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Volumn 17, Issue 2, 1999, Pages 478-484

Randomized phase II study of BR96-doxorubicin conjugate in patients with metastatic breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY CONJUGATE; BMS 182248 1; DOXORUBICIN; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

EID: 0032975042     PISSN: 0732183X     EISSN: None     Source Type: Journal    
DOI: 10.1200/jco.1999.17.2.478     Document Type: Article
Times cited : (246)

References (11)
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    • Trail PA, Willner D, Lasch SJ, et al: Cure of xenografted human carcinomas by BR96-doxorubicin immunoconjugates [published erratum appears in Science 263:1076, 1994]. Science 261:212-215, 1993
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    • Trail, P.A.1    Willner, D.2    Lasch, S.J.3
  • 2
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    • Ley specific antibody with potent anti-tumor activity is internalized and degraded in lysosomes
    • Garrigues J, Garrigues U, Hellstrom I, et al: Ley specific antibody with potent anti-tumor activity is internalized and degraded in lysosomes. Am J Pathol 142:607-622, 1993
    • (1993) Am J Pathol , vol.142 , pp. 607-622
    • Garrigues, J.1    Garrigues, U.2    Hellstrom, I.3
  • 3
    • 0025218791 scopus 로고
    • Highly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(Y)-related cell surface antigens
    • Hellstrom I, Garrigues HJ, Garrigues U, et al: Highly tumor-reactive, internalizing, mouse monoclonal antibodies to Le(Y)-related cell surface antigens. Cancer Res 50:2183-2190, 1990
    • (1990) Cancer Res , vol.50 , pp. 2183-2190
    • Hellstrom, I.1    Garrigues, H.J.2    Garrigues, U.3
  • 4
    • 1842369073 scopus 로고    scopus 로고
    • Antitumor activity of carcinoma-reactive BR96-doxorubicin conjugate against human carcinomas in athymic mice and rats and syngeneic rat carcinomas in immunocompetent rats
    • Sjogren HO, Isaksson M, Willner D, et al: Antitumor activity of carcinoma-reactive BR96-doxorubicin conjugate against human carcinomas in athymic mice and rats and syngeneic rat carcinomas in immunocompetent rats. Cancer Res 57:4530-4536, 1997
    • (1997) Cancer Res , vol.57 , pp. 4530-4536
    • Sjogren, H.O.1    Isaksson, M.2    Willner, D.3
  • 5
    • 0028608897 scopus 로고
    • BR96-doxorubicin conjugate (BMS-182248) versus doxorubicin: A comparative toxicity assessment in rats
    • Comereski CR, Peden WM, Davidson TJ, et al: BR96-doxorubicin conjugate (BMS-182248) versus doxorubicin: A comparative toxicity assessment in rats. Toxicol Pathol 22:473-488, 1994
    • (1994) Toxicol Pathol , vol.22 , pp. 473-488
    • Comereski, C.R.1    Peden, W.M.2    Davidson, T.J.3
  • 6
    • 84871473893 scopus 로고
    • Gastrointestinal effects of chimeric BR96-doxorubicin (DOX) conjugate
    • abstr
    • Saleh M, LoBuglio A, Sugarman S, et al: Gastrointestinal effects of chimeric BR96-doxorubicin (DOX) conjugate. Proc Am Assoc Cancer Res 36:A2876, 1995 (abstr)
    • (1995) Proc Am Assoc Cancer Res , vol.36
    • Saleh, M.1    LoBuglio, A.2    Sugarman, S.3
  • 7
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    • A phase I study of BR96-doxorubicin (BR96-Dox) in patients with advanced carcinoma expressing the Lewis(Y) antigen
    • abstr
    • Sugarman S, Murray JL, Saleh M, et al: A phase I study of BR96-doxorubicin (BR96-Dox) in patients with advanced carcinoma expressing the Lewis(Y) antigen. Proc Am Soc Clin Oncol 14:A1532, 1995 (abstr)
    • (1995) Proc Am Soc Clin Oncol , vol.14
    • Sugarman, S.1    Murray, J.L.2    Saleh, M.3
  • 8
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    • Phase I studies of BR96 doxorubicin in patients with advanced solid tumors that express the Lewis Y antigen
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    • Slichenmyer WJ, Saleh MN, Bookman MA, et al: Phase I studies of BR96 doxorubicin in patients with advanced solid tumors that express the Lewis Y antigen. Anti-Cancer Treatment, Sixth International Congress, 1996, pp 95:6-9, (abstr)
    • (1996) Anti-cancer Treatment, Sixth International Congress , pp. 95
    • Slichenmyer, W.J.1    Saleh, M.N.2    Bookman, M.A.3
  • 9
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  • 10
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  • 11
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    • (1998) Monoclonal Antibody-based Therapy of Cancer , pp. 397-416
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.