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Volumn 13, Issue 18, 2008, Pages 7072-7086

HGF as a renotrophic and anti-fibrotic regulator in chronic renal disease

Author keywords

Extracellular Matrix; HGF; Met; MMP; Myofibroblasts; Renal Fibrosis; Review; TGF beta

Indexed keywords

MUS;

EID: 52049123764     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/3211     Document Type: Article
Times cited : (61)

References (125)
  • 1
    • 0028069634 scopus 로고
    • Loss of glomerular function and tubulointerstitial fibrosis: Cause or effect?
    • A. Ong and L. G. Fine: Loss of glomerular function and tubulointerstitial fibrosis: cause or effect? Kidney Int 45, 345-351 (1994) (Pubitemid 24065065)
    • (1994) Kidney International , vol.45 , Issue.2 , pp. 345-351
    • Ong, A.C.M.1    Fine, L.G.2
  • 2
    • 0030924446 scopus 로고    scopus 로고
    • Angiotensin II in renal fibrosis: Should TGF-β rather than blood pressure be the therapeutic target?
    • N. A. Noble and W. A. Border: Angiotensin II in renal fibrosis: should TGF-beta rather than blood pressure be the therapeutic target? Semin Nephrol 17, 455-466 (1997) (Pubitemid 27398458)
    • (1997) Seminars in Nephrology , vol.17 , Issue.5 , pp. 455-466
    • Noble, N.A.1    Border, W.A.2
  • 3
    • 33845262861 scopus 로고    scopus 로고
    • Renal injury due to renin-angiotensin-aldosterone system activation of the transforming growth factor-β pathway
    • DOI 10.1038/sj.ki.5001846, PII 5001846
    • G. Wolf: Renal injury due to renin-angiotensinaldosterone system activation of the transforming growth factor-beta pathway. Kidney Int 70, 1914-1919 (2006) (Pubitemid 44863378)
    • (2006) Kidney International , vol.70 , Issue.11 , pp. 1914-1919
    • Wolf, G.1
  • 4
    • 22344456349 scopus 로고    scopus 로고
    • Insights into the mechanisms of renal fibrosis: Is it possible to achieve regression?
    • DOI 10.1152/ajprenal.00453.2004
    • C. Chatziantoniou and J. C. Dussaule: Insights into the mechanisms of renal fibrosis: is it possible to achieve regression? Am J Physiol Renal Physiol 289, F227-F234 (2005) (Pubitemid 41003650)
    • (2005) American Journal of Physiology - Renal Physiology , vol.289 , Issue.2
    • Chatziantoniou, C.1    Dussaule, J.-C.2
  • 5
    • 0029985372 scopus 로고    scopus 로고
    • Emerging multipotent aspects of hepatocyte growth factor
    • K. Matsumoto and T. Nakamura: Emerging multipotent aspects of hepatocyte growth factor. J Biochem 119, 591-600 (1996) (Pubitemid 26131762)
    • (1996) Journal of Biochemistry , vol.119 , Issue.4 , pp. 591-600
    • Matsumoto, K.1    Nakamura, T.2
  • 6
    • 0037212712 scopus 로고    scopus 로고
    • Hepatocyte growth factor: From diagnosis to clinical applications
    • DOI 10.1016/S0009-8981(02)00302-9, PII S0009898102003029
    • H. Funakoshi and T. Nakamura: Hepatocyte growth factor: from diagnosis to clinical applications. Clin Chim Acta 327, 1-23 (2003) (Pubitemid 35447813)
    • (2003) Clinica Chimica Acta , vol.327 , Issue.1-2 , pp. 1-23
    • Funakoshi, H.1    Nakamura, T.2
  • 8
    • 0035023230 scopus 로고    scopus 로고
    • Hepatocyte growth factor: Renotropic role and potential therapeutics for renal diseases
    • DOI 10.1046/j.1523-1755.2001.0590062023.x
    • K. Matsumoto and T. Nakamura: Hepatocyte growth factor: renotropic role and potential therapeutics for renal diseases. Kidney Int 59, 2023-2038 (2001) (Pubitemid 32467594)
    • (2001) Kidney International , vol.59 , Issue.6 , pp. 2023-2038
    • Matsumoto, K.1    Nakamura, T.2
  • 9
    • 0036140944 scopus 로고    scopus 로고
    • Hepatocyte growth factor and the kidney
    • DOI 10.1097/00041552-200201000-00004
    • Y. Liu: Hepatocyte growth factor and the kidney. Curr Opin Nephrol Hypertens 11, 23-30 (2002) (Pubitemid 34053334)
    • (2002) Current Opinion in Nephrology and Hypertension , vol.11 , Issue.1 , pp. 23-30
    • Liu, Y.1
  • 10
    • 0031785950 scopus 로고    scopus 로고
    • Hepatocyte growth factor and the kidney: It is not just for the liver
    • D. F. Balkovetz and J. H. Lipschutz: Hepatocyte growth factor and the kidney: it is not just for the liver. Int Rev Cytol 186, 225-260 (1999) (Pubitemid 129751082)
    • (1999) International Review of Cytology , vol.186 , pp. 225-260
    • Balkovetz, D.F.1    Lipschutz, J.H.2
  • 12
    • 34249732042 scopus 로고    scopus 로고
    • Chapter 13. Hepatocyte growth factor: Physiological and therapeutic ligand to attenuate diabetic nephropathy
    • Humana Press, Totawa
    • S. Mizuno and T. Nakamura: Chapter 13. Hepatocyte growth factor: Physiological and therapeutic ligand to attenuate diabetic nephropathy. -Diabetic Kidney. pp225-253 Humana Press, Totawa (2006)
    • (2006) Diabetic Kidney , pp. 225-253
    • Mizuno, S.1    Nakamura, T.2
  • 13
    • 2942635909 scopus 로고    scopus 로고
    • Hepatocyte growth factor in kidney fibrosis: Therapeutic potential and mechanisms of action
    • Y. Liu Y: Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action. Am J Physiol Renal Physiol 287, F7-16 (2004)
    • (2004) Am J Physiol Renal Physiol , vol.287
    • Liu, Y.1
  • 14
    • 0021285134 scopus 로고
    • Partial formation and characterization of hepatocyte growth factor from serum of hepatectomized rats
    • T. Nakamura, K. Nawa and A. Ichihara: Partial purification and characterization of hepatocyte growth factor from serum of hepatectomized rats. Biochem Biophys Res Commun 122, 1450-1459 (1984) (Pubitemid 14073577)
    • (1984) Biochemical and Biophysical Research Communications , vol.122 , Issue.3 , pp. 1450-1459
    • Nakamura, T.1    Nawa, K.2    Ichihara, A.3
  • 18
    • 0025824738 scopus 로고
    • Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor
    • R. Montesano, K. Matsumoto, T. Nakamura and L. Orci: Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factor. Cell 67, 901-908 (1991) (Pubitemid 121001504)
    • (1991) Cell , vol.67 , Issue.5 , pp. 901-908
    • Montesano, R.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4
  • 19
    • 0033936062 scopus 로고    scopus 로고
    • Hepatocyte growth factor in renal regeneration, renal disease and potential therapeutics
    • DOI 10.1097/00041552-200007000-00011
    • K. Matsumoto, S. Mizuno S and T. Nakamura: Hepatocyte growth factor in renal regeneration, renal disease and potential therapeutics. Curr Opin Nephrol Hypertens 9, 395-402 (2000) (Pubitemid 30451695)
    • (2000) Current Opinion in Nephrology and Hypertension , vol.9 , Issue.4 , pp. 395-402
    • Matsumoto, K.1    Mizuno, S.2    Nakamura, T.3
  • 20
    • 7344240472 scopus 로고    scopus 로고
    • Potential role of hepatocyte growth factor in the maintenance of renal structure: Anti-apoptotic action of HGF on epithelial cells
    • DOI 10.1046/j.1523-1755.1998.00092.x
    • Y. Yo, R. Morishita, S. Nakamura, N. Tomita, K. Yamamoto, A. Moriguchi, K. Matsumoto, T. Nakamura, J. Higaki and T. Ogihara: Potential role of hepatocyte growth factor in the maintenance of renal structure: anti-apoptotic action of HGF on epithelial cells. Kidney Int 54, 1128-1138 (1998) (Pubitemid 28449899)
    • (1998) Kidney International , vol.54 , Issue.4 , pp. 1128-1138
    • Yo, Y.1    Morishita, R.2    Nakamura, S.3    Tomita, N.4    Yamamoto, K.5    Moriguchi, A.6    Matsumoto, K.7    Nakamura, T.8    Higaki, J.9    Ogihara, T.10
  • 21
    • 0032577227 scopus 로고    scopus 로고
    • Hepatocyte growth factor protects renal epithelial cells from apoptotic cell death
    • DOI 10.1006/bbrc.1998.8676
    • Y. Liu, A. M. Sun and L. D. Dworkin: Hepatocyte growth factor protects renal epithelial cells from apoptotic cell death. Biochem Biophys Res Commun 246, 821-826 (1998) (Pubitemid 28420942)
    • (1998) Biochemical and Biophysical Research Communications , vol.246 , Issue.3 , pp. 821-826
    • Liu, Y.1    Sun, A.M.2    Dworkin, L.D.3
  • 24
    • 0028154033 scopus 로고
    • Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats
    • S. B. Miller, D. R. Martin, J. Kissane and M. R. Hammerman: Hepatocyte growth factor accelerates recovery from acute ischemic renal injury in rats. Am J Physiol Renal Physiol 266, F129-F134 (1994)
    • (1994) Am J Physiol Renal Physiol , vol.266
    • Miller, S.B.1    Martin, D.R.2    Kissane, J.3    Hammerman, M.R.4
  • 25
    • 0026669204 scopus 로고
    • Hepatocyte growth factor induces urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in MDCK epithelial cells
    • M. S. Pepper, K. Matsumoto, T. Nakamura, L. Orci and R. Montesano: Hepatocyte growth factor induces urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in MDCK epithelial cells. J Biol Chem 267, 20493-20496 (1992)
    • (1992) J Biol Chem , vol.267 , pp. 20493-20496
    • Pepper, M.S.1    Matsumoto, K.2    Nakamura, T.3    Orci, L.4    Montesano, R.5
  • 26
    • 0026601840 scopus 로고
    • Hepatocyte growth factor is a paracrine factor for renal epithelial cells: Stimulation of DNA synthesis and Na,K-ATPase activity
    • K. Ishibashi, S. Sasaki, H. Sakamoto, Y. Nakamura, T. Hata, T. Nakamura and F. Marumo: Hepatocyte growth factor is a paracrine factor for renal epithelial cells: Stimulation of DNA synthesis and Na,K-ATPase activity. Biochem Biophys Res Commun 182, 960-965 (1992)
    • (1992) Biochem Biophys Res Commun , vol.182 , pp. 960-965
    • Ishibashi, K.1    Sasaki, S.2    Sakamoto, H.3    Nakamura, Y.4    Hata, T.5    Nakamura, T.6    Marumo, F.7
  • 28
    • 0029557091 scopus 로고
    • The hepatocyte growth factor/scatter factor (HGF/SF) receptor, met, transduces a morphogenetic signal in renal glomerular fibromuscular mesangial cells
    • M. Kolatsi-Joannou, A. S. Woolf, P. Hardman, S. J. White, M. Gordge and R. M. Henderson: The hepatocyte growth factor/scatter factor (HGF/SF) receptor, met, transduces a morphogenetic signal in renal glomerular fibromuscular mesangial cells. J Cell Sci 108, 3703-3714 (1995) (Pubitemid 26003204)
    • (1995) Journal of Cell Science , vol.108 , Issue.12 , pp. 3703-3714
    • Kolatsi-Joannou, M.1    Woolf, A.S.2    Hardman, P.3    White, S.J.4    Gordge, M.5    Henderson, R.M.6
  • 29
    • 33845725148 scopus 로고    scopus 로고
    • HGF protects rat mesangial cells from high-glucose-mediated oxidative stress
    • DOI 10.1159/000097368
    • H. Li, T. Jiang, Y. Lin, Z. Zhao and N. Zhang: HGF protects rat mesangial cells from high-glucose-mediated oxidative stress. Am J Nephrol 26, 519-530 (2006) (Pubitemid 44971745)
    • (2006) American Journal of Nephrology , vol.26 , Issue.5 , pp. 519-530
    • Li, H.1    Jiang, T.2    Lin, Y.3    Zhao, Z.4    Zhang, N.5
  • 30
    • 27544472284 scopus 로고    scopus 로고
    • HGF modulates H2O2-induced mesangial cell apoptosis through induction of heme oxygenase-1
    • N. Radhakrishnan, M. Bhaskaran and P. C. Singhal: HGF modulates H2O2-induced mesangial cell apoptosis through induction of heme oxygenase-1. Nephron Physiol 101, 92-98 (2005)
    • (2005) Nephron Physiol , vol.101 , pp. 92-98
    • Radhakrishnan, N.1    Bhaskaran, M.2    Singhal, P.C.3
  • 31
    • 0035142883 scopus 로고    scopus 로고
    • Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis
    • A. Fornoni, H. Li, A. Foschi, G. E. Striker and L. J. Striker: Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis. Am J Pathol 158, 275-280 (2001) (Pubitemid 32096493)
    • (2001) American Journal of Pathology , vol.158 , Issue.1 , pp. 275-280
    • Fornoni, A.1    Li, H.2    Foschi, A.3    Striker, G.E.4    Striker, L.J.5
  • 32
    • 0043127400 scopus 로고    scopus 로고
    • Hepatocyte growth factor stimulating endothelial cell growth and accelerating glomerular capillary repair in experimental progressive glomerulonephritis
    • T. Mori, A. Shimizu, Y. Masuda, Y. Fukuda and N. Yamanaka: Hepatocyte growth factor stimulating endothelial cell growth and accelerating glomerular capillary repair in experimental progressive glomerulonephritis. Nephron Exp Nephrol 94, 44-54 (2003)
    • (2003) Nephron Exp Nephrol , vol.94 , pp. 44-54
    • Mori, T.1    Shimizu, A.2    Masuda, Y.3    Fukuda, Y.4    Yamanaka, N.5
  • 33
    • 0032189977 scopus 로고    scopus 로고
    • Developmental roles of HGF/SF and its receptor, the c-met tyrosine kinase
    • DOI 10.1016/S0962-8924(98)01359-2
    • C. Birchmeier and E. Gherardi: Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase. Trends Cell Biol 8, 404-410 (1998) (Pubitemid 28458706)
    • (1998) Trends in Cell Biology , vol.8 , Issue.10 , pp. 404-410
    • Birchmeier, C.1    Gherardi, E.2
  • 36
    • 0030920504 scopus 로고    scopus 로고
    • Activation of Met tyrosine kinase by hepatocyte growth factor is essential for internal organogenesis in Xenopus embryo
    • DOI 10.1006/bbrc.1997.6567
    • S. Aoki, K. Takahashi, K. Matsumoto and T. Nakamura: Activation of Met tyrosine kinase by hepatocyte growth factor is essential for internal organogenesis in Xenopus embryo. Biochem Biophys Res Commun 234, 8-14 (1997) (Pubitemid 27267521)
    • (1997) Biochemical and Biophysical Research Communications , vol.234 , Issue.1 , pp. 8-14
    • Aoki, S.1    Takahashi, K.2    Matsumoto, K.3    Nakamura, T.4
  • 37
    • 0023102242 scopus 로고
    • Compensatory renal growth: Interactions of nephrectomy serum and urine antisera leading to a new theory of renal growth regulation
    • B. W. Snow, W. F. Tarry and J. W. Duckett: Compensatory renal growth: interactions of nephrectomy serum and urine antisera leading to a new theory of renal growth regulation. Urol Res 15, 1-4 (1987) (Pubitemid 17013487)
    • (1987) Urological Research , vol.15 , Issue.1 , pp. 1-4
    • Snow, B.W.1    Tarry, W.F.2    Duckett, J.W.3
  • 39
    • 0027129823 scopus 로고
    • Marked induction of hepatocyte growth factor mRNA in intact kidney and spleen in response to injury of distant organs
    • S. Kono, M. Nagaike, K. Matsumoto and T. Nakamura: Marked induction of hepatocyte growth factor mRNA in intact kidney and spleen in response to injury of distant organs. Biochem Biophys Res Commun 186, 991-998 (1992)
    • (1992) Biochem Biophys Res Commun , vol.186 , pp. 991-998
    • Kono, S.1    Nagaike, M.2    Matsumoto, K.3    Nakamura, T.4
  • 40
    • 19544375968 scopus 로고    scopus 로고
    • Prevention of neutrophil extravasation by hepatocyte growth factor leads to attenuations of tubular apoptosis and renal dysfunction in mouse ischemic kidneys
    • S. Mizuno and T. Nakamura: Prevention of neutrophil extravasation by hepatocyte growth factor leads to attenuations of tubular apoptosis and renal dysfunction in mouse ischemic kidneys. Am J Pathol 166, 1895-1905 (2005) (Pubitemid 40734411)
    • (2005) American Journal of Pathology , vol.166 , Issue.6 , pp. 1895-1905
    • Mizuno, S.1    Nakamura, T.2
  • 41
    • 38849207769 scopus 로고    scopus 로고
    • Inhibition of tubular cell proliferation by neutralizing endogenous HGF leads to renal hypoxia and bone marrow-derived cell engraftment in acute renal failure
    • DOI 10.1152/ajprenal.00480.2007
    • H. Ohnishi, S. Mizuno and T. Nakamura: Inhibition of tubular cell proliferation by neutralizing endogenous HGF leads to renal hypoxia and bone marrow-derived cell engraftment in acute renal failure. Am J Physiol Renal Physiol 294, F326-F335 (2008) (Pubitemid 351199397)
    • (2008) American Journal of Physiology - Renal Physiology , vol.294 , Issue.2
    • Ohnishi, H.1    Mizuno, S.2    Nakamura, T.3
  • 42
    • 0008553220 scopus 로고
    • Hepatocyte growth factor as a renotropic factor and therapeutic potential for acute renal failure
    • M.S. Goligorosky, ed Churchill: Livingstone
    • K. Matsumoto and T. Nakamura: Hepatocyte growth factor as a renotropic factor and therapeutic potential for acute renal failure. -Acute Renal Failure: Emerging New Concepts and Therapeutic Strategies (M.S. Goligorosky, ed) Churchill: Livingstone, p450-p474 (1995)
    • (1995) Acute Renal Failure: Emerging New Concepts and Therapeutic Strategies
    • Matsumoto, K.1    Nakamura, T.2
  • 47
    • 0031018464 scopus 로고    scopus 로고
    • Production of hepatocyte growth factor is increased in chronic renal failure
    • K. Sugimura, C. C. Lee, T. Kim, T. Goto, S. Kasai, K. Harimoto, S. Yamagami and K. Kishimoto: Production of hepatocyte growth factor is increased in chronic renal failure. Nephron 75, 7-12 (1997) (Pubitemid 27052930)
    • (1997) Nephron , vol.75 , Issue.1 , pp. 7-12
    • Sugimura, K.1
  • 48
    • 0030659825 scopus 로고    scopus 로고
    • Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats
    • N. Nakano, A. Moriguchi, R. Morishita, I. Kida, N. Tomita, K. Matsumoto, T. Nakamura, J. Higaki and T. Ogihara: Role of angiotensin II in the regulation of a novel vascular modulator, hepatocyte growth factor (HGF), in experimental hypertensive rats. Hypertension 30:1448-1454 (1997) (Pubitemid 27528088)
    • (1997) Hypertension , vol.30 , Issue.6 , pp. 1448-1454
    • Nakano, N.1    Moriguchi, A.2    Morishita, R.3    Kida, I.4    Tomita, N.5    Matsumoto, K.6    Nakamura, T.7    Higaki, J.8    Ogihara, T.9
  • 49
    • 0029842963 scopus 로고    scopus 로고
    • Initiation and progression of diabetic nephropathy
    • H. H. Parving: Initiation and progression of diabetic nephropathy. N Engl J Med 335, 1682-1683 (1996)
    • (1996) N Engl J Med , vol.335 , pp. 1682-1683
    • Parving, H.H.1
  • 52
    • 0035230374 scopus 로고    scopus 로고
    • TGF-β: A crucial component of the pathogenesis of diabetic nephropathy
    • S. Goldfar and F. N. Ziyadeh: TGF-β: a crucial component of the pathogenesis of diabetic nephropathy. Trans Am Clin Climatol Assoc 112, 27-32 (2001)
    • (2001) Trans Am Clin Climatol Assoc , vol.112 , pp. 27-32
    • Goldfar, S.1    Ziyadeh, F.N.2
  • 54
    • 0031668892 scopus 로고    scopus 로고
    • Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus
    • DOI 10.1007/s005920050107
    • B. Kulseng, M. Borset, T. Espevik and A. Sundan: Elevated hepatocyte growth factor in sera from patients with insulin-dependent diabetes mellitus. Acta Diabetol 35: 77-80 (1998) (Pubitemid 28403236)
    • (1998) Acta Diabetologica , vol.35 , Issue.2 , pp. 77-80
    • Kulseng, B.1    Borset, M.2    Espevik, T.3    Sundan, A.4
  • 55
    • 0030475524 scopus 로고    scopus 로고
    • Vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat
    • Y. Liu, E. M. Tolbert, A. M. Sun and L. D. Dworkin: In vivo and in vitro evidence for increased expression of HGF receptor in kidney of diabetic rat. Am J Physiol Renal Physiol 271, F1202-F1210 (1996)
    • (1996) Am J Physiol Renal Physiol , vol.271
    • Liu, Y.1    Tolbert, E.M.2    Sun, A.M.3    Dworkin, L.D.4
  • 57
    • 0346099296 scopus 로고    scopus 로고
    • 1 production by HGF in attenuation of murine diabetic nephropathy
    • S. Mizuno and T. Nakamura: Suppressions of chronic glomerular injuries and TGF-beta1 production by HGF in attenuation of murine diabetic nephropathy. Am J Physiol Renal Physiol 286, F134-F143 (2004) (Pubitemid 38045051)
    • (2004) American Journal of Physiology - Renal Physiology , vol.286 , Issue.1
    • Mizuno, S.1    Nakamura, T.2
  • 58
    • 0031656259 scopus 로고    scopus 로고
    • Negative regulation of local hepatocyte growth factor expression by angiotensin II and transforming growth factor-β in blood vessels: Potential role of HGF in cardiovascular disease
    • N. Nakano, R. Morishita, A. Moriguchi, Y. Nakamura, S. I. Hayashi, M. Aoki, I. Kida, K. Matsumoto, T. Nakamura, J. Higaki and T. Ogihara: Negative regulation of local hepatocyte growth factor expression by angiotensin II and transforming growth factor-beta in blood vessels: potential role of HGF in cardiovascular disease. Hypertension 32, 444-451 (1998) (Pubitemid 28429132)
    • (1998) Hypertension , vol.32 , Issue.3 , pp. 444-451
    • Nakano, N.1    Morishita, R.2    Moriguchi, A.3    Nakamura, Y.4    Hayashi, S.-I.5    Aoki, M.6    Kida, I.7    Matsumoto, K.8    Nakamura, T.9    Higaki, J.10    Ogihara, T.11
  • 59
    • 0026443262 scopus 로고
    • Negative regulation of hepatocyte growth factor gene expression in human lung fibroblasts and leukemic cells by transforming growth factor-beta1 and glucocorticoids
    • K. Matsumoto, H. Tajima, H. Okazaki and T. Nakamura T: Negative regulation of hepatocyte growth factor gene expression in human lung fibroblasts and leukemic cells by transforming growth factor-beta1 and glucocorticoids. J Biol Chem 267, 24917-24920 (1992)
    • (1992) J Biol Chem , vol.267 , pp. 24917-24920
    • Matsumoto, K.1    Tajima, H.2    Okazaki, H.3    Nakamura, T.T.4
  • 60
    • 0014421532 scopus 로고
    • Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis
    • R. A. Risdon, J. C. Sloper and W. H. Wardener: Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis. Lancet 2, 363-366 (1968)
    • (1968) Lancet , vol.2 , pp. 363-366
    • Risdon, R.A.1    Sloper, J.C.2    Wardener, W.H.3
  • 61
    • 0028334128 scopus 로고
    • On the pathogenesis of chronic renal failure in primary glomerulopathies: A view from the interstitium
    • A. Bohle, F. Strutz and G. A. Muller: On the pathogenesis of chronic renal failure in primary glomerulopathies: a view from the interstitium. Exp Nephrol 2, 205-210 (1994) (Pubitemid 24201686)
    • (1994) Experimental Nephrology , vol.2 , Issue.4 , pp. 205-210
    • Bohle, A.1    Strutz, F.2    Muller, G.A.3
  • 62
    • 0031455209 scopus 로고    scopus 로고
    • Diffuse glomerulosclerosis without tubular injury does not directly manifest renal dysfunction in nephrotic mice (ICGN strain)
    • S. Mizuno, B. F. Yue, M. Okamoto, Y. Horikawa and T. Kurosawa: Diffuse glomerulosclerosis without tubular injury does not directly manifest renal dysfunction in nephrotic mice (ICGN strain). Exp Nephrol 5, 498-507 (1997) (Pubitemid 28044471)
    • (1997) Experimental Nephrology , vol.5 , Issue.6 , pp. 498-507
    • Mizuno, S.1    Yue, B.-F.2    Okamoto, M.3    Horikawa, Y.4    Kurosawa, T.5
  • 63
    • 0033931328 scopus 로고    scopus 로고
    • Reciprocal balance of hepatocyte growth factor and transforming growth factor-β1 in renal fibrosis in mice
    • DOI 10.1046/j.1523-1755.2000.00910.x
    • S. Mizuno, K. Matsumoto, T. Kurosawa, Y. Mizuno-Horikawa and T. Nakamura: Reciprocal balance of hepatocyte growth factor and transforming growth factorbeta1 in renal fibrosis in mice. Kidney Int 57, 937-948 (2000) (Pubitemid 30434784)
    • (2000) Kidney International , vol.57 , Issue.3 , pp. 937-948
    • Mizuno, S.1    Matsumoto, K.2    Kurosawa, T.3    Mizuno-Horikawa, Y.4    Nakamura, T.5
  • 64
    • 0035070420 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy
    • DOI 10.1046/j.1523-1755.2001.0590041304.x
    • S. Mizuno, K. Matsumoto and T. Nakamura: Hepatocyte growth factor suppresses interstitial fibrosis in a mouse model of obstructive nephropathy. Kidney Int 59, 1304-1314 (2001) (Pubitemid 32281218)
    • (2001) Kidney International , vol.59 , Issue.4 , pp. 1304-1314
    • Mizuno, S.1    Matsumoto, K.2    Nakamura, T.3
  • 65
    • 0142200415 scopus 로고    scopus 로고
    • Obstructive nephropathy and renal fibrosis: The role of bone morphogenic protein-7 and hepatocyte growth factor
    • S. Klahr and J. Morrissey: Obstructive nephropathy and renal fibrosis: The role of bone morphogenic protein-7 and hepatocyte growth factor. Kidney Int (Suppl), S105-S112 (2003) (Pubitemid 37315516)
    • (2003) Kidney International, Supplement , vol.64 , Issue.87
    • Klahr, S.1    Morrissey, J.2
  • 66
  • 67
    • 0033746079 scopus 로고    scopus 로고
    • Endogenous hepatocyte growth factor ameliorates chronic renal injury by activating matrix degradation pathways
    • Y. Liu, K. Rajur, E. Tolbert and L. D. Dworkin: Endogenous hepatocyte growth factor ameliorates chronic renal injury by activating matrix degradation pathways. Kidney Int 58, 2028-2043 (2000)
    • (2000) Kidney Int , vol.58 , pp. 2028-2043
    • Liu, Y.1    Rajur, K.2    Tolbert, E.3    Dworkin, L.D.4
  • 68
    • 15444362469 scopus 로고    scopus 로고
    • Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES
    • DOI 10.1097/01.ASN.0000141962.44300.3A
    • R. Gong, A. Rifai, E. M. Tolbert, P. Biswas, J. N. Centracchio and L. D. Dworkin: Hepatocyte growth factor ameliorates renal interstitial inflammation in rat remnant kidney by modulating tubular expression of macrophage chemoattractant protein-1 and RANTES. J Am Soc Nephrol 15, 2868-2881 (2004) (Pubitemid 41103396)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.11 , pp. 2868-2881
    • Gong, R.1    Rifai, A.2    Tolbert, E.M.3    Biswas, P.4    Centracchio, J.N.5    Dworkin, L.D.6
  • 69
    • 33748046159 scopus 로고    scopus 로고
    • Anti-inflammatory effect of hepatocyte growth factor in chronic kidney disease: Targeting the inflamed vascular endothelium
    • DOI 10.1681/ASN.2006020185
    • Gong, A. Rifai and L. D. Dworkin: Antiinflammatory effect of hepatocyte growth factor in chronic kidney disease: targeting the inflamed vascular endothelium. J Am Soc Nephrol 17, 2464-2473 (2006) (Pubitemid 44300962)
    • (2006) Journal of the American Society of Nephrology , vol.17 , Issue.9 , pp. 2464-2473
    • Gong, R.1    Rifai, A.2    Dworkin, L.D.3
  • 70
    • 0030738188 scopus 로고    scopus 로고
    • Renal tubular hyperplasia, polycystic disease, and glomerulosclerosis in transgenic mice overexpressing hepatocyte growth factor/scatter factor
    • H. Takayama, W. J. LaRochelle, S. G. Sabnis, T. Otsuka and G. Merlino: Renal tubular hyperplasia, polycystic disease, and glomerulosclerosis in transgenic mice overexpressing hepatocyte growth factor/scatter factor. Lab Invest 77, 131-138 (1997) (Pubitemid 27355909)
    • (1997) Laboratory Investigation , vol.77 , Issue.2 , pp. 131-138
    • Takayama, H.1    LaRochelle, W.J.2    Sabnis, S.G.3    Otsuka, T.4    Merlino, G.5
  • 72
    • 0030044647 scopus 로고    scopus 로고
    • Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator
    • DOI 10.1074/jbc.271.7.3615
    • K. Miyazawa, T. Shimomura, and N. Kitamura: Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator. J Biol Chem 271, 3615-3618 (1996) (Pubitemid 26065675)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.7 , pp. 3615-3618
    • Miyazawa, K.1    Shimomura, T.2    Kitamura, N.3
  • 74
    • 0031819504 scopus 로고    scopus 로고
    • The cell biology of liver fibrogenesis - An imbalance of proliferation, growth arrest and apoptosis of myofibroblasts
    • DOI 10.1007/s004410051073
    • A. M. Gressner: The cell biology of liver fibrogenesis: an imbalance of proliferation, growth arrest and apoptosis of myofibroblasts. Cell Tissue Res 292, 447-452 (1998) (Pubitemid 28282456)
    • (1998) Cell and Tissue Research , vol.292 , Issue.3 , pp. 447-452
    • Gressner, A.M.1
  • 76
    • 0026562550 scopus 로고
    • Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor
    • R. J. Johnson, E. W. Raines, J. Floege, A. Yoshimura, P. Pritzl, C. Alpers and R. Ross: Inhibition of mesangial cell proliferation and matrix expansion in glomerulonephritis in the rat by antibody to platelet-derived growth factor. J Exp Med 175: 1413-1416 (1992)
    • (1992) J Exp Med , vol.175 , pp. 1413-1416
    • Johnson, R.J.1    Raines, E.W.2    Floege, J.3    Yoshimura, A.4    Pritzl, P.5    Alpers, C.6    Ross, R.7
  • 77
    • 0025277164 scopus 로고
    • Suppression of experimental glomerulonephritis by antiserum against transforming growth factor-beta1
    • W. A. Border, S. Okuda, L. R. Languino, M. B. Sporn and E. Ruoslahti: Suppression of experimental glomerulonephritis by antiserum against transforming growth factor-beta1. Nature 346: 371-374 (1990)
    • (1990) Nature , vol.346 , pp. 371-374
    • Border, W.A.1    Okuda, S.2    Languino, L.R.3    Sporn, M.B.4    Ruoslahti, E.5
  • 78
    • 0027138877 scopus 로고
    • Glomerulosclerosis induced by in vivo transfection of transforming growth factor-β or platelet-derived growth factor gene into the rat kidney
    • Y. Isaka, Y. Fujiwara, N. Ueda, Y. Kaneda, T. Kamada and E. Imai: Glomerulosclerosis induced by in vivo transfection of transforming growth factor-beta or plateletderived growth factor gene into the rat kidney. J Clin Invest 92, 2597-2601 (1993) (Pubitemid 24006522)
    • (1993) Journal of Clinical Investigation , vol.92 , Issue.6 , pp. 2597-2601
    • Isaka, Y.1    Fujiwara, Y.2    Ueda, N.3    Kaneda, Y.4    Kamada, T.5    Imai, E.6
  • 79
    • 0037947599 scopus 로고    scopus 로고
    • Counteractive effects of HGF on PDGF-induced mesangial cell proliferation in a rat model of glomerulonephritis
    • K. Bessho, S. Mizuno, K. Matsumoto and T. Nakamura: Counteractive effects of HGF on PDGFinduced mesangial cell proliferation in a rat model of glomerulonephritis. Am J Physiol Renal Physiol 284, F1171-F1180 (2003) (Pubitemid 36578444)
    • (2003) American Journal of Physiology - Renal Physiology , vol.284 , Issue.6
    • Bessho, K.1    Mizuno, S.2    Matsumoto, K.3    Nakamura, T.4
  • 80
    • 17144366279 scopus 로고    scopus 로고
    • Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis
    • W. H. Kim, K. Matsumoto, K. Bessho and T. Nakamura: Growth inhibition and apoptosis in liver myofibroblasts promoted by hepatocyte growth factor leads to resolution from liver cirrhosis. Am J Pathol 166, 1017-1028 (2005) (Pubitemid 40524427)
    • (2005) American Journal of Pathology , vol.166 , Issue.4 , pp. 1017-1028
    • Kim, W.-H.1    Matsumoto, K.2    Bessho, K.3    Nakamura, T.4
  • 81
    • 8144221953 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats
    • DOI 10.1161/01.CIR.0000146342.30470.30
    • M. Ono, Y. Sawa, S. Mizuno, N. Fukushima, H. Ichikawa, K. Bessho, T. Nakamura and H. Matsuda: Hepatocyte growth factor suppresses vascular medial hyperplasia and matrix accumulation in advanced pulmonary hypertension of rats. Circulation 110, 2896-2902 (2004) (Pubitemid 39473615)
    • (2004) Circulation , vol.110 , Issue.18 , pp. 2896-2902
    • Ono, M.1    Sawa, Y.2    Mizuno, S.3    Fukushima, N.4    Ichikawa, H.5    Bessho, K.6    Nakamura, T.7    Matsuda, H.8
  • 82
    • 0028109801 scopus 로고
    • Transforming growth factor β in tissue fibrosis
    • DOI 10.1056/NEJM199411103311907
    • W. A. Border and N. A. Noble: Transforming growth factor-beta in tissue fibrosis. N Engl J Med 331, 1286-1292 (1994) (Pubitemid 24333194)
    • (1994) New England Journal of Medicine , vol.331 , Issue.19 , pp. 1286-1292
    • Border, W.A.1    Noble, N.A.2
  • 83
    • 0028362076 scopus 로고
    • Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-β expression in rat glomerular mesangial cells
    • S. Kagami, W. A. Border, D. E. Miller and N. A. Noble: Angiotensin II stimulates extracellular matrix protein synthesis through induction of transforming growth factor-beta expression in rat glomerular mesangial cells. J Clin Invest 93, 2431-2437 (1994) (Pubitemid 24177156)
    • (1994) Journal of Clinical Investigation , vol.93 , Issue.6 , pp. 2431-2437
    • Kagami, S.1    Border, W.A.2    Miller, D.E.3    Noble, N.A.4
  • 84
    • 0031727915 scopus 로고    scopus 로고
    • Targeting TGF-β overexpression in renal disease: Maximizing the antifibrotic action of angiotensin II blockade
    • DOI 10.1046/j.1523-1755.1998.00164.x
    • H. Peters, W. A. Border and N. A. Noble: Targeting TGF-beta overexpression in renal disease: maximizing the antifibrotic action of angiotensin II blockade. Kidney Int 54, 1570-1580 (1998) (Pubitemid 28502899)
    • (1998) Kidney International , vol.54 , Issue.5 , pp. 1570-1580
    • Peters, H.1    Border, W.A.2    Noble, N.A.3
  • 85
    • 0035538365 scopus 로고    scopus 로고
    • Angiotensin II, TGF-beta and renal fibrosis
    • The Renin-Angiotensin System and Progression of Renal Diseases
    • J. Gaedeke, H. Peters, N. A. Noble and W. A, Border: Angiotensin II, TGF-beta and renal fibrosis. Contrib Nephrol 135, 153-160 (2001) (Pubitemid 33352377)
    • (2001) Contributions to Nephrology , vol.135 , pp. 153-160
    • Gaedeke, J.1    Peters, H.2    Noble, N.A.3    Border, W.A.4
  • 87
    • 0036154080 scopus 로고    scopus 로고
    • Essential role(s) of the intrarenal renin-angiotensin system in transforming growth factor-β1 gene expression and induction of hypertrophy of rat kidney proximal tubular cells in high glucose
    • S. L. Zhang, C. To, X. Chen, J. G. Filep, S. S. Tang, J. R. Ingelfinger and J. S. Chan: Essential role(s) of the intrarenal renin-angiotensin system in transforming growth factor-beta1 gene expression and induction of hypertrophy of rat kidney proximal tubular cells in high glucose. J Am Soc Nephrol 13, 302-312 (2002) (Pubitemid 34106271)
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.2 , pp. 302-312
    • Zhang, S.-L.1    To, C.2    Chen, X.3    Filep, J.G.4    Tang, S.-S.5    Ingelfinger, J.R.6    Chan, J.S.D.7
  • 88
    • 2542433088 scopus 로고    scopus 로고
    • Hepatocyte growth factor antagonizes the profibrotic action of TGF-β1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF
    • DOI 10.1097/01.ASN.0000130568.53923.FD
    • C. Dai and Y. Liu: Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF. J Am Soc Nephrol 15, 1402-1412 (2004) (Pubitemid 38679665)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.6 , pp. 1402-1412
    • Dai, C.1    Liu, Y.2
  • 89
    • 0036138824 scopus 로고    scopus 로고
    • Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis
    • J. Yang and Y. Liu: Blockage of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal interstitial fibrosis. J Am Soc Nephrol 13, 96-107 (2002) (Pubitemid 34042016)
    • (2002) Journal of the American Society of Nephrology , vol.13 , Issue.1 , pp. 96-107
    • Yang, J.1    Liu, Y.2
  • 90
    • 0141563590 scopus 로고    scopus 로고
    • Hepatocyte growth factor regulates proteoglycan synthesis in interstitial fibroblasts
    • DOI 10.1046/j.1523-1755.2003.00202.x
    • E. Kobayashi, H. Sasamura, M. Mifune, R. Shimizu-Hirota, M. Kuroda, M. Hayashi and T. Saruta: Hepatocyte growth factor regulates proteoglycan synthesis in interstitial fibroblasts. Kidney Int 64, 1179-1188 (2003) (Pubitemid 37153782)
    • (2003) Kidney International , vol.64 , Issue.4 , pp. 1179-1188
    • Kobayashi, E.1    Sasamura, H.2    Mifune, M.3    Shimizu-Hirota, R.4    Kuroda, M.5    Hayashi, M.6    Saruta, T.7
  • 91
    • 0037315742 scopus 로고    scopus 로고
    • Hepatocyte growth factor counteracts transforming growth factor-beta1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6-nephrectomized mice
    • T. Inoue, H. Okada, T. Kobayashi, Y. Watanabe, Y. Kanno, J. B. Kopp, T. Nishida, M. Takigawa, M. Ueno, T. Nakamura and H. Suzuki: Hepatocyte growth factor counteracts transforming growth factor-beta1, through attenuation of connective tissue growth factor induction, and prevents renal fibrogenesis in 5/6-nephrectomized mice. FASEB J 17, 268-270 (2003)
    • (2003) FASEB J , vol.17 , pp. 268-270
    • Inoue, T.1    Okada, H.2    Kobayashi, T.3    Watanabe, Y.4    Kanno, Y.5    Kopp, J.B.6    Nishida, T.7    Takigawa, M.8    Ueno, M.9    Nakamura, T.10    Suzuki, H.11
  • 92
    • 0036172597 scopus 로고    scopus 로고
    • Hepatocyte growth factor induces collagenase (matrix metalloproteinase-1) via the transcription factor Ets-1 in human hepatic stellate cell line
    • DOI 10.1016/S0168-8278(01)00245-8, PII S0168827801002458
    • I. Ozaki, G. Zhao, T. Mizuta, Y. Ogawa, T. Hara, S. Kajihara, A. Hisatomi, T. Sakai and K. Yamamoto. HGF induces collagenase (matrix metalloproteinase-1) via the transcription factor Ets-1 in human hepatic stellate cell line. J Hepatol 36, 169-178 (2002) (Pubitemid 34146423)
    • (2002) Journal of Hepatology , vol.36 , Issue.2 , pp. 169-178
    • Ozaki, I.1    Zhao, G.2    Mizuta, T.3    Ogawa, Y.4    Hara, T.5    Kajihara, S.6    Hisatomi, A.7    Sakai, T.8    Yamamoto, K.9
  • 93
    • 0029146465 scopus 로고
    • Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats
    • Y. Matsuda, K. Matsumoto, T. Ichida and T. Nakamura: Hepatocyte growth factor suppresses the onset of liver cirrhosis and abrogates lethal hepatic dysfunction in rats. J Biochem 118, 643-649 (1995)
    • (1995) J Biochem , vol.118 , pp. 643-649
    • Matsuda, Y.1    Matsumoto, K.2    Ichida, T.3    Nakamura, T.4
  • 94
    • 0034636783 scopus 로고    scopus 로고
    • Potential contribution of a novel antifibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters
    • Y. Taniyama, R. Morishita, H. Nakagami, A. Moriguchi, H. Sakonjo, S. Kim, K. Matsumoto, T. Nakamura, J. Higaki and T. Ogihara: Potential contribution of a novel anti-fibrotic factor, hepatocyte growth factor, to prevention of myocardial fibrosis by angiotensin II blockade in cardiomyopathic hamsters. Circulation 102, 246-252 (2000) (Pubitemid 30451784)
    • (2000) Circulation , vol.102 , Issue.2 , pp. 246-252
    • Taniyama, Y.1    Morishita, R.2    Nakagami, H.3    Moriguchi, A.4    Sakonjo, H.5    Kim, S.6    Matsumoto, K.7    Nakamura, T.8    Higaki, J.9    Ogihara, T.10
  • 95
    • 16344367737 scopus 로고    scopus 로고
    • HGF reduces advancing lung fibrosis in mice: A potential role for MMP-dependent myofibroblast apoptosis
    • DOI 10.1096/fj.04-1535fje
    • S. Mizuno, K. Matsumoto, M. Y. Li and T. Nakamura: HGF reduces advancing lung fibrosis in mice: a potential role for MMP-dependent myofibroblast apoptosis. FASEB J 19, 580-582 (2005) (Pubitemid 40471250)
    • (2005) FASEB Journal , vol.19 , Issue.6 , pp. 580-582
    • Mizuno, S.1    Matsumoto, K.2    Li, M.-Y.3    Nakamura, T.4
  • 96
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion-dependent cell survival by focal adhesion kinase
    • S. M. Frisch, K. Vuori, E. Ruoslahti and P. Y. Chan-Hui: Control of adhesion-dependent cell survival by focal adhesion kinase. J Cell Biol 134, 793-799 (1996) (Pubitemid 26269148)
    • (1996) Journal of Cell Biology , vol.134 , Issue.3 , pp. 793-799
    • Frisch, S.M.1    Vuori, K.2    Ruoslahti, E.3    Chan-Hui, P.-Y.4
  • 97
    • 0032146551 scopus 로고    scopus 로고
    • Mechanisms of spontaneous resolution of rat liver fibrosis: Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors
    • J. P. Iredale, R. C. Benyon, J. Pickering, M. McCullen, M. Northrop, S. Pawley C. Hovell and M. J. Arthur: Mechanisms of spontaneous resolution of rat liver fibrosis: Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors. J Clin Invest 102, 538-549 (1998) (Pubitemid 28376157)
    • (1998) Journal of Clinical Investigation , vol.102 , Issue.3 , pp. 538-549
    • Iredale, J.P.1    Benyon, R.C.2    Pickering, J.3    McCullen, M.4    Northrop, M.5    Pawley, S.6    Hovell, C.7    Arthur, M.J.P.8
  • 98
    • 0034830886 scopus 로고    scopus 로고
    • Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
    • M. C. Wright, R. Issa, D. E. Smart, N. Trim, G. I. Murray, J. N. Primrose, M. J. Arthur, J. P. Iredale and D. A. Mann: Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats. Gastroenterology 121, 685-698 (2001) (Pubitemid 32822584)
    • (2001) Gastroenterology , vol.121 , Issue.3 , pp. 685-698
    • Wright, M.C.1    Issa, R.2    Smart, D.E.3    Trim, N.4    Murray, G.I.5    Primrose, J.N.6    Arthur, M.J.P.7    Iredale, J.P.8    Mann, D.A.9
  • 99
    • 0028116649 scopus 로고
    • Mesangial cell apoptosis: The major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis
    • A. J. Baker, A. Mooney, J. Hughes, D. Lombardi, R. J. Johnson and J. Savill: Mesangial cell apoptosis: the major mechanism for resolution of glomerular hypercellularity in experimental mesangial proliferative nephritis. J Clin Invest 94, 2105-2116 (1994) (Pubitemid 24348252)
    • (1994) Journal of Clinical Investigation , vol.94 , Issue.5 , pp. 2105-2116
    • Baker, A.J.1    Mooney, A.2    Hughes, J.3    Lombardi, D.4    Johnson, R.J.5    Savill, J.6
  • 100
    • 0028851160 scopus 로고
    • Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar
    • A, Desmouliere, M. Redard, I. Darby and G. Gabbiani: Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol 146, 56-66 (1995)
    • (1995) Am J Pathol , vol.146 , pp. 56-66
    • Desmouliere, A.1    Redard, M.2    Darby, I.3    Gabbiani, G.4
  • 101
    • 0037302457 scopus 로고    scopus 로고
    • Delayed administration of hepatocyte growth factor reduces renal fibrosis in obstructive nephropathy
    • J. Yang and Y. Liu: Delayed administration of hepatocyte growth factor reduces renal fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol 284, F349-F357 (2003) (Pubitemid 36114697)
    • (2003) American Journal of Physiology - Renal Physiology , vol.284 , Issue.2
    • Yang, J.1    Liu, Y.2
  • 102
    • 33746154515 scopus 로고    scopus 로고
    • HGF gene therapy attenuates renal allograft scarring by preventing the profibrotic inflammatory-induced mechanisms
    • DOI 10.1038/sj.ki.5001510, PII 5001510
    • I. Herrero-Fresneda, J. Torras, M. Franquesa, A. Vidal, J. M. Cruzado, N. Lloberas, C. Fillat and J. M. Grinyo: HGF gene therapy attenuates renal allograft scarring by preventing the profibrotic inflammatoryinduced mechanisms. Kidney Int 70, 265-274 (2006) (Pubitemid 44086576)
    • (2006) Kidney International , vol.70 , Issue.2 , pp. 265-274
    • Herrero-Fresneda, I.1    Torras, J.2    Franquesa, M.3    Vidal, A.4    Cruzado, J.M.5    Lloberas, N.6    Fillat, C.7    Grinyo, J.M.8
  • 106
    • 15444376904 scopus 로고    scopus 로고
    • Activation of PI3K-Akt-GSK3β pathway mediates hepatocyte growth factor inhibition of RANTES expression in renal tubular epithelial cells
    • DOI 10.1016/j.bbrc.2005.02.122
    • R. Gong, A. Rifai and L. D. Dworkin: Activation of PI3K-Akt-GSK3beta pathway mediates hepatocyte growth factor inhibition of RANTES expression in renal tubular epithelial cells. Biochem Biophys Res Commun 330: 27-33 (2005) (Pubitemid 40394931)
    • (2005) Biochemical and Biophysical Research Communications , vol.330 , Issue.1 , pp. 27-33
    • Gong, R.1    Rifai, A.2    Dworkin, L.D.3
  • 107
    • 43149122725 scopus 로고    scopus 로고
    • Hepatocyte growth factor suppresses proinflammatory NFkappaB activation through GSK3-beta inactivation in renal tubular epithelial cells
    • R. Gong, A. Rifai, Y. Ge, S. Chen and L. D. Dworkin: Hepatocyte growth factor suppresses proinflammatory NFkappaB activation through GSK3-beta inactivation in renal tubular epithelial cells. J Biol Chem 283: 7401-7410 (2008)
    • (2008) J Biol Chem , vol.283 , pp. 7401-7410
    • Gong, R.1    Rifai, A.2    Ge, Y.3    Chen, S.4    Dworkin, L.D.5
  • 109
    • 0020324688 scopus 로고
    • Dietary protein intake and the progressive nature of kidney disease: The role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease
    • B. M. Brenner, T. W. Meyer and T. H. Hostetter: Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease. N Engl J Med 307, 652-659 (1982) (Pubitemid 12049914)
    • (1982) New England Journal of Medicine , vol.307 , Issue.11 , pp. 652-659
    • Brenner, B.M.1    Meyer, T.W.2    Hostetter, T.H.3
  • 110
    • 15844397902 scopus 로고    scopus 로고
    • Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice
    • DOI 10.1097/01.ASN.0000139479.09658.EE
    • C. Dai, J. Yang, S. Bastacky, J. Xia, Y. Li and Y. Liu: Intravenous administration of hepatocyte growth factor gene ameliorates diabetic nephropathy in mice. J Am Soc Nephrol 15, 2637-2647 (2004) (Pubitemid 41103370)
    • (2004) Journal of the American Society of Nephrology , vol.15 , Issue.10 , pp. 2637-2647
    • Dai, C.1    Yang, J.2    Bastacky, S.3    Xia, J.4    Li, Y.5    Liu, Y.6
  • 112
    • 0029881935 scopus 로고    scopus 로고
    • Delayed treatment with enalapril halts tubulointerstitial fibrosis in rats with obstructive nephropathy
    • S. Ishidoya, J. Morrissey, R. McCracken and S. Klahr: Delayed treatment with enalapril halts tubulointerstitial fibrosis in rats with obstructive nephropathy. Kidney Int 49, 1110-1119 (1996) (Pubitemid 26122714)
    • (1996) Kidney International , vol.49 , Issue.4 , pp. 1110-1119
    • Ishidoya, S.1    Morrissey, J.2    Mccracken, R.3    Klahr, S.4
  • 113
    • 0032870244 scopus 로고    scopus 로고
    • Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats
    • K. Matsumoto, R. Morishita, A. Moriguchi, N. Tomita, Y. Yo, T. Nishii, T. Nakamura, J. Higaki and T. Ogihara: Prevention of renal damage by angiotensin II blockade, accompanied by increased renal hepatocyte growth factor in experimental hypertensive rats. Hypertension 34, 279-284 (1999) (Pubitemid 29409228)
    • (1999) Hypertension , vol.34 , Issue.2 , pp. 279-284
    • Matsumoto, K.1    Morishita, R.2    Moriguchi, A.3    Tomita, N.4    Yo, Y.5    Nishii, T.6    Matsumoto, K.7    Nakamura, T.8    Higaki, J.9    Ogihara, T.10
  • 114
    • 0036785218 scopus 로고    scopus 로고
    • Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice
    • J. Yang, C. Dai and Y. Liu. Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice. J Am Soc Nephrol 13, 2464-2477 (2002)
    • (2002) J Am Soc Nephrol , vol.13 , pp. 2464-2477
    • Yang, J.1    Dai, C.2    Liu, Y.3
  • 115
    • 34249665546 scopus 로고    scopus 로고
    • Hepatocyte growth factor: A regenerative drug for acute hepatitis and liver cirrhosis
    • DOI 10.2217/17460751.2.2.161
    • S. Mizuno and T. Nakamura: Hepatocyte growth factor: a regenerative drug for acute hepatitis and liver cirrhosis. Regen Med 2, 161-170 (2007) (Pubitemid 46831077)
    • (2007) Regenerative Medicine , vol.2 , Issue.2 , pp. 161-170
    • Mizuno, S.1    Nakamura, T.2
  • 116
    • 31744439280 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D3 inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression
    • DOI 10.1111/j.1523-1755.2005.00562.x, PII 4494753
    • Y. Li, B. C. Spataro, J. Yang, C. Dai and Y. Liu: 1,25-dihydroxyvitamin D inhibits renal interstitial myofibroblast activation by inducing hepatocyte growth factor expression. Kidney Int 68, 1500-1510 (2005) (Pubitemid 43173380)
    • (2005) Kidney International , vol.68 , Issue.4 , pp. 1500-1510
    • Li, Y.1    Spataro, B.C.2    Yang, J.3    Dai, C.4    Liu, Y.5
  • 117
    • 33645454825 scopus 로고    scopus 로고
    • Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferatoractivated receptor-gamma agonists
    • Y. Li, X. Wen, B. C. Spataro, K. Hu, C. Dai and Y. Liu: Hepatocyte growth factor is a downstream effector that mediates the antifibrotic action of peroxisome proliferatoractivated receptor-gamma agonists. J Am Soc Nephrol 17, 54-65 (2006)
    • (2006) J Am Soc Nephrol , vol.17 , pp. 54-65
    • Li, Y.1    Wen, X.2    Spataro, B.C.3    Hu, K.4    Dai, C.5    Liu, Y.6
  • 118
    • 0742306757 scopus 로고    scopus 로고
    • Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma
    • DOI 10.1038/sj.gt.3302165
    • M. H. Wu, H. Yokozeki, S. Takagawa, T. Yamamoto, T. Satoh, Y. Kaneda, I. Katayama and K. Nishioka: Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma. Gene Ther 11, 170-180 (2004) (Pubitemid 38159689)
    • (2004) Gene Therapy , vol.11 , Issue.2 , pp. 170-180
    • Wu, M.-H.1    Yokozeki, H.2    Takagawa, S.3    Yamamoto, T.4    Satoh, T.5    Kaneda, Y.6    Katayama, I.7    Nishioka, K.8
  • 121
    • 3543025721 scopus 로고    scopus 로고
    • Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease
    • DOI 10.1161/01.HYP.0000136394.08900.ed
    • R. Morishita, M. Aoki, N. Hayashi, H. Makino, K. Yamasaki, J. Azuma, Y. Sawa, H. Matsuda, Y. Kaneda and T. Ogihara: Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Hypertension 44, 203-209 (2004) (Pubitemid 39014240)
    • (2004) Hypertension , vol.44 , Issue.2 , pp. 203-209
    • Morishita, R.1    Aoki, M.2    Hashiya, N.3    Makino, H.4    Yamasaki, K.5    Azuma, J.6    Sawa, Y.7    Matsuda, H.8    Kaneda, Y.9    Ogihara, T.10
  • 122
    • 2442681478 scopus 로고    scopus 로고
    • Electroporation-mediated HGF gene transfer ameliorated cyclosporine nephrotoxicity
    • DOI 10.1111/j.1523-1755.2004.00625.x
    • M. Mizui, Y. Isaka, Y. Takabatake, S. Mizuno, T. Nakamura, T. Ito, E. Imai and M. Hori: Electroporationmediated HGF gene transfer ameliorated cyclosporine nephrotoxicity. Kidney Int 65, 2041-2053 (2004) (Pubitemid 38669990)
    • (2004) Kidney International , vol.65 , Issue.6 , pp. 2041-2053
    • Mizui, M.1    Isaka, Y.2    Takabatake, Y.3    Mizuno, S.4    Nakamura, T.5    Ito, T.6    Imai, E.7    Hori, M.8
  • 123
    • 1842471191 scopus 로고    scopus 로고
    • Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats
    • DOI 10.1093/ndt/gfh064
    • K. Yazawa, Y. Isaka, S. Takahara, E. Imai, N. Ichimaru, Y. Shi, Y. Namba and A. Okuyama: Direct transfer of hepatocyte growth factor gene into kidney suppresses cyclosporin A nephrotoxicity in rats. Nephrol Dial Transplant 19, 812-816 (2004) (Pubitemid 38455650)
    • (2004) Nephrology Dialysis Transplantation , vol.19 , Issue.4 , pp. 812-816
    • Yazawa, K.1    Isaka, Y.2    Takahara, S.3    Imai, E.4    Ichimaru, N.5    Shi, Y.6    Namba, Y.7    Okuyama, A.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.