Effects of discrete kainic acid-induced hippocampal lesions on spatial and contextual learning and memory in rats

Brain Research

Volumn 716, Issue 1-2, 1996, Pages 29-38

  Stubley Weatherly, LeighAnn ^a   Harding, Joseph W ^a   Wright, John W ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

CA1; CA3; hippocampus; kainic acid; memory; passive avoidance; spatial learning; water maze

Indexed keywords

KAINIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; BRAIN INJURY; CONTROLLED STUDY; HIPPOCAMPUS; HISTOLOGY; MALE; MAZE TEST; MEMORY; NONHUMAN; PRIORITY JOURNAL; RAT; SPATIAL MEMORY;

EID: 0029922733     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-8993(95)01589-2     Document Type: Article

References (63)

1. Amaral, D.G., Ishizuka, N. and Claiborne, B., Neuron, numbers and the hippocampal network, Prog. Brain Res., 83 (1990) 1-11.
2. Ben-Ari, Y., Lagowska, J., Tremblay, E. and Le Gal La Salle, G., A new model of focal status epilepticus: Intra-amygdaloid application of kainic acid elicits repetitive secondarily generated convulsive seizures, Brain Res., 191 (1979) 176-180.
3. Ben-Ari, Y., Tremblay, E. and Ottersen, O.P., Injections of kainic acid into the amygdaloid complex of the rat: An electrographic, clinical and histological study in relation to the pathology of epilepsy, Neuroscience, 5 (1980) 515-528.
4. Ben-Ari, Y., Tremblay, E., Riche, D., Ghilini, G. and Naquet, R., Electrographic, clinical, and pathological alterations following systemic administration of kainic acid, bicuculline and pentetrazole: Metabolic mapping using the deoxyglucose method with special reference to the pathology of epilepsy. Neuroscience, 6 (1981) 1361-1391.
5. Berger, M.L., Charton, G. and Ben-Ari, Y., Effects of seizure-induced by intra-amygdaloid kainic acid on kainic acid binding sites in rat hippocampus and amygdala, J. Neurochem., 47 (1986a) 720-727.
6. Blackstad, T.W., Commissural connections of the hippocampal region in the rat, with special reference to their mode of termination, J. Comp. Neurol., 105 (1956) 417-537.
7. Bliss, T.V.P. and Lomo, T., Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path, J. Physiol., 232 (1973) 331-356.
8. Boss, B.D., Turlejski, K., Stanfield, B.B. and Cowan, W.M., On the numbers of neurons in fields CA1 and CA3 of the hippocampus of Sprague-Dawley and Wistar rats, Brain Res., 406 (1987) 280-287.
9. Caronna, J.J., Diagnosis, prognosis, and treatment of hypoxic coma. In Fahn, J.N. Davis and L.P. Rowland (Eds.), Advances in Neurology, Vol. 26, Raven Press, New York, 1979, pp. 1-19.
10. Cavalheiro, E., Riche, D. and Le Gal La Salle, G., Longterm effects of intra-hippocampal kainic acid in rats: A method for inducing spontaneous recurrent seizures, Electroencephalgr. Clin. Neurophysiol., 53 (1982) 581-582.
11. Chronister, R.B. and White, L.E., Jr., Fiberarchitecture of the hippocampal formation: Anatomy, projections, and structural significance. In R.L. Isaacson and K.H. Pribram (Eds.), The Hippocampus, Vol. I: Structure and Development, Plenum Press, New York, 1975, pp. 9-39.
12. Cohen, N.J. and Eichenbaum, H., The theory that wouldn't die: A critical look at the spatial mapping theory of hippocampal function, Hippocampus, 1 (1991) 265-268.
13. Cummings, J.L., Tomiyasu, U., Read, S. and Benson, D.F., Amnesia with hippocampal lesions after cardiopulmonary arrest, Neurology, 34 (1984) 679-681.
14. Davidson, T.L., McKernan, M.G. and Jarrard, L.E., Hippocampal lesions do not impair negative patterning: A challenge to configural association theory, Behav. Neurosci., 107 (1993) 227-234.
15. Davis, S., Butcher, S.P. and Morris, R.G.M., The NMDA receptor antagonist D-2-amino-5-phophonopentanoate (D-AP5) impairs spatial learning and LTP in vivo at intracerebral concentrations comparable to those that block LTP in vitro, J. Neurosci., 12 (1992) 21-34.
16. French, E.D., Alsinio, C. and Schwarcz, R., Intrahippocampal kainic acid, seizures and local neuronal degeneration: Relationships assessed in unanesthetized rats, Neuroscience, 7 (1982) 2525-2536.
17. Hyman, B.T., vanHoesen, G.W., Damasio, A.R. and Barnes, C.L., Alzheimer's disease: Cell-specific pathology isolates the hippocampal formation, Science, 225 (1982) 1168-1170.
18. Jarrard, L.E., The hippocampus and motivation, Psychol. Bull., 79 (1973) 1-12.
19. Jarrard, L.E., Selective hippocampal lesions and behavior: Effects of kainic acid lesions on performance of place and cue tasks, Behav. Neurosci., 97 (1983) 873-889.
20. Jarrard, L.E., Selective hippocampal lesions and behavior: Implications for current research and theorizing. In R.L. Issacson and K.H. Pribram (Eds.), The Hippocampus: Vol. 4, Plenum Press, New York, 1986, pp. 93-126.
21. Jarrard, L.E., On the use of ibotenic acid to lesion selectively different components of the hippocampal formation, J. Neurosci. Methods, 29 (1989) 251-259.
22. Jarrard, L.E., Use of ibotenic acid to selectively lesion brain structures. In P.M. Conn (Ed.), Methods in Neurosciences: Vol. 7, Academic Press, San Diego, 1991, pp. 58-69.
23. Jarrard, L.E., On the role of the hippocampus in learning and memory in the rat, Behav. Neural Biol., 60 (1993) 9-26.
24. Jarrard, L.E. and Davidson, T.L., Acquisition of concurrent conditional discriminations in rats with ibotenate lesions of hippocampus and of subiculum, Psychobiology, 18 (1990) 68-73.
25. Leach, L., Whishaw, I.Q. and Kolb, B., Effects of kainic acid lesions in the lateral hypothalamus on behavior and hippocampal and neocortical electroencephalographic (EEG) activity in the rat, Behav. Brain Res., 1 (1980) 411-431.
26. Lorente de No', R., Studies on the structure of the cerebral cortex. II. Continuation of the study of the ammonic system, J. fur Psychol. und Neurol., 46 (1934) 113-177.
27. Lothman, E.W. and Collins, R.C., Kainic acid-induced limbic motor seizures: Metabolic, behavioral, electroencephalographic and neuropathological correlates, Brain Res., 218 (1981) 299-318.
28. Lynch, G., Karson, J., Kelso, S., Barrionuevo, G. and Schottler, F., Intracellular injection of EGTA blocks induction of hippocampal long-term potentiation. Nature, 305 (1983) 719-721.
29. Malenka, R.C., Kauer, J.A., Zucker, R.S. and Nicoll, R.A., Post-synaptic calcium is sufficient for potentiation of hippocampal synaptic transmission, Science, 242 (1988) 81-84.
30. McNaughton, B.L., Barnes, C.A., Meltzer, J. and Sutherland, R.J., Hippocampal granule cells are necessary for normal spatial learning but not for spatially-selective pyramidal cell discharge, Exp. Brain Res., 76 (1989) 485-496.
31. Morris, R.G.M., Spatial location does not require the presence of local cues, Learn. Motiv., 12 (1981) 239-260.
32. Morris, R.G.M., Anderson, E., Lynch, G.S. and Baudry, M., Selective impairment of learning and blockade of long-term potentiation by N-methyl-D-aspartate antagonist, AP-5, Nature, 319 (1986) 774-776.
33. Morris, R.G.M., Garrud, P., Rawlins, J.N.P. and O'Keefe, J., Place navigation impaired in rats with hippocampal lesions, Nature, 297 (1982) 681-683.
34. Morris, R.G.M., Schenk, F., Tweedie, F. and Jarrard, L.E., Ibotenate lesions of hippocampus and/or subiculum: Dissociating components of allocentric spatial learning, Eur: J. Neurosci., 2 (1990) 1016-1028.
35. Nadel, L., The hippocampus and space revisited, Hippocampus, I (1991) 221-229.
36. Nelson, M.F., Zaczek, R. and Coyle, J.T., Effects of sustained seizures produced by intrahippocampal injection of kainic acid on noradrenergic neurons: Evidence for focal control of norepinephrine release, J. Pharmacol. Exp. Ther., 214(3) (1980) 694-702.
37. O'Keefe, J., Place units in the hippocampus of the freely moving rat, Exp. Neurol., 51 (1976) 78-109.
38. O'Keefe, J. and Dostrovsky, J., The hippocampus as a spatial map: Preliminary evidence from unit activity in the freely-moving rat, Brain Res., 34 (1971) 171-175.
39. O'Keefe, J. and Nadel, L., The Hippocampus as a Cognitive Map, Oxford University Press, Oxford, 1978.
40. Olton, D.S., Becker, J.T. and Handelmann, G.E., Hippocampus, space and memory, Behav. Brain Sci., 2 (1979) 313-365.
41. Papez, J.W., A proposed mechanism of emotion, Arch. Neurol. Psychiatry, 38 (1937) 725-743.
42. Pulsinelli, W.A., Brierley, J.B. and Plum, F., Temporal profile of neuronal damage in a model of transient forebrain ischemia, Ann. Neurol., 11(5) (1982) 491-498.
43. Ramon y Cajal, S., Estructura del asta de Ammon, Anales de la Soc. Esp. de Hist. Natural, 22 (1893) 53-114.
44. Schmidt-Kastner, R. and Freund, T.F., Selective vulnerability of the hippocampus in brain ischemia, Neuroscience, 40(3) (1991) 599-636.
45. Schwob, J.E., Fuller, T., Price, J.L. and Olney, J.W., Widespread patterns of neuronal damage following systemic or intracerebral injection of kainic acid: A histological study, Neuroscience, 5 (1980) 991-1014.
46. Scoville, W.B. and Milner, B., Loss of recent memory after bilateral hippocampal lesions, J. Neurol. Neurosurg. Psychiatry, 20 (1957) 11-21.
47. Sloviter, R.S. and Damiano, B.P., On the relationship between kainic acid-induced epileptiform activity and hippocampal neuronal damage, Neuropharmacology, 20 (1981) 1003-1011.
48. Sperk, G., Kainic acid seizures in the rat, Prog. Neurobiol., 42 (1994) 1-32.
49. Sperk, G., Lassmann, H., Baran, H., Seitelberger, F. and Hornykiewicz, O., Kainic acid-induced seizures: Dose-relationship of behavioural, neurochemical and histopathological changes, Brain Res., 338 (1985) 289-295.
50. Squire, L.R., Memory and Brain, Oxford University Press, New York, 1987.
51. Stubley, L., Mungall, B.A. and Wright, J.W., The disruption of spatial and associative memories after kainic acid-induced selective hippocampal lesions in rats, Soc. Neurosci. Abstr., 20 (1994) 807.
52. Sutherland, R.J., Kolb, B. and Whishaw, I.Q., Spatial mapping: definitive disruption by hippocampal or medial frontal cortical damage in the rat, Neurosci. Lett., 31 (1982) 271-276.
53. Sutherland, R.J., McDonald, R.J., Hill, C.R. and Rudy, J.W., Damage to the hippocampal formation in rats selectively impairs the ability to learn cue relationships, Behav. Neural Biol., 52 (1989) 331-356.
54. Sutherland, R.J., Whishaw, I.Q. and Kolb, B., A behavioral analysis of spatial localization following electrolytic, kainate- or colchicine-induced damage to the hippocampal formation in the rat, Behav. Brain Res., 7 (1983) 133-153.
55. Thinus-Blanc, C., Save, E., Poucet, B. and Buhot, M.C., The effects of reversible inactivations of the hippocampus on exploratory activity and spatial memory, Hippocampus, 1 (1991) 365-372.
56. Volpe, B.T., Davis, H.P., Towle, A. and Dunlop, W.P., Loss of hippocampal CA1 pyramidal neurons correlates with memory impairment in rats with ischemic or neurotoxin lesions, Behav. Neurosci., 106 (1992) 457-464.
57. Volpe, B.T. and Hirst, W., The characterization of an amnesic syndrome following hypoxic ischemic injury, Arch. Neurol., 40 (1983) 436-440.
58. 3-4 lesions impair formation of a place learning-set in the rat and induce reflex epilepsy, Behav. Brain Res., 24 (1987) 59-72.
59. Whishaw, I.Q. and Sutherland, R.J., Sparing of rhythmical slow activity (RSA or theta) in two hippocampal generators after kainic acid CA3 and CA4 lesions, Exp. Neurol., 75 (1982) 711-728.
60. Wilson, M.A. and McNaughton, B.L., Dynamics of the hippocampal ensemble code for space, Science, 261 (1993) 1055-1058.
61. Wood, E.R., Mumby, D.G., Pinel, J.P.J. and Phillips, A.G., Impaired object recognition memory in rats following ischemia-induced damage to the hippocampus, Behav. Neurosci., 107 (1993) 51-62.
62. Zola-Morgan, S., Squire, L.R. and Amaral, D.G., Human amnesia and the medial-temporal region: Enduring memory impairment following a bilateral lesion limited to field CA1 of the hippocampus, J. Neurosci., 6 (1986) 2950-2967.
63. Zucker, D.K., Wooten, G.F., Lothman, E.M. and Olney, J.W., Neuropathological changes associated with intravenous kainic acid, J. Neuropathol. Exp. Neurol. 40 (1981) 324.