Carboxymethylcellulose-tetrahydrocurcumin conjugates for colon-specific delivery of a novel anti-cancer agent, 4-amino tetrahydrocurcumin

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 88, Issue 2, 2014, Pages 351-360

  Plyduang, Thipapun ^a   Lomlim, Luelak ^a   Yuenyongsawad, Supreeya ^a   Wiwattanapatapee, Ruedeekorn ^a  

^a PRINCE OF SONGKLA UNIVERSITY   (Thailand)

Author keywords

Carboxymethylcellulose; Colon specific drug delivery; Colonic cancer; Cytotoxic ability; Polymer conjugates; Tetrahydrocurcumin

Indexed keywords

4 AMINO TETRAHYDROCURCUMIN; 4 AMINOBENZOIC ACID; 4 AMINOHIPPURIC ACID; ANTINEOPLASTIC AGENT; AZO REDUCTASE; CARBOXYMETHYLCELLULOSE; CURCUMIN; POLYCYCLIC AROMATIC HYDROCARBON; POLYMER; PRODRUG; UNCLASSIFIED DRUG; WATER; TETRAHYDROCURCUMIN;

ANIMAL TISSUE; ARTICLE; AZO BOND; CANCER CELL LINE; CELL VIABILITY; COLON ADENOCARCINOMA; COLON FLORA; COLON SPECIFIC DRUG DELIVERY SYSTEM; CONTROLLED STUDY; COVALENT BOND; CYTOTOXICITY; DIAZOTIZATION; DOWN REGULATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG STABILITY; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HYDROGEN BOND; IC50; MACROMOLECULE; NONHUMAN; PH; RAT; SOLUBILITY; STEREOSPECIFICITY; SUSTAINED DRUG RELEASE; UPREGULATION; WATER SOLUBILITY; ANALOGS AND DERIVATIVES; CHEMISTRY; COLON; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROPHOTOMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CARBOXYMETHYLCELLULOSE SODIUM; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLON; CURCUMIN; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; SOLUBILITY; SPECTROPHOTOMETRY, INFRARED;

EID: 84908368867     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2014.05.011     Document Type: Article

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