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Volumn 27, Issue 7, 2010, Pages 232-246

Multifunctionality of lipid-core micelles for drug delivery and tumour targeting

Author keywords

cancer targeting; Phospholipid micelles; stimuli sensitive nanocarriers

Indexed keywords

CAMPTOTHECIN; CISPLATIN; CLONAZEPAM; DEQUALINIUM; DEXTRAN B POLY(EPSILON CAPROLACTONE)DIBLOCK COPOLYMER; DOXORUBICIN; EPIRUBICIN; GRISEOFULVIN; HALOPERIDOL; IBUPROFEN; INDOMETACIN; L 685818; MACROGOL; MENADIONE; NANOCARRIER; PACLITAXEL; POLOXAMER; POLY(BETA BENZYL L ASPARTATE)B POLYETHYLENEGLYCOL; POLY(D,L LACTIDE)B METHOXY POLYETHYLENEGLYCOL; POLY(GAMMA BENZYL L GLUTAMATE)B POLYETHYLENEGLYCOL; POLY(L LYSINE)B POLYETHYLENEGLYCOL; POLY(N ISOPROPYLACRYLAMIDE)B POLYETHYLENEGLYCOL; POLY(N VINYL 2 PYRROLIDONE)B POLY(D,L LACTIDE); POLYCAPROLACTONE B METHOXY POLYETHYLENEGLYCOL; POLYCARPROLACTONE B POLYETHYLENEGLYCOL; POLYETHYLENEGLYCOL B POLY(LACTIC CO GLYCOLIC ACID); POLYETHYLENEGLYCOL PHOSPHATIDYLETHANOLAMINE; PORPHYRIN; TACROLIMUS; TESTOSTERONE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 78049341053     PISSN: 09687688     EISSN: 14645203     Source Type: Journal    
DOI: 10.3109/09687688.2010.516276     Document Type: Review
Times cited : (89)

References (126)
  • 1
    • 0030111359 scopus 로고    scopus 로고
    • Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer
    • Alakhov V, Moskaleva E, Batrakova EV, Kabanov AV. 1996. Hypersensitization of multidrug resistant human ovarian carcinoma cells by pluronic P85 block copolymer. Bioconjug Chem 7:209-216.
    • (1996) Bioconjug Chem , vol.7 , pp. 209-216
    • Alakhov, V.1    Moskaleva, E.2    Batrakova, E.V.3    Kabanov, A.V.4
  • 2
    • 0031656495 scopus 로고    scopus 로고
    • Block copolymeric biotransport carriers as versatile vehicles for drug delivery
    • Alakhov VY, Kabanov AV. 1998. Block copolymeric biotransport carriers as versatile vehicles for drug delivery. Expert Opin Investig Drugs 7:1453-1473.
    • (1998) Expert Opin Investig Drugs , vol.7 , pp. 1453-1473
    • Alakhov, V.Y.1    Kabanov, A.V.2
  • 3
    • 0032170975 scopus 로고    scopus 로고
    • Polycaprolactone-b-poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818
    • Allen C, Yu Y, Maysinger D, Eisenberg A. 1998. Polycaprolactone-b- poly(ethylene oxide) block copolymer micelles as a novel drug delivery vehicle for neurotrophic agents FK506 and L-685,818. Bioconjug Chem 9:564-572.
    • (1998) Bioconjug Chem , vol.9 , pp. 564-572
    • Allen, C.1    Yu, Y.2    Maysinger, D.3    Eisenberg, A.4
  • 4
    • 23944513297 scopus 로고    scopus 로고
    • Dendrimeric micelles for controlled drug release and targeted delivery
    • Ambade AV, Savariar EN, Thayumanavan S. 2005. Dendrimeric micelles for controlled drug release and targeted delivery. Mol Pharm 2:264-272.
    • (2005) Mol Pharm , vol.2 , pp. 264-272
    • Ambade, A.V.1    Savariar, E.N.2    Thayumanavan, S.3
  • 5
    • 16344390189 scopus 로고    scopus 로고
    • Formation of core-shell type biodegradable polymeric micelles from amphiphilic poly(aspar-tic acid)-block-polylactide diblock copolymer
    • Arimura H, Ohya Y, Ouchi T. 2005. Formation of core-shell type biodegradable polymeric micelles from amphiphilic poly(aspar-tic acid)-block-polylactide diblock copolymer. Biomacromole-cules 6:720-725.
    • (2005) Biomacromole-cules , vol.6 , pp. 720-725
    • Arimura, H.1    Ohya, Y.2    Ouchi, T.3
  • 6
    • 0036298282 scopus 로고    scopus 로고
    • Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions
    • Astriab-Fisher A, Sergueev D, Fisher M, Shaw BR, Juliano RL. 2002.Conjugates of antisense oligonucleotides with the Tat and antennapedia cell-penetrating peptides: Effects on cellular uptake, binding to target sequences, and biologic actions. Pharm Res 19:744-754.
    • (2002) Pharm Res , vol.19 , pp. 744-754
    • Astriab-Fisher, A.1    Sergueev, D.2    Fisher, M.3    Shaw, B.R.4    Juliano, R.L.5
  • 7
    • 67649229657 scopus 로고    scopus 로고
    • Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copo-lymers
    • Bae Y, Kataoka K. 2009. Intelligent polymeric micelles from functional poly(ethylene glycol)-poly(amino acid) block copo-lymers. Adv Drug Deliv Rev 61:768-784.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 768-784
    • Bae, Y.1    Kataoka, K.2
  • 8
    • 34548267667 scopus 로고    scopus 로고
    • Endocytic mechanisms for targeted drug delivery
    • Bareford LM, Swaan PW. 2007. Endocytic mechanisms for targeted drug delivery. Adv Drug Deliv Rev 59:748-758.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 748-758
    • Bareford, L.M.1    Swaan, P.W.2
  • 10
    • 0034950084 scopus 로고    scopus 로고
    • Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl-2-pyrrolidone)-block-poly(D,L-lactide)
    • Benahmed A, Ranger M, Leroux JC. 2001. Novel polymeric micelles based on the amphiphilic diblock copolymer poly(N-vinyl-2-pyrrolidone)-block-poly(D,L- lactide). Pharm Res 18: 323-328.
    • (2001) Pharm Res , vol.18 , pp. 323-328
    • Benahmed, A.1    Ranger, M.2    Leroux, J.C.3
  • 11
    • 0036888314 scopus 로고    scopus 로고
    • K vitamins, PTP antagonism, and cell growth arrest
    • Carr BI, Wang Z, Kar S. 2002. K vitamins, PTP antagonism, and cell growth arrest. J Cell Physiol 193:263-274.
    • (2002) J Cell Physiol , vol.193 , pp. 263-274
    • Carr, B.I.1    Wang, Z.2    Kar, S.3
  • 12
    • 0001453781 scopus 로고
    • Effect of block size and sequence on the micellization of ABC triblock methacrylic acid polyampholytes
    • Chen W-Y, Su C-K, Patrickios CS, Hertler WR, Hatton TA. 1995. Effect of block size and sequence on the micellization of ABC triblock methacrylic acid polyampholytes. Macromolecules 28:8604-8611.
    • (1995) Macromolecules , vol.28 , pp. 8604-8611
    • Chen, W.-Y.1    Su, C.-K.2    Patrickios, C.S.3    Hertler, W.R.4    Hatton, T.A.5
  • 13
    • 0038064275 scopus 로고    scopus 로고
    • Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(epsilon- caprolactone) copolymer as a carrier for paclitaxel
    • Cheon Lee S, Kim C, Chan Kwon I, Chung H, Young Jeong S. 2003.Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(epsilon-caprolactone) copolymer as a carrier for paclitaxel. J Control Release 89:437-446.
    • (2003) J Control Release , vol.89 , pp. 437-446
    • Cheon Lee, S.1    Kim, C.2    Chan Kwon, I.3    Chung, H.4    Young Jeong, S.5
  • 14
    • 0032580492 scopus 로고    scopus 로고
    • Effect of molecular architecture of hydrophobically modified poly(N-isopropylacrylamide) on the formation of thermore-sponsive core-shell micellar drug carriers
    • Chung JE, Yokoyama M, Aoyagi T, Sakurai Y, Okano T. 1998. Effect of molecular architecture of hydrophobically modified poly(N-isopropylacrylamide) on the formation of thermore-sponsive core-shell micellar drug carriers. J Control Release 53:119-130.
    • (1998) J Control Release , vol.53 , pp. 119-130
    • Chung, J.E.1    Yokoyama, M.2    Aoyagi, T.3    Sakurai, Y.4    Okano, T.5
  • 15
    • 0032875798 scopus 로고    scopus 로고
    • Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate)
    • Chung JE, Yokoyama M, Yamato M, Aoyagi T, Sakurai Y, Okano T. 1999. Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate). J Control Release 62:115-127.
    • (1999) J Control Release , vol.62 , pp. 115-127
    • Chung, J.E.1    Yokoyama, M.2    Yamato, M.3    Aoyagi, T.4    Sakurai, Y.5    Okano, T.6
  • 16
    • 0037422066 scopus 로고    scopus 로고
    • Regulated portals of entry into the cell
    • Conner SD, Schmid SL. 2003. Regulated portals of entry into the cell. Nature 422:37-44.
    • (2003) Nature , vol.422 , pp. 37-44
    • Conner, S.D.1    Schmid, S.L.2
  • 17
    • 33646367645 scopus 로고    scopus 로고
    • Polyethylene glycol-phosphatidylethanola-mine conjugate (PEG-PE)-based mixed micelles: Some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux
    • Dabholkar RD, Sawant RM, Mongayt DA, Devarajan PV, Torchilin VP. 2006. Polyethylene glycol-phosphatidylethanola-mine conjugate (PEG-PE)-based mixed micelles: Some properties, loading with paclitaxel, and modulation of P-glycoprotein-mediated efflux. Int J Pharm 315:148-157.
    • (2006) Int J Pharm , vol.315 , pp. 148-157
    • Dabholkar, R.D.1    Sawant, R.M.2    Mongayt, D.A.3    Devarajan, P.V.4    Torchilin, V.P.5
  • 18
    • 17644416726 scopus 로고    scopus 로고
    • Polymeric micelles based on amphiphilic scorpion-like macromolecules: Novel carriers for water-insoluble drugs
    • Djordjevic J, Barch M, Uhrich KE. 2005. Polymeric micelles based on amphiphilic scorpion-like macromolecules: Novel carriers for water-insoluble drugs. Pharm Res 22:24-32.
    • (2005) Pharm Res , vol.22 , pp. 24-32
    • Djordjevic, J.1    Barch, M.2    Uhrich, K.E.3
  • 19
    • 2442713629 scopus 로고    scopus 로고
    • Preparation and characterization of water-soluble pH-sensitive nanocarriers for drug delivery
    • Dufresne MH, Garrec DL, Sant V, Leroux JC, Ranger M. 2004. Preparation and characterization of water-soluble pH-sensitive nanocarriers for drug delivery. Int J Pharm 277:81-90.
    • (2004) Int J Pharm , vol.277 , pp. 81-90
    • Dufresne, M.H.1    Garrec, D.L.2    Sant, V.3    Leroux, J.C.4    Ranger, M.5
  • 20
    • 76249103637 scopus 로고    scopus 로고
    • Multifunctional block copolymer micelles for the delivery of 111In to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy
    • Fonge H, Lee H, Reilly RM, Allen C. 2010. Multifunctional block copolymer micelles for the delivery of 111In to EGFR-positive breast cancer cells for targeted Auger electron radiotherapy. Mol Pharm 7:177-186.
    • (2010) Mol Pharm , vol.7 , pp. 177-186
    • Fonge, H.1    Lee, H.2    Reilly, R.M.3    Allen, C.4
  • 21
    • 29244477993 scopus 로고    scopus 로고
    • In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles
    • Forrest ML, Won CY, Malick AW, Kwon GS. 2006. In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles. J Control Release 110:370-377.
    • (2006) J Control Release , vol.110 , pp. 370-377
    • Forrest, M.L.1    Won, C.Y.2    Malick, A.W.3    Kwon, G.S.4
  • 23
    • 0029360317 scopus 로고
    • Liposome circulation time and tumor targeting: Implications for cancer chemotherapy
    • Gabizon AA. 1995. Liposome circulation time and tumor targeting: Implications for cancer chemotherapy. Adv Drug Deliv Rev 16:285-294.
    • (1995) Adv Drug Deliv Rev , vol.16 , pp. 285-294
    • Gabizon, A.A.1
  • 24
    • 33646713939 scopus 로고    scopus 로고
    • Conjugates of poly(DL-lactic acid) with ethylenediamino or diethylenetriamino bridged bis(beta-cyclodextrin)s and their nanoparticles as protein delivery systems
    • Gao H, Yang YW, Fan YG, Ma JB. 2006. Conjugates of poly(DL-lactic acid) with ethylenediamino or diethylenetriamino bridged bis(beta-cyclodextrin)s and their nanoparticles as protein delivery systems. J Control Release 112:301-311.
    • (2006) J Control Release , vol.112 , pp. 301-311
    • Gao, H.1    Yang, Y.W.2    Fan, Y.G.3    Ma, J.B.4
  • 25
    • 0038268753 scopus 로고    scopus 로고
    • PEG-PE/ phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing
    • GaoZ, Lukyanov AN, Chakilam AR, Torchilin VP. 2003. PEG-PE/ phosphatidylcholine mixed immunomicelles specifically deliver encapsulated taxol to tumor cells of different origin and promote their efficient killing. J Drug Target 11:87-92.
    • (2003) J Drug Target , vol.11 , pp. 87-92
    • Gaoz Lukyanov, A.N.1    Chakilam, A.R.2    Torchilin, V.P.3
  • 26
    • 0038197607 scopus 로고    scopus 로고
    • Diacyl polymer micelles as nanocarriers for poorly soluble anticancer drugs
    • Gao Z, Lukyanov AN, Singhal A, Torchilin VP. 2002. Diacyl polymer micelles as nanocarriers for poorly soluble anticancer drugs. Nano Lett 2:979-982.
    • (2002) Nano Lett , vol.2 , pp. 979-982
    • Gao, Z.1    Lukyanov, A.N.2    Singhal, A.3    Torchilin, V.P.4
  • 27
    • 0028136653 scopus 로고
    • Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques
    • Gold R, Schmied M, Giegerich G, Breitschopf H, Hartung HP, Toyka KV, Lassmann H. 1994. Differentiation between cellular apoptosis and necrosis by the combined use of in situ tailing and nick translation techniques. Lab Invest 71:219-225.
    • (1994) Lab Invest , vol.71 , pp. 219-225
    • Gold, R.1    Schmied, M.2    Giegerich, G.3    Breitschopf, H.4    Hartung, H.P.5    Toyka, K.V.6    Lassmann, H.7
  • 28
    • 0029344655 scopus 로고
    • Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly9ethylene glycol) segments
    • Harada A, Kataoka K. 1995. Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly9ethylene glycol) segments. Macro-molecules 28:5294-5299.
    • (1995) Macro-molecules , vol.28 , pp. 5294-5299
    • Harada, A.1    Kataoka, K.2
  • 30
    • 0032509929 scopus 로고    scopus 로고
    • An AB block copolymer of oligo(methyl methacrylate) and poly(acrylic acid) for micellar delivery of hydrophobic drugs
    • Inoue T, Chen G, Nakamae K, Hoffman AS. 1998. An AB block copolymer of oligo(methyl methacrylate) and poly(acrylic acid) for micellar delivery of hydrophobic drugs. J Control Release 51:221-229.
    • (1998) J Control Release , vol.51 , pp. 221-229
    • Inoue, T.1    Chen, G.2    Nakamae, K.3    Hoffman, A.S.4
  • 32
    • 18844389468 scopus 로고    scopus 로고
    • Cellular recognition of paclitaxel-loaded polymeric nano-particles composed of poly(gamma-benzyl L-glutamate) and poly(ethylene glycol) diblock copolymer endcapped with galactose moiety
    • Jeong YI, Seo SJ, Park IK, Lee HC, Kang IC, Akaike T, Cho CS. 2005.Cellular recognition of paclitaxel-loaded polymeric nano-particles composed of poly(gamma-benzyl L-glutamate) and poly(ethylene glycol) diblock copolymer endcapped with galactose moiety. Int J Pharm 296:151-161.
    • (2005) Int J Pharm , vol.296 , pp. 151-161
    • Jeong, Y.I.1    Seo, S.J.2    Park, I.K.3    Lee, H.C.4    Kang, I.C.5    Akaike, T.6    Cho, C.S.7
  • 33
    • 33646370758 scopus 로고    scopus 로고
    • Novel polymer micelles prepared from chitosan grafted hydrophobic palmitoyl groups for drug delivery
    • Jiang GB, Quan D, Liao K, Wang H. 2006. Novel polymer micelles prepared from chitosan grafted hydrophobic palmitoyl groups for drug delivery. Mol Pharm 3:152-160.
    • (2006) Mol Pharm , vol.3 , pp. 152-160
    • Jiang, G.B.1    Quan, D.2    Liao, K.3    Wang, H.4
  • 34
    • 0032778659 scopus 로고    scopus 로고
    • Polymeric micelles-a new generation of colloidal drug carriers
    • Jones M, Leroux J. 1999. Polymeric micelles-a new generation of colloidal drug carriers. Eur J Pharm Biopharm 48:101-111.
    • (1999) Eur J Pharm Biopharm , vol.48 , pp. 101-111
    • Jones, M.1    Leroux, J.2
  • 36
    • 14644411706 scopus 로고    scopus 로고
    • Prud'Homme Zhang Gaucher Leroux G Y RE ME J.C.
    • Kang N, Perron ME, Prud'homme RE, Zhang Y, Gaucher G, Leroux JC. 2005. Stereocomplex block copolymer micelles: Core-shell nanostructures with enhanced stability. Nano Lett 5:315-319.
    • (2005) Nano Lett , vol.5 , pp. 315-319
    • Kang, N.1    Perron2
  • 37
    • 0035937592 scopus 로고    scopus 로고
    • Block copolymer micelles for drug delivery: Design, characterization and biological significance
    • Kataoka K, Harada A, Nagasaki Y. 2001. Block copolymer micelles for drug delivery: Design, characterization and biological significance. Adv Drug Deliv Rev 47:113-131.
    • (2001) Adv Drug Deliv Rev , vol.47 , pp. 113-131
    • Kataoka, K.1    Harada, A.2    Nagasaki, Y.3
  • 38
    • 0033980297 scopus 로고    scopus 로고
    • Doxorubicin-loaded poly(ethylene glycol)-poly(beta-benzyl-L-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance
    • Kataoka K, Matsumoto T, Yokoyama M, Okano T, Sakurai Y, Fukushima S, Okamoto K, Kwon GS. 2000. Doxorubicin-loaded poly(ethylene glycol)-poly(beta- benzyl-L-aspartate) copolymer micelles: Their pharmaceutical characteristics and biological significance. J Control Release 64:143-153.
    • (2000) J Control Release , vol.64 , pp. 143-153
    • Kataoka, K.1    Matsumoto, T.2    Yokoyama, M.3    Okano, T.4    Sakurai, Y.5    Fukushima, S.6    Okamoto, K.7    Kwon, G.S.8
  • 39
    • 0031239718 scopus 로고    scopus 로고
    • Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer
    • Katayose S, Kataoka K. 1997. Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer. Bioconjug Chem 8:702-707.
    • (1997) Bioconjug Chem , vol.8 , pp. 702-707
    • Katayose, S.1    Kataoka, K.2
  • 40
    • 0031938986 scopus 로고    scopus 로고
    • Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer
    • Katayose S, Kataoka K. 1998. Remarkable increase in nuclease resistance of plasmid DNA through supramolecular assembly with poly(ethylene glycol)-poly(L-lysine) block copolymer. J Pharm Sci 87:160-163.
    • (1998) J Pharm Sci , vol.87 , pp. 160-163
    • Katayose, S.1    Kataoka, K.2
  • 42
    • 70350057605 scopus 로고    scopus 로고
    • In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer
    • Kim D, Gao ZG, Lee ES, Bae YH. 2009. In vivo evaluation of doxorubicin-loaded polymeric micelles targeting folate receptors and early endosomal pH in drug-resistant ovarian cancer. Mol Pharm 6:1353-1362.
    • (2009) Mol Pharm , vol.6 , pp. 1353-1362
    • Kim, D.1    Gao, Z.G.2    Lee, E.S.3    Bae, Y.H.4
  • 44
    • 2542559832 scopus 로고    scopus 로고
    • Phase i and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies
    • Kim TY, Kim DW, Chung JY, Shin SG, Kim SC, Heo DS, Kim NK, Bang YJ. 2004. Phase I and pharmacokinetic study of Genexol-PM, a cremophor-free, polymeric micelle-formulated paclitaxel, in patients with advanced malignancies. Clin Cancer Res 10:3708-3716.
    • (2004) Clin Cancer Res , vol.10 , pp. 3708-3716
    • Kim, T.Y.1    Kim, D.W.2    Chung, J.Y.3    Shin, S.G.4    Kim, S.C.5    Heo, D.S.6    Kim, N.K.7    Bang, Y.J.8
  • 46
    • 0032915634 scopus 로고    scopus 로고
    • Soluble self-assembled block copoly-mers for drug delivery
    • Kwon GS, Okano T. 1999. Soluble self-assembled block copoly-mers for drug delivery. Pharm Res 16:597-600.
    • (1999) Pharm Res , vol.16 , pp. 597-600
    • Kwon, G.S.1    Okano, T.2
  • 48
    • 0002960925 scopus 로고    scopus 로고
    • Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl L-aspartate) block copolymer micelles
    • La SB, Okano T, Kataoka K. 1996. Preparation and characterization of the micelle-forming polymeric drug indomethacin-incorporated poly(ethylene oxide)-poly(beta-benzyl L-aspartate) block copolymer micelles. J Pharm Sci 85:85-90.
    • (1996) J Pharm Sci , vol.85 , pp. 85-90
    • La, S.B.1    Okano, T.2    Kataoka, K.3
  • 50
    • 0037148656 scopus 로고    scopus 로고
    • Poly(ethylene oxide)-block-poly(L-amino acid) micelles for drug delivery
    • Lavasanifar A, Samuel J, Kwon GS. 2002. Poly(ethylene oxide)-block-poly(L-amino acid) micelles for drug delivery. Adv Drug Deliv Rev 54:169-190.
    • (2002) Adv Drug Deliv Rev , vol.54 , pp. 169-190
    • Lavasanifar, A.1    Samuel, J.2    Kwon, G.S.3
  • 51
    • 4444231342 scopus 로고    scopus 로고
    • Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydropho-bic anticancer drugs. in vitro and in vivo evaluation
    • Le Garrec D, Gori S, Luo L, Lessard D, Smith DC, Yessine MA, Ranger M, Leroux JC. 2004. Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydropho-bic anticancer drugs: In vitro and in vivo evaluation. J Control Release 99:83-101.
    • (2004) J Control Release , vol.99 , pp. 83-101
    • Le Garrec, D.1    Gori, S.2    Luo, L.3    Lessard, D.4    Smith, D.C.5    Yessine, M.A.6    Ranger, M.7    Leroux, J.C.8
  • 52
    • 0141921483 scopus 로고    scopus 로고
    • Polymeric micelle for tumor pH and folate-mediated targeting
    • Lee ES, Na K, Bae YH. 2003. Polymeric micelle for tumor pH and folate-mediated targeting. J Control Release 91:103-113.
    • (2003) J Control Release , vol.91 , pp. 103-113
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 54
    • 0034006169 scopus 로고    scopus 로고
    • Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells
    • Lewin M, Carlesso N, Tung CH, Tang XW, Cory D, Scadden DT, Weissleder R. 2000. Tat peptide-derivatized magnetic nanoparticles allow in vivo tracking and recovery of progenitor cells. Nat Biotechnol 18:410-414.
    • (2000) Nat Biotechnol , vol.18 , pp. 410-414
    • Lewin, M.1    Carlesso, N.2    Tung, C.H.3    Tang, X.W.4    Cory, D.5    Scadden, D.T.6    Weissleder, R.7
  • 55
    • 36049026548 scopus 로고    scopus 로고
    • Preparation and properties of mixed micelles made of Pluronic polymer and PEG-PE
    • Li L, Tan YB. 2008. Preparation and properties of mixed micelles made of Pluronic polymer and PEG-PE. J Colloid Interface Sci 317:326-331.
    • (2008) J Colloid Interface Sci , vol.317 , pp. 326-331
    • Li, L.1    Tan, Y.B.2
  • 56
    • 27844531961 scopus 로고    scopus 로고
    • Micelles from poly(ethylene glycol)-phosphatidyl ethanolamine conjugates (PEG-PE) as pharmaceutical nanocarriers for poorly soluble drug camptothecin
    • Li M, Chrastina A, Levchenko T, Torchilin VP. 2005. Micelles from poly(ethylene glycol)-phosphatidyl ethanolamine conjugates (PEG-PE) as pharmaceutical nanocarriers for poorly soluble drug camptothecin. J Biomed Nanotechnol 1:190-195.
    • (2005) J Biomed Nanotechnol , vol.1 , pp. 190-195
    • Li, M.1    Chrastina, A.2    Levchenko, T.3    Torchilin, V.P.4
  • 57
    • 0022398674 scopus 로고
    • The influence of three poly(oxyethy-lene)poly(oxypropylene) surface-active block copolymers on the solubility behavior of indomethacin
    • Lin SY, Kawashima Y. 1985. The influence of three poly(oxyethy-lene) poly(oxypropylene) surface-active block copolymers on the solubility behavior of indomethacin. Pharm Acta Helv 60: 339-344.
    • (1985) Pharm Acta Helv , vol.60 , pp. 339-344
    • Lin, S.Y.1    Kawashima, Y.2
  • 58
    • 0023624171 scopus 로고
    • Pluronic surfactants affecting diaz-epam solubility, compatibility, and adsorption from i.v. admixture solutions
    • Lin SY, Kawashima Y. 1987. Pluronic surfactants affecting diaz-epam solubility, compatibility, and adsorption from i.v. admixture solutions. J Parenter Sci Technol 41:83-87.
    • (1987) J Parenter Sci Technol , vol.41 , pp. 83-87
    • Lin, S.Y.1    Kawashima, Y.2
  • 59
    • 0037394663 scopus 로고    scopus 로고
    • Stability and release performance of a series of pegylated copolymeric micelles
    • Lin WJ, Juang LW, Lin CC. 2003. Stability and release performance of a series of pegylated copolymeric micelles. Pharm Res 20:668-673.
    • (2003) Pharm Res , vol.20 , pp. 668-673
    • Lin, W.J.1    Juang, L.W.2    Lin, C.C.3
  • 60
    • 33751509349 scopus 로고    scopus 로고
    • Formulation of drugs in block copolymer micelles: Drug loading and release
    • Liu J, Lee H, Allen C. 2006. Formulation of drugs in block copolymer micelles: Drug loading and release. Curr Pharm Des 12:4685-4701.
    • (2006) Curr Pharm des , vol.12 , pp. 4685-4701
    • Liu, J.1    Lee, H.2    Allen, C.3
  • 61
    • 0036803285 scopus 로고    scopus 로고
    • Polyethylene glycol-diacyllipid micelles demonstrate increased accumulation in subcutaneous tumors in mice
    • Lukyanov AN, Gao Z, Mazzola L, Torchilin VP. 2002. Polyethylene glycol-diacyllipid micelles demonstrate increased accumulation in subcutaneous tumors in mice. Pharm Res 19: 1424-1429.
    • (2002) Pharm Res , vol.19 , pp. 1424-1429
    • Lukyanov, A.N.1    Gao, Z.2    Mazzola, L.3    Torchilin, V.P.4
  • 62
    • 0347996095 scopus 로고    scopus 로고
    • Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits
    • Lukyanov AN, Hartner WC, Torchilin VP. 2004. Increased accumulation of PEG-PE micelles in the area of experimental myocardial infarction in rabbits. J Control Release 94:187-193.
    • (2004) J Control Release , vol.94 , pp. 187-193
    • Lukyanov, A.N.1    Hartner, W.C.2    Torchilin, V.P.3
  • 63
    • 1942486331 scopus 로고    scopus 로고
    • Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs
    • Lukyanov AN, Torchilin VP. 2004. Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. Adv Drug Deliv Rev 56:1273-1289.
    • (2004) Adv Drug Deliv Rev , vol.56 , pp. 1273-1289
    • Lukyanov, A.N.1    Torchilin, V.P.2
  • 64
    • 0035291191 scopus 로고    scopus 로고
    • SMANCS and polymer-conjugated macromolec-ular drugs: Advantages in cancer chemotherapy
    • Maeda H. 2001. SMANCS and polymer-conjugated macromolec-ular drugs: Advantages in cancer chemotherapy. Adv Drug Deliv Rev 46:169-185.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 169-185
    • Maeda, H.1
  • 65
    • 0035816204 scopus 로고    scopus 로고
    • Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS
    • Maeda H, Sawa T, Konno T. 2001. Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS. J Control Release 74:47-61.
    • (2001) J Control Release , vol.74 , pp. 47-61
    • Maeda, H.1    Sawa, T.2    Konno, T.3
  • 66
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. 2000. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review. J Control Release 65:271-284.
    • (2000) J Control Release , vol.65 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 67
    • 0004135189 scopus 로고
    • Martin A editor Philadelphia, USA Lippincott Williams and Wilkins
    • Martin A, editor. 1993. Physical pharmacy. Philadelphia, USA: Lippincott, Williams and Wilkins.
    • (1993) Physical Pharmacy
  • 68
    • 33344463203 scopus 로고    scopus 로고
    • Intestinal uptake and biodistribution of novel polymeric micelles after oral administration
    • Mathot F, Van Beijsterveldt L, Preat V, Brewster M, Arien A. 2006. Intestinal uptake and biodistribution of novel polymeric micelles after oral administration. J Control Release 111:47-55.
    • (2006) J Control Release , vol.111 , pp. 47-55
    • Mathot, F.1    Van Beijsterveldt, L.2    Preat, V.3    Brewster, M.4    Arien, A.5
  • 69
    • 0033042635 scopus 로고    scopus 로고
    • Reduction of the side effects of an antitumor agent, KRN5500, by incorporation of the drug into polymeric micelles
    • Matsumura Y, Yokoyama M, Kataoka K, Okano T, Sakurai Y, Kawaguchi T, Kakizoe T. 1999. Reduction of the side effects of an antitumor agent, KRN5500, by incorporation of the drug into polymeric micelles. Jpn J Cancer Res 90:122-128.
    • (1999) Jpn J Cancer Res , vol.90 , pp. 122-128
    • Matsumura, Y.1    Yokoyama, M.2    Kataoka, K.3    Okano, T.4    Sakurai, Y.5    Kawaguchi, T.6    Kakizoe, T.7
  • 70
    • 68549126855 scopus 로고    scopus 로고
    • Block copolymer micelles for delivery of cancer therapy: Transport at the whole body, tissue and cellular levels
    • Mikhail AS, Allen C. 2009. Block copolymer micelles for delivery of cancer therapy: Transport at the whole body, tissue and cellular levels. J Control Release 138:214-223.
    • (2009) J Control Release , vol.138 , pp. 214-223
    • Mikhail, A.S.1    Allen, C.2
  • 76
    • 0035816193 scopus 로고    scopus 로고
    • Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiam-mineplatinum(II) in the core
    • Nishiyama N, Kataoka K. 2001. Preparation and characterization of size-controlled polymeric micelle containing cis-dichlorodiam-mineplatinum(II) in the core. J Control Release 74:83-94.
    • (2001) J Control Release , vol.74 , pp. 83-94
    • Nishiyama, N.1    Kataoka, K.2
  • 77
    • 0026100509 scopus 로고
    • Menadione: Spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines
    • Nutter LM, Cheng AL, Hung HL, Hsieh RK, Ngo EO, Liu TW. 1991. Menadione: Spectrum of anticancer activity and effects on nucleotide metabolism in human neoplastic cell lines. Biochem Pharmacol 41:1283-1292.
    • (1991) Biochem Pharmacol , vol.41 , pp. 1283-1292
    • Nutter, L.M.1    Cheng, A.L.2    Hung, H.L.3    Hsieh, R.K.4    Ngo, E.O.5    Liu, T.W.6
  • 78
    • 28444473061 scopus 로고    scopus 로고
    • Folate-conjugated methoxy poly(ethylene glycol)/poly(epsilon- caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery
    • Park EK, Kim SY, Lee SB, Lee YM. 2005. Folate-conjugated methoxy poly(ethylene glycol)/poly(epsilon-caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery. J Control Release 109:158-168.
    • (2005) J Control Release , vol.109 , pp. 158-168
    • Park, E.K.1    Kim, S.Y.2    Lee, S.B.3    Lee, Y.M.4
  • 79
    • 0030973901 scopus 로고    scopus 로고
    • Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: The lack of beneficial effects by coating lipo-somes with poly(ethylene glycol)
    • Parr MJ, Masin D, Cullis PR, Bally MB. 1997. Accumulation of liposomal lipid and encapsulated doxorubicin in murine Lewis lung carcinoma: The lack of beneficial effects by coating lipo-somes with poly(ethylene glycol). J Pharmacol Exp Ther 280:1319-1327.
    • (1997) J Pharmacol Exp Ther , vol.280 , pp. 1319-1327
    • Parr, M.J.1    Masin, D.2    Cullis, P.R.3    Bally, M.B.4
  • 81
    • 33644839318 scopus 로고    scopus 로고
    • Poly(lactide)-poly(ethylene glycol) micelles as a carrier for griseofulvin
    • Pierri E, Avgoustakis K. 2005. Poly(lactide)-poly(ethylene glycol) micelles as a carrier for griseofulvin. J Biomed Mater Res A 75:639-647.
    • (2005) J Biomed Mater Res A , vol.75 , pp. 639-647
    • Pierri, E.1    Avgoustakis, K.2
  • 82
    • 0029987783 scopus 로고    scopus 로고
    • Structure-function relationship among Quillaja saponins serving as exci-pients for nasal and ocular delivery of insulin
    • Pillion DJ, Amsden JA, Kensil CR, Recchia J. 1996. Structure-function relationship among Quillaja saponins serving as exci-pients for nasal and ocular delivery of insulin. J Pharm Sci 85:518-524.
    • (1996) J Pharm Sci , vol.85 , pp. 518-524
    • Pillion, D.J.1    Amsden, J.A.2    Kensil, C.R.3    Recchia, J.4
  • 83
    • 19344369608 scopus 로고    scopus 로고
    • Synthesis of a novel PEG-block-poly(aspartic acid-stat-phenyl-alanine) copolymer shows potential for formation of a micellar drug carrier
    • Prompruk K, Govender T, Zhang S, Xiong CD, Stolnik S. 2005. Synthesis of a novel PEG-block-poly(aspartic acid-stat-phenyl-alanine) copolymer shows potential for formation of a micellar drug carrier. Int J Pharm 297:242-253.
    • (2005) Int J Pharm , vol.297 , pp. 242-253
    • Prompruk, K.1    Govender, T.2    Zhang, S.3    Xiong, C.D.4    Stolnik, S.5
  • 84
    • 50849094554 scopus 로고    scopus 로고
    • TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs
    • Rao KS, Reddy MK, Horning JL, Labhasetwar V. 2008. TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs. Biomaterials 29:4429-4438.
    • (2008) Biomaterials , vol.29 , pp. 4429-4438
    • Rao, K.S.1    Reddy, M.K.2    Horning, J.L.3    Labhasetwar, V.4
  • 85
    • 33644818008 scopus 로고    scopus 로고
    • Solubilization of poorly soluble PDT agent, meso-tetraphenylporphin, in plain or immunotargeted PEG-PE micelles results in dramatically improved cancer cell killing in vitro
    • Roby A, Erdogan S, Torchilin VP. 2006. Solubilization of poorly soluble PDT agent, meso-tetraphenylporphin, in plain or immunotargeted PEG-PE micelles results in dramatically improved cancer cell killing in vitro. Eur J Pharm Biopharm 62:235-240.
    • (2006) Eur J Pharm Biopharm , vol.62 , pp. 235-240
    • Roby, A.1    Erdogan, S.2    Torchilin, V.P.3
  • 86
    • 33646370738 scopus 로고    scopus 로고
    • Assessment of the integrity of poly(caprolactone)-b-poly(ethylene oxide) micelles under biological conditions: A fluorogenic-based approach
    • Savic R, Azzam T, Eisenberg A, Maysinger D. 2006. Assessment of the integrity of poly(caprolactone)-b-poly(ethylene oxide) micelles under biological conditions: A fluorogenic-based approach. Langmuir 22:3570-3578.
    • (2006) Langmuir , vol.22 , pp. 3570-3578
    • Savic, R.1    Azzam, T.2    Eisenberg, A.3    Maysinger, D.4
  • 88
    • 49149088943 scopus 로고    scopus 로고
    • The architecture of ligand attachment to nanocarriers controls their specific interaction with target cells
    • Sawant RR, Sawant RM, Kale AA, Torchilin VP. 2008a. The architecture of ligand attachment to nanocarriers controls their specific interaction with target cells. J Drug Target 16:596-600.
    • (2008) J Drug Target , vol.16 , pp. 596-600
    • Sawant, R.R.1    Sawant, R.M.2    Kale, A.A.3    Torchilin, V.P.4
  • 89
    • 50149092136 scopus 로고    scopus 로고
    • Mixed PEG-PE/ vitamin e tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: Improved drug solubilization and enhanced in vitro cytotoxicity
    • Sawant RR, Sawant RM, Torchilin VP. 2008b. Mixed PEG-PE/ vitamin E tumor-targeted immunomicelles as carriers for poorly soluble anti-cancer drugs: Improved drug solubilization and enhanced in vitro cytotoxicity. Eur J Pharm Biopharm 70: 51-57.
    • (2008) Eur J Pharm Biopharm , vol.70 , pp. 51-57
    • Sawant, R.R.1    Sawant, R.M.2    Torchilin, V.P.3
  • 90
    • 67349169756 scopus 로고    scopus 로고
    • Enhanced cytotoxicity of TATp-bearing paclitaxel-loaded micelles in vitro and in vivo
    • Sawant RR, Torchilin VP. 2009. Enhanced cytotoxicity of TATp-bearing paclitaxel-loaded micelles in vitro and in vivo. Int J Pharm 374:114-118.
    • (2009) Int J Pharm , vol.374 , pp. 114-118
    • Sawant, R.R.1    Torchilin, V.P.2
  • 91
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: Delivery of a biologically active protein into the mouse
    • Schwarze SR, Ho A, Vocero-Akbani A, Dowdy SF. 1999. In vivo protein transduction: Delivery of a biologically active protein into the mouse. Science 285:1569-1572.
    • (1999) Science , vol.285 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 92
    • 33847671358 scopus 로고    scopus 로고
    • TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors
    • Sethuraman VA, Bae YH. 2007. TAT peptide-based micelle system for potential active targeting of anti-cancer agents to acidic solid tumors. J Control Release 118:216-224.
    • (2007) J Control Release , vol.118 , pp. 216-224
    • Sethuraman, V.A.1    Bae, Y.H.2
  • 93
    • 0032559172 scopus 로고    scopus 로고
    • Methoxy poly (ethylene glycol)/epsilon-caprolactone amphiphilic block copol-ymeric micelle containing indomethacin. I. Preparation and characterization
    • Shin IG, Kim SY, Lee YM, Cho CS, Sung YK. 1998. Methoxy poly (ethylene glycol)/epsilon-caprolactone amphiphilic block copol-ymeric micelle containing indomethacin. I. Preparation and characterization. J Control Release 51:1-11.
    • (1998) J Control Release , vol.51 , pp. 1-11
    • Shin, I.G.1    Kim, S.Y.2    Lee, Y.M.3    Cho, C.S.4    Sung, Y.K.5
  • 94
  • 95
    • 47649099709 scopus 로고    scopus 로고
    • Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20-tetraphenylporphin-loaded PEG-PE micelles
    • Skidan I, Dholakia P, Torchilin V. 2008. Photodynamic therapy of experimental B-16 melanoma in mice with tumor-targeted 5,10,15,20- tetraphenylporphin-loaded PEG-PE micelles. J Drug Target 16:486-493.
    • (2008) J Drug Target , vol.16 , pp. 486-493
    • Skidan, I.1    Dholakia, P.2    Torchilin, V.3
  • 96
    • 0026545279 scopus 로고
    • Micelles of poly(oxyethylene)-poly(oxypro-pylene) block copolymer (pluronic) as a tool for low-molecular compound delivery into a cell: Phosphorylation of intracellular proteins with micelle incorporated [gamma-32P]ATP
    • Slepnev VI, Kuznetsova LE, Gubin AN, Batrakova EV, Alakhov V, Kabanov AV. 1992. Micelles of poly(oxyethylene)-poly(oxypro-pylene) block copolymer (pluronic) as a tool for low-molecular compound delivery into a cell: Phosphorylation of intracellular proteins with micelle incorporated [gamma-32P]ATP. Biochem Int 26:587-595.
    • (1992) Biochem Int , vol.26 , pp. 587-595
    • Slepnev, V.I.1    Kuznetsova, L.E.2    Gubin, A.N.3    Batrakova, E.V.4    Alakhov, V.5    Kabanov, A.V.6
  • 98
    • 77950826451 scopus 로고    scopus 로고
    • Shell-sheddable micelles based on dextran-SS-poly(epsilon-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin
    • Sun H, Guo B, Li X, Cheng R, Meng F, Liu H, Zhong Z. 2010. Shell-sheddable micelles based on dextran-SS-poly(epsilon-caprolactone) diblock copolymer for efficient intracellular release of doxorubicin. Biomacromolecules 11:848-854.
    • (2010) Biomacromolecules , vol.11 , pp. 848-854
    • Sun, H.1    Guo, B.2    Li, X.3    Cheng, R.4    Meng, F.5    Liu, H.6    Zhong, Z.7
  • 99
    • 60749121731 scopus 로고    scopus 로고
    • Multifunctional and stimuli-sensitive pharmaceutical nanocarriers
    • Torchilin V. 2009. Multifunctional and stimuli-sensitive pharmaceutical nanocarriers. Eur J Pharm Biopharm 71: 431-444.
    • (2009) Eur J Pharm Biopharm , vol.71 , pp. 431-444
    • Torchilin, V.1
  • 100
    • 0035850224 scopus 로고    scopus 로고
    • Structure and design of polymeric surfactant-based drug delivery systems
    • Torchilin VP. 2001. Structure and design of polymeric surfactant-based drug delivery systems. J Control Release 73:137-172.
    • (2001) J Control Release , vol.73 , pp. 137-172
    • Torchilin, V.P.1
  • 101
    • 7044270898 scopus 로고    scopus 로고
    • Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate
    • Torchilin VP. 2005a. Fluorescence microscopy to follow the targeting of liposomes and micelles to cells and their intracellular fate. Adv Drug Deliv Rev 57:95-109.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 95-109
    • Torchilin, V.P.1
  • 102
    • 14144250911 scopus 로고    scopus 로고
    • Recent advances with liposomes as pharmaceutical carriers
    • Torchilin VP. 2005b. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 4:145-160.
    • (2005) Nat Rev Drug Discov , vol.4 , pp. 145-160
    • Torchilin, V.P.1
  • 103
    • 33845388144 scopus 로고    scopus 로고
    • Micellar nanocarriers: Pharmaceutical perspectives
    • Torchilin VP. 2007. Micellar nanocarriers: Pharmaceutical perspectives. Pharm Res 24:1-16.
    • (2007) Pharm Res , vol.24 , pp. 1-16
    • Torchilin, V.P.1
  • 104
    • 0035795123 scopus 로고    scopus 로고
    • P-Nitrophenylcarbonyl-PEG-PE-liposomes: Fast and simple attachment of specific ligands, including monoclonal antibodies, to distal ends of PEG chains via p-nitrophenylcarbo-nyl groups
    • Torchilin VP, Levchenko TS, Lukyanov AN, Khaw BA, Klibanov AL, Rammohan R, Samokhin GP, Whiteman KR. 2001a. p-Nitrophenylcarbonyl-PEG-PE-liposomes: Fast and simple attachment of specific ligands, including monoclonal antibodies, to distal ends of PEG chains via p-nitrophenylcarbo-nyl groups. Biochim Biophys Acta 1511:397-411.
    • (2001) Biochim Biophys Acta , vol.1511 , pp. 397-411
    • Torchilin, V.P.1    Levchenko, T.S.2    Lukyanov, A.N.3    Khaw, B.A.4    Klibanov, A.L.5    Rammohan, R.6    Samokhin, G.P.7    Whiteman, K.R.8
  • 106
    • 0035902477 scopus 로고    scopus 로고
    • TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors
    • Torchilin VP, Rammohan R, Weissig V, Levchenko TS. 2001b. TAT peptide on the surface of liposomes affords their efficient intracellular delivery even at low temperature and in the presence of metabolic inhibitors. Proc Natl Acad Sci USA 98: 8786-8791.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8786-8791
    • Torchilin, V.P.1    Rammohan, R.2    Weissig, V.3    Levchenko, T.S.4
  • 108
    • 0035003021 scopus 로고    scopus 로고
    • Role of formulation vehicles in taxane pharmacology
    • Van Zuylen L, Verweij J, Sparreboom A. 2001. Role of formulation vehicles in taxane pharmacology. Invest New Drugs 19: 125-141.
    • (2001) Invest New Drugs , vol.19 , pp. 125-141
    • Van Zuylen, L.1    Verweij, J.2    Sparreboom, A.3
  • 109
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply and metabolic microenvironment of human tumors: A review
    • Vaupel P, Kallinowsky F, Okunieff P. 1989. Blood flow, oxygen and nutrient supply and metabolic microenvironment of human tumors: A review. Cancer Res 49:6449-6465.
    • (1989) Cancer Res , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowsky, F.2    Okunieff, P.3
  • 111
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • Wadia JS, Stan RV, Dowdy SF. 2004. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 10:310-315.
    • (2004) Nat Med , vol.10 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 112
    • 14644405045 scopus 로고    scopus 로고
    • Polymeric micelles for delivery of poorly soluble drugs: Preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids
    • Wang J, Mongayt D, Torchilin VP. 2005. Polymeric micelles for delivery of poorly soluble drugs: Preparation and anticancer activity in vitro of paclitaxel incorporated into mixed micelles based on poly(ethylene glycol)-lipid conjugate and positively charged lipids. J Drug Target 13:73-80.
    • (2005) J Drug Target , vol.13 , pp. 73-80
    • Wang, J.1    Mongayt, D.2    Torchilin, V.P.3
  • 113
    • 1442299816 scopus 로고    scopus 로고
    • Preparation and in vitro synergistic anti-cancer effect of vitamin K3 and 1,8-diazabicyclo[5,4,0]undec-7-ene in poly(ethylene glycol)-diacyllipid micelles
    • Wang J, Mongayt DA, Lukyanov AN, Levchenko TS, Torchilin VP. 2004. Preparation and in vitro synergistic anti-cancer effect of vitamin K3 and 1,8-diazabicyclo[5,4,0]undec-7-ene in poly(ethylene glycol)-diacyllipid micelles. Int J Pharm 272:129-135.
    • (2004) Int J Pharm , vol.272 , pp. 129-135
    • Wang, J.1    Mongayt, D.A.2    Lukyanov, A.N.3    Levchenko, T.S.4    Torchilin, V.P.5
  • 114
    • 30744471427 scopus 로고    scopus 로고
    • Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability
    • Watanabe M, Kawano K, Yokoyama M, Opanasopit P, Okano T, Maitani Y. 2006. Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation and circulation stability. Int J Pharm 308:183-189.
    • (2006) Int J Pharm , vol.308 , pp. 183-189
    • Watanabe, M.1    Kawano, K.2    Yokoyama, M.3    Opanasopit, P.4    Okano, T.5    Maitani, Y.6
  • 116
    • 0031683986 scopus 로고    scopus 로고
    • Micellar delivery system for dequalinium-a lipophilic cationic drug with anticarcinoma activity
    • Weissig V, Lizano C, Torchilin VP. 1998a. Micellar delivery system for dequalinium-a lipophilic cationic drug with anticarcinoma activity. J Liposome Res 8:391-400.
    • (1998) J Liposome Res , vol.8 , pp. 391-400
    • Weissig, V.1    Lizano, C.2    Torchilin, V.P.3
  • 117
    • 0031665983 scopus 로고    scopus 로고
    • Accumulation of protein-loaded long-circulating micelles and liposomes in subcutaneous Lewis lung carcinoma in mice
    • Weissig V, Whiteman KR, Torchilin VP. 1998b. Accumulation of protein-loaded long-circulating micelles and liposomes in subcutaneous Lewis lung carcinoma in mice. Pharm Res 15: 1552-1556.
    • (1998) Pharm Res , vol.15 , pp. 1552-1556
    • Weissig, V.1    Whiteman, K.R.2    Torchilin, V.P.3
  • 118
    • 0032472352 scopus 로고    scopus 로고
    • Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor
    • Yokoyama M, Fukushima S, Uehara R, Okamoto K, Kataoka K, Sakurai Y, Okano T. 1998a. Characterization of physical entrapment and chemical conjugation of adriamycin in polymeric micelles and their design for in vivo delivery to a solid tumor. J Control Release 50:79-92.
    • (1998) J Control Release , vol.50 , pp. 79-92
    • Yokoyama, M.1    Fukushima, S.2    Uehara, R.3    Okamoto, K.4    Kataoka, K.5    Sakurai, Y.6    Okano, T.7
  • 120
    • 0025343062 scopus 로고
    • Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adria-mycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer
    • Yokoyama M, Miyauchi M, Yamada N, Okano T, Sakurai Y, Kataoka K, Inoue S. 1990. Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adria-mycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer. Cancer Res 50:1693-1700.
    • (1990) Cancer Res , vol.50 , pp. 1693-1700
    • Yokoyama, M.1    Miyauchi, M.2    Yamada, N.3    Okano, T.4    Sakurai, Y.5    Kataoka, K.6    Inoue, S.7
  • 121
    • 0031722638 scopus 로고    scopus 로고
    • Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size
    • Yokoyama M, Satoh A, Sakurai Y, Okano T, Matsumura Y, Kakizoe T, Kataoka K. 1998b. Incorporation of water-insoluble anticancer drug into polymeric micelles and control of their particle size. J Control Release 55:219-229.
    • (1998) J Control Release , vol.55 , pp. 219-229
    • Yokoyama, M.1    Satoh, A.2    Sakurai, Y.3    Okano, T.4    Matsumura, Y.5    Kakizoe, T.6    Kataoka, K.7
  • 122
    • 0032580499 scopus 로고    scopus 로고
    • Polymeric micelles for drug delivery: Solubilization and haemolytic activity of amphotericin B
    • Yu BG, Okano T, Kataoka K, Kwon G. 1998. Polymeric micelles for drug delivery: Solubilization and haemolytic activity of amphotericin B. J Control Release 53:131-136.
    • (1998) J Control Release , vol.53 , pp. 131-136
    • Yu, B.G.1    Okano, T.2    Kataoka, K.3    Kwon, G.4
  • 123
    • 33645469800 scopus 로고    scopus 로고
    • Epidermal growth factor-conjugated poly(ethylene glycol)-block- poly(delta-valerolactone) copoly-mer micelles for targeted delivery of chemotherapeutics
    • Zeng F, Lee H, Allen C. 2006. Epidermal growth factor-conjugated poly(ethylene glycol)-block-poly(delta-valerolactone) copoly-mer micelles for targeted delivery of chemotherapeutics. Bio-conjug Chem 17:399-409.
    • (2006) Bio-conjug Chem , vol.17 , pp. 399-409
    • Zeng, F.1    Lee, H.2    Allen, C.3
  • 124
    • 77950515941 scopus 로고    scopus 로고
    • Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect
    • Zhan C, Gu B, Xie C, Li J, Liu Y, Lu W. 2010. Cyclic RGD conjugated poly(ethylene glycol)-co-poly(lactic acid) micelle enhances paclitaxel anti-glioblastoma effect. J Control Release 143:136-142.
    • (2010) J Control Release , vol.143 , pp. 136-142
    • Zhan, C.1    Gu, B.2    Xie, C.3    Li, J.4    Liu, Y.5    Lu, W.6
  • 125
    • 0036074845 scopus 로고    scopus 로고
    • Differential conjugation of tat peptide to superparamagnetic nano-particles and its effect on cellular uptake
    • Zhao M, Kircher MF, Josephson L, Weissleder R. 2002. Differential conjugation of tat peptide to superparamagnetic nano-particles and its effect on cellular uptake. Bioconjug Chem 13:840-844.
    • (2002) Bioconjug Chem , vol.13 , pp. 840-844
    • Zhao, M.1    Kircher, M.F.2    Josephson, L.3    Weissleder, R.4
  • 126
    • 13844254266 scopus 로고    scopus 로고
    • Cell-penetrating peptides: Mechanism and kinetics of cargo delivery
    • Zorko M, Langel U. 2005. Cell-penetrating peptides: Mechanism and kinetics of cargo delivery. Adv Drug Deliv Rev 57: 529-545.
    • (2005) Adv Drug Deliv Rev , vol.57 , pp. 529-545
    • Zorko, M.1    Langel, U.2


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