메뉴 건너뛰기




Volumn 31, Issue 1, 2008, Pages 58-73

Brain angiotensin enhances dopaminergic cell death via microglial activation and NADPH-derived ROS

Author keywords

Angiotensin; Dopamine; Microglia; NADPH oxidase; Neuroinflammation; Parkinson

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN II; DIPEPTIDYL CARBOXYPEPTIDASE; MESSENGER RNA; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 45249101114     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2008.03.003     Document Type: Article
Times cited : (175)

References (68)
  • 2
    • 0031571317 scopus 로고    scopus 로고
    • IL-12 production by central nervous system microglia is inhibited by astrocytes
    • Aloisi F., Penna G., Cerase J., Menéndez Iglesias B., and Adorini L. IL-12 production by central nervous system microglia is inhibited by astrocytes. J. Immunol. 159 (1997) 1604-1612
    • (1997) J. Immunol. , vol.159 , pp. 1604-1612
    • Aloisi, F.1    Penna, G.2    Cerase, J.3    Menéndez Iglesias, B.4    Adorini, L.5
  • 3
    • 3142514196 scopus 로고    scopus 로고
    • Oxidative stress in neurodegeneration: cause or consequence
    • Andersen J.K. Oxidative stress in neurodegeneration: cause or consequence. Nat. Med. 10 (2004) S18-S25
    • (2004) Nat. Med. , vol.10
    • Andersen, J.K.1
  • 4
    • 0033105874 scopus 로고    scopus 로고
    • NADPH oxidase: an update
    • Babior B. NADPH oxidase: an update. Blood 93 (1999) 1464-1476
    • (1999) Blood , vol.93 , pp. 1464-1476
    • Babior, B.1
  • 6
    • 0014887858 scopus 로고
    • Time course of the effects of 6-hydroxydopamine on catecholamine-containing neurones in rat hypothalamus and striatum
    • Bell L.J., Iversen L.L., and Uretsky N.J. Time course of the effects of 6-hydroxydopamine on catecholamine-containing neurones in rat hypothalamus and striatum. Br. J. Pharmacol. 40 (1970) 790-799
    • (1970) Br. J. Pharmacol. , vol.40 , pp. 790-799
    • Bell, L.J.1    Iversen, L.L.2    Uretsky, N.J.3
  • 7
    • 0030725572 scopus 로고    scopus 로고
    • Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease
    • Björklund A., Rosenblad C., Winkler C., and Kirik D. Studies on neuroprotective and regenerative effects of GDNF in a partial lesion model of Parkinson's disease. Neurobiol. Dis. 4 (1997) 186-200
    • (1997) Neurobiol. Dis. , vol.4 , pp. 186-200
    • Björklund, A.1    Rosenblad, C.2    Winkler, C.3    Kirik, D.4
  • 8
    • 24144453087 scopus 로고    scopus 로고
    • Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism
    • Block M.L., and Hong J.S. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog. Neurobiol. 76 (2005) 77-98
    • (2005) Prog. Neurobiol. , vol.76 , pp. 77-98
    • Block, M.L.1    Hong, J.S.2
  • 9
    • 33644901275 scopus 로고    scopus 로고
    • Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin
    • Block M.L., Li G., Qin L., Wu X., Pei Z., Wang T., Wilson B., Yang J., and Hong J.S. Potent regulation of microglia-derived oxidative stress and dopaminergic neuron survival: substance P vs. dynorphin. FASEB J 20 (2006) 251-258
    • (2006) FASEB J , vol.20 , pp. 251-258
    • Block, M.L.1    Li, G.2    Qin, L.3    Wu, X.4    Pei, Z.5    Wang, T.6    Wilson, B.7    Yang, J.8    Hong, J.S.9
  • 10
    • 0029983547 scopus 로고    scopus 로고
    • Ability of angiotensin II to modulate striatal dopamine release via AT1 receptor in vitro and in vivo
    • Brown D.C., Steward L.J., Ge J., and Barnes N.M. Ability of angiotensin II to modulate striatal dopamine release via AT1 receptor in vitro and in vivo. Br. J. Pharmacol. 18 (1996) 414-420
    • (1996) Br. J. Pharmacol. , vol.18 , pp. 414-420
    • Brown, D.C.1    Steward, L.J.2    Ge, J.3    Barnes, N.M.4
  • 11
    • 18044377401 scopus 로고    scopus 로고
    • NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease
    • Cai H. NAD(P)H oxidase-dependent self-propagation of hydrogen peroxide and vascular disease. Circ. Res. 96 (2005) 818-822
    • (2005) Circ. Res. , vol.96 , pp. 818-822
    • Cai, H.1
  • 13
    • 18144381188 scopus 로고    scopus 로고
    • Dopamine and noradrenaline control distinct functions in rodent microglial cells
    • Färber K., Pannasch U., and Kettenmann H. Dopamine and noradrenaline control distinct functions in rodent microglial cells. Mol. Cell. Neurosci. 29 (2005) 128-138
    • (2005) Mol. Cell. Neurosci. , vol.29 , pp. 128-138
    • Färber, K.1    Pannasch, U.2    Kettenmann, H.3
  • 15
    • 0037443073 scopus 로고    scopus 로고
    • Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease
    • Gao H.M., Hong J.S., Zhang W., and Liu B. Synergistic dopaminergic neurotoxicity of the pesticide rotenone and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease. J. Neurosci. 23 (2003) 1228-1236
    • (2003) J. Neurosci. , vol.23 , pp. 1228-1236
    • Gao, H.M.1    Hong, J.S.2    Zhang, W.3    Liu, B.4
  • 16
    • 84863116750 scopus 로고    scopus 로고
    • Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease
    • Gao H.M., Liu B., Zhang W., and Hong J.S. Critical role of microglial NADPH oxidase-derived free radicals in the in vitro MPTP model of Parkinson's disease. FASEB J 17 (2003) 1954-1956
    • (2003) FASEB J , vol.17 , pp. 1954-1956
    • Gao, H.M.1    Liu, B.2    Zhang, W.3    Hong, J.S.4
  • 17
    • 84863135790 scopus 로고    scopus 로고
    • Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease
    • Gao H.M., Liu B., Zhang W., and Hong J.S. Synergistic dopaminergic neurotoxicity of MPTP and inflammogen lipopolysaccharide: relevance to the etiology of Parkinson's disease. FASEB J 17 (2003) 1957-1959
    • (2003) FASEB J , vol.17 , pp. 1957-1959
    • Gao, H.M.1    Liu, B.2    Zhang, W.3    Hong, J.S.4
  • 18
    • 0347989300 scopus 로고    scopus 로고
    • The angiotensin type 2 receptor of angiotensin II and neuronal differentiation, from observations to mechanisms
    • Gendron L., Payet M.D., and Gallo-Payet N. The angiotensin type 2 receptor of angiotensin II and neuronal differentiation, from observations to mechanisms. J. Mol. Endocrinol. 31 (2003) 359-372
    • (2003) J. Mol. Endocrinol. , vol.31 , pp. 359-372
    • Gendron, L.1    Payet, M.D.2    Gallo-Payet, N.3
  • 19
    • 0036562926 scopus 로고    scopus 로고
    • Effects of orally applied candesartan cilexetil on central responses to angiotensin II in conscious rats
    • Gohlke P., Von Kugelgen S., Jurgensen T., Kox T., Rascher W., Culman J., and Unger T. Effects of orally applied candesartan cilexetil on central responses to angiotensin II in conscious rats. J. Hypertens. 20 (2002) 909-918
    • (2002) J. Hypertens. , vol.20 , pp. 909-918
    • Gohlke, P.1    Von Kugelgen, S.2    Jurgensen, T.3    Kox, T.4    Rascher, W.5    Culman, J.6    Unger, T.7
  • 21
    • 0034677947 scopus 로고    scopus 로고
    • NADPH oxidase. Role in cardiovascular biology and disease
    • Griendling K.K., Sorescu D., and Ushio-Fukai M. NADPH oxidase. Role in cardiovascular biology and disease. Circulation Res. 86 (2000) 494-501
    • (2000) Circulation Res. , vol.86 , pp. 494-501
    • Griendling, K.K.1    Sorescu, D.2    Ushio-Fukai, M.3
  • 22
    • 0023913503 scopus 로고
    • Some new, simple and efficient stereological methods and their use in pathological research and diagnosis
    • Gundersen H.J.G., Bendsen T.F., Korbo L., Marcussen N., Moller A., and Nielsen K. Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APIMS 96 (1988) 379-394
    • (1988) APIMS , vol.96 , pp. 379-394
    • Gundersen, H.J.G.1    Bendsen, T.F.2    Korbo, L.3    Marcussen, N.4    Moller, A.5    Nielsen, K.6
  • 23
    • 35548986304 scopus 로고    scopus 로고
    • Microglia: active sensor and versatile effector cells in the normal and pathologic brain
    • Hanisch U.K., and Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat. Neurosci. 10 (2007) 1387-1394
    • (2007) Nat. Neurosci. , vol.10 , pp. 1387-1394
    • Hanisch, U.K.1    Kettenmann, H.2
  • 24
    • 33646849308 scopus 로고    scopus 로고
    • 6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta
    • Hanrott K., Gudmunsen L., O'Neill M.J., and Wonnacott S. 6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta. J. Biol. Chem. 281 (2006) 5373-5382
    • (2006) J. Biol. Chem. , vol.281 , pp. 5373-5382
    • Hanrott, K.1    Gudmunsen, L.2    O'Neill, M.J.3    Wonnacott, S.4
  • 25
    • 0025217841 scopus 로고
    • Angiotensinogen production by rat astroglial cells in vitro and in vivo
    • Intebi A.D., Flaxman M.S., Ganong W.F., and Deschepper C.F. Angiotensinogen production by rat astroglial cells in vitro and in vivo. Neuroscience 34 (1990) 545-554
    • (1990) Neuroscience , vol.34 , pp. 545-554
    • Intebi, A.D.1    Flaxman, M.S.2    Ganong, W.F.3    Deschepper, C.F.4
  • 26
    • 0031027898 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme modulates dopamine turnover in the striatum
    • Jenkins T.A., Mendelsohn F.A.O., and Chai S.Y. Angiotensin-converting enzyme modulates dopamine turnover in the striatum. J. Neurochem. 68 (1997) 1304-1311
    • (1997) J. Neurochem. , vol.68 , pp. 1304-1311
    • Jenkins, T.A.1    Mendelsohn, F.A.O.2    Chai, S.Y.3
  • 28
    • 0028170674 scopus 로고
    • Increased angiotensin-converting enzyme activity in cerebrospinal fluid of treated patients with Parkinson's disease
    • Konings C.H., Kuiper M.A., Bergmans P.L., Grijpma A.M., van Kamp G.J., and Wolters E.C. Increased angiotensin-converting enzyme activity in cerebrospinal fluid of treated patients with Parkinson's disease. Clin. Chim. Acta 23 (1994) 101-106
    • (1994) Clin. Chim. Acta , vol.23 , pp. 101-106
    • Konings, C.H.1    Kuiper, M.A.2    Bergmans, P.L.3    Grijpma, A.M.4    van Kamp, G.J.5    Wolters, E.C.6
  • 29
    • 0032504657 scopus 로고    scopus 로고
    • Role of mitochondria in oxidative stress and ageing
    • Lenaz G. Role of mitochondria in oxidative stress and ageing. Biochim. Biophys. Acta 1366 (1998) 53-67
    • (1998) Biochim. Biophys. Acta , vol.1366 , pp. 53-67
    • Lenaz, G.1
  • 32
    • 0037099766 scopus 로고    scopus 로고
    • Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson disease
    • Lin J.-J., Yueh K.-C., Chang D.-C., and Lin S.-Z. Association between genetic polymorphism of angiotensin-converting enzyme gene and Parkinson disease. J. Neurol. Sci. 199 (2002) 25-29
    • (2002) J. Neurol. Sci. , vol.199 , pp. 25-29
    • Lin, J.-J.1    Yueh, K.-C.2    Chang, D.-C.3    Lin, S.-Z.4
  • 33
    • 27444435057 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme inhibitors reduce oxidative stress and protect dopaminergic neurons in a 6-hydroxydopamine rat model of parkinsonism
    • Lopez-Real A., Rey P., Soto-Otero R., Mendez-Alvarez E., and Labandeira-Garcia J.L. Angiotensin-converting enzyme inhibitors reduce oxidative stress and protect dopaminergic neurons in a 6-hydroxydopamine rat model of parkinsonism. J. Neurosci. Res. 81 (2005) 865-873
    • (2005) J. Neurosci. Res. , vol.81 , pp. 865-873
    • Lopez-Real, A.1    Rey, P.2    Soto-Otero, R.3    Mendez-Alvarez, E.4    Labandeira-Garcia, J.L.5
  • 34
    • 2342545917 scopus 로고    scopus 로고
    • Sustained blockade of brain AT1 receptors before and after focal cerebral ischemia alleviates neurologic deficits and reduces neuronal injury, apoptosis, and inflammatory responses in the rat
    • Lou M., Blume A., Zhao Y., Gohlke P., Deuschl G., Herdegen T., and Culman J. Sustained blockade of brain AT1 receptors before and after focal cerebral ischemia alleviates neurologic deficits and reduces neuronal injury, apoptosis, and inflammatory responses in the rat. J. Cereb. Blood Flow Metab. 24 (2004) 536-547
    • (2004) J. Cereb. Blood Flow Metab. , vol.24 , pp. 536-547
    • Lou, M.1    Blume, A.2    Zhao, Y.3    Gohlke, P.4    Deuschl, G.5    Herdegen, T.6    Culman, J.7
  • 36
    • 0027156129 scopus 로고
    • Effects of angiotensin II on dopamine and serotonin turnover in the striatum of conscious rat
    • Mendelsohn F.A.O., Jenkins T.A., and Berkovic S.F. Effects of angiotensin II on dopamine and serotonin turnover in the striatum of conscious rat. Brain Res. 613 (1993) 221-229
    • (1993) Brain Res. , vol.613 , pp. 221-229
    • Mendelsohn, F.A.O.1    Jenkins, T.A.2    Berkovic, S.F.3
  • 37
    • 32544455798 scopus 로고    scopus 로고
    • Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation
    • Min K.J., Yang M.S., Kim S.U., Jou I., and Joe E.H. Astrocytes induce hemeoxygenase-1 expression in microglia: a feasible mechanism for preventing excessive brain inflammation. J. Neurosci. 26 (2006) 1880-1887
    • (2006) J. Neurosci. , vol.26 , pp. 1880-1887
    • Min, K.J.1    Yang, M.S.2    Kim, S.U.3    Jou, I.4    Joe, E.H.5
  • 38
    • 33745192816 scopus 로고    scopus 로고
    • Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism
    • Muñoz A., Rey P., Guerra M.J., Mendez-Alvarez E., Soto-Otero R., and Labandeira-Garcia J.L. Reduction of dopaminergic degeneration and oxidative stress by inhibition of angiotensin converting enzyme in a MPTP model of parkinsonism. Neuropharmacology 51 (2006) 112-120
    • (2006) Neuropharmacology , vol.51 , pp. 112-120
    • Muñoz, A.1    Rey, P.2    Guerra, M.J.3    Mendez-Alvarez, E.4    Soto-Otero, R.5    Labandeira-Garcia, J.L.6
  • 39
    • 0035949650 scopus 로고    scopus 로고
    • Are ACE inhibitors a "magic bullet" against oxidative stress?
    • Münzel T., and Keany J.F. Are ACE inhibitors a "magic bullet" against oxidative stress?. Circulation 104 (2001) 1571-1577
    • (2001) Circulation , vol.104 , pp. 1571-1577
    • Münzel, T.1    Keany, J.F.2
  • 41
    • 0034573392 scopus 로고    scopus 로고
    • Induction and activation by Zinc of NADH oxidase in cultured cortical neurons and astrocytes
    • (1-5)
    • Noh K.M., and Koh J. Induction and activation by Zinc of NADH oxidase in cultured cortical neurons and astrocytes. J. Neurosci. 20 (2000) RC111 (1-5)
    • (2000) J. Neurosci. , vol.20
    • Noh, K.M.1    Koh, J.2
  • 42
    • 0035851254 scopus 로고    scopus 로고
    • Ontogeny of angiotensin II type 1 receptor mRNAs in fetal and neonatal rat brain
    • Nuyt A.N., Lenkei Z., Corvol P., Palkovits M., and Llorens-Cortés C. Ontogeny of angiotensin II type 1 receptor mRNAs in fetal and neonatal rat brain. J. Comp. Neurol. 440 (2001) 192-203
    • (2001) J. Comp. Neurol. , vol.440 , pp. 192-203
    • Nuyt, A.N.1    Lenkei, Z.2    Corvol, P.3    Palkovits, M.4    Llorens-Cortés, C.5
  • 44
    • 0031685422 scopus 로고    scopus 로고
    • Experimental developments in movement disorders: uptake on proposed free radical mechanisms
    • Przedborski S., and Jackson-Lewis V. Experimental developments in movement disorders: uptake on proposed free radical mechanisms. Curr. Opin. Neurol. 11 (1998) 335-339
    • (1998) Curr. Opin. Neurol. , vol.11 , pp. 335-339
    • Przedborski, S.1    Jackson-Lewis, V.2
  • 45
    • 0346463000 scopus 로고    scopus 로고
    • NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia
    • Qin L., Liu Y., Wang T., Wei S.J., Block M.L., Wilson B., Liu B., and Hong J.S. NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia. J. Biol. Chem. 279 (2004) 1415-1421
    • (2004) J. Biol. Chem. , vol.279 , pp. 1415-1421
    • Qin, L.1    Liu, Y.2    Wang, T.3    Wei, S.J.4    Block, M.L.5    Wilson, B.6    Liu, B.7    Hong, J.S.8
  • 46
    • 33750618682 scopus 로고    scopus 로고
    • Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures
    • Reaney S.H., Johnston L.C., Langston W.J., and Di Monte D.A. Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures. Exp. Neurol. 202 (2006) 434-440
    • (2006) Exp. Neurol. , vol.202 , pp. 434-440
    • Reaney, S.H.1    Johnston, L.C.2    Langston, W.J.3    Di Monte, D.A.4
  • 48
    • 0035020470 scopus 로고    scopus 로고
    • Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: similarities with cell loss in Parkinson's disease
    • Rodriguez M., Barroso-Chinea P., Abdala P., Obeso J., and Gonzalez-Hernandez T. Dopamine cell degeneration induced by intraventricular administration of 6-hydroxydopamine in the rat: similarities with cell loss in Parkinson's disease. Exp. Neurol. 169 (2001) 163-181
    • (2001) Exp. Neurol. , vol.169 , pp. 163-181
    • Rodriguez, M.1    Barroso-Chinea, P.2    Abdala, P.3    Obeso, J.4    Gonzalez-Hernandez, T.5
  • 49
    • 4644306054 scopus 로고    scopus 로고
    • Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors
    • Rodriguez-Pallares J., Quiroz C.R., Parga J.A., Guerra M.J., and Labandeira-Garcia J.L. Angiotensin II increases differentiation of dopaminergic neurons from mesencephalic precursors via angiotensin type 2 receptors. Eur. J. Neurosci. 20 (2004) 1489-1498
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 1489-1498
    • Rodriguez-Pallares, J.1    Quiroz, C.R.2    Parga, J.A.3    Guerra, M.J.4    Labandeira-Garcia, J.L.5
  • 51
    • 23944500881 scopus 로고    scopus 로고
    • Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities
    • Saavedra J.M. Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities. Cell. Mol. Neurobiol. 25 (2005) 485-512
    • (2005) Cell. Mol. Neurobiol. , vol.25 , pp. 485-512
    • Saavedra, J.M.1
  • 52
    • 0016411549 scopus 로고
    • Mechanisms of action of 6-hydroxydopamine
    • Sachs C., and Jonsson G. Mechanisms of action of 6-hydroxydopamine. Biochem. Pharmacol. 24 (1975) 1-8
    • (1975) Biochem. Pharmacol. , vol.24 , pp. 1-8
    • Sachs, C.1    Jonsson, G.2
  • 54
    • 0001648468 scopus 로고    scopus 로고
    • Differential role of angiotensin II receptor subtypes on endothelial superoxide formation
    • Sohn H.Y., Raff U., Hoffmann A., Gloe T., Heermeier K., Galle J., and Pohl U. Differential role of angiotensin II receptor subtypes on endothelial superoxide formation. Br. J. Pharmacol. 131 (2000) 667-672
    • (2000) Br. J. Pharmacol. , vol.131 , pp. 667-672
    • Sohn, H.Y.1    Raff, U.2    Hoffmann, A.3    Gloe, T.4    Heermeier, K.5    Galle, J.6    Pohl, U.7
  • 55
    • 0342369569 scopus 로고    scopus 로고
    • Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease
    • Soto-Otero R., Méndez-Álvarez E., Hermida-Ameijeiras A., Muñoz-Patiño A., and Labandeira-García J.L. Autoxidation and neurotoxicity of 6-hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson's disease. J. Neurochem. 74 (2000) 1605-1612
    • (2000) J. Neurochem. , vol.74 , pp. 1605-1612
    • Soto-Otero, R.1    Méndez-Álvarez, E.2    Hermida-Ameijeiras, A.3    Muñoz-Patiño, A.4    Labandeira-García, J.L.5
  • 58
    • 33749514780 scopus 로고    scopus 로고
    • An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections
    • Torres E.M., Meldrum A., Kirik D., and Dunnett S.B. An investigation of the problem of two-layered immunohistochemical staining in paraformaldehyde fixed sections. J. Neurosci. Methods 158 (2006) 64-74
    • (2006) J. Neurosci. Methods , vol.158 , pp. 64-74
    • Torres, E.M.1    Meldrum, A.2    Kirik, D.3    Dunnett, S.B.4
  • 59
    • 4444333896 scopus 로고    scopus 로고
    • Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease
    • Touyz R.M. Reactive oxygen species and angiotensin II signaling in vascular cells - implications in cardiovascular disease. Braz. J. Med. Biol. Res. 37 (2004) 1263-1273
    • (2004) Braz. J. Med. Biol. Res. , vol.37 , pp. 1263-1273
    • Touyz, R.M.1
  • 60
    • 0042233718 scopus 로고    scopus 로고
    • Inhibiting angiotensin receptors in the brain: possible therapeutic implications
    • Unger T. Inhibiting angiotensin receptors in the brain: possible therapeutic implications. Curr. Med. Res. Opin. 19 (2003) 449-451
    • (2003) Curr. Med. Res. Opin. , vol.19 , pp. 449-451
    • Unger, T.1
  • 62
    • 3042595343 scopus 로고    scopus 로고
    • NADPH oxidase contributes to angiotensin II signalling in the nucleus tractus solitarius
    • Wang G., Anrather J., Huang J., Speth R.C., Pickel V., and Iadecola C. NADPH oxidase contributes to angiotensin II signalling in the nucleus tractus solitarius. J. Neurosci. 24 (2004) 5516-5524
    • (2004) J. Neurosci. , vol.24 , pp. 5516-5524
    • Wang, G.1    Anrather, J.2    Huang, J.3    Speth, R.C.4    Pickel, V.5    Iadecola, C.6
  • 63
    • 33747383910 scopus 로고    scopus 로고
    • Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius
    • Wang G., Anrather J., Glass M.J., Tarsitano M.J., Zhou P., Frys K.A., Pickel V.M., and Iadecola C. Nox2, Ca2+, and protein kinase C play a role in angiotensin II-induced free radical production in nucleus tractus solitarius. Hypertension 48 (2006) 482-489
    • (2006) Hypertension , vol.48 , pp. 482-489
    • Wang, G.1    Anrather, J.2    Glass, M.J.3    Tarsitano, M.J.4    Zhou, P.5    Frys, K.A.6    Pickel, V.M.7    Iadecola, C.8
  • 64
    • 0036522967 scopus 로고    scopus 로고
    • Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease
    • Wu D.C., Jackson-Lewis V., Vila M., Tieu K., Teismann P., Vadseth C., Choi D.K., Ischiropoulos H., and Przedborski S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. J. Neurosci. 22 (2002) 1763-1771
    • (2002) J. Neurosci. , vol.22 , pp. 1763-1771
    • Wu, D.C.1    Jackson-Lewis, V.2    Vila, M.3    Tieu, K.4    Teismann, P.5    Vadseth, C.6    Choi, D.K.7    Ischiropoulos, H.8    Przedborski, S.9
  • 68
    • 20044379940 scopus 로고    scopus 로고
    • 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity
    • Zhang W., Qin L., Wang T., Wei S.J., Gao H.M., Liu J., Wilson B., Liu B., Zhang W., Kim H.C., and Hong J.S. 3-hydroxymorphinan is neurotrophic to dopaminergic neurons and is also neuroprotective against LPS-induced neurotoxicity. FASEB J 19 (2005) 395-397
    • (2005) FASEB J , vol.19 , pp. 395-397
    • Zhang, W.1    Qin, L.2    Wang, T.3    Wei, S.J.4    Gao, H.M.5    Liu, J.6    Wilson, B.7    Liu, B.8    Zhang, W.9    Kim, H.C.10    Hong, J.S.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.