Lipid nanoparticles protect from edelfosine toxicity in vivo

International Journal of Pharmaceutics

Volumn 474, Issue 1-2, 2014, Pages 1-5

  Lasa Saracíbar, Beatriz ^a   Aznar, María Ángela ^a   Lana, Hugo ^a   Aizpún, Ismael ^a   Gil, Ana Gloria ^a   Blanco Prieto, Maria J ^a  

^a UNIVERSITY OF NAVARRA   (Spain)

Author keywords

Alkyl lysophospholipids; Edelfosine; In vivo; Lipid nanoparticles; Toxicity

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ASPARTATE AMINOTRANSFERASE; CREATININE; EDELFOSINE; HEMOGLOBIN; LIPID NANOPARTICLE; NANOPARTICLE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; UREA; ETHER PHOSPHOLIPID; IMMUNOSUPPRESSIVE AGENT; LIPID;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL DEATH; CELL DEGENERATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEATH; DRUG DELIVERY SYSTEM; DRUG SAFETY; DRUG TOXICITY; ERYTHROCYTE COUNT; FEMALE; GASTROINTESTINAL OBSTRUCTION; GASTROINTESTINAL TOXICITY; HEART; HEMATOCRIT; HISTOPATHOLOGY; IMMUNE DEFICIENCY; IN VIVO STUDY; KIDNEY; LEUKOCYTE COUNT; LIVER; MALE; MOUSE; MOUSE MODEL; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PROTECTION; SMALL INTESTINE; SPLEEN; STOMACH; THROMBOCYTE COUNT; UREA BLOOD LEVEL; ZETA POTENTIAL; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; CHEMICALLY INDUCED; CHEMISTRY; DOSE RESPONSE; GASTROINTESTINAL DISEASES; ORAL DRUG ADMINISTRATION; PATHOLOGY;

ADMINISTRATION, ORAL; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GASTROINTESTINAL DISEASES; IMMUNOSUPPRESSIVE AGENTS; LIPIDS; MALE; MICE; MICE, INBRED BALB C; NANOPARTICLES; PHOSPHOLIPID ETHERS;

EID: 84905815119     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.07.053     Document Type: Article

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