The development and testing of a new temperature-sensitive drug delivery system for the treatment of solid tumors

Advanced Drug Delivery Reviews

Volumn 53, Issue 3, 2001, Pages 285-305

  Needham, David ^a   Dewhirst, Mark W ^b  

^a Duke University   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Doxorubicin; FaDu tumors; Hyperthermia; Liposomes; Lysolipid

Indexed keywords

DISEASE CONTROL; LIPIDS; TESTING; TUMORS;

DRUG DELIVERY SYSTEM;

DRUG THERAPY;

1,2 DIPALIMITOYL SN GLYCERO 3 PHOSPHOCHOLINE; ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; DRUG CARRIER; LIPOSOME; MACROGOL 2000; MELPHALAN; METHOTREXATE; PHOSPHOLIPASE A2; UNCLASSIFIED DRUG;

BODY TEMPERATURE; CANCER CHEMOTHERAPY; CONTROLLED DRUG RELEASE; DRUG ACCUMULATION; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG SCREENING; DRUG TISSUE LEVEL; DRUG UPTAKE; HEAT TREATMENT; HUMAN; HYPERTHERMIA; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; REVIEW; SKIN FLAP; SOLID TUMOR; TARGET CELL; TEMPERATURE SENSITIVITY; TUMOR GROWTH; TUMOR MODEL; TUMOR XENOGRAFT;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; LIPID BILAYERS; LIPOSOMES; TEMPERATURE;

EID: 0035981024     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(01)00233-2     Document Type: Review

References (72)

1. Enhancement of the phase transition permeability of DPPC liposomes by incorporation of MPPC: A new temperature-sensitive liposome for use with mild hyperthermia
2. A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model
3. Hyperthermia increases extravasation of technicium-99m labeled liposomes in feline sarcomas
4. Efficacy of liposomes and hyperthermia in a human tumor xenograft model: Importance of triggered drug release
5. Barriers to drug delivery in solid tumors
6. Assessment of the impact of local control on clinical outcome
7. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer
8. Pathogenesis of testicular germ cell tumours
9. Guidelines for the diagnosis and therapy of testicular cancer and new developments
10. Modification of tumor blood flow: Current status and future directions
11. Diffusion of univalent ions across the lamellae of swollen phospholipids
12. The carrier potential of liposomes in bioogy and medicine
13. The stealth liposome: A prototypical biomaterial
14. Commentary. Rantosomes and ravosomes
15. Liposome-based patents for use in the pharmaceutical industry
16. Quality control of lipoosmes
17. Clinical evaluation of liposomal anthracyclins
18. Liposomal anthracyclins. From basics to clinical approval of pegylated liposomal doxorubicin
19. Poly(ethylene glycol)-lipid conjugates promote bilayer formation in mixtures of non-bilayer-forming lipids
20. Controlled destabilization of a liposomal drug delivery system enhances mitoxantrone antitumor activity
21. pH-sensitive liposomes: Acid-induced liposome fusion
22. Polyelectrolyte-sensitized phospholipid vesicles
23. Effect of bilayer cholesterol and surface grafted poly(ethylene glycol) on pH-induced release of contents from liposomes by poly(2-ethylacrylic acid)
24. Drug delivery by phospholipase A2 degradable liposomes
25. Enzymatic degradation of polymer covered SOPC-liposomes in relation to drug delivery
26. Structure of liposomal membranes in relation to permeation
27. Phospholipase activity in 9,10-dimethyl-1,2-benzanthracene-induced mammary tumors of rats
28. Mechanochemistry of lipid vesicles examined by micropipet manipulation
29. Use of micropipet manipulation techniques to measure the properties of giant vesicles
30. Electro-mechanical permeabilization of lipid vesicles: Role of membrane tension and compressibility
31. In vivo electroporation and stable transformation of skin cells on newborn mice by plasmid DNA
32. The influence of electromagnetic fields on biological and model membranes
33. A synthetic mimetic of the secretory granule
34. Lipid-coated microhydrogels for triggered release of doxorubicin
35. Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effects of temperature and cholesterol
36. Permeability of lipid bilayers near the phase transition
37. Model of interfacial melting
38. On defects in different phases of two-dimensional lipid bilayers
39. Materials properties of lipid-coated microbubles
40. The function of sterols in membranes
41. Effect of lanthanum ions on the phase transitions of lecithin bilayers
42. Design of liposomes for enhanced local release of drugs by hyperthermia
43. Temperature dependence of adriamycin, cis-diamminedichloroplatinum, bleomycin, and 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity in vitro
44. Hyperthermia, adriamycin transport, and cytotoxicity in drug-sensitive and -resistant Chinese hamster ovary cells
45. Use of temperature-sensitive liposomes in the selective delivery of methotrexate and cis-platinum analogues to murine bladder tumor
46. Enhanced delivery of doxorubicin to tumor by long-circulating thermosensitive liposomes and local hyperthermia
47. Thermosensitive sterically stabilized liposomes: Formulation and in vitro studies on mechanism of doxorubicin release by bovine serum and human plasma
48. In vitro evaluation of the association of thermosensitive liposome-encapsulated doxorubicin with hyperthermia
49. Treatment of solid L1210 murine tumors with local hyperthermia and temperature-sensitive liposomes containing methotrexate
50. Thermosensitive liposomes: Extravasation and release of contents in tumor microvascular networks
51. Hyperthermia and liposomes: A review
52. Intraperitoneal cisplatin and regional hyperthermia for ovarian carcinoma
53. Combined external beam irradiation and external regional hyperthermia for locally advanced adenocarcinoma of the prostate
54. Lipid bilayer expansion and mechanical disruption in solutions of water soluble bile acid
55. Lysolipid exchange with lipid vesicle membranes
56. Exchange of monooleoylphosphatidycholine as monomer and micelle with membranes containing grafted polyethyleneglycol
57. Hyperthermic treatment of malignant diseases: Current status and a view toward the future
58. Cumulative minutes with T90 greater than Tempindex is predictive of response of superficial malignancies to hyperthermia and radiation
59. Increased microvascular permeability contributes to preferential accumulation of stealth liposomes in tumor tissue
60. Measurement of protein and liposome extravasation in microvascular networks using fluorescence video microscopy
61. Polymer-grafted liposomes: Physical basis for the 'stealth' property
62. Extravasation of stealth liposomes into tumors. Direct measurement of accumulation and vascular permeability using a skin flap window chamber
63. Microvascular permeability of albumin, vascular surface area and vascular volume measured in human adenocarcinoma LS174T using dorsal chamber in SCID mice
64. Simultaneous measurement of liposome extravasation and content release in tumors
65. Local hyperthermia improves uptake of a chimeric monoclonal antibody in a subcutaneous xenograft model