Neuroprotection by scatter factor/hepatocyte growth factor and FGF-1 in cerebellar granule neurons is phosphatidylinositol 3-kinase/Akt-dependent and MAPK/CREB-independent

Journal of Neurochemistry

Volumn 81, Issue 2, 2002, Pages 365-378

  Hossain, Mir Ahamed ^a,b   Russell, Juliet C ^b   Gomes, Raquel ^b   Laterra, John ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

Akt; Cerebellar granule neurons; Excitotoxicity; Mitogen activated protein kinase; Neuroprotection; Neurotrophic factors

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BRAIN DERIVED NEUROTROPHIC FACTOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FIBROBLAST GROWTH FACTOR 1; MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; QUINOLINIC ACID; SCATTER FACTOR; WORTMANNIN;

ANIMAL CELL; ARTICLE; CELL VIABILITY; CEREBELLUM; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; GENETIC TRANSFECTION; GRANULE CELL; IMMUNOBLOTTING; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYTOPROTECTION; ENZYME ACTIVATION; ENZYME INHIBITORS; EXCITATORY AMINO ACID AGONISTS; FIBROBLAST GROWTH FACTOR 1; HEPATOCYTE GROWTH FACTOR; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MET; RATS; RATS, INBRED LEW;

ANIMALIA; TRIXIS;

EID: 0036316595     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2002.00837.x     Document Type: Article

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