메뉴 건너뛰기




Volumn 56, Issue 4, 2004, Pages 491-509

Drug targeting to the colon with lectins and neoglycoconjugates

Author keywords

Colon cancer; Liposomes; Polymers; Prodrug; Review; Targeted drug delivery

Indexed keywords

BIOLOGICAL ORGANS; CELLS; TISSUE; TUMORS;

EID: 1142273203     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.addr.2003.10.017     Document Type: Article
Times cited : (220)

References (101)
  • 2
    • 0141886989 scopus 로고    scopus 로고
    • Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides
    • Dharap S.S., Qiu B., Williams G., Sinko P., Stein S., Minko T., Molecular targeting of drug delivery systems to ovarian cancer by BH3 and LHRH peptides. J. Control. Rel. 91:2003;61-73.
    • (2003) J. Control. Rel. , vol.91 , pp. 61-73
    • Dharap, S.S.1    Qiu, B.2    Williams, G.3    Sinko, P.4    Stein, S.5    Minko, T.6
  • 3
    • 0037443713 scopus 로고    scopus 로고
    • Peptide and protein drug delivery to and into tumors: Challenges and solutions
    • Torchilin V.P., Lukyanov A.N. Peptide and protein drug delivery to and into tumors: challenges and solutions. Drug Discov. Today. 8:2003;259-266.
    • (2003) Drug Discov. Today , vol.8 , pp. 259-266
    • Torchilin, V.P.1    Lukyanov, A.N.2
  • 6
    • 0029897299 scopus 로고    scopus 로고
    • Investigation of nifedipine absorption in different regions of the human gastrointestinal (GI) tract after simultaneous administration of 13C- and 12C-nifedipine
    • Bode H., Brendel E., Ahr G., Fuhr U., Harder S., Staib A.H. Investigation of nifedipine absorption in different regions of the human gastrointestinal (GI) tract after simultaneous administration of 13C- and 12C-nifedipine. Eur. J. Clin. Pharmacol. 50:1996;195-201.
    • (1996) Eur. J. Clin. Pharmacol. , vol.50 , pp. 195-201
    • Bode, H.1    Brendel, E.2    Ahr, G.3    Fuhr, U.4    Harder, S.5    Staib, A.H.6
  • 8
    • 0032916177 scopus 로고    scopus 로고
    • Evaluation of colonic absorbability of drugs in dogs using a novel colon targeted delivery capsule (CTDC)
    • Ishibashi T., Ikegami K., Kubo H., Kobayashi M., Mizobe M., Yoshino H. Evaluation of colonic absorbability of drugs in dogs using a novel colon targeted delivery capsule (CTDC). J. Control. Release. 59:1999;361-376.
    • (1999) J. Control. Release , vol.59 , pp. 361-376
    • Ishibashi, T.1    Ikegami, K.2    Kubo, H.3    Kobayashi, M.4    Mizobe, M.5    Yoshino, H.6
  • 9
    • 0028606845 scopus 로고
    • Absorption of isosorbide-5-mononitrate at specific sites in the gastrointestinal tract
    • Kramer W.G. Absorption of isosorbide-5-mononitrate at specific sites in the gastrointestinal tract. J. Clin. Pharmacol. 34:1994;1218-1221.
    • (1994) J. Clin. Pharmacol. , vol.34 , pp. 1218-1221
    • Kramer, W.G.1
  • 10
    • 0033998408 scopus 로고    scopus 로고
    • Studies of pectin HM/Eudragit RL/Eudragit NE film-coating formulations intended for colonic drug delivery
    • Semde R., Amighi K., Devleeschouwer M.J., Moes A.J. Studies of pectin HM/Eudragit RL/Eudragit NE film-coating formulations intended for colonic drug delivery. Int. J. Pharm. 197:2000;181-192.
    • (2000) Int. J. Pharm. , vol.197 , pp. 181-192
    • Semde, R.1    Amighi, K.2    Devleeschouwer, M.J.3    Moes, A.J.4
  • 11
    • 0035783246 scopus 로고    scopus 로고
    • Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues
    • Herrera-Ruiz D., Wang Q., Gudmundsson O.S., Cook T.J., Smith R.L., Faria T.N., Knipp G.T. Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues. AAPS Pharm. Sci. 3:2001;E9.
    • (2001) AAPS Pharm. Sci. , vol.3 , pp. 9
    • Herrera-Ruiz, D.1    Wang, Q.2    Gudmundsson, O.S.3    Cook, T.J.4    Smith, R.L.5    Faria, T.N.6    Knipp, G.T.7
  • 12
    • 0034983708 scopus 로고    scopus 로고
    • Developmental expression of PEPT1 and PEPT2 in rat small intestine, colon, and kidney
    • Shen H., Smith D.E., Brosius F.C. III. Developmental expression of PEPT1 and PEPT2 in rat small intestine, colon, and kidney. Pediatr. Res. 49:2001;789-795.
    • (2001) Pediatr. Res. , vol.49 , pp. 789-795
    • Shen, H.1    Smith, D.E.2    Brosius III, F.C.3
  • 14
    • 0034657529 scopus 로고    scopus 로고
    • Intestinal absorption of peptides through the enterocytes
    • Ziv E., Bendayan M. Intestinal absorption of peptides through the enterocytes. Microsc. Res. Tech. 49:2000;346-352.
    • (2000) Microsc. Res. Tech. , vol.49 , pp. 346-352
    • Ziv, E.1    Bendayan, M.2
  • 15
    • 0026092788 scopus 로고
    • Gamma scintigraphy and neutron activation techniques in the in vivo assessment of orally administered dosage forms
    • Digenis G.A., Sandefer E. Gamma scintigraphy and neutron activation techniques in the in vivo assessment of orally administered dosage forms. Crit. Rev. Ther. Drug Carrier Syst. 7:1991;309-345.
    • (1991) Crit. Rev. Ther. Drug Carrier Syst. , vol.7 , pp. 309-345
    • Digenis, G.A.1    Sandefer, E.2
  • 16
    • 0037006593 scopus 로고    scopus 로고
    • Diethyl ether fraction of Labrasol having a stronger absorption enhancing effect on gentamicin than Labrasol itself
    • Hu Z., Prasad Yv.R., Tawa R., Konishi T., Ishida M., Shibata N., Takada K. Diethyl ether fraction of Labrasol having a stronger absorption enhancing effect on gentamicin than Labrasol itself. Int. J. Pharm. 234:2002;223-235.
    • (2002) Int. J. Pharm. , vol.234 , pp. 223-235
    • Hu, Z.1    Prasad, Yv.R.2    Tawa, R.3    Konishi, T.4    Ishida, M.5    Shibata, N.6    Takada, K.7
  • 17
    • 0033776338 scopus 로고    scopus 로고
    • Enhanced enteral bioavailability of vancomycin using water-in-oil-in- water multiple emulsion incorporating highly purified unsaturated fatty acid
    • Kajita M., Morishita M., Takayama K., Chiba Y., Tokiwa S., Nagai T. Enhanced enteral bioavailability of vancomycin using water-in-oil-in-water multiple emulsion incorporating highly purified unsaturated fatty acid. J. Pharm. Sci. 89:2000;1243-1252.
    • (2000) J. Pharm. Sci. , vol.89 , pp. 1243-1252
    • Kajita, M.1    Morishita, M.2    Takayama, K.3    Chiba, Y.4    Tokiwa, S.5    Nagai, T.6
  • 18
    • 0030448341 scopus 로고    scopus 로고
    • Targeting of drugs and delivery systems to specific sites in the gastrointestinal tract
    • Fell J.T. Targeting of drugs and delivery systems to specific sites in the gastrointestinal tract. J. Anat. 189:1996;517-519.
    • (1996) J. Anat. , vol.189 , pp. 517-519
    • Fell, J.T.1
  • 19
    • 0028033502 scopus 로고
    • Targeting drugs to the colon: Delivery systems for oral administration
    • Ashford M., Fell J.T. Targeting drugs to the colon: delivery systems for oral administration. J. Drug Targeting. 2:1994;241-257.
    • (1994) J. Drug Targeting , vol.2 , pp. 241-257
    • Ashford, M.1    Fell, J.T.2
  • 23
    • 0037425743 scopus 로고    scopus 로고
    • Gut flora in health and disease
    • Guarner F., Malagelada J.R. Gut flora in health and disease. Lancet. 361:2003;512-519.
    • (2003) Lancet , vol.361 , pp. 512-519
    • Guarner, F.1    Malagelada, J.R.2
  • 24
    • 0035859973 scopus 로고    scopus 로고
    • Polysaccharides in colon-specific drug delivery
    • Sinha V.R., Kumria R. Polysaccharides in colon-specific drug delivery. Int. J. Pharm. 224:2001;19-38.
    • (2001) Int. J. Pharm. , vol.224 , pp. 19-38
    • Sinha, V.R.1    Kumria, R.2
  • 25
    • 0036637572 scopus 로고    scopus 로고
    • An in vitro and in vivo investigation into the suitability of bacterially triggered delivery system for colon targeting
    • Raghavan C.V., Muthulingam C., Jenita J.A., Ravi T.K. An in vitro and in vivo investigation into the suitability of bacterially triggered delivery system for colon targeting. Chem. Pharm. Bull. (Tokyo). 50:2002;892-895.
    • (2002) Chem. Pharm. Bull. (Tokyo) , vol.50 , pp. 892-895
    • Raghavan, C.V.1    Muthulingam, C.2    Jenita, J.A.3    Ravi, T.K.4
  • 26
    • 0037203695 scopus 로고    scopus 로고
    • Oral delayed-release system based on Zn-pectinate gel (ZPG) microparticles as an alternative carrier to calcium pectinate beads for colonic drug delivery
    • El-Gibaly I. Oral delayed-release system based on Zn-pectinate gel (ZPG) microparticles as an alternative carrier to calcium pectinate beads for colonic drug delivery. Int. J. Pharm. 232:2002;199-211.
    • (2002) Int. J. Pharm. , vol.232 , pp. 199-211
    • El-Gibaly, I.1
  • 27
    • 0026501131 scopus 로고
    • Colonic drug delivery: Enhanced release of indomethacin from cross-linked chondroitin matrix in rat cecal content
    • Rubinstein A., Nakar D., Sintov A. Colonic drug delivery: enhanced release of indomethacin from cross-linked chondroitin matrix in rat cecal content. Pharm. Res. 9:1992;276-278.
    • (1992) Pharm. Res. , vol.9 , pp. 276-278
    • Rubinstein, A.1    Nakar, D.2    Sintov, A.3
  • 28
    • 0035807463 scopus 로고    scopus 로고
    • Improved oral bioavailability of artemisinin through inclusion complexation with beta- and gamma-cyclodextrins
    • Wong J.W., Yuen K.H. Improved oral bioavailability of artemisinin through inclusion complexation with beta- and gamma-cyclodextrins. Int. J. Pharm. 227:2001;177-185.
    • (2001) Int. J. Pharm. , vol.227 , pp. 177-185
    • Wong, J.W.1    Yuen, K.H.2
  • 29
    • 0037133114 scopus 로고    scopus 로고
    • Colon-specific delivery of prednisolone-appended alpha-cyclodextrin conjugate: Alleviation of systemic side effect after oral administration
    • Yano H., Hirayama F., Kamada M., Arima H., Uekama K. Colon-specific delivery of prednisolone-appended alpha-cyclodextrin conjugate: alleviation of systemic side effect after oral administration. J. Control. Release. 79:2002;103-112.
    • (2002) J. Control. Release , vol.79 , pp. 103-112
    • Yano, H.1    Hirayama, F.2    Kamada, M.3    Arima, H.4    Uekama, K.5
  • 30
    • 0036792656 scopus 로고    scopus 로고
    • Synthesis of an enzyme-dependent prodrug and evaluation of its potential for colon targeting
    • Pang Y.N., Zhang Y., Zhang Z.R. Synthesis of an enzyme-dependent prodrug and evaluation of its potential for colon targeting. World J. Gastroenterol. 8:2002;913-917.
    • (2002) World J. Gastroenterol. , vol.8 , pp. 913-917
    • Pang, Y.N.1    Zhang, Y.2    Zhang, Z.R.3
  • 31
    • 0036579776 scopus 로고    scopus 로고
    • Paclitaxel delivery systems: The use of amino acid linkers in the conjugation of paclitaxel with carboxymethyldextran to create prodrugs
    • Sugahara S., Kajiki M., Kuriyama H., Kobayashi T.R. Paclitaxel delivery systems: the use of amino acid linkers in the conjugation of paclitaxel with carboxymethyldextran to create prodrugs. Biol. Pharm. Bull. 25:2002;632-641.
    • (2002) Biol. Pharm. Bull. , vol.25 , pp. 632-641
    • Sugahara, S.1    Kajiki, M.2    Kuriyama, H.3    Kobayashi, T.R.4
  • 33
    • 0035997045 scopus 로고    scopus 로고
    • In vitro drug release studies on guar gum-based colon targeted oral drug delivery systems of 5-fluorouracil
    • Krishnaiah Y.S., Satyanarayana V., Dinesh Kumar B., Karthikeyan R.S. In vitro drug release studies on guar gum-based colon targeted oral drug delivery systems of 5-fluorouracil. Eur. J. Pharm. Sci. 16:2002;185-192.
    • (2002) Eur. J. Pharm. Sci. , vol.16 , pp. 185-192
    • Krishnaiah, Y.S.1    Satyanarayana, V.2    Dinesh Kumar, B.3    Karthikeyan, R.S.4
  • 34
    • 0037331308 scopus 로고    scopus 로고
    • Characterization of methacrylated inulin hydrogels designed for colon targeting: In vitro release of BSA
    • Van den Mooter G., Vervoort L., Kinget R. Characterization of methacrylated inulin hydrogels designed for colon targeting: in vitro release of BSA. Pharm. Res. 20:2003;303-307.
    • (2003) Pharm. Res. , vol.20 , pp. 303-307
    • Van Den Mooter, G.1    Vervoort, L.2    Kinget, R.3
  • 35
    • 0037436032 scopus 로고    scopus 로고
    • Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid
    • Wiwattanapatapee R., Lomlim L., Saramunee K. Dendrimers conjugates for colonic delivery of 5-aminosalicylic acid. J. Control. Release. 88:2003;1-9.
    • (2003) J. Control. Release , vol.88 , pp. 1-9
    • Wiwattanapatapee, R.1    Lomlim, L.2    Saramunee, K.3
  • 36
    • 0345148785 scopus 로고    scopus 로고
    • Enteric polymers as binders and coating materials in multiple-unit site-specific drug delivery systems
    • Marvola M., Nykanen P., Rautio S., Isonen N., Autere A. Enteric polymers as binders and coating materials in multiple-unit site-specific drug delivery systems. Eur. J. Pharm. Sci. 7:1999;259-267.
    • (1999) Eur. J. Pharm. Sci. , vol.7 , pp. 259-267
    • Marvola, M.1    Nykanen, P.2    Rautio, S.3    Isonen, N.4    Autere, A.5
  • 37
    • 0035965499 scopus 로고    scopus 로고
    • Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon
    • Nykanen P., Lempaa S., Aaltonen M.L., Jurjenson H., Veski P., Marvola M. Citric acid as excipient in multiple-unit enteric-coated tablets for targeting drugs on the colon. Int. J. Pharm. 229:2001;155-162.
    • (2001) Int. J. Pharm. , vol.229 , pp. 155-162
    • Nykanen, P.1    Lempaa, S.2    Aaltonen, M.L.3    Jurjenson, H.4    Veski, P.5    Marvola, M.6
  • 38
    • 0037027874 scopus 로고    scopus 로고
    • Binders for colon-specific drug delivery: An in vitro evaluation
    • Sinha V.R., Kumria R. Binders for colon-specific drug delivery: an in vitro evaluation. Int. J. Pharm. 249:2002;23-31.
    • (2002) Int. J. Pharm. , vol.249 , pp. 23-31
    • Sinha, V.R.1    Kumria, R.2
  • 39
    • 0034005158 scopus 로고    scopus 로고
    • A pH-dependent colon targeted oral drug delivery system using methacrylic acid copolymers: II. Manipulation of drug release using Eudragit L100 and Eudragit S100 combinations
    • Khan M.Z., Stedul H.P., Kurjakovic N. A pH-dependent colon targeted oral drug delivery system using methacrylic acid copolymers: II. Manipulation of drug release using Eudragit L100 and Eudragit S100 combinations. Drug Dev. Ind. Pharm. 26:2000;549-554.
    • (2000) Drug Dev. Ind. Pharm. , vol.26 , pp. 549-554
    • Khan, M.Z.1    Stedul, H.P.2    Kurjakovic, N.3
  • 41
    • 0041181628 scopus 로고    scopus 로고
    • HPMA copolymer-anticancer drug conjugates: Design, activity, and mechanism of action
    • Kopecek J., Kopeckova P., Minko T., Lu Z. HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action. Eur. J. Pharm. Biopharm. 50:2000;61-81.
    • (2000) Eur. J. Pharm. Biopharm. , vol.50 , pp. 61-81
    • Kopecek, J.1    Kopeckova, P.2    Minko, T.3    Lu, Z.4
  • 43
    • 0037384279 scopus 로고    scopus 로고
    • Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy
    • Zeisig R., Ress A., Fichtner I., Walther W. Lipoplexes with alkylphospholipid as new helper lipid for efficient in vitro and in vivo gene transfer in tumor therapy. Cancer Gene Ther. 10:2003;302-311.
    • (2003) Cancer Gene Ther. , vol.10 , pp. 302-311
    • Zeisig, R.1    Ress, A.2    Fichtner, I.3    Walther, W.4
  • 45
    • 0037081743 scopus 로고    scopus 로고
    • 5-Fluoroindole-3-acetic acid: A prodrug activated by a peroxidase with potential for use in targeted cancer therapy
    • Folkes L.K., Greco O., Dachs G.U., Stratford M.R., Wardman P. 5-Fluoroindole-3-acetic acid: a prodrug activated by a peroxidase with potential for use in targeted cancer therapy. Biochem. Pharmacol. 63:2002;265-272.
    • (2002) Biochem. Pharmacol. , vol.63 , pp. 265-272
    • Folkes, L.K.1    Greco, O.2    Dachs, G.U.3    Stratford, M.R.4    Wardman, P.5
  • 46
    • 0031959770 scopus 로고    scopus 로고
    • Galectins: Versatile modulators of cell adhesion, cell proliferation, and cell death
    • Perillo N.L., Marcus M.E., Baum L.G. Galectins: versatile modulators of cell adhesion, cell proliferation, and cell death. J. Mol. Med. 76:1998;402-412.
    • (1998) J. Mol. Med. , vol.76 , pp. 402-412
    • Perillo, N.L.1    Marcus, M.E.2    Baum, L.G.3
  • 47
    • 0035733810 scopus 로고    scopus 로고
    • Potential of polysaccharide anchored liposomes in drug delivery, targeting and immunization
    • Sihorkar V., Vyas S.P. Potential of polysaccharide anchored liposomes in drug delivery, targeting and immunization. J. Pharm. Pharmaceut. Sci. 4:2001;138-158.
    • (2001) J. Pharm. Pharmaceut. Sci. , vol.4 , pp. 138-158
    • Sihorkar, V.1    Vyas, S.P.2
  • 48
    • 0027414461 scopus 로고
    • Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma
    • Lotz M.M., Andrews C.W., Korzelius C.A., Lee E.C., Steele G.D., Clarke A., Mercurio A.M. Decreased expression of Mac-2 (carbohydrate binding protein 35) and loss of its nuclear localization are associated with the neoplastic progression of colon carcinoma. Proc. Natl. Acad. Sci. USA. 90:1993;3466-3470.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3466-3470
    • Lotz, M.M.1    Andrews, C.W.2    Korzelius, C.A.3    Lee, E.C.4    Steele, G.D.5    Clarke, A.6    Mercurio, A.M.7
  • 49
    • 0029027525 scopus 로고
    • Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells
    • Ohannesian D.W., Lotan D., Thomas P., Jessup J.M., Fukuda M., Gabius H.J., Lotan R. Carcinoembryonic antigen and other glycoconjugates act as ligands for galectin-3 in human colon carcinoma cells. Cancer Res. 55:1995;2191-2199.
    • (1995) Cancer Res. , vol.55 , pp. 2191-2199
    • Ohannesian, D.W.1    Lotan, D.2    Thomas, P.3    Jessup, J.M.4    Fukuda, M.5    Gabius, H.J.6    Lotan, R.7
  • 50
    • 0029073986 scopus 로고
    • Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon
    • Schoeppner H.L., Raz A., Ho S.B., Bresalier R.S. Expression of an endogenous galactose-binding lectin correlates with neoplastic progression in the colon. Cancer. 75:1995;2818-2826.
    • (1995) Cancer , vol.75 , pp. 2818-2826
    • Schoeppner, H.L.1    Raz, A.2    Ho, S.B.3    Bresalier, R.S.4
  • 52
    • 0035725755 scopus 로고    scopus 로고
    • Glycohistochemistry: The why and how of detection and localization of endogenous lectins
    • Gabius H.J. Glycohistochemistry: the why and how of detection and localization of endogenous lectins. Anat. Histol. Embryol. 30:2001;3-31.
    • (2001) Anat. Histol. Embryol. , vol.30 , pp. 3-31
    • Gabius, H.J.1
  • 53
    • 0029034658 scopus 로고
    • Receptor mediated glycotargeting
    • Wadhwa M.S., Rice K.G. Receptor mediated glycotargeting. J. Drug Targeting. 3:1995;111-127.
    • (1995) J. Drug Targeting , vol.3 , pp. 111-127
    • Wadhwa, M.S.1    Rice, K.G.2
  • 54
    • 0036727315 scopus 로고    scopus 로고
    • Expression of human intestinal mucin is modulated by the beta-galactoside binding protein galectin-3 in colon cancer
    • Dudas S.P., Yunker C.K., Sternberg L.R., Byrd J.C., Bresalier R.S. Expression of human intestinal mucin is modulated by the beta-galactoside binding protein galectin-3 in colon cancer. Gastroenterology. 123:2002;817-826.
    • (2002) Gastroenterology , vol.123 , pp. 817-826
    • Dudas, S.P.1    Yunker, C.K.2    Sternberg, L.R.3    Byrd, J.C.4    Bresalier, R.S.5
  • 56
  • 59
    • 0032424017 scopus 로고    scopus 로고
    • Lectin-mediated drug targeting: Quantification of binding and internalization of wheat germ agglutinin and Solanum tuberosum lectin using Caco-2 and HT-29 cells
    • Wirth M., Hamilton G., Gabor F. Lectin-mediated drug targeting: quantification of binding and internalization of wheat germ agglutinin and Solanum tuberosum lectin using Caco-2 and HT-29 cells. J. Drug Targeting. 6:1998;95-104.
    • (1998) J. Drug Targeting , vol.6 , pp. 95-104
    • Wirth, M.1    Hamilton, G.2    Gabor, F.3
  • 60
    • 0031848767 scopus 로고    scopus 로고
    • Lectin-mediated drug targeting: Preparation, binding characteristics, and antiproliferative activity of wheat germ agglutinin conjugated doxorubicin on Caco-2 cells
    • Wirth M., Fuchs A., Wolf M., Ertl B., Gabor F. Lectin-mediated drug targeting: preparation, binding characteristics, and antiproliferative activity of wheat germ agglutinin conjugated doxorubicin on Caco-2 cells. Pharm. Res. 15:1998;1031-1037.
    • (1998) Pharm. Res. , vol.15 , pp. 1031-1037
    • Wirth, M.1    Fuchs, A.2    Wolf, M.3    Ertl, B.4    Gabor, F.5
  • 61
    • 0036709119 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: Discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model
    • Wirth M., Kneuer C., Lehr C.M., Gabor F. Lectin-mediated drug delivery: discrimination between cytoadhesion and cytoinvasion and evidence for lysosomal accumulation of wheat germ agglutinin in the Caco-2 model. J. Drug Targeting. 10:2002;439-448.
    • (2002) J. Drug Targeting , vol.10 , pp. 439-448
    • Wirth, M.1    Kneuer, C.2    Lehr, C.M.3    Gabor, F.4
  • 62
    • 0037133115 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: Influence of mucin on cytoadhesion of plant lectins in vitro
    • Wirth M., Gerhardt K., Wurm C., Gabor F. Lectin-mediated drug delivery: influence of mucin on cytoadhesion of plant lectins in vitro. J. Control. Release. 79:2002;183-191.
    • (2002) J. Control. Release , vol.79 , pp. 183-191
    • Wirth, M.1    Gerhardt, K.2    Wurm, C.3    Gabor, F.4
  • 63
    • 0037177459 scopus 로고    scopus 로고
    • Lectin-mediated drug delivery: Binding and uptake of BSA-WGA conjugates using the Caco-2 model
    • Gabor F., Schwarzbauer A., Wirth M. Lectin-mediated drug delivery: binding and uptake of BSA-WGA conjugates using the Caco-2 model. Int. J. Pharm. 237:2002;227-239.
    • (2002) Int. J. Pharm. , vol.237 , pp. 227-239
    • Gabor, F.1    Schwarzbauer, A.2    Wirth, M.3
  • 64
    • 0031830601 scopus 로고    scopus 로고
    • Polyacrylamide-based glycoconjugates as tools in glycobiology
    • Bovin N.V. Polyacrylamide-based glycoconjugates as tools in glycobiology. Glycoconjug. J. 15:1998;431-446.
    • (1998) Glycoconjug. J. , vol.15 , pp. 431-446
    • Bovin, N.V.1
  • 65
    • 0038842631 scopus 로고    scopus 로고
    • Neoglycoconjugates: Trade and art
    • Bovin N.V. Neoglycoconjugates: trade and art. Biochem. Soc. Symp. 69:2002;143-160.
    • (2002) Biochem. Soc. Symp. , vol.69 , pp. 143-160
    • Bovin, N.V.1
  • 67
    • 0033043158 scopus 로고    scopus 로고
    • A simple synthesis of 8-(methoxycarbonyl)octyl 3,6-di-O-(alpha-D- mannopyranosyl)-alpha-D-mannopyranoside and derivatives and their use in the preparation of neoglycoconjugates
    • Becker B., Furneaux R.H., Reck F., Zubkov O.A. A simple synthesis of 8-(methoxycarbonyl)octyl 3,6-di-O-(alpha-D-mannopyranosyl)-alpha-D- mannopyranoside and derivatives and their use in the preparation of neoglycoconjugates. Carbohydr. Res. 315:1999;148-158.
    • (1999) Carbohydr. Res. , vol.315 , pp. 148-158
    • Becker, B.1    Furneaux, R.H.2    Reck, F.3    Zubkov, O.A.4
  • 68
    • 0036376447 scopus 로고    scopus 로고
    • A novel strategy for the synthesis of neoglycoconjugates from deacylated deep rough lipopolysaccharides
    • Muller-Loennies S., Grimmecke D., Brade L., Lindner B., Kosma P., Brade H.J. A novel strategy for the synthesis of neoglycoconjugates from deacylated deep rough lipopolysaccharides. Endotoxin Res. 8:2002;295-305.
    • (2002) Endotoxin Res. , vol.8 , pp. 295-305
    • Muller-Loennies, S.1    Grimmecke, D.2    Brade, L.3    Lindner, B.4    Kosma, P.5    Brade, H.J.6
  • 69
    • 0036181219 scopus 로고    scopus 로고
    • Design and synthesis of glycodendrimers
    • Turnbull W.B., Stoddart J.F. Design and synthesis of glycodendrimers. J. Biotechnol. 90:2002;231-255.
    • (2002) J. Biotechnol. , vol.90 , pp. 231-255
    • Turnbull, W.B.1    Stoddart, J.F.2
  • 70
    • 0035114639 scopus 로고    scopus 로고
    • Receptor-mediated gene delivery to HepG2 cells by ternary assemblies containing cationic liposomes and cationized asialoorosomucoid
    • Singh M., Kisoon N., Ariatti M. Receptor-mediated gene delivery to HepG2 cells by ternary assemblies containing cationic liposomes and cationized asialoorosomucoid. Drug Deliv. 8:2001;29-34.
    • (2001) Drug Deliv. , vol.8 , pp. 29-34
    • Singh, M.1    Kisoon, N.2    Ariatti, M.3
  • 71
    • 0032711921 scopus 로고    scopus 로고
    • Lectin-mediated transport of nanoparticles across Caco-2 and OK cells
    • Russell-Jones G.I., Veitch H., Arthur L. Lectin-mediated transport of nanoparticles across Caco-2 and OK cells. Int. J. Pharm. 190:1999;165-174.
    • (1999) Int. J. Pharm. , vol.190 , pp. 165-174
    • Russell-Jones, G.I.1    Veitch, H.2    Arthur, L.3
  • 73
    • 0033866552 scopus 로고    scopus 로고
    • Lectin-mediated bioadhesion: Preparation, stability and caco-2 binding of wheat germ agglutinin-functionalized poly(D,L-lactic-co-glycolic acid)-microspheres
    • Ertl B., Heigl F., Wirth M., Gabor F. Lectin-mediated bioadhesion: preparation, stability and caco-2 binding of wheat germ agglutinin- functionalized poly(D,L-lactic-co-glycolic acid)-microspheres. J. Drug Targeting. 8:2000;173-184.
    • (2000) J. Drug Targeting , vol.8 , pp. 173-184
    • Ertl, B.1    Heigl, F.2    Wirth, M.3    Gabor, F.4
  • 76
    • 0035000656 scopus 로고    scopus 로고
    • Expression of endogenous lectins (galectins, receptors for ABH-epitopes) and the MIB-1 antigen in esophageal carcinomas and their syntactic structure analysis in relation to post-surgical tumor stage and lymph node involvement
    • Kayser K., Hauck E., Andre S., Bovin N.V., Kaltner H., Banach L., Lancaster E., Gabius H.J. Expression of endogenous lectins (galectins, receptors for ABH-epitopes) and the MIB-1 antigen in esophageal carcinomas and their syntactic structure analysis in relation to post-surgical tumor stage and lymph node involvement. Anticancer Res. 21:2001;1439-1444.
    • (2001) Anticancer Res. , vol.21 , pp. 1439-1444
    • Kayser, K.1    Hauck, E.2    Andre, S.3    Bovin, N.V.4    Kaltner, H.5    Banach, L.6    Lancaster, E.7    Gabius, H.J.8
  • 77
    • 0036340576 scopus 로고    scopus 로고
    • Primary colorectal carcinomas and their intrapulmonary metastases: Clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival
    • Kayser K., Zink S., Andre S., Schuring M.P., Hecker E., Klar E., Bovin N.V., Kaltner H., Gabius H.J. Primary colorectal carcinomas and their intrapulmonary metastases: clinical, glyco-, immuno- and lectin histochemical, nuclear and syntactic structure analysis with emphasis on correlation with period of occurrence of metastases and survival. APMIS. 110:2002;435-446.
    • (2002) APMIS , vol.110 , pp. 435-446
    • Kayser, K.1    Zink, S.2    Andre, S.3    Schuring, M.P.4    Hecker, E.5    Klar, E.6    Bovin, N.V.7    Kaltner, H.8    Gabius, H.J.9
  • 79
    • 0027945617 scopus 로고
    • Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate
    • Ohannesian D.W., Lotan D., Lotan R. Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate. Cancer Res. 54:1994;5992-6000.
    • (1994) Cancer Res. , vol.54 , pp. 5992-6000
    • Ohannesian, D.W.1    Lotan, D.2    Lotan, R.3
  • 81
    • 0031979352 scopus 로고    scopus 로고
    • Detection of a potential receptor for the H-blood-group antigen on rat colon carcinoma cells and normal tissues
    • Galanina O., Hallouin F., Goupille C., Bovin N., Le Pendu J. Detection of a potential receptor for the H-blood-group antigen on rat colon carcinoma cells and normal tissues. Int. J. Cancer. 76:1998;136-140.
    • (1998) Int. J. Cancer , vol.76 , pp. 136-140
    • Galanina, O.1    Hallouin, F.2    Goupille, C.3    Bovin, N.4    Le Pendu, J.5
  • 82
    • 0036690721 scopus 로고    scopus 로고
    • The role of galactose, lactose, and galactose valency in the biorecognition of N-(2-hydroxypropyl)methacrylamide copolymers by human colon adenocarcinoma cells
    • David A., Kopeckova P., Kopecek J., Rubinstein A. The role of galactose, lactose, and galactose valency in the biorecognition of N-(2-hydroxypropyl) methacrylamide copolymers by human colon adenocarcinoma cells. Pharm. Res. 19:2002;1114-1122.
    • (2002) Pharm. Res. , vol.19 , pp. 1114-1122
    • David, A.1    Kopeckova, P.2    Kopecek, J.3    Rubinstein, A.4
  • 83
    • 0033200301 scopus 로고    scopus 로고
    • Synthesis and selective cytotoxicity of a hyaluronic acid-antitumor bioconjugate
    • Luo Y., Prestwich G.D. Synthesis and selective cytotoxicity of a hyaluronic acid-antitumor bioconjugate. Bioconjug. Chem. 10:1999;755-763.
    • (1999) Bioconjug. Chem. , vol.10 , pp. 755-763
    • Luo, Y.1    Prestwich, G.D.2
  • 84
    • 0036115512 scopus 로고    scopus 로고
    • Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates
    • Luo Y., Bernshaw N.J., Lu Z.R., Kopecek J., Prestwich G.D. Targeted delivery of doxorubicin by HPMA copolymer-hyaluronan bioconjugates. Pharm. Res. 19:2002;396-402.
    • (2002) Pharm. Res. , vol.19 , pp. 396-402
    • Luo, Y.1    Bernshaw, N.J.2    Lu, Z.R.3    Kopecek, J.4    Prestwich, G.D.5
  • 85
    • 0033582313 scopus 로고    scopus 로고
    • Antitumor activity of mannan-binding protein in vivo as revealed by a virus expression system: Mannan-binding proteindependent cell-mediated cytotoxicity
    • Ma Y., Uemura K., Oka S., Kozutsumi Y., Kawasaki N., Kawasaki T. Antitumor activity of mannan-binding protein in vivo as revealed by a virus expression system: mannan-binding proteindependent cell-mediated cytotoxicity. Proc. Natl. Acad. Sci. USA. 96:1999;371-375.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 371-375
    • Ma, Y.1    Uemura, K.2    Oka, S.3    Kozutsumi, Y.4    Kawasaki, N.5    Kawasaki, T.6
  • 86
    • 0023691218 scopus 로고    scopus 로고
    • Polysaccharide-anchored immunoliposomes bearing anti-CEA Fab' fragment and their internalization by CEA-producing tumor cells
    • Sato T., Sunamoto J., Ishii N., Koji T. Polysaccharide-anchored immunoliposomes bearing anti-CEA Fab' fragment and their internalization by CEA-producing tumor cells. J. Bioact. Compat. Polym. 3:1998;196-204.
    • (1998) J. Bioact. Compat. Polym. , vol.3 , pp. 196-204
    • Sato, T.1    Sunamoto, J.2    Ishii, N.3    Koji, T.4
  • 87
    • 0038015452 scopus 로고    scopus 로고
    • Targeted proapoptotic LHRH-BH3 peptide
    • Dharap S.S., Minko T. Targeted proapoptotic LHRH-BH3 peptide. Pharm. Res. 20:2003;889-896.
    • (2003) Pharm. Res. , vol.20 , pp. 889-896
    • Dharap, S.S.1    Minko, T.2
  • 88
    • 0034049291 scopus 로고    scopus 로고
    • Efficacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma
    • Minko T., Kopeckova P., Kopecek J. Efficacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma. Int. J. Cancer. 86:2000;108-117.
    • (2000) Int. J. Cancer , vol.86 , pp. 108-117
    • Minko, T.1    Kopeckova, P.2    Kopecek, J.3
  • 89
    • 0038377441 scopus 로고    scopus 로고
    • Enhancing the efficacy of chemotherapeutic drugs by the suppression of antiapoptotic cellular defense
    • Minko T., Dharap S.S., Fabbricatore A.T., Enhancing the efficacy of chemotherapeutic drugs by the suppression of antiapoptotic cellular defense. Cancer Detect. Prev. 27:2003;194-202.
    • (2003) Cancer Detect. Prev. , vol.27 , pp. 194-202
    • Minko, T.1    Dharap, S.S.2    Fabbricatore, A.T.3
  • 90
    • 0037336279 scopus 로고    scopus 로고
    • Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin
    • Pakunlu R.I., Cook T.J., Minko T. Simultaneous modulation of multidrug resistance and antiapoptotic cellular defense by MDR1 and BCL-2 targeted antisense oligonucleotides enhances the anticancer efficacy of doxorubicin. Pharm. Res. 20:2003;351-359.
    • (2003) Pharm. Res. , vol.20 , pp. 351-359
    • Pakunlu, R.I.1    Cook, T.J.2    Minko, T.3
  • 91
    • 0038287139 scopus 로고    scopus 로고
    • Enhancing the efficacy of anticancer drugs using complex multicomponent advanced drug delivery systems
    • Minko T. Enhancing the efficacy of anticancer drugs using complex multicomponent advanced drug delivery systems. Business Briefing: Future Drug Discov. 12:2001;134-136.
    • (2001) Business Briefing: Future Drug Discov. , vol.12 , pp. 134-136
    • Minko, T.1
  • 92
    • 0033179760 scopus 로고    scopus 로고
    • BCL-2 family members and the mitochondria in apoptosis
    • Gross A., McDonnell J.M., Korsmeyer S. BCL-2 family members and the mitochondria in apoptosis. Genes Dev. 13:1999;1899-1911.
    • (1999) Genes Dev. , vol.13 , pp. 1899-1911
    • Gross, A.1    McDonnell, J.M.2    Korsmeyer, S.3
  • 93
    • 0032877668 scopus 로고    scopus 로고
    • Dysregulation of apoptosis in cancer
    • Reed J. Dysregulation of apoptosis in cancer. J. Clin. Oncol. 17:1999;2941-2953.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 2941-2953
    • Reed, J.1
  • 94
    • 0034307013 scopus 로고    scopus 로고
    • Molecular genetics of prostate cancer
    • Abate-Shen C., Shen M.M. Molecular genetics of prostate cancer. Genes Dev. 14:2000;2410-2434.
    • (2000) Genes Dev. , vol.14 , pp. 2410-2434
    • Abate-Shen, C.1    Shen, M.M.2
  • 95
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai Z.N., Milliman C.L., Korsmeyer S.J. Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell. 74:1993;609-619.
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 96
    • 0034057320 scopus 로고    scopus 로고
    • Apoptosis in cancer
    • Lowe S.W., Lin A.W. Apoptosis in cancer. Carcinogenesis. 21:2000;485-495.
    • (2000) Carcinogenesis , vol.21 , pp. 485-495
    • Lowe, S.W.1    Lin, A.W.2
  • 99
    • 0033305471 scopus 로고    scopus 로고
    • Editorial: Mcl-1 - Just another antiapoptotic BCL-2 homolog?
    • Johnson A.L. Editorial: Mcl-1 - just another antiapoptotic BCL-2 homolog? Endocrinology. 140:1999;5465-5467.
    • (1999) Endocrinology , vol.140 , pp. 5465-5467
    • Johnson, A.L.1
  • 100
    • 0033965412 scopus 로고    scopus 로고
    • Role of the BH3 (BCL-2 homology 3) domain in the regulation of apoptosis and BCL-2-related proteins
    • Lutz R.J. Role of the BH3 (BCL-2 homology 3) domain in the regulation of apoptosis and BCL-2-related proteins. Biochem. Sci. Trans. 28:(Part 2):2000;51-56.
    • (2000) Biochem. Sci. Trans. , vol.28 , Issue.PART 2 , pp. 51-56
    • Lutz, R.J.1
  • 101
    • 0033531926 scopus 로고    scopus 로고
    • Bak BH3 peptides antagonize BCL-XL functions and induce apoptosis through cytochrome c-independent activation of caspases
    • Holinger E., Chittenden T., Lutz R.J. Bak BH3 peptides antagonize BCL-XL functions and induce apoptosis through cytochrome c-independent activation of caspases. J. Biol. Chem. 274:1999;13298-13304.
    • (1999) J. Biol. Chem. , vol.274 , pp. 13298-13304
    • Holinger, E.1    Chittenden, T.2    Lutz, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.