
    • (2002) J. Cell Sci. , vol.115 , pp. 849-856
    • Beningo, K.A.1    Wang, Y.-L.2
  • 46
    • 79953054576 scopus 로고    scopus 로고
    • The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect
    • Fang J., Nakamura H., Maeda H. The EPR effect: unique features of tumor blood vessels for drug delivery, factors involved, and limitations and augmentation of the effect. Adv. Drug Deliv. Rev. 2011, 63:136-151.
    • (2011) Adv. Drug Deliv. Rev. , vol.63 , pp. 136-151
    • Fang, J.1    Nakamura, H.2    Maeda, H.3
  • 48
    • 40949127319 scopus 로고    scopus 로고
    • Therapeutic nanoparticles for drug delivery in cancer
    • Cho K., Wang X., Nie S., Chen Z.G., Shin D.M. Therapeutic nanoparticles for drug delivery in cancer. Clin. Cancer Res. 2008, 14:1310-1316.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 1310-1316
    • Cho, K.1    Wang, X.2    Nie, S.3    Chen, Z.G.4    Shin, D.M.5
  • 51
    • 84885087829 scopus 로고    scopus 로고
    • Novel colloidal carriers for psoriasis: current issues, mechanistic insight and novel delivery approaches
    • Pradhan M., Singh D., Singh M.R. Novel colloidal carriers for psoriasis: current issues, mechanistic insight and novel delivery approaches. J. Control. Release 2013, 170:380-395.
    • (2013) J. Control. Release , vol.170 , pp. 380-395
    • Pradhan, M.1    Singh, D.2    Singh, M.R.3
  • 52
    • 0030681273 scopus 로고    scopus 로고
    • Liposomes: opportunities in drug delivery
    • Allen T.M. Liposomes: opportunities in drug delivery. Drugs 1997, 54:8-14.
    • (1997) Drugs , vol.54 , pp. 8-14
    • Allen, T.M.1
  • 53
    • 0029070813 scopus 로고
    • Preparation and characterization of liposomes as therapeutic delivery systems: a review
    • Vemuri S., Rhodes C.T. Preparation and characterization of liposomes as therapeutic delivery systems: a review. Pharm. Acta Helv. 1995, 70:95-111.
    • (1995) Pharm. Acta Helv. , vol.70 , pp. 95-111
    • Vemuri, S.1    Rhodes, C.T.2
  • 54
    • 31544446865 scopus 로고    scopus 로고
    • Liposomes: an overview of manufacturing techniques
    • Mozafari R. Liposomes: an overview of manufacturing techniques. Cell. Mol. Biol. Lett. 2005, 10:711-719.
    • (2005) Cell. Mol. Biol. Lett. , vol.10 , pp. 711-719
    • Mozafari, R.1
  • 55
    • 1842843564 scopus 로고    scopus 로고
    • Liposomes produced in a pilot scale: production, purification and efficiency aspects
    • Wagner A., Vorauer-Uhl K., Katinger H. Liposomes produced in a pilot scale: production, purification and efficiency aspects. Eur. J. Pharm. Biopharm. 2002, 54:213-219.
    • (2002) Eur. J. Pharm. Biopharm. , vol.54 , pp. 213-219
    • Wagner, A.1    Vorauer-Uhl, K.2    Katinger, H.3
  • 56
    • 0033932547 scopus 로고    scopus 로고
    • Thermosensitive liposomes and localised hyperthermia - an effective bimodality approach for tumour management
    • Sandip B.T., Udupa N., Rao B.S.S., Devi P.U. Thermosensitive liposomes and localised hyperthermia - an effective bimodality approach for tumour management. Indian J. Pharmacol. 2000, 32:214-220.
    • (2000) Indian J. Pharmacol. , vol.32 , pp. 214-220
    • Sandip, B.T.1    Udupa, N.2    Rao, B.S.S.3    Devi, P.U.4
  • 57
    • 31344478508 scopus 로고    scopus 로고
    • Liposomes in analyses
    • Edwards K.A., Baeumner A.J. Liposomes in analyses. Talanta 2006, 68:1421-1431.
    • (2006) Talanta , vol.68 , pp. 1421-1431
    • Edwards, K.A.1    Baeumner, A.J.2
  • 58
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin V.P. Recent advances with liposomes as pharmaceutical carriers. Nat. Rev. Drug Discov. 2005, 4:145-160.
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 145-160
    • Torchilin, V.P.1
  • 59
    • 14644439267 scopus 로고    scopus 로고
    • Cancer nanotechnology: opportunities and challenges
    • Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat. Rev. Cancer 2005, 5:161-171.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 161-171
    • Ferrari, M.1
  • 60
    • 0036096806 scopus 로고    scopus 로고
    • Liposome-based drug delivery in breast cancer treatment
    • Park J. Liposome-based drug delivery in breast cancer treatment. Breast Cancer Res. 2002, 4:95-99.
    • (2002) Breast Cancer Res. , vol.4 , pp. 95-99
    • Park, J.1
  • 61
    • 49149083694 scopus 로고    scopus 로고
    • Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development
    • Drummond D.C., Noble C.O., Hayes M.E., Park J.W., Kirpotin D.B. Pharmacokinetics and in vivo drug release rates in liposomal nanocarrier development. J. Pharm. Sci. 2008, 97:4696-4740.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 4696-4740
    • Drummond, D.C.1    Noble, C.O.2    Hayes, M.E.3    Park, J.W.4    Kirpotin, D.B.5
  • 62
    • 84923052986 scopus 로고    scopus 로고
    • Development of innovative nanotechnology-based drug delivery systems for cancer therapy
    • Moutinho C., Matos C., Balcão V. Development of innovative nanotechnology-based drug delivery systems for cancer therapy. Revista FCS-UFP 2007, 4:94-104.
    • (2007) Revista FCS-UFP , vol.4 , pp. 94-104
    • Moutinho, C.1    Matos, C.2    Balcão, V.3
  • 65
    • 0027242138 scopus 로고
    • Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue
    • Wu N.Z., Da D., Rudoll T.L., Needham D., Whorton A.R., Dewhirst M.W. Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue. Cancer Res. 1993, 53:3765-3770.
    • (1993) Cancer Res. , vol.53 , pp. 3765-3770
    • Wu, N.Z.1    Da, D.2    Rudoll, T.L.3    Needham, D.4    Whorton, A.R.5    Dewhirst, M.W.6
  • 66
    • 0035120280 scopus 로고    scopus 로고
    • Stealth liposomes and tumor targeting: one step further in the quest for the magic bullet
    • Gabizon A.A. Stealth liposomes and tumor targeting: one step further in the quest for the magic bullet. Clin. Cancer Res. 2001, 7:223-225.
    • (2001) Clin. Cancer Res. , vol.7 , pp. 223-225
    • Gabizon, A.A.1
  • 67
    • 0942277118 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin in the treatment of breast cancer
    • O'Shaughnessy J.A. Pegylated liposomal doxorubicin in the treatment of breast cancer. Clin. Breast Cancer 2003, 4:318-328.
    • (2003) Clin. Breast Cancer , vol.4 , pp. 318-328
    • O'Shaughnessy, J.A.1
  • 68
    • 0035005359 scopus 로고    scopus 로고
    • Pegylated liposomal doxorubicin: metamorphosis of an old drug into a new form of chemotherapy
    • Gabizon A.A. Pegylated liposomal doxorubicin: metamorphosis of an old drug into a new form of chemotherapy. Cancer Invest. 2001, 19:424-436.
    • (2001) Cancer Invest. , vol.19 , pp. 424-436
    • Gabizon, A.A.1
  • 69
    • 0026742081 scopus 로고
    • Targeted accumulation of polyethylene glycol-coated immunoliposomes in infarcted rabbit myocardium
    • Torchilin V.P., Klibanov A.L., Huang L., O'Donnell S., Nossiff N.D., Khaw B.A. Targeted accumulation of polyethylene glycol-coated immunoliposomes in infarcted rabbit myocardium. FASEB J. 1992, 6:2716-2719.
    • (1992) FASEB J. , vol.6 , pp. 2716-2719
    • Torchilin, V.P.1    Klibanov, A.L.2    Huang, L.3    O'Donnell, S.4    Nossiff, N.D.5    Khaw, B.A.6
  • 70
    • 0028099635 scopus 로고
    • Immunoliposomes and PEGylated immunoliposomes: possible use for targeted delivery of imaging agents
    • Torchilin V.P. Immunoliposomes and PEGylated immunoliposomes: possible use for targeted delivery of imaging agents. ImmunoMethods 1994, 4:244-258.
    • (1994) ImmunoMethods , vol.4 , pp. 244-258
    • Torchilin, V.P.1
  • 71
    • 0030038867 scopus 로고    scopus 로고
    • Poly(ethylene glycol)-coated anti-cardiac myosin immunoliposomes: factors influencing targeted accumulation in the infarcted myocardium
    • Torchilin V.P., Narula J., Halpern E., Khaw B.A. Poly(ethylene glycol)-coated anti-cardiac myosin immunoliposomes: factors influencing targeted accumulation in the infarcted myocardium. BBA: Biomembr. 1996, 1279:75-83.
    • (1996) BBA: Biomembr. , vol.1279 , pp. 75-83
    • Torchilin, V.P.1    Narula, J.2    Halpern, E.3    Khaw, B.A.4
  • 72
    • 0018250922 scopus 로고
    • Design of liposomes for enhanced local release of drugs by hyperthermia
    • Yatvin M.B., Weinstein J.N., Dennis W.H., Blumenthal R. Design of liposomes for enhanced local release of drugs by hyperthermia. Science 1978, 202:1290-1293.
    • (1978) Science , vol.202 , pp. 1290-1293
    • Yatvin, M.B.1    Weinstein, J.N.2    Dennis, W.H.3    Blumenthal, R.4
  • 73
    • 0034671219 scopus 로고    scopus 로고
    • Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release
    • Kong G., Anyarambhatla G., Petros W.P., Braun R.D., Colvin O.M., Needham D., Dewhirst M.W. Efficacy of liposomes and hyperthermia in a human tumor xenograft model: importance of triggered drug release. Cancer Res. 2000, 60:6950-6957.
    • (2000) Cancer Res. , vol.60 , pp. 6950-6957
    • Kong, G.1    Anyarambhatla, G.2    Petros, W.P.3    Braun, R.D.4    Colvin, O.M.5    Needham, D.6    Dewhirst, M.W.7
  • 75
    • 61349107152 scopus 로고    scopus 로고
    • Targeted delivery of methotrexate to skeletal muscular tissue by thermosensitive magnetoliposomes
    • Zhu L., Huo Z., Wang L., Tong X., Xiao Y., Ni K. Targeted delivery of methotrexate to skeletal muscular tissue by thermosensitive magnetoliposomes. Int. J. Pharm. 2009, 370:136-143.
    • (2009) Int. J. Pharm. , vol.370 , pp. 136-143
    • Zhu, L.1    Huo, Z.2    Wang, L.3    Tong, X.4    Xiao, Y.5    Ni, K.6
  • 76
    • 84873266331 scopus 로고    scopus 로고
    • Immunoconjugates and long circulating systems: origins, current state of the art and future directions
    • Koshkaryev A., Sawant R., Deshpande M., Torchilin V. Immunoconjugates and long circulating systems: origins, current state of the art and future directions. Adv. Drug Deliv. Rev. 2013, 65:24-35.
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 24-35
    • Koshkaryev, A.1    Sawant, R.2    Deshpande, M.3    Torchilin, V.4
  • 77
    • 58149325630 scopus 로고
    • Non-ionic surfactant vesicles (niosomes): physical and pharmaceutical chemistry
    • Uchegbu I.F., Florence A.T. Non-ionic surfactant vesicles (niosomes): physical and pharmaceutical chemistry. Adv. Colloid Interface Sci. 1995, 58:1-55.
    • (1995) Adv. Colloid Interface Sci. , vol.58 , pp. 1-55
    • Uchegbu, I.F.1    Florence, A.T.2
  • 78
    • 2442651205 scopus 로고    scopus 로고
    • Effect of β-sitosterol on the characteristics of vesicular gels containing chlorhexidine
    • Farkas E., Schubert R., Zelkó R. Effect of β-sitosterol on the characteristics of vesicular gels containing chlorhexidine. Int. J. Pharm. 2004, 278:63-70.
    • (2004) Int. J. Pharm. , vol.278 , pp. 63-70
    • Farkas, E.1    Schubert, R.2    Zelkó, R.3
  • 80
    • 55749086377 scopus 로고    scopus 로고
    • Polyoxyethylated nonionic surfactants and their applications in topical ocular drug delivery
    • Jiao J. Polyoxyethylated nonionic surfactants and their applications in topical ocular drug delivery. Adv. Drug Deliv. Rev. 2008, 60:1663-1673.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 1663-1673
    • Jiao, J.1
  • 81
    • 84866430465 scopus 로고    scopus 로고
    • Nonionic surfactant vesicular systems for effective drug delivery - an overview
    • Kumar G.P., Rajeshwarrao P. Nonionic surfactant vesicular systems for effective drug delivery - an overview. Acta Pharm. Sin. B 2011, 1:208-219.
    • (2011) Acta Pharm. Sin. B , vol.1 , pp. 208-219
    • Kumar, G.P.1    Rajeshwarrao, P.2
  • 82
    • 84874397949 scopus 로고    scopus 로고
    • Construction of hyaluronic acid noisome as functional transdermal nanocarrier for tumor therapy
    • Kong M., Park H., Feng C., Hou L., Cheng X., Chen X. Construction of hyaluronic acid noisome as functional transdermal nanocarrier for tumor therapy. Carbohydr. Polym. 2013, 94:634-641.
    • (2013) Carbohydr. Polym. , vol.94 , pp. 634-641
    • Kong, M.1    Park, H.2    Feng, C.3    Hou, L.4    Cheng, X.5    Chen, X.6
  • 84
    • 0026508985 scopus 로고
    • Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force
    • Cevc G., Blume G. Lipid vesicles penetrate into intact skin owing to the transdermal osmotic gradients and hydration force. BBA: Biomembr. 1992, 1104:226-232.
    • (1992) BBA: Biomembr. , vol.1104 , pp. 226-232
    • Cevc, G.1    Blume, G.2
  • 86
    • 0345761185 scopus 로고    scopus 로고
    • Deformable liposomes for dermal administration of methotrexate
    • Trotta M., Peira E., Carlotti M.E., Gallarate M. Deformable liposomes for dermal administration of methotrexate. Int. J. Pharm. 2004, 270:119-125.
    • (2004) Int. J. Pharm. , vol.270 , pp. 119-125
    • Trotta, M.1    Peira, E.2    Carlotti, M.E.3    Gallarate, M.4
  • 87
    • 0033951387 scopus 로고    scopus 로고
    • Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration
    • El Maghraby G.M.M., Williams A.C., Barry B.W. Oestradiol skin delivery from ultradeformable liposomes: refinement of surfactant concentration. Int. J. Pharm. 2000, 196:63-74.
    • (2000) Int. J. Pharm. , vol.196 , pp. 63-74
    • El Maghraby, G.M.M.1    Williams, A.C.2    Barry, B.W.3
  • 88
    • 0030470587 scopus 로고    scopus 로고
    • Transfersomes, liposomes and other lipid suspensions on the skin: permeation enhancement, vesicle penetration, and transdermal drug delivery
    • Cevc G. Transfersomes, liposomes and other lipid suspensions on the skin: permeation enhancement, vesicle penetration, and transdermal drug delivery. Crit. Rev. Ther. Drug Carrier Syst. 1996, 13:257-388.
    • (1996) Crit. Rev. Ther. Drug Carrier Syst. , vol.13 , pp. 257-388
    • Cevc, G.1
  • 89
    • 0032735026 scopus 로고    scopus 로고
    • Skin delivery of oestradiol from deformable and traditional liposomes: mechanistic studies
    • El Maghraby G.M.M., Williams A.C., Barry B.W. Skin delivery of oestradiol from deformable and traditional liposomes: mechanistic studies. J. Pharm. Pharmacol. 1999, 51:1123-1134.
    • (1999) J. Pharm. Pharmacol. , vol.51 , pp. 1123-1134
    • El Maghraby, G.M.M.1    Williams, A.C.2    Barry, B.W.3
  • 90
    • 0037136041 scopus 로고    scopus 로고
    • Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements
    • Cevc G., Schätzlein A., Richardsen H. Ultradeformable lipid vesicles can penetrate the skin and other semi-permeable barriers unfragmented. Evidence from double label CLSM experiments and direct size measurements. BBA: Biomembr. 2002, 1564:21-30.
    • (2002) BBA: Biomembr. , vol.1564 , pp. 21-30
    • Cevc, G.1    Schätzlein, A.2    Richardsen, H.3
  • 91
    • 0242381937 scopus 로고    scopus 로고
    • Entrapment of bleomycin in ultra-deformable liposomes
    • Lau K.G., Chopra S., Maitani Y. Entrapment of bleomycin in ultra-deformable liposomes. STP Pharma Sci. 2003, 13:237-239.
    • (2003) STP Pharma Sci. , vol.13 , pp. 237-239
    • Lau, K.G.1    Chopra, S.2    Maitani, Y.3
  • 92
    • 23444450923 scopus 로고    scopus 로고
    • Ultra-deformable liposomes containing bleomycin: in vitro stability and toxicity on human cutaneous keratinocyte cell lines
    • Lau K.G., Hattori Y., Chopra S., O'Toole E.A., Storey A., Nagai T., Maitani Y. Ultra-deformable liposomes containing bleomycin: in vitro stability and toxicity on human cutaneous keratinocyte cell lines. Int. J. Pharma 2005, 300:4-12.
    • (2005) Int. J. Pharma , vol.300 , pp. 4-12
    • Lau, K.G.1    Hattori, Y.2    Chopra, S.3    O'Toole, E.A.4    Storey, A.5    Nagai, T.6    Maitani, Y.7
  • 93
    • 0034863372 scopus 로고    scopus 로고
    • Skin delivery of 5-fluorouracil from ultradeformable and standard liposomes in-vitro
    • El Maghraby G.M.M., Williams A.C., Barry B.W. Skin delivery of 5-fluorouracil from ultradeformable and standard liposomes in-vitro. J. Pharm. Pharmacol. 2001, 53:1069-1077.
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 1069-1077
    • El Maghraby, G.M.M.1    Williams, A.C.2    Barry, B.W.3
  • 94
    • 33745261719 scopus 로고    scopus 로고
    • Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin
    • Hiruta Y., Hattori Y., Kawano K., Obata Y., Maitani Y. Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin. J. Control. Release 2006, 113:146-154.
    • (2006) J. Control. Release , vol.113 , pp. 146-154
    • Hiruta, Y.1    Hattori, Y.2    Kawano, K.3    Obata, Y.4    Maitani, Y.5
  • 96
    • 0002915970 scopus 로고
    • Alcohols
    • CRC Press, Boca Raton, E.W. Smith, H.I. Maibach (Eds.)
    • Berner B., Liu P. Alcohols. Percutaneous Penetration Enhancers 1995, 45-60. CRC Press, Boca Raton. E.W. Smith, H.I. Maibach (Eds.).
    • (1995) Percutaneous Penetration Enhancers , pp. 45-60
    • Berner, B.1    Liu, P.2
  • 98
    • 0035479095 scopus 로고    scopus 로고
    • Is transdermal drug delivery research still important today?
    • Barry B.W. Is transdermal drug delivery research still important today?. Drug Discov. Today 2001, 6:967-971.
    • (2001) Drug Discov. Today , vol.6 , pp. 967-971
    • Barry, B.W.1
  • 100
    • 57849099131 scopus 로고    scopus 로고
    • Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
    • Pardeike J., Hommoss A., Müller R.H. Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int. J. Pharm. 2009, 366:170-184.
    • (2009) Int. J. Pharm. , vol.366 , pp. 170-184
    • Pardeike, J.1    Hommoss, A.2    Müller, R.H.3
  • 101
    • 0038032150 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art
    • Müller R.H., Mäder K., Gohla S. Solid lipid nanoparticles (SLN) for controlled drug delivery - a review of the state of the art. Eur. J. Pharm. Biopharm. 2000, 50:161-177.
    • (2000) Eur. J. Pharm. Biopharm. , vol.50 , pp. 161-177
    • Müller, R.H.1    Mäder, K.2    Gohla, S.3
  • 102
    • 84922998118 scopus 로고
    • (Inventors), Medication Vehicles Made of Solid Lipid Particles (Solid Lipid Nanospheres SLN)
    • J.S. Lucks, R.H. Müller (Inventors), Medication Vehicles Made of Solid Lipid Particles (Solid Lipid Nanospheres SLN), 1991.
    • (1991)
    • Lucks, J.S.1    Müller, R.H.2
  • 104
    • 34250893864 scopus 로고    scopus 로고
    • Cetyl palmitate-based NLC for topical delivery of Coenzyme Q10 - development, physicochemical characterization and in vitro release studies
    • Teeranachaideekul V., Souto E.B., Junyaprasert V.B., Müller R.H. Cetyl palmitate-based NLC for topical delivery of Coenzyme Q10 - development, physicochemical characterization and in vitro release studies. Eur. J. Pharm. Biopharm. 2007, 67:141-148.
    • (2007) Eur. J. Pharm. Biopharm. , vol.67 , pp. 141-148
    • Teeranachaideekul, V.1    Souto, E.B.2    Junyaprasert, V.B.3    Müller, R.H.4
  • 105
    • 2242472082 scopus 로고    scopus 로고
    • Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations
    • Müller R.H., Radtke M., Wissing S.A. Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations. Adv. Drug Deliv. Rev. 2002, 54:S131-S155.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. S131-S155
    • Müller, R.H.1    Radtke, M.2    Wissing, S.A.3
  • 106
    • 2442712381 scopus 로고    scopus 로고
    • Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery
    • Souto E.B., Wissing S.A., Barbosa C.M., Müller R.H. Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery. Int. J. Pharm. 2004, 278:71-77.
    • (2004) Int. J. Pharm. , vol.278 , pp. 71-77
    • Souto, E.B.1    Wissing, S.A.2    Barbosa, C.M.3    Müller, R.H.4
  • 107
    • 0033805858 scopus 로고    scopus 로고
    • Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems
    • Pouton C.W. Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems. Eur. J. Pharm. Sci. 2000, 11:S93-S98.
    • (2000) Eur. J. Pharm. Sci. , vol.11 , pp. S93-S98
    • Pouton, C.W.1
  • 108
    • 1242338847 scopus 로고    scopus 로고
    • Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy
    • Jores K., Mehnert W., Drechsler M., Bunjes H., Johann C., Mäder K. Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy. J. Control. Release 2004, 95:217-227.
    • (2004) J. Control. Release , vol.95 , pp. 217-227
    • Jores, K.1    Mehnert, W.2    Drechsler, M.3    Bunjes, H.4    Johann, C.5    Mäder, K.6
  • 109
    • 0342615073 scopus 로고    scopus 로고
    • Investigation on the viscoelastic properties of lipid based colloidal drug carriers
    • Lippacher A., Müller R.H., Mäder K. Investigation on the viscoelastic properties of lipid based colloidal drug carriers. Int. J. Pharm. 2000, 196:227-230.
    • (2000) Int. J. Pharm. , vol.196 , pp. 227-230
    • Lippacher, A.1    Müller, R.H.2    Mäder, K.3
  • 110
    • 84897071105 scopus 로고    scopus 로고
    • Etoposide loaded solid lipid nanoparticles for curtailing B16F10 melanoma colonization in lung
    • Athawale R.B., Jain D.S., Singh K.K., Gude R.P. Etoposide loaded solid lipid nanoparticles for curtailing B16F10 melanoma colonization in lung. Biomed. Pharmacother. 2014, 68:231-240.
    • (2014) Biomed. Pharmacother. , vol.68 , pp. 231-240
    • Athawale, R.B.1    Jain, D.S.2    Singh, K.K.3    Gude, R.P.4
  • 111
    • 84885181617 scopus 로고    scopus 로고
    • The formulation and delivery of curcumin with solid lipid nanoparticles for the treatment of on non-small cell lung cancer both in vitro and in vivo
    • Wang P., Zhang L., Peng H., Li Y., Xiong J., Xu Z. The formulation and delivery of curcumin with solid lipid nanoparticles for the treatment of on non-small cell lung cancer both in vitro and in vivo. Mater. Sci. Eng. C: Mater. Biol. Appl. 2013, 33:4802-4808.
    • (2013) Mater. Sci. Eng. C: Mater. Biol. Appl. , vol.33 , pp. 4802-4808
    • Wang, P.1    Zhang, L.2    Peng, H.3    Li, Y.4    Xiong, J.5    Xu, Z.6
  • 114
    • 84878380072 scopus 로고    scopus 로고
    • Drug resistance reversal activity of anticancer drug loaded solid lipid nanoparticles in multi-drug resistant cancer cells
    • Miao J., Du Y.-Z., Yuan H., Zhang X.-G., Hu F.-Q. Drug resistance reversal activity of anticancer drug loaded solid lipid nanoparticles in multi-drug resistant cancer cells. Colloids Surf. B: Biointerfaces 2013, 110:74-80.
    • (2013) Colloids Surf. B: Biointerfaces , vol.110 , pp. 74-80
    • Miao, J.1    Du, Y.-Z.2    Yuan, H.3    Zhang, X.-G.4    Hu, F.-Q.5
  • 115
    • 84878216928 scopus 로고    scopus 로고
    • Hyaluronic acid-coated nanostructured lipid carriers for targeting paclitaxel to cancer
    • Yang X.-Y., Li Y.-X., Li M., Zhang L., Feng L.-X., Zhang N. Hyaluronic acid-coated nanostructured lipid carriers for targeting paclitaxel to cancer. Cancer Lett. 2013, 334:338-345.
    • (2013) Cancer Lett. , vol.334 , pp. 338-345
    • Yang, X.-Y.1    Li, Y.-X.2    Li, M.3    Zhang, L.4    Feng, L.-X.5    Zhang, N.6
  • 116
    • 84892675615 scopus 로고    scopus 로고
    • Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA
    • Taratula O., Kuzmov A., Shah M., Garbuzenko O.B., Minko T. Nanostructured lipid carriers as multifunctional nanomedicine platform for pulmonary co-delivery of anticancer drugs and siRNA. J. Control. Release 2013, 171:349-357.
    • (2013) J. Control. Release , vol.171 , pp. 349-357
    • Taratula, O.1    Kuzmov, A.2    Shah, M.3    Garbuzenko, O.B.4    Minko, T.5
  • 117
    • 67649229657 scopus 로고    scopus 로고
    • Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers
    • Bae Y., Kataoka K. Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copolymers. Adv. Drug Deliv. Rev. 2009, 61:768-784.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 768-784
    • Bae, Y.1    Kataoka, K.2
  • 118
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • Torchilin V.P. Structure and design of polymeric surfactant-based drug delivery systems. J. Control. Release 2001, 73:137-172.
    • (2001) J. Control. Release , vol.73 , pp. 137-172
    • Torchilin, V.P.1
  • 119
    • 77956156055 scopus 로고    scopus 로고
    • Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers
    • Tyrrell Z.L., Shen Y., Radosz M. Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers. Prog. Polym. Sci. 2010, 35:1128-1143.
    • (2010) Prog. Polym. Sci. , vol.35 , pp. 1128-1143
    • Tyrrell, Z.L.1    Shen, Y.2    Radosz, M.3
  • 120
    • 4143074645 scopus 로고    scopus 로고
    • Micellar carriers based on block copolymers of poly(e{open}-caprolactone) and poly(ethylene glycol) for doxorubicin delivery
    • Shuai X., Ai H., Nasongkla N., Kim S., Gao J. Micellar carriers based on block copolymers of poly(e{open}-caprolactone) and poly(ethylene glycol) for doxorubicin delivery. J. Control. Release 2004, 98:415-426.
    • (2004) J. Control. Release , vol.98 , pp. 415-426
    • Shuai, X.1    Ai, H.2    Nasongkla, N.3    Kim, S.4    Gao, J.5
  • 121
    • 84893469695 scopus 로고    scopus 로고
    • Highly hemocompatible zwitterionic micelles stabilized by reversible cross-linkage for anti-cancer drug delivery
    • Lin W., He Y., Zhang J., Wang L., Wang Z., Ji F., Chen S. Highly hemocompatible zwitterionic micelles stabilized by reversible cross-linkage for anti-cancer drug delivery. Colloids Surf. B: Biointerfaces 2014, 115:384-390.
    • (2014) Colloids Surf. B: Biointerfaces , vol.115 , pp. 384-390
    • Lin, W.1    He, Y.2    Zhang, J.3    Wang, L.4    Wang, Z.5    Ji, F.6    Chen, S.7
  • 122
    • 78049341053 scopus 로고    scopus 로고
    • Multifunctionality of lipid-core micelles for drug delivery and tumour targeting
    • Sawant R.R., Torchilin V.P. Multifunctionality of lipid-core micelles for drug delivery and tumour targeting. Mol. Membr. Biol. 2010, 27:232-246.
    • (2010) Mol. Membr. Biol. , vol.27 , pp. 232-246
    • Sawant, R.R.1    Torchilin, V.P.2
  • 123
    • 0037148667 scopus 로고    scopus 로고
    • PEG-based micelles as carriers of contrast agents for different imaging modalities
    • Torchilin V.P. PEG-based micelles as carriers of contrast agents for different imaging modalities. Adv. Drug Deliv. Rev. 2002, 54:235-252.
    • (2002) Adv. Drug Deliv. Rev. , vol.54 , pp. 235-252
    • Torchilin, V.P.1
  • 125
    • 77956541489 scopus 로고    scopus 로고
    • Improved therapeutic effect of DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab')2 for hepatocellular carcinoma
    • Jin C., Qian N., Zhao W., Yang W., Bai L., Wu H., Wang M., Song W., Dou K. Improved therapeutic effect of DOX-PLGA-PEG micelles decorated with bivalent fragment HAb18 F(ab')2 for hepatocellular carcinoma. Biomacromolecules 2010, 11:2422-2431.
    • (2010) Biomacromolecules , vol.11 , pp. 2422-2431
    • Jin, C.1    Qian, N.2    Zhao, W.3    Yang, W.4    Bai, L.5    Wu, H.6    Wang, M.7    Song, W.8    Dou, K.9
  • 127
    • 24644438254 scopus 로고    scopus 로고
    • Lipid-core micelles for targeted drug delivery
    • Torchilin V.P. Lipid-core micelles for targeted drug delivery. Curr. Drug Deliv. 2005, 2:319-327.
    • (2005) Curr. Drug Deliv. , vol.2 , pp. 319-327
    • Torchilin, V.P.1
  • 128
    • 84890823140 scopus 로고    scopus 로고
    • ® F127-poly (methyl vinyl ether-alt-maleic acid) copolymer and production of its micelles for doxorubicin delivery in breast cancer
    • ® F127-poly (methyl vinyl ether-alt-maleic acid) copolymer and production of its micelles for doxorubicin delivery in breast cancer. Chem. Eng. 2014, 240:133-146.
    • (2014) Chem. Eng. , vol.240 , pp. 133-146
    • Varshosaz, J.1    Hassanzadeh, F.2    Sadeghi-aliabadi, H.3    Larian, Z.4    Rostami, M.5
  • 129
    • 84895041194 scopus 로고    scopus 로고
    • Redox-responsive polyanhydride micelles for cancer therapy
    • Wang J., Yang G., Guo X., Tang Z., Zhong Z., Zhou S. Redox-responsive polyanhydride micelles for cancer therapy. Biomaterials 2014, 35:3080-3090.
    • (2014) Biomaterials , vol.35 , pp. 3080-3090
    • Wang, J.1    Yang, G.2    Guo, X.3    Tang, Z.4    Zhong, Z.5    Zhou, S.6
  • 130
    • 84896707834 scopus 로고    scopus 로고
    • Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer
    • Abouzeid A.H., Patel N.R., Torchilin V.P. Polyethylene glycol-phosphatidylethanolamine (PEG-PE)/vitamin E micelles for co-delivery of paclitaxel and curcumin to overcome multi-drug resistance in ovarian cancer. Int. J. Pharm. 2014, 464:178-184.
    • (2014) Int. J. Pharm. , vol.464 , pp. 178-184
    • Abouzeid, A.H.1    Patel, N.R.2    Torchilin, V.P.3
  • 131
    • 84887626984 scopus 로고    scopus 로고
    • Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells
    • Ke X.-Y., Lin Ng V.W., Gao S.-J., Tong Y.W., Hedrick J.L., Yang Y.Y. Co-delivery of thioridazine and doxorubicin using polymeric micelles for targeting both cancer cells and cancer stem cells. Biomaterials 2014, 35:1096-1108.
    • (2014) Biomaterials , vol.35 , pp. 1096-1108
    • Ke, X.-Y.1    Lin Ng, V.W.2    Gao, S.-J.3    Tong, Y.W.4    Hedrick, J.L.5    Yang, Y.Y.6
  • 132
    • 84891831251 scopus 로고    scopus 로고
    • Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: a promising strategy to overcome drug resistance in cancer
    • Salzano G., Riehle R., Navarro G., Perche F., De Rosa G., Torchilin V.P. Polymeric micelles containing reversibly phospholipid-modified anti-survivin siRNA: a promising strategy to overcome drug resistance in cancer. Cancer Lett. 2014, 343:224-231.
    • (2014) Cancer Lett. , vol.343 , pp. 224-231
    • Salzano, G.1    Riehle, R.2    Navarro, G.3    Perche, F.4    De Rosa, G.5    Torchilin, V.P.6
  • 133
    • 47349097049 scopus 로고    scopus 로고
    • Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance
    • Lee E.S., Gao Z., Kim D., Park K., Kwon I.C., Bae Y.H. Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance. J. Control. Release 2008, 129:228-236.
    • (2008) J. Control. Release , vol.129 , pp. 228-236
    • Lee, E.S.1    Gao, Z.2    Kim, D.3    Park, K.4    Kwon, I.C.5    Bae, Y.H.6
  • 135
    • 33845378981 scopus 로고
    • Cascade molecules: a new approach to micelles. A [27]-arborol
    • Newkome G.R., Yao Z.Q., Baker G.R., Gupta V.K. Cascade molecules: a new approach to micelles. A [27]-arborol. J. Org. Chem. 1985, 50:2003-2004.
    • (1985) J. Org. Chem. , vol.50 , pp. 2003-2004
    • Newkome, G.R.1    Yao, Z.Q.2    Baker, G.R.3    Gupta, V.K.4
  • 136
    • 12844258906 scopus 로고    scopus 로고
    • Dendrimers and dendritic polymers in drug delivery
    • Gillies E.R., Fréchet J.M.J. Dendrimers and dendritic polymers in drug delivery. Drug Discov. Today 2005, 10:35-43.
    • (2005) Drug Discov. Today , vol.10 , pp. 35-43
    • Gillies, E.R.1    Fréchet, J.M.J.2
  • 137
    • 38349134916 scopus 로고    scopus 로고
    • Dendrimers as drug carriers: applications in different routes of drug administration
    • Cheng Y., Xu Z., Ma M., Xu T. Dendrimers as drug carriers: applications in different routes of drug administration. J. Pharm. Sci. 2008, 97:123-143.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 123-143
    • Cheng, Y.1    Xu, Z.2    Ma, M.3    Xu, T.4
  • 138
  • 139
    • 60749099362 scopus 로고    scopus 로고
    • Dendrimers as versatile platform in drug delivery applications
    • Svenson S. Dendrimers as versatile platform in drug delivery applications. Eur. J. Pharm. Biopharm. 2009, 71:445-462.
    • (2009) Eur. J. Pharm. Biopharm. , vol.71 , pp. 445-462
    • Svenson, S.1
  • 141
    • 28744445460 scopus 로고    scopus 로고
    • Dendrimer biocompatibility and toxicity
    • Duncan R., Izzo L. Dendrimer biocompatibility and toxicity. Adv. Drug Deliv. Rev. 2005, 57:2215-2237.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 2215-2237
    • Duncan, R.1    Izzo, L.2
  • 144
    • 79954579637 scopus 로고    scopus 로고
    • Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives
    • Cheng Y., Zhao L., Li Y., Xu T. Design of biocompatible dendrimers for cancer diagnosis and therapy: current status and future perspectives. Chem. Soc. Rev. 2011, 40:2673-2703.
    • (2011) Chem. Soc. Rev. , vol.40 , pp. 2673-2703
    • Cheng, Y.1    Zhao, L.2    Li, Y.3    Xu, T.4
  • 145
    • 18444392735 scopus 로고    scopus 로고
    • Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry
    • Tomalia D.A. Birth of a new macromolecular architecture: dendrimers as quantized building blocks for nanoscale synthetic polymer chemistry. Prog. Polym. Sci. 2005, 30:294-324.
    • (2005) Prog. Polym. Sci. , vol.30 , pp. 294-324
    • Tomalia, D.A.1
  • 146
    • 33645505167 scopus 로고    scopus 로고
    • Dendrimers: novel polymeric nanoarchitectures for solubility enhancement
    • Gupta U., Agashe H.B., Asthana A., Jain N.K. Dendrimers: novel polymeric nanoarchitectures for solubility enhancement. Biomacromolecules 2006, 7:649-658.
    • (2006) Biomacromolecules , vol.7 , pp. 649-658
    • Gupta, U.1    Agashe, H.B.2    Asthana, A.3    Jain, N.K.4
  • 147
    • 37549044726 scopus 로고    scopus 로고
    • Design, synthesis and potent pharmaceutical applications of glycodendrimers: a mini review
    • Li Y., Cheng Y., Xu T. Design, synthesis and potent pharmaceutical applications of glycodendrimers: a mini review. Curr. Drug Discov. Technol. 2007, 4:246-254.
    • (2007) Curr. Drug Discov. Technol. , vol.4 , pp. 246-254
    • Li, Y.1    Cheng, Y.2    Xu, T.3
  • 149
    • 0037433811 scopus 로고    scopus 로고
    • A PEGylated dendritic nanoparticulate carrier of fluorouracil
    • Bhadra D., Bhadra S., Jain S., Jain N.K. A PEGylated dendritic nanoparticulate carrier of fluorouracil. Int. J. Pharm. 2003, 257:111-124.
    • (2003) Int. J. Pharm. , vol.257 , pp. 111-124
    • Bhadra, D.1    Bhadra, S.2    Jain, S.3    Jain, N.K.4
  • 150
    • 0033657796 scopus 로고    scopus 로고
    • Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs
    • Kojima C., Kono K., Maruyama K., Takagishi T. Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs. Bioconjug. Chem. 2000, 11:910-917.
    • (2000) Bioconjug. Chem. , vol.11 , pp. 910-917
    • Kojima, C.1    Kono, K.2    Maruyama, K.3    Takagishi, T.4
  • 151
    • 4644264045 scopus 로고    scopus 로고
    • Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers
    • Gillies E.R., Jonsson T.B., Fréchet J.M.J. Stimuli-responsive supramolecular assemblies of linear-dendritic copolymers. J. Am. Chem. Soc. 2004, 126:11936-11943.
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 11936-11943
    • Gillies, E.R.1    Jonsson, T.B.2    Fréchet, J.M.J.3
  • 152
    • 0033376651 scopus 로고    scopus 로고
    • Dendrimer-platinate: a novel approach to cancer chemotherapy
    • Malik N., Evagorou E.G., Duncan R. Dendrimer-platinate: a novel approach to cancer chemotherapy. Anticancer Drugs 1999, 10:767-776.
    • (1999) Anticancer Drugs , vol.10 , pp. 767-776
    • Malik, N.1    Evagorou, E.G.2    Duncan, R.3
  • 154
    • 70450221930 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles based drug delivery systems
    • Kumari A., Yadav S.K., Yadav S.C. Biodegradable polymeric nanoparticles based drug delivery systems. Int. J. Pharm. 2010, 75:1-18.
    • (2010) Int. J. Pharm. , vol.75 , pp. 1-18
    • Kumari, A.1    Yadav, S.K.2    Yadav, S.C.3
  • 155
    • 0036707316 scopus 로고    scopus 로고
    • Biodegradable nanoparticles for drug delivery and targeting
    • Hans M.L., Lowman A.M. Biodegradable nanoparticles for drug delivery and targeting. Curr. Opin. Solid State Mater. Sci. 2002, 6:319-327.
    • (2002) Curr. Opin. Solid State Mater. Sci. , vol.6 , pp. 319-327
    • Hans, M.L.1    Lowman, A.M.2
  • 157
    • 0036324712 scopus 로고    scopus 로고
    • Rapid endo-lysosomal escape of poly(dl-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery
    • Panyam J., Zhou W.Z., Prabha S., Sahoo S.K., Labhasetwar V. Rapid endo-lysosomal escape of poly(dl-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery. FASEB J. 2002, 16:1217-1226.
    • (2002) FASEB J. , vol.16 , pp. 1217-1226
    • Panyam, J.1    Zhou, W.Z.2    Prabha, S.3    Sahoo, S.K.4    Labhasetwar, V.5
  • 158
    • 4644296183 scopus 로고    scopus 로고
    • Poly(lactic acid) nanoparticles labeled with biologically active Neutravidin™ for active targeting
    • Nobs L., Buchegger F., Gurny R., Allémann E. Poly(lactic acid) nanoparticles labeled with biologically active Neutravidin™ for active targeting. Eur. J. Pharm. Biopharm. 2004, 58:483-490.
    • (2004) Eur. J. Pharm. Biopharm. , vol.58 , pp. 483-490
    • Nobs, L.1    Buchegger, F.2    Gurny, R.3    Allémann, E.4
  • 159
    • 18044387257 scopus 로고    scopus 로고
    • Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-κB signal pathways
    • Ikezoe T., Yang Y., Bandobashi K., Saito T., Takemoto S., Machida H., Togitani K., Koeffler H.P., Taguchi H. Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-κB signal pathways. Mol. Cancer Ther. 2005, 4:578-586.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 578-586
    • Ikezoe, T.1    Yang, Y.2    Bandobashi, K.3    Saito, T.4    Takemoto, S.5    Machida, H.6    Togitani, K.7    Koeffler, H.P.8    Taguchi, H.9
  • 160
    • 33845895263 scopus 로고    scopus 로고
    • Studies on the oridonin-loaded poly(d,l-lactic acid) nanoparticles in vitro and in vivo
    • Xing J., Zhang D., Tan T. Studies on the oridonin-loaded poly(d,l-lactic acid) nanoparticles in vitro and in vivo. Int. J. Biol. Macromol. 2007, 40:153-158.
    • (2007) Int. J. Biol. Macromol. , vol.40 , pp. 153-158
    • Xing, J.1    Zhang, D.2    Tan, T.3
  • 161
    • 15044348714 scopus 로고    scopus 로고
    • Poly(ethylene oxide)-modified poly(e{open}-caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer
    • Shenoy D.B., Amiji M.M. Poly(ethylene oxide)-modified poly(e{open}-caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer. Int. J. Pharm. 2005, 293:261-270.
    • (2005) Int. J. Pharm. , vol.293 , pp. 261-270
    • Shenoy, D.B.1    Amiji, M.M.2
  • 162
    • 0034985630 scopus 로고    scopus 로고
    • Taxol-loaded block copolymer nanospheres composed of methoxy poly(ethylene glycol) and poly(e{open}-caprolactone) as novel anticancer drug carriers
    • Kim S.Y., Lee Y.M. Taxol-loaded block copolymer nanospheres composed of methoxy poly(ethylene glycol) and poly(e{open}-caprolactone) as novel anticancer drug carriers. Biomaterials 2001, 22:1697-1704.
    • (2001) Biomaterials , vol.22 , pp. 1697-1704
    • Kim, S.Y.1    Lee, Y.M.2
  • 163
    • 67651230648 scopus 로고    scopus 로고
    • Study on docetaxel-loaded nanoparticles with high antitumor efficacy against malignant melanoma
    • Zheng D., Li X., Xu H., Lu X., Hu Y., Fan W. Study on docetaxel-loaded nanoparticles with high antitumor efficacy against malignant melanoma. Acta Biochim. Biophys. Sin. 2009, 41:578-587.
    • (2009) Acta Biochim. Biophys. Sin. , vol.41 , pp. 578-587
    • Zheng, D.1    Li, X.2    Xu, H.3    Lu, X.4    Hu, Y.5    Fan, W.6
  • 164
    • 68249152032 scopus 로고    scopus 로고
    • Preparation, characterization, in-vitro drug release and cellular uptake of poly(caprolactone) grafted dextran copolymeric nanoparticles loaded with anticancer drug
    • Prabu P., Chaudhari A.A., Dharmaraj N., Khil M.S., Park S.Y., Kim H.Y. Preparation, characterization, in-vitro drug release and cellular uptake of poly(caprolactone) grafted dextran copolymeric nanoparticles loaded with anticancer drug. J. Biomed. Mater. Res. A 2009, 90A:1128-1136.
    • (2009) J. Biomed. Mater. Res. A , vol.90 A , pp. 1128-1136
    • Prabu, P.1    Chaudhari, A.A.2    Dharmaraj, N.3    Khil, M.S.4    Park, S.Y.5    Kim, H.Y.6
  • 166
    • 33645034817 scopus 로고    scopus 로고
    • Nanoencapsulation: I. Methods for preparation of drug-loaded polymeric nanoparticles
    • Pinto Reis C., Neufeld R.J., Ribeiro A.J., Veiga F. Nanoencapsulation: I. Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine 2006, 2:8-21.
    • (2006) Nanomedicine , vol.2 , pp. 8-21
    • Pinto Reis, C.1    Neufeld, R.J.2    Ribeiro, A.J.3    Veiga, F.4
  • 167
    • 0027432534 scopus 로고
    • Drug-loaded nanoparticles - preparation methods and drug targeting issues
    • Allemann E., Gurny R., Doelker E. Drug-loaded nanoparticles - preparation methods and drug targeting issues. Eur. J. Pharm. Biopharm. 1993, 39:173-191.
    • (1993) Eur. J. Pharm. Biopharm. , vol.39 , pp. 173-191
    • Allemann, E.1    Gurny, R.2    Doelker, E.3
  • 168
    • 0037020525 scopus 로고    scopus 로고
    • Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity
    • Fonseca C., Simões S., Gaspar R. Paclitaxel-loaded PLGA nanoparticles: preparation, physicochemical characterization and in vitro anti-tumoral activity. J. Control. Release 2002, 83:273-286.
    • (2002) J. Control. Release , vol.83 , pp. 273-286
    • Fonseca, C.1    Simões, S.2    Gaspar, R.3
  • 169
    • 78349303879 scopus 로고    scopus 로고
    • Preparation and characterization of chitosan-polylactide composites blended with Cloisite 30B for control release of the anticancer drug paclitaxel
    • Nanda R., Sasmal A., Nayak P.L. Preparation and characterization of chitosan-polylactide composites blended with Cloisite 30B for control release of the anticancer drug paclitaxel. Carbohydr. Polym. 2011, 83:988-994.
    • (2011) Carbohydr. Polym. , vol.83 , pp. 988-994
    • Nanda, R.1    Sasmal, A.2    Nayak, P.L.3
  • 170
    • 78349308871 scopus 로고    scopus 로고
    • Development and in vivo evaluation of an oral drug delivery system for paclitaxel
    • Iqbal J., Sarti F., Perera G., Bernkop-Schnürch A. Development and in vivo evaluation of an oral drug delivery system for paclitaxel. Biomaterials 2011, 32:170-175.
    • (2011) Biomaterials , vol.32 , pp. 170-175
    • Iqbal, J.1    Sarti, F.2    Perera, G.3    Bernkop-Schnürch, A.4
  • 171
    • 12344281758 scopus 로고    scopus 로고
    • Commercial challenges of protein drug delivery
    • Brown L.R. Commercial challenges of protein drug delivery. Expert Opin. Drug Deliv. 2005, 2:29-42.
    • (2005) Expert Opin. Drug Deliv. , vol.2 , pp. 29-42
    • Brown, L.R.1
  • 172
    • 84922998117 scopus 로고    scopus 로고
    • Micro e Nanopartículas Biomacromoleculares
    • Universidade Fernando Pessoa, Porto, E.B. Souto, C.M. Lopes (Eds.)
    • Reis C.P. Micro e Nanopartículas Biomacromoleculares. Novas Formas Farmacêuticas para Administração de Fármacos, edições 2011, 199-236. Universidade Fernando Pessoa, Porto. E.B. Souto, C.M. Lopes (Eds.).
    • (2011) Novas Formas Farmacêuticas para Administração de Fármacos, edições , pp. 199-236
    • Reis, C.P.1
  • 173
    • 22644437189 scopus 로고    scopus 로고
    • Albumin-insulin conjugate releasing insulin slowly under physiological conditions: a new concept for long-acting insulin
    • Shechter Y., Mironchik M., Rubinraut S., Saul A., Tsubery H., Fridkin M. Albumin-insulin conjugate releasing insulin slowly under physiological conditions: a new concept for long-acting insulin. Bioconjug. Chem. 2005, 16:913-920.
    • (2005) Bioconjug. Chem. , vol.16 , pp. 913-920
    • Shechter, Y.1    Mironchik, M.2    Rubinraut, S.3    Saul, A.4    Tsubery, H.5    Fridkin, M.6
  • 175
    • 0038815811 scopus 로고    scopus 로고
    • Targeted delivery of expression plasmids to the lung via macroaggregated polyethylenimine-albumin conjugates
    • Humana Press, B. Driscoll (Ed.)
    • Orson F., Kinsey B., Bhogal B., Song L., Densmore C., Barry M. Targeted delivery of expression plasmids to the lung via macroaggregated polyethylenimine-albumin conjugates. Lung Cancer 2003, 575-590. Humana Press. B. Driscoll (Ed.).
    • (2003) Lung Cancer , pp. 575-590
    • Orson, F.1    Kinsey, B.2    Bhogal, B.3    Song, L.4    Densmore, C.5    Barry, M.6
  • 176
    • 0038555755 scopus 로고    scopus 로고
    • Biopolymer albumin for diagnosis and in drug delivery
    • Patil G.V. Biopolymer albumin for diagnosis and in drug delivery. Drug Dev. Res. 2003, 58:219-247.
    • (2003) Drug Dev. Res. , vol.58 , pp. 219-247
    • Patil, G.V.1
  • 177
    • 0036001387 scopus 로고    scopus 로고
    • Pharmaceutical strategies utilizing recombinant human serum albumin
    • Tuan Giam Chuang V., Kragh-Hansen U., Otagiri M. Pharmaceutical strategies utilizing recombinant human serum albumin. Pharm. Res. 2002, 19:569-577.
    • (2002) Pharm. Res. , vol.19 , pp. 569-577
    • Tuan Giam Chuang, V.1    Kragh-Hansen, U.2    Otagiri, M.3
  • 178
    • 84855850311 scopus 로고    scopus 로고
    • Impact of albumin on drug delivery - new applications on the horizon
    • Elsadek B., Kratz F. Impact of albumin on drug delivery - new applications on the horizon. J. Control. Release 2012, 157:4-28.
    • (2012) J. Control. Release , vol.157 , pp. 4-28
    • Elsadek, B.1    Kratz, F.2
  • 179
    • 84855861744 scopus 로고    scopus 로고
    • Albumin: a versatile carrier for drug delivery
    • Park K. Albumin: a versatile carrier for drug delivery. J. Control. Release 2012, 157:3.
    • (2012) J. Control. Release , vol.157 , pp. 3
    • Park, K.1
  • 180
    • 84855813140 scopus 로고    scopus 로고
    • Albumin-based nanoparticles as potential controlled release drug delivery systems
    • Elzoghby A.O., Samy W.M., Elgindy N.A. Albumin-based nanoparticles as potential controlled release drug delivery systems. J. Control. Release 2012, 157:168-182.
    • (2012) J. Control. Release , vol.157 , pp. 168-182
    • Elzoghby, A.O.1    Samy, W.M.2    Elgindy, N.A.3
  • 181
    • 33645881087 scopus 로고    scopus 로고
    • Albumin-derived nanocarriers: substrates for enhanced cell adhesive ligand display and cell motility
    • Sharma R.I., Pereira M., Schwarzbauer J.E., Moghe P.V. Albumin-derived nanocarriers: substrates for enhanced cell adhesive ligand display and cell motility. Biomaterials 2006, 27:3589-3598.
    • (2006) Biomaterials , vol.27 , pp. 3589-3598
    • Sharma, R.I.1    Pereira, M.2    Schwarzbauer, J.E.3    Moghe, P.V.4
  • 182
    • 0032214525 scopus 로고    scopus 로고
    • Surface-modified biodegradable albumin nano- and microspheres. II: Effect of surface charges on in vitro phagocytosis and biodistribution in rats
    • Roser M., Fischer D., Kissel T. Surface-modified biodegradable albumin nano- and microspheres. II: Effect of surface charges on in vitro phagocytosis and biodistribution in rats. Eur. J. Pharm. Biopharm. 1998, 46:255-263.
    • (1998) Eur. J. Pharm. Biopharm. , vol.46 , pp. 255-263
    • Roser, M.1    Fischer, D.2    Kissel, T.3
  • 183
    • 56949084877 scopus 로고    scopus 로고
    • Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles
    • Kratz F. Albumin as a drug carrier: design of prodrugs, drug conjugates and nanoparticles. J. Control. Release 2008, 132:171-183.
    • (2008) J. Control. Release , vol.132 , pp. 171-183
    • Kratz, F.1
  • 184
    • 34447623755 scopus 로고    scopus 로고
    • Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles
    • Dreis S., Rothweiler F., Michaelis M., Cinatl J., Kreuter J., Langer K. Preparation, characterisation and maintenance of drug efficacy of doxorubicin-loaded human serum albumin (HSA) nanoparticles. Int. J. Pharm. 2007, 341:207-214.
    • (2007) Int. J. Pharm. , vol.341 , pp. 207-214
    • Dreis, S.1    Rothweiler, F.2    Michaelis, M.3    Cinatl, J.4    Kreuter, J.5    Langer, K.6
  • 185
    • 32944482677 scopus 로고    scopus 로고
    • Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer
    • Gradishar W.J., Tjulandin S., Davidson N., Shaw H., Desai N., Bhar P., Hawkins M., O'Shaughnessy J. Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer. J. Clin. Oncol. 2005, 23:7794-7803.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 7794-7803
    • Gradishar, W.J.1    Tjulandin, S.2    Davidson, N.3    Shaw, H.4    Desai, N.5    Bhar, P.6    Hawkins, M.7    O'Shaughnessy, J.8
  • 186
    • 68949114599 scopus 로고    scopus 로고
    • Significantly longer progression-free survival with nab-paclitaxel compared with docetaxel as first-line therapy for metastatic breast cancer
    • Gradishar W.J., Krasnojon D., Cheporov S., Makhson A.N., Manikhas G.M., Clawson A., Bhar P. Significantly longer progression-free survival with nab-paclitaxel compared with docetaxel as first-line therapy for metastatic breast cancer. J. Clin. Oncol. 2009, 27:3611-3619.
    • (2009) J. Clin. Oncol. , vol.27 , pp. 3611-3619
    • Gradishar, W.J.1    Krasnojon, D.2    Cheporov, S.3    Makhson, A.N.4    Manikhas, G.M.5    Clawson, A.6    Bhar, P.7
  • 187
    • 0026608797 scopus 로고
    • Gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis
    • Schnitzer J.E. gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis. Am. J. Physiol. Heart Circ. Physiol. 1992, 262:H246-H254.
    • (1992) Am. J. Physiol. Heart Circ. Physiol. , vol.262 , pp. H246-H254
    • Schnitzer, J.E.1
  • 188
    • 0030798998 scopus 로고    scopus 로고
    • Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway
    • Tiruppathi C., Song W., Bergenfeldt M., Sass P., Malik A.B. Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway. J. Biol. Chem. 1997, 272:25968-25975.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25968-25975
    • Tiruppathi, C.1    Song, W.2    Bergenfeldt, M.3    Sass, P.4    Malik, A.B.5
  • 189
    • 73849141603 scopus 로고    scopus 로고
    • Size and dynamics of caveolae studied using nanoparticles in living endothelial cells
    • Wang Z., Tiruppathi C., Minshall R.D., Malik A.B. Size and dynamics of caveolae studied using nanoparticles in living endothelial cells. ACS Nano 2009, 3:4110-4116.
    • (2009) ACS Nano , vol.3 , pp. 4110-4116
    • Wang, Z.1    Tiruppathi, C.2    Minshall, R.D.3    Malik, A.B.4
  • 190
    • 9344233312 scopus 로고    scopus 로고
    • Paclitaxel-loaded gelatin nanoparticles for intravesical bladder cancer therapy
    • Lu Z., Yeh T.-K., Tsai M., Au J.L.-S., Wientjes M.G. Paclitaxel-loaded gelatin nanoparticles for intravesical bladder cancer therapy. Clin. Cancer Res. 2004, 10:7677-7684.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 7677-7684
    • Lu, Z.1    Yeh, T.-K.2    Tsai, M.3    Au, J.L.-S.4    Wientjes, M.G.5
  • 191
  • 192
    • 33744991713 scopus 로고    scopus 로고
    • Casein micelle structure: models and muddles
    • Horne D.S. Casein micelle structure: models and muddles. Curr. Opin. Colloid Interface Sci. 2006, 11:148-153.
    • (2006) Curr. Opin. Colloid Interface Sci. , vol.11 , pp. 148-153
    • Horne, D.S.1
  • 193
    • 77955276587 scopus 로고    scopus 로고
    • β-Casein-based nanovehicles for oral delivery of chemotherapeutic drugs: drug-protein interactions and mitoxantrone loading capacity
    • Shapira A., Markman G., Assaraf Y.G., Livney Y.D. β-Casein-based nanovehicles for oral delivery of chemotherapeutic drugs: drug-protein interactions and mitoxantrone loading capacity. Nanomedicine 2010, 6:547-555.
    • (2010) Nanomedicine , vol.6 , pp. 547-555
    • Shapira, A.1    Markman, G.2    Assaraf, Y.G.3    Livney, Y.D.4
  • 194
    • 77957346768 scopus 로고    scopus 로고
    • Beta-casein nanoparticles as an oral delivery system for chemotherapeutic drugs: impact of drug structure and properties on co-assembly
    • Shapira A., Assaraf Y.G., Epstein D., Livney Y.D. Beta-casein nanoparticles as an oral delivery system for chemotherapeutic drugs: impact of drug structure and properties on co-assembly. Pharm. Res. 2010, 27:2175-2186.
    • (2010) Pharm. Res. , vol.27 , pp. 2175-2186
    • Shapira, A.1    Assaraf, Y.G.2    Epstein, D.3    Livney, Y.D.4
  • 195
    • 84856607406 scopus 로고    scopus 로고
    • β-Casein nanoparticle-based oral drug delivery system for potential treatment of gastric carcinoma: stability, target-activated release and cytotoxicity
    • Shapira A., Davidson I., Avni N., Assaraf Y.G., Livney Y.D. β-Casein nanoparticle-based oral drug delivery system for potential treatment of gastric carcinoma: stability, target-activated release and cytotoxicity. Eur. J. Pharm. Biopharm. 2012, 80:298-305.
    • (2012) Eur. J. Pharm. Biopharm. , vol.80 , pp. 298-305
    • Shapira, A.1    Davidson, I.2    Avni, N.3    Assaraf, Y.G.4    Livney, Y.D.5
  • 196
    • 70349978292 scopus 로고    scopus 로고
    • Combination therapy: opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines
    • Greco F., Vicent M.J. Combination therapy: opportunities and challenges for polymer-drug conjugates as anticancer nanomedicines. Adv. Drug Deliv. Rev. 2009, 61:1203-1213.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 1203-1213
    • Greco, F.1    Vicent, M.J.2
  • 197
    • 84907196712 scopus 로고    scopus 로고
    • Well-defined polymer-drug conjugate engineered with redox and pH-sensitive release mechanism for efficient delivery of paclitaxel
    • Lv S., Tang Z., Zhang D., Song W., Li M., Lin J., Liu H., Chen X. Well-defined polymer-drug conjugate engineered with redox and pH-sensitive release mechanism for efficient delivery of paclitaxel. J. Control. Release 2014, 194:220-227.
    • (2014) J. Control. Release , vol.194 , pp. 220-227
    • Lv, S.1    Tang, Z.2    Zhang, D.3    Song, W.4    Li, M.5    Lin, J.6    Liu, H.7    Chen, X.8
  • 198
    • 84897373234 scopus 로고    scopus 로고
    • Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: impact of the carrier structure onto synergistic action in the treatment of solid tumours
    • Etrych T., Šubr V., Laga R., Říhová B., Ulbrich K. Polymer conjugates of doxorubicin bound through an amide and hydrazone bond: impact of the carrier structure onto synergistic action in the treatment of solid tumours. Eur. J. Pharm. Sci. 2014, 58:1-12.
    • (2014) Eur. J. Pharm. Sci. , vol.58 , pp. 1-12
    • Etrych, T.1    Šubr, V.2    Laga, R.3    Říhová, B.4    Ulbrich, K.5
  • 199
    • 84901617707 scopus 로고    scopus 로고
    • Combination cytotoxicity of backbone degradable HPMA copolymer gemcitabine and platinum conjugates toward human ovarian carcinoma cells
    • Duangjai A., Luo K., Zhou Y., Yang J., Kopeček J. Combination cytotoxicity of backbone degradable HPMA copolymer gemcitabine and platinum conjugates toward human ovarian carcinoma cells. Eur. J. Pharm. Biopharm. 2014, 87:187-196.
    • (2014) Eur. J. Pharm. Biopharm. , vol.87 , pp. 187-196
    • Duangjai, A.1    Luo, K.2    Zhou, Y.3    Yang, J.4    Kopeček, J.5
  • 201
    • 33748323064 scopus 로고    scopus 로고
    • Poly(γ,l-glutamic acid)-cisplatin conjugate effectively inhibits human breast tumor xenografted in nude mice
    • Ye H., Jin L., Hu R., Yi Z., Li J., Wu Y., Xi X., Wu Z. Poly(γ,l-glutamic acid)-cisplatin conjugate effectively inhibits human breast tumor xenografted in nude mice. Biomaterials. 2006, 27:5958-5965.
    • (2006) Biomaterials. , vol.27 , pp. 5958-5965
    • Ye, H.1    Jin, L.2    Hu, R.3    Yi, Z.4    Li, J.5    Wu, Y.6    Xi, X.7    Wu, Z.8
  • 202
    • 84908368867 scopus 로고    scopus 로고
    • Carboxymethylcellulose-tetrahydrocurcumin conjugates for colon-specific delivery of a novel anti-cancer agent, 4-amino tetrahydrocurcumin
    • Plyduang T., Lomlim L., Yuenyongsawad S., Wiwattanapatapee R. Carboxymethylcellulose-tetrahydrocurcumin conjugates for colon-specific delivery of a novel anti-cancer agent, 4-amino tetrahydrocurcumin. Eur. J. Pharm. Biopharm. 2014, 88:351-360.
    • (2014) Eur. J. Pharm. Biopharm. , vol.88 , pp. 351-360
    • Plyduang, T.1    Lomlim, L.2    Yuenyongsawad, S.3    Wiwattanapatapee, R.4
  • 204
    • 0002196524 scopus 로고
    • Polymer conjugated macromolecular drugs for tumor-specific targeting
    • John Wiley and Sons Ltd, USA, A.J. Domb (Ed.)
    • Maeda H. Polymer conjugated macromolecular drugs for tumor-specific targeting. Polymeric Site-specific Pharmacotherapy 1994, 95-116. John Wiley and Sons Ltd, USA. A.J. Domb (Ed.).
    • (1994) Polymeric Site-specific Pharmacotherapy , pp. 95-116
    • Maeda, H.1
  • 207
    • 0345367901 scopus 로고    scopus 로고
    • HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line
    • Minko T., Kopečková P., Pozharov V., Kopeček J. HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line. J. Control. Release 1998, 54:223-233.
    • (1998) J. Control. Release , vol.54 , pp. 223-233
    • Minko, T.1    Kopečková, P.2    Pozharov, V.3    Kopeček, J.4
  • 209
    • 33751357186 scopus 로고    scopus 로고
    • Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice
    • Sirova M., Strohalm J., Subr V., Plocova D., Rossmann P., Mrkvan T., Ulbrich K., Rihova B. Treatment with HPMA copolymer-based doxorubicin conjugate containing human immunoglobulin induces long-lasting systemic anti-tumour immunity in mice. Cancer Immunol. Immunother. 2007, 56:35-47.
    • (2007) Cancer Immunol. Immunother. , vol.56 , pp. 35-47
    • Sirova, M.1    Strohalm, J.2    Subr, V.3    Plocova, D.4    Rossmann, P.5    Mrkvan, T.6    Ulbrich, K.7    Rihova, B.8
  • 211
    • 0028954776 scopus 로고
    • Site-directed delivery of anthracyclines for treatment of cancer
    • Trail P.A., Willner D., Hellstrom K.E. Site-directed delivery of anthracyclines for treatment of cancer. Drug Dev. Res. 1995, 34:196-209.
    • (1995) Drug Dev. Res. , vol.34 , pp. 196-209
    • Trail, P.A.1    Willner, D.2    Hellstrom, K.E.3
  • 212
    • 1842369073 scopus 로고    scopus 로고
    • Antitumor activity of carcinoma-reactive BR96-doxorubicin conjugate against human carcinomas in athymic mice and rats and syngeneic rat carcinomas in immunecompetent rats
    • Sjögren H.O., Isaksson M., Willner D., Hellström I., Hellström K.E., Trail P.A. Antitumor activity of carcinoma-reactive BR96-doxorubicin conjugate against human carcinomas in athymic mice and rats and syngeneic rat carcinomas in immunecompetent rats. Cancer Res. 1997, 57:4530-4536.
    • (1997) Cancer Res. , vol.57 , pp. 4530-4536
    • Sjögren, H.O.1    Isaksson, M.2    Willner, D.3    Hellström, I.4    Hellström, K.E.5    Trail, P.A.6
  • 214
    • 0007887541 scopus 로고    scopus 로고
    • Immunoconjugate therapy of solid tumors: studies with BR96-doxorubicin
    • Marcel Dekker, New York, M. Grossbard (Ed.)
    • Saleh M.N., LoBuglio A.F., Trail P.A. Immunoconjugate therapy of solid tumors: studies with BR96-doxorubicin. Monoclonal Antibody-Based Therapy of Cancer 1998, 397-416. Marcel Dekker, New York. M. Grossbard (Ed.).
    • (1998) Monoclonal Antibody-Based Therapy of Cancer , pp. 397-416
    • Saleh, M.N.1    LoBuglio, A.F.2    Trail, P.A.3
  • 215
    • 78649315943 scopus 로고    scopus 로고
    • To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery
    • Danhier F., Feron O., Préat V. To exploit the tumor microenvironment: passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. J. Control. Release 2010, 148:135-146.
    • (2010) J. Control. Release , vol.148 , pp. 135-146
    • Danhier, F.1    Feron, O.2    Préat, V.3
  • 216
    • 57049158125 scopus 로고    scopus 로고
    • Drug targeting and tumor heterogeneity
    • Bae Y.H. Drug targeting and tumor heterogeneity. J. Control. Release 2009, 133:2-3.
    • (2009) J. Control. Release , vol.133 , pp. 2-3
    • Bae, Y.H.1
  • 217
    • 33750019824 scopus 로고    scopus 로고
    • The transferrin receptor. Part II: Targeted delivery of therapeutic agents into cancer cells
    • Daniels T.R., Delgado T., Helguera G., Penichet M.L. The transferrin receptor. Part II: Targeted delivery of therapeutic agents into cancer cells. Clin. Immunol. 2006, 121:159-176.
    • (2006) Clin. Immunol. , vol.121 , pp. 159-176
    • Daniels, T.R.1    Delgado, T.2    Helguera, G.3    Penichet, M.L.4
  • 218
    • 67649849650 scopus 로고    scopus 로고
    • Folate-targeted therapeutic and imaging agents for cancer
    • Low P.S., Kularatne S.A. Folate-targeted therapeutic and imaging agents for cancer. Curr. Opin. Chem. Biol. 2009, 13:256-262.
    • (2009) Curr. Opin. Chem. Biol. , vol.13 , pp. 256-262
    • Low, P.S.1    Kularatne, S.A.2
  • 219
    • 1142273203 scopus 로고    scopus 로고
    • Drug targeting to the colon with lectins and neoglycoconjugates
    • Minko T. Drug targeting to the colon with lectins and neoglycoconjugates. Adv. Drug Deliv. Rev. 2004, 56:491-509.
    • (2004) Adv. Drug Deliv. Rev. , vol.56 , pp. 491-509
    • Minko, T.1
  • 220
    • 84858684164 scopus 로고    scopus 로고
    • The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy
    • Doane T.L., Burda C. The unique role of nanoparticles in nanomedicine: imaging, drug delivery and therapy. Chem. Soc. Rev. 2012, 41:2885-2911.
    • (2012) Chem. Soc. Rev. , vol.41 , pp. 2885-2911
    • Doane, T.L.1    Burda, C.2
  • 222
    • 84871964643 scopus 로고    scopus 로고
    • Nano-graphene in biomedicine: theranostic applications
    • Yang K., Feng L., Shi X., Liu Z. Nano-graphene in biomedicine: theranostic applications. Chem. Soc. Rev. 2013, 42:530-547.
    • (2013) Chem. Soc. Rev. , vol.42 , pp. 530-547
    • Yang, K.1    Feng, L.2    Shi, X.3    Liu, Z.4
  • 223
    • 84919683158 scopus 로고    scopus 로고
    • TPGS-stabilized NaYbF4:Er upconversion nanoparticles for dual-modal fluorescent/CT imaging and anticancer drug delivery to overcome multi-drug resistance
    • Tian G., Zheng X., Zhang X., Yin W., Yu J., Wang D., Zhang Z., Yang X., Gu Z., Zhao Y. TPGS-stabilized NaYbF4:Er upconversion nanoparticles for dual-modal fluorescent/CT imaging and anticancer drug delivery to overcome multi-drug resistance. Biomaterials 2015, 40:107-116.
    • (2015) Biomaterials , vol.40 , pp. 107-116
    • Tian, G.1    Zheng, X.2    Zhang, X.3    Yin, W.4    Yu, J.5    Wang, D.6    Zhang, Z.7    Yang, X.8    Gu, Z.9    Zhao, Y.10
  • 225
    • 80053184892 scopus 로고    scopus 로고
    • Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers
    • Kievit F.M., Zhang M. Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers. Adv. Mater. (Deerfield Beach Fla.) 2011, 23:H217-H247.
    • (2011) Adv. Mater. (Deerfield Beach Fla.) , vol.23 , pp. H217-H247
    • Kievit, F.M.1    Zhang, M.2
  • 227
    • 42949170904 scopus 로고    scopus 로고
    • Theranostic nanomedicine for cancer
    • Sumer B., Gao J. Theranostic nanomedicine for cancer. Nanomedicine 2008, 3:137-140.
    • (2008) Nanomedicine , vol.3 , pp. 137-140
    • Sumer, B.1    Gao, J.2
  • 228
    • 78649968090 scopus 로고    scopus 로고
    • Nanotheranostics and image-guided drug delivery: current concepts and future directions
    • Lammers T., Kiessling F., Hennink W.E., Storm G. Nanotheranostics and image-guided drug delivery: current concepts and future directions. Mol. Pharm. 2010, 7:1899-1912.
    • (2010) Mol. Pharm. , vol.7 , pp. 1899-1912
    • Lammers, T.1    Kiessling, F.2    Hennink, W.E.3    Storm, G.4
  • 229
    • 79960841631 scopus 로고    scopus 로고
    • Single-phased luminescent mesoporous nanoparticles for simultaneous cell imaging and anticancer drug delivery
    • Di W., Ren X., Zhao H., Shirahata N., Sakka Y., Qin W. Single-phased luminescent mesoporous nanoparticles for simultaneous cell imaging and anticancer drug delivery. Biomaterials 2011, 32:7226-7233.
    • (2011) Biomaterials , vol.32 , pp. 7226-7233
    • Di, W.1    Ren, X.2    Zhao, H.3    Shirahata, N.4    Sakka, Y.5    Qin, W.6
  • 231
    • 48149095263 scopus 로고    scopus 로고
    • Chemical design of nanoparticle probes for high-performance magnetic resonance imaging
    • Jun Y.-W., Lee J.-H., Cheon J. Chemical design of nanoparticle probes for high-performance magnetic resonance imaging. Angew. Chem. Int. Ed. 2008, 47:5122-5135.
    • (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 5122-5135
    • Jun, Y.-W.1    Lee, J.-H.2    Cheon, J.3
  • 233
    • 84861669644 scopus 로고    scopus 로고
    • ®-The first FDA-approved nano-drug: lessons learned
    • ®-The first FDA-approved nano-drug: lessons learned. J. Control. Release 2012, 160:117-134.
    • (2012) J. Control. Release , vol.160 , pp. 117-134
    • Barenholz, Y.1
  • 234
    • 84893737274 scopus 로고    scopus 로고
    • What nanomedicine in the clinic right now really forms nanoparticles?
    • Svenson S. What nanomedicine in the clinic right now really forms nanoparticles?. Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 2014, 6:125-135.
    • (2014) Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. , vol.6 , pp. 125-135
    • Svenson, S.1
  • 235
    • 0035286282 scopus 로고    scopus 로고
    • Liposomal encapsulated anthracyclines: new therapeutic horizons
    • Muggia F.M. Liposomal encapsulated anthracyclines: new therapeutic horizons. Curr. Oncol. Rep. 2001, 3:156-162.
    • (2001) Curr. Oncol. Rep. , vol.3 , pp. 156-162
    • Muggia, F.M.1
  • 238
    • 84923052155 scopus 로고    scopus 로고
    • Celsion Corporation. Available from: (accessed 18.11.14).
    • THERMODOX®. Celsion Corporation. Available from: (accessed 18.11.14). http://celsion.com/docs/technology_thermodox.
  • 239
    • 84923025307 scopus 로고    scopus 로고
    • DaunoXome® (liposomal daunorubicin). Galen - Advanced Human Health, United Kingdom, Available from: (accessed 21.11.14).
    • DaunoXome® (liposomal daunorubicin). Galen - Advanced Human Health, United Kingdom, 2013. Available from: (accessed 21.11.14). http://www.galen.co.uk/products/daunoxome.
    • (2013)
  • 240
    • 84862776276 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14)
    • Drugs at FDA FDA - U.S. Food and Drug Administration USA 2014, Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/202497s000lbl.pdf (accessed 21.11.14).
    • (2014) FDA - U.S. Food and Drug Administration USA
  • 241
    • 84923052154 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14).
    • DepoCyte®. EMA - European Medicines Agency, 2012. Available from: (accessed 21.11.14). http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/human/medicines/000317/human_med_000740.jsp%26mid=WC0b01ac058001d124.
    • (2012)
  • 242
    • 84923052153 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14)
    • CPX-351 and Acute Myeloid Leukemia Celator Pharmaceuticals 2014, Available from: http://www.celatorpharma.com/new/products_cpx351.html (accessed 21.11.14).
    • (2014) Celator Pharmaceuticals
  • 243
    • 77955936898 scopus 로고    scopus 로고
    • The status of platinum anticancer drugs in the clinic and in clinical trials
    • Wheate N.J., Walker S., Craig G.E., Oun R. The status of platinum anticancer drugs in the clinic and in clinical trials. Dalton Trans. 2010, 39:8113-8127.
    • (2010) Dalton Trans. , vol.39 , pp. 8113-8127
    • Wheate, N.J.1    Walker, S.2    Craig, G.E.3    Oun, R.4
  • 244
    • 84923025306 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14)
    • Product/Pipeline - Active Targeting Drug Delivery System Mebiopharm Co., Ltd. 2011, Available from: http://www.mebiopharm.com/english/pro.html (accessed 21.11.14).
    • (2011) Mebiopharm Co., Ltd.
  • 246
    • 84922971397 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14)
    • Azaya therapeutics - products pipeline Azaya Therapeutics 2014, Available from: http://www.mebiopharm.com/english/pro.html (accessed 21.11.14).
    • (2014) Azaya Therapeutics
  • 247
    • 84873252557 scopus 로고    scopus 로고
    • Liposomal drug delivery systems: from concept to clinical applications
    • Allen T.M., Cullis P.R. Liposomal drug delivery systems: from concept to clinical applications. Adv. Drug Deliv. Rev. 2013, 65:36-48.
    • (2013) Adv. Drug Deliv. Rev. , vol.65 , pp. 36-48
    • Allen, T.M.1    Cullis, P.R.2
  • 248
    • 84923052153 scopus 로고    scopus 로고
    • Available from: (accessed 22.11.14)
    • CPX-1 and Colorectal Cancer Celator Pharmaceuticals 2014, Available from: http://www.celatorpharma.com/new/products_CPX1.html (accessed 22.11.14).
    • (2014) Celator Pharmaceuticals
  • 249
    • 84923052152 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14).
    • Pipeline - Lipotecan®. Taiwan Liposome Company, 2013. Available from: (accessed 21.11.14). http://www.tlcbio.com/en-global/pipeline/202.
    • (2013)
  • 250
    • 84922058575 scopus 로고    scopus 로고
    • Available from: (accessed 22.11.14)
    • Safety Study of Infusion of SGT-53 to Treat Solid Tumors Clinical Trials Search 2014, Available from: http://www.clinicaltrialssearch.org/safety-study-of-infusion-of-sgt-53-to-treat-solid-tumors-nct00470613.html (accessed 22.11.14).
    • (2014) Clinical Trials Search
  • 251
    • 84922975857 scopus 로고    scopus 로고
    • Available from: (accessed 22.11.14)
    • Pipeline Products Tekmira Pharmaceuticals Corporation 2014, Available from: http://www.supratek.com/pipeline (accessed 22.11.14).
    • (2014) Tekmira Pharmaceuticals Corporation
  • 253
    • 84907599028 scopus 로고    scopus 로고
    • A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer
    • Ahn H., Jung M., Sym S., Shin D., Kang S., Kyung S., Park J.-W., Jeong S., Cho E. A phase II trial of Cremorphor EL-free paclitaxel (Genexol-PM) and gemcitabine in patients with advanced non-small cell lung cancer. Cancer Chemother. Pharmacol. 2014, 74:277-282.
    • (2014) Cancer Chemother. Pharmacol. , vol.74 , pp. 277-282
    • Ahn, H.1    Jung, M.2    Sym, S.3    Shin, D.4    Kang, S.5    Kyung, S.6    Park, J.-W.7    Jeong, S.8    Cho, E.9
  • 254
    • 84922998116 scopus 로고    scopus 로고
    • Available from: (accessed 21.11.14).
    • NanoCarrier® - Research and Development - Pipeline. NanoCarrier® - Leading Edge Nanotechnology, 2013. Available from: (accessed 21.11.14). http://www.nanocarrier.co.jp/en/research/pipeline/index.html.
    • (2013)
  • 255
    • 84906786049 scopus 로고    scopus 로고
    • Progress of drug-loaded polymeric micelles into clinical studies
    • Cabral H., Kataoka K. Progress of drug-loaded polymeric micelles into clinical studies. J. Control. Release 2014, 190:465-476.
    • (2014) J. Control. Release , vol.190 , pp. 465-476
    • Cabral, H.1    Kataoka, K.2
  • 256
    • 84922998115 scopus 로고    scopus 로고
    • Available from: (accessed 22.11.14)
    • Pipeline Supreatek Pharma Inc. 2014, Available from: http://www.supratek.com/pipeline (accessed 22.11.14).
    • (2014) Supreatek Pharma Inc.
  • 257
    • 84922998114 scopus 로고    scopus 로고
    • Dendrimer Drug Delivery (DEP™). Starpharma, Available from: (accessed 21.11.14).
    • Dendrimer Drug Delivery (DEP™). Starpharma, 2014. Available from: (accessed 21.11.14). http://www.starpharma.com/drug_delivery.
    • (2014)
  • 258
    • 84923025305 scopus 로고    scopus 로고
    • Arrowhead Research Corporation. Available from: (accessed 23.11.14).
    • CALAA-01 Pipeline. Arrowhead Research Corporation. Available from: (accessed 23.11.14). http://www.arrowheadresearch.com/programs/calaa-01.
  • 259
    • 79958100231 scopus 로고    scopus 로고
    • Safety and efficacy of nab-paclitaxel in the treatment of patients with breast cancer
    • Vishnu P., Roy V. Safety and efficacy of nab-paclitaxel in the treatment of patients with breast cancer. Breast Cancer (Auckl.) 2011, 5:53-65.
    • (2011) Breast Cancer (Auckl.) , vol.5 , pp. 53-65
    • Vishnu, P.1    Roy, V.2
  • 260
    • 73149090374 scopus 로고    scopus 로고
    • Nanoparticle albumin bound (nab) technology: targeting tumors through the endothelial gp60 receptor and SPARC
    • Desai N. Nanoparticle albumin bound (nab) technology: targeting tumors through the endothelial gp60 receptor and SPARC. Nanomedicine 2007, 3:339.
    • (2007) Nanomedicine , vol.3 , pp. 339
    • Desai, N.1
  • 261
    • 84922971396 scopus 로고    scopus 로고
    • Available from: (accessed 22.11.14)
    • Orphan Oncology Products Onxeo 2014, Available from: http://www.onxeo.com/en/nos-produits/portefeuilles-produits/orphelins-oncologie/ (accessed 22.11.14).
    • (2014) Onxeo
  • 262
    • 84922971395 scopus 로고    scopus 로고
    • Paclitaxel or Polyglutamate Paclitaxel or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Peritoneal Cancer or Fallopian Tube Cancer. cti Biopharma, 2014. Available from: (accessed 22.11.14).
    • Paclitaxel or Polyglutamate Paclitaxel or Observation in Treating Patients With Stage III or Stage IV Ovarian Epithelial or Peritoneal Cancer or Fallopian Tube Cancer. cti Biopharma, 2014. Available from: (accessed 22.11.14). http://www.ctibiopharma.com/clinical-trials/trials-compound/.
  • 263
    • 84866788430 scopus 로고    scopus 로고
    • Available from: (accessed 22.11.14)
    • FDA Approves pegaspargase (Oncaspar, Enzon Pharmaceuticals, Inc.) for the first-line treatment of patients with acute lymphoblastic leukemia FDA - U.S. Food and Drug Administration 2006, Available from: http://www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProductsandTobacco/CDER/ucm095609.htm (accessed 22.11.14).
    • (2006) FDA - U.S. Food and Drug Administration
  • 266
    • 70349984537 scopus 로고    scopus 로고
    • XMT-1001, a novel polymeric camptothecin pro-drug in clinical development for patients with advanced cancer
    • Yurkovetskiy A.V., Fram R.J. XMT-1001, a novel polymeric camptothecin pro-drug in clinical development for patients with advanced cancer. Adv. Drug Deliv. Rev. 2009, 61:1193-1202.
    • (2009) Adv. Drug Deliv. Rev. , vol.61 , pp. 1193-1202
    • Yurkovetskiy, A.V.1    Fram, R.J.2
  • 269
    • 84922971394 scopus 로고    scopus 로고
    • NKTR-105 Demonstrates Superior Antitumor Activity and Improved Pharmacokinetics Over Docetaxel in Preclinical Studies Presented at AACR
    • Available from: (accessed 22.11.14)
    • NKTR-105 Demonstrates Superior Antitumor Activity and Improved Pharmacokinetics Over Docetaxel in Preclinical Studies Presented at AACR. Nektar Therap. 2009, Available from: http://ir.nektar.com/releasedetail.cfm?releaseid=378943 (accessed 22.11.14).
    • (2009) Nektar Therap.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.